Medicine and Health Sciences Commons^™

Low-Grade Primary Splenic Cd10-Positive Small B-Cell Lymphoma/Follicular Lymphoma, Rami Abdulbaki, Parastou Tizro, Victor E. Nava, Maria Gomes Da Silva, Joao L. Ascensao

Pathology Faculty Publications

No abstract provided.

Social Norms Change And Tobacco Use: A Protocol For A Systematic Review And Meta-Analysis Of Interventions., Shaon Lahiri, Jeffrey B. Bingenheimer, William Douglas Evans, Yan Wang, Priyanka Dubey, Bobbi Snowden

Prevention and Community Health Faculty Publications

No abstract provided.

Moerv29 Promotes Apoplastic Effector Secretion Contributing To Virulence Of The Rice Blast Fungus Magnaporthe Oryzae, Bin Qian, Xiaotong Su, Ziyuan Ye, Xinyu Liu, Muxing Liu, Danyu Shen, Han Chen, Haifeng Zhang, Ping Wang, Zhengguang Zhang

School of Medicine Faculty Publications

During plant-pathogenic fungi and host plants interactions, numerous pathogen-derived proteins are secreted resulting in the activation of the unfolded protein response (UPR) pathway. For efficient trafficking of secretory proteins, including those important in disease progression, the cytoplasmic coat protein complex II (COPII) exhibits a multifunctional role whose elucidation remains limited. Here, we discovered that the COPII cargo receptor MoErv29 functions as a target of MoHac1, a previously identified transcription factor of the UPR pathway. In Magnaporthe oryzae, deletion of MoERV29 severely affected the vegetative growth, conidiation and biotrophic invasion of the fungus in susceptible rice hosts. We demonstrated that MoErv29 …

Association Between Diet Quality Indices And Incidence Of Type 2 Diabetes In The Melbourne Collaborative Cohort Study, Allison M. Hodge, Md Nazmul Karim, James Hébert Scd, Nitin Shivappa Mbbs, Mph, Ph.D., Barbora De Courten

Faculty Publications

Type 2 diabetes mellitus is a common condition whose incidence is increasing worldwide, and for which obesity and diet are important risk factors. The aim of this study was to assess the association of three diet quality scores with diabetes risk and how much of the association was mediated through body size. The Melbourne Collaborative Cohort Study recruited 41,513 men and women aged 40–69 years during 1990–1994. At baseline, data were collected on lifestyle and diet, anthropometric measures were performed. Incident diabetes was assessed by self-report at follow-up surveys in 1994–1998 and 2003–2007. The associations between the dietary inflammatory index …

Perspectives Of Black And Hispanic Children Living In Under-Resourced Communities On Meal Preparation And Grocery Shopping Behaviors: Implications For Nutrition Education, Chishinga Callender, Denisse Velazquez, Meheret Adera, Jayna M Dave, Norma Olvera, Tzuan A Chen, Shana Alford, Debbe Thompson

Children’s Nutrition Research Center Staff Publications

Minority children living in under-resourced communities are at the greatest risk for obesity and poor diet quality. Child involvement in meal preparation may be a helpful strategy to improve diet quality. This paper explores minority children's perspectives regarding this. Eighteen children participated in a mixed methods study (online surveys, telephone interviews). Descriptive statistics were calculated for child demographic and psychosocial factors. Thematic analysis was used to code and analyze the interviews. Most children reported having cooking experience (83%) and cooking with family (94%) and exhibited high cooking self-efficacy (21.8 ± 2.9) and positive cooking attitudes (25.7 ± 4.4). Children reported …

Septic Pulmonary Embolism Causing Recurrent Pneumothorax In An Intravenous Drug User Without Right-Sided Valvular Vegetation In Infective Endocarditis, Mason Montano, Kevin Lee, Kushal Patel, Mutsumi Kioka

Department of Internal Medicine Faculty Research

The following report illustrates a case of a 36-year-old Caucasian male with intravenous drug use (IVDU) induced septic thrombophlebitis presenting with recurrent unilateral pneumothoraces from septic pulmonary embolism (SPE) without the presence of obvious right-sided valvular vegetation in infective endocarditis (IE), defined as tricuspid or pulmonary valve lesions. Pneumothorax (PTX) has been observed as a rare complication of SPE and is commonly associated with infective right-sided IE, IVDU, and intravascular indwelling catheters. However, this case is novel as it is the very rare documented case of recurrent, unilateral, spontaneous right PTX refractory to multiple chest tube placements in such a …

Construct Validity For The Self-Reported Competency And Sub-Construct Associated Characteristics Of Romanian Physicians In Autism Spectrum Disorder, Mohammad H Rahbar, Iuliana Dobrescu, Shezeen Gillani, Manouchehr Hessabi, Sori Kim, Mihaela Stancu, Florina Rad

Faculty, Staff and Student Publications

BACKGROUND: Lack of physicians' knowledge regarding mental health, including Autism Spectrum Disorder (ASD) could have adverse effects on affected individuals' health and quality of life. The purpose of this study was to provide construct validity for a modified questionnaire in order to determine the self-reported competency for underlying sub-constructs in ASD, make inferences on perceived competence in ASD based on a sample of Romanian physicians, and identify physicians' characteristics associated with these sub-domains of competency.

