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2021

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Articles 18811 - 18840 of 21398

Full-Text Articles in Medicine and Health Sciences

Power Of Body Live Weights In Differentiation Physiological Growth Of Goat Breeds, Raed Alatiyat, Amani Al-Dawood Jan 2021

Power Of Body Live Weights In Differentiation Physiological Growth Of Goat Breeds, Raed Alatiyat, Amani Al-Dawood

Turkish Journal of Veterinary & Animal Sciences

We assumed that live body weight (LBW) would be useful to be utilized as informative categorical variable in differentiation goat performance towards better assignment into breeds. One-day old goat kids of both sexes were separately allocated as 3 breeds: Baladi, crossbreds and Shami. The kid LBW was recorded weekly until the 12th week of age. Weekly LBW showed a significant increase (p < 0.05) for both males and females of the 3 breeds and highly significant (p < 0.0001) between breeds. The high phenotypic correlation between most of the studied measurements encouraged us to investigate their efficiency in breed differentiation at early life age. Results showed that only LBW of the week 1, 2, 5, 9, and 11, and week 1, 2, 3, 11, and 12 were efficient in discriminating male and female kids, respectively. These results were better presented by showing significant genetic distances (p < 0.0001) between the breeds using the Unweighted Pair Group Method with Arithmetic mean (UPGMA) dendrogram. It is inferred that the phylogenetic tree lengths of the three breeds were 29.02 and 222.13 for male and female kids, respectively. Baladi and crossbred kids of both sexes grouped into one cluster closer than Shami kids. The canonical discriminant analysis was proved its successfulness for identifying breed based on LBW measurement.

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An Assessment Of Ensiling Potential In Maize X Legume (Soybean And Cowpea) Binarymixtures For Yield And Feeding Quality, Erdem Gülümser, Hani̇fe Mut, Uğur Başaran, Medi̇ne Çopur Doğrusöz Jan 2021

An Assessment Of Ensiling Potential In Maize X Legume (Soybean And Cowpea) Binarymixtures For Yield And Feeding Quality, Erdem Gülümser, Hani̇fe Mut, Uğur Başaran, Medi̇ne Çopur Doğrusöz

Turkish Journal of Veterinary & Animal Sciences

In this study, maize and legume intercropping were evaluated in terms of silage yield and quality. Maize (Zea mays L.''M'') was intercropped with soybean (Glycine max L. ''S'') and cowpea (Vigna unguiculata L. ''C'') as binary mixtues (maize + legume), and the seed rates were as follows: 100 + 0%, 75 + 25%, 50 + 50% and 25 + 75%. The harvested plants were chopped with the particle size of < 2, ensiled in 2 kg plastic jars and left fermentation at 25 ± 2 °C for 45 days. In this study, silage yield, dry matter ratio, pH value, crude protein ratio, acid detergent fiber, neutral detergent fiber, digestibility of dry matter, dry matter intake, total digestibil nutrient relative feed values, lactic acid, acetic acid, butyric acid, malic acid, citric acid, succinic acid, oxalic acid, potassium, phosphorus, calcium, and magnesium contents were determined. All the M + S mixtures showed high performance in terms of Flieg score and lactic acid content. The highest relative feed quality value was determined in the sole cowpea (156.4) and 25M + 75S% (148.5) mixture. As a result, intercropping maize with legumes resulted in superior silage quality without a reduction in yield.

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Investigation Of Relationships Between Placental Characteristics And Kid Birth Weight Ingoats, Çağri Kandemi̇r, Fatma Akkaya, Turğay Taşkin, Bi̇sem Ni̇sa Kandemi̇r Jan 2021

Investigation Of Relationships Between Placental Characteristics And Kid Birth Weight Ingoats, Çağri Kandemi̇r, Fatma Akkaya, Turğay Taşkin, Bi̇sem Ni̇sa Kandemi̇r

Turkish Journal of Veterinary & Animal Sciences

The aim of this study was to determine the relationships among the kid birth weight, the placental, and cotyledon traits in Saanen goats. The effect of parity, birth type, and birth weight (BIRWT), on placental and cotyledon characteristics, were analyzed by the general linear model. Significant differences for birth type occurred on cotyledon length (CL) and cotyledon depth (CDEP). The means for cotyledon width (CWID) and cotyledon depth (CDEP) were 21.52 and 0.361 mm, respectively. The general means of total cotyledon surface area (TCSA), cotyledon number (CN), and cotyledon weight (CWE) were 67.27 cm$^{2}$, 66.76 unit, and 153.51 g, respectively. …

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Variations In The Median Sacral Crest And Angulation Of The First Sacral Spinous Process Associated With Sacrocaudal Fusion In Greyhounds, Saad M. Y. Ismail, Christina M. Murray, Mark A. Stevenson, Hung-Hsun Yen, Helen M. S. Davies Jan 2021

Variations In The Median Sacral Crest And Angulation Of The First Sacral Spinous Process Associated With Sacrocaudal Fusion In Greyhounds, Saad M. Y. Ismail, Christina M. Murray, Mark A. Stevenson, Hung-Hsun Yen, Helen M. S. Davies

