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2021

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Full-Text Articles in Medicine and Health Sciences

Functional Differentiation In The Language Network Revealed By Lesion-Dymptom Mapping, William Matchin, Alexandra Basilakos, Dirk B. Den Ouden, Brielle C. Stark, Gregory Hickok, Julius Fridriksson Dec 2021

Functional Differentiation In The Language Network Revealed By Lesion-Dymptom Mapping, William Matchin, Alexandra Basilakos, Dirk B. Den Ouden, Brielle C. Stark, Gregory Hickok, Julius Fridriksson

Communication Sciences and Disorders Faculty Articles and Research

Theories of language organization in the brain commonly posit that different regions underlie distinct linguistic mechanisms. However, such theories have been criticized on the grounds that many neuroimaging studies of language processing find similar effects across regions. Moreover, condition by region interaction effects, which provide the strongest evidence of functional differentiation between regions, have rarely been offered in support of these theories. Here we address this by using lesion-symptom mapping in three large, partially-overlapping groups of aphasia patients with left hemisphere brain damage due to stroke (N = 121, N = 92, N = 218). We identified multiple measure by …


Evidence Of Myomir Regulation Of The Pentose Phosphate Pathway During Mechanical Load-Induced Hypertrophy, Taylor Valentino, Vandre C. Figueiredo, C. Brooks Mobley, John J. Mccarthy, Ivan J. Vechetti Jr. Dec 2021

Evidence Of Myomir Regulation Of The Pentose Phosphate Pathway During Mechanical Load-Induced Hypertrophy, Taylor Valentino, Vandre C. Figueiredo, C. Brooks Mobley, John J. Mccarthy, Ivan J. Vechetti Jr.

Physiology Faculty Publications

Many of the molecular and cellular mechanisms discovered to regulate skeletal muscle hypertrophy were first identified using the rodent synergist ablation model. This model reveals the intrinsic capability and necessary pathways of skeletal muscle growth in response to mechanical overload (MOV). Reminiscent of the rapid cellular growth observed with cancer, we hypothesized that in response to MOV, skeletal muscle would undergo metabolic programming to sustain increased demands to support hypertrophy. To test this hypothesis, we analyzed the gene expression of specific metabolic pathways taken from transcriptomic microarray data of a MOV time course. We found an upregulation of genes involved …


Coping In Pediatric Burn Survivors And Its Relation To Social Functioning And Self-Concept, Mira D H Snider, Sarah Young, Paul T Enlow, Corrine Ahrabi-Nejad, Ariel M Aballay, Christina L Duncan Dec 2021

Coping In Pediatric Burn Survivors And Its Relation To Social Functioning And Self-Concept, Mira D H Snider, Sarah Young, Paul T Enlow, Corrine Ahrabi-Nejad, Ariel M Aballay, Christina L Duncan

Department of Pediatrics Faculty Papers

Pediatric burn survivors experience increased risk for bullying, stigmatization, body image concerns, and problematic social functioning. Although coping behaviors are associated with engagement in social supports and positive self-concept in multiple pediatric illness populations, their relation has not been examined in pediatric burns. This study examined coping in relation to social functioning and self-concept in 51 pediatric burn survivors aged 7–17years (M=12.54; SD=2.65). Survivors and their caregivers completed the Child Coping Strategies Checklist (CCSC; youth report); the Burn Injury Social Questionnaire (BISQ; parent and youth report); and the Piers-Harris Children’s Self-Concept Scale-2 (PH-2; youth report). Associations between coping, social functioning, …


Nutrient Intake And Dietary Inflammatory Potential In Current And Recovered Anorexia Nervosa, Olivia Patsalos, Bethan Dalton, Christia Kyprianou, Joseph Firth, Nitin Shivappa Mbbs, Mph, Ph.D., James Hébert Scd, Ulrike Schmidt, Hubertus Himmerich Dec 2021

Nutrient Intake And Dietary Inflammatory Potential In Current And Recovered Anorexia Nervosa, Olivia Patsalos, Bethan Dalton, Christia Kyprianou, Joseph Firth, Nitin Shivappa Mbbs, Mph, Ph.D., James Hébert Scd, Ulrike Schmidt, Hubertus Himmerich

Faculty Publications

Anorexia nervosa (AN) is characterised by disrupted and restrictive eating patterns. Recent investigations and meta-analyses have found altered concentrations of inflammatory markers in people with current AN. We aimed to assess nutrient intake in participants with current or recovered AN, as compared to healthy individuals, and explore group differences in dietary inflammatory potential as a possible explanation for the observed alterations in inflammatory markers. We recruited participants with current AN (n = 51), those recovered from AN (n = 23), and healthy controls (n = 49). We used the Food Frequency Questionnaire (FFQ), to calculate a Dietary …


Self-Efficacy: Nurses’ Perceptions Of Caring For Patients Living With Diabetes, Victoria Y. Mccue Dec 2021

