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2024

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Full-Text Articles in Medicine and Health Sciences

Efficacy Of Concentrated Growth Factor Membrane Versus Collagen Membrane In Treating Gingival Recession, Shazneen Kandawalla Feb 2024

Efficacy Of Concentrated Growth Factor Membrane Versus Collagen Membrane In Treating Gingival Recession, Shazneen Kandawalla

Annual Research Symposium

Creating a beautiful smile has always been a cornerstone of dental practice. Gingival recession, characterized by a downward shift of the gum line, causing uneven gum margins and an unattractive appearance.

The Vestibular Incision Subperiosteal Tunnel Access (VISTA) technique, introduced by Zadeh in 2011, offers an innovative solution for root coverage. Concentrated Growth Factor Membrane (CGF) further enhances dental repair.


Spatial Analysis Of Maxillary Central Incisors In Relation To The Nasopalatine Canal And Surrounding Alveolar Bone, Harnoor Dhillon Feb 2024

Spatial Analysis Of Maxillary Central Incisors In Relation To The Nasopalatine Canal And Surrounding Alveolar Bone, Harnoor Dhillon

Annual Research Symposium

The use of mini-implants in orthodontics has enabled greater retraction of incisors than previously achievable. This change underscores the need to understand how incisors relate to the alveolar bone and nasopalatine canal. The varying labiolingual inclination of incisors during orthodontic treatments may influence these anatomical relationships. Our study aimed to assess the spatial relationship between maxillary central incisors and the surrounding alveolar bone and nasopalatine canal.


Interplay Of Periodontal Bacterial Metabolites In The Progression Of Coronary Artery Disease: A System Biological Approach, Janakiraman V Feb 2024

Interplay Of Periodontal Bacterial Metabolites In The Progression Of Coronary Artery Disease: A System Biological Approach, Janakiraman V

Annual Research Symposium

Purpose:

The purpose of this study is to investigate the intricate relationship between periodontal disease (PD) and coronary artery disease (CAD), as evidenced by epidemiological associations. Metalloproteinase inhibitor (TIMP1) plays a pivotal role in cellular signaling, differentiation, cell death, and migration by binding to target metalloproteinases, forming complexes with other molecules (collagenases) to inactivate them. However, the expression of TIMP1 is reduced in both PD and CAD, leading to an upregulation of other metalloproteinases. This research explores the hypothesis that metabolites released from (Porphyromonas gingivalis), a prevalent bacterium in atherosclerotic patients, may inhibit TIMP1, thereby influencing CAD progression. …


Implementation Of Best Practice When Collecting Blood Cultures In The Emergency Department (Ed), Parker Grossman Feb 2024

Implementation Of Best Practice When Collecting Blood Cultures In The Emergency Department (Ed), Parker Grossman

Annual Research Symposium

The purpose of this study is to compare blood culture contamination rates in the ED before and after educational in-services on best practice.


Overlooked Dental Disease In Cbct Imaging And The Impact Of Oral Radiologist Interpretation, Jared Fausnaught Feb 2024

Overlooked Dental Disease In Cbct Imaging And The Impact Of Oral Radiologist Interpretation, Jared Fausnaught

Annual Research Symposium

This study aims to underscore the necessity for a comprehensive interpretation of Cone Beam Computed Tomography (CBCT) volume images obtained by dentists. The research demonstrates and quantifies potentially overlooked dental pathology, categorizing incidental findings into three groups: 1) requiring some form of treatment or follow-up, 2) necessitating follow-up (monitoring) only, and 3) demanding no further treatment or follow-up.


Photodynamic Therapy Effects In The Treatment Of Residual Periodontal Pockets, Kade Janes Feb 2024

Photodynamic Therapy Effects In The Treatment Of Residual Periodontal Pockets, Kade Janes

Annual Research Symposium

This systematic review examined the adjunctive effect of photodynamic therapy to treat residual pockets.


