Medicine and Health Sciences Commons^™

Enhanced Central Sympathetic Tone Induces Heart Failure With Preserved Ejection Fraction (Hfpef) In Rats, Shyam S. Nandi, Kenichi Katsurada, Michael J. Moulton, Hong Zheng, Kaushik K. Patel

Journal Articles: Cellular & Integrative Physiology

Heart failure with preserved ejection fraction (HFpEF) is a heterogenous clinical syndrome characterized by diastolic dysfunction, concentric cardiac left ventricular (LV) hypertrophy, and myocardial fibrosis with preserved systolic function. However, the underlying mechanisms of HFpEF are not clear. We hypothesize that an enhanced central sympathetic drive is sufficient to induce LV dysfunction and HFpEF in rats. Male Sprague-Dawley rats were subjected to central infusion of either saline controls (saline) or angiotensin II (Ang II, 20 ng/min, i.c.v) via osmotic mini-pumps for 14 days to elicit enhanced sympathetic drive. Echocardiography and invasive cardiac catheterization were used to measure systolic and diastolic …

Identification Of Two Potential Small-Molecules That Inhibit The Cd155/Tigit Pathway In Human Astrocytoma, Ahmed Qandouci, Khadija El Azhary, Sanaa Souat, Abdallah Badou

Health Sciences

Astrocytoma represents a malignant brain tumor. Therapeutic strategies, including immunotherapy, are in continuous development to ameliorate the overall survival. Several immune checkpoints like CD155 and TIGIT were explored for this purpose. Still, the specific mAb against these molecules showed very limited outcome, which supports the need of investigating other strategies to block this pathway such as small-molecules drugs. In this study, bioinformatics approaches were used to answer our question. First, TCGA database was explored to evaluate the implication of CD155 and TIGIT in the progression of malignant astrocytoma. Then CIBERSORT analysis was used to analyze the difference of immune infiltration …

Medical Professors’ Perception Of E-Learning During Covid19 Period, Mounia Bendari, Hanane Delsa, Fadila Guessous, Said Benchekroun

Health Sciences

Over the past few years, our lives have been deeply impacted by technological innovations. Educational programs have also integrated a technological method for learning. This new entity has been called electronic learning (E-learning).

At Mohammed VI University of Health and Sciences, students benefitted from the E-learning for quite a few years now, but the pandemic of Sars-CoV2 was an opportunity for our university to apply increased optimization in the use of the technological methods that we have to make it possible for staff to quickly and efficiently implement tools for adaptation to the circumstances of Sars-Cov2. These adaptations also assured …

Artificial Intelligence In Dentistry : Knowledge And Perceptions Of Moroccan Students, Manal Elhijazi, Ihsane Benyahya

Health Sciences

Introduction: Artificial intelligence (AI) is a revolution in education, research and health. The aim of this study is to assess the views and perceptions of dental students regarding artificial intelligence and its impact on their future professional practice. Methods: A voluntary anonymous e-questionnaire was sent to all 4th and 5th year dental students of the Faculty of Dentistry after receiving a course on artificial intelligence. The questionnaire consisted of sections to assess students' knowledge of artificial intelligence and its possible applications in dentistry as well as ethical considerations. Statistical analysis of the data was carried out using SPSS version 23 …

Prepubertal Periodontitis In Children: For An Adequate Diagnosis And Optimal Care, F.Z. El Mouatarif, S. Chemlali, M. Hamza, J. Kissa, S. El Arabi

Health Sciences

Prepubertal periodontitis (PP) is a rare and rapid progressive condition found a young cohort of patients that results in destruction of the periodontal support of the primary dentition. Its generalized form, prepubertal periodontitis is often associated with a significant gingival tissue inflammation and fast bone loss with attachment loss leading to the tooth loss. The localized form of PP is characterized by a much more discreet inflammation and slow evolution. It can be associated with a known underlying systemic disease or may occur as part of a recognized syndrome or as an isolated finding. Different treatment modalities can be used …

Biological Parameters And The Histological Response In Rectal Cancer Treated By Neoadjuvant Chemoradiotherapy: A Moroccan Cohort, A. Naim, N. Bouanani, F. Safini, S. Mounaime, Soumaya Rafii, L. Lachker, F. Guessous, M. Khaliss, N. Tawfiq, A. Badou

Health Sciences

Introduction: Multimodal management of rectal cancer, combining neoadjuvant Radio chemotherapy followed by total Mesorectal therapy (TME), has been shown to improve locoregional control. However, the histological response is variable independently of the initial tumor stage. Some recent data suggest the usefulness of the lymphocyte-monocyte ratio (LMR), neutrophil-lymphocyte ratio (NLR), and platelet-lymphocyte ratio (PLR) in predicting the histological response to neoadjuvant therapy. This study aimed to investigate the correlation between the complete histological response (pCR) after neoadjuvant radio chemotherapy and biological parameters (LMR, NLR and PLR) in rectal cancer patients.

