Medicine and Health Sciences Commons^™

The Running Performance Of Elite Ladies Gaelic Football With Respect To Position And Halves Of Play, Shane Malone, Aideen Mcguinness, John David Duggan, Amy Murphy, Kieran Collins, Cliodhna O'Connor

Articles

The current investigation aimed to examine the running performance of elite Ladies Gaelic football (LGF) match-play and establish the within game positional profile, in addition to the running performance of players across halves of play.

Methods

GPS technology was used to examine the running performance of thirty-three (n = 33) elite LGF players (age; 23 ± 5 years, height; 173 ± 5 cm, body mass; 63 ± 4 kg). Across the duration of the observational period, one hundred and thirty-one (n = 131) individual samples were collected over 15 competitive matches. Data were classified based on positional line …

Enzymatic Electrochemical Biosensors For Neurotransmitters Detection: Recent Achievements And Trends, Zina Fredj, Baljit Singh Dr., Mohamed Bahri, Peiwu Qin, Mohamad Sawan

Articles

Neurotransmitters (NTs) play a crucial role in regulating the behavioral and physiological functions of the nervous system. Imbalances in the concentrations of NT have been directly linked to various neurological diseases (e.g., Parkinson’s, Huntington’s, and Alzheimer’s disease), in addition to multiple psychotic disorders such as schizophrenia, depression, dementia, and other neurodegenerative disorders. Hence, the rapid and real-time monitoring of the NTs is of utmost importance in comprehending neurological functions and identifying disorders. Among different sensing techniques, electrochemical biosensors have garnered significant interest due to their ability to deliver fast results, compatibility for miniaturization and portability, high sensitivity, and good controllability. …

Cardiorespiratory And Metabolic Responses To Low-Intensity Blood-Flow Restricted Running, Violet E. Sullivan, Amanda P. Ares, Summer B. Cook Ph.D.

Honors Theses and Capstones

Low-intensity (LI) aerobic exercise with blood-flow restriction (BFR) increases heart rate (HR), oxygen consumption (VO₂), and ratings of perceived exertion (RPE), sometimes to similar levels as high-intensity (HI) exercise. Distance runners may benefit from LI-BFR running in periods of reduced volume or intensity, possibly due to injury. PURPOSE: To compare HR, VO₂, blood lactate (BLa), and RPE during LI-BFR running and HI running without BFR. METHODS: Fifteen female distance runners (age 23+4yrs, height 1.67+0.50m, body mass 57.6+5.7kg, VO₂max 51.0+4.5mL•kg^-1•min^-1) completed three randomized 12-minute running conditions: LI control (40% VO_{2 …}

Implementing Universal Suicidality Screening In A Critical-Access Emergency Department, Delaney M. Kjendal, Kerry Nolte, Sara Robinson, Kimberly Force

Honors Theses and Capstones

Background: Implementation of a universal suicidality screening is considered best practice as it is associated with improved the detection of occult, or latent, suicide risk and can reduce subsequent risk. This quality improvement (QI) project evaluates the implementation of the Columbia-Suicide Severity Rating Scale (C-SSRS) to screen patients over the age of twelve at a regional healthcare system.

Methods: The QI project was conducted at Littleton Regional Healthcare (LRH) emergency department, a critical-access hospital in Littleton, New Hampshire that serves about 206 patients per week. Implementation of suicidality screening was of interest to LRH to promote mental health in the …

Intentional Misdiagnosis And Ethical Considerations Of Mental Health Counselors Working With Managed Care, Emily Lake

Dissertations and Theses

Abstract Research has discussed ethical dilemmas for professional counselors working with managed care. Professional counselors are faced with the implications of providing a diagnosis to clients to receive reimbursement by managed care and to assist clients in receiving care. The purpose of the study is to better understand the counselor’s role in intentional misdiagnosis due to billing requirements from insurance companies. Furthermore, the researcher is interested in the personal and professional characteristics of counselors predictive of the decision to engage in intentional misdiagnosis. Participants in this study were asked to complete the Marlowe-Crowne Social Desirability Scale and a researcher-created survey. …

Serum Neurofilament Light-Chain Levels And Long-Term Treatment Outcomes In Relapsing-Remitting Multiple Sclerosis Patients: A Post Hoc Analysis Of The Randomized Combirx Trial, Gary Cutter, Richard A Rudick, Carl De Moor, Carol M Singh, Elizabeth Fisher, Thijs Koster, Fred D Lublin, Jerry S Wolinsky, Henry Mcfarland, Steven Jacobson, Maria L Naylor

Faculty, Staff and Student Publications

BACKGROUND: CombiRx was a randomized, double-blind, placebo-controlled phase 3 trial in treatment-naive relapsing-remitting multiple sclerosis (RRMS) patients randomized to intramuscular interferon beta-1a (IM IFN beta-1a), glatiramer acetate (GA), or both therapies.

