Medicine and Health Sciences Commons^™

Microbial Science Research In The Post-Covid Environment, Nguyen K Nguyen, Carey-Ann D Burnham, Arturo Casadevall, Mary K Estes, Rebecca V Ferrell, Suzanne M J Fleiszig, Speakers, Moderators, And Panelists Of The Asm Virtual Symposium: Microbial Science Research In The Post-Covid Environment

Faculty, Staff and Students Publications

Since early 2020, the world has witnessed the unprecedented accomplishments of the scientific community in the fight against the coronavirus disease 2019 (COVID-19) pandemic. In the meantime, we also learned valuable lessons and recognized the challenges that hindered our successes. In this article, we synthesize the ideas discussed at the ASM Virtual Symposium: Microbial Science Research in the Post-COVID Environment on 10 November 2020. We propose three new approaches that microbiology researchers can embrace to overcome these challenges. Moreover, we suggest broad systematic changes to focus on social impacts, teamwork, and diversity, equity, and inclusion. We believe these values are …

Pregnancy And Substance Use, Elise Withers, Krista Thompson, Emily Hamilton, Maren Wright Voss

All Current Publications

The use of alcohol and other harmful substances, such as cocaine, opioids, and marijuana during pregnancy has increased over the last decades (Sebastiani et al., 2018). Using these substances can be very harmful to the unborn baby and mother (Viteri et al., 2015). This fact sheet covers (1) the consequences of substance use and (2) the current recommendations for substance use during pregnancy.

Benign Myoepithelioma Of The Soft Palate: An Unusual Clinical Entity, Marianna Guadalupe Mireles, Angelica Julián, Fabiola Salgado-Chavarría, Guillermo Manuel González

Faculty, Staff and Students Publications

Myoepitheliomas are rare benign tumours that affect the exocrine glands and are sporadically located in the salivary glands. The most common location of myoepithelioma in the oral cavity is the parotid gland and it is seldom encountered in the palate. The diagnosis of this entity is challenging since its clinical presentation may resemble those of more common neoplasms, rendering a complex histopathological diagnosis. The aim of the present case report is to describe an unusual case of myoepithelioma of the soft palate in a male patient, which developed as an asymptomatic, slowly growing mass. The tumour was assessed with histopathological …

Strategies For Treatment Of Bilateral Impacted High Canine–Lateral Incisor Transposition: A Stepwise Approach, Yun-Yun Wu, Fu-Hui Tsai, Jui-Hsien Yang

Taiwanese Journal of Orthodontics

To achieve a satisfactory outcome for transposed impacted teeth, the esthetic assessment and functional rehabilitation should be considered from both the orthodontic and periodontic perspective. In this case, a stepwise approach was used for both surgical uncovering and orthodontic treatment to manage the soft and hard tissue of transposed high canine. The case involved a girl aged 11 years and 7 months with bilateral high impacted canine–lateral incisor transposition. The impacted canines were first uncovered with the closed eruption technique and then moved horizontally to a normal sequence in the arch. Apically repositioned flap surgery was then performed, and the …

Management Of Unilateral Maxillary Canine Impaction, Maureen Antolis, Krisnawati E. Tarman

Taiwanese Journal of Orthodontics

Maxillary canine is an essential part of teeth for smile esthetic and function. Orthodontic treatment for patient with impacted maxillary canine is considered to be more complex and require good biomechanical control during traction. This case report describes an orthodontic treatment of a 17-year old female patient with unilateral maxillary canine impaction on the left side. Orthodontic traction was used to guide the canine into normal occlusion. The orthodontic treatment had been completed within 19 months and successfully obtained favourable esthetic and stable occlusion.

Compare Two Methods Of Dental Arch Length Measurements On Digital Dental Models, Ying-Chen Chen, Carol Yi-Hsuan Chen, Ellen Wen-Ching Ko

Taiwanese Journal of Orthodontics

Purpose: Accurate space discrepancy evaluation is important in treatment planning. Straight-line segments and brass wire method are the most common methods in arch length assessment. However, using segments causes underestimation, while more reliable brass wire method shows lower reproducibility. The aim of our study is (1) to compare the difference between conventional segmental distance method (SD) and a new method, ideal arch form (IA), and (2) to assess the reproducibility and reliability of two methods by means of digital models. Materials and methods: Thirty sets of digital dental models presented full permanent dentition and Angle’s Class III malocclusion were included. …