Sulforaphane Pre-Treatment Improves Cytoprotection Against Opportunistic Pathogens, Robert Darby, Nathan Clark Feb 2024

Sulforaphane Pre-Treatment Improves Cytoprotection Against Opportunistic Pathogens, Robert Darby, Nathan Clark

Annual Research Symposium

Alcohol is associated with increased mortality and morbidity globally. Pulmonary infections with opportunistic pathogens can occur in healthy humans; however, binge alcohol intoxication (≥ 0.08% BAC) is a major risk factor. We have previously shown that a single dose of alcohol comparable to binge alcohol intoxication increases infection by reducing alveolar macrophage function in vivo. The aim of this study was to 1) test the therapeutic potential of the phytonutrient sulforaphane (SFN) given as a pre-treatment, and 2) test the alcohol-induced effects on phagocytic function in murine and human macrophages in vitro.


Meet An Ipe/Cp Student Champion From Thomas Jefferson University, Joria Le, Rn, Bsn Feb 2024

Meet An Ipe/Cp Student Champion From Thomas Jefferson University, Joria Le, Rn, Bsn

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

My first involvement with JCIPE programs was with the Interprofessional Palliative Care (IPC) program. Here, I was able to meet diverse students across Jefferson from Couple and Family Therapy, Medicine, Nursing, Physical Therapy, and more. Together, we addressed case studies with our various backgrounds and learned how to build upon each other’s strengths as a precursor to our future in the field. Especially coming from a Nursing background and now shifting towards medicine, it was a great experience to apply my knowledge and intertwine it with other fields.

Since then, I have immersed myself with research relating to the Health …


Meet An Ipe/Cp Staff Champion From Thomas Jefferson University, Mollie Cherson, Mphil, Lcsw Feb 2024

Meet An Ipe/Cp Staff Champion From Thomas Jefferson University, Mollie Cherson, Mphil, Lcsw

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

In June 2021, the Integrated Behavioral Health (IBH) team was invited by JCIPE to pilot a new series of interprofessional sessions for primary care teams utilizing the ECHO (Extension for Community Healthcare Outcomes). This model has been utilized and researched worldwide to help with disseminating information across various subject matters within healthcare, with the goal of decreasing health disparities. Through use of subject matter experts, brief didactic education, and case consultations, communities of learners come together to enhance patient care and health outcomes.

The IBH team, which consists of clinicians from behavioral health, primary care, nutrition, occupational therapy, psychiatry, pharmacy, …


Translation Of Collaborative Skills From Undergraduate Interprofessional Education Curriculum To The Workplace: Results Of A Pilot Program, Erin Choice, Phd, Cscs, Shelene Thomas, Pt, Dpt, Edd, Gcs, Fnap Feb 2024

Translation Of Collaborative Skills From Undergraduate Interprofessional Education Curriculum To The Workplace: Results Of A Pilot Program, Erin Choice, Phd, Cscs, Shelene Thomas, Pt, Dpt, Edd, Gcs, Fnap

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

Background

Interprofessional education (IPE) has become an increasingly necessary component of healthcare and health science curricula (Institute of Medicine, 2015; World Health Organization, 2010). However, the longitudinal impact of IPE and students’ ability to transfer knowledge and skills from the classroom to the workplace remains unknown (Breitbach et al., 2020). Training future healthcare providers (i.e., physical therapists, occupational therapists, exercise scientists) to work in interprofessional (IP) teams should arguably begin at the undergraduate (UG) level, rather than graduate level, in order to improve effective translation of skills to the workplace (Breitbach et al., 2020; Cooper et al., 2001; Murdoch et …


Team Care Planning: Black Maternal Health Case, Kenna Hersey, Ba Feb 2024

Team Care Planning: Black Maternal Health Case, Kenna Hersey, Ba

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

In support of Thomas Jefferson University’s effort to be on the cutting edge of care, JCIPE (Jefferson Center for Interprofessional Practice & Education) supports educational programs that focus on understanding and addressing health disparities. Team Care Planning (TCP) is an educational simulation experience where teams of students from different professions collaborate with each other, and interact with standardized patients, to create a care plan. The initial case developed for TCP involves an interprofessional student team developing a discharge plan for an older adult who was hospitalized after a stroke. The interprofessional student team meets with the patient and her adult …


Spotlight On An Interprofessional Clinical Team, Andrew Chapman, Md, Emily Hajjar, Pharmd, Ms, Bcps, Bcacp, Bcgp, Lora Rhodes, Msw, Lsw, Melissa Denton, Rdn, Cso, Ldn, Lauren Hersh, Md Feb 2024

Spotlight On An Interprofessional Clinical Team, Andrew Chapman, Md, Emily Hajjar, Pharmd, Ms, Bcps, Bcacp, Bcgp, Lora Rhodes, Msw, Lsw, Melissa Denton, Rdn, Cso, Ldn, Lauren Hersh, Md

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

Take a closer look at a clinical team at Thomas Jefferson University Hospital and how they practice interprofessionally every day!

