Medicine and Health Sciences Commons^™

Mental Health Disparities In Social Work Practice Of Minority Youth Offenders, Beverly Ann Rivera

Walden Dissertations and Doctoral Studies

AbstractA large number of minority youths placed in the juvenile justice system across the United States have mental health disorders. Most of these youths do not receive mental health services or support within the system, which increases risk factors such as undiagnosed and untreated mental illness and adverse outcomes such as recidivism. This action research sought to uncover whether mental health disparities in social work practice in the juvenile justice system were due to race and ethnicity and asked social workers to recommend strategies to improve mental health availability, access, and provision. Participants in the study were social workers who …

Predictors Of Depression Screening Among Cancer Patients In U.S. Ambulatory Settings, Joseph Oluyinka Fawole

Walden Dissertations and Doctoral Studies

Depression is a common mental health comorbidity in cancer diagnoses, affecting 8-24% of cancer patients. Despite the high prevalence of depression among cancer patients, it is often unrecognized and untreated, thereby representing an enormous psychological distress source among the cancer patient population. The purpose of this study was to explore and establish the factors that predict depression screening among cancer patients in the ambulatory care setting in the United States. The health belief model guided the study. Secondary data from the National Ambulatory Medical Care Survey were analyzed to evaluate the predictors of depression screening in patients diagnosed with cancer. …

Educating Clinicians In A Nursing Facility To Proactively Manage Urinary Tract Infections, Setha Joseph

Walden Dissertations and Doctoral Studies

AbstractUrinary tract infections (UTIs) have been identified as the most common reason for hospital visits among adults. The Centers for Disease Control and Prevention indicates that the prevalence of UTIs in long-term care facilities ranges from 20%-50%. The purpose of this staff education project was to implement an educational program to increase staff knowledge of proactive management of urinary tract health with the ultimate goal of reducing acute illnesses at the skilled nursing facility (SNF). Knowles theory of adult learning informed curriculum development and Kirkpatrick's levels of training evaluation guided program evaluation. The project team planned, developed, implemented, and evaluated …

Site-Search Process For Synaptic Protein-Dna Complexes, Sridhar Vemulapalli, Mohtadin Hashemi, Yuri L. Lyubchenko

Journal Articles: Pharmaceutical Sciences

The assembly of synaptic protein-DNA complexes by specialized proteins is critical for bringing together two distant sites within a DNA molecule or bridging two DNA molecules. The assembly of such synaptosomes is needed in numerous genetic processes requiring the interactions of two or more sites. The molecular mechanisms by which the protein brings the sites together, enabling the assembly of synaptosomes, remain unknown. Such proteins can utilize sliding, jumping, and segmental transfer pathways proposed for the single-site search process, but none of these pathways explains how the synaptosome assembles. Here we used restriction enzyme SfiI, that requires the assembly of …

Sex-Specific Gene Expression In Flupirtine-Treated Cln3Δex7/8 Mouse Brain, Joelle Makoukji, Sara Saab, Katia Maalouf, Nadine J. Makhoul, Angelica V. Carmona, Nihar Kinarivala, Paul C. Trippier, Rose-Mary Boustany

Journal Articles: Pharmaceutical Sciences

Gene expression is a powerful tool to understand structure-function relationships in the nervous system. This study reports global gene expression changes induced by flupirtine in brain of male and female Cln3Δex7/8 mice, exposing potential flupirtine targets at the molecular level. Gene expression analysis of male and female Cln3Δex7/8 mouse brain was determined following oral administration of flupirtine for 14 weeks, using Mouse Genome 430 2.0 array Chips and an Affymetrix platform. Fifty-six genes in males and 79 in females were differentially expressed in flupirtine- versus vehicle-treated Cln3Δex7/8 mouse brain. Flupirtine altered several pathways in Cln3Δex7/8 mouse brain: apoptosis, the complement …

