Medicine and Health Sciences Commons^™

Treatment Of Implant Labial Soft Tissue Dehiscence With Guided Bone Regeneration Vs Subepithelial Connective Tissue Graft. A Randomized Clinical Trial, Mahmoud El-Rayes, Waleed F. Esmael, Mohamed Atef, Lobna Abdelaziz

Future Dental Journal

Background: Implant soft tissue dehiscence is a frequently reported esthetic complication, that more often than not affects the functional integrity of the dental implant with eventual loss of osteointegration. Many treatment modalities with different success rates have been proposed aiming to solve this complication or prolong the survival of the dental implant, of which are guided bone regeneration and soft tissue regeneration around the affected implants.

Material and Methods: This prospective study was carried in the hospital of Future University. 11 Patients (1 Male – 10 Females) with 20 Maxillary implant sites demonstrating soft tissue dehiscence were randomly allocated to …

Three-Dimensional Maxillary Alveolar Ridge Augmentation Using Modified Cortical Shell Technique And Composite Bone Graft, Mostafa Azab, Mohammed Diaa, Waleed El-Beialy, Amr Amin Ghanem

Future Dental Journal

Objective: The present study was performed to assess the 3D alveolar ridge augmentation using the cortical shell from retromolar region and composite bone particulate regarding the width of the residual alveolar ridge. Methods: Thirteen patients with age range 21-40 years old having atrophic anterior maxillary ridge ≤3mm horizontally were included in the study. All patients were subjected to ridge augmentation using composite bone graft and retromolar cortical shell that was fixed in place by two micro-screws. The alveolar ridges were assessed and compared by cone beam computed tomography (CBCT) in the pre-operative, immediate and 4 months post-operative phases by taking …

Postoperative Pain After Different Root Canal Irrigant Activation Methods; (Randomized Clinical Trial), Yasmine Ashraf Abou Khalaf, Ahmed Abdelrahman Hashem, Wael H. Kamel, Mahmoud Mohamed Badr

Future Dental Journal

Objective: This study was designated to evaluate postoperative pain in irreversible symptomatic teeth after different irrigation activation methods using visual analogue scale. Materials and Methods:78 Patients having symptomatic irreversible pulpitis in mandibular first molar (vital pulp) with no periapical involvement were involved in the study. Cases were classified into three groups according to the the final irrigation agitation method used, twenty-six patients each group (n=26). Group A: Root canals were irrigated using NaOCl2* 2.6% with NaviTip (31-gauge 27mm) with double side port irrigator tip (SVN). Group B: Root canals were irrigated using 2.6% NaOCl with manual dynamic agitation using master …

Bilateral Nummular Infiltrates: An Uncommon Presentation Of Candida Keratitis, Deena Dahshan, Charles D Francis, Maya S. Bitar

Ophthalmology Faculty Publications

No abstract provided.

2021-11-09_Michiganoverview_Covidlongtermcare, Michigan Department Of Health & Human Services

Michigan COVID-19 Long Term Care Data

The COVID Long Term Care Facilities page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173-526911--,00.html.

This report is created by the Michigan Department of Health & Human Services from data self-reported by long-term care facilities into EMResource. Data for all reporting facilities is posted weekly each Monday.

The information below represents COVID-19 data reported directly to MDHHS by licensed and operating Skilled Nursing, Home for the Aged and Adult Foster Care facilities (licensed to serve 13 or more individuals) in Michigan from January 1, 2020. All long-term care facilities additionally have an obligation to report COVID-positive residents and/or staff …

Coronavirus Update 11-9-21, The Coronavirus Planning Team

University Briefings & Virtual Events

Pre-holiday Testing: We are offering the opportunity to be tested for those who want to ensure they are negative before traveling home.