OBJECTIVE: This analysis investigated changes in serum neurofilament light-chain (sNfL) levels in response to treatment and assessed baseline sNfL as a predictor of relapse.

METHODS: RRMS patients treated with IM IFN beta-1a 30 µg weekly + placebo (n = 159), GA 20 mg/mL daily + placebo (n = 172), or IM IFN beta-1a + GA (n = 344) were included. A linear mixed model compared sNfL values over time. …

Groundwater Quality: Global Challenges, Emerging Threats And Novel Approaches, Dan Lapworth, Thomas Boving, Bentje Brauns, Jane Dottridge, Paul Hynds, Seifu Kebede, David Kreamer, Bruce Misstear, Abhijit Mukherjee, Abhijit Mukherjee, Viviana Re, James Sorensen, Claudia Ruz Vargas

Articles

Improving our understanding of groundwater quality threats to human health and the environment is essential to protect and manage groundwater resources effectively. This essay highlights some global groundwater quality challenges, describes key contaminant groups and threats of emerging concern, including antimicrobial resistance, and discusses novel approaches to assessing groundwater quality. Groundwater quality monitoring needs to improve significantly in order to effectively identify and mitigate threats to groundwater from historical, current and future pollution.

Quantifying Farm-To-Fork Greenhouse Gas Emissions For Five Dietary Patterns Across Europe And North America: A Pooled Analysis From 2009 To 2020, Daniel Burke, Paul Hynds, Anushree Priyadarshini

Articles

Dietary patterns are inherently related to greenhouse (GHG) emissions via agricultural practices and food production systems. As the global population is predicted to increase from 8 billion (current) to 9.6 billion by 2050 added pressure will be placed on existing agricultural systems, resulting in increased GHG emissions thus exacerbating climate change. Therefore, there is an urgent need to understand present-day dietary patterns to shift to sustainable and healthy diets to mitigate GHG emissions and meet future climate targets. However, no review or pooled analyses of dietary pattern emissions from a farm-to-fork perspective has been undertaken to date. The current study …

Integrating Consumer Risk Perception And Awareness With Simulation-Based Quantitative Microbial Risk Assessment Using A Coupled Systems Framework: A Case Study Of Private Groundwater Users In Ontario, Tessa Latchmore, Sarah Lavallee, Paul Hynds, R. Stephen Brown R. Stephen Brown, Anna Majury

Articles

Private well users in Ontario are responsible for ensuring the potability of their own private drinking water source through protective actions (i.e., water treatment, well maintenance, and regular water quality testing). In the absence of regulation and limited surveillance, quantitative microbial risk assessment (QMRA) represents the most practical and robust approach to estimating the human health burden attributable to private wells. For an increasingly accurate estimation, QMRA of private well water should be represented by a coupled model, which includes both the socio-cognitive and physical aspects of private well water contamination and microbial exposure. The objective of the current study …

Assessing The Risk Of Acute Gastrointestinal Illness Attributable To Three Enteric Pathogens From Contaminated Private Water Wells In Ontario, Tessa Latchmore, Paul Hynds, R. Stephen Brown, Kevin Mcdermott, Anna Majury

Articles

The province of Ontario compromises the largest groundwater reliant population in Canada serving approximately 1.6 million individuals. Unlike municipal water systems, private well water is not required to meet water quality regulatory standards and thus source maintenance, treatment and testing remains the responsibility of the well owner. Infections associated with private drinking water systems are rarely documented given their typically sporadic nature, thus the human health effects (e.g., acute gastrointestinal illness (AGI)) on consumers remains relatively unknown, representing a significant gap in water safety management. The current study sought to quantify the risk of waterborne AGI attributed to Giardia, shiga-toxin …

Occurrence Of High-Risk Clonal Lineages St58, St69, St224, And St410 Among Extended-Spectrum-Lactamase-Producing Escherichia Coli Isolated From Healthy Free-Range Chickens (Gallus Gallus Domesticus) In A Rural Region In Tunisia, Saloua Benlabidi, Anis Raddaoui, Sana Lengliz, Sarah Cheriet, Paul Hynds, Wafa Achour, Taoufik Ghrairi, Mohamed Salah Abbassi Salah Abbassi