PATIENTS AND METHODS: This retrospective study was conducted in three Moroccan …

National Children’S Dental Health Month - Sample Newspaper Articles (2023), American Dental Association Foundation

National Children's Dental Health Month

No abstract provided.

Advanced Practice Registered Nurses And Healthcare Disparities: Understanding The Impact Of Implicit Bias, Marla Lepley-Starr

Doctor of Nursing Practice Projects

Introduction: Disparities in healthcare have long been a challenge for physicians, advanced practice providers, nurses, and other interdisciplinary team members. More recently, population health-focused efforts have been implemented to manage everincreasing rates of diabetes, hypertension, and obesity, as well as lack of transportation, limited access to care, and poverty (North Carolina Department of Health and Human Services [NCDHHS], 2019). Racism, sexism, ageism, sizeism, etc., are present in the healthcare setting and manifests in implicit bias during care delivery. This can manifest as beliefs, behaviors/practices, and emotions of the provider (Paradies et al., 2014). Research is limited related to the …

Occupational Therapy’S Role In Addressing The Intersectionality Of Veterans Who Are Chronically Homeless, Mental Health, And Sleep Deprivation, Maci Bakken, Abby Eken, Morgan Halliday

Critically Appraised Topics

Currently, there are interventions available for rest and sleep for the general population. However, those interventions do not usually address the unique needs of the population of veterans who are homeless with mental health disorders. While there is information on the person, environmental, and occupational factors surrounding this topic separately, there is limited literature regarding how to address all of these factors when they transact with each other. The purpose of this critically appraised topic paper is to examine the impacts that being a veteran, having a mental health disorder, and being homeless have on sleep deprivation as well as …

Perception Of Workload And Task Importance During Complex And Dual Task Conditions, Alicia Maul, Cody Lamont, Erin Zurbrugg, Gillian Berry, Katherine Armstrong, Lea Keenantasker, Patricia Eckart, Cindy Zablotny, Theresa Raudsepp, Ryan Jacobson

Student-Faculty Research - College of Physical Therapy

Background

• "cognitive processes and movement need to occur concurrently as part of social engagement; voluntary movement is not wholly automatic and when movement occurs, it leads to changing cognitive demands." (McIsaac et al, 2015)

• Current practice for creating dual-task challenges in the clinic include serial subtraction and carrying a glass of water (complex walking task) however these do not always translate to a patient's individualized challenges and goals

• Research has shown that a patient's engagement and performance improves when the task they are performing is meaningful in their lives. (McIsaac et al, 2015)

• Would including items …

Effects Of A Parkinson's Disease Community Exercise Group On Self Reported Promis Measures, Desiray Anderson, Alexis Creighton, Jillian Studer, Tyler Cuddeford

Student-Faculty Research - College of Physical Therapy

Parkinson’s Disease (PD) is an upper motor neuron disorder that results in bradykinesia, rigidity, shuffling gait patterns, and balance impairments. Non-motor issues include depression, anosmia, GI issues, pain, and more. Approximately 90,000 people in the U.S. are diagnosed every year.

Hypothesis: Self efficacy and satisfaction roles will positively correlate with participation in the 6 week exercise program.

Research News, Publications, 2023, Volume 1, Soumyajit Majumdar

Publications (2015-)

Publications that appeared during the period of January 1 through March 31, 2023

Covid Remains 2023, Sheila P. Davis

Journal of Health Ethics

Editor's introduction to Vol. 19, Issue 1 of the Journal of Health Ethics

Mycotic Aneurysm A Rare Complication From Infection Masquerading As Lung Cancer, Rithvik Nallapareddy, Md, Mary Anne Nidiry, Md

Poster Presentations

No abstract provided.

