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2024

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Articles 18811 - 18840 of 27242

Full-Text Articles in Medicine and Health Sciences

Implementation Of A Prediabetes Decision Aid In Primary Care, Lindsay Kim Md, Beth Careyva M.D., Autumn Kieber-Emmons Md, Mph, Nicole M. Burgess Bs, Roya Hamadani Mph, Aashka Patel Mar 2024

Implementation Of A Prediabetes Decision Aid In Primary Care, Lindsay Kim Md, Beth Careyva M.D., Autumn Kieber-Emmons Md, Mph, Nicole M. Burgess Bs, Roya Hamadani Mph, Aashka Patel

USF-LVHN SELECT

No abstract provided.


Process Improvements For The Treatment Of Iron Deficiency Anemia In Pregnancy, Iris Kong Md, Natalie Chlus Md, Bradley Lash Md Mar 2024

Process Improvements For The Treatment Of Iron Deficiency Anemia In Pregnancy, Iris Kong Md, Natalie Chlus Md, Bradley Lash Md

USF-LVHN SELECT

No abstract provided.


Stroke Metrics Pre And Post Nurse Activated Alerts, Rachel A Eakins Md, Kathleen E. Kane Md, Alison Duddy Mar 2024

Stroke Metrics Pre And Post Nurse Activated Alerts, Rachel A Eakins Md, Kathleen E. Kane Md, Alison Duddy

USF-LVHN SELECT

No abstract provided.


The Effect Of Immediate Postpartum Long Acting Reversible Contraception Placement Of Short Interval Pregnancy Rates In The Lehigh Valley, Andrew Grover Md, Joanne Quiñones Md, Msce, Amanda Hess Mar 2024

The Effect Of Immediate Postpartum Long Acting Reversible Contraception Placement Of Short Interval Pregnancy Rates In The Lehigh Valley, Andrew Grover Md, Joanne Quiñones Md, Msce, Amanda Hess

USF-LVHN SELECT

No abstract provided.


Substance Use In Homeless Adolescents During The Covid-19 Pandemic, Evanie Huang Md, Marna R. Greenberg Do, Mph, Facep Mar 2024

Substance Use In Homeless Adolescents During The Covid-19 Pandemic, Evanie Huang Md, Marna R. Greenberg Do, Mph, Facep

USF-LVHN SELECT

No abstract provided.


Measuring Timeliness Of Responses To Stat Neurosurgical Trauma Consults At Lehigh Valley Hospital - Muhlenberg, Amanda Brisco Md, Joseph J. Stirparo Md, Bree A. Harrison Bsn, Rn, Tcrn, Jaclyn Sharkazy Pa-C, Mspas, Emily Bear Bsn, Rn, Ccrn, Tcrn Mar 2024

Measuring Timeliness Of Responses To Stat Neurosurgical Trauma Consults At Lehigh Valley Hospital - Muhlenberg, Amanda Brisco Md, Joseph J. Stirparo Md, Bree A. Harrison Bsn, Rn, Tcrn, Jaclyn Sharkazy Pa-C, Mspas, Emily Bear Bsn, Rn, Ccrn, Tcrn

USF-LVHN SELECT

No abstract provided.


Lvhn Pediatric Community Acquired Pneumonia Pathway, Berwin Yuan Md, Janice Joseph Do, Kris Rooney Md Mar 2024

Lvhn Pediatric Community Acquired Pneumonia Pathway, Berwin Yuan Md, Janice Joseph Do, Kris Rooney Md

USF-LVHN SELECT

No abstract provided.


The Attitude Of Medical Students Toward Lgbtq Older Adults Before And After Intervention, Suzanna S Tom Md, Lynn M. Wilson Do Mar 2024

The Attitude Of Medical Students Toward Lgbtq Older Adults Before And After Intervention, Suzanna S Tom Md, Lynn M. Wilson Do

USF-LVHN SELECT

No abstract provided.