The Senior Adult Oncology (SAO) Center at Jefferson Health focuses on cancer care for adults over the age of sixty-five, taking a whole-person approach in creating a personalized treatment plan.

JCIPE interviewed an SAO team about their roles, their interprofessional dynamic, and what they have learned from each other. The team then reviewed the case of C.S.


Who Are We Inviting To The Ipe Table?, Daniel S. Ferguson, Ms Feb 2024

Who Are We Inviting To The Ipe Table?, Daniel S. Ferguson, Ms

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

“Of all the forms of inequality, injustice in health care is the most shocking and inhumane.” – Martin Luther King

Health outcomes and life expectancy in the United States of America differ substantially based on race. For example, people of color are more likely to die of cardiovascular disease or stroke; more likely to have diabetes; and have higher infant and maternal mortality rates as compared to their white counterparts (Frieden, 2013). Achieving health equity is a key focus of Healthy People 2030 (HHS, 2013), which prioritizes addressing social determinants of health, including access to timely, high-quality healthcare and effective …


Impact Of Non-Surgical Periodontal Treatment On Salivary Hif-1Α In Gingivitis & Periodontitis Patients, Srijanani S Feb 2024

Impact Of Non-Surgical Periodontal Treatment On Salivary Hif-1Α In Gingivitis & Periodontitis Patients, Srijanani S

Annual Research Symposium

To estimate and compare the level of salivary HIF-1α in periodontally & systemically healthy volunteers, generalized chronic gingivitis & periodontitis patients before and after non-surgical periodontal treatment.


Exploring The Resilience Of Two Commercial Suturing Materials Subjected To Thermocycling And Chlorhexidine Immersion: An In Vitro Study, Devadharshini Chandrasekar Feb 2024

Exploring The Resilience Of Two Commercial Suturing Materials Subjected To Thermocycling And Chlorhexidine Immersion: An In Vitro Study, Devadharshini Chandrasekar

Annual Research Symposium

To evaluate the durability of two commercially available suture materials (non absorbable Black Braided Silk and absorbable polyglactin 910) subjected to thermocycling after immersing in Chlorhexidine mouthwash.


Euglycemic Diabetic Ketoacidosis Secondary To Sodium Glucose 2 Transport Inhibitor: A Case Report, Alexis Duevel, Edward Ramirez Feb 2024

Euglycemic Diabetic Ketoacidosis Secondary To Sodium Glucose 2 Transport Inhibitor: A Case Report, Alexis Duevel, Edward Ramirez

Annual Research Symposium

The purpose of this case report is to highlight the emergence of a rare adverse drug reaction (ADR), euglycemic diabetic ketoacidosis (EDKA), associated with the use of sodium glucose transport 2 (SGLT2) inhibitors.EDKA is a rare and often misdiagnosed condition, due to the absence of hyperglycemia, but represents a life-threatening emergency. We present a unique case of a 35-year-old female patient with a past medical history of diabetes and recent diagnosis of Hashimoto’s thyroiditis. The primary objective is to provide valuable insights and education to the medical community regarding this infrequent yet significant complication. Ultimately, the goal is to enhance …


Jcipe Updates Feb 2024

Jcipe Updates

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

JCIPE Updates


From The Editors Feb 2024

From The Editors

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

As we begin a new year, we in the Jefferson Center for Interprofessional Practice and Education (JCIPE) are grateful for a fall semester and holiday season which brought connection and renewed our commitment to collaboration and inclusivity. We enjoyed seeing many of you in person again at our 8th biennial conference, when we hosted approximately 165 interprofessional colleagues from across the country and even around the world, to ponder and discuss issues of the day. We learned so much about what drives you and the field of interprofessional collaborative practice, and we appreciate this opportunity to reflect on our takeaways …