Type Vi Secretion System Mutations Reduced Competitive Fitness Of Classical Vibrio Cholerae Biotype, Benjamin Kostiuk, Francis J. Santoriello, Laura Diaz-Satizabal, Fabiana Bisaro, Kyung-Jo Lee, Anna N. Dhody, Daniele Provenzano, Daniel Unterweger, Stefan Pukatzki

Publications and Research

The gram-negative bacterium Vibrio cholerae is the causative agent of the diarrhoeal disease cholera and is responsible for seven recorded pandemics. Several factors are postulated to have led to the decline of 6th pandemic classical strains and the rise of El Tor biotype V. cholerae, establishing the current 7th pandemic. We investigated the ability of classical V. cholerae of the 2nd and 6th pandemics to engage their type six secretion system (T6SS) in microbial competition against non-pandemic and 7th pandemic strains. We report that classical V. cholerae underwent sequential mutations in T6SS genetic determinants that initially exposed 2nd pandemic strains …

Musical Instrument Familiarity Affects Statistical Learning Of Tone Sequences., Stephen C Van Hedger, Ingrid Johnsrude, Laura J Batterink

Brain and Mind Institute Researchers' Publications

Most listeners have an implicit understanding of the rules that govern how music unfolds over time. This knowledge is acquired in part through statistical learning, a robust learning mechanism that allows individuals to extract regularities from the environment. However, it is presently unclear how this prior musical knowledge might facilitate or interfere with the learning of novel tone sequences that do not conform to familiar musical rules. In the present experiment, participants listened to novel, statistically structured tone sequences composed of pitch intervals not typically found in Western music. Between participants, the tone sequences either had the timbre of artificial, …

Estrogens Regulate Placental Angiogenesis In Horses, Shingo Haneda, Pouya Dini, Alejandro Esteller-Vico, Kirsten E. Scoggin, Edward L. Squires, Mats H. T. Troedsson, Peter Daels, Yasuo Nambo, Barry A. Ball

Maxwell H. Gluck Equine Research Center Faculty Publications

A sufficient vascular network within the feto-maternal interface is necessary for placental function. Several pregnancy abnormalities have been associated with abnormal vascular formations in the placenta. We hypothesized that growth and expansion of the placental vascular network in the equine (Equus caballus) placenta is regulated by estrogens (estrogen family hormones), a hormone with a high circulating concentration during equine gestation. Administration of letrozole, a potent and specific inhibitor of aromatase, during the first trimester (D30 to D118), decreased circulatory estrone sulfate concentrations, increased circulatory testosterone and androstenedione concentrations, and tended to reduce the weight of the fetus ( …

Covid-19 Newsletter (Vol. 94), Center For Disaster Medicine, New York Medical College

COVID-19 Newsletter

No abstract provided.

Development Of Gluten-Free Sugar Cookies Using Kudzu Starch As A Partial Fat Replacement Ingredient, Saabirah Carr

Honors College Theses

The prevalence of kudzu has risen in the United States since its introduction in 1876. Though its invasiveness may play a negative role in our ecosystems, its roots have been used nutritionally in China for over 2,000 years because of their high starch content. In the United States, the use of kudzu starch as food products is limited. This study compared the moisture content and spread of reduced-fat gluten-free cookies prepared with kudzu starch-thickened aqueous mixture to similar gluten-free cookies prepared with rice flour and gluten-containing all-purpose wheat flour sugar cookies with kudzu starch, to gluten-containing sugar cookies (control). Moisture …

Cancer Vaccines And Immunotherapy For Tumor Prevention And Treatment, Jagmohan Singh, Wilbur Bowne, Adam E. Snook

Kimmel Cancer Center Faculty Papers

In this editorial, we highlight articles published in this Special Issue of Vaccines on "Cancer Vaccines and Immunotherapy for Tumor Prevention and Treatment", recent developments in the field of cancer vaccines, and the potential for immunotherapeutic combinations in cancer care. This issue covers important developments and progress being made in the cancer vaccine field and possible future directions for exploring new technologies to produce optimal immune responses against cancer and expand the arena of prophylactic and therapeutic cancer vaccines for the treatment of this deadly disease.

Postoperative Outcomes In Oesophagectomy With Trainee Involvement., Oesophago-Gastric Anastomosis Study Group (Ogaa) On Behalf Of The West Midlands Research Collaborative

Department of Surgery Faculty Papers

BACKGROUND: The complexity of oesophageal surgery and the significant risk of morbidity necessitates that oesophagectomy is predominantly performed by a consultant surgeon, or a senior trainee under their supervision. The aim of this study was to determine the impact of trainee involvement in oesophagectomy on postoperative outcomes in an international multicentre setting.

