Medicine and Health Sciences Commons^™

Examining The Relationship Between Adverse Childhood Experiences, Coping Behaviors, And Metabolic Syndrome In Mexican-American Men, Paulina Torres

Open Access Theses & Dissertations

Background: The prevalence of metabolic syndrome (MetS) has been increasing in the US over recent years. Individuals who have experienced adverse childhood experiences (ACEs) and developed maladaptive coping strategies are at increased risk of developing MetS. Hispanic men might have an increased risk of developing MetS due to higher exposure to ACEs and increased use of maladaptive coping strategies.Purpose: To examine the relationship between ACEs, coping, and MetS among Mexican-American men. Methods: A secondary analysis of cross-sectional study of 100 adult men from El Paso, Texas in 2018-19. ACEs were examined using the 10-item ACE questionnaire. Coping was assessed through …

Implementing The Methodology To Generate Diagnostic And Therapeutic Antibodies, Andrea Mariana Carlin

Open Access Theses & Dissertations

This research aimed to establish the methodology for developing monoclonal antibodies at The University of Texas at El Paso. Monoclonal antibodies are indispensable across multiple fields, including diagnostics, therapeutics, and biotechnology, yet there is a shortage of commercially available antibodies targeting specific proteins or possessing specialized characteristics. To address this gap, three models were selected: a peptide derived from the intracellular protein Schlafen 8 and two cell surface protein receptors: mouse vascular endothelial growth factor receptor 2 (VEGFR2) and human melanocortin receptor 4 (MC4R). These proteins present unique challenges in antibody generation, including issues of accessibility, expression, and specificity.

Throughout …

Psychological Distress Among Family Caregivers Of Persons With Alzheimer’S Disease And Related Dementias In Uganda, Martha Sajatovic

Faculty Scholarship

Background: Alzheimer's disease and related dementias (ADRD) present growing global health challenges, especially in aging populations, such as Uganda. In Uganda, familial caregiving, predominantly undertaken by female relatives, is the primary form of support provided to patients with ADRD. Cultural stigma around dementia and limited access to support services amplify caregivers' challenges. This study examined psychological distress, depression, and quality of life (QoL) among family caregivers of patients with ADRD in Wakiso District, Uganda. Methods: This cross-sectional study involved 90 caregivers from three sub-counties in Wakiso, selected through purposive sampling to capture diverse experiences. Participants included caregivers aged 18 years …

Metabolic Shifts In Ratio Of Ucocn To Cocn Toward Bone Resorption Contribute To Age-Dependent Bone Loss In Male Mice, Matthew Bernhard, Obinna Okorie, Wei-Ju Louis Tseng, Mengcun Chen, Julia Danon, Mingshu Cui, Elisabeth Lashbrooks, Yanmei Yang, Bin Wang

Center for Translational Medicine Faculty Papers

The study of the senile osteoporosis in men still lags significantly behind that in women. The changes of protein molecule levels and their relationships with bone loss remain poorly understood. In the present study, we used C57BL/6J male mice at ages from 3 to 24 mo to delineate the mechanisms of aging effects on bone loss. We used the microcomputed tomography, mechanical testing, histomorphometry assays, and detection of serum levels of undercarboxylated osteocalcin (ucOcn) and carboxylated osteocalcin (cOcn) to assess bone mass changes and their relationships with the ratios of ucOcn-to-cOcn in mice from different age groups. The results showed …

Obesity: Influencing Behavioral Consumption Through Meal Kit Distribution, Alejandro Hernandez

Capstone Projects and Master's Theses

Founded in 2002, Everyone’s Harvest is a grassroots nonprofit dedicated to providing access to healthy, affordable fruits and vegetables through certified farmers markets and community food programs. Its key initiatives—Fresh Rx, Market Match, Edible Education and Farms Together —focus on alleviating nutrition insecurity and combating diet-related health conditions by providing vulnerable populations the resources to purchase, or receive, fresh produce and gain nutritional knowledge. This study explores a new intervention: the distribution of farmers' market meal kits as a complementary strategy to the current Edible Education program. These meal kits, which feature seasonally available produce and pre-measured ingredients, aim to …