Evaluation Of Patients’ Experiences After Microimplant-Assisted Rapid Palatal Expansion (Marpe) Treatment, Huei-Rou Tsai, Kwok-Hing Ho, Chih-Wei Wang, Kai-Long Wang, Shun-Chu Hsieh, Heng-Ming Chang

Taiwanese Journal of Orthodontics

Purpose: Various microimplant- assisted rapid palatal expansion (MARPE) appliances were developed in these years. By applying this procedure, maxillary transverse deficiencies can be corrected in adults with limited dental tipping. However, some undesirable effects could happen during treatment. In this study, we aimed to record the incidence of any adverse effect or complication. Pain score was also measured during treatment. Patients and Methods: Twenty-nine patients (22.8 ± 8.6 years old) with 13 males and 16 females were enrolled. Clinical photographs, radiographs and cone-beam computed tomography were taken before insertion of MARPE and after expansion. Interview was conducted by one orthodontist …

Etiology, Development, Diagnosis And Considerations In Treatment Of The Class Ii, Division 2 Malocclusion: What The Clinician Should Know About This Malocclusion (Part I), Ib Leth Nielsen

Taiwanese Journal of Orthodontics

The Class II Division 2 malocclusion has puzzled a great many orthodontists over the years. How does it develop and how does it get its characteristic appearance? What are the etiological factors that lead to the typical arrangement of the front teeth? How should we treat it? These are just a few of the many questions that still need answers. In this article we will discuss the etiology and development of this malocclusion and in Part II provide some guidelines for timing and correction of the Class II, Div. 2 malocclusion that are applicable to most cases. We shall also …

Compassionate Indifference, Judith Sullivan

Journal of Transformative Touch

ABSTRACT

How to turn a not-so-good treatment into an excellent treatment with presence, relaxation and compassionate indifference.

Concurrent Covid-19 Infection In Children With Acute Appendicitis: A Report Of Three Cases, Maximo J. Acevedo, Dylan Steffey, Johanne E. Dillon, James T. Lee, David J. Worhunsky

Radiology Faculty Publications

Literature describing patients with concomitant COVID-19 infection with acute appendicitis in pediatric patients is growing, and understanding the clinical picture of such patients is relevant in their treatment. We report 3 male children who were surgically treated for acute appendicitis and had concomitant SARS-CoV-2 infection. Our first patient was a 12-year-old male who presented with symptoms indicative of appendicitis but no respiratory symptoms associated with COVID-19 (eg cough, shortness of breath). Laboratory evaluation revealed leukopenia and an elevated C-reactive protein; imaging was consistent with acute appendicitis and an acute pulmonary viral infection. Though he lacked diffuse peritonitis on physical examination …

“The Clementine Collective”: A Corner Store Intervention Of Clementine Fruits In A High Need Neighborhood In Staten Island, New York, Heather Butts

Faculty of Health Care & Public Administration Publications

Individuals living in underserved neighborhoods face significant barriers to getting fresh produce. It has been extensively researched that providing individuals with fresh fruits and vegetables can have a positive physical and mental impact on the lives of individuals in underserved neighborhoods and the lives of their families. Unfortunately, individuals who reside in such neighborhoods are often viewed as not being motivated to consume fresh fruits and vegetables, even where barriers to eating such foods are removed. This study aims to determine whether, in the COVID-19 era, individuals in underserved neighborhoods would consume fresh fruits if presented with them in an …

2021-06-28_Michiganoverview_Covidschooloutbreak, Michigan Department Of Health & Human Services

Michigan COVID-19 Outbreak Reports

The School Outbreak Data page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173_102480---,00.html.

This report is created by the Michigan Department of Health & Human Services from data self-reported by local health departments. Data is updated every week.

In accordance with the Council of State and Territorial Epidemiologists’ outbreak definition, schools that have been found by their local health department to have two (2) or more COVID-19 cases who may have shared exposure at the school grounds and are not from the same household (with the exception of dorms and off-campus housing) are included. If your child’s school is …

2021-06-28_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled. It is updated Monday - Friday.
This report is provisional and subject to change. City of Detroit and Wayne County are reported separately. MDHHS began tracking probable cases April 5, 2020. FCI indicates federal correctional institute. MDOC indicates Michigan Department of Corrections. Diagnostic tests, including nucleic acid amplification/real-time polymerase chain reaction (NAAT/RT-PCR) and rapid virus antigen detection point of …

2021-06-28_Michiganoverview_Covidcounts, Michigan Department Of Health & Human Services

Michigan COVID-19 Confirmed Cases by Date of Onset Data

Data was downloaded as an Excel spreadsheet which appeared in the Public Use Datasets section under the Cumulative Data link of Michigan's Coronavirus webpage, under the url https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173---,00.html.