METHODS: Data from the multicentre Oesophago-Gastric Anastomosis Study Group (OGAA) cohort study were analysed, which comprised prospectively collected data from patients undergoing oesophagectomy for oesophageal cancer between April 2018 and December 2018. Procedures were grouped by the level of trainee involvement, and univariable and multivariable analyses were performed …

Quality Evaluation Of Consumer Health Information Websites Found On Google Using Discern, Craap, And Honcode, Ivan A. Portillo, Catherine V. Johnson, Scott Y. Johnson

Library Articles and Research

Online health misinformation is a growing problem, and health information professionals and consumers would benefit from an evaluation of health websites for reliability and trustworthiness. Terms from the Google COVID-19 Search Trends dataset were searched on Google to determine the most frequently appearing consumer health information websites. The quality of the resulting top five websites was evaluated. The top five websites that appeared most frequently were WebMD, Mayo Clinic, Healthline, MedlinePlus, and Medical News Today, respectively. All websites, except Medline Plus, received HONcode certification. Based on DISCERN and CRAAP scores, MedlinePlus was found to be the most reliable health website.

Trends In The Incidence Of Early-Onset Colorectal Adenocarcinoma Among Black And White Us Residents Aged 40 To 49 Years, 2000-2017., Eric M Montminy, Meijiao Zhou, Lauren Maniscalco, Harrison Penrose, Timothy Yen, Swati G Patel, Xiao-Cheng Wu, Jordan J Karlitz

School of Public Health Faculty Publications

Key Points: Question: What are the trends in early-onset colorectal cancer incidence rates when people aged 40 to 49 years are assessed specifically and stratification by race, sex, and adenocarcinoma histology (the target of screening and prevention) is performed? Findings: In this cross-sectional study of 45 429 individuals aged 40 to 49 years with colorectal adenocarcinoma from 2000 to 2017, beginning in 2014, overall colorectal adenocarcinoma incidence rates were the same in Black and White populations, and rectal adenocarcinoma rates were 39.3% lower in Black individuals compared with White individuals with a widening disparity in rectal cancer between Black women …

Improving Patient Satisfaction By Utilizing A Chief Experience Officer, Kathleen G. Spangler

Graduate Theses, Dissertations, and Capstones

With the rapid changes in healthcare and rising costs, improving the patient experience has emerged as a vital healthcare priority among all nations. Many healthcare organizations have responded by creating positions such as the Chief Experience Officer (CXO). This person can play a crucial role as the system champion to lead initiatives to help hospital staff, administrators, and executive leaders focus on patient satisfaction, thus leading to improved patient outcomes/experiences. A descriptive nonexperimental survey design was used to evaluate this project, with the aim of validating the positive influence of the CXO in improving patient satisfaction and experience within the …

November 2021, Swosu Bulldog Wellness Committee

SWOSU BULLDOG WELLNESS

November is American Diabetes Month®
Approximately 373,824 people in Oklahoma have diagnosed diabetes.

An estimated 1,040,000 people in Oklahoma have prediabetes. Take the following survey to find your risk for type 2 diabetes. You will also be given the opportunity to request to be contacted by the SWOSU College of Pharmacy Rural Health Diabetes Prevention Program for upcoming group classes.
Type 2 Diabetes Risk Test: https://swosu.formstack.com/forms/prescreening_questionnaire_dpp

Inability To Switch From Arid1a-Baf To Arid1b-Baf Impairs Exit From Pluripotency And Commitment Towards Neural Crest Formation In Arid1b-Related Neurodevelopmental Disorders, Luca Pagliaroli, Patrizia Porazzi, Alyxandra T Curtis, Chiara Scopa, Harald M M Mikkers, Christian Freund, Lucia Daxinger, Sandra Deliard, Sarah A Welsh, Sarah Offley, Connor A Ott, Bruno Calabretta, Samantha A Brugmann, Gijs W E Santen, Marco Trizzino