Turkish Journal of Veterinary & Animal Sciences

The current study aimed to investigate the association between the morphology of the median sacral crest, variation in the angle of the spinous process of the first sacral vertebra, and the occurrence of sacrocaudal fusion in greyhounds. In this study, 167 sacra from cadavers of greyhounds (previously euthanized for reasons unrelated to this study) were collected, classified into standard and fuses sacra (based on the number of fused vertebrae and type of fusion), and then classified based on the morphology of the median sacral crest into three different types: type F (full crest), type N (when the median sacral crest …

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Effects Of Feed Restriction On The Occurrence Of White Striping And Wooden Breast Myopathies, Performance, Carcass Characteristics And Some Blood Parameters In Broiler Chickens, Hayri̇ye Değer Oral Toplu, Serap Ünübol Aypak, Ahmet Nazligül, Mehmet Kaya Jan 2021

Effects Of Feed Restriction On The Occurrence Of White Striping And Wooden Breast Myopathies, Performance, Carcass Characteristics And Some Blood Parameters In Broiler Chickens, Hayri̇ye Değer Oral Toplu, Serap Ünübol Aypak, Ahmet Nazligül, Mehmet Kaya

Turkish Journal of Veterinary & Animal Sciences

This study was planned to determine the effects of feed restriction applied at different times and levels on the occurrence of white striping and wooden breast myopathies, performance, carcass characteristics and some blood parameters in broilers. In total, 600 male broilers were randomly placed to 5 groups with eight replicates. Control group was fed ad libitum throughout experimental period. T1 and T2 groups received feed as 80% and 70% of control group from 11 to 24 days of age, respectively. T3 and T4 groups received feed as 80% and 70% of control group from 25 to 39 days of age, …

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Mediator Margins In The Dairy Supply Chain And Factors Influencing Marketing Preferences In Eastern Mediterranean Region Of Turkey, Mehmet Feri̇t Can, Ayteki̇n Günlü, Yilmaz Aral, Tuğba Sarihan Şahi̇n, Mehmet Saltuk Arikan Jan 2021

Mediator Margins In The Dairy Supply Chain And Factors Influencing Marketing Preferences In Eastern Mediterranean Region Of Turkey, Mehmet Feri̇t Can, Ayteki̇n Günlü, Yilmaz Aral, Tuğba Sarihan Şahi̇n, Mehmet Saltuk Arikan

Turkish Journal of Veterinary & Animal Sciences

The purpose of this study is to identify the shares of the intermediaries in the Eastern Mediterranean region milk supply chain (I) and to estimate the factors influencing the raw milk marketing preferences of milk producers (II). The research was conducted in 2017 with 102 dairy farms and 36 dairy industry enterprises in Hatay, Kahramanmaraş, and Osmaniye provinces. As a result of the research, it was found that 85% of the milk produced by dairy farms was offered to the market, 65% of the milk entering the supply chain was transferred to the dairy industry and the average capacity utilization …

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Comparative Efficiency Of Five Mathematical Functions In Modelling The First Lactation Milk Yield Of Kankrej Cattle, Thiruvothur Venkatesan Raja, Achintya Kumar Das, Satish Kumar Rathee, Umesh Singh, Sushil Kumar, Bharat Singh Rathod, Harshad Panchasara Jan 2021

Comparative Efficiency Of Five Mathematical Functions In Modelling The First Lactation Milk Yield Of Kankrej Cattle, Thiruvothur Venkatesan Raja, Achintya Kumar Das, Satish Kumar Rathee, Umesh Singh, Sushil Kumar, Bharat Singh Rathod, Harshad Panchasara

Turkish Journal of Veterinary & Animal Sciences

Modelling of first lactation milk yield of Kankrej cattle was done using five different non-linear mathematical functions viz., exponential decline function (EDF), gamma function (GF), inverse polynomial function (IPF), mixed log function (MLF) and parabolic exponential function (PEF). We compared their efficiency in describing variations in first lactation milk yield of animals maintained under field conditions. A total of 3994 fortnightly daily milk records of 203 Kankrej cattle calved during the years between 2011 and 2017 at farmers? herds in the Banaskantha region of Gujarat State, India were utilized for the study. The PROC NLIN procedure of Statistical Analysis Software …

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Evaluation Of Cyp19 As A Candidate Gene For Milk Production Traits In Native Cattle Andbuffalo Populations Of Southern India, Sudhakar Krovvidi, Thiruvenkadan Kannan Aranganoor, Saravanan Ramasamy, Vinoo Regula, Muralidhar Metta, Jeyakumar Mani Jan 2021

Evaluation Of Cyp19 As A Candidate Gene For Milk Production Traits In Native Cattle Andbuffalo Populations Of Southern India, Sudhakar Krovvidi, Thiruvenkadan Kannan Aranganoor, Saravanan Ramasamy, Vinoo Regula, Muralidhar Metta, Jeyakumar Mani

Turkish Journal of Veterinary & Animal Sciences

Candidate gene approach facilitates searching causative polymorphisms that influence quantitative traits. Biosynthesis of estrogen catalyzed by aromatase, a product of the CYP19 gene affect lactogenesis. The objective of the study was to determine the polymorphism in the promoter region of CYP19 gene by PCR-RFLP and was undertaken on 502 bovine species belonging to Ongole (Bos indicus), Holstein Friesian crossbred, Jersey crossbred cattle, and Murrah buffaloes reared across Southern India. The frequency of the CYP19A allele was 0.90, 0.88, and 0.77 in Jersey crossbred, HF crossbred, and Ongole cattle, respectively. The BB genotypes could not be observed in Jersey crossbred cattle. …

