Medicine and Health Sciences Commons^™

An Atypical Case Of Herpes Simplex 1 Meningitis, Nadim Ojaimi, Sofia Zhang, Marcos Wolff, Christopher James Haas

Journal of Community Hospital Internal Medicine Perspectives

Herpes simplex virus (HSV) is well known to cause Central Nervous System (CNS) infections, ranging from more common HSV-2 viral meningitis to the more rare and severe HSV-1 encephalitis. Here we present an atypical case of aseptic meningitis due to HSV-1. Intriguingly, despite the potential severity of HSV-1 infections, the patient had an uncomplicated course with only mild symptoms that resolved with conservative management alone. This case report aims to provide a frame of reference for the non-specific presentation of a patient with uncommon HSV-1 meningitis.

Sevelamer-Induced Gastrointestinal Mucosal Injury: A Critical Review For Clinicians, Lefika Bathobakae, Phenyo Phuu, Saif Yasin, Rammy Bashir, Jessica Escobar, Ruhin Yuridullah, Gabriel Melki, Mohamed Elagami, Yana Cavanagh, Walid Baddoura

Journal of Community Hospital Internal Medicine Perspectives

Sevelamer is a non-absorbable polymer used to treat hyperphosphatemia in individuals with end-stage renal disease (ESRD) undergoing hemodialysis. The deposition of sevelamer crystals in the gastrointestinal (GI) tract, especially in the colon, can cause mucosal inflammation, pseudopolyps, ulceration, ischemia, or necrosis. Owing to its rarity and lack of physician awareness, the actual incidence and prevalence of sevelamer-induced gastrointestinal mucosal injury (SIGMI) remain unknown. The current evidence is retrospective, in the form of observational studies. This systematic review of case reports provides an overview of SIGMI, with a focus on its etiology, signs and symptoms, pathogenesis, diagnosis, and management. Electronic databases, …

New Era – Same Perspective, Surendra Marur, Gillian Junker

Journal of Community Hospital Internal Medicine Perspectives

Brief history of JCHIMP, future direction and acknowledgement of our 2023 peer reviewers and sources of our authors.

2024-25 Women In Science Conference Schedule (Pdf), Lynn University

Women in Science Conference

2024-25 Women in Environmental Science Conference Schedule (PDF)

Antibacterial And Wound Healing Stimulant Nanofibrous Dressing Consisting Of Soluplus And Soy Protein Isolate Loaded With Mupirocin., Maryam Jahani, Azadeh Asefnejad, Mastafa H Al-Musawi, Ahmed A Mohammed, Basma Talib Al-Sudani, Maha Hameed Al-Bahrani, Nada A Kadhim, Mina Shahriari-Khalaji, Hamideh Valizadeh, Fariborz Sharifianjazi, Morteza Mehrjoo, Ketevan Tavamaishvili, Mohamadreza Tavakoli

Rowan-Virtua School of Translational Biomedical Engineering & Sciences Departmental Research

Severe cutaneous injuries may not heal spontaneously and may necessitate the use of supplementary therapeutic methods. Electrospun nanofibers possess high porosity and specific surface area, which provide the necessary microenvironment for wound healing. Here in, the nanofibers of Soluplus-soy protein isolate (Sol-SPI) containing mupirocin (Mp) were fabricated via electrospinning for wound treatment. The fabricated nanofibers exhibited water absorption capacities of about 300.83 ± 29.72% and water vapor permeability values of about 821.8 ± 49.12 g/m2 day. The Sol/SPI/Mp nanofibers showed an in vitro degradability of 33.73 ± 3.55% after 5 days. The ultimate tensile strength, elastic modulus, and elongation of …

Successful Application Of Craniosacral Therapy In A Case Of Colic In An 8-Week-Old Baby, Caro O’Neill, Angie Butterfield

Journal of Transformative Touch

This case study reports on the effectiveness of CranioSacral Therapy (CST) for an eight-week-old baby boy experiencing colic. A CST pediatric protocol was utilized during two sessions, a week apart, in May 2023. An improvement in symptoms was recorded after the first treatment. After the second treatment the baby was no longer presenting with symptoms related to infant colic. This case suggests that CST can be an effective support for babies experiencing infant colic.