Department of Biochemistry and Molecular Biology Faculty Papers

Subunit switches in the BAF chromatin remodeler are essential during development. ARID1B and its paralog ARID1A encode for mutually exclusive BAF subunits. De novo ARID1B haploinsufficient mutations cause neurodevelopmental disorders, including Coffin-Siris syndrome, which is characterized by neurological and craniofacial features. Here, we leveraged ARID1B+/- Coffin-Siris patient-derived iPSCs and modeled cranial neural crest cell (CNCC) formation. We discovered that ARID1B is active only during the first stage of this process, coinciding with neuroectoderm specification, where it is part of a lineage-specific BAF configuration (ARID1B-BAF). ARID1B-BAF regulates exit from pluripotency and lineage commitment by attenuating thousands of enhancers and genes of …

Exercise Prescription Practices In University Counseling Centers: Testing The Information-Motivation-Behavioral Skills Model, A'Naja M. Newsome

USF Tampa Graduate Theses and Dissertations

The co-occurence of physical inactivity and poor mental health in the college student population can lead to chronic health issues that have negative short-term (e.g., academic success and weight gain) and long-term (e.g., obesity, serious mental illness, and premature mortality) impacts. Integrating exercise prescription into the mental health treatment plan of college students could enhance the holistic care model described by The American College Health Association (ACHA) and Healthy Campus task force. Understanding the knowledge, attitudes, and skills that mental health professionals (MHPs) hold regarding exercise prescription is important for policy formation and program development for college student health. The …

Candida Albicans Elicits Protective Allergic Responses Via Platelet Mediated T Helper 2 And T Helper 17 Cell Polarization, Yifan Wu, Zhimin Zeng, Yubiao Guo, Lizhen Song, Jill E Weatherhead, Xinyan Huang, Yuying Zeng, Lynn Bimler, Cheng-Yen Chang, John M Knight, Christian Valladolid, Hua Sun, Miguel A Cruz, Bernhard Hube, Julian R Naglik, Amber U Luong, Farrah Kheradmand, David B Corry

Faculty, Staff and Student Publications

Fungal airway infection (airway mycosis) is an important cause of allergic airway diseases such as asthma, but the mechanisms by which fungi trigger asthmatic reactions are poorly understood. Here, we leverage wild-type and mutant Candida albicans to determine how this common fungus elicits characteristic Th2 and Th17 cell-dependent allergic airway disease in mice. We demonstrate that rather than proteinases that are essential virulence factors for molds, C. albicans instead promoted allergic airway disease through the peptide toxin candidalysin. Candidalysin activated platelets through the Von Willebrand factor (VWF) receptor GP1bα to release the Wnt antagonist Dickkopf-1 (Dkk-1) to drive Th2 and …

Ultrafiltration Rate And Incident Atrial Fibrillation Among Older Individuals Initiating Hemodialysis, Jennifer E Flythe, Sai Liu, Maria E Montez-Rath, Wolfgang C Winkelmayer, Tara I Chang

Faculty, Staff and Students Publications

BACKGROUND: Higher ultrafiltration (UF) rates are associated with numerous adverse cardiovascular outcomes among individuals receiving maintenance hemodialysis. We undertook this study to investigate the association of UF rate and incident atrial fibrillation in a large, nationally representative US cohort of incident, older hemodialysis patients.

METHODS: We used the US Renal Data System linked to the records of a large dialysis provider to identify individuals ≥67 years of age initiating hemodialysis between January 2006 and December 2011. We applied an extended Cox model as a function of a time-varying exposure to compute adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) …

Storytelling To Improve Disease Outcomes In Gout (Stride-Go): A Multicenter, Randomized Controlled Trial In African American Veterans With Gout, Jasvinder A Singh, Amy Joseph, Joshua Baker, Joshua S Richman, Terrence Shaneyfelt, Kenneth G Saag, Seth Eisen

2020-Current year OA Pubs

BACKGROUND: Urate-lowering therapy (ULT) adherence is low in gout, and few, if any, effective, low-cost, interventions are available. Our objective was to assess if a culturally appropriate gout-storytelling intervention is superior to an attention control for improving gout outcomes in African-Americans (AAs).

METHODS: In a 1-year, multicenter, randomized controlled trial, AA veterans with gout were randomized to gout-storytelling intervention vs. a stress reduction video (attention control group; 1:1 ratio). The primary outcome was ULT adherence measured with MEMSCap™, an electronic monitoring system that objectively measured ULT medication adherence.

