Medicine and Health Sciences Commons^™

Trajectories Of Covid-19 Vaccine Intentions Among Us Adults: The Role Of Race And Ethnicity, Michael D. Niño, Brittany N. Hearne, Tianji Cai

Sociology and Criminology Faculty Publications and Presentations

Research examining whether intentions to get a COVID-19 vaccine change over time is scarce. Moreover, the deep and pervasive history of medical racism in the U.S. has created a context in which some racial and ethnic groups exhibit greater levels of COVID-19 vaccine hesitancy; yet few researchers have attempted to determine whether these patterns persist with time. The purpose of this study was twofold: (a.) assess the role of time in COVID-19 vaccine intentions from April 2020 to January 2021, and (b.) examine whether race and ethnicity shape COVID-19 vaccine intention trajectories. Data were drawn from 9 waves of the …

2021-09-01_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …

Law Helps Ensure Safety Of The Supply Chain, Kenneth Maxik, Craig Kimble, Alberto Coustasse

Management Faculty Research

The Drug Quality and Security Act was signed into law on November 27, 2013, and included the Title 2 Drug Supply Chain and Security Act (DSCSA). This legislation was introduced to enact a federal prescription drug safety standard to decrease contamination, counterfeiting, diversion, and otherwise harmful illicit activities. It also improves the detection and elimination of potentially unsafe drugs from the drug supply chain to protect US consumers.

Facilitating Well-Rounded Clinical Experience For Psychiatric Nurse Practitioner Students, Joan Alviar Fraino, Nancy Selix

Nursing and Health Professions Faculty Research and Publications

There is a steady increase in demand for mental health services and a lack of providers. Recent societal changes resulting from the COVID-19 pandemic have increased these needs. Psychiatric mental health nurse practitioners (PMHNP) are well suited to offer these services. High-quality clinical PMHNP student experiences are based on well-rounded curricula in a variety of clinical settings. Meeting the need for clinical education and finding high-quality preceptors is especially challenging during the pandemic due to the lack of preceptors and access to care for in-person services. Creative approaches are needed to meet student clinical experience needs.

Direct-Acting Oral Anticoagulants Versus Warfarin In Relation To Risk Of Gastrointestinal Bleeding: A Systematic Review And Meta-Analysis Of Randomized Controlled Trials., Mark M Aloysius, Abhilash Perisetti Md, Hemant Goyal, Umesha Boregowda, Mladen Jecmenica, Mahesh Cheryala, Anurag Bajaj, Bojana Milekic, Milos Babic, Pardeep Bansal, Greg H Enders

Other Specialties

Background: Direct-acting oral anticoagulants (DOACs) are increasingly used, with studies showing a lower risk of gastrointestinal bleeding (GIB), but overall data for GIB risk remains debatable. The objective was to assess non-fatal and fatal GIB risk in patients on DOACs compared with warfarin from randomized clinical trials (RCTs).

Methods: RCTs comparing warfarin and DOACs for various indications (atrial fibrillation, thromboembolism, insertion of mechanical heart valves) were included. The primary endpoint was any GIB event. Other clinical events, such as fatal GIB, and effects of age (≤60 years or older), time in therapeutic range for warfarin, and choice of individual DOACs …

Development And Validation Of A Model To Predict Posttraumatic Stress Disorder And Major Depression After A Motor Vehicle Collision, Steven Bruce, Hannah Ziobrowski, Chris Kennedy, Berk Ustun, Stacey House, Francesca Beaudoin, Xinming An, Donglin Zeng, Kenneth Bollen, Maria Petukhova, Nancy Sampson, Victor Puac-Polanco, Sue Lee, Karestan Koenen, Kerry Ressler, Samuel Mclean, Ronald Kessler, Aurora Consortium

Psychology Faculty Works

Importance A substantial proportion of the 40 million people in the US who present to emergency departments (EDs) each year after traumatic events develop posttraumatic stress disorder (PTSD) or major depressive episode (MDE). Accurately identifying patients at high risk in the ED would facilitate the targeting of preventive interventions.Objectives To develop and validate a prediction tool based on ED reports after a motor vehicle collision to predict PTSD or MDE 3 months later.Design, Setting, and Participants The Advancing Understanding of Recovery After Trauma (AURORA) study is a longitudinal study that examined adverse posttraumatic neuropsychiatric sequalae among patients who presented to …

