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2021

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Full-Text Articles in Medicine and Health Sciences

Teamstepps In A Pediatric Operating Room, Lisa Kerrick Jan 2021

Teamstepps In A Pediatric Operating Room, Lisa Kerrick

Regis University Student Publications (comprehensive collection)

Despite numerous patient safety and quality programs available and in use in the healthcare environment, adverse events in operating rooms continue to occur. The operating room is a complex and chaotic environment where teamwork is necessary for safe patient care. Team training is a strategy that improves teamwork. TeamSTEPPS is an evidence-based team training program designed to integrate teamwork into clinical practice. This project aims to determine if TeamSTEPPS communication tools and strategies improve the perception of teamwork and efficiency in a pediatric operating room. The outcome objectives for this project are to increase the perception of teamwork and improve …


Implementation Of A Pregnancy Intention Screening Question At A Federally Qualified Health Center, Diana Gue Jan 2021

Implementation Of A Pregnancy Intention Screening Question At A Federally Qualified Health Center, Diana Gue

Regis University Student Publications (comprehensive collection)

Objective: Process improvement project idea was examined due to the need to fulfill a requirement within a grant. One measure needed for the grant was a pregnancy intention screening question (PISQ) asked of women during their visits. There currently was no formal PISQ. The primary outcomes for this project are to measure effects of the addition of a PISQ on the provision of contraceptive counseling and/or contraceptive methods. Methods: The staff and providers were provided education of the workflow and documentation of the PISQ and the diagnosis codes for contraception counseling and methods. Data was collected three months prior to …


Np’S Perception Of Preparedness And Self-Efficacy Between Novice Nps That Participated In A Post Graduate Training Program And Those That Did Not, Tasha Bruner-Hill Jan 2021

Np’S Perception Of Preparedness And Self-Efficacy Between Novice Nps That Participated In A Post Graduate Training Program And Those That Did Not, Tasha Bruner-Hill

Regis University Student Publications (comprehensive collection)

The role transition from a registered nurse (RN) to a nurse practitioner (NP) can be challenging and stressful as the RN moves from often expert status back to novice status as an NP. The purpose of this qualitative, descriptive study was to explore if role transition was easier for novice NPs that participated in a post-graduate training program, then for those that did not. Following IRB approval for the study, a self-report tool consisting of 18 questions was emailed to a national sample of NPs who graduated 2014-2020 and practiced at least one year but not more than five years …


Uniting The Front: A Qualitative Exploration Of The Community Health Worker Covid-19 Pandemic Response In Connecticut, Serena Ly Jan 2021

Uniting The Front: A Qualitative Exploration Of The Community Health Worker Covid-19 Pandemic Response In Connecticut, Serena Ly

Public Health Theses

Background: Community health workers (CHWs) are becoming increasingly recognized for their contributions to community health. As the COVID-19 pandemic continues to devastate poor and underserved communities, leveraging CHWs’ experiences with vulnerable community members is key to developing an equity-centered pandemic response. This qualitative research study aimed to explore how CHWs have addressed emerging community needs and whether health and emergency management systems have fully integrated CHWs in the COVID-19 pandemic response. This study further aimed to assess, through CHWs perceptions, how well health systems have safeguarded CHWs’ health and wellbeing as they support impacted communities.

Methods: CHWs and their managers …


A Case Study Of Children's Programming In Transitional Housing, Crystal L. Coffman Jan 2021

A Case Study Of Children's Programming In Transitional Housing, Crystal L. Coffman

Occupational Therapy Doctorate Capstone Projects

Background: Female-headed households with children makeup nearly 30% of the homeless population, and are challenged to become self-sufficient while embodying multiple roles with inadequate supports (Bassuk, 2010; Crncec, 2008; Fisher, 2000; Schultz-Krohn & Tyminski, 2018). While there is growing literature to support the social-cultural and occupational needs of adults in this population, few programs and research efforts have explored the life skill and developmental needs of children (Fleary et al., 2019).

Purpose: The purpose and objectives of this capstone project were to examine the planning, execution, follow-up, and contextual adaptation of the programs provided to children and youth at a …


Downeast Maine Mat Expansion Project: Year 3 Final Data Summary, Mary Lindsey Smith Phd, Evelyn Ali Bs, Katharine Knight Mph, Tyler Egeland Ba Jan 2021

Downeast Maine Mat Expansion Project: Year 3 Final Data Summary, Mary Lindsey Smith Phd, Evelyn Ali Bs, Katharine Knight Mph, Tyler Egeland Ba

Substance Use Research & Evaluation

This report summarizes the collaborative effort of Healthy Acadia, its providers, the Downeast Substance Treatment Network, and Downeast Substance Use Response Coalition, to combat opioid use disorder (OUD) in Downeast Maine through multiple evidence-based strategies.

