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2024

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Articles 24151 - 24180 of 27153

Full-Text Articles in Medicine and Health Sciences

Adverse Childhood Experiences Increasing The Likelihood Of Substance Use Disorder, Kelsey L. Cain Jan 2024

Adverse Childhood Experiences Increasing The Likelihood Of Substance Use Disorder, Kelsey L. Cain

Graduate Research Papers

No abstract provided.


The Effects Of Alcohol Consumption On Cognitive Decline, Ashley Highland Jan 2024

The Effects Of Alcohol Consumption On Cognitive Decline, Ashley Highland

Graduate Research Papers

The purpose of this study was to examine the relationship between alcohol use and cognitive decline among young adults. This study is a quantitative study in which secondary data was used as a means to gather information from the 2022 Behavioral Risk Factor Surveillance System (BRFSS) database. In this study, the researcher analyzed the data using descriptive statistics and inferential statistics, such as independent sample t-test, correlations analysis, ANOVA, and Chi-Square test. The findings in this research revealed that there is a significant relationship between cognitive decline and binge drinking in young adults. Meaning, young adults who binge drink are …


Confronting Cte: A Blog Dedicated To Increasing Awareness In Chronic Traumatic Encephalopathy, Caden Shea Jan 2024

Confronting Cte: A Blog Dedicated To Increasing Awareness In Chronic Traumatic Encephalopathy, Caden Shea

Honors Program Theses

The variation on a creative thesis that I formed was a website and blog that utilized research about Chronic Traumatic Encephalopathy and how it affects athletes of all kinds, specifically athletes in the National Football League. The reason that I chose this topic is because the field that I hope to go into is that of sports journalism. One of the biggest problems facing sports leagues all over the world is the issue of safety. One of the biggest safety concerns in sports is that of head injuries, and one of the most prominent head injuries is CTE. I chose …


Near-Infrared Paired-Agent Imaging For In Vivo Quantification Of Receptor Occupancy In Tumor, Yichen Feng Jan 2024

Near-Infrared Paired-Agent Imaging For In Vivo Quantification Of Receptor Occupancy In Tumor, Yichen Feng

Dartmouth College Ph.D Dissertations

Accurate assessment of drug receptor occupancy (RO) holds significant importance in both drug development and personalized medicine, as it facilitates quantitative characterization of dose-response relationship for a given drug. This information not only aids appropriate dose selection for clinical trials but also guides personalized dose optimization in precision medicine.

Molecular imaging, utilizing receptor-specific imaging agents for tissue visualization, has emerged as the major option for in vivo measurement of tissue RO. Nonetheless, the abnormal yet complex structure and hemodynamics of tumors often lead to substantial non-specific uptake and retention of imaging agents, thus introducing significant bias to RO measurements. To …


Continuous, Platform Purification Of Viral Products Using Aqueous Two-Phase Extraction, Natalie M. Nold Jan 2024

Continuous, Platform Purification Of Viral Products Using Aqueous Two-Phase Extraction, Natalie M. Nold

Dissertations, Master's Theses and Master's Reports

Cell and gene therapies, a ground-breaking class of drugs that can heal genetic diseases and cure cancer, often have treatment costs over $1 million. Most cell and gene therapies are delivered using virus-based delivery vectors, which are incredibly expensive to manufacture. Liquid chromatography is the favored method of viral vector purification since it is easily scalable and can be functionalized to purify by biospecificity, charge, hydrophobicity, or size. However, chromatography-based purification processes are highly expensive and usually only recover 20-50% of the viral vectors. There is currently no platform purification strategy for viral vectors due to differences in their surface …


Autonomic Modulation Of Cardiac Function In Hypertrophic Cardiomyopathy, Jenna Rose Disser Jan 2024

Autonomic Modulation Of Cardiac Function In Hypertrophic Cardiomyopathy, Jenna Rose Disser

Dissertations, Master's Theses and Master's Reports

Hypertrophic cardiomyopathy (HCM) is the most common genetic heart disorder. HCM is characterized by cardiac hypertrophy, fibrosis, and an increased risk of fatal arrhythmias and sudden cardiac death. Previous studies in humans with HCM have demonstrated increased cardiac norepinephrine spillover and reduced beta-1 receptor (β1R) expression in the left ventricle (LV). We have previously demonstrated that cardiac sympathetic tone is elevated in an alpha-tropomyosin mutant mouse model of HCM. We hypothesized that HCM mice would demonstrate reduced β1R expression in the LV and attenuated heart rate (HR) and dP/dt max responses to ramped infusion of the β1R agonist, dobutamine. …


Computational Analysis Of Vascular Aneurysms, Seyedmostafa Rezaeitaleshmahalleh Jan 2024

Computational Analysis Of Vascular Aneurysms, Seyedmostafa Rezaeitaleshmahalleh

Dissertations, Master's Theses and Master's Reports

Vascular aneurysms, such as intracranial aneurysms (IAs) and abdominal aortic aneurysms (AAAs), pose significant health risks, particularly upon rupture. Disturbed hemodynamics, characterized by swirling flow patterns, can lead to cellular and structural changes that disrupt normal physiological processes and contribute to destructive vascular remodeling. Integrating hemodynamic analysis into clinical assessments of aneurysms has become crucial, especially through patient-specific computational fluid dynamics (CFD) simulations based on medical imaging. However, the complexity of CFD tools presents challenges in model creation and post-simulation analysis, limiting their accessibility to clinicians.
This project aimed to advance aneurysm management by exploring the role of intraluminal thrombus …


Energy Content Of Acorns Of Shinnery Oak (Quercus Havardii) In The Diet Of Scaled Quail (Callipepla Squamata) In Southeastern New Mexico, J.L. Hunt, M.E. Grilliot, T.L. Best, D. Lozano-Lopez, E.R. Neilson, I.C. Castillo Jan 2024

Energy Content Of Acorns Of Shinnery Oak (Quercus Havardii) In The Diet Of Scaled Quail (Callipepla Squamata) In Southeastern New Mexico, J.L. Hunt, M.E. Grilliot, T.L. Best, D. Lozano-Lopez, E.R. Neilson, I.C. Castillo

Journal of the Arkansas Academy of Science

Shinnery oak (Quercus havardii) is a deciduous, low-growing shrubby tree that is a dominant plant in large areas of grassland in western Oklahoma, the Texas Panhandle, and eastern New Mexico. Acorns of the plant are important food items for many wildlife species, including scaled quail (Callipepla squamata), mourning doves (Zenaida macroura), and endangered lesser prairie-chickens (Tympanuchus pallidicinctus). We analyzed the energy content of acorns of shinnery oak obtained from the crops of scaled quail collected from plains-mesa sand-scrub in Lea and Eddy counties, New Mexico. Acorns were removed from crops and dried for 48 hours at 60°C to remove moisture …


Challenges And Coping Strategies In Transitioning From Caregiving To Widowhood: A Systematic Review, Abby Baumbach, M. Courtney Hughes, Yujun Liu Jan 2024

Challenges And Coping Strategies In Transitioning From Caregiving To Widowhood: A Systematic Review, Abby Baumbach, M. Courtney Hughes, Yujun Liu

Faculty Articles, Papers, and Other Scholarship

Ninety-one percent of surviving spouses in the U.S. cared for their spouses before they died. This review explores the challenges of the transition from caregiving to widowhood and different coping strategies used by widowed spousal caregivers. A systematic review of literature on the transition from caregiving to widowhood was conducted using four major academic search engines. Overall, 280 articles were identified, with 22 meeting the inclusion criteria. Challenges for widowed caregivers included experiencing care burden, letting go of the caregiver role, grief, and triggers. Widowed caregivers’ coping strategies included social support and services use, filling the time gap, finding spirituality, …


Patient, Referring Physician, And Radiologist Opinions Over Time On Providing Patients Access To Radiology Reports: A Systematic Review, Mohammad Alarifi, M. Courtney Hughes, Abdulrahman M. Jabour, Yazeed Alashban, Erin Vernon Jan 2024

Patient, Referring Physician, And Radiologist Opinions Over Time On Providing Patients Access To Radiology Reports: A Systematic Review, Mohammad Alarifi, M. Courtney Hughes, Abdulrahman M. Jabour, Yazeed Alashban, Erin Vernon

Faculty Articles, Papers, and Other Scholarship

Objective: Patients increasingly have access to their radiology reports. This systematic review examined the opinions of patients, referring physicians, and radiologists over time on providing patients full access to their radiology reports.

Methods: A systematic review examining quantitative, qualitative, and mixed methods research using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines (PROSPERO CRD42023466502). Our search was conducted through September 30, 2023, and spanned five databases (CINAHL Plus, Web of Science, ProQuest, PubMed, and Scopus). The studies included were peer-reviewed journal articles about the opinions of patients, referring physicians, or radiologists regarding giving patients unrestricted access to their …


Assessing Life Expectancy Disparities In Chicago With A Deep Dive Into Green Space, Elizabeth J. Folkmann, M. Courtney Hughes, Lei Hua, Mohammad Alarifi, Mahdi Vaezi Jan 2024

Assessing Life Expectancy Disparities In Chicago With A Deep Dive Into Green Space, Elizabeth J. Folkmann, M. Courtney Hughes, Lei Hua, Mohammad Alarifi, Mahdi Vaezi

Faculty Articles, Papers, and Other Scholarship

Background

Few studies have examined the association between green space and life expectancy, and only one study has looked at that data for small areas in the United States. These studies have found a positive association between green space and life expectancy. This study investigates the association between green space and small-area life expectancy in Chicago, a city in the United States with distinct environmental and socioeconomic characteristics and the largest U.S. life expectancy gap between neighborhoods.

Methods

We conducted a spatial analysis using the green space metrics of normalized difference vegetation index(NDVI), park access, and tree canopy. Additionally, …


Examining Noncommunicable Diseases Using Satellite Imagery: A Systematic Review, Elizabeth J. Folkmann, M. Courtney Hughes, Uzma A. Khan, Mahdi Vaezi Jan 2024

Examining Noncommunicable Diseases Using Satellite Imagery: A Systematic Review, Elizabeth J. Folkmann, M. Courtney Hughes, Uzma A. Khan, Mahdi Vaezi

Faculty Articles, Papers, and Other Scholarship

Introduction

Noncommunicable diseases (NCDs) are the leading cause of morbidity and mortality worldwide, accounting for 74% of deaths annually. Satellite imagery provides previously unattainable data about factors related to NCDs that overcome limitations of traditional, non-satellite-derived environmental data, such as subjectivity and requirements of a smaller geographic area of focus. This systematic literature review determined how satellite imagery has been used to address the top NCDs in the world, including cardiovascular diseases, cancers, chronic respiratory diseases, and diabetes.

Methods

A literature search was performed using PubMed (including MEDLINE), CINAHL, Web of Science, Science Direct, Green FILE, and Engineering Village for …


Us Hospices’ Approach To Racial/ Ethnic Minority Inclusion: A Qualitative Study, M. Courtney Hughes, Erin Vernon, Monica Kowalczyk, Marlon Basco-Rodillas Jan 2024

Us Hospices’ Approach To Racial/ Ethnic Minority Inclusion: A Qualitative Study, M. Courtney Hughes, Erin Vernon, Monica Kowalczyk, Marlon Basco-Rodillas

Faculty Articles, Papers, and Other Scholarship

Objective: To examine hospices’ approaches to improving the current racial/ethnic hospice utilisation disparity.