RESULTS: The 306 male AA veterans with gout who met the eligibility …

Role Of Aim2 Inflammasome In Pulmonary Host Defense Against Staphylococcus Aureus-Induced Pneumonia, Bibek Dhakal

LSU Master's Theses

Bacterial pneumonia is the leading cause of death in children under the age of five, claiming the lives of two million children each year. Staphylococcus aureus is the extracellular Gram-positive bacteria that causes necrotizing pneumonia. Moreover, the spread of antibiotic-resistant and hypervirulent strains has made treatment more challenging. Absent in melanoma 2 (AIM2) is a dsDNA-sensing cytosolic innate immune receptor that activates inflammasomes and is crucial for host defense against intracellular bacteria and DNA viruses. However, its role in extracellular bacterial pathogen-induced pneumonia is unclear. Therefore, understanding how AIM2 initiates host responses during Staphylococcus aureus is crucial for the development …

Assessment Of Middle-Distance Runners Cardiovascular System In Rest And Load Conditions, Rashid Akhadovich Burnashev

Eurasian Journal of Sport Science

Purpose: Assessment of cardiovascular response of qualified middle-distance runners to aerobic and anaerobic physical loads.

Methods: Qualified middle-distance runners at the stage of sportsmanship improvement (n = 20) were studied. Sports qualification - 2 and 1 categories. The analysis of Heart Rate Variability was carried out using the application “CardioMood” with “Polar h10” and “Polar M430”. A 5-minute electrocardiogram recording was performed. Only normal NN cardio cycles were studied. When analyzing Heart Rate Variability, the following parameters were obtained: HR, SDNN, pNN50, TP, entropy (H), modes (Mo), AMo, stress index. The complex “vegetative indicator” was calculated. Statistical processing of obtained …

Traumatic Stress In Families, Joanna Burkhardt

Library Impact Statements

No abstract provided.

2021-11-08_Michiganoverview_Covidoutbreak, Michigan Department Of Health & Human Services

Michigan COVID-19 Outbreak Reports

The Outbreak Data page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173_102057---,00.html.

This report is created by the Michigan Department of Health & Human Services from data self-reported by local health departments. Data is updated every week.

COVID-19 outbreaks are generally defined as two or more cases with a link by place and time indicating a shared exposure outside of a household. Local health departments report the number of new and ongoing outbreaks they are investigating by the setting of the outbreak. New outbreaks are those outbreaks that were first identified during the current reporting week. Ongoing outbreaks are …

Apoe Gene Associated With Cholesterol-Related Traits In The Hispanic Population, Stephanie Lozano, Victoria Padilla, Manuel Lee Avila, Mario Gil, Gladys Maestre, Kesheng Wang, Chun Xu

Faculty & Staff Scholarship

Genetic variants in the apolipoprotein E (APOE) gene are associated with lipid metabolism and lipid-related traits in the non-Hispanic population. There have been limited studies regarding the association between the APOE gene and hypercholesterolemia in the Hispanic population; therefore, our aim for this study is to examine the APOE gene’s associations with cholesterol level and its related phenotypes. The APOE gene consists of three different alleles, ε2, ε3, and ε4, with ε4 being associated with dementia and cardiovascular diseases. A total of 1,382 subjects were collected from the Texas Alzheimer’s Research and Care Consortium (TARCC, N = 1320) and the …

Improving Data Collection And Documentation Within A Post-Hospital Discharge Follow-Up Phone Call Program, Lindsay Horihan, Tasha Flicek

Nursing DNP Projects

Hospital discharge with quality patient education and instruction is paramount for the success of recovery and mitigation of readmission. Identification of gaps within hospital discharge can lead to strategies to improve the discharge process. A project was designed to improve data collection, documentation of discrepancies (gaps/events), and analysis of data relating to patient and process outcomes of a post-discharge follow-up phone call program. Interventions included a newly implemented algorithm to outline a phone call workflow, refine data collection, and evaluate outcomes. Data collection to increase identification of gaps in care from discharge to follow-up aid in improving patient outcomes.

2021-11-08_Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

Contains the tables Statewide Hospital Capacity Report for COVID-19, COVID-19 Metrics, Statewide Hospital Available PPE Tracking for COVID-19, as well as the tables PPE Days On Hand and Patient Census.

2021-11-08_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …