Medicine and Health Sciences Commons^™

Hospital Adhering To The Ten Steps To Successful Breastfeeding Predicts Exclusive Breastfeeding In Latinx Mothers., Ana Linares, Diana Cartagena, Marialda Moreira Christoffel

Nursing Faculty Publications

Introduction: Assessing how well a hospital adheres to the Ten Steps to Successful Breastfeeding is the key to outlining necessary modifications in mother breastfeeding support. This study aimed to assess Latinx mothers’ perception of how well a hospital adheres to the Ten Steps to Successful Breastfeeding and its influence on exclusive breastfeeding (EBF) rates at hospital discharge.

Methods: Secondary analysis of two longitudinal studies. The combined sample (N = 74) of Latinx pregnant women residing in the US. We modified, translated, and evaluated reliability of the Questionnaire for the Breastfeeding Mother (QBFM), which was applied to evaluate mothers’ …

Design Guidelines For Homeless Shelter And Resource Center Site Plans, Samuel Johnson

All Graduate Reports and Creative Projects, Fall 2023 to Present

Homelessness is one of the most pressing humanitarian issues facing the country today. Lack of affordable housing, among many other complicating factors, have led to many cities scrambling to find both short-, middle-, and long-term solutions to the issue. The Covid-19 pandemic added a disruption in services, critical record-keeping, and data-gathering, which has further confounded experts looking for an effective path forward. As it stands, there is a significant gap in academic research addressing best practices for shelter site design, particularly as it relates to landscape. The role of landscape and greenspace within and around a shelter is not well …

Designing And Validating Novel Communication Measures For Pediatric, Adolescent, And Young Adult Oncology Care And Research: The Pedcom Measures, Bryan A. Sisk, Amy R. Newman, Dandan Chen, Jennifer W. Mack, Bryce B. Reeve

College of Nursing Faculty Research and Publications

Background

High-quality communication in pediatric and adolescent cancer is the standard of care. Yet, we lack pediatric-specific communication measures. We designed self-report and caregiver-report communication measures for use in pediatric oncology settings.

Methods

We recruited adolescent and young adults (AYAs; 12–24 years) with cancer and parents of children and AYAs between 1 month post-diagnosis and 2 months after completing treatment. Participants completed measures including 58 questions addressing eight previously characterized communication functions. For each function, we conducted factor analysis, and assessed reliability and construct validity. Based on psychometric properties, we created final long-form (31 items) and short-form (eight items) communication …

Increasing And Monitoring Medication Adherence By Implementing A Long-Acting Injection Screening Tool, Analee Ryals

Doctoral Projects

Medication nonadherence leads to a high risk of deterioration in patients diagnosed with a mental illness. Medication nonadherence is more likely in patients who are taking daily oral medications when compared to patients on long-acting injectable antipsychotics (LAIs) (Chakrabarti, 2014). Millions of people are diagnosed with bipolar disorder or schizophrenia and treated with various medications. However, LAIs are under-utilized as a long-term treatment option for patients diagnosed with a mental illness. Patients who are prescribed LAI have a better quality of life and are more closely monitored by their healthcare providers (Kaplan et al., 2013). The implementation of an LAI …

Over 200 Dalarna University Alumni Help Advance Education And Care In Africa And Asia: A Short Communication, Kerstin Erlandsson, Marie Klingberg Allvin

Journal of Asian Midwives (JAM)

No abstract provided.

Exploring Midwives' Challenges And Strategies To Provide Care In Maternity Settings During Harsh Winter Weather In Northern Areas, Pakistan: A Qualitative Study Protocol, Sana Sultan, Rafat Jan, Marina Baig

Journal of Asian Midwives (JAM)

Background: Midwives play a vital role in enhancing the quality of care and achieving substantial reductions in maternal and newborn mortality rates. However, in the context of Gilgit Baltistan, the harsh winter weather, and frequent heavy snowfall present distinct challenges for midwives providing essential maternal care. These challenges can lead to an increased risk of maternal infections and newborn hypothermia. Consequently, the limited accessibility to healthcare facilities due to frequent harsh winter weather, and resulting scarcity of resources like heating, electricity, and water further exacerbates the situation.
Objective: The objective of the study is to explore the challenges and barriers …

Nurse-Led Newborn Parent Education Program – A Qualitative Study To Explore Nurses' Experiences As Newborn Parent Educators, Shelina Bhamani, Zaibunissa Karim, Ceemal Khan, Amina Lakhani, Khairunnissa Hooda, Lumaan Sheikh

Journal of Asian Midwives (JAM)