Benefits Of Rooming-In On Infants With Neonatal Opioid Withdrawal Syndrome, Emma Ricioli

Nursing | Senior Theses

Neonatal opioid withdrawal syndrome (NOWS) is a significant public health concern, affecting infants born to mothers who use opioids during pregnancy. Those exposed in-utero exhibit numerous signs of withdrawal after delivery including tremors, gastrointestinal distress, inconsolability, and poor feeding. Typical treatment for infants suffering from NOWS included direct admission to the neonatal intensive care unit (NICU) for close observation and pharmacological interventions. However, NICU stays can interfere with bonding and breastfeeding. They can also lead to increased lengths of stay, higher costs, and more invasive pharmacological treatments. These infants typically do not have any other concerning health issues besides NOWS …

Examining The Effects Of Music Therapy On Physical And Psychological Symptoms Among Cancer Patients Undergoing Chemotherapy, Guadalupe Saldana

Nursing | Senior Theses

Background: Patients undergoing chemotherapy experience undesirable physical and psychological effects in which medications are the preferred method of management. However, standard medications are often insufficient for patients. Failure to attend to the adverse effects can lead to worsening of the patient’s cancer diagnosis and quality of life. The importance of managing chemotherapy symptoms creates an urgent need to implement an approach that is noninvasive, non-pharmacological, and one that still meets the physical and psychological needs of patients receiving chemotherapy.

Objective: The purpose of this thesis is to examine the effects of music therapy (MT) on physical and psychological …

Table Of Contents—Masthead

International Journal of Transpersonal Studies

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In This Issue Of Ijts

International Journal of Transpersonal Studies

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Mathematical Calculations For The Finality Of Death? The Drake-S Equation, Glenn Hartelius

International Journal of Transpersonal Studies

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The Varieties Of Afterlife Experience: Epistemological And Cultural Implications, Everton De Oliveira Maraldi

International Journal of Transpersonal Studies

When parapsychologists talk about survival, they are usually implying personal survival, that is, a process in which memories, motivations, and personality characteristics of a given person somehow persist after bodily death. Are there other conceptions of survival (and of personal identity) that deserve further scientific examination? My purpose with this brief commentary is to expand on Rock et al’s approach by urging survivalists to discuss and investigate further the many different conceptions of (and explanations for) survival. I propose we critically reflect on our theoretical assumptions and their epistemological and cultural consequences.

Psi-Entific Approach To Post-Mortem Survival: Employing The Multiple Sources Of Psi (Msop) And Discarnate Psi Hypotheses In The Calculation Of A Drake-S Equation, Serge Merlin

International Journal of Transpersonal Studies

The continued investigations of the paranormal facilitated the development of novel theories and methodologies. Psi functioning of the living and the deceased in survival phenomena suggested the living agent psi (LAP) and discarnate psi hypotheses, but neither has demonstrated sufficient explanatory power to claim superiority in explaining survival data. Mediumship studies cannot determine whether paranormal information is sourced by means of discarnate psi or LAP, presenting the source-of-psi problem. Anomalous information can be obtained from joint sources (LAP, survival, or some other source), which supports the multiple sources of psi (MSoP) hypothesis. The maximized explanatory potential of the MSoP hypothesis …

Review Of: The Myth Of Normal-Trauma, Illness, And Healing In A Toxic Culture, By Gabor Maté And Daniel Maté, Nicholas Grant Boeving

International Journal of Transpersonal Studies

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Mindfulness Traps And The Entanglement Of Self: An Inquiry Into The Regime Of Mind, Richard Dixey, Ronald E. Purser

International Journal of Transpersonal Studies

Mindfulness meditation can provide salutary therapeutic benefits, as well as lead advanced practitioners to states of calm and equanimity. In this paper, we argue that such forms of meditation may subtly entrap practitioners in circular, self-reflexive feedback loops. Because these meditation traps fail to clearly discern the operations of mind, they offer a temporary oasis of peace within an unaltered dualistic realm of mind that leaves the root delusion of self-identity intact. Drawing upon Tarthang Tulku’s seminal book Revelations of Mind, we present what he refers to as the “regime of mind,” the processes of cognition, identification and re-cognition in …

Book Review: The Way Of Psychosynthesis, By Petra Guggisberg Nocelli, Catherine Ann Lombard

International Journal of Transpersonal Studies

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Radiation Oncology: Breast Cancer, Julia Hornberger

Student Research Poster Presentations 2023

Radiation Oncology: Breast Cancer

Student Researcher: Julia Hornberger

Faculty Advisor: Dr. Elaine Halesey, Ed.D., R.T.(R)(QM)(ARRT)