Meditation-Induced After Death Communication: A Contemporary Modality For Grief Therapy, Neda Wassie

International Journal of Transpersonal Studies

Meditation-induced after death communication (MI-ADC) was introduced as a potential modality for grief therapy. Traditional and contemporary approaches were compared in order to evaluate effective paradigms and theories of bereavement. The Continuing Bonds theory of attachment emerged as an adaptive framework for grief therapy, especially with attention to meaning-making and the strength of continued bonds. Considerations were implemented from research in psychomanteum, mediumship, and induced after death communication. Specifically, visual stimuli and timing of after death communications were emphasized. The discussion was encouraging for the conceptualization of MI-ADC as an effective construct and as an inquiry for empirical research.

Locating The Embodied Sense Of Self And Examining Its Relationship With Psychological Well-Being, Adam Wesley Hanley, Natalie Lecy, Robert Hanley

International Journal of Transpersonal Studies

Westerners tend to localize their sense of self in the head, and, to a lesser degree, in the chest. However, single-point, localization studies of the self omit direct exploration of the size and shape of the embodied self. This study explored a) beliefs about the location and spatial distribution of the embodied sense of self, and b) whether individual differences in how the embodied self was represented were associated with psychological and subjective well-being. Results from a sample of 206 American adults confirm extant reports, indicating that the embodied sense of self is most often located in the head and …

Gastric Sleeve Eras - Ketorolac In Gastric Bypass Patients And Risk Of Bleeding, Children's Mercy Kansas City

Clinical Critically Appraised Topics

No abstract provided.

Exercise-Induced Oxidative Stress And Melatonin Supplementation: Current Evidence, Joanna Kruk, Basil Hassan Aboul-Enein, Ewa Duchnik

Health & Wellness Department Faculty Publications and Research

Melatonin possesses the indoleamine structure and exerts antioxidant and anti-inflammatory actions and other physiological properties. Physical exercise can influence secretion of melatonin. Melatonin is used as a natural supplement among athletes to regulate sleep cycles and protect muscles against oxidative damage. Despite decades of research, there is still a lack of a comprehensive and critical review on melatonin supplementation and physical activity relationship. The aim of this literature review is to examine the antioxidant, anti-inflammatory and other biological functions played by melatonin with reference to the effect of physical exercise on melatonin secretion and the effect of this compound supplementation …

Table Of Contents—Masthead

International Journal of Transpersonal Studies

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Harris Friedman: Pioneer Of Transpersonal Psychology As A Science, Harris L. Friedman, Glenn Hartelius

International Journal of Transpersonal Studies

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Intimations Of A Spiritual New Age: V. Socio-Cultural Bases Of A Globalizing Neo-Shamanism And Its Relation To Climate Crisis: Possibilities, Inevitabilities, Barriers, Harry T. Hunt

International Journal of Transpersonal Studies

Extending this series of papers on a futural spirituality, and considering the numinous as an inherent human capacity for an awe that confers a sense of all-inclusive meaning, communality, and humility, the question arises whether, in the face of a secularization of traditional world religions, globalization of a techno/capitalist economy of perpetual commodification of planet and person, and a widening sense of loss of meaning and higher purpose, some collective re-newal of the sense of the sacred might be possible —or not. While Jung, Toynbee, and Sorokin regarded such a movement as inevitable, bringing forward to the degree possible the …

Brain Activity During Paired And Individual Mindfulness Meditation: A Controlled Eeg Study, Hessel Engelbregt, Hugo F. Alderse Bass, Sietske De Grauw, Jan Berend Deijen

International Journal of Transpersonal Studies

Objective: In this study, we evaluated brain electroencephalographic (EEG) activity in healthy participants during the performance of paired and individual mindfulness meditation (MM). We hypothesized that EEG activity is differentially affected by meditation in pairs compared to individual meditation. Methods: A total of 20 healthy female university students (mean age 19.54 years, SD =1.53) with no prior experience in MM participated in this study. All participants had to perform a 5-minute MM task together and individually while the other participant was in rest or performing a concentration task (control condition). To exclude social interaction as main factor, participants were separated …

The Varieties Of Spiritual States Triggered By Sex: A Systematic Review Of The Empirical Literature, Jenny Wade

International Journal of Transpersonal Studies

This systematic review integrates the empirical evidence of spiritual experiences triggered by sexual activity, including studies by 10 authors. Despite venerable sexual meditative traditions of embodied spiritual practices, such as Hindu Tantra, Vajrayana Buddhism, and Taoism, empirical studies of sexual spiritual experiences are in their infancy. This review presents the range of sexual altered states experiences identified to date and how they qualify as spiritual experiences phenomenologically and in terms of their lifechanging effects. Seventeen distinct sexual-spiritual states have been identified across authors, with 4 others identified at significant levels in qualitative studies by individual authors. As an emergent area …

Can Learning Be Enhanced With Active Seating?, Judy Beard, Kirk Mathias

All Faculty Scholarship for the College of Education and Professional Studies

Overweightness continues to increase at an exponential rate in children. This coupled with the demand to increase academic time in elementary schools has contributed to efforts to discover solutions that meet both challenges. Potential solutions are movement curricula and active seating options. However, little has been published relative to best practices of their implementation. Therefore, the purpose of this paper is to discuss the lessons learned while utilizing pedal desks in first and second grade classrooms as stations and whole class seating. Additionally, two different types of heart rate monitors (Polar Oh1 and IHT Spirit) were employed, in an attempt …

Pulmonary Embolism, Intermediate/High Risk, Children's Mercy Kansas City

Clinical Pathways (Formally Known As Care Process Models)

No abstract provided.

A Newly Identified Impairment In Both Vision And Hearing Increases The Risk Of Deterioration In Both Communication And Cognitive Performance, Dawn M. Guthrie, Nicole Williams, Jennifer Campos, Paul Mick, Joseph B. Orange, M. Kathleen Pichora-Fuller, Marie Y. Savundranayagam, Walter Wittich, Natalie A. Phillips

Health Sciences Faculty Publications

Vision and hearing impairments are highly prevalent in adults 65 years of age and older. There is a need to understand their association with multiple health-related outcomes. We analyzed data from the Resident Assessment Instrument for Home Care (RAI-HC). Home care clients were followed for up to 5 years and categorized into seven unique cohorts based on whether or not they developed new vision and/or hearing impairments. An absolute standardized difference (stdiff) of at least 0.2 was considered statistically meaningful. Most clients (at least 60%) were female and 34.9 per cent developed a new sensory impairment. Those with a new …

Drug Susceptibility Of Plasmodium Falciparum In Eastern Uganda: A Longitudinal Phenotypic And Genotypic Study, Patrick K. Tumwebaze, Thomas Katairo, Martin Okitwi, Oswald Byaruhanga, Stephen Orena, Victor Asua, Marvin Duvalsaint, Jennifer Legac, Sevil Chelebieva, Frida G. Ceja, Stephanie A. Rasmussen, Melissa D. Conrad, Samuel L. Nsobya, Ozkan Aydemir, Jeffrey A. Bailey, Brett R. Bayles, Philip J. Rosenthal, Roland A. Cooper

Natural Sciences and Mathematics | Faculty Scholarship

Background: Treatment and control of malaria depends on artemisinin-based combination therapies (ACTs) and is challenged by drug resistance, but thus far resistance to artemisinins and partner drugs has primarily occurred in southeast Asia. The aim of this study was to characterise antimalarial drug susceptibility of Plasmodium falciparum isolates from Tororo and Busia districts in Uganda.

Methods: In this prospective longitudinal study, P falciparum isolates were collected from patients aged 6 months or older presenting at the Tororo District Hospital (Tororo district, a site with relatively low malaria incidence) or Masafu General Hospital (Busia district, a high-incidence site) in eastern Uganda …

The Good Food For Learning Universal Curriculum-Integrated Healthy School Lunch Intervention: Protocol For A Two-Year Matched Control Pre-Post And Case Study, Rachel Engler-Stringer, Jennifer Black, Nazeem Muhajarine, Wanda Martin, Jason Gilliland, Janet Mcvittie, Sara Kirk, Hannah Wittman, Amin Mousavi, Sinikka Elliott, Brent Hills, Gordon Androsoff, Debbie Field, Brit Macdonald, Chelsea Belt, Hassan Vatanparast