Project goals included the reduction of barriers to accessing medication-assisted treatment (MAT) and the enhancement of MAT services by improving provider capacity through training and implementation of best practice treatment.

For more information, please contact M. Lindsey Smith, PhD, [email protected]


Staff Perceptions Of The Health Call Center Workplace Environment, Eric Lee Escobedo-Wu Jan 2021

Staff Perceptions Of The Health Call Center Workplace Environment, Eric Lee Escobedo-Wu

Regis University Student Publications (comprehensive collection)

The complexities of the Health Call Center (HCC) amidst of a pandemic has caused an uptick in nurses and staff experiencing physical, emotional, and mental fatigue. An increase in sick calls during peak call days and times, breakroom discussion related to workload and competing patient and clinical priorities, and the consistent need to care for patients and caregivers, while maintaining familial and fiscal responsibilities and priorities contribute to the exhaustion of the nurses. The purpose of this Quality Improvement (QI) project was to use a structured survey tool and open-ended questions to identify HCC nurses’ perceptions of stressors and burnout …


Increasing Minority Representation In The Healthcare Field Through A Girl’S Summer Camp, Anna Christiansen, Dzifa Agbossey-Dimado, Adejoke Ayoola Jan 2021

Increasing Minority Representation In The Healthcare Field Through A Girl’S Summer Camp, Anna Christiansen, Dzifa Agbossey-Dimado, Adejoke Ayoola

Summer Research

  • Despite increasing diversity among the United States’ population, the healthcare workforce, particularly in highly skilled roles, has failed to keep pace. The underrepresentation of minority groups within healthcare professions comes at the expense of quality and access to care, patient satisfaction, acceptability, general experience, and health outcomes.
  • One promising approach to addressing this health inequity is increasing the diversity of the healthcare workforce across all skill-level roles so that it is representative of the population which it serves. Research suggests that exposing underrepresented groups to healthcare professions as a possible career path during formative career planning years (early middle school), …


Ua19/16/2 Softball Press Releases, Wku Athletic Media Relations Jan 2021

Ua19/16/2 Softball Press Releases, Wku Athletic Media Relations

WKU Administration Documents

Press releases, photos and game statistics for WKU softball team in 2021.


Ua19/16/2 Volleyball Press Releases, Wku Athletic Media Relations Jan 2021

Ua19/16/2 Volleyball Press Releases, Wku Athletic Media Relations

WKU Administration Documents

Press releases, photos and game statistics for WKU volleyball team in 2021.


Quantitative Eeg-Based Seizure Estimation In Super-Refractory Status Epilepticus, Saptharishi Lalgudi Ganesan, Ayham Alkhachroum, Johannes P. Koren, Julie Kromm, Nina Massad, Renz A. Reyes, Michael Miller, David Roh, Sachin Agarwal, Soojin Park, Jan Claassen Jan 2021

Quantitative Eeg-Based Seizure Estimation In Super-Refractory Status Epilepticus, Saptharishi Lalgudi Ganesan, Ayham Alkhachroum, Johannes P. Koren, Julie Kromm, Nina Massad, Renz A. Reyes, Michael Miller, David Roh, Sachin Agarwal, Soojin Park, Jan Claassen

Data and Test Instruments

No abstract provided.


Thrombotic Thrombocytopenic Purpura Temporally Associated With Bnt162b2 Vaccination In An Adolescent Successfully Treated With Caplacizumab, Saptharishi Lalgudi Ganesan Jan 2021

Thrombotic Thrombocytopenic Purpura Temporally Associated With Bnt162b2 Vaccination In An Adolescent Successfully Treated With Caplacizumab, Saptharishi Lalgudi Ganesan

Data and Test Instruments

No abstract provided.


The Effect Of Measurement Area Size On The Reliability Of Myocardial Iron Load Measurementin Cardiac Magnetic Resonance Imaging Examinations Of Thalassemia Patients, İbrahi̇m Önder Yeni̇çeri̇, Fati̇h Mehmet Azik, Funda Di̇nç Eli̇bol Jan 2021

The Effect Of Measurement Area Size On The Reliability Of Myocardial Iron Load Measurementin Cardiac Magnetic Resonance Imaging Examinations Of Thalassemia Patients, İbrahi̇m Önder Yeni̇çeri̇, Fati̇h Mehmet Azik, Funda Di̇nç Eli̇bol