Cd4+ Effector T Cells Accelerate Alzheimer's Disease In Mice, Jatin Machhi, Pravin Yeapuri, Yaman Lu, Emma Foster, Rupesh Chikhale, Jonathan Herskovitz, Krista L. Namminga, Katherine E. Olson, Mai Mohamed Abdelmoaty, Ju Gao, Rolen M. Quadros, Tomomi Kiyota, Liang Jingjing, Bhavesh D. Kevadiya, Xinglong Wang, Yutong Liu, Larisa Y. Poluektova, Channabasavaiah B. Gurumurthy, R. Lee Mosley, Howard Gendelman

Journal Articles: Pharmacology & Experimental Neuroscience

BACKGROUND: Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by pathological deposition of misfolded self-protein amyloid beta (Aβ) which in kind facilitates tau aggregation and neurodegeneration. Neuroinflammation is accepted as a key disease driver caused by innate microglia activation. Recently, adaptive immune alterations have been uncovered that begin early and persist throughout the disease. How these occur and whether they can be harnessed to halt disease progress is unclear. We propose that self-antigens would induct autoreactive effector T cells (Teffs) that drive pro-inflammatory and neurodestructive immunity leading to cognitive impairments. Here, we investigated the role of effector immunity and …

Child Health And The Implementation Of Community And District-Management Empowerment For Scale-Up (Codes) In Uganda: A Randomised Controlled Trial, Peter Waiswa, Flavia Mpanga, Danstan Bagenda, Rornald Muhumuza Kananura, Thomas O'Connell, Dorcus Kiwanuka Henriksson, Theresa Diaz, Florence Ayebare, Anne Ruhweza Katahoire, Eric Ssegujja, Anthony Mbonye, Stefan Swartling Peterson

Journal Articles: Anesthesiology

INTRODUCTION: Uganda's district-level administrative units buttress the public healthcare system. In many districts, however, local capacity is incommensurate with that required to plan and implement quality health interventions. This study investigates how a district management strategy informed by local data and community dialogue influences health services.

METHODS: A 3-year randomised controlled trial (RCT) comprised of 16 Ugandan districts tested a management approach, Community and District-management Empowerment for Scale-up (CODES). Eight districts were randomly selected for each of the intervention and comparison areas. The approach relies on a customised set of data-driven diagnostic tools to identify and resolve health system bottlenecks. …

A Holistic Systems Approach To Characterize The Impact Of Pre- And Post-Natal Oxycodone Exposure On Neurodevelopment And Behavior, Katherine E. Odegaard, Victoria L. Schaal, Alexander R. Clark, Sneh Koul, Jagadesan Sankarasubramanian, Zhiqiu Xia, Melissa Mellon, Mariano Uberti, Yutong Liu, Andrew Stothert, Matthew J. Van Hook, Han-Jun Wang, Chittibabu Guda, Steven J. Lisco, Gurudutt Pendyala, Sowmya V. Yelamanchili

Journal Articles: Anesthesiology

Background: Increased risk of oxycodone (oxy) dependency during pregnancy has been associated with altered behaviors and cognitive deficits in exposed offspring. However, a significant knowledge gap remains regarding the effect of in utero and postnatal exposure on neurodevelopment and subsequent behavioral outcomes. Methods: Using a preclinical rodent model that mimics oxy exposure in utero (IUO) and postnatally (PNO), we employed an integrative holistic systems biology approach encompassing proton magnetic resonance spectroscopy (¹H-MRS), electrophysiology, RNA-sequencing, and Von Frey pain testing to elucidate molecular and behavioral changes in the exposed offspring during early neurodevelopment as well as adulthood. Results: ^{1 …}

Crosstalk Between Staphylococcus Aureus And Innate Immunity: Focus On Immunometabolism, Christopher M. Horn, Tammy Kielian

Journal Articles: Pathology and Microbiology

Staphylococcus aureus is a leading cause of bacterial infections globally in both healthcare and community settings. The success of this bacterium is the product of an expansive repertoire of virulence factors in combination with acquired antibiotic resistance and propensity for biofilm formation. S. aureus leverages these factors to adapt to and subvert the host immune response. With the burgeoning field of immunometabolism, it has become clear that the metabolic program of leukocytes dictates their inflammatory status and overall effectiveness in clearing an infection. The metabolic flexibility of S. aureus offers an inherent means by which the pathogen could manipulate the …