A Case Report And Review On The Anesthetic Considerations Of Anterior Mediastinal Masses, Carter A. Schulz, Joshua D. Mohs, Andrew M. Reuter Feb 2024

A Case Report And Review On The Anesthetic Considerations Of Anterior Mediastinal Masses, Carter A. Schulz, Joshua D. Mohs, Andrew M. Reuter

Aesculapius Journal (Health Sciences & Medicine)

Case summary: A 15-year-old female presented with chest pain, dyspnea, and weight loss. A chest X-ray and subsequent CT scan revealed a large anterior mediastinal mass with cervical lymphadenopathy and pericardial effusion. Two biopsies under general anesthesia were performed, with the latter confirming classic Hodgkin lymphoma, nodular sclerosis subtype.

Discussion: This case underscores the significant clinical challenges posed by anterior mediastinal masses due to their proximity to vital cardiovascular and respiratory structures. Physiologic changes during general anesthesia can exacerbate these challenges. Preoperative assessment, including imaging and symptom evaluation, is crucial to guide operative planning. It is key to individualize the …


Collaborative Healthcare: Interprofessional Practice, Education And Evaluation (Jcipe), Volume 14, Number 1, Fall 2023/Winter 2024 Feb 2024

Collaborative Healthcare: Interprofessional Practice, Education And Evaluation (Jcipe), Volume 14, Number 1, Fall 2023/Winter 2024

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

In this Issue:

  • Letter from the Editors
  • JCIPE Updates
  • Who are we inviting to the IPE table?
  • Spotlight on an Interprofessional Clinical Team
  • Team Care Planning: Black Maternal Health Case
  • Translation of Collaborative Skills from Undergraduate Interprofessional Education Curriculum to the Workplace: Results of a Pilot Program
  • Meet an IPE Staff Champion
  • Meet an IPE Student Champion


A Cost Variation Analysis Of Various Statin Preparations Available In The Egyptian Market, Radwa Ahmed Ibrahim, Marwa G. Elhennawy, Samar F. Farid Feb 2024

A Cost Variation Analysis Of Various Statin Preparations Available In The Egyptian Market, Radwa Ahmed Ibrahim, Marwa G. Elhennawy, Samar F. Farid

Bulletin of Faculty of Pharmacy Cairo University

Introduction: Dyslipidemia is one of the main risk factors for cardiovascular diseases. Statin preparations are the most effective lipid-lowering preparations that reduce the risk of mortality related to cardiovascular diseases. In the Egyptian market, various statin preparations have different strengths and prices. Aim: The current study aims to assess the percentage of cost variations among different statin medications in the Egyptian market. Methods: This is a cost variation study conducted from November to December 2022. The data were collected by using the Egyptian master on therapeutic drugs, edition 2022, and from the Egyptian Drug Database (DDB) website. The maximum and …


The Problem Of Communication Of The Sign And Symbol In The Design Of The Brand In Society: The Differences Resulting From Forgery And Imitation (Analytical Study), Sattar Al-Juboori Feb 2024

The Problem Of Communication Of The Sign And Symbol In The Design Of The Brand In Society: The Differences Resulting From Forgery And Imitation (Analytical Study), Sattar Al-Juboori

Middle East Journal of Communication Studies

The research problem focused on studying the consequences of communicating through signs and symbols in the context of the current world, given the huge amount of diverse industrial and commercial products and the challenges related to distinguishing those products. The research aims to find out the problem of perception of the sign and symbol in the designs of logos and trademarks for the consumer, the role that the sign or symbol plays in the symbolic representation of the consumer, and the desires and motivations that the brand raises for the consumer in the purchasing process. The research community is limited …


Practices For Sport-Coach Mentorship: A Historical Case Study For Coaches In Catholic Schools Today, Matt Hoven Feb 2024

