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Articles 1171 - 1200 of 27433
Full-Text Articles in Medicine and Health Sciences
Moral Distress In Critical Care Nursing: A Literature Review, Anna Tindell
Moral Distress In Critical Care Nursing: A Literature Review, Anna Tindell
The Eleanor Mann School of Nursing Undergraduate Honors Theses
Moral distress is a pressing concern in the healthcare field with significant implications for all areas of nursing and patient outcomes. However, those within the specialty of critical care nursing experience moral distress more frequently than those in other specialties. It arises from the complex ethical dilemmas nurses in critical intensive care units face as they work in these high-pressure environments. The purpose of this literature review is to discuss moral distress in critical care nursing and how it affects a nurse’s ability to provide quality care. Furthermore, this review will determine factors contributing to moral distress and potential interventions …
Breastfeeding In Public: A Review Of Literature And Service Learning Experience, Taylor Jehlik, Makenzie Carney
Breastfeeding In Public: A Review Of Literature And Service Learning Experience, Taylor Jehlik, Makenzie Carney
The Eleanor Mann School of Nursing Undergraduate Honors Theses
This article explores the perceptions and beliefs of first-time expectant mothers, their family members, and their social network about breastfeeding in public places. We used experience through Tiny Tusks and reviewed literature to get a better understanding of what social factors play a role in mothers' decisions to breastfeed in public.
Evaluation Of Caring Behaviors In High-Fidelity Simulation Following A Caring Concept Educational Intervention, Debra Ann Mcwilliams
Evaluation Of Caring Behaviors In High-Fidelity Simulation Following A Caring Concept Educational Intervention, Debra Ann Mcwilliams
Theses & Dissertations
Background.
Simulation has created a new paradigm in nursing education. Behaviors that demonstrate caring are important aspects of quality nursing practice. Nursing education needs to integrate opportunities to teach caring, and simulation is an ideal environment to do this. Faculty must assist nursing students to establish competence in psychomotor, cognitive, and the affective domains of learning. Many of the widely used, standardized scenarios in simulation predominantly focus on critical-thinking skills while marginalizing the demonstration of caring behaviors.
Purpose.
The purpose of this quantitative study was to examine the effect of a caring concept educational intervention (CCEI) in students’ self-reported confidence …
Factors Influencing The Delivery Of Preconception Care Services Among Nursing And Midwifery Students At Aga Khan University, Kenya, Levy Mukolwe
MSc in Advanced Practice Midwifery
Preconception care (PCC) encompasses a range of biomedical, behavioural, and social interventions to improve pregnancy outcomes. However, the effective implementation of PCC services, particularly in developing countries, faces multifaceted challenges. This cross-sectional quantitative descriptive study was conducted among 104 nursing and midwifery students at Aga Khan University and selected through simple random sampling. Data was collected using semi-structured self-administered questionnaires and analyzed using SPSS version 25.0. 69.9% of the respondents were nurses, while 30.1% were midwives. 28.8% of participants knew the definition of PCC. The importance of various PCC components, such as nutritional deficiency screening, genetic risk assessment, environmental hazard …
Postoperative Stomach Volvulus And Pancreatitis Following A Sleeve Gastrectomy., Shane B Devine, Sam J King, Bradley J Chatterton, Kurt D Knepley
Postoperative Stomach Volvulus And Pancreatitis Following A Sleeve Gastrectomy., Shane B Devine, Sam J King, Bradley J Chatterton, Kurt D Knepley
Internal Medicine Resident Research
The laparoscopic sleeve gastrectomy is the most common bariatric surgery performed to promote weight loss and improve obesity-related comorbidities. As the number of patients undergoing sleeve gastrectomy increases, so does the prevalence of complications. It is crucial to recognize both common and unusual complications of sleeve gastrectomy to properly diagnose and manage them. We present a unique case of gastric outlet obstruction not visualized on initial imaging and acute pancreatitis following a sleeve gastrectomy. We recommend performing an endoscopy and ordering serum lipase levels in a patient with negative CT scans but persistent postoperative nausea, vomiting, and abdominal pain. The …
The Use Of Deception In Dementia-Care Robots: Should Robots Tell "White Lies" To Limit Emotional Distress?, Samuel R. Cox, Grace Cheong, Wei Tsang Ooi
The Use Of Deception In Dementia-Care Robots: Should Robots Tell "White Lies" To Limit Emotional Distress?, Samuel R. Cox, Grace Cheong, Wei Tsang Ooi
ROSA Journal Articles and Publications
With projections of ageing populations and increasing rates of dementia, there is need for professional caregivers. Assistive robots have been proposed as a solution to this, as they can assist people both physically and socially. However, caregivers often need to use acts of deception (such as misdirection or white lies) in order to ensure necessary care is provided while limiting negative impacts on the cared-for such as emotional distress or loss of dignity. We discuss such use of deception, and contextualise their use within robotics.