Background: Parents require support while caring for their newborns. Nurses can be supportive in helping parents learn how to care for their newborns and their well-being and supporting their spouses and families based on the cultural and social norms of the local context of Pakistan. Newborn parent education programs play a crucial role in advancing the knowledge and skills of the nurses required for parent education. This research study aims to explore nurses' experiences as newborn parent educators after enrolling and implementing a pilot project of a newborn parent education program at a tertiary care university hospital.
Methods: The exploratory …

Swaddling A Newborn Promotes Sleep And Keeps The Baby Calm: A Truth Or A Myth?, Ateefa Al-Noor, Anshara Merchant

Journal of Asian Midwives (JAM)

Swaddling is a traditional way of wrapping the baby in a cloth that helps them to remain calm and eliminate anxiety. It promotes sleep but at the same time can also be associated with certain risks such as Sudden Infant Death Syndrome (SIDS). Swaddling can be beneficial but measures are required to minimize known risks. Swaddling can be favorable in the initial few weeks but it should be discontinued once the baby starts to roll from its back. The aim of this paper is to educate families regarding the proper technique of swaddling; its pros and cons. Further research is …

Hip Healthy Swaddling: A Commentary, Mehreen Aslam

Journal of Asian Midwives (JAM)

Swaddling, the practice of covering babies to align the legs, prevent hip movement, carries a risk of Developmental Dysplasia of the Hip (DDH).Correct swaddling techniques, emphasizing hip flexibility, mitigate risks and are promoted globally. Cultural shifts, as seen in Turkey and Japan, reflect awareness of swaddling's impact on hip health. In certain cultures, 90% of mothers swaddle infants for comfort, predominantly to keep legs straight, but traditional swaddling contributes to hip dysplasia risk, contrasting with the recommended technique allowing free limb movement. Proper education on swaddling is crucial, aligning with health benefits and reducing DDH occurrences. Recommendations include routine hip …

Because Breastfeeding Is Never Done Alone, Mehtab Lalwani, Kiran Nawaz Ali

Journal of Asian Midwives (JAM)

No abstract provided.

Out-Of-Hospital Births: A Small But Growing Phenomenon In High Income Countries: A Viewpoint, Céline Miani, Stephanie Batram-Zantvoort, Emma Pitchforth, Bethan Treadgold, Krista Johnston, Virginie Rozée, Christiana Macdougall, Clemence Schantz, Edwin Van Teijlingen

Journal of Asian Midwives (JAM)

No abstract provided.

Utilization And Determinants Of Antenatal Care Services, Worlanso Awungshi Shimray, Adahrii Ashuni, Anamika Toppo, Lal Khawngaihi, Lalram Beiseii, Medo- Vinü, Vikethono Luho

Journal of Asian Midwives (JAM)

Background: Antenatal care (ANC) offers an opportunity for early detection and prevention of pregnancy-related risk and complications, as well as for delivering effective therapy of both current and potential issues. Numerous studies have indicated that inadequate use of the available ANC services contributes to maternal and child morbidity and mortality. The purpose of the current study is to evaluate the utilization and assess the determinants of antenatal care services in Singrijan, Nagaland, India.
Method: A cross-sectional exploratory community-based study was conducted in Singrijan. Purposive sampling was used to recruit a total of 72 mothers with a history of at least …

Factors Associated With Genito-Pelvic Pain/Penetration Disorder In Women: A Review Article, Kiran Karim Jivani, Tazeen S. Ali, Arusa Lakhani, Fauzia Basaria Hasnani

Journal of Asian Midwives (JAM)

Globally, the sexual responses of genito-pelvic pain/penetration disorder-affected women is poorly understood. This deficit is due, in part, to these women being prone to incorrect pathologic rankings in intercourse-related questionnaires, thereby lowering the dependability of results. Although patients with genito-pelvic pain/penetration disorder display sexual intent, they typically avoid sexual circumstances in which penetration is involved. Gynaecological examinations are also frequently avoided, despite medical advice. The factors linked to genito-pelvic pain/penetration disorder identified in this review are; age, educational status, financial status, different relationship patterns, negative cognition, decreased sexual desire, no use of artificial lubricants, insufficient sexual arousal, history of sexual …

Deficiency Of Acute-Phase Serum Amyloid A Exacerbates Sepsis-Induced Mortality And Lung Injury In Mice, Ailing Ji, Andrea C. Trumbauer, Victoria P. Noffsinger, Luke W. Meredith, Brittany Dong, Qian Wang, Ling Guo, Xiangan Li, Frederick C. De Beer, Nancy R. Webb, Lisa R. Tannock, Marlene E. Starr, Christopher M. Waters, Preetha Shridas

Saha Cardiovascular Research Center Faculty Publications

Serum amyloid A (SAA) is a family of proteins, the plasma levels of which may increase >1000-fold in acute inflammatory states. We investigated the role of SAA in sepsis using mice deficient in all three acute-phase SAA isoforms (SAA-TKO). SAA deficiency significantly increased mortality rates in the three experimental sepsis mouse models: cecal ligation and puncture (CLP), cecal slurry (CS) injection, and lipopolysaccharide (LPS) treatments. SAA-TKO mice had exacerbated lung pathology compared to wild-type (WT) mice after CLP. A bulk RNA sequencing performed on lung tissues excised 24 h after CLP indicated significant enrichment in the expression of genes associated …

Ecohiv-Infected Mice Show No Signs Of Platelet Activation, Hammodah Rawhi Hammodah Alfar, Dominic Ngima Nthenge-Ngumbau, Kathryn E. Saatman, Sidney W. Whiteheart

Saha Cardiovascular Research Center Faculty Publications

Platelets express several surface receptors that could interact with different viruses. To understand the mechanisms of HIV-1′s interaction with platelets, we chose the EcoHIV model. While EcoHIV is an established model for neuroAIDS, its effects on platelets are ill-defined. Our results indicate that EcoHIV behaves differently from HIV-1 and is cleared from circulation after 48 h post- infection. The EcoHIV course of infection resembles an HIV-1 infection under the effects of combined antiretroviral therapy (cART) since infected mice stayed immunocompetent and the virus was readily detected in the spleen. EcoHIV-infected mice failed to become thrombocytopenic and showed no signs of …

Loss Of Carnitine Palmitoyltransferase 1a Reduces Docosahexaenoic Acid-Containing Phospholipids And Drives Sexually Dimorphic Liver Disease In Mice, Mikala M. Zelows, Corissa Cady, Nikitha Dharanipragada, Anna E. Mead, Zachary A. Kipp, Evelyn A. Bates, Venkateshwari Varadharajan, Rakhee Banerjee, Se-Hyung Park, Nathan R. Shelman, Harrison A. Clarke, Tara R. Hawkinson, Terrymar Medina, Ramon C. Sun, Todd A. Lydic, Terry D. Hinds, Jr., J. Mark Brown, Samir Softic, Gregory A. Graf, Robert N. Helsley

Saha Cardiovascular Research Center Faculty Publications

Background and aims: Genome and epigenome wide association studies identified variants in carnitine palmitoyltransferase 1a (CPT1a) that associate with lipid traits. The goal of this study was to determine the role of liver-specific CPT1a on hepatic lipid metabolism.

Approach and results: Male and female liver-specific knockout (LKO) and littermate controls were placed on a low-fat or high-fat diet (60% kcal fat) for 15 weeks. Mice were necropsied after a 16 h fast, and tissues were collected for lipidomics, matrix-assisted laser desorption ionization mass spectrometry imaging, kinome analysis, RNA-sequencing, and protein expression by immunoblotting. Female LKO mice had increased serum alanine …

Dentistry And The Law: Requiring Proof Of Adoption/Retaining Orthodontic Models, Dan Schulte Jd

The Journal of the Michigan Dental Association

In this Dentistry and the Law column, a dentist seeks guidance on handling a situation where racial differences between a child and an accompanying adult raised concerns during an examination, leading the dentist to request proof of adoption. The response clarifies that asking for proof of adoption is not illegal, citing relevant Michigan adoption statutes. The column advises adopting an office policy, emphasizing human trafficking training. Additionally, a dentist inquires about retaining orthodontic models and X-ray films. The answer recommends assuming orthodontic models are part of dental records, subject to a 10-year retention period. Patients can be given their models, …

Endodontic Therapy, Crown Amputation, And Soft Tissue Advancement To Treat A Hopeless Tooth, Timothy Daws Dds, Thomas Bolten Dds, Md

The Journal of the Michigan Dental Association

Managing patients with a history of intravenous bisphosphonates and antiresorptive medications poses challenges in clinical decision-making. Extractions are generally discouraged in these patients due to the risk of medication-related osteonecrosis of the jaw (MRONJ). This case study presents an 89-year-old female with metastatic breast cancer on Xgeva, facing a non-restorable tooth (#30). A collaborative approach involving the general dentist, endodontist, and oral surgeon employed endodontic therapy, crown amputation, and soft tissue advancement, avoiding extraction. The technique, akin to coronectomy, mitigates MRONJ risk by preserving bone integrity. Follow-up assessments indicate successful treatment without complications, highlighting the efficacy of this approach in …

Investigating The Relationship Between Consistent Workout Regimen On Quality Of Life Among Crossfitters In South Mississippi, Christian Glass

Honors Theses

Robust literature exists to support the utility of CrossFit in improving metabolic and cardiovascular well-being. However, a metaphorical chasm exists not in the study of the physiological effects of CrossFit but in the psychological effects, namely quality of life (QOL). This thesis aimed to offer an installment into this gap by investigating trends among a population of 81 CrossFitters in south Mississippi. To best fulfill this task, a quantitative study was conducted using a 32-item survey composed of a mixture of questions from the World Health Organization Quality of Life Brief Version (WHOQOL- BREF) to assess reported quality of life …

Nurses’ Perceptions Of Ppe Compliance Among South Mississippi Medical- Surgical Nurses, Jenna Roush

Honors Theses

Utilizing Personal Protective Equipment (PPE) appropriately is critical in protecting nurses and patients from contracting infectious diseases. Poor compliance with PPE is associated with increased hospital-acquired infections and directly impacts infection control measures. This thesis delves into the perceptions of PPE compliance and awareness among medical-surgical nurses in South Mississippi. A quantitative study utilizing a 28-item survey was implemented. Likert-style and open-ended survey questions were completed by n=28 participants. Univariate analysis was used to determine compliance among each PPE item, awareness and confidence of PPE items, and whether there was a lack of training or a PPE shortage. Based on …

Non-Operative Management Strategy For Blunt Pulmonary Artery Pseudoaneurysm: A Case Report, Declan A. Feery, Kevin Kuruvilla, Allison G. Mcnickle, Douglas R. Fraser

Department of Surgery Faculty Research

Traumatic pulmonary artery pseudoaneurysms (PAP) are rare findings and are often associated with penetrating trauma to the chest. We present a case of a pulmonary artery pseudoaneurysm following blunt trauma. A 49-year-old man presented after a motor vehicle collision. Contrast enhanced computed tomography scans of the neck, chest, abdomen, and pelvis were obtained demonstrating a proximal right pulmonary artery pseudoaneurysm, small volume hemopericardium, left first rib fracture, and focal non-flow limiting dissection of left subclavian artery. For the management of right PAP, we adopted a non-operative management strategy with an esmolol infusion for strict heart rate and blood pressure control. …

From The Borders Edge To The Brink Of Death: A Case Of A Traumatic Pancreatic Injury And Whipple Procedure In The Rio Grande Valley, Valentine S. Alia, Ed W. Alvarado, Edward M. Diaz, Daniel Albo, Roger Galindo

School of Medicine Publications

The traumatic pancreatoduodenectomy, also known as the traumatic Whipple, is a specialized surgical procedure often reserved for extreme cases in which an individual suffers traumatic injuries to the pancreas, duodenum, or periampullary structures. Traditionally, a Whipple procedure is a complex surgery involving the removal of the head of the pancreas, duodenum, and a portion of both the bile duct and stomach, for the management of pancreatic head cancer. In underserved communities where limited access to healthcare is coupled with a higher incidence of trauma, the lack of specialized and supportive care for patients suffering from pancreatic injuries may lead to …

The Psychological Science Accelerator's Covid-19 Rapid-Response Dataset, Erin M. Buchanan, Andree Hartanto

Research Collection School of Social Sciences

In response to the COVID-19 pandemic, the Psychological Science Accelerator coordinated three large-scale psychological studies to examine the effects of loss-gain framing, cognitive reappraisals, and autonomy framing manipulations on behavioral intentions and affective measures. The data collected (April to October 2020) included specific measures for each experimental study, a general questionnaire examining health prevention behaviors and COVID-19 experience, geographical and cultural context characterization, and demographic information for each participant. Each participant started the study with the same general questions and then was randomized to complete either one longer experiment or two shorter experiments. Data were provided by 73,223 participants with …

An Investigation Of Match For Lossless Video Compression, Brittany Sullivan-Reicks

Department of Electrical and Computer Engineering: Dissertations, Theses, and Student Research

A new lossless video compression technique, Match, is investigated. Match uses the similarity between the frames of a video or the slices of medical images to find a prediction for the current pixel. A portion of the previous frame is searched to find a matching context, which is the pixels surrounding the current pixel, within some distance centered on the current location. The best distance to use for each dataset is found experimentally. The matching context refers to the neighborhood of w, nw, n, and ne, where the pixel in the previous frame with the closest matching context becomes the …