Practices For Sport-Coach Mentorship: A Historical Case Study For Coaches In Catholic Schools Today, Matt Hoven

eJournal of Catholic Education in Australasia

Sport-coach mentorship is perhaps the raison d’etre for the inclusion of sports programming within Catholic schools. Coach-educators can have significant and even lifelong impact on student-athlete growth and development. But, how, exactly, should coaches act as mentors in faith-based, educational contexts? Drawing upon an extensive archival and interview research project, this paper presents a historical case study of the sport-coach mentorship of Father David Bauer, csb (1924-88), an educator and exceptional Canadian ice hockey player, coach, manager, and Hockey Hall of Fame inductee. Bauer mentored and spoke out for young sportspeople over many decades. The first part of this paper …


Associations Between Fears Related To Safety During Sleep And Self-Reported Sleep In Men And Women Living In A Low-Socioeconomic Status Setting, Arron T. L. Correia, Philippa E. Forshaw, Laura C. Roden, Gosia Lipinska, H. G. Laurie Rauch, Estelle V. Lambert, Brian T. Layden, Sirimon Reutrakul, Stephanie J. Crowley, Amy Luke, Lara R. Dugas, Dale E. Rae Feb 2024

Associations Between Fears Related To Safety During Sleep And Self-Reported Sleep In Men And Women Living In A Low-Socioeconomic Status Setting, Arron T. L. Correia, Philippa E. Forshaw, Laura C. Roden, Gosia Lipinska, H. G. Laurie Rauch, Estelle V. Lambert, Brian T. Layden, Sirimon Reutrakul, Stephanie J. Crowley, Amy Luke, Lara R. Dugas, Dale E. Rae

Parkinson School of Health Sciences and Public Health

South Africans living in low socioeconomic areas have self-reported unusually long sleep durations (approximately 9–10 h). One hypothesis is that these long durations may be a compensatory response to poor sleep quality as a result of stressful environments. This study aimed to investigate whether fear of not being safe during sleep is associated with markers of sleep quality or duration in men and women. South Africans (n = 411, 25–50 y, 57% women) of African-origin living in an urban township, characterised by high crime and poverty rates, participated in this study. Participants are part of a larger longitudinal cohort study: …


Impairment Of The Glial Phagolysosomal System Drives Prion-Like Propagation Of Huntington’S Disease, Graham Davis Feb 2024

Impairment Of The Glial Phagolysosomal System Drives Prion-Like Propagation Of Huntington’S Disease, Graham Davis

Theses and Dissertations

The ability of glia to tightly regulate neuronal health and homeostasis in the CNS is conserved across species. Yet, despite the ability to degrade protein aggregates, glia are vulnerable to the accumulation of neurotoxic amyloid aggregates during neurodegenerative disease progress, and even exacerbate their spread. A developing narrative highlights glia as a double-edged sword in neurodegenerative diseases: initially capable of dynamically responding to amyloid aggregate-ladened dying neurons but also capable of inducing chronic inflammation and creating seeding-competent amyloid oligomers. Thus, uncovering the mechanisms that allow glia to control aggregate deposition while preventing the neurotoxic effects and seed generation is vital …


Black Women Have The Highest Maternal Mortality Rate In The United States, Tori-Ann Haywood Feb 2024

Black Women Have The Highest Maternal Mortality Rate In The United States, Tori-Ann Haywood

Population Health Research Brief Series

The U.S. maternal mortality rate is consistently higher than its high-income peer countries. Since 2018 maternal mortality rates in the U.S. have steadily increased for all ethnoracial groups. This data slice uses data from the U.S. National Center for Health Statistics to describe U.S. maternity mortality rates for women ages 15-45 across different ethnoracial groups between 2018-2022. Results show that, except for non-Hispanic (NH) Asian women, ethnoracial minority women have higher maternal death rates than NH White women.


