Medicine and Health Sciences Commons^™

Chacahoula 2022, Tram Phan

Chacahoula

Chacahoula 2022 includes the people and events that made the 2021-2022 school year at University of Louisiana at Monroe unique. Staff included

Tram Phan, Editor-in-Chief

Feature Writers:

Amir Alnajjar

Hanna Flynn

Alayna Pellegrin

Tram Phan

Evan Ranjitkar

Koshish Shrestha

Zoe Sissac

Tia Smith

Sports Writers:

Jonah Bostick

Cameron Jett

Designers:

Hanna Flynn

Tram Phan

Photographers:

Lanaya Bolden

Skylar Henry

Jeanette Robinson

Saugat Shrestha

Calli Sinclair

Paul Ware

1 Parents Experiences In Slovenia During The Covid-19 Pandemic, Petra Klanjsek, Leona Cilar Budler, Jadranka Stricevic, Tara L. Sacco, Barbara Kegl

Nursing Faculty/Staff Publications

Introduction: The COVID-19 pandemic emerged here in March 2020. The pandemic and lockdowns have been the cause of many parents doing both paid and unpaid work at home. Everyday life was a great challenge. Challenges, insecurities, and changes have caused people anxiety and fear, which has been and will only be reflected in the mental well-being of individuals. We wanted to find out how parents faced their fears, worries, and daily lives during the epidemic.

Methods: A cross-sectional study was conducted to gain insight into parents’ experiences during the COVID-19 pandemic in Slovenia. Casual parental sampling was used and a …

The Often‑Circuitous Path To Affirming Mental Health Care For Transgender And Gender‑Diverse Adults, Natalie Holt, Debra Hope, Richard Mocarski, Nathan Woodruff

Trans Collaborations Academic Papers

Purpose of Review We describe recent research regarding access to affirming mental health services for transgender and gender-diverse (TGD) adults and explore new resources available for therapists to inform evidence-based practice with TGD clients.

Recent Findings Barriers and facilitators at all socioecological levels impact TGD adults’ mental health help-seeking. TGD adults often interface with mental health providers while accessing gender-affirming medical care, though new standards of care are likely to alter this typically common path to mental health services. Efforts to improve therapist education, such as therapy manuals, are increasingly available and a necessary step to increase the number of …

Surgical Outcomes Following Posterior Spinal Fusion For Adolescent Idiopathic Scoliosis, Wyatt Benajmin David

Yale Medicine Thesis Digital Library

Surgical Outcomes Following Posterior Spinal Fusion for Adolescent Idiopathic ScoliosisWyatt B. David and Michael DiLuna. Section of Pediatric Neurosurgery, Department of Neurosurgery, Yale University, School of Medicine, New Haven, CT. Hospital size has previously been shown to impact outcomes in adult spine surgery. However, there is a paucity of studies assessing the impact of hospital size on outcomes in adolescent spine surgery. Furthermore, gender-based differences have been suggested in disease progression and outcomes of adolescent idiopathic scoliosis (AIS), though only a few studies have investigated these disparities. The aim of this study was to determine the impact of hospital size …

Whole Genome Sequencing For Identification Of Putative Causative Alleles For Hemochromatosis In Horses, Anna M. Rauber-Ramos

Schultz-Werth Award Papers

Hemochromatosis is liver disorder in which excess iron is stored in the liver, leading to iron overload and extensive liver damage that can prove fatal. Based on human precedence, a genetic cause for idiopathic hemochromatosis in horses is suspected. Two horses with hemochromatosis were whole genome sequenced, with variants in candidate genes prioritized in analyses of potential pathogenicity. No clear putative variants were found to be present in both horses, suggesting an etiology more complex than the initially suspected Mendelian inheritance. A heterozygous nonsense mutation in STEAP3 metalloreductase (STEAP3) was identified as a potential contributor to hemochromatosis in one of …

Pmh Connect, English (Greyscale For Printing), Sara W. Moyer, Patricia Kinser

School of Nursing Publications

Mental health related symptoms and associated experiences in the perinatal period present challenges, particularly regarding identification and appropriate management. Perinatal Mental Health (PMH) screening occurs in clinical settings on a more regular basis than ever before thanks to validated screening measures used at perinatal visits; however, pregnant and parenting individuals report several concerns when completing these screeners and providers report barriers in addressing resultant findings. To address barriers and enhance the PMH screening experience, this team of clinicians and researchers propose a tool – the PMH Connect: a Perinatal Mental Health Screening Connection, Education, and Decision Aid – to be …