Abstract

This project explains breast cancer and the role of radiation therapy. Breast cancer is the most commonly diagnosed malignancy in the world for women. Types of breast cancers, the pathology and risk factors associated, the signs and symptoms, imaging, simulation setup, diagnosis, and treatment, as well as some general statistics and prevention are discussed. In 2022, 280,000 new cases of breast cancer occurred with 40,000 deaths occuring. Breast cancer should be known as it effects 1 in 8 women are diagnosed within their lifetime. …

Effectiveness Of Internet Based Treatment Methods For Symptom Management Of Vestibular Disorders: A Systematic Review, Nina Acosta, Rowan Pepe, Samantha Pavolko, Morgan Carline, Devin Conlon

Student Research Poster Presentations 2023

Introduction: The objective of this systematic review is to investigate the effectiveness of internet-based and blended therapy for patients with peripheral, central, or mixed vestibular dysfunction based on current research.

Methods: Medline, CINAHL Complete, PubMed, and The Cochrane Library were searched from September 2022 to January 2023 using the search terms “vestibular,” “internet,” “computer,” “management,” “online,” “self-efficacy,” “vestibular disorder,” “rehabilitation,” “treatment,” “dizziness,” and “phys* ther*.”Studies were included if they used internet-based interventions for patients with diagnosed vestibular dysfunction caused by pure vestibular pathology. Three independent reviewers performed the selection process based on title, abstract, and full-text reading. In total, 8 …

Incorporating Culinary Medicine Into A First Year Science Course, Elizabeth Merz, Sarah Bultje, Luke Witvliet, Amy Wilstermann, Kumar Sinniah

Summer Research

• Culinary medicine uses an evidence-based approach to translate nutrition research into practical use in order to bring medicine and cooking together 1
• Medical schools are bringing in culinary medicine programs so that prehealth students can relate to their patients in the clinical setting when sharing necessary dietary changes
• Obesity is one of the leading risk factors for early death – From 1990 to 2017, globally, deaths due to obesity has increased by 78%2
• By introducing culinary medicine at the undergraduate level into a first year course, we hope to track the students in the course throughout their four years at …

A Critical Role For Staphylococcal Nitric Oxide Synthase In Controlling Flavohemoglobin Toxicity, Ryan M. Singh, Sujata S. Chaudhari, Sasmita Panda, Elizabeth H. Hutfless, Cortney E. Heim, Dhananjay Shinde, Abdulelah A. Alqarzaee, Margaret F. Sladek, Vineet Kumar, Matthew C. Zimmerman, Paul D. Fey, Tammy Kielian, Vinai Chittezham Thomas

Journal Articles: Cellular & Integrative Physiology

Most coagulase-negative staphylococcal species, including the opportunistic pathogen Staphylococcus epidermidis, struggle to maintain redox homeostasis and grow under nitrosative stress. Under these conditions, growth can only resume once nitric oxide (NO) is detoxified by the flavohemoglobin Hmp. Paradoxically, S. epidermidis produces endogenous NO through its genetically encoded nitric oxide synthase (seNOS) and heavily relies on its activity for growth. In this study, we investigate the basis of the growth advantage attributed to seNOS activity. Our findings reveal that seNOS supports growth by countering Hmp toxicity. S. epidermidis relies on Hmp activity for its survival in the host under NO stress. …

Professional Behaviors On The Fieldwork Performance Evaluation: Perspectives Of Fieldwork Educators, Jessi S. Clark

Occupational Therapy Doctorate Capstone Projects

Occupational therapy (OT) students are assessed on their professional behavior skills during Level II fieldwork (FW) by fieldwork educators (FWEs) as measured by the Fieldwork Performance Evaluation (FWPE). Most of these professional behavior skills are not required components of entry-level OT education, therefore academic preparation may be variable. The purpose of this Capstone project was to study the perspective of FWEs regarding the seven professional behavior items on the FWPE, primarily the relative importance of and academic preparation for these items. Participants included FWEs who completed the FWPE in the last 15 years. They completed an online survey that utilized …

Improving Osteoporosis Awareness By Implementing Bone Mineral Density (Bmd) Testing Algorithm, Mark A. Roark

Doctor of Nursing Practice Projects

One of the leading concerns in the United States healthcare system is the aging population and age-related health concerns such as osteoporosis. Estimates suggest that 50 percent of women and 20 percent of men over 50 are at increased risk of fractures from osteoporosis. However, the diagnosis and treatment of osteoporosis are on a downward trend. If no changes are made by 2040, it is estimated that there will be an annual expense of $95 billion and over 3.2 million fractures per year in the United States alone. The National Osteoporosis Foundation (NOF), along with Healthy People 2030, recommends goals …