METHODS: For this survey, we modified a questionnaire that was used in Pakistan and Turkey, and administered it to a sample of 383 practicing physicians …

China’S Strategies For Governance Of Biotechnological Changes And New Ethical Challenges, Yaojin Peng, Zhou Qi

Bulletin of Chinese Academy of Sciences (Chinese Version)

Biotechnology is changing greatly over recent years, providing huge benefits to human society. However, the ethics, safety, and negative externalities of biotechnology have become increasingly prominent. Currently, biotechnology is still in the early stage of development, and full of high uncertainty. Technological changes in this field have the characteristics of stronger subversiveness, complexity, and social relevance. The world is facing a process of great development of biotechnology, new outbreaks of ethical challenges, and ethical governance reforms. China should take this opportunity to promote the high-quality development of biotechnology on the one hand, and on the other hand, adopt a multi-pronged …

Overcoming The Covid-19 Pandemic For Dementia Research: Engaging Rural, Older, Racially And Ethnically Diverse Church Attendees In Remote Recruitment, Intervention And Assessment, Lisa Kirk Wiese, Ishan C. Williams, Nancy E. Schoenberg, James E. Galvin, Jennifer Lingler

Behavioral Science Faculty Publications

Background: Access to cognitive screening in rural underserved communities is limited and was further diminished during the COVID-19 pandemic. We examined whether a telephone-based cognitive screening intervention would be effective in increasing ADRD knowledge, detecting the need for further cognitive evaluation, and making and tracking the results of referrals.

Method: Using a dependent t-test design, older, largely African American and Afro-Caribbean participants completed a brief educational intervention, pre/post AD knowledge measure, and cognitive screening.

Results: Sixty of 85 eligible individuals consented. Seventy-percent of the sample self-reported as African American, Haitian Creole, or Hispanic, and 75% were female, with an average …

Low-Dose Dobutamine Cardiovascular Magnetic Resonance Segmental Strain Study Of Early Phase Of Intramyocardial Hemorrhage Rats, Rui Xia, Bo He, Tong Zhu, Yu Zhang, Yushu Chen, Lei Wang, Yang Zhou, Jichun Liao, Jie Zheng, Yongmei Li, Fajin Lv, Fabao Gao

2020-Current year OA Pubs

BACKGROUND: This study investigates the segmental myocardial strain of the early phase of intramyocardial hemorrhage (IMH) caused by reperfused myocardial infarction (MI) in rats by low-dose dobutamine (LDD) cardiovascular magnetic resonance (CMR) feature-tracking.

METHODS: Nine sham rats and nine rats with 60-min myocardial ischemia followed by 48-h reperfusion were investigated using CMR, including T2*-mapping sequence and fast imaging with steady-state precession (FISP)-cine sequence. Another FISP-cine sequence was acquired after 2 min of dobutamine injection; the MI, IMH, and Non-MI (NMI) areas were identified. The values of peak radial strains (PRS) and peak circumferential strains (PCS) of the MI, IMH and …

Critical Pedagogy In The Time Of Covid-19: Lessons Learned, Carol Christine Hordatt Gentles

Journal of Multicultural Affairs

The abrupt closure of universities due to the coronavirus pandemic caused unprecedented challenges for educators. They struggled to transition to online teaching almost overnight. This has raised questions about the readiness of Higher Education for digitalisation and hybridization of learning environments and focused attention on the renewal of teaching and learning models. It is incumbent upon those who practise critical pedagogy to join this conversation; the mandatory transition has raised difficult questions around how to ensure continuity of an agenda to offer students humanistic and democratic learning experiences in the new virtual reality. In this paper I offer a critical …

Book Review: The Death Project: An Anthology For These Times, Ted D. Ayres

Journal of Multicultural Affairs

A book review of The Death Project: An Anthology for These Times.