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to evaluate the intraobserver and interobserver reliability of cardiac T2* MRI measurements in different region of interest (ROI) sizes. Materials and methods: Cardiac T2* MRIs of 24 thalassemia major patients were evaluated. Two different ROI sizes were used for measurement. In the first measurement, an ROI approximately 5 mm in diameter was used in the interventricular septal myocardium. In the other method, the whole ventricular septal myocardium was used as the measurement. The intraobserver and interobserver variabilities were assessed with the intraclass correlation coefficient (ICC). Results: The measurement of the first observer, the …


Work-Life Balance Policies And Productivity, Zilola Khashimova Jan 2021

Work-Life Balance Policies And Productivity, Zilola Khashimova

Physician Assistant Studies | Faculty Scholarship

To remain viable, businesses must stay competitive in the global marketplace of today, and to be competitive, businesses must maximize all their resources. Employees are a major resource of a business, and it is imperative that a business maximize the productivity of its employees to stay competitive. Employees who are stressed from demands and issues of family and life outside of work do not make productive employees. Work-life balance practices have been adopted by businesses to provide some relief for employees from this stress with the assumption is that these policies will decrease the stress of the employee making the …


Phased Return Of Students To 77 Transitional Kindergarten-8th Grade Schools With Cohesive Mitigation Strategies Serving As Protective Factors Against The Increase Of Covid-19 Cases In Marin County: September 2020-January 2021, Shayne Q. Paff, Rochelle Ereman, Lisa Santora, Bethany Dominik, Alana Mcgrath, Jasmine Soriano, Charis Baz, Matthew Willis, Michaela George Jan 2021

Phased Return Of Students To 77 Transitional Kindergarten-8th Grade Schools With Cohesive Mitigation Strategies Serving As Protective Factors Against The Increase Of Covid-19 Cases In Marin County: September 2020-January 2021, Shayne Q. Paff, Rochelle Ereman, Lisa Santora, Bethany Dominik, Alana Mcgrath, Jasmine Soriano, Charis Baz, Matthew Willis, Michaela George

Global Public Health | Faculty Scholarship

Background and objective

Earlier uncertain implications of the coronavirus disease 2019 (COVID-19) pandemic on the pediatric population prompted the authorities to close schools worldwide under the premise that school settings would serve as drivers of an increase in the cases of COVID-19. Safe and equitable full-in-person school instruction is a critical factor in the continued educational gains of children and for their general well-being. The objective of this study was to report epidemiological trends related to the increasing percentage of students returning to in-person instruction, the suspected in-school transmission of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the virus that …


Investing Into Domestic Manufacturing Of Critical Medication And Vaccines For The Federal Government, Sharon Low Jan 2021

Investing Into Domestic Manufacturing Of Critical Medication And Vaccines For The Federal Government, Sharon Low

All Reports

While the federal government has made numerous public announcements regarding their stimulus plan and promises to increase the domestic capacity to produce personal protective equipment, vaccines, and medical equipment, a critical aspect that has been neglected is the serious and ongoing shortages of critical medication. The government has promised to provide 4.28 billion to expand testing and contact tracing capacities, 7.5 billion towards PPE, and 500 million to the provinces and territories for “critical health care system needs and support for mitigation effects.” While these efforts as part of Trudeau’s Safe Restart Agreement are a good place to begin reducing …


Impact Of Covid-19 On The Italian And American Healthcare Systems : A Comparative Assessment, Bita Pejam, Jennifer Lam Jan 2021

Impact Of Covid-19 On The Italian And American Healthcare Systems : A Comparative Assessment, Bita Pejam, Jennifer Lam

All Reports

This report aims to examine and assess the impact of the COVID-19 global pandemic on the healthcare systems of the United States of America and Italy; two of the most heavily affected nations. Using data from December 2019 to January 2021, several consultations, and policy reviews, we identify risks and notable areas of issue in each nations’ approach to combating the virus. We focus our report particularly on the health policies and the governmental structures in place that contributed to each nations’ initial method of alleviating the impact of COVID-19. Our report compares the two healthcare systems and proposes a …


A Systematic Review Of Brainstem Contributions To Autism Spectrum Disorder, Ala Seif, Carly Shea, Susanne Schmid, Ryan A Stevenson Jan 2021

A Systematic Review Of Brainstem Contributions To Autism Spectrum Disorder, Ala Seif, Carly Shea, Susanne Schmid, Ryan A Stevenson

Anatomy and Cell Biology Publications

Autism spectrum disorder (ASD) is a neurodevelopmental disorder that affects one in 66 children in Canada. The contributions of changes in the cortex and cerebellum to autism have been studied for decades. However, our understanding of brainstem contributions has only started to emerge more recently. Disruptions of sensory processing, startle response, sensory filtering, sensorimotor gating, multisensory integration and sleep are all features of ASD and are processes in which the brainstem is involved. In addition, preliminary research into brainstem contribution emphasizes the importance of the developmental timeline rather than just the mature brainstem. Therefore, the purpose of this systematic review …


