Medicine and Health Sciences Commons^™

Children And Young People's Self-Reported Experiences Of Asthma And Self-Management Nursing Strategies: An Integrative Review, H. Kemble, Mandie Foster, J. Blamires, R. Mowat

Research outputs 2022 to 2026

Aim: To explore children and young people's (CYP) (5–24 years of age) self-reported experiences of asthma self-management strategies (ASMS) with nursing involvement across various settings. Background: Childhood asthma is an increasingly significant health issue, highlighting the importance of acquiring self-management skills to optimise future health outcomes. Registered nurses play a pivotal role in delivering appropriate, personalized self-management support. Methods: This integrative review searched four electronic databases: Cumulated Index to Nursing and Allied Health Literature via Elton B. Stephens Company, Medical Literature Analysis and Retrieval System Online (MEDLINE), Object, View and Interactive Design (OVID), and PubMed, that followed the Preferred Reporting …

An Examination Of The Career Decision-Making Self-Efficacy Of Final-Year Nursing Students, Edah Anyango, Esther Adama, Janie Brown, Irene Ngune

Research outputs 2022 to 2026

Background: One in four newly graduated registered nurses leave their employment positions within the first year. To reduce this attrition, nursing stakeholders could focus on the final year of nursing education because students at this stage make professional career plans, including their practice destination for the graduate year and their commitment to the profession. Previous studies provide evidence of nursing students' career preferences and specialty choices. However, there is a dearth of data that focuses on the students' career decision-making process. Aim: This study examined the self-efficacy or confidence of final-year nursing students in making career decisions and the factors …

Perceived Barriers And Enablers To Utilising The Australian National Disability Insurance Scheme For Adults With An Intellectual Disability And Their Families: A Scoping Review, Alice Zubrinich, Gideon De Jong, Nasim Salehi, Richard Lakeman

Research outputs 2022 to 2026

Background: The introduction of the National Disability Insurance Scheme (NDIS) in Australia in 2013 promised significant improvements in the lives of adults with intellectual disabilities. Although the scheme enables support, there are challenges associated with establishing eligibility and administering funds. This scoping review explored perceived barriers and enablers to effectively utilising the NDIS for adults with intellectual disabilities and their families. Method: A scoping review of the empirical literature on the NDIS and intellectual disabilities included nine studies in this review. These papers were subjected to thematic analysis and the findings were presented as a narrative synthesis. Results: The key …

The Experiences And Perceptions Of Healthy Siblings Of Children With A Long-Term Condition: Umbrella Review, Julie Blamires, Mandie Foster, Shayne Rasmussen, Maggie Zgambo, Evalotte Mörelius

Research outputs 2022 to 2026

Problem: The lives of healthy siblings living with a sibling with a long- term condition are often shaped by the family, type of illness, length of illness, age of the child, caregiver demands, and support provided to the family, ill sibling, and healthy sibling. While the experiences of healthy siblings are documented in the literature by parent proxy, literature on healthy siblings self-reported experiences of living with a sibling who has a long-term condition remains scarce. Purpose: This umbrella review aims to synthesize reviews on the self-reported experiences of healthy siblings of children living with a sibling who has a …

Premenstrual Dysmorphic Disorder/Premenstrual Syndrome Luteal Phase Treatment, Shelby Gawarecki

Physician Assistant Scholarly Project Posters

• PMS/PMDD symptoms affect many women's emotional and physical wellbeing.

• SSRIs, progesterone, and sepranolone are luteal phase treatment options.

• Studies were all peer-reviewed, including randomized control trials or a meta-analysis.

• SSRIs are a consistent primary treatment for symptom alleviation especially cognitive symptoms. SSRIs are the current mainstay, recommended for luteal phase treatment of PMS/PMDD.

• SSRIs, including citalopram, sertraline, escitalopram, and fluoxetine, were examined to determine their efficacy in relieving mood-related symptoms such as irritability, anxiety, and depression during the luteal phase.