Ted Ayres, Social Justice And Education Advocate: "Making It Count" With Book Reviews, Kristen P. Erdem

Journal of Multicultural Affairs

This is an interview article with a prolific reviewer of books seen on public television and in print. Ted Ayres had an inspired legal career, and his advocacy continues to this day. The year 2020, like no other year in our recent U.S. history, was a raucous reckoning for an array of social justice issues. As this theme continues in 2021, it is heartwarming getting to know a quiet advocate in our midst. Meet Ted Ayres. Ayres will be a contributor to the journal with book reviews. This is an introduction to the person, Ted Ayres as social justice and …

How The Common School Has Failed Hispanic Children—Witnessing The Severe Regression Of Language English Proficient Learners During A Pandemic: Teaching During Covid-19, Yvonne S. Herrera

Journal of Multicultural Affairs

Personal reflection on the impacts of the common school on Hispanic children during the COVID-19 pandemic, when Hispanic children experienced less opportunities in becoming educated due to lack of accessible technology.

Overview: From The Desk Of The Guest Editor, Tonya Huber

Journal of Multicultural Affairs

Overview from the Guest Editor on this special issue on the impacts of Covid-19 in educational settings. One theme explored in the contents of this issue is the powerlessness many educators felt as the editors set out to hear, comprehend, represent, and amplify their experiences. Other themes include: appreciation and empathy, focusing on what matters, and new ways of teaching with technology.

Means Of Training And Monitoring And Methods Of Endurance Development Of Female Handball Players, Shoislom Kallibaevich Pavlov

Eurasian Journal of Sport Science

Purpose: Development and control of endurance of handball players by studying modern innovative tools and methods of endurance development, as well as improving the effectiveness of endurance training.

Methods: The following techniques are used to train endurance: The technique of evenly performed exercises is used in the training of general endurance. This method is used during training to prepare for maximum continuous training, which is performed regularly with a pulse of no more than 130 beats per minute. In most cases, recovery performed in an evenly executed exercise style can be considered insufficient. Alternating exercise styles are used to improve …

The Practice Of Conducting A High-Intensity Weekly Micro Cycle At The Stage Of Pre-Competitive Training Of Young Gymnasts, Djamshid Khasanovich Umarov

Eurasian Journal of Sport Science

Purpose: In this article, the issues of searching for the rational construction of the educational and training process of young gymnasts and the effective ratio of loads of different directions at the stage of in-depth specialization in the pre-competitive micro cycle are considered. To study the expediency of using high-intensity training loads in the process of training young gymnasts aged 12-16 years.

Methods: Study and analysis of literary sources on the research topic, pedagogical observation, pedagogical testing, pedagogical experiment, static methods of processing results.

Results: The number of combinations for gymnasts of all ages varies within the planned range (see …

Planning The Annual Training Cycle Of Football Students Of Sports Improvement Groups, Timur Shamshetovich Seitmuratov

Eurasian Journal of Sport Science

Purpose: The aim of the study is the substantiation and testing of the methodology of planning the training of football students of sports improvement groups in the one-year cycle.

Methods: The study used the analysis of scientific and methodological literature, questionnaires, testing, pedagogical experiment, methods of mathematical statistics.

Results: The content of general and special physical training of football players of sports improvement groups has been studied, as a result of which the most significant components of physical preparedness have been identified. The planning method of physical training process of football players of sports improvement groups in the annual cycle, …

Introduction To Systematic Reviews And Meta-Analysis, Joanna M. Burkhardt

Library Impact Statements

No abstract provided.

2021-11-19 Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

Contains the tables Statewide Hospital Capacity Report for COVID-19, COVID-19 Metrics, Statewide Hospital Available PPE Tracking for COVID-19, as well as the tables PPE Days On Hand and Patient Census.

2021-11-19_Michiganoverview_Covidvaccinestats, Michigan Department Of Health & Human Services

Michigan COVID-19 Vaccine Data

The COVID Vaccine Dashboard page was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus/0,9753,7-406-98178_103214-547150--,00.html.

First-dose tracker above is for age 16+. Coverage maps below are for age 5+.

Previously reported numbers of administered vaccine doses may change as new data are received. A possible lag in reporting vaccine doses will result in increases in numbers previously reported.

This report is created by the Michigan Department of Health and Human Services Division of Immunization from data reported to the Michigan Care Improvement Registry (MCIR).

The dashboard contained the tabs Vaccines Delivered, Delivery Trend, Primary Series Doses Administered, Primary …

Pre-Existing Cardiovascular Disease Increases Risk Of Atrial Arrhythmia And Mortality In Cancer Patients Treated With Ibrutinib, Juan Carlo Avalon, Jacob Fuqua, Tyler Miller, Seth Deskins, Chelby Wakefield, Austin King, Sonya Inderbitzin-Brooks, Christopher Bianco, Lauren Veltri, Wei Fang, Michael Craig, Abraham Kanate, Kelly Ross, Midhun Malla, Brijesh Patel

Faculty & Staff Scholarship

Background

Ibrutinib is a Bruton’s tyrosine kinase inhibitor used in the treatment of hematological malignancies. The most common cardiotoxicity associated with ibrutinib is atrial arrhythmia (atrial fibrillation and flutter). It is known that patients with cardiovascular disease (CVD) are at an increased risk for developing atrial arrhythmia. However, the rate of atrial arrhythmia in patients with pre-existing CVD treated with ibrutinib is unknown.