Articles

Antimicrobial-resistant Escherichia coli isolates have emerged in various ecologic compartments and evolved to spread globally. We sought to (1.) investigate the occurrence of ESBL-producing E. coli (ESBL-Ec) in feces from free-range chickens in a rural region and (2.) characterize the genetic background of antimicrobial resistance and the genetic relatedness of collected isolates. Ninety-five feces swabs from free-range chickens associated with two households (House 1/House 2) in a rural region in northern Tunisia were collected. Samples were screened to recover ESBL-Ec, and collected isolates were characterized for phenotype/genotype of antimicrobial resistance, integrons, and molecular typing (pulsed-field gel electrophoresis (PFGE) and multilocus …

Unintended Consequences Of Covid-19 Non-Pharmaceutical Interventions (Npis) For Population Health And Health Inequalities, Coilin Ohaiseadha, Gerry A. Quinn, Ronan Connolly, Awwad Wilson, Michael Connolly, Willie Soon, Paul Hynds

Articles

Since the start of the COVID-19 pandemic in early 2020, governments around the world have adopted an array of measures intended to control the transmission of the SARS-CoV-2 virus, using both pharmaceutical and non-pharmaceutical interventions (NPIs). NPIs are public health interventions that do not rely on vaccines or medicines and include policies such as lockdowns, stay-at-home orders, school closures, and travel restrictions. Although the intention was to slow viral transmission, emerging research indicates that these NPIs have also had unintended consequences for other aspects of public health. Hence, we conducted a narrative review of studies investigating these unintended consequences of …

Identifying Novel Data-Driven Dietary Patterns Via Dimensionality Reduction And Associations With Socioeconomic Profile And Health Outcomes In Ireland, Daniel Burke, Annemarie E. Bennett, Paul Hynds, Anushree Priyadarshini

Articles

Dietary patterns and body mass index (BMI) play a significant role in the development of noncommunicable diseases (NCDs), which are the leading cause of mortality worldwide, including Ireland. A cross-sectional survey was conducted across Ireland to collate respondents’ socioeconomic profiles, health status, and dietary patterns with a representative sample size of 957 adult respondents. Principal component analysis (PCA) and statistical analyses were subsequently employed. To the author’s knowledge, this is the first study to use recent (2021) nationally representative data to characterise dietary patterns in Ireland via dimensionality reduction. Five distinct dietary patterns (“meat-focused”, “dairy/ovo-focused”, “vegetable-focused”, “seafood-focused”, and “potatofocused”) were …

Behavioral Pathways To Private Well Risk Mitigation: A Structural Equation Modeling Approach, Simon Mooney, Martin Boudou, Jean O'Dwyer, Paul Hynds

Articles

Complex, multi hazard risks such as private groundwater contamination necessitate multiannual risk reduction actions including seasonal, weather-based hazard evaluations. In the Republic of Ireland (ROI), high rural reliance on unregulated private wells renders behavior promotion a vital instrument toward safeguarding household health from waterborne infection. However, to date, pathways between behavioral predictors remain unknown while latent constructs such as extreme weather event (EWE) risk perception and self-efficacy (perceived behavioral competency) have yet to be sufficiently explored. Accordingly, a nationwide survey of 560 Irish private well owners was conducted, with structural equation modeling (SEM) employed to identify underlying relationships determining key …

Optimisation Of Raman Spectral Processing For Classification Of Radiotherapeutic Toxicity, Isha Behl, Dinesh Medipally, Chris Talbot, Aidan Meade, Fiona Lyng

Conference papers

Severe radiation toxicity can continue years after the completion of radiotherapy for prostate cancer patients. Currently, it is impossible to predict before treatment which patients will experience these long-term side effects. New approaches based on vibrational spectroscopy have advantages over lymphocyte and genomic assays in terms of minimal sample preparation, speed and cost. A high throughput method has been developed to measure Raman spectra from liquid plasma in a cover glass bottomed 96 well plate. However, the Raman spectra can show contributions from glass and water. The current study aims to optimise pre-processing steps to improve classification performance.

Identification Of Precancerous Oral Lesions Using Minimally Invasive Sampling Techniques And Raman Microspectroscopy, Isha Behl

Conference papers

The gold standard diagnosis of oral pre-cancer/cancer is an invasive biopsy followed by a histological examination, which may present psychological trauma and risk of infection to patients. Moreover, multiple biopsies are often required to monitor precancer lesions' progression. With the aim of reducing the need for multiple biopsies, this study was undertaken to identify pre-cancerous lesions using minimally invasive brush biopsy and saliva samples, analysed by Raman spectroscopy.