Methods: During June and July 2020, we conducted in-depth, semistructured interviews with 22 hospice leaders from across the USA. The interviews focused on inclusive strategy approaches. We analysed the data using qualitative methods.

Results: Multiple themes emerged about racial/ ethnic minority inclusion strategies: (1) hospices tailor strategies to the local communities they serve; (2) improvement involves addressing social determinants of health that extend beyond end-of-life care; (3) costs of strategies are not a primary concern and the benefits are worth the costs; and (4) hospices want to …


Measuring Decision Aid Effectiveness For End-Of-Life Care: A Systematic Review, M. Courtney Hughes, Erin Vernon, Chinenye Egwuonwu, Oluwatoyosi Afolabi Jan 2024

Measuring Decision Aid Effectiveness For End-Of-Life Care: A Systematic Review, M. Courtney Hughes, Erin Vernon, Chinenye Egwuonwu, Oluwatoyosi Afolabi

Faculty Articles, Papers, and Other Scholarship

Objective

To systematically review research analyzing the effectiveness of decision aids for end-of-life care, including how researchers specifically measure decision aid success.

Methods

We conducted a systematic review synthesizing quantitative, qualitative, and mixed-methods study results using Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. Four databases were searched through February 18, 2023. Inclusion criteria required articles to evaluate end-of-life care decision aids. The review is registered under PROSPERO (#CRD42023408449).

Results

A total of 715 articles were initially identified, with 43 meeting the inclusion criteria. Outcome measures identified included decisional conflict, less aggressive care desired, knowledge improvements, communication improvements, tool …


Ob-Pdcds Chinese, Marianne E. Weiss, Lili Wei Jan 2024

Ob-Pdcds Chinese, Marianne E. Weiss, Lili Wei

Post-Discharge Coping Difficulty Scale (PDCDS)

The Readiness for Hospital Discharge Scale, Quality of Discharge Teaching Scale, and Post-Discharge Coping Difficulty Scale were developed by Dr. Marianne Weiss to measure nurse-sensitive discharge care processes and patient outcomes. Three versions of the scales were developed concurrently for different patient populations – Adult medical-surgical patients, Parents of hospitalized children, and Postpartum Patient mothers (see Weiss & Piacentine, 2006, Weiss et al., 2007, and Bobay et al., 2018 for description of the development and initial testing). Additional scales and information about translation rights are located at Marquette Nursing.

PERMISSION TO USE

The Readiness for Discharge Scale, Quality of Discharge …


Pdcds-Adult German, Marianne E. Weiss, Matthias Marsall Jan 2024

Pdcds-Adult German, Marianne E. Weiss, Matthias Marsall

Post-Discharge Coping Difficulty Scale (PDCDS)

The Readiness for Hospital Discharge Scale, Quality of Discharge Teaching Scale, and Post-Discharge Coping Difficulty Scale were developed by Dr. Marianne Weiss to measure nurse-sensitive discharge care processes and patient outcomes. Three versions of the scales were developed concurrently for different patient populations – Adult medical-surgical patients, Parents of hospitalized children, and Postpartum Patient mothers (see Weiss & Piacentine, 2006, Weiss et al., 2007, and Bobay et al., 2018 for description of the development and initial testing). Additional scales and information about translation rights are located at Marquette Nursing.

PERMISSION TO USE

The Readiness for Discharge Scale, Quality of Discharge …


Pdcds-Adult Korean, Marianne E. Weiss, Kim Jeoung Hee Jan 2024

Pdcds-Adult Korean, Marianne E. Weiss, Kim Jeoung Hee

Post-Discharge Coping Difficulty Scale (PDCDS)

The Readiness for Hospital Discharge Scale, Quality of Discharge Teaching Scale, and Post-Discharge Coping Difficulty Scale were developed by Dr. Marianne Weiss to measure nurse-sensitive discharge care processes and patient outcomes. Three versions of the scales were developed concurrently for different patient populations – Adult medical-surgical patients, Parents of hospitalized children, and Postpartum Patient mothers (see Weiss & Piacentine, 2006, Weiss et al., 2007, and Bobay et al., 2018 for description of the development and initial testing). Additional scales and information about translation rights are located at Marquette Nursing.