Relationship Between Arm Path, Ball Velocity, And Elbow Varus Torque In Professional Baseball Pitchers, Brittany Dowling, Alexander Hodakowski, Bjorn Olmanson, Matthew Cohn, Patrick Pauley, Nikhil Verma, Gregory Nicholson, Grant Garrigues
Relationship Between Arm Path, Ball Velocity, And Elbow Varus Torque In Professional Baseball Pitchers, Brittany Dowling, Alexander Hodakowski, Bjorn Olmanson, Matthew Cohn, Patrick Pauley, Nikhil Verma, Gregory Nicholson, Grant Garrigues
Rothman Institute Papers
BACKGROUND: Currently, most pitching instructors suggest a shorter arm path-the total distance the arm travels during pitching. Theoretically, this combination allows for better body segment sequencing, a more efficient energy transfer through the kinetic chain, and increased ball velocity, while limiting elbow varus torque.
HYPOTHESIS: Shorter arm paths would be associated with increased ball velocity and decreased elbow varus torque.
STUDY DESIGN: Descriptive laboratory study.
METHODS: A total of 182 professional pitchers threw 8 to 12 fastball pitches while evaluated by 3-dimensional motion capture (480 Hz). The arm path was calculated as the total distance the hand marker traveled during …
A Gold-Based Inhibitor Of Oxidative Phosphorylation Is Effective Against Triple Negative Breast Cancer, R. Tyler Mertens, Jong Hyun Kim, Samuel Ofori, Chibuzor Ngozi Olelewe, Paul J. Kamitsuka, Gunnar F. Kwakye, Samuel G. Awuah
A Gold-Based Inhibitor Of Oxidative Phosphorylation Is Effective Against Triple Negative Breast Cancer, R. Tyler Mertens, Jong Hyun Kim, Samuel Ofori, Chibuzor Ngozi Olelewe, Paul J. Kamitsuka, Gunnar F. Kwakye, Samuel G. Awuah
Markey Cancer Center Faculty Publications
Triple-negative breast cancer (TNBC) is associated with metabolic heterogeneity and poor prognosis with limited treatment options. New treatment paradigms for TNBC remains an unmet need. Thus, therapeutics that target metabolism are particularly attractive approaches. We previously designed organometallic Au(III) compounds capable of modulating mitochondrial respiration by ligand tuning with high anticancer potency in vitro and in vivo. Here, we show that an efficacious Au(III) dithiocarbamate (AuDTC) compound induce mitochondrial dysfunction and oxidative damage in cancer cells. Efficacy of AuDTC in TNBC mouse models harboring mito- chondrial oxidative phosphorylation (OXPHOS) dependence and metabolic heterogeneity establishes its thera- peutic potential following systemic …
Cell Aggregation Activates Small Gtpase Rac1 And Induces Cd44 Cleavage By Maintaining Lipid Raft Integrity, Dong Li, Younhee Park, Hami Hemati, Xia Liu
Cell Aggregation Activates Small Gtpase Rac1 And Induces Cd44 Cleavage By Maintaining Lipid Raft Integrity, Dong Li, Younhee Park, Hami Hemati, Xia Liu
Markey Cancer Center Faculty Publications
Lipid rafts are highly ordered membrane domains that are enriched in cholesterol and glycosphingolipids and serve as major platforms for signal transduction. Cell detachment from the extracellular matrix (ECM) triggers lipid raft disruption and anoikis, which is a barrier for cancer cells to metastasize. Compared to single circulating tumor cells (CTCs), our recent studies have demonstrated that CD44-mediatd cell aggregation enhances the stemness, survival and metastatic ability of aggregated cells. Here, we investigated whether and how lipid rafts are involved in CD44-mediated cell aggregation. We found that cell detachment, which mimics the condition when tumor cells detach from the ECM …
November / December 2023, Randy Curry, Cindy Brooks
November / December 2023, Randy Curry, Cindy Brooks
RURAL ROCKS
This is the November & December 2023 issue of Rural Rocks from the SWOSU College of Pharmacy.