Bridging The Gap: Fostering Open Dialogue On Resource Access And Service Needs, Cameron Castillo

Capstone Projects and Master's Theses

This project investigates whether there are additional resources desired by clients or are needed to better support said clients in their recovery at the Interim, Inc. organization. This agency is a nonprofit organization whose sole purpose is to build community connections through providing services to individuals facing mental health and substance use challenges. While there is a wide range of programs available, there may still be clients with unmet needs. The purpose of this project was to identify any service gaps by conducting separate surveys of clients and staff members. Through the use of open-ended questions, the expectation of receiving …

Comprehensive Community Medicine, Alexander Walther

Capstone Projects and Master's Theses

Comprehensive Community Medicine (CCM) is a theoretical framework designed to address the complex needs of individuals with dual diagnoses of mental illness and substance use disorders (SUDs). Dual diagnosis is highly prevalent, particularly among populations experiencing homelessness, and is associated with poorer health outcomes and increased healthcare service utilization. Structural inequities, including a fractured healthcare system, exacerbate the challenges faced by this vulnerable group. Research indicates that effective care for dually diagnosed individuals requires a layered approach addressing clinical, systemic, legal, and housing barriers.

The development of CCM has been informed by interviews with local stakeholders, including County EMS board …

Parenting With Grace, Eva Nelson Cole

Capstone Projects and Master's Theses

Parents are often caught off guard by the upheaval of adding children to their lives. Feelings of guilt, shame, isolation, and depression can arise when parents are faced with the demands and stressors that come along with having children. Studies have shown that children who have distressed parents endure lasting negative outcomes that can extend into the primary school years (Mihelic et al., 2018). Educating parents and giving them some awareness about what to expect can make a real difference. To have these conversations, I created a two-part parenting workshop for new parents at Parents’ Place in Pacific Grove, CA. …

Chatgpt Vs Expert-Guided Care Pathways For Postesophagectomy Symptom Management, Mohamad K Abou Chaar, Giovanna Grigsby-Rocca, Ming Huang, Shanda H Blackmon

Faculty, Staff and Student Publications

BACKGROUND: The objective of this study was to compare generative artificial intelligence-initiated care pathways, using ChatGPT, with expert-guided consensus-initiated care pathways from AskMayoExpert (AME) for symptom management of esophageal cancer patients after esophagectomy.

METHODS: A formal protocol for development of 9 AME care pathways was followed for specific patient-identified domains after esophagectomy for esophageal cancer. Domain scores were measured and assessed through the Upper Digestive Disease tool. These care pathways were developed by experts validated by a consensus-driven methodology. ChatGPT was used to answer specific questions similar to the AME care pathway on April 9, 2023, and March 28, 2024. …

Addressing Ethical Issues In Healthcare Artificial Intelligence Using A Lifecycle-Informed Process, Benjamin X Collins, Jean-Christophe Bélisle-Pipon, Barbara J Evans, Kadija Ferryman, Xiaoqian Jiang, Camille Nebeker, Laurie Novak, Kirk Roberts, Martin Were, Zhijun Yin, Vardit Ravitsky, Joseph Coco, Rachele Hendricks-Sturrup, Ishan Williams, Ellen W Clayton, Bradley A Malin, Bridge2ai Ethics And Trustworthy Ai Working Group

Faculty, Staff and Student Publications

OBJECTIVES: Artificial intelligence (AI) proceeds through an iterative and evaluative process of development, use, and refinement which may be characterized as a lifecycle. Within this context, stakeholders can vary in their interests and perceptions of the ethical issues associated with this rapidly evolving technology in ways that can fail to identify and avert adverse outcomes. Identifying issues throughout the AI lifecycle in a systematic manner can facilitate better-informed ethical deliberation.