Machine Learning To Predict Sports-Related Concussion Recovery Using Clinical Data, Yan Chu, Gregory Knell, Riley P. Brayton, Scott O. Burkhart, Xiaoqian Jiang, Shayan Shams

Faculty Publications - Doctor of Psychology (PsyD) Program

Objectives: Sport-related concussions (SRCs) are a concern for high school athletes. Understanding factors contributing to SRC recovery time may improve clinical management. However, the complexity of the many clinical measures of concussion data precludes many traditional methods. This study aimed to answer the question, what is the utility of modeling clinical concussion data using machine-learning algorithms for pre- dicting SRC recovery time and protracted recovery? Methods: This was a retrospective case series of participants aged 8 to 18 years with a diagnosis of SRC. A 6- part measure was administered to assess pre-injury risk factors, initial injury severity, and post-concussion …

The Impact Of Introducing Ambulance And Delivery Fees In A Rural Hospital In Tanzania, Corinna Vossius, Estomih Mduma, Robert Moshiro, Paschal Mdoe, Jan Terje Kvaløy, Hussein Kidanto, Sara Lyanga, Hege Ersdal

Faculty of Health Sciences, East Africa

Background Access to health care facilities is a key requirement to enhance safety for mothers and newborns during labour and delivery. Haydom Lutheran Hospital (HLH) is a regional hospital in rural Tanzania with a catchment area of about two million inhabitants. Up to June 2013 ambulance transport and delivery at HLH were free of charge, while a user fee for both services was introduced from January 2014. We aimed to explore the impact of introducing user fees on the population of women giving birth at HLH in order to document potentially unwanted consequences in the period after introduction of fees. …

Validation Of The Swahili Version Of The International Prostate Symptom Score At A Private, Nonprofit General Hospital In Dar Es Salaam, Tanzania, Miten Patel, Masawa Klint, Philip Adebayo, Authar Ali, Jasmit Shah, Ali Akbar Zehri

Faculty of Health Sciences, East Africa

Background:

Accuracy in translating the International Prostate Symptom Score (IPSS) into different languages is essential to ensure that it is comparable to the original version and acceptable to the target population. We aimed to develop and validate a Swahili version of the IPSS (sIPSS).

Methods:

We conducted a cross-sectional study involving 53 patients presenting with lower urinary tract symptoms to the Aga Khan Hospital in Dar es Salaam, Tanzania, from April through December 2018. We enrolled 53 patients with confirmed benign prostatic hypertrophy and 32 control patients with suspected or confirmed urolithiasis. We assessed the face validity and discriminative validity …

Carbon Dioxide And Particulate Matter Concentration On Hampton Roads Air Quality, Gregory Hubbard

OUR Journal: ODU Undergraduate Research Journal

Hampton Roads has been a maritime crossroads for the last 400 years. Industrialization has impacted the coastal region for the last 250 years. The expansion of the Port of Virginia in 2019 has created dense traffic in the region resulting in impacts to air quality. Two waste products that affect humans are particulate matter and carbon dioxide. Both respective emissions can cause adverse effects on humans, such as asthma, some lung cancers, and other respiratory distress. Scientists and health practitioners are studying the effects of particulate matter on human health. Hampton Roads, in particular, because of its unique location on …

Antibiotic Resistance In Manure- Amended Agricultural Soils, Maranatha Zelt, Zachary Staley, Xu Li, Bing Wang, Daniel N. Miller, Amy Schmidt

Nebraska Beef Cattle Reports

Manure application to agricultural land benefits soil health and agronomic yields. However, as antibiotic resistance becomes a more serious threat to public health, there is concern that antibiotic resistance originating from livestock manure could impact human health through contamination of the environment or food. This study sought to quantify this risk by monitoring concentrations of antibiotic resistance bacteria and genes in fallow soil during the period of October through April, representing fall manure application through spring planting. Resistance to three common antibiotics— tylosin, azithromycin and tetracycline— was monitored following application of fresh, stockpiled, or composted beef feedlot manure, or inorganic …

Employability Of The Doctor Of Athletic Training Degree Within Academe, Bonnie L. Van Lunen, Stephanie H. Clines, Tyler Reems, Lindsey E. Eberman, Dorice Ann Hankemeier, Cailee E. Welch Bacon

Athletic Training Faculty Publications

Context: The Doctor of Athletic Training (DAT) degree has recently been introduced into academe. Limited literature exists regarding how individuals with this degree can be utilized as athletic training faculty.