Prevalence Of Substance Use Among Lesbian, Gay, And Bisexual High School Students In 2019 Vs. 2021, Jordyn Lee, Elisabeth Hayes, Adam Wyatt
Prevalence Of Substance Use Among Lesbian, Gay, And Bisexual High School Students In 2019 Vs. 2021, Jordyn Lee, Elisabeth Hayes, Adam Wyatt
Nursing & Health Sciences Research Journal
Background: Studies suggest that LGBTQ+ (lesbian, gay, bisexual, transgender, queer/questioning, plus) youth are at increased risk of engaging in alcohol and substance use. The COVID-19 pandemic forced many students to isolate in 2020 and 2021, and the impacts of this have been purported to be detrimental. This study examines the prevalence of alcohol and substance use among lesbian, gay, and bisexual (LGB) U.S. high school students before the pandemic in 2019 versus 2021. Methods: This cross-sectional descriptive study used results from the 2019 Youth Risk Behavior Survey (YRBS) and the 2021 Adolescent Behavior and Experiences Survey (ABES). The 2019 YRBS …
Residual Pulmonary Vascular Obstruction Following Mechanical Thrombectomy For Submassive Pulmonary Embolism: A Single-Center Analysis, Brian Stegman, Thom G. Dahle, Wade Schmidt, Jacob R. Dutcher, Tanya Glenz
Residual Pulmonary Vascular Obstruction Following Mechanical Thrombectomy For Submassive Pulmonary Embolism: A Single-Center Analysis, Brian Stegman, Thom G. Dahle, Wade Schmidt, Jacob R. Dutcher, Tanya Glenz
Articles
Background:
Residual pulmonary vascular obstruction (RPVO) following pulmonary embolism (PE) is associated with residual dyspnea, recurrent venous thromboembolism, and chronic thromboembolic pulmonary hypertension. Historically, acute PE treated with anticoagulation alone results in high rates of significant RPVO. Contemporary treatment of submassive PE often involves catheter-based interventions, including mechanical thrombectomy (MT), although their relation to RPVO is not characterized. In this study, we aimed to evaluate the rate of greater than or equal to 10% RPVO in patients treated with MT.