• Data on progesterone treatment in the luteal phase is inconclusive. • Allopregnanolone levels and …

Comparing The Efficacy Of Heart-Conserving Measures And Retransplantation For Chronic Rejection In The Pediatric Population, Lacey Zeiszler

Physician Assistant Scholarly Project Posters

Coronary allograft vasculopathy is the leading cause of morbidity and mortality among pediatric heart transplant recipients and faces unsuccessful treatment for prevention and management. Post-transplant immunosuppressive therapy has been modified over the years to determine the most effective regimen for rejection. Tacrolimus has been the superior immunosuppressant used for rejection since the early 2000s. It has been shown to have substantial immunosuppressive effects, least number of adverse effects, and decreased comorbidities compared to other regimens. Despite these advantages, CAV is still prevalent. Heart retransplantation is currently the only curative treatment. We used Google Scholar, PubMed, ClinicalKey, ScienceDirect, Elsevier, Wiley Online …

Genetic Correlations Between Liver Fat Content, Metabolic Health, And Adiposity Distribution In The Fels Longitudinal Study, Ariana L. Garza, Miryoung Lee, John Blangero, Cici X. Bauer, Stefan A. Czerwinski, Audrey C. Choh

School of Medicine Publications and Presentations

Highlights

• Steatosis and all other related phenotypes examined were significantly heritable.

• Liver fat showed significant genetic correlation with various phenotypes.

• The strongest genetic correlation of liver fat was with insulin resistance.

• Glucose homeostasis phenotypes were also genetically correlated to adiposity traits.

Abstract

Background and aims

Hepatic steatosis is known to be heritable, but its genetic basis is mostly uncharacterized. Steatosis is associated with metabolic and adiposity features; recent studies hypothesize that shared genetic effects between these traits could account for some of the unexplained heritability. This study aimed to quantify these genetic associations in a family-based sample of non-Hispanic white …

Perbedaan Pengaruh Media Edukasi Terhadap Kepatuhan Orang Tua Anak Cerebral Palsy Untuk Melaksanakan Home Program, Khabib Abdullah, Ichsanul Amalia, Aji Sukma Wijaya

Jurnal Fisioterapi Terapan Indonesia or Indonesian Journal of Applied Physiotherapy

Cerebral palsy (CP) is a condition of movement and function disorders in children that requires continuous physiotherapy. One factor in the successful development of children with CP is the existence of a home program/independent therapy carried out by parents at home. In providing the home program, physiotherapists at YPCP Surabaya gave leaflets to parents. However, this was less effective because it was easily damaged, so the home program media was replaced with video. The effectiveness of both in increasing parental compliance in carrying out the home program every day is not yet known. Objective: to find out the difference in …

Severe Vitamin B12 Deficiency Presenting With Pseudo-Thrombotic Microangiopathy And Anasarca, Aleksandra Kolnick, Polly Fraga, Jing-Lun James Xu, Muhammad Awidi

The Lahey Journal

Introduction

This report describes the case of a woman with severe vitamin B12 deficiency from pernicious anemia. Her clinical presentation, which involved microangiopathic hemolytic anemia (MAHA), was presumed to be thrombotic thrombocytopenic purpura (TTP). TTP is a rare life-threatening condition with high mortality and morbidity rates. It is caused by a severe deficiency of ADAMTS13, an enzyme which cleaves the von Willebrand factor in the clotting cascade. This case report highlights the importance of early recognition of TTP and other causes of MAHA. We explore the pathogenesis and management of severe, life-threatening vitamin B12 deficiency.

Case Presentation

A 51-year-old woman …

What Are The Lessons Learned From A Survivorship Trial During The Pandemic?, Alanna Horowitz, Sharneet Sandhu, Sherry Guo, Gabriel Barreto-D'Silva, Leonardo Barreto-D'Silva, Krishna Gunturu

The Lahey Journal

Purpose: The American Cancer Society (ACS) has acknowledged the importance of maintaining a healthy diet and engaging in regular physical activity for cancer survivors. While studies have found that adherence to these guidelines improves long-term quality of life, several studies showed that up to 70% of cancer survivors do not meet the standards. The purpose of this pilot study is to determine the effectiveness of a multi-disciplinary survivorship clinic (MDSC) in helping patients adhere to the ACS survivorship guidelines and its impacts on quality of life (QOL).

Methods: Primary objective of the study is to encourage cancer patients to adhere …

Effects Of A 10-Week Footstrike Transition Programme On Tibial Stress Fracture Probability; A Randomized Controlled Intervention Using Finite Element And Probabilistic Modelling., Jonathan Sinclair, Paul J. Taylor

Baltic Journal of Health and Physical Activity

Introduction: The aim of this study was to undertake a randomized control trial examining the effects of a 10-week footstrike transition program on tibial stress fracture risk compared to control. Material and methods: Twenty habitual rearfoot strike runners were randomly assigned to either footstrike or control groups. The footstrike group undertook a graduated 10-week program which allowed them to convert their habitual rearfoot strike pattern, whereas the control group maintained their normal training regime without any alterations to their strike pattern. Running biomechanics were collected using an eight-camera motion capture system, and ground reaction forces using a force plate. Tibial …