PERMISSION TO USE

The Readiness for Discharge Scale, Quality of Discharge …


Pdcds-Adult Bahasa Indonesian, Marianne E. Weiss, Azizah Khoiriyati Jan 2024

Pdcds-Adult Bahasa Indonesian, Marianne E. Weiss, Azizah Khoiriyati

Post-Discharge Coping Difficulty Scale (PDCDS)

The Readiness for Hospital Discharge Scale, Quality of Discharge Teaching Scale, and Post-Discharge Coping Difficulty Scale were developed by Dr. Marianne Weiss to measure nurse-sensitive discharge care processes and patient outcomes. Three versions of the scales were developed concurrently for different patient populations – Adult medical-surgical patients, Parents of hospitalized children, and Postpartum Patient mothers (see Weiss & Piacentine, 2006, Weiss et al., 2007, and Bobay et al., 2018 for description of the development and initial testing). Additional scales and information about translation rights are located at Marquette Nursing.

PERMISSION TO USE

The Readiness for Discharge Scale, Quality of Discharge …


Ped-Pdcds Norwegian, Marianne E. Weiss, Nina Ellefsen Lindberg Jan 2024

Ped-Pdcds Norwegian, Marianne E. Weiss, Nina Ellefsen Lindberg

Post-Discharge Coping Difficulty Scale (PDCDS)

The Readiness for Hospital Discharge Scale, Quality of Discharge Teaching Scale, and Post-Discharge Coping Difficulty Scale were developed by Dr. Marianne Weiss to measure nurse-sensitive discharge care processes and patient outcomes. Three versions of the scales were developed concurrently for different patient populations – Adult medical-surgical patients, Parents of hospitalized children, and Postpartum Patient mothers (see Weiss & Piacentine, 2006, Weiss et al., 2007, and Bobay et al., 2018 for description of the development and initial testing). Additional scales and information about translation rights are located at Marquette Nursing.

PERMISSION TO USE

The Readiness for Discharge Scale, Quality of Discharge …


Ped-Pdcds German, Marianne E. Weiss, Gaby Stoffel Jan 2024

Ped-Pdcds German, Marianne E. Weiss, Gaby Stoffel

Post-Discharge Coping Difficulty Scale (PDCDS)

The Readiness for Hospital Discharge Scale, Quality of Discharge Teaching Scale, and Post-Discharge Coping Difficulty Scale were developed by Dr. Marianne Weiss to measure nurse-sensitive discharge care processes and patient outcomes. Three versions of the scales were developed concurrently for different patient populations – Adult medical-surgical patients, Parents of hospitalized children, and Postpartum Patient mothers (see Weiss & Piacentine, 2006, Weiss et al., 2007, and Bobay et al., 2018 for description of the development and initial testing). Additional scales and information about translation rights are located at Marquette Nursing.

PERMISSION TO USE

The Readiness for Discharge Scale, Quality of Discharge …


Pdcds - Adult Portugese (Brazil), Marianne E. Weiss, Clediane Trindade Jan 2024

Pdcds - Adult Portugese (Brazil), Marianne E. Weiss, Clediane Trindade

Post-Discharge Coping Difficulty Scale (PDCDS)

The Readiness for Hospital Discharge Scale, Quality of Discharge Teaching Scale, and Post-Discharge Coping Difficulty Scale were developed by Dr. Marianne Weiss to measure nurse-sensitive discharge care processes and patient outcomes. Three versions of the scales were developed concurrently for different patient populations – Adult medical-surgical patients, Parents of hospitalized children, and Postpartum Patient mothers (see Weiss & Piacentine, 2006, Weiss et al., 2007, and Bobay et al., 2018 for description of the development and initial testing). Additional scales and information about translation rights are located at Marquette Nursing.