Methods:
Twenty consecutive patients with submassive PE in a single center underwent MT and subsequent planar ventilation/perfusion scintigraphy scan at …
Evaluation Of Efferent Unmasking Using Cortical Auditory-Evoked Potentials, Donguk Lee
Evaluation Of Efferent Unmasking Using Cortical Auditory-Evoked Potentials, Donguk Lee
Theses and Dissertations (ETD)
Purpose. All human beings, regardless of whether they have hearing impairments or not, face difficulties in detecting signals in the presence of background noise. To cope with such situations, people can enhance their performance by either increasing the signal levels or reducing the noise levels, which in turn increases the signal-to-noise ratios (SNRs). SNRs play a crucial role in determining one's speech perception abilities. For instance, if the noise levels are high, individuals may raise their voices or decrease their distance from the source to amplify the signal levels, thereby increasing the SNR. However, in real-life situations, individuals may not …
Advancing Suicide Intervention Strategies For Teens (Assist): Study Protocol For A Multisite Randomised Controlled Trial, Molly Adrian, Elizabeth Mccauley, Robert Gallop, Jack Stevens, David A. Jobes, Jennifer Crumlish, Barbara Stanley, Gregory K. Brown, Kelly L. Green, Jennifer L. Hughes, Jeffrey A. Bridge
Advancing Suicide Intervention Strategies For Teens (Assist): Study Protocol For A Multisite Randomised Controlled Trial, Molly Adrian, Elizabeth Mccauley, Robert Gallop, Jack Stevens, David A. Jobes, Jennifer Crumlish, Barbara Stanley, Gregory K. Brown, Kelly L. Green, Jennifer L. Hughes, Jeffrey A. Bridge
Mathematics Faculty Publications
Introduction: Brief interventions that reduce suicide risk following youth's experience with acute care due to suicidality are needed. Methods and analysis: The study will use a three-arm randomised controlled trial designed to test the effectiveness of the Safety Planning Intervention with structured follow-up (SPI+) and the Collaborative Assessment and Management of Suicidality (CAMS) compared with enhanced usual care. The primary outcomes measure will be suicidal events, defined as death by suicide, attempted suicide, preparatory acts toward imminent suicidal behaviour or suicidal ideation resulting in a change in emergency evaluation or inpatient admission. Secondary measures will be the number of suicide …
The Impact Of Neighborhood Socioeconomic Disadvantage On Operative Outcomes After Single-Level Lumbar Fusion, Grace Y. Ng, Ritesh Karsalia, Ryan S. Gallagher, Austin J. Borja, Jianbo Na, Scott Mcclintock, Neil R. Malhotra
The Impact Of Neighborhood Socioeconomic Disadvantage On Operative Outcomes After Single-Level Lumbar Fusion, Grace Y. Ng, Ritesh Karsalia, Ryan S. Gallagher, Austin J. Borja, Jianbo Na, Scott Mcclintock, Neil R. Malhotra
Mathematics Faculty Publications
INTRODUCTION: The relationship between socioeconomic status and neurosurgical outcomes has been investigated with respect to insurance status or median household income, but few studies have considered more comprehensive measures of socioeconomic status. This study examines the relationship between Area Deprivation Index (ADI), a comprehensive measure of neighborhood socioeconomic disadvantage, and short-term postoperative outcomes after lumbar fusion surgery. METHODS: 1861 adult patients undergoing single-level, posterior-only lumbar fusion at a single, multihospital academic medical center were retrospectively enrolled. An ADI matching protocol was used to identify each patient's 9-digit zip code and the zip code-associated ADI data. Primary outcomes included 30- and …
Delirium Education For Family Caregivers Of Patients In The Intensive Care Unit: A Pilot Study, Amanda Wheeler, Elise Bloch, Sarah Blaylock, James Root, Kateriza Ibanez, Newman Newman, Jose Diarte, Louis P. Voigt
Delirium Education For Family Caregivers Of Patients In The Intensive Care Unit: A Pilot Study, Amanda Wheeler, Elise Bloch, Sarah Blaylock, James Root, Kateriza Ibanez, Newman Newman, Jose Diarte, Louis P. Voigt
Occupational Therapy Faculty Publications
Objectives
Delirium, an acute change in mental state, seen in hospitalized older adults is a growing public health concern with implications for both patients and caregivers; however, there is minimal research on educating caregivers about delirium. Utilizing family caregivers to assist with delirium management in acute care settings demonstrates improved health outcomes supporting the need for patient and family centered care. The primary aims of the study were to determine feasibility of implementing a delirium education video for caregivers of patients in an adult oncology intensive care unit and compare delirium knowledge to caregivers in a control group.
Methods
A …
Comparing And Contrasting Nursing In World War I And World War Ii, Adrianna Staniszewski
Comparing And Contrasting Nursing In World War I And World War Ii, Adrianna Staniszewski
University Libraries Award for Undergraduate Research
No abstract provided.