Objective: To identify department chairs' perceptions of the DAT degree and determine whether they view the degree as viable when hiring new faculty within a post-baccalaureate professional AT program.

Design: Cross-sectional survey design

Setting: Online survey instrument

Patients or Other Participants: 376 department chairs who had oversight of Commission on Accreditation of Athletic Training Education athletic training programs were invited to participate. 190 individuals (50.5%) accessed the survey and 151 …

Using Eye Tracking To Explore Visual Attention In Adolescents With Autism Spectrum Disorder, Anne M.P. Michalek, Jonna Bobzien, Victor A. Lugo, Chung Hao Chen, Ann Bruhn, Michail Giannakos

Communication Disorders & Special Education Faculty Publications

Video social stories are used to facilitate understanding of social situations for adolescents with autism spectrum disorder (ASD). This study explored the use of eye tracking technology to understand how adolescents with and without ASD visually attend to video social story content and whether visual attention is related to content comprehension. Six adolescents, with and without ASD, viewed a video social story of visiting a dental office. Eye gaze metrics, including fixation duration and count, and visit duration were collected to measure visual attention, and a knowledge assessment was administered for comprehension. Results indicated adolescents with ASD fixated and maintained …

Compliance Of Checking Hba1c In A Tertiary Care Hospital Of Pakistan, Abdul Aziz, Syed Ahsan Ali

Section of Diabetes, Endocrinology and Metabolism

Background and objectives: The prevalence of diabetes mellitus worldwide was 171 million one and half decade ago, while the prediction is 366 million patients by 2030 and more than 640 million people by 2040. HbA1c value represents average blood glucose over the past 2-3 months and accounts for both pre-prandial and post-prandial blood glucose levels. A link between HbA1c and diabetic complications has been confirmed. In general, patients with controlled diabetes mellitus should have at least biannual testing, while patients with uncontrolled diabetes mellitus or unmet glycemic targets should be tested every three months. The objective was to see compliance …

Detecting Anterior Cruciate Ligament Tears And Posterolateral Corner Injuries On Magnetic Resonance Imaging, Paul Woloszyn, Vishal Desai, Md, Simukayi Mutasa, Md, Tiffany D’Souza, Dominick Battistini, Sasha Mitts, Bryan Sadler

Phase 1

Introduction: Anterior Cruciate Ligament (ACL) tears are an extremely common orthopedic injury, with an incidence ranging from 39-52 per 100,000. Knee Magnetic Resonance Imaging (MRI) scans are the gold standard for diagnosing ACL tears and their comorbidities, such as posterolateral corner injuries; the results of these scans determine the appropriate treatment needed for patients. There is evidence that machine learning can be used to automate the detection of pathology on MRI, and we hypothesize that we can train a neural network machine learning model to accurately interpret ACL injuries and posterolateral corner injuries.

Methods: We will be analyzing over 1000 …

Creation Of A Web-Based Tool To Facilitate Community Connectivity, Andrew Zeiger, Victoria Gulick, Tejal U. Naik

Phase 1

Introduction: Although medical schools are implementing programs to promote student scholarship, few programs exist to informally promote inter-student collaboration. Considering many medical students are early in the process of deciding what they want to spend their lives pursuing, and high levels of social connection and engagement may reduce burnout, we sought to evaluate medical students’ attitudes about inter-student collaboration.