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In Vitro Gas Production And Fatty Acids Biohydrogenation Of Diets Containing Different Unsaturated Fatty Acids Sources Plus Crude Glycerin, Arturo Samuel Gomez Insuasti, Yury Tatiana Granja-Salcedo, Julian Andres Castillo Vargas, Juliana Duarte Messana, Ana Paula De Oliveira Sader, Telma Teresinha Berchielli Jan 2021

In Vitro Gas Production And Fatty Acids Biohydrogenation Of Diets Containing Different Unsaturated Fatty Acids Sources Plus Crude Glycerin, Arturo Samuel Gomez Insuasti, Yury Tatiana Granja-Salcedo, Julian Andres Castillo Vargas, Juliana Duarte Messana, Ana Paula De Oliveira Sader, Telma Teresinha Berchielli

Turkish Journal of Veterinary & Animal Sciences

An in vitro trial was conducted to evaluate the effects of different unsaturated fatty acids (UFA) sources plus crude glycerin (CGL) on gas production and rumen biohydrogenation (RBH). Incubated diet corresponded to diets containing corn silage (30%) and concentrate (70%) composed of corn, urea, mineral salts, CGL, and different UFA sources as follows: no additional fat (NAF), rumen protected fat (RPF), soybean oil, linoleic acid (LA) or alpha-linolenic acid (LN). Methane concentrations in LA and LN were lower compared to NAF (p < 0.001), but when CH4 was expressed as a proportion of total gas, NAF and RPF showed the greatest values among evaluated UFA sources (p = 0.001). 18:1 t11 concentration showed a faster increase from 0 to 1 h and a slower decrease from 1 to 36 h of incubation, irrespective of UFA source. A higher C18:1 t11 production rate was observed from 1 h to 5 h of incubation, where LA and LN have higher values compared to NAF and RPF diets (p < 0.001). Diets with a high content of LA may be efficient as a nutritional approach to reduce methane production and RBH, resulting in positive effects on vaccenic acid concentrations.

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Risk Of Tuberculosis Is Increased In Behçet's Disease Compared To Other Rheumatologicaldisorders After Anti-Tnf∝ Treatments: A Case Series And Review Of The Literature, Ümmügülsüm Gazel, Derya Kocakaya, İrem Hi̇cret Topçu, Hakan Ömer Karataş, Murat Karabacak, Mehmet Pami̇r Atagündüz, Güzi̇de Nevsun İnanç, Fatma Ali̇baz Öner, Rafi̇ Haner Di̇reskeneli̇ Jan 2021

Risk Of Tuberculosis Is Increased In Behçet's Disease Compared To Other Rheumatologicaldisorders After Anti-Tnf∝ Treatments: A Case Series And Review Of The Literature, Ümmügülsüm Gazel, Derya Kocakaya, İrem Hi̇cret Topçu, Hakan Ömer Karataş, Murat Karabacak, Mehmet Pami̇r Atagündüz, Güzi̇de Nevsun İnanç, Fatma Ali̇baz Öner, Rafi̇ Haner Di̇reskeneli̇

Turkish Journal of Medical Sciences

Background/aim: Tumor necrosis factor-alfa (TNF-a) antagonists are extensively utilized in the treatment of inflammatory rheumatic diseases and also shown to be effective in Behçet's disease (BD) patients with major organ involvement. In this study, we aimed to reevaluate the incidence of tuberculosis (TB) infection after anti-TNFa treatments and to reveal the risk of TB in BD. Methods: Data of patients who received anti-TNFa treatment between 2005 and 2018 were assessed retrospectively. Demographic features, TNF-a antagonist type/treatment time, tuberculosis skin test (TST) and QuantiFERON results, isoniazid prophylaxis status, and concomitant corticosteroid (CS) treatments were collected. Results: A total of 1277 (male/female …

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How Important Is The Sphenoseptal Cell In Identifying The Skull Base?Recent Incidence And Demonstration Of Endoscopic Surgical Steps, Cem Saka, Bülent Öcal, Emel Çadalli Tatar, Gökhan Toptaş, Tuğçe Pütürgeli̇ Özer, Mehmet Hakan Korkmaz Jan 2021

How Important Is The Sphenoseptal Cell In Identifying The Skull Base?Recent Incidence And Demonstration Of Endoscopic Surgical Steps, Cem Saka, Bülent Öcal, Emel Çadalli Tatar, Gökhan Toptaş, Tuğçe Pütürgeli̇ Özer, Mehmet Hakan Korkmaz

Turkish Journal of Medical Sciences

Background/aim: Because of close relations to important anatomical structures such as cavernous sinus and optic nerve, sphenoid sinus variations must be well trained by the otolaryngologist who has an interest in endoscopic sinus surgery. Newly defined sphenoseptal cell (SSC) is one of those variations that may lead to insufficient endoscopic sinus surgery outcomes if not defined preoperatively with imaging studies. The present study aimed to present the main characteristics of this special type of nasal cell. Materials and methods: In this study, 610 paranasal sinus CT scans were analyzed and reviewed retrospectively between May 2018 and December 2019. Also, endoscopic …

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Evaluation Of Extensively Drug-Resistant Gram-Negative Bacteremia Among Solid-Organtransplant Recipients: A Multicenter Study, Tuğba Yanik Yalçin, Özlem Azap, Adem Köse, Yaşar Bayindir, Eli̇f Muki̇me Saricaoğlu, Güle Çinar, Yeşi̇m Uygun Kizmaz, Ebru Kurşun, Hi̇kmet Eda Alişkan, Ayşe Yasemi̇n Tezer Tekçe, Oya Özlem Eren Kutsoylu, Tufan Egeli̇, Alpay Ari, Yurdagül Albayrak, Hati̇ce Çabadak Jan 2021

Evaluation Of Extensively Drug-Resistant Gram-Negative Bacteremia Among Solid-Organtransplant Recipients: A Multicenter Study, Tuğba Yanik Yalçin, Özlem Azap, Adem Köse, Yaşar Bayindir, Eli̇f Muki̇me Saricaoğlu, Güle Çinar, Yeşi̇m Uygun Kizmaz, Ebru Kurşun, Hi̇kmet Eda Alişkan, Ayşe Yasemi̇n Tezer Tekçe, Oya Özlem Eren Kutsoylu, Tufan Egeli̇, Alpay Ari, Yurdagül Albayrak, Hati̇ce Çabadak

Turkish Journal of Medical Sciences

Background/aim: The aim of this study is to evaluate the distribution, sources, clinical features, and mortality rates of bacteremia due to evaluation of extensively drug-resistant (XDR) gram negative among solid-organ transplant (SOT) recipients. Materials and methods: A retrospective study of SOT recipients with bacteremia due to XDR gram-negative pathogens in 11 centers between 2016 and 2018 was conducted. Patients' records were evaluated. Results: Of 171 bacteremia that occurred in 164 SOT recipients, 93 (56.7%) were liver, 46 (28%) kidney, 14 (8.5%) heart, and 11 (6.7%) lung recipients. Bacteremia episodes were recorded in the first year in 63.7% of the patients …

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Circulating Mir-29c-3p Is Downregulated In Patients With Acromegaly, Hakan Korkmaz, Kuyaş Heki̇mler Öztürk, Bora Torus Jan 2021

Circulating Mir-29c-3p Is Downregulated In Patients With Acromegaly, Hakan Korkmaz, Kuyaş Heki̇mler Öztürk, Bora Torus

Turkish Journal of Medical Sciences

Background/aim: miRNAs control various biological functions, such as cell proliferation, differentiation, signaling pathways, apoptosis and metabolism. Recently, it has been shown that there is a relationship between changes in miRNA expression and the development of acromegaly. Studies are needed to identify new disease-specific miRNAs. The aim of the current study is to evaluate plasma miR-29c-3p, miR-31-5p and miR-18a-5p steady-state levels in acromegaly. Another aim is to investigate whether there is a difference in the levels of these miRNAs in patients with inadequate control and controlled acromegaly with somatostatin analog (SSA) therapy. These miRNAs targeting the IGF-1 gene were determined by …

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Flow Cytometric Analysis Of Platelet Surface Glycoproteins In The Diagnosis Of Thirty-Twoturkish Patients With Glanzmann Thrombasthenia: A Multicenter Experience, Berkay Saraymen, Sabahatti̇n Muhtaroğlu, Mustafa Yavuz Köker, Nazan Sarper, Emi̇ne Zengi̇n, Canan Albayrak, Davut Albayrak, Osman Bülent Zülfi̇kar, Sayi̇me Başak Koç Şenol, Esma Bentli̇, Semi̇h Yilmaz, Aysun Çeti̇n, Bülent Eser, Mustafa Çeti̇n Jan 2021

Flow Cytometric Analysis Of Platelet Surface Glycoproteins In The Diagnosis Of Thirty-Twoturkish Patients With Glanzmann Thrombasthenia: A Multicenter Experience, Berkay Saraymen, Sabahatti̇n Muhtaroğlu, Mustafa Yavuz Köker, Nazan Sarper, Emi̇ne Zengi̇n, Canan Albayrak, Davut Albayrak, Osman Bülent Zülfi̇kar, Sayi̇me Başak Koç Şenol, Esma Bentli̇, Semi̇h Yilmaz, Aysun Çeti̇n, Bülent Eser, Mustafa Çeti̇n

Turkish Journal of Medical Sciences

Background/aim: Glanzmann thrombasthenia (GT) is a rare autosomal recessively inherited bleeding disorder characterized by the quantitative (type 1 and type 2) or qualitative (type 3) deficiency in platelet membrane glycoprotein (GP) IIb/IIIa (CD41a/CD61) fibrinogen receptors. In type 1, 2, and 3, CD41a/CD61 expression is 5%, 5%-20% and above 20%, respectively. In this study, diagnosis of GT was confirmed and subgroups were identified in 32 Turkish patients by flow cytometry analysis. Materials and methods: CD41a/CD61 expression levels in platelet-rich plasma (PRP) obtained from peripheral venous EDTA blood samples were analyzed with a BD FACSCanto II flow cytometer (Becton Dickinson, Franklin Lakes, …

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Allergic Reactions Against Covıd-19 Vaccines, Hi̇lal Ünsal, Bülent Eni̇s Şekerel, Ümi̇t Murat Şahi̇ner Jan 2021

Allergic Reactions Against Covıd-19 Vaccines, Hi̇lal Ünsal, Bülent Eni̇s Şekerel, Ümi̇t Murat Şahi̇ner

Turkish Journal of Medical Sciences

Coronavirus Disease 2019 (COVID-19) affected the whole world in a short time. One of the most influential public health initiatives modern medicine has to offer, the vaccine has become even more important as the COVID-19 pandemic continues to worsen worldwide. Many vaccine trials were launched during the COVID-19 pandemic, and these vaccines were widely used around the world, offering realistic hope for ending the pandemic. Allergic reactions to vaccines were reported shortly after their approval. These reactions, in general, are rare, but, in some circumstances, they can be serious. Allergy to vaccines can occur because of either the active vaccine …

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Mean Platelet Volume In Familial Mediterranean Fever Related Aa Amyloidosis Andcomparison With Common Primary Glomerular Diseases, Tolga Yildirim, Berranur Kütahya, Fatma İş, Mehmet Erdevi̇r, Müge Üzerk Ki̇bar, Neri̇man Sila Koç, Emi̇ne Arzu Ayhan, Şeref Rahmi̇ Yilmaz, Yunus Erdem Jan 2021

Mean Platelet Volume In Familial Mediterranean Fever Related Aa Amyloidosis Andcomparison With Common Primary Glomerular Diseases, Tolga Yildirim, Berranur Kütahya, Fatma İş, Mehmet Erdevi̇r, Müge Üzerk Ki̇bar, Neri̇man Sila Koç, Emi̇ne Arzu Ayhan, Şeref Rahmi̇ Yilmaz, Yunus Erdem

Turkish Journal of Medical Sciences

Background/aim: Compared to healthy controls, mean platelet volume (MPV) is frequently higher in patients with Familial Mediterranean fever (FMF) but lower in AA amyloidosis patients. The reason for the difference in MPV levels in FMF patients with and without AA amyloidosis is unclear. The aim of the study was to determine whether low MPV is unique to AA amyloidosis or MPV is similarly low in all glomerular diseases as a result of proteinuria and/or renal dysfunction. Materials and methods: We compared pre-biopsy MPV levels of patients with AA amyloidosis secondary to FMF, to MPV levels of patients with membranous glomerulonephritis, …

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Are The Criteria Always Right? Assessment Of Hepatocellular Carcinoma Cases In Livingdonor Liver Transplantation At A High-Volume Center, Yücel Yankol, Gülteki̇n Hoş, Turan Kanmaz, Nesi̇mi̇ Meci̇t, Yilmaz Çakaloğlu, Münci̇ Kalayoğlu, Koray Sadik Acarli Jan 2021

Are The Criteria Always Right? Assessment Of Hepatocellular Carcinoma Cases In Livingdonor Liver Transplantation At A High-Volume Center, Yücel Yankol, Gülteki̇n Hoş, Turan Kanmaz, Nesi̇mi̇ Meci̇t, Yilmaz Çakaloğlu, Münci̇ Kalayoğlu, Koray Sadik Acarli

Turkish Journal of Medical Sciences

Background/aim: With the increased experience in living donor liver transplantation (LDLT), it has been adopted for the treatment of hepatocellular carcinoma (HCC), with emerging discussions of criteria beyond tumor size and number. In contrast to deceased donor liver transplantation (DDLT), recipient selection for LDLT is not limited by organ allocation systems. We discuss herein the assessment, criteria, and experience with liver transplantation (LT) in HCC cases at a high-volume LDLT center. Material and methods: Between August 2006 and December 2017, 191 adult LT HCC recipients with at least one-year follow-up were retrospectively analyzed. Results: In 191 patients, one-, three- and …

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Activation-Induced Cytidine Deaminase Expression In Patients With Myelodysplasticsyndrome And Its Relationship With Prognosis And Treatment, Ege Si̇nan Torun, Aynur Aday, Meli̇ha Nalçaci Jan 2021

Activation-Induced Cytidine Deaminase Expression In Patients With Myelodysplasticsyndrome And Its Relationship With Prognosis And Treatment, Ege Si̇nan Torun, Aynur Aday, Meli̇ha Nalçaci

Turkish Journal of Medical Sciences

Background/aim: Activation-induced cytidine deaminase (AID) enables antibody diversity in B lymphocytes. It may also have an effect on MDS pathogenesis by causing somatic mutations and by inducing epigenetic changes in myeloid cells. This study aimed to compare AID expression of MDS patients with healthy controls, of MDS patients in different risk groups, and of MDS patients according to their treatment. Materials and methods: Total RNA was isolated and complementary DNA (cDNA) was transcribed from the peripheral blood samples of MDS patients and healthy controls. AID and the reference gene HPRT1 were analyzed using quantitative real-time PCR (QRT-PCR). AID expression relative …

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Associations Between The Radiographic Phenotypes And The Presence Of Metabolicsyndrome In Patients With Knee Osteoarthritis, Berna Güzel, Mehmet Derya Demi̇rağ, Düri̇ye Sila Karagöz Özen, Ni̇zametti̇n Güzel, Mukadder Erdem, Berna Göker Jan 2021