Pmh Connect, EspañOl_Full Color, Sara W. Moyer, Patricia Kinser

School of Nursing Publications

Mental health related symptoms and associated experiences in the perinatal period present challenges, particularly regarding identification and appropriate management. Perinatal Mental Health (PMH) screening occurs in clinical settings on a more regular basis than ever before thanks to validated screening measures used at perinatal visits; however, pregnant and parenting individuals report several concerns when completing these screeners and providers report barriers in addressing resultant findings. To address barriers and enhance the PMH screening experience, this team of clinicians and researchers propose a tool – the PMH Connect: a Perinatal Mental Health Screening Connection, Education, and Decision Aid – to be …

Pmh Connect, EspañOl_Greyscale For Printing, Sara W. Moyer, Patricia Kinser

School of Nursing Publications

Mental health related symptoms and associated experiences in the perinatal period present challenges, particularly regarding identification and appropriate management. Perinatal Mental Health (PMH) screening occurs in clinical settings on a more regular basis than ever before thanks to validated screening measures used at perinatal visits; however, pregnant and parenting individuals report several concerns when completing these screeners and providers report barriers in addressing resultant findings. To address barriers and enhance the PMH screening experience, this team of clinicians and researchers propose a tool – the PMH Connect: a Perinatal Mental Health Screening Connection, Education, and Decision Aid – to be …

Pmh Connect, English, Full Color, Sara W. Moyer, Patricia Kinser

School of Nursing Publications

Mental health related symptoms and associated experiences in the perinatal period present challenges, particularly regarding identification and appropriate management. Perinatal Mental Health (PMH) screening occurs in clinical settings on a more regular basis than ever before thanks to validated screening measures used at perinatal visits; however, pregnant and parenting individuals report several concerns when completing these screeners and providers report barriers in addressing resultant findings. To address barriers and enhance the PMH screening experience, this team of clinicians and researchers propose a tool – the PMH Connect: a Perinatal Mental Health Screening Connection, Education, and Decision Aid – to be …

Rapid Onset Hydralazine-Induced Antineutrophil Cytoplasmic Antibody (Anca) Associated Vasculitis Presenting With Hemoptysis And Kidney Failure: Case Report, Rachel E. Easter, Andinet Gizaw, Natalie Klein

Internal Medicine Publications

Hydralazine-induced vasculitis can be challenging to recognize and diagnose as presenting symptoms vary and can mimic other conditions or diseases, however, swift intervention and treatment is key in halting progression of the disease and providing patients with the best possible outcomes. A 71-year-old African American female presented to the emergency department with weakness, fatigue, anemia, blood-streaked sputum, fever, chills, and severe myalgias. Hydralazine was prescribed to treat resistant hypertension eight months prior to presentation. Hydralazine was discontinued on hospital day (HD) 4. Pertinent laboratory values showed elevated inflammatory markers, positive antinuclear antibody (ANA), negative rheumatoid factor (RF), normal complement levels, …

The Future Of Clinical Trials Of Myopia Control, Mark A. Bullimore, Noel A. Brennan, Daniel I. Flintcroft

Articles

In the field of myopia control, effective optical or pharmaceutical therapies are now available to patients in many markets. This creates challenges for the conduct of placebo-controlled, randomised clinical trials, including ethics, recruitment, retention, selective loss of faster progressors and non-protocol treatments: 1. Ethics: It is valid to question whether withholding treatment in control subjects is ethical. 2. Recruitment: Availability of treatments is making recruitment into clinical trials more difficult. 3. Retention: If masking is not possible, parents may immediately withdraw their child if randomised to no treatment. 4. Selective loss: Withdrawal of fast progressors in the control group leading …

“Mind The Gap” - An Overview Of The Role Of The Extensions Community Healthcare Outcomes (Echo) Model In Enhancing Value In Health Care Delivery, Christina Kenny, Anushree Priyadarshini

Articles

The ECHO (Extensions Community Healthcare Outcomes) model of healthcare delivery has grown rapidly since its establishment and increased in popularity in recent years. This expansion has developed alongside the growing incidence of chronic diseases and the need to better manage them. The increasing uptake in ECHO has presented a requirement to assess its true value as healthcare costs are increasing globally, resulting in a growing demand by governments and policy makers to ensure chronic disease management strategies provide true value. Therefore, the aim of this review is to examine the impact that ECHO has on clinical practice and how such …

Serum 25-Hydroxyvitamin D Response To Vitamin D Supplementation Using Different Lipid Delivery Systems In Middle-Aged And Older Adults: A Randomised Controlled Trial, Aisling F. Mccourt, Steven L. Mulrooney, Graham O'Neill, E. Dolores O'Riordan, Aifric M. O'Sullivan

Articles

Food fortification improves vitamin D intakes but is not yet mandated in many countries. Combining vitamin D with different dietary lipids altered vitamin D absorption in in vitro and postprandial studies. This randomised, placebo-controlled trial examined the effect of the lipid composition of a vitamin D-fortified dairy drink on change in 25-hydroxyvitamin D (25(OH)D) concentrations. Sixty-three healthy adults aged 50+ years were randomised to one of the following for 4 weeks: vitamin D-fortified olive oil dairy drink, vitamin D-fortified coconut oil dairy drink, vitamin D supplement or placebo control dairy drink. All vitamin D groups received 20 µg of vitamin …

Three-Dimensional (3d) In Vitro Cell Culture Protocols To Enhance Glioblastoma Research, Janith Wanigasekara, Lara Carroll, Patrick J. Cullen, Brijesh K. Tiwari, James Curtin

Articles

Three-dimensional (3D) cell culture models can help bridge the gap between in vitro cell cultures and in vivo responses by more accurately simulating the natural in vivo environment, shape, tissue stiffness, stressors, gradients and cellular response while avoiding the costs and ethical concerns associated with animal models. The inclusion of the third dimension in 3D cell culture influences the spatial organization of cell surface receptors that interact with other cells and imposes physical restrictions on cells in compared to Two-dimensional (2D) cell cultures. Spheroids’ distinctive cyto-architecture mimics in vivo cellular structure, gene expression, metabolism, proliferation, oxygenation, nutrition absorption, waste excretion, …

Antibacterial And Antifungal Activity Of Methanolic Extracts Of Salix Alba L. Against Various Disease Causing Pathogens, Bilal Javed, F. Farooq, M. Ibrahim, H.A.B. Abbas, H. Jawwad, S.S. Zehra, H.M. Ahmad, A. Sarwar, K. Malik, K. Nawaz

Articles

The present study was aimed to manifest the antibacterial and antifungal activity of methanolic extracts of Salix alba L. against seven Gram-positive and Gram-negative bacterial pathogens e.g. Streptococcus pyogenes, Staphylococcus aureus (1), S. aureus (2), Shigella sonnei, Escherichia coli (1), E. coli (2) and Neisseria gonorrhoeae and three fungal isolates from the air such as Aspergillus terreus, A. ornatus, and Rhizopus stolonifer. Two different serotypes of S. aureus and E. coli were used. The agar well-diffusion method results showed the dose-dependent response of plant extracts against bacterial and fungal strains while some organisms were found resistant e.g. E. coli (1), …

Monitoring And Modelling The Glutamine Metabolic Pathway: A Review And Future Perspectives, Zohreh Mirveis, Paul Cahill, Nitin Patel, Hugh Byrne

Articles

In this review, the contribution of NMR to the metabolomics field will be discussed—particularly as it relates to cancer and drug metabolism research. An overview of the typical NMR metabolomic experiment will be presented while emphasizing important caveats ranging from experimental design to data interpretation.

Enhanced Gene Transfection Efficacy And Safety Through Granular Hydrogel Mediated Gene Delivery Process, Jing Zhang, Zhonglei He, Yinghao Li, Yu Shen, Guanfu Wu, Laura Power, Rijian Song, Ming Zeng, Xianqing Wang, Irene Lara Sáez, Sigen A, Qian Xu, James Curtin, Ziyi Yu, Wenxin Wang

Articles

Although gene therapy has made great achievements in both laboratory research and clinical translation, there are still challenges such as limited control of drug pharmacokinetics, acute toxicity, poor tissue retention, insufficient efficacy, and inconsistent clinical translation. Herein, a gene therapy gel is formulated by directly redispersing polyplex nanoparticles into granular hydrogels without any gelation pre-treatment, which provides great convenience for storage, dosing and administration. In vitro studies have shown that use of granular hydrogels can regulate the gene drug release, reduce dose dependent toxicity and help improve transfection efficacy. Moreover, the developed gene therapy gel is easy to operate and …

Machine-Learning-Based Head Impact Subtyping Based On The Spectral Densities Of The Measurable Head Kinematics, Xianghao Zhan, Yiheng Li, Yuzhe Liu, Nicholas J. Cecchi, Samuel J. Raymond, Zhou Zhou, Hossein Vahid Alizadeh, Jesse Ruan, Saeed Barbat, Stephen Tiernan, Olivier Gevaert, Michael M. Zeineh, Gerald A. Grant, David B. Camarillo