Cases are aggregated by the date of onset of COVID-19 symptoms, if known, otherwise by laboratory specimen date if known, otherwise by case referral date. Deaths are aggregated by the date of death if known, otherwise by the last date of a change to the case status.

2021-06-28_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …

2021-06-28_Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

Contains the tables Statewide Hospital Capacity Report for COVID-19, COVID-19 Metrics, Statewide Hospital Available PPE Tracking for COVID-19, as well as the tables PPE Days On Hand and Patient Census.

Direct Maternal Morbidity And The Risk Of Pregnancy-Related Deaths, Stillbirths, And Neonatal Deaths In South Asia And Sub-Saharan Africa: A Population-Based Prospective Cohort Study In 8 Countries, Imran Ahmed, Shabina Ariff, Zulfiqar Ahmed Bhutta, Muhammad Ilyas, Fyezah Jehan, Usma Mehmood, Karim Muhammad, Muhammad Imran Nisar, Sajid Bashir Soofi, Yaqub Wasan, Anita K. M. Zaidi

Woman and Child Health

Background: Maternal morbidity occurs several times more frequently than mortality, yet data on morbidity burden and its effect on maternal, foetal, and newborn outcomes are limited in low- and middle-income countries. We aimed to generate prospective, reliable population-based data on the burden of major direct maternal morbidities in the antenatal, intrapartum, and postnatal periods and its association with maternal, foetal, and neonatal death in South Asia and sub-Saharan Africa.
Methods and findings: This is a prospective cohort study, conducted in 9 research sites in 8 countries of South Asia and sub-Saharan Africa. We conducted population-based surveillance of women of reproductive …

Responding To The Call: Building A Training Program To Diversify The Academy In Alzheimer's Disease Research, Lucy Annang Ingram Phd, Mph, Marvella E. Ford, Christiana L. Johnson, Brianna Ashford-Carroll, Quentun Mccollum, Daniela B. Friedman Ph.D., Sue Ellen Levkoff

Faculty and Staff Publications

Alzheimer's disease and related dementias (ADRD) are at the forefront of the United States (US) public health agenda due to their tremendous human and financial burden. Further, disproportionately high ADRD rates among racial/ethnic minorities require incorporating the unique perspectives of racially and ethnically diverse scientists, which will necessitate diversifying the scientific workforce that investigates disparities in aging. The purpose of this paper is to describe the training and mentorship initiatives of the National Institute on Aging (NIA)-funded Carolina Center on Alzheimer's Disease and Minority Research, emphasizing lessons learned from our engagement with underrepresented minority and minoritized (URM) Scientists. We highlight …

Emergency Department - Community Partnership To Coordinate Older Adults Falls Prevention Programs, Suzanne Ryer, Ann Gallo, Adam Perry, Michael Malone

Journal of Geriatric Emergency Medicine

Abstract

Falls and injurious falls are common causes for emergency department visits in older adults. Prior literature describing ED care of older adults has focused on the patients' injuries and their ED care. There is a gap in the literature describing community- based falls prevention strategies and interventions deployed by community organizations, beyond health systems. We identified variation in approaches to older adults among paramedic programs from one community to the next within Milwaukee County, Wisconsin. We also noted no organized falls prevention program spanning all communities, emergency departments and health systems in the county. We describe the implementation of …

Impact Of Covid-19 On Family Planning, Bakhtawar M H. Khowaja, Quratulain Shalwani

Department of Obstetrics & Gynaecology

No abstract provided.