System Dynamics Modeling For Cancer Prevention And Control: A Systematic Review, Erin S. Kenzie, Mellodie Seater, Wayne Wakeland, Gloria Coronado, Melinda M. Davis

Complex Systems Faculty Publications and Presentations

Cancer prevention and control requires consideration of complex interactions between multilevel factors. System dynamics modeling, which consists of diagramming and simulation approaches for understanding and managing such complexity, is being increasingly applied to cancer prevention and control, but the breadth, characteristics, and quality of these studies is not known. We searched PubMed, Scopus, APA PsycInfo, and eight peer-reviewed journals to identify cancer-related studies that used system dynamics modeling. A dual review process was used to determine eligibility. Included studies were assessed using quality criteria adapted from prior literature and mapped onto the cancer control continuum. Characteristics of studies and models …

Heading Towards Relief: An Evaluation Of Headache Management In A Community Hospital., Caleb Hoppe Pharmd, Sarah Meeks Pharmd, Bcccp, Heather Nichols Pharmd, Bcpps, Sarah Ferrell Pharmd, Bcpps

Pharmacy Residency

Presented at the ASHP Midyear Clinical Meeting. December 2023.

This study sought to examine the treatment of acute headache at a community hospital including prescribing habits, dosing practices, use of consultants, and analgesic effect of each medication.

A Review Of Guideline Directed Medication Therapy Adherence For Patients With Asthma., Jennifer Mccarthy Pharmd, Ms, Elizabeth Meisberger Pharmd, Bcps, Bccp, Sarah Pfaehler Pharmd, Mba, Bcps, Pacs, Bhavika Patel Pharmd

Pharmacy Residency

Presented at the ASHP Midyear Clinical Meeting. December 2023.

This project evaluated a health system’s prescribing adherence to the 2022 GINA guideline update for inhaled corticosteroid (ICS) in combination with a long-acting beta agonist (LABA) as preferred reliever/rescue therapy for asthma within the ambulatory setting.

Community Acquired Pneumonia Order Set Utilization Evaluation: A Retrospective Chart Review, Kristin Lytal Pharmd, Mspgx, Luke Keller Pharmd, Bcps, Bcccp, Blake Burton Pharmd, Bcps, Sarah Ferrell Pharmd, Bcpps

Pharmacy Residency

Presented at the ASHP Midyear Clinical Meeting. December 2023.

This poster evaluated adherence of antimicrobial regimen selection using a community acquired pneumonia (CAP) order set updated to Infectious Disease Society of America/American Thoracic Society guidelines.

Genome-Wide Significant Risk Loci For Mood Disorders In The Old Order Amish Founder Population, Elizabeth M. Humphries, Kwangmi Ahn, Rachel L. Kember, Fabiana L. Lopes, Evelina Mocci, Juan M. Peralta, John Blangero, David C. Glahn, Fernando S. Goes, Peter P. Zandi

School of Medicine Publications

Genome-wide association studies (GWAS) of mood disorders in large case-control cohorts have identified numerous risk loci, yet pathophysiological mechanisms remain elusive, primarily due to the very small effects of common variants. We sought to discover risk variants with larger effects by conducting a genome-wide association study of mood disorders in a founder population, the Old Order Amish (OOA, n = 1,672). Our analysis revealed four genome-wide significant risk loci, all of which were associated with >2-fold relative risk. Quantitative behavioral and neurocognitive assessments (n = 314) revealed effects of risk variants on sub-clinical depressive symptoms and information processing speed. …

Muc13 Drives Cancer Aggressiveness And Metastasis Through The Yap1-Dependent Pathway, Kyle Doxtater, Manish Tripathi, Radhiki Sekhri, Bilal B. Hafeez, Sheema Khan, Nadeem Zafar, Stephen Behrman, Murali M. Yallapu, Meena Jaggi, Subhash C. Chauhan

School of Medicine Publications

Anchorage-independent survival after intravasation of cancer cells from the primary tumor site represents a critical step in metastasis. Here, we reveal new insights into how MUC13-mediated anoikis resistance, coupled with survival of colorectal tumor cells, leads to distant metastasis. We found that MUC13 targets a potent transcriptional coactivator, YAP1, and drives its nuclear translocation via forming a novel survival complex, which in turn augments the levels of pro-survival and metastasis-associated genes. High expression of MUC13 is correlated well with extensive macrometastasis of colon cancer cells with elevated nuclear YAP1 in physiologically relevant whole animal model systems. Interestingly, a positive correlation …