Methods: Approximately 1000 medical students in all classes at Sidney Kimmel Medical College (SKMC) were invited to complete a questionnaire. Data collection remains active. Survey questions included a rank order choice on how respondents would use a tool to learn about …

Nutrition Risk And Validation Of An Hiv Disease-Specific Nutrition Screening Tool In Ghana, Lauri Wright, Maxwell Bisala Konlan, Laurene Boateng, James B. Epps

Mental Health Law & Policy Faculty Publications

Objectives: The objectives of this study were to assess the nutritional status and the most commonly reported nutrition-related factors contributing to nutritional risk in people living with HIV/AIDS (PLWHA) in Ghana and the specificity and sensitivity of the Rapid Nutrition Screening for HIV disease tool (RNS-H) in this population.

Design: A cross-sectional design was utilised. Patients were screened for nutritional status during a one-week period by clinic nurses using the RNS-H. Results were compared with a comprehensive nutritional assessment by a dietitian.

Setting: The research was conducted in a public health clinic at the University of Ghana Hospital, Legon.

Subjects: …

Lumbopelvic Stability And Trunk Muscle Contractility Of Individuals With Chronic Ankle Instability, Ryan S. Mccann, Kelly Johnson, Ashley M.B. Suttmiller

Rehabilitation Sciences Faculty Publications

BACKGROUND: Chronic ankle instability (CAI) results in hip neuromuscular impairments that can perpetuate dysfunction through reduced lumbopelvic stability and subsequent malpositioning of the lower body during functional movement. Lumbopelvic stability might be further impaired through changes in trunk muscular contractility. However, lumbopelvic stability and trunk muscle morphology have not been compared between individuals with and without CAI.

PURPOSE: To compare lumbopelvic stability and trunk muscle contractility between individuals with and without chronic ankle instability (CAI) and determine if lumbopelvic stability and trunk muscle contractility are associated with self-reported function.

STUDY DESIGN: Case-control study.

METHODS: Ten individuals with CAI, 10 …

Maternal Proximity To Mountaintop Removal Mining And Birth Defects In Appalachian Kentucky, 1997-2003, Daniel B. Cooper

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Background: Extraction of coal through mountaintop removal mining (MTR) alters many dimensions of the landscape, and explosive blasts, exposed rock, and coal washing have the potential to pollute air and water with substances known to increase risk of developmental and birth anomalies. Previous research suggests that infants born to mothers living in MTR coal mining counties have higher prevalence of most types of birth defects.

Objectives: This study seeks to examine further the relationship between MTR activity and birth defects by employing individual level exposure estimation through precise satellite data of MTR activity in the Appalachian region and maternal residence …

Patient Engagement In Patient Portals In Appalachia Versus Surrounding Us Census Regions: An Analysis Of Hints (Health Information National Trends Survey) Data, 2017 - 2020, Heather Lea Tudor

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

OBJECTIVE: Those living in the Appalachian regions face more significant healthcare disparities than those in the US. Patient portals can decrease disparities and increase health outcomes and health literacy. The purpose of this study was to determine if those living in the Appalachian region were offered access to and used their patient portals differently than the surrounding US Census region. Additionally, we aimed to determine if there was a difference in reported reasons for non-use of patient portals.

METHODS: This was a descriptive study using data from the National Cancer Institute’s Health Information National Trends Survey (HINTS) data (2017-2020) to …

Racial Disparities In Syringe Exchange Program Access In Kentucky, Ankur Bhargava

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Non-white Kentuckians use syringe exchange programs (SEPs) at lower rates than white Kentuckians. This analysis begins by documenting this disparity and then explores several potential causes. Access to SEPs is limited by law as only health departments may operate them. Areas of the state in which SEPs face political opposition are therefore underserved. A consequence of this legal limitation is distance to a SEP may be a barrier to access. Analysis of publicly available data indicates non-white drug users in Kentucky are located closer to syringe exchange programs in urban areas but farther away in rural areas. Proximity to a …