Emerging Advances Of Nanotechnology In Drug And Vaccine Delivery Against Viral Associated Respiratory Infectious Diseases (Varid), Amir Seyfoori, Mahdieh Shokrollahi Barough, Pooneh Mokarram, Mazaher Ahmadi, Parvaneh Mehrbod, Alireza Sheidary, Tayyebeh Madrakian, Mohammad Kiumarsi, Tavia Walsh, Kielan D Mcalinden, Chandra C Ghosh, Pawan Sharma, Amir A Zeki, Saeid Ghavami, Mohsen Akbari

Center for Translational Medicine Faculty Papers

Viral-associated respiratory infectious diseases are one of the most prominent subsets of respiratory failures, known as viral respiratory infections (VRI). VRIs are proceeded by an infection caused by viruses infecting the respiratory system. For the past 100 years, viral associated respiratory epidemics have been the most common cause of infectious disease worldwide. Due to several drawbacks of the current anti-viral treatments, such as drug resistance generation and non-targeting of viral proteins, the development of novel nanotherapeutic or nano-vaccine strategies can be considered essential. Due to their specific physical and biological properties, nanoparticles hold promising opportunities for both anti-viral treatments and …

The Role Of White Matter In The Neural Control Of Swallowing: A Systematic Review, Ann Alvarenga, Rachel Hahn Arkenberg, Bethany Mcgowan, Hu Cheng, Georgia A. Malandraki

Purdue University Libraries Open Access Publishing Fund

Background: Swallowing disorders (dysphagia) can negatively impact quality of life and health. For clinicians and researchers seeking to improve outcomes for patients with dysphagia, understanding the neural control of swallowing is critical. The role of gray matter in swallowing control has been extensively documented, but knowledge is limited regarding the contributions of white matter. Our aim was to identify, evaluate, and summarize the populations, methods, and results of published articles describing the role of white matter in neural control of swallowing.

Methods: We completed a systematic review with a multi-engine search following PRISMA-P 2015 standards. Two authors screened articles and …

The Value Of Republishing Scientific Literature In Institutional Repositories, Sue Ann Gardner, Linnea Fredrickson, Paul Royster

University of Nebraska-Lincoln Libraries: Presentations

Background: The University of Nebraska-Lincoln University Libraries institutional repository was founded in 2005 on the Digital Commons platform. It currently contains more than 118,000 full-text scholarly works that have been downloaded over 73,000,000 times.

Problem that drove the project: Older scientific literature may only occasionally circulate from university library collections or be purchased by readers from remaindered publishers' stock.

Methods: This research will employ statistical analyses to demonstrate the value of making available four series of scientific literature in the University of Nebraska-Lincoln University Libraries Digital Commons: Insecta Mundi, the Nebraska Bird Review, the Transactions of the Nebraska …

Risk Of Early-Onset Dementia Among Persons With Tinnitus: A Retrospective Case–Control Study, Yen-Fu Cheng, Sudha Xirasagar Mbbs. Ph.D., Tzong- Han Yang, Chuan-Song Wu, Yi-Wei Kao, Herng-Ching Lin

Faculty Publications

Higher rates of poor cognitive performance are known to prevail among persons with tinnitus in all age groups. However, no study has explored the association between tinnitus and early-onset dementia. We hypothesize that tinnitus may precede or occur concurrently with subclinical or early onset dementia in adults younger than 65 years of age. This case–control study used data from the Taiwan National Health Insurance Research Database, identifying 1308 patients with early-onset dementia (dementia diagnosed before 65 years of age) and 1308 matched controls. We used multivariable logistic regressions to estimate odds ratios (ORs) for prior tinnitus among patients with dementia …

Restoration Of The Molecular Clock Is Tumor Suppressive In Neuroblastoma, Myrthala Moreno-Smith, Giorgio Milazzo, Ling Tao, Baharan Fekry, Bokai Zhu, Mahmoud A Mohammad, Simone Di Giacomo, Roshan Borkar, Karthik Reddy Kami Reddy, Mario Capasso, Sanjeev A Vasudevan, Pavel Sumazin, John Hicks, Nagireddy Putluri, Giovanni Perini, Kristin Eckel-Mahan, Thomas P Burris, Eveline Barbieri

Children’s Nutrition Research Center Staff Publications

MYCN activation is a hallmark of advanced neuroblastoma (NB) and a known master regulator of metabolic reprogramming, favoring NB adaptation to its microenvironment. We found that the expression of the main regulators of the molecular clock loops is profoundly disrupted in MYCN-amplified NB patients, and this disruption independently predicts poor clinical outcome. MYCN induces the expression of clock repressors and downregulates the one of clock activators by directly binding to their promoters. Ultimately, MYCN attenuates the molecular clock by suppressing BMAL1 expression and oscillation, thereby promoting cell survival. Reestablishment of the activity of the clock activator RORα via its genetic …