Associations Between The Radiographic Phenotypes And The Presence Of Metabolicsyndrome In Patients With Knee Osteoarthritis, Berna Güzel, Mehmet Derya Demi̇rağ, Düri̇ye Sila Karagöz Özen, Ni̇zametti̇n Güzel, Mukadder Erdem, Berna Göker

Turkish Journal of Medical Sciences

Background/aim: We aimed to investigate the associations between the radiographic phenotypes and the presence of metabolic syndrome (MetS) in patients with knee osteoarthritis (OA). Materials and methods: We evaluated women age 40 and over who presented to our outpatient clinics with knee pain and fulfilled the clinical and radiographic criteria for the classification of idiopathic OA of the knee. Patients were categorized into two groups concerning dominant radiographic phenotype. We included consecutive 50 patients in each group. All patients were evaluated in terms of MetS according to the revised diagnostic criteria of the National Cholesterol Education Program Adult Treatment Panel …

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Translation And Validation Of A Turkish Version Of The Xerostomia Inventory Xi Inpatients With Primary Sjögren's Syndrome, Bi̇lge Başakci Çalik, Eli̇f Gür Kabul, Ayli̇n Keski̇n, Si̇nem Bozcuk, Hande Şenol, Veli̇ Çobankara Jan 2021

Translation And Validation Of A Turkish Version Of The Xerostomia Inventory Xi Inpatients With Primary Sjögren's Syndrome, Bi̇lge Başakci Çalik, Eli̇f Gür Kabul, Ayli̇n Keski̇n, Si̇nem Bozcuk, Hande Şenol, Veli̇ Çobankara

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to assess the reliability and validity of Turkish version of the Xerostomia Inventory XI in patients with primary Sjögren's syndrome (pSS). Materials and methods: A cross-sectional survey study design and analysis were used to assess the reliability and validity of the Xerostomia Inventory XI. A total of 69 patients with pSS (5 males, 64 females; mean age = 54.81 ± 8.77 years) were included. The Xerostomia Inventory XI (TR) was applied twice at an interval of 15 days. The test-retest reliability was assessed with the intraclass correlation coefficient (ICC), and the internal consistency …

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Assessment Of Erythrocyte Morphology In Patients With Type 2 Diabetes Mellitus: A Pilotstudy Of Electron Microscopy-Based Analysis In Relation To Healthy Controls, Tülay Mortaş, Şenay Arikan Durmaz, Şaban Cem Sezen, Yasemi̇n Savranlar Jan 2021

Assessment Of Erythrocyte Morphology In Patients With Type 2 Diabetes Mellitus: A Pilotstudy Of Electron Microscopy-Based Analysis In Relation To Healthy Controls, Tülay Mortaş, Şenay Arikan Durmaz, Şaban Cem Sezen, Yasemi̇n Savranlar

Turkish Journal of Medical Sciences

Background/aim: The present study aimed to assess erythrocyte morphology in newly diagnosed type 2 diabetes mellitus patients using scanning electron microscopy. Materials and methods: In total, 30 patients admitted to endocrine outpatient clinics were included in the study. The patients were divided into two groups according to their fasting blood glucose levels: type 2 diabetes mellitus (n = 15, fasting blood glucose levels ≥ 126 mg/dL) and control (n = 15, fasting blood glucose levels < 99 mg/dL). The patient's demographic characteristics, haemoglobin A1c levels, and scanning electron microscopy findings regarding erythrocyte morphology were recorded. Results: There was no significant difference between the control and type 2 diabetes mellitus group in terms of the participants' age (51.13 ± 8.53 vs. 50.33 ± 8.72 years, p = 0.8) and the male/female ratio (9/6 vs. 9/6). In the control group, discocytes were abundant, echinocytes were rare, and spherocytes were absent. On the other hand, discocytes were less common and echinocyte-shaped erythrocytes were more common in the type 2 diabetes mellitus group than in the control group. In addition, spherocytes were detected in the type 2 diabetes mellitus group. Moreover, the diameter of discocytes was significantly lower (p = 0.014), and blood glucose and haemoglobin A1c levels were significantly higher (p < 0.05 for both) in the type 2 diabetes mellitus group than in the control group. Conclusion: Our findings indicate that high glucose levels in type 2 diabetes mellitus patients lead to significant alterations in erythrocyte morphology, including decreased erythrocyte deformability and the formation of echinocytes and spherocytes due to eryptosis. The possibility of decreased erythrocyte deformability due to excessive eryptosis may disturb microcirculation in newly diagnosed, treatment-naïve type 2 diabetes mellitus patients who do not have any complications.