Articles

Traumatic brain injury can be caused by head impacts, but many brain injury risk estimation models are not equally accurate across the variety of impacts that patients may undergo and the characteristics of different types of impacts are not well studied. We investigated the spectral characteristics of different head impact types with kinematics classification. Methods: Data was analyzed from 3,262 head impacts from lab reconstruction, American football, mixed martial arts, and publicly available car crash data. A random forest classifier with spectral densities of linear acceleration and angular velocity was built to classify head impact types (e.g., football, car crash, …

Tio2-Mwcnt Nanohybrid: Cytotoxicity, Protein Corona Formation And Cellular Internalisation In Rtg-2 Fish Cell Line, Gabriela Helena Da Silva, Lidiane Silva Franqui, Marcelo A. De Farias, Vera Lucia S.S. De Castro, Hugh Byrne, Diego S.T. Martinez, Regina T.R. Monteiro, Alan Casey

Articles

Titanium dioxide nanoparticles-multiwalled carbon nanotubes (TiO2-MWCNT) nanohydrid has an enhanced photocatalytic activity across the visible light with promising applications in environmental remediation, solar energy devices and antimicrobial technologies. However, it is necessary to evaluate the toxicological effects of TiO2-MWCNT towards safe and sustainable development of nanohybrids. In this work, we studied the cytotoxicity, protein corona formation and cellular internalisation of TiO2-MWCNT on fibroblasts derived from gonadal rainbow trout tissue (RTG-2) for the first time. This nanohydrid did not show any toxicity effect on RTG-2 cells up to 100 mg L-1 after 24 h of exposure as monitored by alamar blue, …

Enhancing Clinical Judgment In Nursing Students, Mark Tanner

Health Sciences Education Symposium

Background/Objectives: Nurses need to be able to think critically and to use clinical judgment in order to competently do their work required of them in the clinical environment. The National Council of State Boards of Nursing (NCSBN) recognized this and developed the NCSBN Clinical Judgment Measurement Model (CJMM) in order to assess and measure clinical judgment on the NCLEX exams. This model was designed to give guidance to faculty so that they can help students develop the desired skills in critical thinking and clinical judgment. The faculty in a senior-level Adult Medical-Surgical Nursing used the CJMM to redesign the clinical …

Implementation Of A Required Professional Development Course Series In The Doctor Of Pharmacy Program, Nicole E. Omecene

Health Sciences Education Symposium

Purpose/Background: The assessment of professionalism is a challenging and evolving field. The pharmacy education literature describes approaches to assessing professionalism over time; however, an integrated professionalism course series spanning the duration of the program has not been described.1,2 Co-curricular experiences present an opportunity for students to apply content learned in the classroom to real-world experiences where professionalism is expected. These activities include leadership positions, career seminars and health outreach events. Previously described processes for tracking the co-curricular activities differ in the accuracy of data collected and the connection to a professional development course.3,4 The purpose of this educational project is …

An Interprofessional Active-Learning Laboratory On Urinary Incontinence, Krista L. Donohoe

Health Sciences Education Symposium

Background/Objectives:Urinary incontinence (UI) is a common syndrome with peak prevalence in older adulthood. Involuntary loss of urine from the bladder may be due to physical abnormalities, pelvic floor dysfunction, or reversible causes, like medication or infection.1 UI is an underreported and underdiagnosed geriatric syndrome that significantly impacts quality of life, increases risk of institutionalization, and contributes to significant patient- and system-level healthcare expenditures.1 Healthcare practitioners require knowledge and skills necessary to provide quality care to older adults with UI. The National Institute of Diabetes and Digestive and Kidney Diseases, National Institute on Aging, and American Geriatrics Society recommend the healthcare …

Interprofessional Development And Evaluation Of A Virtual Reality Haptic Surgical Training System For Retropubic Midurethral Slings, Lauren Siff

Health Sciences Education Symposium

Purpose and background: Procedures like the midurethral sling, performed without open visual or camera access rely on the surgeon’s spatial orientation of anatomical landmarks and haptic sensation. The “Blind” nature of this technique can results in serious complications^1–4. Surgeons are typically trained via an apprenticeship on live patients, static models, or, cadaver labs. These methods carry higher potential risks for patient safety, significant expense, often require travel, and are limited by distortion of anatomy after multiple uses. Adding haptics and AI to VR simulators has been shown to improve fidelity, realism, and educational value^ 5–10.We formed a transdisciplinary team to …

Virtual, Non-Clinical “Bootcamp” To Prepare For The Nbme Subject Matter (Shelf) Exam During The Pediatric Clerkship, Clifton Lee

Health Sciences Education Symposium

Background: Medical education changed due to the COVID-19 pandemic. Educational sessions were offered virtually. There are published education innovations for pre-clinical curricula (1). However, providing virtual education during the clinical clerkship was a daunting challenge. In addition to the delay in patient care exposure, students’ performance in the NBME Subject Matter (Shelf) Exam scores have declined during the pandemic (2). VCU School of Medicine also needed to provide continued instructions to students whose clinical clerkships were delayed.