PERMISSION TO USE

The Readiness for Discharge Scale, Quality of Discharge …


Cultural Predictors Of Self-Esteem Among Black Women With Criminal Justice Involvement And Herpes Simplex Virus, Natalie Malone, Jardin N. Dogan-Dixon, Shemeka Thorpe, Shawndaya S. Thrasher, Paris Wheeler, Danelle Stevens-Watkins, Carrie B. Oser Jan 2024

Cultural Predictors Of Self-Esteem Among Black Women With Criminal Justice Involvement And Herpes Simplex Virus, Natalie Malone, Jardin N. Dogan-Dixon, Shemeka Thorpe, Shawndaya S. Thrasher, Paris Wheeler, Danelle Stevens-Watkins, Carrie B. Oser

Sociology Faculty Publications

Black women have disproportionately alarming HSV-2 infection rates yet receive little attention in sexual health literature. Using a strengths-based resilience framework, this study sought to determine culturally relevant protective predictors of self-esteem for Black women who are justice-involved and have HSV-2. The authors conducted secondary data analysis on data from the “Black Women in the Study of Epidemics (B-WISE) Project,” a longitudinal prospective study investigating health disparities and health services utilization among Black women with justice involvement. At baseline, N = 151 Black women with HSV-2 who were incarcerated or on probation completed survey measures assessing selfesteem, ethnic identity affirmation …


Comparison Between Acute Leukaemia Screening Tube And Lineage Specific Panels For The Diagnosis Of Acute Leukaemia At The Aga Khan University Hospital, Nairobi, Douglas Irimu Munga Jan 2024

Comparison Between Acute Leukaemia Screening Tube And Lineage Specific Panels For The Diagnosis Of Acute Leukaemia At The Aga Khan University Hospital, Nairobi, Douglas Irimu Munga

Master of Medicine in Clinical Pathology

Introduction; Acute leukaemia is a heterogeneous group of haematological malignancies. It is categorized depending on the immature cells that proliferate and replace the normal tissue in the bone marrow. The broad categories are acute myeloid leukaemia if the immature cells are myeloblasts and acute lymphoid leukaemia if lymphoblasts. Other rare categories are blastic plasmacytoid dendritic cell neoplasm (BPDCN) and acute leukaemias of ambiguous lineage which include acute undifferentiated leukaemia and mixed phenotype acute leukaemias (MPALs). The classification is important as the treatment and management differ hence a timely and accurate diagnosis is paramount. Multiparameter comparison of the immunophenotype is possible …


Somewhere Between Despair And Hope: Reflections Of A Medical Student, Meyer Herzog Jan 2024

Somewhere Between Despair And Hope: Reflections Of A Medical Student, Meyer Herzog

Quill & Scope

No abstract provided.


The Knight In Rusty Armor (Day 309), A.M. Wilson Jan 2024

The Knight In Rusty Armor (Day 309), A.M. Wilson

Quill & Scope

No abstract provided.


Radical Amazement: A Reflection On Life, Learning, And Selflessness In The Anatomy Lab, Elisheva Eisenberg Jan 2024

Radical Amazement: A Reflection On Life, Learning, And Selflessness In The Anatomy Lab, Elisheva Eisenberg

Quill & Scope

No abstract provided.


No One Told Me Why I'M Here, Emma Bloom Jan 2024

No One Told Me Why I'M Here, Emma Bloom

Quill & Scope

No abstract provided.


Serenity, Asim Ahmed Jan 2024

Serenity, Asim Ahmed

Quill & Scope

No abstract provided.


Waterfall, Ariel Stonberg Jan 2024

Waterfall, Ariel Stonberg

Quill & Scope

No abstract provided.


A Very Strange Year (Day 309), A.M. Wilson Jan 2024

A Very Strange Year (Day 309), A.M. Wilson

Quill & Scope

No abstract provided.