The Psychiatrist’S Gambit: Using Chess As A Novel Means To Manage Treatment Refractory Catatonia, Joseph Michael Ahearn Iii, Md, Manny Villar
The Psychiatrist’S Gambit: Using Chess As A Novel Means To Manage Treatment Refractory Catatonia, Joseph Michael Ahearn Iii, Md, Manny Villar
Department of Psychiatry
No abstract provided.
Assessment Of Care-Arrangement Of People With Dementia In Karachi By 10/66 Protocol, Qurat Ul Ain Khan
Assessment Of Care-Arrangement Of People With Dementia In Karachi By 10/66 Protocol, Qurat Ul Ain Khan
Pakistan Journal of Neurological Sciences (PJNS)
Background and objective:
Pakistan is a low middle-income country (LMIC) in South Asia with a rising aging population. This study aimed to understand care-arrangement and resources of people with dementia (PWD) in Karachi, Pakistan.
Methods:
This cross-sectional mixed-method (qualitative and quantitative) study was carried out using 10/66 protocol for dementia patients. Data collection for the study was done from September 2016 till August 2017.This assessed characteristics of patients and caregivers, the economic impact of caregiving, and resources available to care for people with dementia (PWD).
Results:
One-hundred-nineteen PWD and their caregivers were included in the study. The average gross national …
Artificial Intelligence And Neurosurgery: A Revolution In The Field, Ahtesham Khizar
Artificial Intelligence And Neurosurgery: A Revolution In The Field, Ahtesham Khizar
Pakistan Journal of Neurological Sciences (PJNS)
Artificial Intelligence (AI) is being used in the field of neurosurgery for improving patient outcomes, reducing the risk of complications, and increasing the efficiency of surgical procedures. AI algorithms can analyze patient data, plan surgical procedures, guide surgical instruments, monitor brain activity, and improve post-operative care. The benefits of incorporating AI into neurosurgical practice include pre-operative planning, intraoperative navigation, real-time monitoring, and post-operative care. AI is already being used in neurosurgery for image segmentation, surgical planning, intraoperative navigation, real-time monitoring, and predictive analytics. The potential applications of AI in neurosurgery include personalized medicine, virtual reality, robotic surgery, predictive analytics, and …
Evaluation Of Stroke Awareness And Risk Factor Prevalence Among Students At A Public Sector University In Quetta, Anjum Farooq, Muhammad Essa, Muhammad Saleem, Abdul Aleem, Muhammad Rizwan
Evaluation Of Stroke Awareness And Risk Factor Prevalence Among Students At A Public Sector University In Quetta, Anjum Farooq, Muhammad Essa, Muhammad Saleem, Abdul Aleem, Muhammad Rizwan
Pakistan Journal of Neurological Sciences (PJNS)
Background and Objective:
Stroke is the leading cause of death and disability. Improving stroke knowledge among medical students will help to improve stroke care and its prevention. This study aims to evaluate the prevalence of risk factors and stroke awareness among university students.
Methods:
This cross-sectional study was conducted among students at Sardar Bahadur Khan Women's University in Quetta. An eleven-question multiple-choice survey was administered to assess participants' knowledge of stroke-related concepts. The initial study was conducted using descriptive statistics. Additionally, a supplementary screening for common risk factors linked to stroke was included in the study, which involved blood pressure, …
Frequency Of Risk Factors For Stroke In Young Pakistani Population, Faizan Aslam, Atif Maqsood, Adeel Rauf, Kashif Nawaz, Azam Aslam
Frequency Of Risk Factors For Stroke In Young Pakistani Population, Faizan Aslam, Atif Maqsood, Adeel Rauf, Kashif Nawaz, Azam Aslam
Pakistan Journal of Neurological Sciences (PJNS)
Background and Objective:
There is paucity of data regarding risk factors of stroke in young Pakistanis. The objective of this study was to identify the frequency of risk factors for ischemic stroke in the young Pakistani population.
Methods:
This was a retrospective Cross sectional study conducted at Aziz Fatima Hospital Neurology outpatient’s department between January 2022 to April 2022. All patients presenting with an ischemic stroke within the past month and age between 20 and 49 years were included. Data was collected from patient notes using a table which listed the patient’s demographic information and risk factors. All the patients …
Letter From The Vice President Of Research And Innovation, The Mcnair Team
Letter From The Vice President Of Research And Innovation, The Mcnair Team
McNair Scholars Research Journal
No abstract provided.
Crushability Analysis Of Immediate-Release Oral Tablets And Capsules Approved By Fda In 2020-2022, Kamaladdin Saei, Anne Schweighardt, Fang Zhao
Crushability Analysis Of Immediate-Release Oral Tablets And Capsules Approved By Fda In 2020-2022, Kamaladdin Saei, Anne Schweighardt, Fang Zhao
Doctoral External Publications
Healthcare providers often need to explore dosage form options for patients who are unable to swallow whole tablets or capsules. Most newly approved immediate-release (IR) oral solid drugs carry a "do not crush" warning or similar language in their labeling due to the lack of supporting clinical data. A 2021 publication by Uttaro et al. presented a crushability analysis strategy for risk assessment and demonstrated its utility for the questionable drugs on the ISMP do-not-crush list. This study aimed to extend the crushability analysis to newly FDA-approved drugs.
What Role Do Parents And Acculturation Play In Chinese Female International High School Students’ Mental Health?, You Wu
Doctoral Dissertations
This study examines the challenges and mental health issues faced by Chinese female international students in private Catholic female high schools in the U.S. It explores three main areas: the types of acculturation challenges students face, the impact of these challenges on their mental health, and the role of parental communication in shaping students' and parents' perceptions of acculturation and mental health. Using qualitative methods, the research involved interviews with nine students and five parents from a girls' Catholic high school in California. Data were collected via narrative-inspired Zoom interviews, and analyzed using phenomenological principles, focusing on understanding the lived …
A Word From The Writing Team (December 2023), Pam Walter, Mfa, Liz Declan, Ma, Mfa
A Word From The Writing Team (December 2023), Pam Walter, Mfa, Liz Declan, Ma, Mfa
A Word From the Writing Team (Newsletter)
This issue includes:
- Writing Retreats Happens This Friday, December 1st
- The OPWPC Canvas Page Offers Helpful Tools
- The Yeo Writing Deadline is December 31, 2023!
- Publication Spotlight
- AI and Publishing is a Hot Topic
- Scott Memorial Library Renovations Continue
- Wiley Open Access Fees Waived for Jefferson Authors
Protocol For Intervention Development To Improve Adolescent Perinatal Mental Health In Kenya And Mozambique: The Inspire Project, Kethakie Lamahewa, Sally Griffin, Nadine Seward, Marleen Temmerman, Jonathan West, Málica De Melo, Elizabeth Raby, Aline Alonso, Bethan Burnside, Fernando Chissale
Protocol For Intervention Development To Improve Adolescent Perinatal Mental Health In Kenya And Mozambique: The Inspire Project, Kethakie Lamahewa, Sally Griffin, Nadine Seward, Marleen Temmerman, Jonathan West, Málica De Melo, Elizabeth Raby, Aline Alonso, Bethan Burnside, Fernando Chissale
Obstetrics and Gynaecology, East Africa
Introduction: Mental health interventions have traditionally been developed by clinicians and researchers without the meaningful engagement and partnership with those who would receive, deliver, and fund them. Recent progress has highlighted the importance of the co-design of interventions, through stakeholder participation, as a means of increasing the integration of mental health interventions into existing health, education, and social care systems. This protocol describes the pre-implementation phase of the INSPIRE (Innovative approaches to adolescent perinatal wellbeing) project which aims to identify challenges, and design and test interventions to promote mental wellbeing and good mental health of adolescent girls during pregnancy and …