Evaluation Of Elevation Parameter Determination By Global Navigation Satellite Systems’ Sports Receivers: A Preliminary Study, Tomasz Szot, Marcin Sontowski

Baltic Journal of Health and Physical Activity

Introduction: Sports Global Navigation Satellite Systems’ receivers have been providing athletes, coaches, and scientists with valuable information on movement for over two decades. As these receivers are specific measuring instruments, there is a need to determine their accuracy. This paper presents a relatively simple methodology for assessing sports receivers of this type regarding their elevation determination. Material and methods: The methodology was based on the Digital Terrain Model of Poland, a discrete representation of the topographic elevation of the land surface. Three wearable devices from different years of manufacture were selected for the preliminary study by calculating the Root Mean …

The Evolution Of Body Posture In The Sagittal Plane In The Sensitive Growth Period Of Children And Adolescents Undergoing Individual Scoliosis Therapy: A Pilot Study, Barbara Rosołek, Katarzyna Smółka, Diana Celebańska, Monika Szarajew, Anna Zwierzchowska

Baltic Journal of Health and Physical Activity

Introduction: The shape of the spine in the sagittal plane undergoes evolution, which occurs specifically in children and adolescents with idiopathic scoliosis (IS). The aim of the study was to verify the variability of body features and indicators in relation to the features and parameters of body posture in children and adolescents with IS. Materials and Methods: 61 measurements of children and adolescents (three age groups) with IS were collected. Body height, body weight, waist circumference, hip circumference, scoliosis major curve angle, thoracic kyphosis angle, lumbar lordosis angle, spine length, and pelvic tilt were measured. BMI and WHtR were calculated. …

Identifying Overdose Risk Factors For People Hospitalized With Injection Drug Use-Associated Infections In Maine, Melanie Mait, Kim Murray, Tania D. Strout, Kinna Thakarar

Journal of Maine Medical Center

Introduction: The overdose crisis continues to be a significant problem, particularly in rural states such as Maine. The objectives of this study were to: 1) describe demographic and health characteristics and 2) identify overdose risk factors among people in Maine hospitalized with injection drug use (IDU)-associated infections.

Methods: We performed descriptive analysis of demographics, health characteristics, and injection practices, stratified by lifetime history of overdose. We conducted an exploratory logistic regression analysis, controlling for gender, homelessness, having experienced an emergency department (ED) visit in the past 3-months, and endorsement of injecting alone in the past 30 days to examine …

Let’S Go! 2022-2023 Educational Programs: Developing A Standardized Obesity Medicine Curriculum Through A Realist Evaluation, Isaac Stickney, Peter Amann, Victoria Rogers, Austin Steward, Kayla Bronzo, Alec Luro, Robert Bing-You

Journal of Maine Medical Center

Problem: Obesity is linked to more than 200 chronic conditions, lower quality of life, and worse outcomes for patients. Let’s Go! is a community engagement initiative that works with communities to create environments that support healthy behaviors that impact obesity. Let’s Go! provides educational programming for all medical learners and providers throughout Maine and Carroll County, New Hampshire. The goal of Let’s Go! is to address the health outcomes of obesity and the stigma associated with it, including its impact on patients’ mental health and clinicians’ unconscious biases.

Approach: We used a realist evaluation, a framework in which the social …

Intravenous Iron In Patients Hospitalized With Bacterial Infections: Utilization And Outcomes, Nicolette Centanni, Jennifer Hammond, Joshua Carver, Wendy Craig, Stephanie Nichols

Journal of Maine Medical Center

Introduction: Given the uncertainties with IV iron therapy and potential risk of infection, there may be hesitation to treat hospitalized patients with bacterial infections with this preparation even if clinically indicated. The aim of this study was to examine patterns of prescribing IV iron in hospitalized patients being treated for a bacterial infection and associated clinical outcomes in those with severe infections.

Methods: This retrospective chart review evaluated adult patients who received both IV iron sucrose and antibiotics during the same admission at Maine Medical Center during 2019. Data collected included iron studies and IV iron prescribing practices. Clinical outcomes …

Evolution Of Global Anatomy Research Through Covid-19: A Post-Pandemic Evaluation, Harsh Chheda, Santanu De

FDLA Journal

The Coronavirus Infectious Disease 2019 (COVID-19) struck the world with a deep impact on many countries' healthcare systems. More specifically, anatomical research experienced a drastic setback due to the limitations and restrictions placed upon them by the medical community. This study aims to review how COVID-19 guidelines presented conflict regarding the retrieval and use of cadavers, as well as how anatomy research was modified on a global scale owing to the pandemic. The COVID-19 outbreak called for several changes upon each significant anatomical research technique, ranging from cadaver dissection to diagnostic imaging. Given the remarkable shift in medical research guidelines …