The Witness Project In Whitehall, Oh, Freda Allyson Hucek

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Abstract

The Witness Project (WP) is an evidence-based breast cancer screening intervention that will be implemented in Whitehall, Ohio, at three different churches by the Franklin County Health Department. The WP will target African American women 50-74 years old who are non-compliant with current United States Preventative Services Task Force (USPSTF) breast cancer screening recommendations. African American women face disproportionately higher mortality rates from breast cancer when compared to other racial and ethnic groups in the United States and in Whitehall. African American women are less likely to discuss breast cancer and preventive screening services within their community. The WP …

When Disparities Become Deadly: Spatial Differences In Pm2.5 Levels Within The City Of Pomona, California, Pauline Bekkers

Pomona Senior Theses

This thesis discusses the disparities in particulate matter concentrations between different neighborhoods in the city of Pomona, California, and explores the historical, political and social factors that have shaped these spatial patterns. I argue that urban growth patterns in Pomona, which are historically marked by race and class segregation as a consequence of past discriminatory housing practices, have led to the disproportionate concentrations of air pollutants in low-income, Latino communities in South Pomona.

Due to the absence of a local air quality monitoring system, there is a lack of information about and understanding of how poor air quality may be …

Understanding Parent Beliefs And Attitudes Regarding Healthy Relationships And Sexuality Education: Bridging The Inclusivity Gap, Marie C. Zarrilli

Occupational Therapy Doctorate Capstone Projects

Children, adolescents, and young adults with Intellectual and Developmental Disabilities (IDD) are often excluded from receiving Comprehensive Sexuality Education (CSE), even though they are at increased vulnerability for sexual abuse and exploitation. Although some curricula are emerging that are adapted for individuals with IDD, rigorous effectiveness studies are sparse. The purpose of this capstone project was to empirically explore the beliefs, attitudes, and comfort level of parents with sexuality education program types and content regarding their own parent/child communication and the need for training and resources. This capstone project used a quantitative, cross-sectional, descriptive survey design. The survey consisted of …

Fostering Peer Evaluation Skills In Nursing Students, Lisa Dubose

Journal of the Arkansas Academy of Science

Nursing peer review is a professional practice in which nurses offer constructive, non-personal, practice-related feedback to fellow nurses. The use of nursing peer review has been recommended by the American Nurses Association (ANA 1988, 2014) and the American Nurses Credentialing Center (ANCC 2008). Despite being recommended by professional organizations, the use of peer review in nursing has not been widely implemented. Evaluation of nursing colleagues has the potential to enhance professional nursing, both in practice and in nursing education.

Fostering the skills needed to provide peers with evaluative feedback might best be accomplished if the process is started during nursing …

An Updated Checklist Of The Spiders (Arachnida: Araneae) Of Arkansas, Henry W. Robison, C. Renn Tumlison, Paula E. Cushing, Peggy R. Dorris

Journal of the Arkansas Academy of Science

A total of 510 species of spiders representing 43 families and 215 genera are herein reported from Arkansas. The most diverse families of state spiders were Salticidae (64 species), Lycosidae (59 species), Araneidae (55 species), and Gnaphosidae (54 species). Twelve families had only a single representative species in the state. Additional taxa will surely be added to the checklist with future taxonomic studies incorporating molecular analyses and additional collecting. This updated checklist is intended to be of use to arachnologists, researchers, naturalists, professional biologists, and managers in determining the biodiversity for Arkansas. We have worked to insure that the taxonomy …

Morphology Of Rathke’S Glands In The Alligator Snapping Turtle, Macrochelys Temminckii (Chelonia: Chelydridae), Stanley E. Trauth

Journal of the Arkansas Academy of Science

I examined the morphology of Rathke’s glands (RG) in the Alligator Snapping Turtle, Macrochelys temminckii, using light microscopy and scanning electron microscopy. This species possesses 4 pairs of RG (i.e., an axillary and three inframarginals) that are embedded beneath marginal bones and are named primarily according to the anatomical location of their orifices. These holocrine-type, exocrine, integumentary glands are anatomically and ultrastructurally similar to one another. Each gland contains a single and highly vascularized secretory lobule, which is bounded by a thick tunic of asymmetrically-arranged striated muscle bundles. Two types of secretory vacuoles were identified within the holocrine cells …