Objective

This study examined whether patients with pre-existing CVD are at a higher risk for developing atrial arrhythmias compared to those without prior CVD.

Methods

A single-institution retrospective chart review of patients with no prior history of …

2021-11-19_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled. COVID case and testing data will be posted three times a week on Mondays, Wednesdays and Fridays.

This report is provisional and subject to change. City of Detroit and Wayne County are reported separately. MDHHS began tracking probable cases April 5, 2020. FCI indicates federal correctional institute. MDOC indicates Michigan Department of Corrections. Diagnostic tests, including nucleic acid amplification/real-time …

Evaluation Of Lifestyle Modification Program For Polycystic Ovary Syndrome In Infertile Women, Kelly Batton

Dissertations

Abstract

Problem: Polycystic Ovary Syndrome (PCOS) affects a large proportion of the female population worldwide. PCOS can have a wide variety of health implications for the woman including difficulty achieving pregnancy.

Methods: A retrospective chart review of 368 patient records were assessed for inclusion criteria yielding 163 patients with PCOS suffering from infertility. Demographic and health data were gathered for each patient to provide a baseline comparison between the first two quarters of 2019 and the first two quarters of 2020.

Results: The results of the study were mixed. Patients who lost weight did have a higher positive pregnancy rate. …

2021-11-19_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated three times a week on Mondays, Wednesdays and Fridays.

Syndromic Surveillance System data is obtained from approximately 216 facilities participating in syndromic surveillance (139 Emergency Departments (ED), 77 Urgent Care) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, …

Selection Shapes The Landscape Of Functional Variation In Wild House Mice., Raman Akinyanju Lawal, Uma P Arora, Beth L Dumont

Faculty Research 2021

BACKGROUND: Through human-aided dispersal over the last ~ 10,000 years, house mice (Mus musculus) have recently colonized diverse habitats across the globe, promoting the emergence of new traits that confer adaptive advantages in distinct environments. Despite their status as the premier mammalian model system, the impact of this demographic and selective history on the global patterning of disease-relevant trait variation in wild mouse populations is poorly understood.

RESULTS: Here, we leveraged 154 whole-genome sequences from diverse wild house mouse populations to survey the geographic organization of functional variation and systematically identify signals of positive selection. We show that a significant …

2021-11-19_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …

The Effects Of Covid-19 On The Service Delivery Of Speech And Language Therapy: A Literature Review, Hanna Hill

Honors College Theses

The purpose of this thesis was to investigate the effects of the novel coronavirus disease 2019 (COVID-19) pandemic on the service delivery of speech and language therapy services in schools, early intervention, and outpatient settings. This analysis examined various service delivery settings in the realm of speech-language therapy that were affected by COVID-19. Per guidance of the Centers for Disease Control and Prevention (CDC), worldwide governing legislatures, and American Speech-Language-Hearing Association (ASHA), many measures were put into place throughout the spread of COVID-19. Quarantine, the use of various protective tools, and social distancing interrupted face-to-face services that are essential to …

Spatial Distribution Of Pm2.5-Related Premature Mortality In China, Sheng Zheng, Uwe Schlink, Kin-Fai Ho, Ramesh P. Singh, Andrea Pozzer

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

PM_2.5 is a major component of air pollution in China and has a serious threat to public health. It is very important to quantify spatial characteristics of the health effects caused by outdoor PM_2.5 exposure. This study analyzed the spatial distribution of PM_2.5 concentration (45.9 μg/m³ national average in 2016) and premature mortality attributed to PM_2.5 in cities at the prefectural level and above in China in 2016. Using the Global Exposure Mortality Model (GEMM), the total premature mortality in China was estimated to be 1.55 million persons, and the per capita mortality was 11.2 …

Attitudes Toward Osteopathic Medicine Scale: Development And Psychometrics, Mohammadreza Hojat Professor, Jennifer Desantis, Robert A Cain, Mark R Speicher, Lynn Bragan, Leonard H Calabrese

Department of Medicine Faculty Papers

Objective: To develop a valid and reliable instrument for measuring attitudes toward osteopathic medicine.

Methods: Participants included 5,669 first-year students from 33 U.S. colleges of osteopathic medicine, who completed an online survey at the beginning of the 2019-2020 academic year. Using data from the nationwide Project in Osteopathic Medical Education and Empathy, we developed a 13-item instrument: Attitudes Toward Osteopathic Medicine Scale (ATOMS) and demonstrated the validity and reliability of its scores. The social desirability response bias was controlled in statistical analyses.

Results: The corrected item-total score correlations were all positive and statistically significant, and the effect sizes of item …