Paediatrics Publications

Background: Good nutrition affects children's health, well-being, and learning, and schools offer an important setting to promote healthy behaviors that can last a lifetime. Once children reach school age, they spend more of their waking hours in school than in any other environment. Children's eating habits may be easier to influence than those of adults. In Canada, households with children are more likely to experience food insecurity, and school food programs that are universally available to all children can support the development of healthy eating patterns across groups of varying socioeconomic status. There is a significant gap in the rigorous …

Rates And Determinants Of Mother's Own Milk Feeding In Infants Born Very Preterm, Dinesh Dharel, Nalini Singhal, Christel Wood, Zenon Cieslak, Fabiana Bacchini, Prakesh S. Shah, Xiang Y. Ye, Belal Alshaikh

Paediatrics Publications

Objectives: To examine rates and determinants of mother's own milk (MOM) feeding at hospital discharge in a cohort of infants born very preterm within the Canadian Neonatal Network (CNN). Study design: This was a population-based cohort study of infants born at (NICUs) participating in the CNN between January 1, 2015, and December 31, 2018. We examined the rates and determinants of MOM use at discharge home among the participating NICUs. We used multivariable logistic regression analysis to identify independent determinants of MOM feeding. Results: Among the 6404 infants born very preterm and discharged home during the study period, 4457 (70%) …

The Conundrum Of Low Covid-19 Mortality Burden In Sub-Saharan Africa: Myth Or Reality?, Janica Adams, Mary J. Mackenzie, Adeladza Kofi Amegah, Alex Ezeh, Muktar A. Gadanya, Akinyinka Omigbodun, Ahmed M. Sarki, Paul Thistle, Abdhalah K. Ziraba, Saverio Stranges, Michael Silverman

Global Health Equity Publications

Key Messages

• Evidence suggests the demographic age structure of sub-Saharan Africa is the leading factor of the low morbidity and mortality of COVID-19 compared to other regions of the world.

• Widespread social mitigation strategies, such as lockdowns, have resulted in severe economic and societal consequences in terms of food security, adolescent pregnancy, gender-based violence, and disruptions in treating other diseases.

• It is imperative to weigh the risks and benefits of social mitigation strategies for future waves.

Continuing To Enhance The Quality Of Case Study Methodology In Health Services Research., Shannon L Sibbald, Stefan Paciocco, Meghan Fournie, Rachelle Van Asseldonk, Tiffany Scurr

Health Studies Publications

Case study methodology has grown in popularity within Health Services Research (HSR). However, its use and merit as a methodology are frequently criticized due to its flexible approach and inconsistent application. Nevertheless, case study methodology is well suited to HSR because it can track and examine complex relationships, contexts, and systems as they evolve. Applied appropriately, it can help generate information on how multiple forms of knowledge come together to inform decision-making within healthcare contexts. In this article, we aim to demystify case study methodology by outlining its philosophical underpinnings and three foundational approaches. We provide literature-based guidance to decision-makers, …

Sustained Neural Activity Correlates With Rapid Perceptual Learning Of Auditory Patterns, Björn Herrmann, Kurdo Araz, Ingrid S. Johnsrude

Brain and Mind Institute Researchers' Publications

Repeating structures forming regular patterns are common in sounds. Learning such patterns may enable accurate perceptual organization. In five experiments, we investigated the behavioral and neural signatures of rapid perceptual learning of regular sound patterns. We show that recurring (compared to novel) patterns are detected more quickly and increase sensitivity to pattern deviations and to the temporal order of pattern onset relative to a visual stimulus. Sustained neural activity reflected perceptual learning in two ways. Firstly, sustained activity increased earlier for recurring than novel patterns when participants attended to sounds, but not when they ignored them; this earlier increase mirrored …

Addressing Distress Management Challenges: Recommendations From The Consensus Panel Of The American Psychosocial Oncology Society And The Association Of Oncology Social Work, Teresa L. Deshields, Sharla Wells-Di Gregorio, Stacy R. Flowers, Kelly E. Irwin, Ryan Nipp, Lynne Padgett, Brad Zebrack

Family Medicine Faculty Publications

Distress management (DM) (screening and response) is an essential component of cancer care across the treatment trajectory. Effective DM has many benefits, including improving patients’ quality of life; reducing distress, anxiety, and depression; contributing to medical cost offsets; and reducing emergency department visits and hospitalizations. Unfortunately, many distressed patients do not receive needed services. There are several multilevel barriers that represent key challenges to DM and affect its implementation. The Consolidated Framework for Implementation Research was used as an organizational structure to outline the barriers and facilitators to implementation of DM, including: 1) individual characteristics (individual patient characteristics with a …