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Tak1 Blockade Plus Azacitidine Induces Apoptosis, Augments Cytarabine, And Ablates Clonogenicity In Mll-Af9+ Human Aml Cell Lines, Austin P. Runde, Cameron Lewis, Peter Breslin Sj, Jiwang Zhang

School of Medicine

Acute myeloid leukemia (AML) encompasses a diverse group of cancers that originate in the blood-forming tissues of the bone marrow [1]. Aside from the PML-RARA⁺ subtype, AML carries a 5-year survival rate of 28% for patients 20+ years of age. AML is the most common cancer of the hematopoietic system and is slightly more common in biological males; the average age at diagnosis is 68 years. Standard frontline treatment for AML is a two-phase regimen of intensive chemotherapy (CTx) employing daunorubicin and cytarabine; etoposide may also be added in select regimens. Despite 60-70% of patients achieving complete remission (CR), …

Position- And Sex-Related Differences In Sagittal And Frontal Plane Concentric Isokinetic Hip Muscle Peak Torques And Agonist-Antagonist Ratios, Lisa T. Hoglund, Matthew C. Schiffino, James E. Freels, Isabella G. Romano

Department of Physical Therapy Faculty Papers

BACKGROUND: Hip muscle weakness is associated with many musculoskeletal conditions and athletic injuries. Isokinetic testing is often performed to measure a patient's strength or to assess treatment response. Patient sex and positioning during isokinetic strength testing may influence peak torque production and the agonist-antagonist peak torque ratios. However, different test positions are used clinically and in research to measure hip muscle strength. It is unknown how patient test position or sex impacts test results.

HYPOTHESIS/PURPOSE: The purpose of this study was to determine whether concentric isokinetic peak torques of sagittal and frontal plane hip muscles differ when tested in recumbent …

Protein Consumption And Risk Of Cvd Among Us Adults: The Multi-Ethnic Study Of Atherosclerosis (Mesa), Ji Yun Tark, Ruosha Li, Bing Yu, Alexis C Wood, Nikhil S Padhye, Marcia C De Oliveira Otto

Faculty, Staff and Students Publications

BACKGROUND: Although some randomized trials have reported beneficial effects of protein intake on cardiometabolic risk factors, evidence from prospective studies have not supported a strong link between protein intake and cardiovascular disease (CVD) risk. It is also unclear whether diversity in protein intake plays a role in CVD risk.

OBJECTIVE: We investigated prospective associations of (1) protein intake, overall and by food source and (2) diversity of protein sources with risk of CVD, coronary heart disease (CHD), and stroke.

METHODS: In a multi-ethnic cohort of 5879 U.S. adults (45-84 years), who were free of CVD at baseline, protein intake was …

Using Patient-Reported Experiences To Inform The Use Of Foam Dressings For Hard-To-Heal Wounds: Perspectives From A Wound Care Expert Panel, Kevin Woo, Nick Santamaria, Dimitri Beeckman, Paulo Alves, Breda Cullen, Amit Gefen, José Luis Lázaro-Martínez, Hadar Lev-Tov, Bijan Najafi, Andrew Sharpe, Terry Swanson

Center on Aging Staff Publications

Caring for patients with hard-to-heal (chronic) wounds requires a multifaceted approach that addresses their diverse needs, which can contribute to the complexity of care. Wound care providers must have a comprehensive understanding of the patient's comorbid conditions and psychosocial issues to provide personalised and effective treatment. Key quality indicators for effective wound care involves not only selecting appropriate local wound care products, such as foam dressings, but also addressing individual patient experiences of wound-related pain, odour, itch, excessive wound drainage, and self-care needs. The purpose of this review is to inculcate the wound care practice community, research scientists and healthcare …

Distinct Escherichia Coli Transcriptional Profiles In The Guts Of Recurrent Uti Sufferers Revealed By Pangenome Hybrid Selection, Mark G Young, Jesús Bazan Villicana, Philippe Azimzadeh, Andrew Kau, Karen W Dodson, Henry L Schreiber 4th, Scott J Hultgren, Et Al.

2020-Current year OA Pubs

Low-abundance members of microbial communities are difficult to study in their native habitats, including Escherichia coli, a minor but common inhabitant of the gastrointestinal tract, and key opportunistic pathogen of the urinary tract. While multi-omic analyses have detailed interactions between uropathogenic Escherichia coli (UPEC) and the bladder mediating urinary tract infection (UTI), little is known about UPEC in its pre-infection reservoir, the gastrointestinal tract, partly due to its low relative abundance (<1%). To sensitively explore the genomes and transcriptomes of diverse gut E. coli, we develop E. coli PanSelect, which uses probes designed to specifically capture E. coli's broad pangenome. We demonstrate its ability to enrich diverse E. coli by orders of magnitude, in a mock community and in human stool from a study investigating recurrent UTI (rUTI). Comparisons of transcriptomes between gut E. coli of women with and without history of rUTI suggest rUTI gut E. coli are responding to increased oxygen and nitrate, suggestive of mucosal inflammation, which may have implications for recurrent disease. E. coli PanSelect is well suited for investigations of in vivo E. coli biology in other low-abundance environments, and the framework described here has broad applicability to other diverse, low-abundance organisms.

Peptide Receptor Radionuclide Therapy And Clinical Associations With Renal And Hematological Toxicities And Survival In Patients With Neuroendocrine Tumors: An Analysis From Two U.S. Medical Centers, Tao Xu, Joseph S. Dillon, Mary A. Maluccio, Dawn E. Quelle, Sarah H. Nash, Hyunkeun Cho, Kristen E. Limbach, Nicholas J. Skill, Yvette Bren-Mattison, Michael A. O’Rorke

School of Medicine Faculty Publications

Purpose: Renal and hematological toxicity are side effects and dose-limiting factors of Peptide Receptor Radionuclide Therapy (PRRT). We aimed to assess the changes in renal and hematological function and associations with survival in neuroendocrine tumor (NET) patients treated with PRRT. Methods: A retrospective cohort of 448 NET patients treated with either 177Lu-DOTATATE or 90Y-DOTATOC were followed for changes of renal and hematological function. Renal function was assessed by monitoring changes in serum creatinine, blood urea nitrogen and estimated glomerular filtration rate. Hematological function was determined by examining changes in white blood cell counts (WBC), platelet counts, and hemoglobin levels over …

Input Of Sex Data Does Not Affect Metabolic Variables Returned From The Cosmed K5 Unit During Exercise, Olivia R. Perez, Michael W.H Wong, Dustin W. Davis, James W. Navalta

International Journal of Exercise Science: Conference Proceedings

There is a sex-data gap in sport and exercise, which results in an underrepresentation of female participants and increases the possibility of misgendering individuals who identify other than the female-male binary. A potential barrier to gender inclusivity could be that common exercise science equipment and software are limited to binary options for sex, excluding people who identify as gender minorities. PURPOSE: The purpose of this study was to evaluate whether sex data input into the COSMED K5 had a direct effect on metabolic outcome variables. METHODS: Seven adult participants (age = 29.6 ± 10.8 years, height = 172.6 ± 8.5 …

The Effects Of Music On Force Production, Pleasure, Perceived Exertion, Fatigue, And Recovery During An Isokinetic Strength Task, Ainsley Nommensen, Leighton Jones, Zachary Zenko

International Journal of Exercise Science: Conference Proceedings

Music is frequently listened to during exercise to enhance the overall experience. Prior research suggests promising effects of music for enhancing pleasure experienced during exercise, reducing perceived exertion, reducing fatigue, and enhancing recovery. PURPOSE: The purpose of this study was to offer new insights into how self-selected music can impact affective responses, perceptions of exertion and fatigue, and performance on a resistance exercise task. METHODS: A total of 34 participants (21 women and 13 men, mean age: 22 ± 6 years) completed two sessions of isokinetic resistance exercise in a counterbalanced order. In the experimental session, participants listened …

Erα Governs The Sexual Dimorphism In Hsp72-Mediated Control Of Mitochondrial Function, Exercise Capacity, And Insulin Sensitivity In Mice, Noelle Morrow, Amanda Lin, Zhenqi Zhou, Hirotaka Iwasaki, Brian Drew, Mark Febbraio, Andrea Hevener

International Journal of Exercise Science: Conference Proceedings

HSP72 is a chaperone protein upregulated during exercise. Levels are reduced in aging and obesity, and increased levels are correlated with improvements in metabolic health in male mice and humans. Male HSP72KO mice have increased body fat, decreased insulin sensitivity, and a loss of mitochondrial quality control. Specifically, male KO mice have increased cytosolic Parkin levels, but the protein is unable to move to the mitochondria resulting in enlarged, hyperfused mitochondria associated with metabolic dysfunction. PURPOSE: To investigate the role of HSP72 in female mice to better understand the sexual dimorphism involved in the heat shock response. METHODS: …

Lower Extremity Muscle Volume As A Prediction For Sprint Speed In Collegiate Football Players, Malorie Wilwand, Joshua Sponbeck, Steven P. Allen, Greg Snow, Iain Hunter, Aaron W. Johnson

International Journal of Exercise Science: Conference Proceedings

Sprinting is a crucial component of success in American football regardless of the position group. PURPOSE: To evaluate the relationship between muscle volume (MV) of the lower body muscles and sprint performance among different AF position groups. METHODS: This was a secondary analysis from the HAMIR study. The study included NCAA Division I AF players aged 18 and older who were active on the roster and not injured at the time of data collection. Positions were grouped as follows: the combo group (linebackers and tight ends), the big group (offensive and defensive linemen), and the skill group (defensive …

Influence Of Fitness On Moderate-Intensity Blood Pressure Responses In Normotensive And Hypertensive Individuals, Joseph Larsen, Jayson Gifford

International Journal of Exercise Science: Conference Proceedings

Early detection and treatment is important in cardiovascular disease because arteries are often occluded by 75% or more before symptoms become apparent. Exercise blood pressure has been shown to be predictive of future cardiovascular disease independent of resting blood pressure. However, many factors affecting exercise blood pressure need to be further investigated and described before exercise blood pressure can become a common practice. PURPOSE: To investigate how exercise intensity and fitness influence the blood pressure response in hypertensive and normotensive individuals. We hypothesized that hypertensive participants would have greater increases in exercise blood pressure than normotensive subjects during a …

Football Player Achilles Tendon Size Decreases Following Lower Body Strengthening Exercises With An Observed Increase In Blood Flow To The Tendon, Jeffrey J. Stewart, Lee J Hinkle, Austin Goodrich, Malorie Wilwand, Gabe Davidson, Bryson T. Schaugaard, B. Brett Mortensen, Matthew K. Seeley, A. Wayne Johnson

International Journal of Exercise Science: Conference Proceedings

ABSTRACT

The loading forces experienced during exercise may cause morphological and vascularization changes in the Achilles tendon. The Achilles tendons of runners decrease in cross-sectional area (CSA) after a distance run. Understanding acute morphological changes as a result of single bouts of exercise gives insight to clinicians about how to organize and recommend training sessions and recovery and may inform injury risk. Purpose: This study aims to characterize changes in tendon thickness, CSA, and blood flow of Division I collegiate football (FB) players before and after a bout of strengthening exercise. Methods: Twenty-nine participants (height: 189±5.62 cm, weight: 106±19.0 kg, …

Effect Of Caffeine On Symptoms And Biomarkers Of Gastrointestinal Injury After Physical Work In The Heat, Marissa Ramirez, Jonathan Specht, Fabiano Amorim

International Journal of Exercise Science: Conference Proceedings

Effect of Caffeine on Symptoms and Biomarkers of Gastrointestinal Injury After Physical Work in the Heat

MARISSA RAMIREZ, JONATHAN W. SPECHT, FABIANO T. AMORIM

Exercise Science Laboratory; Department of Health, Exercise, and Sport Sciences; University of New Mexico; Albuquerque, NEW MEXICO

Category: Doctoral

Advisor / Mentor: Amorim, Fabiano ([email protected])

ABSTRACT

Several job industries require substantial prolonged physical exertion in hot environmental conditions which increases the risk of heat-related illnesses. Endotoxemia, a hallmark of exertional heat stroke, is defined by increased levels of circulating lipopolysaccharides, often caused by gastrointestinal (GI) injury and subsequent permeability. Caffeine is a stimulant frequently used among …

Proceedings From The Fifth Annual For Society For Sports Neuroscience Conference, Neurosports Editorial Staff

Journal for Sports Neuroscience

Proceedings from the Fifth Annual for Society for Sports Neuroscience Conference

Applying Efficiency To Quantify Workplace Violence Situations For Meaningful Analysis, Erika Whetstone Msn, Rn, Cphq

Nursing Publications, Posters, & Presentations

Presented at the 2024 Parkview Nursing Research Symposium.

Background/Problem: Standard data gathering around workplace violence has been a national gap and there is not a national recommendation on how or what data points to collect. Purpose: A process was developed that enabled automated data collection and aggregation which allowed gathering of workplace violence data. The process built moved from a manual time-consuming endeavor to an efficient process that quantified a multitude of key metrics needed for analysis that can be used to drive meaningful mitigation. Methods: A focus study was built within Midas that included most of the elements from …

Decreasing Healthcare Associated Infections (Hais) With Pre-Shift Chlorohexidine Gluconate (Chg) Handwashing. Does It Work?, Mackenzie Spangler Bsn, Rn, Ocn, Julie Roth Bsn, Rn

Nursing Publications, Posters, & Presentations

Presented at the 2024 Nursing Research Symposium.

Background: HAIs are a concern for all healthcare organizations. Implementing preventative measures to minimize these occurrences become paramount within nursing practice. CHG is a common antimicrobial solution used throughout healthcare to decrease colonization on patients, but there is also data suggesting that staff performing CHG handwashing prior to a shift as an additional layer of prevention. Purpose: The purpose of this EBP project was to determine if the addition of CHG hand hygiene prior to starting the bedside shift was superior when compared to hand hygiene standards including alcohol-based sanitizer and regular soap …

Evaluating Stress Relief Management Through Use Of Candy On An Orthopedic Trauma Unit, Kelsi Cantrell Bsn, Rn

Nursing Publications, Posters, & Presentations

Presented at the 2024 Parkview Nursing Research Symposium.

Background : Questioned the evidence and opportunity for simple strategies to reduce in-the-moment clinical staff anxiety or stress. Came across a popular therapy trend in which sour or spicy candy is used as a form of distraction for momentary panic-level anxiety. With help from the Parkview Librarian, discovered there was not much information to support this theory, but also that it may not have been evaluated in the context of in-patient, clinical staff stress. Initiated “Stress Relief Treats” project on the Orthopedic Trauma unit in June 2024 to assess if pausing to …

Birth By Land Or By Water: Implementing Waterbirth At Parkview Randallia, Kim Noga Msn, Rn, Rnc-Mnn, Ibclc, C-Efm, Allison Thorpe Mba, Msn, Cnm, Nataley Frane Bsn, Rn, Sarah Pickens Bsn, Rn, Lisa Smith Msn, Rn, Agcns-Bc, Np-C, Rnc-Ob, Angela Russ Russ Msn, Rn, Rnc-Mnn, Ibclc

Nursing Publications, Posters, & Presentations

Presented at the 2024 Parkview Nursing Research Symposium.

Background: Childbirth is a natural physiologic event, with most women requiring some form of pain relief during their birth experience. The transition of Parkview’s Certified Nurse Midwife Program to Parkview Randallia’s Family Birthing Center in the fall of 2023 increased the demand for non-pharmacologic labor and birth options for low-risk pregnant patients. One option for non-pharmacologic pain relief is water immersion and waterbirth. Water immersion during labor and waterbirth can promote comfort and reduce the need for medical interventions during labor. There is currently no option for women to achieve a waterbirth …

A Scoping Review: Multimodal Pain Management To Reduce Perioperative Opioid Use In Total Knee Arthroplasty, Renee Merrill, Curt C. Stilp, Shane Merrill, Michelle Rhea, Jason Brumitt

Doctor of Medical Science (DMSc)

Background: The opioid epidemic ranks among the most significant public health crises of our time, with prolonged opioid use often resulting from overprescription following surgeries such as total knee arthroplasty.