Patient–Provider Communication Quality: Socioeconomic Disparities In Smoking Outcomes, Soumya Upadhyay, Jalen Jones Feb 2024

Patient–Provider Communication Quality: Socioeconomic Disparities In Smoking Outcomes, Soumya Upadhyay, Jalen Jones

Healthcare Administration and Policy Faculty Research

Introduction:
/="/">Patient–provider communication quality is instrumental for healthy outcomes in patients. The objective of this study is to examine the relationships between patient–provider communication quality and participant characteristics, perception of e-cigarette harmfulness, and smoking outcomes.
/="/">
/="/">Methods:
/="/">A pooled cross-sectional design was used on secondary data obtained from the Health Information National Trends Survey (HINTS) 5 from Cycle 1 through Cycle 4, from 2017–2022. Our final sample contained 3511 observations. Our outcome variable was the perception of electronic cigarette smoking status. The independent variable was patient–provider communication quality (PPCQ), measured from a series of questions with responses …


Iron-Imine Cocktail In Drug Development: A Contemporary Update, Judith Anane, Esther Owusu, Gildardo Rivera-Sanchez, Debasish Bandyopadhyay Feb 2024

Iron-Imine Cocktail In Drug Development: A Contemporary Update, Judith Anane, Esther Owusu, Gildardo Rivera-Sanchez, Debasish Bandyopadhyay

School of Integrative Biological & Chemical Sciences Faculty Publications

Organometallic drug development is still in its early stage, but recent studies show that organometallics having iron as the central atom have the possibility of becoming good drug candidates because iron is an important micro-nutrient, and it is compatible with many biological systems, including the human body. Being an eco-friendly Lewis acid, iron can accept the lone pair of electrons from imino(sp2)-nitrogen, and the resultant iron-imine complexes with iron as a central atom have the possibility of interacting with several proteins and enzymes in humans. Iron-imine complexes have demonstrated significant potential with anticancer, bactericidal, fungicidal, and other medicinal activities in …


Evolution Of Physical Therapy Scholarship In The Philippines: A Scientometric Analysis Of Peer-Reviewed Publications, Rolando T. Lazaro, Catherine Joy T. Escuadra, Eric Robinson, Esmerita Rotor, Arvie C. Vitente, Edward James R. Gorgon Feb 2024

Evolution Of Physical Therapy Scholarship In The Philippines: A Scientometric Analysis Of Peer-Reviewed Publications, Rolando T. Lazaro, Catherine Joy T. Escuadra, Eric Robinson, Esmerita Rotor, Arvie C. Vitente, Edward James R. Gorgon

Rehabilitation Sciences Department Faculty Articles

Introduction. The Philippine Journal of Physical Therapy began publication in 2021. The editorial board identified as a high-priority project to undertake a detailed analysis of current publishing practice among physical therapy researchers in the Philippines.

Methods. This study systematically mined publications from Web of Science, Scopus and PubMed using the keywords “physical therapy” OR “physiotherapy” OR “physical therapist” OR “physiotherapist.” Results were further refined to only include English publicatio ns by authors from the Philippines. Publication, citation, collaboration, and text-co-occurrence network analysis were done using RStudio and VOSViewer.

Results. A total of 122 publications from 1987 to …


Investigating The "Sex Paradox" In Pulmonary Arterial Hypertension: Results From The Pulmonary Hypertension Association Registry (Phar), Jacqueline T. Desjardin, Noah Kime, Nicholas A. Kolaitis, Richard A. Kronmal, Matthew R. Lammi, Stephen C. Mathai, Corey E. Ventetuolo, Teresa De Marco Feb 2024

Investigating The "Sex Paradox" In Pulmonary Arterial Hypertension: Results From The Pulmonary Hypertension Association Registry (Phar), Jacqueline T. Desjardin, Noah Kime, Nicholas A. Kolaitis, Richard A. Kronmal, Matthew R. Lammi, Stephen C. Mathai, Corey E. Ventetuolo, Teresa De Marco

School of Medicine Faculty Publications

BACKGROUND: Female sex is a significant risk factor for pulmonary arterial hypertension (PAH), yet males with PAH have worse survival - a phenomenon referred to as the "sex paradox" in PAH. METHODS: All adult PAH patients in the Pulmonary Hypertension Association Registry (PHAR) with congruent sex and gender were included. Baseline differences in demographics, hemodynamics, functional parameters, and quality of life were assessed by sex. Kaplan-Meier survival analysis was used to evaluate survival by sex. Mediation analysis was conducted with Cox proportional hazards regression by comparing the unadjusted hazard ratios for sex before and after adjustment for covariates. The plausibility …