Description of the Innovation: Due to the COVID-19 pandemic, the clinical start for the class of 2022 was delayed by 3 months. During …

The Value Of Positive Feedback: An Underutilized Tool In Ophthalmology Resident Education, Meagan Shinbashi

Health Sciences Education Symposium

Purpose/Background/Objectives: Little research has been performed on the use of positive feedback as a teaching tool in ophthalmology postgraduate medical education settings. Additionally, there is a paucity of research assessing the effectiveness of feedback from trainees’ perspectives. To address these gaps, we explored the effects of positive feedback on resident professional identity formation, performance, and wellness through a pilot program within the ophthalmology residency program’s wellness curriculum at Virginia Commonwealth University.

Methods: This study employed quantitative data collection through surveys before and after a positive feedback exercise activity of ophthalmology residents at the Virginia Commonwealth University Health System. Participants were …

Research4life (R4l) Scholar Program: New Initiative To Promote Diversity, Equity, And Inclusion In Medicine Through A Bottom-Up Approach, Somaya Albhaisi

Health Sciences Education Symposium

Purpose and background: According to the Pew Research Center, Hispanics are 17% of the workforce but only represent 8% of people in a science, technology, engineering and math (STEM) position. African Americans are 11% of the workforce but hold 9% of STEM jobs. The Research4Life (R4L) program is designed to increase the number of minority students who pursue medical education and careers in Medicine and research. A formalized mentorship and clinical research program is one pipeline to increase representation of underrepresented groups in medicine and academic medical careers.(1)

Description of Innovative Practice: The R4L scholar program is a structured summer …

The Neoresident Curriculum: A Combined Learning Experience For Pediatric Residents, Kelly Stanley

Health Sciences Education Symposium

Purpose and background, including relevant citations: All pediatric residents are required to rotate through the neonatal intensive care unit (NICU). The NICU is a unique unit that provides care for premature and ill neonates. At Children’s Hospital of Richmond at VCU (CHOR VCU), pediatric residents complete 12 weeks in the NICU, 4 weeks each year. As a part of this rotation, these residents are responsible for attending high risk deliveries. At birth about 10% of neonates will require resuscitation (1). Before starting residency, each resident is required to complete the neonatal resuscitation program (NRP). This certification requires renewal every two …

Pilot Test Of A Large-Scale, First-Hand Research Opportunity For Medical Students, Brian Cassel

Health Sciences Education Symposium

Purpose and background: While VCU is an R1 university, many students graduate without first-hand research experience. We sought to create a new learning opportunity for second year medical students (M2s) through access to real-world clinical data from a federated research network of healthcare organizations, TriNetX. TriNetX gives users access to millions of de-identified patient records for a wide variety of purposes: cohort discovery; determining possible enrollment rates for clinical trials; evaluating outcomes; and evaluating disparities. Several VCU researchers have published studies using TriNetX data [i]. Prior to our project, TriNetX access and instruction had not been pushed out to medical …

Standardized Patient Simulations: A Pilot Program In The Ophthalmology Residency Curriculum, Yusrah Hasan

Health Sciences Education Symposium

Background: Patient simulations are being used to provide a safe environment for learners to practice giving bad news to patients.

Methods: This series of simulations was implemented at Virginia Commonwealth University Ophthalmology Residency program among three cohorts of residents in 2019, 2020 and 2021. Each simulation involves a case scenario in which the learner must synthesize clinical information to recognize a patient’s diagnoses and deliver bad news to the patient in a tactful manner.

Results: Post-simulation surveys were completed by the 2020 and 2021 cohort of residents. All learners felt that the experience improved their communication skills with patients. 44% …

Strength In Caring: An Interprofessional Innovation To Cultivate Organizational Wellness, Kelly Lockeman

Health Sciences Education Symposium

Background. The impact of COVID-19 on the physical and mental health of individual providers and entire health care systems has had a devastating blow to already fragile networks.[1] It is imperative to identify strategies that heal, repair, and build capacity in health care providers and fix the system in which they practice. Building resilience through self-care is only a part of the solution.[2,3] Health care organizations are striving for solutions that target issues such as psychological safety, interprofessional teamwork, and wellness-centered leadership, which are more likely to reduce burnout than individualized self-care programs.[4,5] The purpose of the Strength in Caring …