MATERIALS AND METHODS: We analyzed existing lifecycles from within the current literature for ethical issues of AI in healthcare to identify themes, which we relied upon to create a lifecycle …

Targeting The Glutamine-Arginine-Proline Metabolism Axis In Cancer, Di Wang, Jiang-Jie Duan, Yu-Feng Guo, Jun-Jie Chen, Tian-Qing Chen, Jun Wang, Shi-Cang Yu

Faculty, Staff and Student Publications

Metabolic abnormalities are an important feature of tumours. The glutamine-arginine-proline axis is an important node of cancer metabolism and plays a major role in amino acid metabolism. This axis also acts as a scaffold for the synthesis of other nonessential amino acids and essential metabolites. In this paper, we briefly review (1) the glutamine addiction exhibited by tumour cells with accelerated glutamine transport and metabolism; (2) the methods regulating extracellular glutamine entry, intracellular glutamine synthesis and the fate of intracellular glutamine; (3) the glutamine, proline and arginine metabolic pathways and their interaction; and (4) the research progress in tumour therapy …

Genetic Ablation Of The Isoform Γ Of Pi3k Decreases Antidepressant Efficacy Of Ketamine In Male Mice, Gabriela N Vaz, Flávia C Turcato, Isabel A V Lima, Franciele F Scarante, Melissa R Araújo, Tamires A V Brigante, Livia C M Rodrigues, Francisco S Guimarães, Jaime E C Hallak, Jose A Crippa, Antonio L Teixeira, Antonio C P De Oliveira, Alline Cristina Campos

Faculty, Staff and Student Publications

About one-third of major depressive disorder (MDD) patients demonstrate unresponsiveness to classic antidepressants, and even the clinical efficacy of fast-acting drugs such as ketamine varies significantly among patients with treatment-resistant depression. Nevertheless, the lack of suitable animal models that mimic a possible ketamine-resistant phenotype challenges the understanding of resistance to drug treatment. In this study, we showed that PI3Kγ knock-out (KO) mice do not respond to classical doses of ketamine and classical antidepressants. PI3Kγ KO mice were unresponsive to both the rapid and sustained antidepressant-like effects of a single dose of ketamine in the forced swimming test. Additionally, they were …

A031: Design And Practice Of Ai-Powered Precision Teaching Model For Public Physical Education Courses In Universities, Dongxiao Liu, Xuankun Sun, Aowei Zhang

International Journal of Physical Activity and Health

Background/Purpose: Five major teaching pain points often occur in the teaching of public physical education courses in universities: (1) First pain point is easy to have deviations in movement cognition and self-practice. (2) It is difficult to accurately grasp the intensity and density of exercise. (3) Lack of process and phased teaching evaluations can inhibit the cultivation of autonomous exercise drive. (4) Unhealthy aesthetics have a negative impact, leading to a deviation in aesthetic perception among students. (5) Students lack autonomous learning ability and have difficulty cultivating post-class exercise habits. How to resolve these "pain points" are now the key …

A040: The Effect Of Blended Online And Offline Physical Education On The Health-Related Indexes Of Undergraduates, Shijun Gong, Aowei Zhang, Dongxiao Liu, Yanxin Liu

International Journal of Physical Activity and Health

Background/Purpose: With the explosive development of artificial intelligence, many scholars have carried out research around the combination of online and offline physical education courses. Current research has focused on developing the application of information technology in the classroom teaching of physical education. The main purpose addressed in this study was to investigate the possible effects of implementing such a blended online and offline physical education at home on the health-related indices of students.

Method: Totally 14,708 college students participated, including 6,125 males and 8,583 females. In the analysis approach, research was adopted using SPSS 26.0, specifically the paired-samples T test …

A046: Recreational Skiing Injury Rate: A Case Study Of A Ski Resort In Central New York, Hongwei Guan, David Guan, Xiaoran Li

International Journal of Physical Activity and Health

Background/Purpose: More people in China are participating in snow sports, especially after the Beijing 2022 Winter Olympics. Despite health benefits, skiing and snowboarding are associated with injury risk. Ski safety and injury prevention are essential for sustainable operation of ski resorts with the rapid development of snow sports in China. The purpose of this study was to examine the injury rate at a popular medium-sized ski resort in Central New York and compare it with that of similar ski resorts in Northeastern China.

Method: Direct ski patrol observation and injury incident reports of three seasons from 2020-21 to 2022-23 were …

A049: Associations Between 24-Hour Accelerometer-Derived Novel Metrics With Health-Related Physical Fitness In Chinese Adolescents, Yanping Qiu, Lijuan Wang, Huan Chen, Xiaoqing Li

International Journal of Physical Activity and Health

Background/Purpose: Time-use estimates are commonly utilized for describing 24-hour movement behaviors. Nonetheless, the average acceleration (AvAcc), intensity gradient (IG) and the most active X minutes (MX metrics) have been proposed as 24-hour movement behaviors novel metrics describing the volume of activity, the intensity distribution and the most active time periods of the 24-h cycle. This cross-sectional study aimed to examine associations between 24-h accelerometer-derived metrics and health-related physical fitness in Chinese adolescents.

Methods: This study recruited 240 students aged 12-18 (143 males, 97 females) from a middle school in Haizhu District, Guangzhou City. The data collection period was from March …

A052: Construction Of Ski Instructors' Competency Evaluation Index System Based On O*Net Working Analysis, Juan Ran, Hongyan Wang

International Journal of Physical Activity and Health

Background/Purpose: Skiing has emerged as a preeminent activity in ice and snow tourism, with ski resorts significantly bolstering the winter tourism economy. However, the burgeoning demand for instructors, coupled with the increasing number of enthusiasts, poses critical challenges for the sport's development. To address these issues, we have undertaken a comprehensive competency assessment to inform the training and retraining of instructors. This evaluation is also pertinent for selecting unlicensed instructors.

Method: The study involved 12 experts and 250 ski instructors from Jilin Province. Research was conducted using keywords such as 'competency model' and 'instructor quality'. The O*NET questionnaire and a …

A055: The Relationship Between Grip Strength And Quality Of Life In The Elderly Based, Fanhao Meng

International Journal of Physical Activity and Health

Background: The World Health Organization (WHO) has launched the "Decade of Healthy Ageing" from 2021 to 2030 to address the challenges of a rapidly ageing global population. The extension of human lifespan is a manifestation of social progress, but aging and increased longevity may be accompanied by problems such as reduced physical and mental abilities and increased risk of diseases, which affects quality of life (QOL). Grip as an indicator of strength and is associated with physical activity in older adults. It is readily applicable in clinical and community settings, and there is an association between grip strength and health-related …

A058: The Impact Of Multi-Directional Training On Change-Of-Direction Speed And Short-Distance Sprint Ability In Tennis Student-Athletes, Ke Zhang, Yue Zhao, Zhihui Zhou, Haijun Wu

International Journal of Physical Activity and Health

Objective: Tennis, characterized by rapid multi-directional sprints, involves lateral movements along the baseline constituting approximately 70% of gameplay, with each single movement covering around 3 meters. On average, there are 2-4 direction changes per point, and each stroke requires 0.4 seconds. Recognizing the imperative need for tennis players to rapidly change direction and execute short-distance sprints, influenced by factors like the ball's trajectory, opponent's movements or disguise movements, this study aimed to investigate the impact of three weeks of multi-directional sprint training on the change-of-direction speed and short-distance sprint ability of tennis student-athletes.

Methods: Nineteen male tennis athletes with an …

A062: Experimental Research Of Impact Of Large-Unit Soccer Teaching On Elementary School Students' Physical Health, Yin Zhao, Ziming Shao

International Journal of Physical Activity and Health

Objective: The "Compulsory Education Curriculum Standards: Physical Education and Health(2022 Edition) in China" explicitly proposes that from grades 3-6, at least one sport from six major specialized sports skills should be chosen for at least 18 class periods of relatively systematic and complete teaching, enabling students to not only master the sports skills of the chosen project but also deepen their comprehensive experience and understanding of the sport. Long-standing issues in elementary school football teaching include superficial teaching depth, isolated and incoherent content, and disconnection between educational stages. There is an urgent need for physical education teachers to organize systematic …

A059: Multidimensional Interpretation And Development Strategies For The International Communication Of Dragon And Lion Dancing, Weiyan Wang, Li Zhou, Cuili Zhai

International Journal of Physical Activity and Health

The dragon and lion dance, as the bright treasure of Chinese traditional sports culture, demonstrates Chinese cultural confidence and distinct national characteristics, serving as an important showcase for China's image. However, the international communication of dragon and lion dance faces numerous challenges, including understanding barriers caused by cultural differences, limitations in promotion scope, uneven overall development levels, and balancing cultural impact with cultural identity. These issues are pertinent to the future development of dragon and lion dance.

After conducting a literature analysis, the historical origins, cultural connotations, and communication processes of dragon and lion dances were systematically examined, laying a …

A063: Electroencephalogram (Eeg) Signal Analysis For College Students' Attention And Meditation Level In Yoga Courses, Zhonghui He, Fangxin Li, Xi Qi, Honglin Chen

International Journal of Physical Activity and Health

PURPOSE: Yoga is associated with psychological and physiological benefits, including relaxation and increased attention. Electroencephalograms (EEG) signals reflect the electrical activity of the brain and transformed Alpha and Beta brainwaves into meditation and attention values. This study primarily aimed to measure college students’ attention and meditation level in yoga courses. The secondary aim was to explore yoga’s effect on students’ cognitive ability.

METHODS: The study selected two yoga classes in the first semester of 2023 in an academic university in China. Using convenience sampling methods, 16 college students who attended yoga courses voluntarily participated in this study. All learning phases, …

A064: An Experimental Study On Pe Teachers' Motivational Style Change On Adolescents' Physical Activity, Zhigang Xue

International Journal of Physical Activity and Health

Research background: Realistic demands: The decline of adolescents' physical health has been the focus of global attention. Current needs: Youth physical activity needs to be improved. Key issue: The interest and motivation of adolescents to participate in physical activity are generally low. Ways to improve: physical education can effectively promote the physical activity of teenagers in their leisure time. It is of great theoretical and practical value to study the integration of planned behavior theory and self-determination theory to explain adolescents' leisure time physical activity behavior to promote physical activity level using physical activity interventions.

Research method: Mainly through the …

A066: Differences In Body Stability During Continuous Turning In Older And Younger Adults, Yulong Bo

International Journal of Physical Activity and Health

Background/Purpose: The deterioration of body stability with age remains an area of interest, particularly in the context of continuous turning during walking among older adults. This study aimed to describe the characteristics of body stability during continuous turning in older and younger individuals, as well as identify potential risk factors, providing a theoretical basis for fall prevention in older adults during continuous turning.

Methods: Fifteen older adults (mean age 69.58 ± 3.84 years) and fifteen younger individuals (mean age 23.93 ± 1.14 years) were recruited from the community. Participants were asked to walk around an 8-shaped continuous turning path (diameter …

A068: A Case Study Of Hippy Family Intervention On Motor Ability In Children With Developmental Delays, Jiayu Zhou, Xiaozan Wang, Qinping Xu

International Journal of Physical Activity and Health

Background: The phenomenon of motor retardation caused by serious insufficient physical activity of children is increasing. Improving the family's parenting knowledge and skills can promote the family's healthy lifestyle and have a positive impact on the healthy development of children.

Method: The children with developmental delays were followed in their natural state for three months, combined with the "HIPPY family intervention model" to improve their family's parenting knowledge and skills, and to intervene in the behavioral performance and physical activity of children with motor development delays.