Pre-Stimulus Bioelectrical Activity In Light-Adapted Erg Under Blue Vs. White Background, Katherine Tsay Md, Sara Safari Md, Abdullah Abou-Samra, Jan Kremers, Radouil Tzekov Mar 2024

Pre-Stimulus Bioelectrical Activity In Light-Adapted Erg Under Blue Vs. White Background, Katherine Tsay Md, Sara Safari Md, Abdullah Abou-Samra, Jan Kremers, Radouil Tzekov

USF-LVHN SELECT

No abstract provided.


Sex Differences In Brain Mri Of Patients With Migraines, Y Su, S Singh, Victoria Qizhi Tay Md, Vitaliy Koss Md, Megan Leary Md, Hope Kincaid Mph, Cph, Hussam A. Yacoub Md, John Castaldo Md Mar 2024

Sex Differences In Brain Mri Of Patients With Migraines, Y Su, S Singh, Victoria Qizhi Tay Md, Vitaliy Koss Md, Megan Leary Md, Hope Kincaid Mph, Cph, Hussam A. Yacoub Md, John Castaldo Md

USF-LVHN SELECT

No abstract provided.


Transiam: Aggregating Multi-Modal Visual Features With Locality For Medical Image Segmentation, Xuejian Li, Shiqiang Ma, Junhai Xu, Jijun Tang, Shengfeng He, Fei Guo Mar 2024

Transiam: Aggregating Multi-Modal Visual Features With Locality For Medical Image Segmentation, Xuejian Li, Shiqiang Ma, Junhai Xu, Jijun Tang, Shengfeng He, Fei Guo

Research Collection School Of Computing and Information Systems

Automatic segmentation of medical images plays an important role in the diagnosis of diseases. On single-modal data, convolutional neural networks have demonstrated satisfactory performance. However, multi-modal data encompasses a greater amount of information rather than single-modal data. Multi-modal data can be effectively used to improve the segmentation accuracy of regions of interest by analyzing both spatial and temporal information. In this study, we propose a dual-path segmentation model for multi-modal medical images, named TranSiam. Taking into account that there is a significant diversity between the different modalities, TranSiam employs two parallel CNNs to extract the features which are specific to …


Dupilumab-Induced Pityriasis Rosea In A 28-Year-Old Male With Atopic Dermatitis., Faraz Yousefian, Margaret Hurley, Liaqat Ali, Marcus Goodman, Katherine Rupley Mar 2024

Dupilumab-Induced Pityriasis Rosea In A 28-Year-Old Male With Atopic Dermatitis., Faraz Yousefian, Margaret Hurley, Liaqat Ali, Marcus Goodman, Katherine Rupley

PCOM Scholarly Works

No abstract provided.


A Baker's Dozen Of Top Antimicrobial Stewardship Intervention Publications In 2022., Reagan K Barfield, Matthew L Brown, Benjamin Albrecht, Katie E Barber, Jeannette Bouchard, Amy L Carr, Elias B Chahine, David Cluck, Elizabeth W Covington, Connor R Deri, Spencer H Durham, Carmen Faulkner-Fennell, Lauren K Freeman, Timothy P Gauthier, Geneen M Gibson, Sarah B Green, Athena L V Hobbs, Bruce M Jones, Caroline C Jozefczyk, Ashley H Marx, Edo-Abasi U. Mcgee, Lacie J Mckamey, Rachel Musgrove, Emily Perez, Douglas Slain, Kayla R Stover, Michelle S Turner, Cyle White, P Brandon Bookstaver, Christopher M Bland Mar 2024

A Baker's Dozen Of Top Antimicrobial Stewardship Intervention Publications In 2022., Reagan K Barfield, Matthew L Brown, Benjamin Albrecht, Katie E Barber, Jeannette Bouchard, Amy L Carr, Elias B Chahine, David Cluck, Elizabeth W Covington, Connor R Deri, Spencer H Durham, Carmen Faulkner-Fennell, Lauren K Freeman, Timothy P Gauthier, Geneen M Gibson, Sarah B Green, Athena L V Hobbs, Bruce M Jones, Caroline C Jozefczyk, Ashley H Marx, Edo-Abasi U. Mcgee, Lacie J Mckamey, Rachel Musgrove, Emily Perez, Douglas Slain, Kayla R Stover, Michelle S Turner, Cyle White, P Brandon Bookstaver, Christopher M Bland

PCOM Scholarly Works

Keeping abreast of the antimicrobial stewardship-related articles published each year is challenging. The Southeastern Research Group Endeavor identified antimicrobial stewardship-related, peer-reviewed literature that detailed an actionable intervention during 2022. The top 13 publications were selected using a modified Delphi technique. These manuscripts were reviewed to highlight actionable interventions used by antimicrobial stewardship programs to capture potentially effective strategies for local implementation.


Advances In Pediatric Acute Kidney Injury Pathobiology: A Report From The 26th Acute Disease Quality Initiative (Adqi) Conference, Michelle C Starr, Erin Barreto, Jennifer Charlton, Molly Vega, Patrick D Brophy, O N Ray Bignall, Scott M Sutherland, Shina Menon, Prasad Devarajan, Ayse Akcan Arikan, Rajit Basu, Stuart Goldstein, Danielle E Soranno Mar 2024

Advances In Pediatric Acute Kidney Injury Pathobiology: A Report From The 26th Acute Disease Quality Initiative (Adqi) Conference, Michelle C Starr, Erin Barreto, Jennifer Charlton, Molly Vega, Patrick D Brophy, O N Ray Bignall, Scott M Sutherland, Shina Menon, Prasad Devarajan, Ayse Akcan Arikan, Rajit Basu, Stuart Goldstein, Danielle E Soranno

Faculty, Staff and Students Publications

Background: In the past decade, there have been substantial advances in our understanding of the pathobiology of pediatric acute kidney injury (AKI). In particular, animal models and studies focused on the relationship between kidney development, nephron number, and kidney health have identified a number of heterogeneous pathophysiologies underlying AKI. Despite this progress, gaps remain in our understanding of the pathobiology of pediatric AKI.

Methods: During the 26th Acute Disease Quality Initiative (ADQI) Consensus conference, a multidisciplinary group of experts discussed the evidence and used a modified Delphi process to achieve consensus on recommendations for opportunities to advance translational research in …


Validation Of Distinct Bladder Pain Phenotypes Utilizing The Mapp Research Network Cohort, Oluwarotimi Sewedo Nettey, Cindy Gu, Nicholas James Jackson, A Lenore Ackerman Mar 2024

Validation Of Distinct Bladder Pain Phenotypes Utilizing The Mapp Research Network Cohort, Oluwarotimi Sewedo Nettey, Cindy Gu, Nicholas James Jackson, A Lenore Ackerman

Faculty, Staff and Students Publications

Introduction and hypothesis: As interstitial cystitis/bladder pain syndrome (IC/BPS) likely represents multiple pathophysiologies, we sought to validate three clinical phenotypes of IC/BPS patients in a large, multi-center cohort using unsupervised machine learning (ML) analysis.

Methods: Using the female Genitourinary Pain Index and O'Leary-Sant Indices, k-means unsupervised clustering was utilized to define symptomatic phenotypes in 130 premenopausal IC/BPS participants recruited through the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) research network. Patient-reported symptoms were directly compared between MAPP ML-derived phenotypic clusters to previously defined phenotypes from a single center (SC) cohort.

Results: Unsupervised ML categorized IC/BPS participants into …


Long-Term Follow-Up For Recipients Of Genetically Modified Cells: A Team Effort, Helen E Heslop Mar 2024

Long-Term Follow-Up For Recipients Of Genetically Modified Cells: A Team Effort, Helen E Heslop

Faculty, Staff and Students Publications

No abstract provided.


Diabetes Study Of Children Of Diverse Ethnicity And Race: Study Design, Maria J Redondo, Kylie K Harrall, Deborah H Glueck, Mustafa Tosur, Serife Uysal, Andrew Muir, Elizabeth G Atkinson, Melanie R Shapiro, Liping Yu, William E Winter, Michael Weedon, Todd M Brusko, Richard Oram, Kendra Vehik, William Hagopian, Mark A Atkinson, Dana Dabelea, Discover Study Group Mar 2024

Diabetes Study Of Children Of Diverse Ethnicity And Race: Study Design, Maria J Redondo, Kylie K Harrall, Deborah H Glueck, Mustafa Tosur, Serife Uysal, Andrew Muir, Elizabeth G Atkinson, Melanie R Shapiro, Liping Yu, William E Winter, Michael Weedon, Todd M Brusko, Richard Oram, Kendra Vehik, William Hagopian, Mark A Atkinson, Dana Dabelea, Discover Study Group

Faculty, Staff and Students Publications

AIMS: Determining diabetes type in children has become increasingly difficult due to an overlap in typical characteristics between type 1 diabetes (T1D) and type 2 diabetes (T2D). The Diabetes Study in Children of Diverse Ethnicity and Race (DISCOVER) programme is a National Institutes of Health (NIH)-supported multicenter, prospective, observational study that enrols children and adolescents with non-secondary diabetes. The primary aim of the study was to develop improved models to differentiate between T1D and T2D in diverse youth.

MATERIALS AND METHODS: The proposed models will evaluate the utility of three existing T1D genetic risk scores in combination with data on …


Can Steam Be Usable As A "Plus" For Ventilation Shutdown?, A. V. Mendoza, S. Weimer, Z. Williams Mar 2024

Can Steam Be Usable As A "Plus" For Ventilation Shutdown?, A. V. Mendoza, S. Weimer, Z. Williams

Poultry Science Faculty Publications and Presentations

The American Veterinary Medical Association (AVMA), preferred depopulation methods (i.e., foam, containerized gassing, and mechanical methods) can be challenging when depopulating cage and aviary commercial laying hen houses for multiple reasons. When preferred methods are not feasible or resources are unavailable, ventilation shutdown plus (VSD+) heat and/or carbon dioxide (CO2) is approved for emergency situations. Both recognized “pluses” work but can have issues as VSD+ heat typically causes a decrease in environmental humidity and can affect PVC structures, while CO2 can be a human safety concern and has procurement problem during emergencies. …


Fatty Acids And Their Proteins In Adipose Tissue Inflammation, Rahul Mallick, Sanjay Basak, Ranjit Kumar Das, Antara Banerjee, Sujay Paul, Surajit Pathak, Asim K. Duttaroy Mar 2024

Fatty Acids And Their Proteins In Adipose Tissue Inflammation, Rahul Mallick, Sanjay Basak, Ranjit Kumar Das, Antara Banerjee, Sujay Paul, Surajit Pathak, Asim K. Duttaroy

Health & Biomedical Sciences Faculty Publications

Chronic low-grade adipose tissue inflammation is associated with metabolic disorders. Inflammation results from the intertwined cross-talks of pro-inflammatory and anti-inflammatory pathways in the immune response of adipose tissue. In addition, adipose FABP4 levels and lipid droplet proteins are involved in systemic and tissue inflammation. Dysregulated adipocytes help infiltrate immune cells derived from bone marrow responsible for producing cytokines and chemokines. When adipose tissue expands in excess, adipocyte exhibits increased secretion of adipokines and is implicated in metabolic disturbances due to the release of free fatty acids. This review presents an emerging concept in adipose tissue fat metabolism, fatty acid handling …


Effect Of A Microencapsulated Phyto/Phycogenic Blend Supplementation On Growth Performance, Processing Parameters, Meat Quality, And Sensory Profile In Male Broilers, Garrett J. Mullenix, Elizabeth S. Greene, Alison Ramser, Clay Maynard, Sami Dridi Mar 2024

Effect Of A Microencapsulated Phyto/Phycogenic Blend Supplementation On Growth Performance, Processing Parameters, Meat Quality, And Sensory Profile In Male Broilers, Garrett J. Mullenix, Elizabeth S. Greene, Alison Ramser, Clay Maynard, Sami Dridi

Poultry Science Faculty Publications and Presentations

Powered by consumer taste, value, and preferences, natural products including phytogenics and algae are increasingly and separately used in the food systems where they have been reported to improve growth performance in poultry and livestock. The present study aimed to determine the effects of a new feed additive, microencapsulated NUQO© NEX, which contains a combination of phytogenic and phycogenic, on broiler growth performance, blood chemistry, bone health, meat quality and sensory profile. Male Cobb500 chicks (n = 1,197) were fed a 3-phase feeding intervals; 1–14d starter, 15–28d grower, and 29–40d finisher. The dietary treatments included a corn-soy basal Control …


Possible Role Of Correlation Coefficients And Network Analysis Of Multiple Intracellular Proteins In Blood Cells Of Patients With Bipolar Disorder In Studying The Mechanism Of Lithium Responsiveness: A Proof-Concept Study, Keming Gao, Marzieh Ayati, Nicholas M. Kaye, Mehmet Koyutürk, Joseph R. Calabrese, Eric Christian, Hillard M. Lazarus, David Kaplan Mar 2024

Possible Role Of Correlation Coefficients And Network Analysis Of Multiple Intracellular Proteins In Blood Cells Of Patients With Bipolar Disorder In Studying The Mechanism Of Lithium Responsiveness: A Proof-Concept Study, Keming Gao, Marzieh Ayati, Nicholas M. Kaye, Mehmet Koyutürk, Joseph R. Calabrese, Eric Christian, Hillard M. Lazarus, David Kaplan

Computer Science Faculty Publications

Background: The mechanism of lithium treatment responsiveness in bipolar disorder (BD) remains unclear. The aim of this study was to explore the utility of correlation coefficients and protein-to-protein interaction (PPI) network analyses of intracellular proteins in monocytes and CD4+ lymphocytes of patients with BD in studying the potential mechanism of lithium treatment responsiveness. Methods: Patients with bipolar I or II disorder who were diagnosed with the MINI for DSM-5 and at any phase of the illness with at least mild symptom severity and received lithium (serum level ≥ 0.6 mEq/L) for 16 weeks were divided into two groups, responders (≥50% …


A Systematic Review Of Measures Of Healthcare Workers’ Vaccine Confidence, Kofoworola Akinsola, Ayobami Bakare, Elisa Gobbo, Carina King, Claudia Hanson, Adegoke Falade, Sibylle Herzig Van Wees Mar 2024

A Systematic Review Of Measures Of Healthcare Workers’ Vaccine Confidence, Kofoworola Akinsola, Ayobami Bakare, Elisa Gobbo, Carina King, Claudia Hanson, Adegoke Falade, Sibylle Herzig Van Wees

Centre of Excellence in Women and Child Health

Healthcare workers (HCW) perceptions toward vaccines influence patient and community vaccine decision making. In an era of rising vaccine hesitancy, understanding HCW vaccine confidence is critical. This systematic review aims to review instruments that have been validated to measure HCW vaccine confidence. We conducted a search in five databases in June 2023. Data was descriptively synthesized. Twelve articles describing 10 different tools were included. Most tools included dimensions or items on vaccine knowledge (n = 9), safety (n = 8), vaccine usefulness (n = 8), recommendation behavior (n = 8), and self-vaccination practice (n = 7). All, except one study, …


Navigating Through Chaos, Hoong Chuin Lau Mar 2024

Navigating Through Chaos, Hoong Chuin Lau

Asian Management Insights

How AI and optimisation models can strengthen supply chain resilience.


Ensuring Intervention Fidelity Of An Attention Control Arm In A Multisite Randomized Controlled Trial, Amy R. Newman, Karen M. Moody, Kerri Becktell, Erin Connelly, Cynthia Holladay, Katie Parisio, Jonathan L. Powell, Verna L. Hendricks-Ferguson Mar 2024

Ensuring Intervention Fidelity Of An Attention Control Arm In A Multisite Randomized Controlled Trial, Amy R. Newman, Karen M. Moody, Kerri Becktell, Erin Connelly, Cynthia Holladay, Katie Parisio, Jonathan L. Powell, Verna L. Hendricks-Ferguson

College of Nursing Faculty Research and Publications

Background

Intervention fidelity is a critical element of randomized controlled trials, yet reporting of intervention fidelity among attention control arms is limited. Lack of fidelity to attention control procedures can affect study outcomes by either overestimating or underestimating the efficacy of the intervention under examination.

Objectives

This brief report describes the approach researchers took to promote fidelity to the attention control arm of a pediatric palliative care randomized controlled trial funded by the National Institutes of Health.

Methods

The Informational Meetings for Planning and Coordinating Treatment trial aims to determine the efficacy of a communication intervention that uses care team …


Invited Commentary On Andersen S, Et Al Developmental Windows Of Environmental Vulnerability For Inflammatory Bowel Disease, David A Simon, Richard Kellermayer Mar 2024

Invited Commentary On Andersen S, Et Al Developmental Windows Of Environmental Vulnerability For Inflammatory Bowel Disease, David A Simon, Richard Kellermayer

Faculty, Staff and Students Publications

No abstract provided.


A Survey Assessment Of Neurosurgeons' Interest In Osteopathic Medicine And Its Integration Into Their Practice., Devin W Kolmetzky, Dillon B Gooder, Evan S Polly, Sarah N Glisan, Zein Al-Atrache, Clint A Badger, Steven S Yocom, Alan R Turtz, Donald Allison Mar 2024

A Survey Assessment Of Neurosurgeons' Interest In Osteopathic Medicine And Its Integration Into Their Practice., Devin W Kolmetzky, Dillon B Gooder, Evan S Polly, Sarah N Glisan, Zein Al-Atrache, Clint A Badger, Steven S Yocom, Alan R Turtz, Donald Allison

PCOM Scholarly Works

INTRODUCTION: Osteopathic manipulative medicine (OMM) encompasses techniques guided by the tenets of osteopathy aimed at facilitating the body's natural self-healing capabilities as a treatment option for injury or illness. This approach recognizes the interrelationship of structure and function in promoting overall health. The clinical applications of OMM have been highly researched throughout different subspecialties of medicine; however, there is a notable lack of osteopathic-based research targeted toward neurosurgical patient populations.

METHODS: This cross-sectional descriptive study was conducted via a survey generated using SurveyMonkey (SurveyMonkey, San Mateo, CA, USA; accessed at www.surveymonkey.com). Subjects for this survey were gathered using a convenience …


People With Degenerative Cervical Myelopathy Have Impaired Reactive Balance During Walking, Timothy F. Boerger, Learon Mcginn, Megan Bellman, Marjorie C. Wang, Brian D. Schmit, Allison S. Hyngstrom Mar 2024

People With Degenerative Cervical Myelopathy Have Impaired Reactive Balance During Walking, Timothy F. Boerger, Learon Mcginn, Megan Bellman, Marjorie C. Wang, Brian D. Schmit, Allison S. Hyngstrom

Physical Therapy Faculty Research and Publications

Background

People with degenerative cervical myelopathy are known to have impaired standing balance and walking abilities, but less is known about balance responses during walking.

Research question

The aim of this project was to assess reactive balance impairments during walking in people with degenerative cervical myelopothy (PwDCM). We hypothesized that center of mass motion following perturbations would be larger in PwDCM and gluteus medius electromyographic amplitude responses would be decreased in PwDCM.

Methods

Reactive balance responses were quantified during unanticipated lateral pulls to the waist while treadmill walking. Walking biomechanics data were collected from 10 PwDCM (F=6) and 10 non-myelopathic …


Autologous Cell Immunotherapy (Igv-001) With Igf-1r Antisense Oligonucleotide In Newly Diagnosed Glioblastoma Patients, Ian Y. Lee, Simon Hanft, Michael Schulder, Kevin D. Judy, Eric T. Wong, J. Bradley Elder, Linton T. Evans, Mario Zuccarello, Julian Wu, Sonikpreet Aulakh, Vijay Agarwal, Rohan Ramakrishna, Brian J. Gill, Alfredo Quiñones-Hinojosa, Cameron Brennan, Brad E. Zacharia, Carlos Eduardo Silva Correia, Madhavi Diwanji, Gregory K. Pennock, Charles Scott, Raul Perez-Olle, David W. Andrews, John A. Boockvar Mar 2024

Autologous Cell Immunotherapy (Igv-001) With Igf-1r Antisense Oligonucleotide In Newly Diagnosed Glioblastoma Patients, Ian Y. Lee, Simon Hanft, Michael Schulder, Kevin D. Judy, Eric T. Wong, J. Bradley Elder, Linton T. Evans, Mario Zuccarello, Julian Wu, Sonikpreet Aulakh, Vijay Agarwal, Rohan Ramakrishna, Brian J. Gill, Alfredo Quiñones-Hinojosa, Cameron Brennan, Brad E. Zacharia, Carlos Eduardo Silva Correia, Madhavi Diwanji, Gregory K. Pennock, Charles Scott, Raul Perez-Olle, David W. Andrews, John A. Boockvar

Department of Neurosurgery Faculty Papers

Standard-of-care first-line therapy for patients with newly diagnosed glioblastoma (ndGBM) is maximal safe surgical resection, then concurrent radiotherapy and temozolomide, followed by maintenance temozolomide. IGV-001, the first product of the Goldspire™ platform, is a first-in-class autologous immunotherapeutic product that combines personalized whole tumor-derived cells with an antisense oligonucleotide (IMV-001) in implantable biodiffusion chambers, with the intent to induce a tumor-specific immune response in patients with ndGBM. Here, we describe the design and rationale of a randomized, double-blind, phase IIb trial evaluating IGV-001 compared with placebo, both followed by standard-of-care treatment in patients with ndGBM. The primary end point is progression-free …


Demographics And Paindetect As Predictors Of 24-Month Outcomes For 10 Khz Scs In Nonsurgical Refractory Back Pain, Leonardo Kapural, Chengyuan Wu, Aaron Calodney, Julie Pilitsis, Markus Bendel, Erika Petersen, Dawood Sayed, Colleen Kelly, Rose Province-Azalde, Naresh P. Patel Mar 2024

Demographics And Paindetect As Predictors Of 24-Month Outcomes For 10 Khz Scs In Nonsurgical Refractory Back Pain, Leonardo Kapural, Chengyuan Wu, Aaron Calodney, Julie Pilitsis, Markus Bendel, Erika Petersen, Dawood Sayed, Colleen Kelly, Rose Province-Azalde, Naresh P. Patel

Department of Neurosurgery Faculty Papers

BACKGROUND: Nonsurgical refractory back pain (NSRBP) is broadly defined as chronic refractory back pain in patients who have not had previous spine surgery and, because they are deemed inappropriate candidates for surgery, are reliant on conventional medical management (CMM), which often provides poor long-term outcomes. High-frequency spinal cord stimulation (10kHz SCS) has demonstrated high rates of pain relief and improvements in functioning in patients with NSRBP. However, despite the use of temporary trial stimulation to select patients who will respond to therapy, some patients fail to achieve long-term therapy response with permanent implants. Prediction analysis founded on patients' baseline characteristics …


Validation Of A Whole Blood Machine Learning Strategy For Distinguishing Between Bacterial And Viral Infection In A Pediatric Hospital Setting, Ridwan B Ibrahim, Herda Ona, Anil K Chokkalla, Estella Tam, Sridevi Devaraj Mar 2024

Validation Of A Whole Blood Machine Learning Strategy For Distinguishing Between Bacterial And Viral Infection In A Pediatric Hospital Setting, Ridwan B Ibrahim, Herda Ona, Anil K Chokkalla, Estella Tam, Sridevi Devaraj

Faculty, Staff and Students Publications

Similar symptoms between viral and bacterial diseases often make diagnosis difficult. This study assessed the clinical performance of the newly cleared whole-blood Bacterial versus Viral Score assay in our pediatric cohort to the previously validated serum assay and emergency department physician diagnosis. This assay shows excellent agreement (R = 0.997) with the serum assay and has great diagnostic accuracy when compared to physician diagnosis.