Solving Patients With Rare Diseases Through Programmatic Reanalysis Of Genome-Phenome Data., Leslie Matalonga, Carles Hernández-Ferrer, Davide Piscia, Rebecca Schüle, Matthis Synofzik, Ana Töpf, Lisenka E L M Vissers, Richarda De Voer, Raul Tonda, Steven Laurie, Marcos Fernandez-Callejo, Daniel Picó, Carles Garcia-Linares, Anastasios Papakonstantinou, Alberto Corvó, Ricky Joshi, Hector Diez, Ivo Gut, Alexander Hoischen, Holm Graessner, Sergi Beltran, Solve-Rd Consortia, Peter N Robinson

Faculty Research 2021

Reanalysis of inconclusive exome/genome sequencing data increases the diagnosis yield of patients with rare diseases. However, the cost and efforts required for reanalysis prevent its routine implementation in research and clinical environments. The Solve-RD project aims to reveal the molecular causes underlying undiagnosed rare diseases. One of the goals is to implement innovative approaches to reanalyse the exomes and genomes from thousands of well-studied undiagnosed cases. The raw genomic data is submitted to Solve-RD through the RD-Connect Genome-Phenome Analysis Platform (GPAP) together with standardised phenotypic and pedigree data. We have developed a programmatic workflow to reanalyse genome-phenome data. It uses …

Solving Unsolved Rare Neurological Diseases-A Solve-Rd Viewpoint., Rebecca Schüle, Dagmar Timmann, Corrie E Erasmus, Jennifer Reichbauer, Melanie Wayand, Bart Van De Warrenburg, Ludger Schöls, Carlo Wilke, Andrea Bevot, Stephan Zuchner, Sergi Beltran, Steven Laurie, Leslie Matalonga, Holm Graessner, Matthis Synofzik, Solve-Rd Consortium, Peter N Robinson

Faculty Research 2021

No abstract provided.

Amulet: A Novel Read Count-Based Method For Effective Multiplet Detection From Single Nucleus Atac-Seq Data., Asa Thibodeau, Alper Eroglu, Christopher S Mcginnis, Nathan Lawlor, Djamel Nehar-Belaid, Romy Kursawe, Radu Marches, Daniel N Conrad, George A Kuchel, Zev J Gartner, Jacques Banchereau, Michael L. Stitzel, A Ercument Cicek, Duygu Ucar

Faculty Research 2021

Detecting multiplets in single nucleus (sn)ATAC-seq data is challenging due to data sparsity and limited dynamic range. AMULET (ATAC-seq MULtiplet Estimation Tool) enumerates regions with greater than two uniquely aligned reads across the genome to effectively detect multiplets. We evaluate the method by generating snATAC-seq data in the human blood and pancreatic islet samples. AMULET has high precision, estimated via donor-based multiplexing, and high recall, estimated via simulated multiplets, compared to alternatives and identifies multiplets most effectively when a certain read depth of 25K median valid reads per nucleus is achieved.

Responding In A Pandemic: Student Nurse Educator Mentorships, The Other Side Of Blackboard, Audrey C. Tolouian, Diane B. Monsivais, Melissa Wholeben

Nursing Faculty Publications

Background: Nurse educators who are novice often express the need for improved preparation in the educator role. Problem: With the growth of online programs, one area of concern is the need for educators who are prepared to teach online. Approach: A mentorship for online teaching was developed to give student nurse educators the opportunity to develop educator competencies in the online environment. The process, benefits, challenges, and key points for the success of the mentorship are discussed. Outcomes: Since Spring 2016, 89 nurse educator graduate students have completed the mentorship. Their confidence related to the educator role in an online …

2021-09-01_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled. COVID case and testing data will be posted three times a week on Mondays, Wednesdays and Fridays.

This report is provisional and subject to change. City of Detroit and Wayne County are reported separately. MDHHS began tracking probable cases April 5, 2020. FCI indicates federal correctional institute. MDOC indicates Michigan Department of Corrections. Diagnostic tests, including nucleic acid amplification/real-time …