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Clinical Trials Of 3d Printing Splints To Avoid Contracture Development In Burned Children, Ati̇lla Şenayli, Güven Çankaya, Can İhsan Öztorun, Hakan Oflaz, Emrah Şenel Jan 2021

Clinical Trials Of 3d Printing Splints To Avoid Contracture Development In Burned Children, Ati̇lla Şenayli, Güven Çankaya, Can İhsan Öztorun, Hakan Oflaz, Emrah Şenel

Turkish Journal of Medical Sciences

Background/aim: We evaluated the feasibility of producing splints with 3D printer technology to prevent contractures in burned children in our clinical prospective study. Materials and methods: After approvals, children with burns greater than 2nd degree were included in the study. Age, sex, burn percentages, printing time, filament types, number of filament trials, splint suitability, patient and doctor comments, preclinical trials' significances and financial impact were evaluated statistically. Results: Seventy-six trials were conducted on 18 patients. Fourteen of the patients were male and 4 are female. Average ages of boys and girls were 5 and 3, respectively. Burn percentage was 36.9 …

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The Visceral Adiposity Index, Lipid Accumulation Product, And Plasma Atherogenicindex Are Associated With Subclinical Atherosclerosis In Patients With Newly Diagnosedacromegaly, Mustafa Özbek, Murat Çalapkulu, Sema Hepşen, Muhammed Erkam Sencar, Hayri̇ Bostan, İlknur Öztürk Ünsal, Erman Çakal Jan 2021

The Visceral Adiposity Index, Lipid Accumulation Product, And Plasma Atherogenicindex Are Associated With Subclinical Atherosclerosis In Patients With Newly Diagnosedacromegaly, Mustafa Özbek, Murat Çalapkulu, Sema Hepşen, Muhammed Erkam Sencar, Hayri̇ Bostan, İlknur Öztürk Ünsal, Erman Çakal

Turkish Journal of Medical Sciences

Background /aim: Acromegaly is a rare chronic endocrine disorder, the active form of which is associated with an increased risk of cardiovascular and metabolic disease. Therefore, early diagnosis and treatment of cardiovascular diseases in acromegaly patients are important in terms of morbidity and mortality. The aim of this study was to determine whether the visceral adiposity index (VAI), lipid accumulation product (LAP), and plasma atherogenic index (PAI) are early cardiovascular risk markers in patients with active acromegaly. Materials and methods: The study included 45 patients newly diagnosed with acromegaly and 45 age-sex matched healthy control subjects. The VAI, LAP, and …

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Exercise Capacity, Muscle Strength, Dyspnea, Physical Activity, And Quality Of Life Inpreoperative Patients With Lung Cancer, Gülşah Barği, Ece Baytok, Zeli̇ha Çeli̇k, Merve Şatir Türk, Ali̇ Çeli̇k, İsmai̇l Cüneyt Kurul, Meral Boşnak Güçlü Jan 2021

Exercise Capacity, Muscle Strength, Dyspnea, Physical Activity, And Quality Of Life Inpreoperative Patients With Lung Cancer, Gülşah Barği, Ece Baytok, Zeli̇ha Çeli̇k, Merve Şatir Türk, Ali̇ Çeli̇k, İsmai̇l Cüneyt Kurul, Meral Boşnak Güçlü

Turkish Journal of Medical Sciences

Background/aim: To detect the extent to which physical impairments are observed in patients with lung cancer awaiting lung surgery, exercise capacity, muscle strength, physical activity, dyspnea, and quality of life (QOL) were objectively compared between the patients and healthy individuals in current study. Materials and methods: Patients with lung cancer (n = 26) and healthy individuals (n = 21) were included. Exercise capacity, respiratory (maximal inspiratory pressure (MIP), maximal expiratory pressure (MEP)) and quadriceps femoris muscle strength, physical activity, dyspnea and QOL were evaluated using 6-min walk test (6-MWT), a mouth pressure device, a hand-held dynamometer, a metabolic holter device, …

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The Effect Of Popliteal Sciatic Nerve Block With Methylprednisolone In The Management Ofpostinjection Sciatic Neuropathy After Clinical And Electrophysiological Examination, Damla Yürük, Ayçi̇n Yildiz Tabakoğlu Jan 2021

The Effect Of Popliteal Sciatic Nerve Block With Methylprednisolone In The Management Ofpostinjection Sciatic Neuropathy After Clinical And Electrophysiological Examination, Damla Yürük, Ayçi̇n Yildiz Tabakoğlu

Turkish Journal of Medical Sciences

Background/aim: This study aimed to investigate the effects of popliteal sciatic nerve block (PSNB) in the treatment of postinjection sciatic neuropathy (PISN) resistant to conservative treatments. Materials and methods: Patients diagnosed with PISN were included in the study. A damaged branch of the sciatic nerve was detected after neurological and electrophysiologic studies (EPSs). Visual analogue scale (VAS) was administered before, one hour after, and one month after the procedure. Also Leeds Assessment of Neuropathic Symptoms and Signs pain scale (LANSS) was administered before and one month after the procedure. The effects of EPSs findings and loss of muscle strength on …

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High Mobility Group Box-1 Levels May Be Associated With Disease Activity Of Behcet's Disease, Di̇lara Dönmez Güler, Ayşe Bahar Keleşoğlu Di̇nçer, Zeynep Ceren Karahan, Hasan Seli̇m Güler, Müçteba Enes Yayla, Serdar Sezer, Emi̇ne Gözde Aydemi̇r Gülöksüz, İlyas Ercan Okatan, Murat Torğutalp, Di̇dem Şahi̇n Eroğlu, Mehmet Levent Yüksel, Tahsi̇n Murat Turğay, Gülay Kinikli, Aşkin Ateş Jan 2021