Results: After 3 months of HIPPY family intervention, TGMD showed an overall upward trend, …

A070: Research On The Promotion Strategy Of Sports Tourism Consumption Based On Consumer Evaluation, Wang Yan, Jinsheng Liu

International Journal of Physical Activity and Health

Background/Purpose: Recently, challenges coupled with constraints such as shrinking demand and weakening consumption expectations have greatly increased the complexity and vulnerability of the internal and external environment of the sports tourism consumption system. Consumer evaluation is an important way of consumption decision-making reference and information exchange, which affects consumers' purchase decision, consumption experience, habits and attitude. Sports tourism boutique project is a consumption project and key consumption content with sports tourism characteristics. The purpose of this study was to conduct an analysis of the consumption evaluation of specific Chinese sports tourism boutique projects through the user evaluation data from Ctrip …

A073: Factors Affecting Continuous Use Of Metaverse-Based Sports Products: Based On Perceived Value, Enjoyment, And Immersion, Qiao Yang, Aisha Wang

International Journal of Physical Activity and Health

Purpose: Metaverse technology has introduced a new era of sports interaction, offering users an extraordinary virtual environment for immersive experiences. However, there is still a lack of comprehensive understanding regarding the determinants of continuous use in metaverse-based sports products. This study aimed to delve into the factors influencing the continuous use of sports products based on the metaverse.

Methods: To collect data for this study, an online questionnaire survey was conducted among Chinese digital natives residing in major cities (Beijing, Shanghai, Guangzhou, and Shenzhen) who frequently used metaverse-based sports products. A total of 634 participants were collected, of which 520 …

A083: Effects Of Muscle Energy Technique On Neuromuscular Function In Patients With Non-Specific Lower Back Pain, Zhipeng Zhou, Jianbin Zhao

International Journal of Physical Activity and Health

Background/Purpose: Non-specific lower back pain (NLBP) is one of the most common causes of disability worldwide. In patients with NLBP, reduced lumbar flexion-relaxation and reduced variability of muscle activity distribution are reported as abnormal muscle activity. Muscle energy technique (MET) is used to be a conservative, non-pharmacological treatment method for somatic dysfunctions of the musculoskeletal system. However, the effect of MET approach on the flexion-relaxation phenomena (FRP) is unclear. Therefore, the purpose of this study was to investigate the effects of MET on pain, lumbar function, and FRP in patients with NLBP.

Methods/Design: Thirty patients with NLBP were randomized into …

A082: Theoretical Deconstruction And Value Implication Of Physical Participation Of Fitness Group Under Field Theory, Mengyu Huo, Pengfei Gao, Guangbin Bai, Xinyan Shi, Chongqing Hu, Ruidi Wang

International Journal of Physical Activity and Health

Research background: In the transformation of consumer society, the body is gradually regarded as an important symbol. People are often willing to consume for the body in different ways to seek the shaping of body image. Therefore, the value of body shaping through sports has been gradually paid attention to, and "Fitness fever" has gradually become a new fashion. Based on this, Pierre Bourdieu's social practice theory makes a rational interpretation of the participation behavior of individual actors in the field of sports and analyzes the value correlation between individual sports behavior and society, which is another important consideration for …

A088: Virtual And Real: An Exploration Of The Body Sense Of Generation Z E-Sports Players, Yuxin Luo, Xianglin Luo, Lu Liu

International Journal of Physical Activity and Health

Background：The advent of eSports has catalyzed a fresh wave of contemplation within the sports science community regarding the concept of the body. With the digital revolution, eSports has emerged as a significant segment within the realm of sports, further solidified by its recognition in prestigious events like the Asian Games. However, despite its elevated status, eSports continues to grapple with skepticism over its 'non-physical' nature due to the apparent lack of physical activity that characterizes traditional sports. Exploring Generation Z's experiences in eSports enhances our grasp of digital gaming's corporeal aspects and unveils complex ties between the body, eSports, …