The Future Of Nursing Leadership: Incorporating E-Learned Artificial Intelligence (Ai) Pathways With A Precautionary Focus On Patient-Centered-Care, Jamie Anne Marcus Dr., Bonnette Villalba Webb

FDLA Journal

Artificial Intelligence (AI) is a data-driven mathematical process that incorporates machine-based-logic, usually in the form of algorithms. Education, training, and competencies are now conducted through virtual reality, robotics, simulation, and technology learning-based-platforms by healthcare organizations. This represents a significant change in the future of nursing practice. The adaptability of technology-based-learning platforms can impact the quality and efficiency of learning for some of the workforce population. Nurses' perception of technology and AI-driven nursing practice may vary based on generational orientation and can be a potential barrier to learning, practicing, and adaptability of this framework. The forging of well-trained resilient nurse leaders …

Global Implications Of Covid-19 On Education And Research In Healthcare And Stem: Analysis Of Case Studies, Yumna Indorewala, Santanu De

FDLA Journal

The zoonotic novel coronavirus, SARS-CoV-2 posed major threats to the world’s economy, social development, and public health. Education and research in STEM and healthcare were no exceptions to the global implications of the Coronavirus Infectious Disease 2019 (COVID-19) pandemic. Social distancing guidelines were initially recommended to refrain from in-person operations for preventing the transmission of the virus. As academic organizations implemented multifarious methods to effectively transition to remote/online or hybrid educational formats, COVID-19 necessitated designing, adopting, as well as evaluating the efficacy of new instructional approaches, especially for disciplines that require active, experiential learning such as healthcare and STEM. These …

Proceedings Of The Cuny Games Conference 10.0, Robert O. Duncan, Grace Axler-Diperte, Joe Bisz, Christina Boyle, Devorah Kletenik, Carolyn Stallard

Publications and Research

The ten-year anniversary (!) of the CUNY Games Conference combines workshops, idea exchanges, interactive participant presentations, playtesting, and playing tabletop games into a two-day hybrid event to promote and discuss game-based learning. The conference focuses on creative pedagogy, such as playful learning activities or games, that teachers can use in the classroom every day. Day 1 featured interactive presentations by attendees, informal idea exchange sessions, and workshops by the conference organizers. Day 2 featured select presentations and workshops, poster sessions, playtesting and game modding, and casual play of tabletop games.

The Health Risks Of Deportation: Impacts Of Family Separation On Relationships And Wellbeing In Latinx Communities, Shantay Rocha

University Honors Theses

Anti-immigration policy and deportation practices create multifaceted implications for Latinx communities in the United States. A comprehensive literature review drawing from public health and immigration studies was used to examine the direct and indirect implications of separation of families due to deportation. This thesis synthesizes existing research to illuminate the health threats pertaining to Latinx wellbeing in the context of being undocumented and fearing being separated from their family. Addressing the dimensions of deportation-related health risks, policy makers, health care professionals, and community organizations can work towards promoting Latinx health and well-being in the U.S. to mitigate the health consequences …

Evaluation Of Sleep Outcomes After Traumatic Brain Injury In Children Using Questionnaires And Actigraphy, Connie Tran

University Honors Theses

Traumatic brain injuries are the result of a sudden external blunt force to the brain and can result in long-term complications or death. In pediatrics, it is the leading cause of acute and chronic sleep-wake disturbances, as well as cognitive deficits, which can lead to a reduction in the quality of life for these children. These impairments can later result in lowered performance in work and school settings or decreased psychosocial function. Currently, there is a need to determine the relationship between traumatic brain injury (TBI) and sleep. There is a need for more research on whether or not sleep-wake …

Biophilic Design Strategies In Healthcare: Using Nature To Promote Wellness In Small-Scale Mental And Behavioral Health Facilities, Skyler Peckham

University Honors Theses

Designing spaces that promote the health and well-being of the general public has been a highly debated topic for several centuries within the disciplines of architecture, urban planning, and other similar fields. As more research has been done throughout the years, the notion of utilizing nature to promote wellness has become a prominent design strategy. Through the examination of a wide range of scholarship regarding the benefits that nature has for human health and connecting this research to the biophilic evidence-based design strategies of healthcare facilities, I aim to highlight what design aspects truly promote wellness for patients in small-scale …

Compassionate Practice: A Review And Framework For Integrating Medical Humanities Into Pre-Medical And Medical Curricula, Megan E. Mccoy

University Honors Theses

The article presents the findings of a comprehensive narrative literature review aimed at addressing the question: What are the current frameworks of the medical humanities discipline in terms of purpose, methodology, curriculum, and student learning outcomes? Thematic analysis and qualitative coding highlighted key themes and areas of concern, including the purpose of medical humanities, methodology, current curriculum, and student outcomes. Recommendations are provided to address disagreements within the discipline, proposing a conceptual framework and definition for medical humanities, alongside advocating for a mixed-method approach as the primary methodology. Curriculum guidelines emphasize the importance of a quality integrated curriculum focusing on …

The Cost Of Healthy Eating, Diana Prychyna

University Honors Theses

Background

Each year in the United States, 15-20% of 1 million visits to the Emergency Department for Acute Heart Failure result in home discharge, with patients often experiencing adverse health outcomes within 30 days. The study, Get With the Guidelines in Emergency Department Patients With Heart Failure, utilized ‘Self-Care Coaches’ who meet participants via telehealth calls to discuss self-care maintenance after discharge as a strategy to mitigate adverse health outcomes; and offer provisions of resources, including a cookbook by the American Association for Heart Failure Nurses (AAHFN).

During telehealth calls, we observed gaps in self-care for retired older adults (62+), …

Health Equity In Stroke Prophylaxis For New Atrial Fibrillation In The Emergency Department, Mariam Anwar

University Honors Theses

Study Objective: Atrial fibrillation (AF) is the most common cardiac arrhythmia, and often, first diagnosed in the emergency department (ED). AF increases the risk of stroke, which can be decreased by 64% if the appropriate oral anticoagulation (OAC) is prescribed. However, many patients are not prescribed OAC for new AF. We investigate whether patient ethnicity, specifically Hispanic-Latino & Russian/Ukrainian, affects OAC prescription.

Method: This retrospective chart review study included patients at an academic tertiary care center and a community hospital >17 years old with a primary ED diagnosis of AF or paroxysmal AF from January 2020-2024. Patients with valvular heart …

Biofeedback Gaming For Substance Use Disorder, Rebecca L. Chevrel

University Honors Theses

Substance Use Disorder (SUD) and stress are often predictive of one another, bidirectionally causal, and mutually intensifying. This thesis describes the bi-directional connection between physiological stress-modulating systems and Substance Use Disorder, and explores some emerging biofeedback stress-reduction gaming technology as a potential adjunct to recovery treatments. Improving autonomic balance, often described by Heart Rate Variability, has been shown to be beneficial for physical and psychological recovery, as well as improving self-control. For this reason, regular biofeedback for stress relief could be helpful in augmenting SUD treatment and preventing relapse. This exploration found that presenting it through a gaming lens may …

Colocalization Of Odc And Amyloid Plaques In Patients With Alzheimer’S Disease And Down Syndrome, Julia S. Gielczynski

Undergraduate Theses, Capstones, and Recitals

Polyamines, and their rate-limiting enzyme ornithine decarboxylase (ODC), are crucial for many functions in the central nervous system but levels decrease with age. In neurodegenerative diseases, like Alzheimer’s Disease (AD), polyamine levels begin to increase again. Yet, there are still many unanswered questions surrounding polyamine’s possible role in AD, especially in those with Down Syndrome (DS), who also have an extra copy of the amyloid precursor protein (APP) and tend to get AD far earlier than the general population. We aim to investigate if there is colocalization between amyloid plaques and Ornithine Decarboxylase (ODC) in patients with AD and AD/DS, …

Investigating The Role Of Ebf3a In Craniofacial Development, Shujan A. Sharafeldeen

Undergraduate Theses, Capstones, and Recitals

Proper craniofacial development requires many genes. Single-cell RNA sequencing (scRNA-seq) allows us to identify genes expressed in precursor cells for craniofacial structures, but the function of many of these genes in craniofacial development has yet to be characterized. In our scRNA-seq of cranial neural crest cells (NCCs), which are precursor cells for the craniofacial skeleton, we found a gene called early B-cell factor 3 (ebf3a) that may be involved in craniofacial development. In our scRNA-seq data, ebf3a expression is restricted to cranial NCCs of the dorsal and ventral domains of pharyngeal arches 1 and 2. In humans, damaging variants in …

Modificaciones Realizadas En Cirugías Y En Cuidados De Pacientes En Ecuador, Addison Wolfe

NEXUS: The Liberty Journal of Interdisciplinary Studies

No abstract provided.