Raman Spectroscopy For Early Detection Of Cervical Cancer, A Global Women’S Health Issue—A Review, Rubina Shaikh, Amuthachelvie Daniel, Fiona Lyng

Articles

This review focuses on recent advances and future perspectives in the use of Raman spectroscopy for cervical cancer, a global women’s health issue. Cervical cancer is the fourth most common women’s cancer in the world, and unfortunately mainly affects younger women. However, when detected at the early precancer stage, it is highly treatable. High-quality cervical screening programmes and the introduction of the human papillomavirus (HPV) vaccine are reducing the incidence of cervical cancer in many countries, but screening is still essential for all women. Current gold standard methods include HPV testing and cytology for screening, followed by colposcopy and histopathology …

Natural History Of Occult Hernias In Adults At A Safety-Net Hospital, Duyen Quach, Kayla Nguyen, Nicole Lyons, Oscar Olavarria, Karla Bernardi

Gulf Coast Division GME Research Day 2023

No abstract provided.

The Re-Emergence Of An Ancient Disease: A Case Presentation Of Spinal Tuberculosis, Danay Herrera, Nargisa Ergasheva, Paola Solari, Daniel Kaswan, Bryan Greendield

East Florida Division GME Research Day 2023

Please see supplemental content for full abstract with references.

Introduction: An ancient disease identified in Egyptian and Peruvian mummies, tuberculous spondylitis caused by Mycobacterium tuberculosis (MTB) is considered the most common form of extrapulmonary tuberculosis (TB) [1,5]. Despite the identification of the causative agent, the improvement in diagnostic tools, the production of the Bacillus Calmette-Guerin (BCG) vaccine, and the development of antimicrobial regimens since the disease was first described, it remains a major health burden today with significant morbidity and mortality among developing countries [5]. Spinal TB can lead to severe deformity and permanent neurological deficits, as such early recognition …

Two Paes In A Pod, Jennifer Horawski, Mina Guirguis, Andrew Baird, Thomas Chambers

South Atlantic Division GME Research Day 2023

No abstract provided.

Amiodarone-Induced Thyrotoxicosis Type 2 : Utilization Of Color-Flow Doppler Sonography For Diagnosis, Sam Joseph, Larissa Check, Donald Eagerton

South Atlantic Division GME Research Day 2023

No abstract provided.

Raptir: Retroclavicular Approach To The Infraclavicular Region, Casey Wilson, Jacob Pope, David Pardue, Thomas Thornton

South Atlantic Division GME Research Day 2023

No abstract provided.

Endobronchial Ultrasound Diagnosis Of A Malignant Superior Vena Cava Tumor Thrombus Extending Into The Right Atrium: An Unusual Cause Of Recurrent Syncope., Larissa Check, Ariba Naz, Richard Duff

South Atlantic Division GME Research Day 2023

No abstract provided.

Hospitalization Of A Healthy Young Man Following Daily Loperamide Use At Near Therapeutic Doses, Steven Sprenger, Sarah Marks, Alan Lynch

TriStar Division Research Day 2023

No abstract provided.

Care Alert Program In Chronic Recurrent Ed Utilizing Patients: Expanded Study, Jonathan Leggett, Kaitlyn Phelps, Erica Gibbons, Jonathan Bryan, Brent Wright, Daniel Nunez, Brian Griggs

South Atlantic Division GME Research Day 2023

No abstract provided.

Congenital Mesenteric Defect Results In Internal Hernia In An Adult With Obstructed Small Bowel, Tameem Jamal, Adina Mcnair, Saptarshi Biswas

South Atlantic Division GME Research Day 2023

No abstract provided.

Musculoskeletal Lecture Series: Neck Pain, Ryan Brown, Pradeep D'Souza, Ryan Giang

Gulf Coast Division GME Research Day 2023

No abstract provided.

Crochetage Pattern: An Electrocardiographic Warning Sign For Scuba Divers, Sarah Crawford

West Florida Division GME Research Day 2023

No abstract provided.

Opioid-Induced Intrathecal Catheter Tip Granuloma Via Pain Pump In A Patient With Chronic Pain Syndrome: A Case Report, Katherine David, R Blake Kline, Jon Halling

South Atlantic Division GME Research Day 2023

No abstract provided.

Seeing Is Believing: Implementation Of An Usgpiv Training Curriculum In Pediatric Medical Providers, Matthew Toma, Allyn Parker, Sunil Keshwah

South Atlantic Division GME Research Day 2023

No abstract provided.