Brain-Wide Correspondence Of Neuronal Epigenomics And Distant Projections, Jingtian Zhou, Zhuzhu Zhang, May Wu, Hanqing Liu, Yan Pang, Anna Bartlett, Zihao Peng, Wubin Ding, Angeline Rivkin, Will N Lagos, Elora Williams, Cheng-Ta Lee, Paula Assakura Miyazaki, Andrew Aldridge, Qiurui Zeng, J L Angelo Salinda, Naomi Claffey, Michelle Liem, Conor Fitzpatrick, Lara Boggeman, Zizhen Yao, Kimberly A Smith, Bosiljka Tasic, Jordan Altshul, Mia A Kenworthy, Cynthia Valadon, Joseph R Nery, Rosa G Castanon, Neelakshi S Patne, Minh Vu, Mohammad Rashid, Matthew Jacobs, Tony Ito, Julia Osteen, Nora Emerson, Jasper Lee, Silvia Cho, Jon Rink, Hsiang-Hsuan Huang, António Pinto-Duartec, Bertha Dominguez, Jared B Smith, Carolyn O'Connor, Hongkui Zeng, Shengbo Chen, Kuo-Fen Lee, Eran A Mukamel, Xin Jin, M Margarita Behrens, Joseph R Ecker, Edward M Callaway
Brain-Wide Correspondence Of Neuronal Epigenomics And Distant Projections, Jingtian Zhou, Zhuzhu Zhang, May Wu, Hanqing Liu, Yan Pang, Anna Bartlett, Zihao Peng, Wubin Ding, Angeline Rivkin, Will N Lagos, Elora Williams, Cheng-Ta Lee, Paula Assakura Miyazaki, Andrew Aldridge, Qiurui Zeng, J L Angelo Salinda, Naomi Claffey, Michelle Liem, Conor Fitzpatrick, Lara Boggeman, Zizhen Yao, Kimberly A Smith, Bosiljka Tasic, Jordan Altshul, Mia A Kenworthy, Cynthia Valadon, Joseph R Nery, Rosa G Castanon, Neelakshi S Patne, Minh Vu, Mohammad Rashid, Matthew Jacobs, Tony Ito, Julia Osteen, Nora Emerson, Jasper Lee, Silvia Cho, Jon Rink, Hsiang-Hsuan Huang, António Pinto-Duartec, Bertha Dominguez, Jared B Smith, Carolyn O'Connor, Hongkui Zeng, Shengbo Chen, Kuo-Fen Lee, Eran A Mukamel, Xin Jin, M Margarita Behrens, Joseph R Ecker, Edward M Callaway
Faculty, Staff and Student Publications
Single-cell analyses parse the brain’s billions of neurons into thousands of ‘cell-type’ clusters residing in different brain structures1. Many cell types mediate their functions through targeted long-distance projections allowing interactions between specific cell types. Here we used epi-retro-seq2 to link single-cell epigenomes and cell types to long-distance projections for 33,034 neurons dissected from 32 different regions projecting to 24 different targets (225 source-to-target combinations) across the whole mouse brain. We highlight uses of these data for interrogating principles relating projection types to transcriptomics and epigenomics, and for addressing hypotheses about cell types and connections related to genetics. …
Does What Doesn’T Kill You Make You Stronger? Examining The Effects Of Resilience And Functional Outcomes On Post-Traumatic Growth In Adults With Acquired Disability, Dominique Renee Ghirardi M.S.
Does What Doesn’T Kill You Make You Stronger? Examining The Effects Of Resilience And Functional Outcomes On Post-Traumatic Growth In Adults With Acquired Disability, Dominique Renee Ghirardi M.S.
Theses and Dissertations
Disabilities acquired in adulthood are often unexpected and disruptive because a loss of functioning can affect one’s ability to maintain employment, pursue their interests, and participate in social activity without assistance or accommodation. This is especially true for those who experience a life-altering injury or develop a chronic health condition between the ages of 18 and 64, as they likely have not planned for the financial and social adjustments that life with a disability involves. However, factors such as post-traumatic growth can reveal the extent to which someone experiences personal growth and improvement in the wake of a traumatic and …