Profiling Pretomanid As A Therapeutic Option For Tb Infection: Evidence To Date., Stephani L. Stancil, Fuad Mirzayev, Susan M. Abdel-Rahman

Manuscripts, Articles, Book Chapters and Other Papers

Tuberculosis (TB) is the most deadly infectious disease globally. Although most individuals achieve a cure, a substantial portion develop multi-drug resistant TB which is exceedingly difficult to treat, and the number of effective agents is dwindling. Development of new anti-tubercular medications is imperative to combat existing drug resistance and accelerate global eradication of TB. Pretomanid (PA-824) represents one of the newest drug classes (ie, nitroimidazooxazines) approved in 2019 by the United States Food and Drug Administration as part of a multi-drug regimen (with bedaquiline and linezolid, BPaL) and recommended by the World Health Organization (WHO) to treat extensively-resistant (XR-TB) and …

A Multi-Faceted Approach To Understanding Acceptability Of Docs K-5: A Qualitative Analysis, Andrea Guarnieri

USF Tampa Graduate Theses and Dissertations

This qualitative study investigated the acceptability of DOCS K-5, a behavior parenting program adapted for parents of elementary aged children. Despite proven efficacy in preventing maladaptive behaviors, parenting programs have historically suffered from low attendance and engagement. Participants (N = 13) attending the pilot DOCS K-5 program took part in six group interviews while enrolled in the program to examine the facilitators and barriers to attendance, perceived effectiveness, and collateral benefits received from participation in the program. This study considered possible cognitive, affective, instructional, and pragmatic facilitators or barriers to attendance and engagement. Participants described motivations to learn various types …

Tocilizumab And Covid-19: A Meta-Analysis Of 2120 Patients With Severe Disease And Implications For Clinical Trial Methodologies, Azza Sarfraz, Zouina Sarfraz, Muzna Sarfraz, Hinna Aftab, Zainab Pervaiz

Department of Paediatrics and Child Health

Background/aim: Since the outbreak of the COVID-19, numerous therapies to counteract this severe disease have emerged. The benefits of Tocilizumab for severely infected COVID-19 patients and the methodologies of ongoing clinical trials are explored.
Materials and methods: A systematic search adhering to PRISMA guidelines was conducted in PubMed, Cochrane Central, medRxiv, and bioRxiv using the following keywords: “Tocilizumab,” “Actemra,” “COVID-19.” An additional subsearch was conducted on Clinicaltrials.gov to locate ongoing tocilizumab trials.
Results: A total of 13 studies were included in the meta-analysis comprising 2120 patients. The treatment group had lower mortality compared to the control group (OR = 0.42, …

Covid-19 And The Impact On Rural And Black Church Congregants: Results Of The C-M-C Project, Lovoria B. Williams, Anita F. Fernander, Tofial Azam, Maria L. Gomez, Junghee Kang, Cassidy L. Moody, Hannah Bowman, Nancy E. Schoenberg

Clinical and Translational Science Faculty Publications

The COVID‐19 pandemic has had devastating effects on Black and rural populations with a mortality rate among Blacks three times that of Whites and both rural and Black populations experiencing limited access to COVID‐19 resources. The primary purpose of this study was to explore the health, financial, and psychological impact of COVID‐19 among rural White Appalachian and Black nonrural central Kentucky church congregants. Secondarily we sought to examine the association between sociodemographics and behaviors, attitudes, and beliefs regarding COVID‐19 and intent to vaccinate. We used a cross sectional survey design developed with the constructs of the Health Belief and Theory …

Distress Evaluation In A Veteran Affairs Oncology Clinic, Reena Jayani, Ronald J. Markert, Amy Heard, Geetika Kumar

Internal Medicine Faculty Publications

Distress in oncology patients (pts) has a negative impact on quality of life, survival, and healthcare satisfaction. Higher distress leads to lower compliance with treatment and follow-up [1-8]. The 2012 American College of Surgeons Commission on Cancer (CoC) standard of care for oncology pts included an assessment for distress [1]. A screening process for distress allows the healthcare team to address these issues early and refer to appropriate resources [2-9]. This project was initiated to meet National Comprehensive Cancer Network (NCCN) and CoC standard of care, identify distress in veterans with cancer, and address these concerns. Patients who attended the …