Methods: PubMed and Medline (EBSCO) were searched from inception until July 2024 for studies comparing multimodal pain management interventions aimed at reducing opioid use after total knee arthroplasty (TKA) to a control group. Twenty-eight articles were identified that met the inclusion criteria.

Results: Opioid-sparing multimodal pain management approaches, including acetaminophen, non-steroidal anti-inflammatory drugs, cyclooxygenase-2 inhibitors, gabapentinoids, peripheral nerve blocks, cryoneurolysis and local infiltration analgesia, can effectively manage pain after a …

Encouraging Movement Opportunities Through Theory-Informed Video Education Among Undergraduate Students: The Move Study, Carmen Labadie, Nia Contini, Varsha Vasudevan, Matthew Bourke, Shauna Burke, Patricia Tucker, Jennifer Irwin

Health Studies Publications

Objective: To explore the impact of a theory-informed educational video on undergraduates’: motivational readiness, self-efficacy, and decisional balance about changing sedentary time; sedentary time; and perceptions of sedentarism over time and compared to a control. Participants: Undergraduates (N = 160) from a Canadian institution. Methods: A single-blind randomized controlled trial using an intervention (sedentary video) and control (sleep video) group. Participants completed two validated questionnaires at baseline, immediate post-intervention, and one-month follow-up plus open-ended questions. Linear mixed models and content analysis were used. Results: No significant differences were observed between groups. Increases in self-efficacy (p = .016; d = 0.27) …

General Practice Training In Australia: National Report On The 2024 National Registrar Survey, Rebecca Taylor, Leyna Clarke, Michelle Hsien, Ali Radloff

Higher education research

The General Practice National Registrar Survey (GP NRS) is an annual, national survey of GP registrars currently training in Commonwealth funded trainings programs which include Australian General Practice Training (AGPT), Remote Vocational Training Scheme (RVTS) and Rural Generalist Training Scheme (RGTS) programs (prior to 2024, it was only carried out with AGPT registrars). It collects information via an online questionnaire about GP registrar satisfaction, experience and future career plans. It also collects information about GP registrars’ demographics and training contexts and other aspects of their training experience. This survey is part of the Department of Health and Aged Care’s (the …

Musical Hallucinations In An Elderly Female With Hearing Loss, Jacqueline Cavendish, Lynne J. Goebel

Internal Medicine

Musical hallucinations (MH) are rare auditory phenomena in which patients perceive music without a known source. Risk factors for MH include hearing loss, older age, female gender, epilepsy, and certain medications. This case report details the presentation, diagnosis, and treatment of an 82-year-old woman who developed MH following the onset of hearing loss. Despite treatment attempts with gabapentin, quetiapine, and donepezil, the symptoms persisted, demonstrating the difficulty in treating this condition.

Mccormack, Joseph Nathaniel, 1847-1922 And Arthur Thomas Mccormack, 1872-1943, Manuscripts & Folklife Archives

Manuscript Collection Finding Aids

Finding aid and scans (Click on "Additional Files" below) for Manuscripts Small Collection 3738. Arrest warrants issued by the Bowling Green, Kentucky Police Court charging Dr. J. N. McCormack, then Secretary of the State Board of Health, and Dr. A. T. McCormack with permitting a “nuisance, source of filth & cause of sickness” by erecting a privy over an open drain or sewer to serve the McCormack Building on State Street. Includes a letter, 29 September 1907, from Dr. J. N. McCormack to Governor J. C. W. Beckham requesting a pardon and describing his ongoing efforts to dispose of waste …

Thoughts From The Frontline - November 2024, Tennessee Center For Nursing Advancement, East Tennessee State University

Thoughts from the Frontline Newsletter

No abstract provided.