High Mobility Group Box-1 Levels May Be Associated With Disease Activity Of Behcet's Disease, Di̇lara Dönmez Güler, Ayşe Bahar Keleşoğlu Di̇nçer, Zeynep Ceren Karahan, Hasan Seli̇m Güler, Müçteba Enes Yayla, Serdar Sezer, Emi̇ne Gözde Aydemi̇r Gülöksüz, İlyas Ercan Okatan, Murat Torğutalp, Di̇dem Şahi̇n Eroğlu, Mehmet Levent Yüksel, Tahsi̇n Murat Turğay, Gülay Kinikli, Aşkin Ateş

Turkish Journal of Medical Sciences

Background/aim: High mobility group box- 1 (HMGB- 1) is a nuclear protein acting as a proinflammatory molecule. The serum HMGB- 1 levels were found elevated in chronic inflammatory diseases. In this cross-sectional study, serum HMGB- 1 levels in Behcet's disease (BD) patients and healthy controls (HC) were studied. Also, its association with disease activity scores and clinical findings were evaluated. Materials and methods: Ninety BD patients and 50 age-sex matched HC were included in the study. Disease activity scores were assessed by Behcet Disease Current Activity Form (BDCAF) and Behcet Syndrome Activity Score (BSAS). Serum HMGB- 1 levels were measured …

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Pretreatment Serum Uric Acid Level Is Not A Surrogate Marker For The Outcome Offavipiravir Treatment In Covid-19 Patients, Ahmet Çağkan İnkaya, Emre Kara, Nursel Çalik Başaran, Taha Koray Şahi̇n, Oğuz Abdullah Uyaroğlu, Ömrüm Uzun, Serhat Ünal Jan 2021

Pretreatment Serum Uric Acid Level Is Not A Surrogate Marker For The Outcome Offavipiravir Treatment In Covid-19 Patients, Ahmet Çağkan İnkaya, Emre Kara, Nursel Çalik Başaran, Taha Koray Şahi̇n, Oğuz Abdullah Uyaroğlu, Ömrüm Uzun, Serhat Ünal

Turkish Journal of Medical Sciences

No abstract provided.

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Impact Of Low Molecular Weight Heparin Administration On The Clinical Course Of Thecovid-19 Disease, Burcu Yormaz, Di̇lek Ergün, Baykal Tülek, Recai̇ Ergün, Uğur Arslan, Fi̇kret Kanat Jan 2021

Impact Of Low Molecular Weight Heparin Administration On The Clinical Course Of Thecovid-19 Disease, Burcu Yormaz, Di̇lek Ergün, Baykal Tülek, Recai̇ Ergün, Uğur Arslan, Fi̇kret Kanat

Turkish Journal of Medical Sciences

Background: Lymphopenia is the most important criterion of mortality and discharging feature for patients infected with coronavirus disease 2019 (COVID-19). This study aimed to investigate the clinical impact of a low molecular weight heparin (LMWH) treatment on the clinical course of COVID-19. Materials and methods: Patients' clinical symptoms, radiologic outcomes, hematologic, biochemical, D-dimer, and C-reactive protein (CRP) results were obtained from their medical records. Participants were separated into 2 groups: one was treated with LMWH and the other was not. Improvement in the patients was compared before and after treatment. Results: Ninety-six patients who were diagnosed with COVID-19 between April …

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The Effect Of Comorbidity On Mortality In Elderly Patients Undergoing Emergencyabdominal Surgery: A Systematic Review And Metaanalysis, Fadi̇me Çinar, Göknur Parlak, Fatma Eti̇ Aslan Jan 2021

The Effect Of Comorbidity On Mortality In Elderly Patients Undergoing Emergencyabdominal Surgery: A Systematic Review And Metaanalysis, Fadi̇me Çinar, Göknur Parlak, Fatma Eti̇ Aslan

Turkish Journal of Medical Sciences

Background/aim: With the increase in the elderly population, the elderly proportion needing emergency surgery is also increasing. Despite medical advances in surgery and anesthesia, negative postoperative outcomes and high mortality rates are still present in elderly patients undergoing emergency surgery. Comorbidities are described as the main determining factors in poor outcomes. In this metaanalysis, it was aimed to investigate the effect of comorbidity on mortality in elderly patients undergoing emergency abdominal surgery. Materials and methods: The studies published between 2010-2019 were scanned from databases of Google Scholar, Cinahl, Pub Med, Medline and Web of Science. Quality criteria proposed by Polit …

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Placement Of Hemodialysis Catheters With The Help Of The Micropuncture Technique Inpatients With Central Venous Occlusion And Limited Access, Erdem Bi̇rgi̇, Hasanali̇ Durmaz Jan 2021

Placement Of Hemodialysis Catheters With The Help Of The Micropuncture Technique Inpatients With Central Venous Occlusion And Limited Access, Erdem Bi̇rgi̇, Hasanali̇ Durmaz

Turkish Journal of Medical Sciences

Background/aim: This study aims to describe the technical success of the micropuncture technique, which is performed in placement of tunneled hemodialysis catheters in patients with central venous occlusion and limited access. Materials and methods: A total of 25 patients with central venous occlusion and in need of catheter placement for hemodialysis between 2012 and 2018 were included in this study and analyzed retrospectively. Technical success was defined as the placement of tunneled dialysis catheters with optimal position and function. Results: Internal jugular vein access in 16 patients (14 right and 2 left) and right subclavian vein access in 3 patients …

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