Self-Efficacy: Nurses’ Perceptions Of Caring For Patients Living With Diabetes, Victoria Y. Mccue

Nursing & Health Sciences Research Journal

Introduction: Diabetes is an epidemic that affects over 415 million people worldwide. In the United States, the number of people diagnosed with diabetes is projected to triple to over 60 million by 2060. With this surge, the number of hospitalizations across the country has significantly increased. Direct care nurses play a vital role in the management of patients living with diabetes. The purpose of this research study was to explore and describe medical-surgical nurses’ perceptions of self-efficacy related to caring for patients living with diabetes. This study's guiding research question was: What are nurses’ perceptions on the influences that impact …


The Art Of Nurse Mentoring: A Framework Of Support, Diane S. Kramer, Victoria Y. Mccue, Eve Butler, Andrea S. Prentiss, Maria M. Ojeda, Kayce K. Tugg, Vivian Fuentes, Sally Bonet Dec 2021

The Art Of Nurse Mentoring: A Framework Of Support, Diane S. Kramer, Victoria Y. Mccue, Eve Butler, Andrea S. Prentiss, Maria M. Ojeda, Kayce K. Tugg, Vivian Fuentes, Sally Bonet

Nursing & Health Sciences Research Journal

Introduction: Nursing mentoring relationships are vital to the advancement of personal and professional growth in nursing. Mentoring has been identified as an effective method to decrease turnover resulting in retention of experienced nurses. Despite the benefits of a mentoring relationship, barriers exist in creating and cultivating a formal mentoring program in the hospital setting.

Methods: A qualitative descriptive study approach that explored nurses’ perceptions of a mentoring culture within a hospital environment. Open-ended, conversational-style interviewing techniques with a semi-structured interview guide were utilized to gain a full description of nurses’ perceptions of a mentoring culture within a hospital environment.

Results: …


Letter From The Editor: A Peer Reviewed Journal In A Healthcare System: An Innovative Way Of Dissemination, Nohemi Sadule Rios Dec 2021

Letter From The Editor: A Peer Reviewed Journal In A Healthcare System: An Innovative Way Of Dissemination, Nohemi Sadule Rios

Nursing & Health Sciences Research Journal

No abstract provided.


Hospital Survey On Culture Of Transitions In Patient Care At A Community Hospital, Gwen Burley, Victoria Y. Mccue, Dawn Kressly, Ronye Kreiner Dec 2021

Hospital Survey On Culture Of Transitions In Patient Care At A Community Hospital, Gwen Burley, Victoria Y. Mccue, Dawn Kressly, Ronye Kreiner

Nursing & Health Sciences Research Journal

Background: Delays in patient transitions of care are complex and, therefore, a reductionist model of improvement is not likely to produce sustainable results. Exploration of the culture-performance link in the organization has the potential to guide improvement methods aimed at complex, non-linear processes.

Methods: An exploratory, descriptive correlational study was conducted employing the administration of the Hospital Culture of Transitions in Patient Care survey to a cross sectional convenience sample.

Results: Sixty-three participants responded to the survey. In assigning a grade to transitions in the organization, 35% of participants selected a grade of “A” with 33.3% “B”, …


Overcoming Undergraduate Nursing Education Challenges During The Pandemic, Melissa Abreu, Carolina Ferreiro, Danielle Garcia, Gisell Gonzalvo, Erika Nusbaum, Beatrice Sikah Dec 2021

Overcoming Undergraduate Nursing Education Challenges During The Pandemic, Melissa Abreu, Carolina Ferreiro, Danielle Garcia, Gisell Gonzalvo, Erika Nusbaum, Beatrice Sikah

Nursing & Health Sciences Research Journal

Despite the challenges encountered throughout the COVID-19 pandemic, undergraduate nursing education was able to pivot and prevent cessation as faculty and students utilized various virtual platforms to provide didactic, skills lab, and clinical exposure without delaying graduation for many students. Although nothing could replace the hands-on human interaction a clinical rotation provided, virtual experiences aligned with the course content helped students reinforce the concepts taught in the corresponding didactic portion proving this to be beneficial in its own way. As faculty, we rose to the challenge in fostering a supportive environment to keep students motivated to learn and engaged in …


A Performance Improvement Project To Improve Hand-Off Communication Documentation Within The Surgical Services Department, Bobbie J. Wich, Millie Escalona, Judy E. Bowling, Ana L. Santos Dec 2021

A Performance Improvement Project To Improve Hand-Off Communication Documentation Within The Surgical Services Department, Bobbie J. Wich, Millie Escalona, Judy E. Bowling, Ana L. Santos

Nursing & Health Sciences Research Journal

Over 80% of adverse events in healthcare are due to miscommunication. To improve patient safety, The Joint Commission recommended the use of standardized hand-off communication tools in 2012. One acute care hospital in Southeast Florida implemented standardized handoff reports in 2014 with few revisions since that time. The COVID-19 pandemic brought to light additional critical information was needed to keep patients and staff safe, such as laboratory results indicating the need for isolation precautions. The nurses within the surgical services noticed this critical information was not sufficiently included in the handoff report. The lack of this information led to unnecessary …


Could There Be A Good Side To Covid-19 Pandemic?, Donna Shaw, Theressa Brahim, Catherina Chang Martinez Dec 2021

Could There Be A Good Side To Covid-19 Pandemic?, Donna Shaw, Theressa Brahim, Catherina Chang Martinez

Nursing & Health Sciences Research Journal

As the COVID-19 pandemic unfolded, resulting in loss of lives, burnout, anxiety, and depression related to social distancing and quarantine measures, some positive changes have been reported at the individual, interpersonal, and community level. Self-reflection, social connectedness, connectivity, innovation, and resilience have emerged as positive values that have contributed to decrease in burnout during the post-COVID pandemic era.


A Nursing Leader’S Perspective In Preparing For Magnet® Redesignation In The Midst Of The Covid-19 Pandemic, Harold Girado Dec 2021

A Nursing Leader’S Perspective In Preparing For Magnet® Redesignation In The Midst Of The Covid-19 Pandemic, Harold Girado

Nursing & Health Sciences Research Journal

No abstract provided.


Meta-Analyses Identify Dna Methylation Associated With Kidney Function And Damage, Pascal Schlosser, Adrienne Tin, Pamela R Matias-Garcia, Chris H L Thio, Roby Joehanes, Hongbo Liu, Antoine Weihs, Zhi Yu, Anselm Hoppmann, Franziska Grundner-Culemann, Josine L Min, Adebowale A Adeyemo, Charles Agyemang, Johan Ärnlöv, Nasir A Aziz, Andrea Baccarelli, Murielle Bochud, Hermann Brenner, Monique M B Breteler, Cristian Carmeli, Layal Chaker, John C Chambers, Shelley A Cole, Josef Coresh, Tanguy Corre, Adolfo Correa, Simon R Cox, Niek De Klein, Graciela E Delgado, Arce Domingo-Relloso, Kai-Uwe Eckardt, Arif B Ekici, Karlhans Endlich, Kathryn L Evans, James S Floyd, Myriam Fornage, Lude Franke, Eliza Fraszczyk, Xu Gao, Xīn Gào, Mohsen Ghanbari, Sahar Ghasemi, Christian Gieger, Philip Greenland, Megan L Grove, Sarah E Harris, Gibran Hemani, Peter Henneman, Christian Herder, Steve Horvath, Lifang Hou, Mikko A Hurme, Shih-Jen Hwang, Marjo-Riitta Jarvelin, Sharon L R Kardia, Silva Kasela, Marcus E Kleber, Wolfgang Koenig, Jaspal S Kooner, Holly Kramer, Florian Kronenberg, Brigitte Kühnel, Terho Lehtimäki, Lars Lind, Dan Liu, Yongmei Liu, Donald M Lloyd-Jones, Kurt Lohman, Stefan Lorkowski, Ake T Lu, Riccardo E Marioni, Winfried März, Daniel L Mccartney, Karlijn A C Meeks, Lili Milani, Pashupati P Mishra, Matthias Nauck, Ana Navas-Acien, Christoph Nowak, Annette Peters, Holger Prokisch, Bruce M Psaty, Olli T Raitakari, Scott M Ratliff, Alex P Reiner, Sylvia E Rosas, Ben Schöttker, Joel Schwartz, Sanaz Sedaghat, Jennifer A Smith, Nona Sotoodehnia, Hannah R Stocker, Silvia Stringhini, Johan Sundström, Brenton R Swenson, Maria Tellez-Plaza, Joyce B J Van Meurs, Jana V Van Vliet-Ostaptchouk, Andrea Venema, Niek Verweij, Rosie M Walker, Matthias Wielscher, Juliane Winkelmann, Bruce H R Wolffenbuttel, Wei Zhao, Yinan Zheng, Marie Loh, Harold Snieder, Daniel Levy, Melanie Waldenberger, Katalin Susztak, Anna Köttgen, Alexander Teumer Dec 2021

Meta-Analyses Identify Dna Methylation Associated With Kidney Function And Damage, Pascal Schlosser, Adrienne Tin, Pamela R Matias-Garcia, Chris H L Thio, Roby Joehanes, Hongbo Liu, Antoine Weihs, Zhi Yu, Anselm Hoppmann, Franziska Grundner-Culemann, Josine L Min, Adebowale A Adeyemo, Charles Agyemang, Johan Ärnlöv, Nasir A Aziz, Andrea Baccarelli, Murielle Bochud, Hermann Brenner, Monique M B Breteler, Cristian Carmeli, Layal Chaker, John C Chambers, Shelley A Cole, Josef Coresh, Tanguy Corre, Adolfo Correa, Simon R Cox, Niek De Klein, Graciela E Delgado, Arce Domingo-Relloso, Kai-Uwe Eckardt, Arif B Ekici, Karlhans Endlich, Kathryn L Evans, James S Floyd, Myriam Fornage, Lude Franke, Eliza Fraszczyk, Xu Gao, Xīn Gào, Mohsen Ghanbari, Sahar Ghasemi, Christian Gieger, Philip Greenland, Megan L Grove, Sarah E Harris, Gibran Hemani, Peter Henneman, Christian Herder, Steve Horvath, Lifang Hou, Mikko A Hurme, Shih-Jen Hwang, Marjo-Riitta Jarvelin, Sharon L R Kardia, Silva Kasela, Marcus E Kleber, Wolfgang Koenig, Jaspal S Kooner, Holly Kramer, Florian Kronenberg, Brigitte Kühnel, Terho Lehtimäki, Lars Lind, Dan Liu, Yongmei Liu, Donald M Lloyd-Jones, Kurt Lohman, Stefan Lorkowski, Ake T Lu, Riccardo E Marioni, Winfried März, Daniel L Mccartney, Karlijn A C Meeks, Lili Milani, Pashupati P Mishra, Matthias Nauck, Ana Navas-Acien, Christoph Nowak, Annette Peters, Holger Prokisch, Bruce M Psaty, Olli T Raitakari, Scott M Ratliff, Alex P Reiner, Sylvia E Rosas, Ben Schöttker, Joel Schwartz, Sanaz Sedaghat, Jennifer A Smith, Nona Sotoodehnia, Hannah R Stocker, Silvia Stringhini, Johan Sundström, Brenton R Swenson, Maria Tellez-Plaza, Joyce B J Van Meurs, Jana V Van Vliet-Ostaptchouk, Andrea Venema, Niek Verweij, Rosie M Walker, Matthias Wielscher, Juliane Winkelmann, Bruce H R Wolffenbuttel, Wei Zhao, Yinan Zheng, Marie Loh, Harold Snieder, Daniel Levy, Melanie Waldenberger, Katalin Susztak, Anna Köttgen, Alexander Teumer

Faculty, Staff and Student Publications

Chronic kidney disease is a major public health burden. Elevated urinary albumin-to-creatinine ratio is a measure of kidney damage, and used to diagnose and stage chronic kidney disease. to extend the knowledge on regulatory mechanisms related to kidney function and disease, we conducted a blood-based epigenome-wide association study for estimated glomerular filtration rate (n = 33,605) and urinary albumin-to-creatinine ratio (n = 15,068) and detected 69 and seven CpG sites where DNA methylation was associated with the respective trait. The majority of these findings showed directionally consistent associations with the respective clinical outcomes chronic kidney disease and moderately increased albuminuria. …


Epigenome-Wide Association Study Of Serum Urate Reveals Insights Into Urate Co-Regulation And The Slc2a9 Locus, Adrienne Tin, Pascal Schlosser, Pamela R Matias-Garcia, Chris H L Thio, Roby Joehanes, Hongbo Liu, Zhi Yu, Antoine Weihs, Anselm Hoppmann, Franziska Grundner-Culemann, Josine L Min, Victoria L Halperin Kuhns, Adebowale A Adeyemo, Charles Agyemang, Johan Ärnlöv, Nasir A Aziz, Andrea Baccarelli, Murielle Bochud, Hermann Brenner, Jan Bressler, Monique M B Breteler, Cristian Carmeli, Layal Chaker, Josef Coresh, Tanguy Corre, Adolfo Correa, Simon R Cox, Graciela E Delgado, Kai-Uwe Eckardt, Arif B Ekici, Karlhans Endlich, James S Floyd, Eliza Fraszczyk, Xu Gao, Xīn Gào, Allan C Gelber, Mohsen Ghanbari, Sahar Ghasemi, Christian Gieger, Philip Greenland, Megan L Grove, Sarah E Harris, Gibran Hemani, Peter Henneman, Christian Herder, Steve Horvath, Lifang Hou, Mikko A Hurme, Shih-Jen Hwang, Sharon L R Kardia, Silva Kasela, Marcus E Kleber, Wolfgang Koenig, Jaspal S Kooner, Florian Kronenberg, Brigitte Kühnel, Christine Ladd-Acosta, Terho Lehtimäki, Lars Lind, Dan Liu, Donald M Lloyd-Jones, Stefan Lorkowski, Ake T Lu, Riccardo E Marioni, Winfried März, Daniel L Mccartney, Karlijn A C Meeks, Lili Milani, Pashupati P Mishra, Matthias Nauck, Christoph Nowak, Annette Peters, Holger Prokisch, Bruce M Psaty, Olli T Raitakari, Scott M Ratliff, Alex P Reiner, Ben Schöttker, Joel Schwartz, Sanaz Sedaghat, Jennifer A Smith, Nona Sotoodehnia, Hannah R Stocker, Silvia Stringhini, Johan Sundström, Brenton R Swenson, Joyce B J Van Meurs, Jana V Van Vliet-Ostaptchouk, Andrea Venema, Uwe Völker, Juliane Winkelmann, Bruce H R Wolffenbuttel, Wei Zhao, Yinan Zheng, Marie Loh, Harold Snieder, Melanie Waldenberger, Daniel Levy, Shreeram Akilesh, Owen M Woodward, Katalin Susztak, Alexander Teumer, Anna Köttgen Dec 2021

Epigenome-Wide Association Study Of Serum Urate Reveals Insights Into Urate Co-Regulation And The Slc2a9 Locus, Adrienne Tin, Pascal Schlosser, Pamela R Matias-Garcia, Chris H L Thio, Roby Joehanes, Hongbo Liu, Zhi Yu, Antoine Weihs, Anselm Hoppmann, Franziska Grundner-Culemann, Josine L Min, Victoria L Halperin Kuhns, Adebowale A Adeyemo, Charles Agyemang, Johan Ärnlöv, Nasir A Aziz, Andrea Baccarelli, Murielle Bochud, Hermann Brenner, Jan Bressler, Monique M B Breteler, Cristian Carmeli, Layal Chaker, Josef Coresh, Tanguy Corre, Adolfo Correa, Simon R Cox, Graciela E Delgado, Kai-Uwe Eckardt, Arif B Ekici, Karlhans Endlich, James S Floyd, Eliza Fraszczyk, Xu Gao, Xīn Gào, Allan C Gelber, Mohsen Ghanbari, Sahar Ghasemi, Christian Gieger, Philip Greenland, Megan L Grove, Sarah E Harris, Gibran Hemani, Peter Henneman, Christian Herder, Steve Horvath, Lifang Hou, Mikko A Hurme, Shih-Jen Hwang, Sharon L R Kardia, Silva Kasela, Marcus E Kleber, Wolfgang Koenig, Jaspal S Kooner, Florian Kronenberg, Brigitte Kühnel, Christine Ladd-Acosta, Terho Lehtimäki, Lars Lind, Dan Liu, Donald M Lloyd-Jones, Stefan Lorkowski, Ake T Lu, Riccardo E Marioni, Winfried März, Daniel L Mccartney, Karlijn A C Meeks, Lili Milani, Pashupati P Mishra, Matthias Nauck, Christoph Nowak, Annette Peters, Holger Prokisch, Bruce M Psaty, Olli T Raitakari, Scott M Ratliff, Alex P Reiner, Ben Schöttker, Joel Schwartz, Sanaz Sedaghat, Jennifer A Smith, Nona Sotoodehnia, Hannah R Stocker, Silvia Stringhini, Johan Sundström, Brenton R Swenson, Joyce B J Van Meurs, Jana V Van Vliet-Ostaptchouk, Andrea Venema, Uwe Völker, Juliane Winkelmann, Bruce H R Wolffenbuttel, Wei Zhao, Yinan Zheng, Marie Loh, Harold Snieder, Melanie Waldenberger, Daniel Levy, Shreeram Akilesh, Owen M Woodward, Katalin Susztak, Alexander Teumer, Anna Köttgen

Faculty, Staff and Student Publications

Elevated serum urate levels, a complex trait and major risk factor for incident gout, are correlated with cardiometabolic traits via incompletely understood mechanisms. DNA methylation in whole blood captures genetic and environmental influences and is assessed in transethnic meta-analysis of epigenome-wide association studies (EWAS) of serum urate (discovery, n = 12,474, replication, n = 5522). The 100 replicated, epigenome-wide significant (p < 1.1E-7) CpGs explain 11.6% of the serum urate variance. At SLC2A9, the serum urate locus with the largest effect in genome-wide association studies (GWAS), five CpGs are associated with SLC2A9 gene expression. Four CpGs at SLC2A9 have significant causal effects on serum urate levels and/or gout, and two of these partly mediate the effects of urate-associated GWAS variants. In other genes, including SLC7A11 and PHGDH, 17 urate-associated CpGs are associated with conditions defining metabolic syndrome, suggesting that these CpGs may represent a blood DNA methylation signature of cardiometabolic risk factors. This study demonstrates that EWAS can provide new insights into GWAS loci and the correlation of serum urate with other complex traits.


Letter To The Editor From Baptist Health South Florida Chief Well-Being Officer, Ana Viamonte Ros Dec 2021

Letter To The Editor From Baptist Health South Florida Chief Well-Being Officer, Ana Viamonte Ros

Nursing & Health Sciences Research Journal

No abstract provided.


Barriers Of Bronson School Of Nursing Program, Karla Kline Dec 2021

Barriers Of Bronson School Of Nursing Program, Karla Kline

Honors Theses

Aside from the rigorous coursework of nursing school, nursing students experience various barriers that impact their academic success. Barriers to successful completion of traditional Bachelor of Science of Nursing (BSN) programs include isolation, lack of peer connections, lack of faculty connections, lack of family support, lack of financial support, and mental health struggles (Shaw, 2015) (Seal & Woods, 2021). This research will aim at assessing and exploring these barriers students are facing, along with the additional or exacerbated barriers the COVID-19 pandemic has surfaced.

This study will expand on the research conducted by Shaw (2015), in which she examined the …


Generating Evidence From Contextual Clinical Research In Low- To Middle Income Countries: A Roadmap Based On Theory Of Change, Babar Hasan, Muneera Rasheed, Asra Wahid, Raman Krishna Kumar, Liesl Zuhlke Dec 2021

Generating Evidence From Contextual Clinical Research In Low- To Middle Income Countries: A Roadmap Based On Theory Of Change, Babar Hasan, Muneera Rasheed, Asra Wahid, Raman Krishna Kumar, Liesl Zuhlke

Department of Paediatrics and Child Health

Along with inadequate access to high-quality care, competing health priorities, fragile health systems, and conflicts, there is an associated delay in evidence generation and research from LMICs. Lack of basic epidemiologic understanding of the disease burden in these regions poses a significant knowledge gap as solutions can only be developed and sustained if the scope of the problem is accurately defined. Congenital heart disease (CHD), for example, is the most common birth defect in children. The prevalence of CHD from 1990 to 2017 has progressively increased by 18.7% and more than 90% of children with CHD are born in Low …


Distressed Personality Among Yemeni Patients With Coronary Artery Disease: An Exploratory Study, Faida Ahmed Obeid, Amal Saddik Ba - Saddik Dec 2021

Distressed Personality Among Yemeni Patients With Coronary Artery Disease: An Exploratory Study, Faida Ahmed Obeid, Amal Saddik Ba - Saddik

Hadhramout University Journal of Natural & Applied Sciences

Coronary artery disease (CAD) is the main health problem in the world with high mortality and disability, distressed personality (type D personality) was developed as an emerging psychological risk factor in CAD. This study aimed to explore the prevalence of distressed personality among patients with CAD and to investigate the association between the demographic and clinical characteristic of Type D and non-Type D personality in a sample of 74 CAD Yemeni patients who presented to Algamhouria Teaching Hospital and a private clinic in Aden between April 2017 and May 2018 diagnosed by consultant cardiologist. The Type D Scale-14 (DS14) and …


Case Report Silver-Russell Syndrome: A Case Report Of Three Years Old Yemeni Boy, Mazin Ahmed Jawass, Hanan Saeed Bin Gouth Dec 2021

Case Report Silver-Russell Syndrome: A Case Report Of Three Years Old Yemeni Boy, Mazin Ahmed Jawass, Hanan Saeed Bin Gouth

Hadhramout University Journal of Natural & Applied Sciences

Silver Russell Syndrome (SRS) is a rare condition. For diagnosis of SRS at least four of the following criteria should be present which are intrauterine growth retardation , postnatal growth retardation , preservation of occipitofrontal head circumference, classic facial phenotype (broad prominent forehead with small triangular face, small narrow chin and low set ears) and body asymmetry. There is no data about cases of SRS reported in Yemen. We present a three years old Yemeni boy with SRS. He is the first child of Yemeni consanguineous parent‟s average length. He is born following normal pregnancy. The boy fulfilled the criteria …


Cutaneous Hyperpigmentation: A Rare Extra-Intestinal Manifestation Of Celiac Disease, Noor Abdulaziz Binkroom, Omar Abdul-Rahman Bawazir, Faiza Salmeen Naji Dec 2021

Cutaneous Hyperpigmentation: A Rare Extra-Intestinal Manifestation Of Celiac Disease, Noor Abdulaziz Binkroom, Omar Abdul-Rahman Bawazir, Faiza Salmeen Naji

Hadhramout University Journal of Natural & Applied Sciences

Celiac disease has many manifestations. In paediatric population, it is usually presented as malabsorption with chronic diarrhea and poor growth. This female child of 3.5 year old from Shabwa governorate was presented to us with anemia required frequent blood transfusions and black discoloration of skin particularly of hands and feet. There was no gastrointestinal symptoms. Her growth parameters and rest of clinical picture was normal apart from paleness and skin black discoloration. Her initial investigations showed low Hb, normal WBC and Plat count, blood film showed leukoerthoblastic picture with increased number of atypical lymphocyte, and Bone Marrow Aspiration was inconclusive, …


Changes In Intraocular Pressure After Hemodialysis At Hemodialysis Center Al Gamhoria Teaching Hospital, Aden, Sawsan Fuad Mohamed, Abeer Ahmed Ba Abbad, Seena Abdulla Yousuf Dec 2021

Changes In Intraocular Pressure After Hemodialysis At Hemodialysis Center Al Gamhoria Teaching Hospital, Aden, Sawsan Fuad Mohamed, Abeer Ahmed Ba Abbad, Seena Abdulla Yousuf

Hadhramout University Journal of Natural & Applied Sciences

The relationship between intraocular pressure (IOP) changes and haemodialysis (HD) has been evaluated for more than 50 years, the reported findings are variable.The aim of the study is to evaluate the changes in IOP after HD.Ninety patients (180 eyes) undergoing HD with chronic renal failure were enrolled. Measurement of IOP was taken before and approximately 5 minutes after ending HD . Demographic data, causes of the chronic renal failure, duration of HD, and medical history of eye state were recorded. The mean age of the patients was 40.8 ± 14.1 years. The mean pre-dialysis IOP was 14.538 ± 3.66 mm …


Mortality And Morbidity Among Preterm Neonates Admitted To Al-Mukalla Maternity And Childhood Hospital, Yemen, Hanan Saeed Bin Gouth, Saleh Awad Bahwel, Mazin Ahmed Jawass, Ali Salim Bahartha, Fauzia Faraj Bamatraf Dec 2021

Mortality And Morbidity Among Preterm Neonates Admitted To Al-Mukalla Maternity And Childhood Hospital, Yemen, Hanan Saeed Bin Gouth, Saleh Awad Bahwel, Mazin Ahmed Jawass, Ali Salim Bahartha, Fauzia Faraj Bamatraf

Hadhramout University Journal of Natural & Applied Sciences

Globally, preterm birth is a major clinical problem associated with significant mortality and morbidity in the perinatal, neonatal, and childhood periods and even in adulthood. The study aimed to evaluate the mortality and morbidity of preterm neonates admitted to Maternity and Childhood Hospital (MCH) in Al-Mukalla. A retrospective case-control study at a ratio of 1 1 was conducted in the neonatal unit of pediatric ward from October 2012 to October 2013. The study included records of 104 preterm neonates as cases and equal numbers of full term neonates as control. The results showed high mortality rate (22.6%) among the neonates. …


Prevalence And Seasonality Of Acute Appendicitis Among Patients Registered At Ibn- Sina General Hospital In Al-Mukalla, Yemen, Abdulla Saleh Alyamani, Fauzia Faraj Bamatraf Dec 2021

Prevalence And Seasonality Of Acute Appendicitis Among Patients Registered At Ibn- Sina General Hospital In Al-Mukalla, Yemen, Abdulla Saleh Alyamani, Fauzia Faraj Bamatraf

Hadhramout University Journal of Natural & Applied Sciences

Appendicitis is the most common acute surgical condition of the abdomen. Age, sex and seasonal variations have been observed in many studies. The aim of the study is to determine the prevalence and seasonality of acute appendicitis among patients registered in Ibn-Sina general hospital (ISGH) in Al-Mukalla. In this retrospective study. The data was collected from admission records in surgical department of ISGH during the period January 2011 - December 2017. Out of 12580 patients attending surgical ward, 2565 patients with acute appendicitis were collected from records of the hospital. The prevalence of acute appendicitis during the study years was …


Prevalence Of Metabolic Syndrome Among Hypertensive Patients In Hadhramout, Republic Of Yemen, Rasheed Mohammed Bamekhlah, Hussain Saeed Alghazali Dec 2021

Prevalence Of Metabolic Syndrome Among Hypertensive Patients In Hadhramout, Republic Of Yemen, Rasheed Mohammed Bamekhlah, Hussain Saeed Alghazali

Hadhramout University Journal of Natural & Applied Sciences

The aim of this study was to determine the prevalence of metabolic syndrome among hypertensive patients. A crosssectional study conducted at Al-Rayan Specialized Hospital, Mukalla, Hadramout during (2/2015 - 4/2016). From 345 patients, 207 were diagnosed as metabolic syndrome (60%), with mean age (57.9±9.2) years was significantly higher than that of patients without the syndrome (44.7±6.6) years (p ˂0.0001). Females with the syndrome were significantly higher than males (67.6% and 32.4% respectively) compared with patients without, (p ˂0.0001). As Hypertension was present in all studied patients, diabetes was the commonest metabolic syndrome component in patients with the syndrome (79.2%), followed …


Case Report Intramedullary Epidermoid Cyst: A Rare Intraspinal Tumor, Abdulkhaleq Ayedh Bin Nuhaid, Wadea Saeed Bin Ghouth Dec 2021

Case Report Intramedullary Epidermoid Cyst: A Rare Intraspinal Tumor, Abdulkhaleq Ayedh Bin Nuhaid, Wadea Saeed Bin Ghouth

Hadhramout University Journal of Natural & Applied Sciences

We adduce this case of a very rare intraspinal tumor, an intramedullary epidermoid cyst in a male child of a 3 yearold, which is also a rare age presentation. This tumor was diagnosed through spine magnetic resonance imaging(MRI) examination. The child presented with spastic paraparesis of about three months’ duration. The child was set for spine computed tomographic(CT) scan examination (prior to the MRI study) that failed to detect the lesion well, leading to delay of correct management. MRI should be carried out directly as the investigation of first choice whenever spinal lesion questionable in non-informative CT scan study. In …


Color Doppler Ultrasonographic Evaluation Of Varicocele: Best Position And Site For Improving Maximal Vein Diameter Measurement, Jamal Omer Bahabara, Wadea Saeed Bin Ghouth Dec 2021

Color Doppler Ultrasonographic Evaluation Of Varicocele: Best Position And Site For Improving Maximal Vein Diameter Measurement, Jamal Omer Bahabara, Wadea Saeed Bin Ghouth

Hadhramout University Journal of Natural & Applied Sciences

The purpose of this study is to identify the best position and site for color Doppler ultrasonography evaluation of testicular vein to obtain optimal diameter measurement. Over the first six months of the year 2017, eighty nine patients aged 22-48 years who proved to have varicocele were included in the study. Color Doppler sonography was performed using a 7.5 MHz linear-array transducer, and the diameter of the largest testicular vein at three different sites was measured in both supine and standing positions with and without Valsalva maneuver. Patients' varicoceles were graded according to the supine-rest maximum vein diameter into: Grade …


Fatal Dengue Cases In Mukalla - Hadhramout : Causes And Alarming Signals, Abdulrahim Abdulla Bahashwan, Ahmed Mubarak Daakeek, Husain Saeed Alghasali Dec 2021

Fatal Dengue Cases In Mukalla - Hadhramout : Causes And Alarming Signals, Abdulrahim Abdulla Bahashwan, Ahmed Mubarak Daakeek, Husain Saeed Alghasali

Hadhramout University Journal of Natural & Applied Sciences

A prospective descriptive study was conducted in Ib-Sina Hospital- Mukalla-Hadhramout To identify the causes and alarming signal of dengue -related deaths during the 2015-2016 dengue outbreak in Mukalla –Hadhramout- Yemen. Deaths due to dengue fever were reviewed from hospital records. Demographic details, clinical features, laboratory findings, and the treatment charts of death cases were reviewed and documented. Comorbidities were also listed, and causes and warning signs were evaluated and highlighted. Out of 424 dengue fever patients who admitted during outbreak period, 18 dengue-related deaths were reported (4.25%); 10 (55.6%) were male, and 8 (44.4%) were female. The median age was …


Causes Of Mortality In Children 1-59 Months In Yemen, Fauzia Faraj Bamatraf, Noor Abdul-Aziz Binkroom, Mazin Ahmed Jawass Dec 2021

Causes Of Mortality In Children 1-59 Months In Yemen, Fauzia Faraj Bamatraf, Noor Abdul-Aziz Binkroom, Mazin Ahmed Jawass

Hadhramout University Journal of Natural & Applied Sciences

Child mortality is a sensitive indicator of a country’s development and telling evidence of its priorities and values. The study aimed to determine the common causes of death among children under 5 years of age who admitted and died in Al-Mukalla public hospitals , Yemen. This was a retrospective study. The files of all children aged 1-59 months who admitted into the pediatric wards at Mukalla City Hospital and University Hospital for Gynecology , Obstetric and pediatric and died during the study period from the 1st of January 2011 to the 31st of December 2014 were reviewed. Out of 5859 …


Recurrent Pneumonia In Children Attending Mukalla City Hospital –Yemen, Saleh Awad Bahwal, Mazin Ahmed Jawass, Hanan Saeed Bin Gouth Dec 2021

Recurrent Pneumonia In Children Attending Mukalla City Hospital –Yemen, Saleh Awad Bahwal, Mazin Ahmed Jawass, Hanan Saeed Bin Gouth

Hadhramout University Journal of Natural & Applied Sciences

Recurrent pneumonia in children continues to be a major problem for the pediatricians. The aim of our study was to determine the prevalence and predisposing causes of recurrent pneumonia (RP) in children. This is a prospective hospital-based study. Children between 2 months and 15 years old who had a history of pneumonia were investigated in order to determine the prevalence and predisposing causes of recurrent pneumonia in children at Mukalla city hospital, Mukalla,Yemen in between January 2014 and December 2016.The result revealed that out of 920 children hospitalized for pneumonia, 80 (8.7%) met the study criteria for RP. Their age …


Benign Paroxysmal Positional Vertigo: Effectiveness Of Canal Repositioning Procedure, Saleh Mohamed Alshaiby Dec 2021

Benign Paroxysmal Positional Vertigo: Effectiveness Of Canal Repositioning Procedure, Saleh Mohamed Alshaiby

Hadhramout University Journal of Natural & Applied Sciences

The objectives of this study were to describe the frequency of benign paroxysmal positional vertigo (BPPV), to assess the effectiveness of canal repositioning procedure & its recurrence and to find out the relationship of with osteoporosis and menopause. This was a retrospective study of all patients with BPPV seen in ENT private clinic in Aden over six-years period. The total patients were 400 patients. They were 87 (21.7%) males and 313 (78.3%) females with ratio male to female 1:3.6. The mean age of patients was (53.79±7.25) years. Most common effected ear was the right ear with (70.7%). The effected right …