Gabab Receptor Agonist R-Baclofen Reverses Altered Auditory Reactivity And Filtering In The Cntnap2 Knock-Out Rat, Dorit Möhrle, Wenxuan Wang, Shawn N Whitehead, Susanne Schmid Jan 2021

Gabab Receptor Agonist R-Baclofen Reverses Altered Auditory Reactivity And Filtering In The Cntnap2 Knock-Out Rat, Dorit Möhrle, Wenxuan Wang, Shawn N Whitehead, Susanne Schmid

Anatomy and Cell Biology Publications

Altered sensory information processing, and auditory processing, in particular, is a common impairment in individuals with autism spectrum disorder (ASD). One prominent hypothesis for the etiology of ASD is an imbalance between neuronal excitation and inhibition. The selective GABAB receptor agonist R-Baclofen has been shown previously to improve social deficits and repetitive behaviors in several mouse models for neurodevelopmental disorders including ASD, and its formulation Arbaclofen has been shown to ameliorate social avoidance symptoms in some individuals with ASD. The present study investigated whether R-Baclofen can remediate ASD-related altered sensory processing reliant on excitation/inhibition imbalance in the auditory brainstem. …


Moyamoya Syndrome In An Infant With Aicardi-Goutières And Williams Syndromes: A Case Report, Jagraj S. Brar, Rahul Verma, Mohammed Al-Omari, Victoria M. Siu, Andrea V. Andrade, Michael T. Jurkiewicz, Saptharishi Lalgudi Ganesan Jan 2021

Moyamoya Syndrome In An Infant With Aicardi-Goutières And Williams Syndromes: A Case Report, Jagraj S. Brar, Rahul Verma, Mohammed Al-Omari, Victoria M. Siu, Andrea V. Andrade, Michael T. Jurkiewicz, Saptharishi Lalgudi Ganesan

Paediatrics Publications

Stroke in infancy is a rare phenomenon but can lead to significant long-term disability. We present the story of a 6-month-old Old Order Amish infant with underlying Williams syndrome, a rare neurodevelopmental disorder caused by a microdeletion, encompassing the elastin gene that produces abnormalities in elastic fibers of the lungs and vessels. This infant presented with lethargy, irritability, and a new-onset generalized tonic-clonic seizure. Brain magnetic resonance imaging (MRI) was consistent with ischemic stroke in the supratentorial regions. MR angiogram demonstrated bilateral narrowing of the internal carotid arteries with ivy sign, suggestive of Moyamoya. Moyamoya disease/syndrome is a cerebrovascular condition …


Pannexin 1 Binds Β-Catenin To Modulate Melanoma Cell Growth And Metabolism, Samar Sayedyahossein, Kenneth Huang, Zhigang Li, Christopher Zhang, Alexandra M. Kozlov, Danielle Johnston, Daniel Nouri-Nejad, Lina Dagnino, Dean H. Betts, David B. Sacks, Silvia Penuela Jan 2021

Pannexin 1 Binds Β-Catenin To Modulate Melanoma Cell Growth And Metabolism, Samar Sayedyahossein, Kenneth Huang, Zhigang Li, Christopher Zhang, Alexandra M. Kozlov, Danielle Johnston, Daniel Nouri-Nejad, Lina Dagnino, Dean H. Betts, David B. Sacks, Silvia Penuela

Paediatrics Publications

Melanoma is the most aggressive skin malignancy with increasing incidence worldwide. Pannexin1 (PANX1), a member of the pannexin family of channel-forming glycoproteins, regulates cellular processes in melanoma cells including proliferation, migration, and invasion/metastasis. However, the mechanisms responsible for coordinating and regulating PANX1 function remain unclear. Here, we demonstrated a direct interaction between the C-terminal region of PANX1 and the N-terminal portion of β-catenin, a key transcription factor in the Wnt pathway. At the protein level, β-catenin was significantly decreased when PANX1 was either knocked down or inhibited by two PANX1 blockers, Probenecid and Spironolactone. Immunofluorescence imaging showed a disrupted pattern …


Investigation Of Digital Technology Use In The Transition To Parenting: Qualitative Study, Lorie Donelle, Jodi Hall, Bradley Hiebert, Kimberley Jackson, Ewelina Stoyanovich, Jessica Lachance, Danica Facca Jan 2021

Investigation Of Digital Technology Use In The Transition To Parenting: Qualitative Study, Lorie Donelle, Jodi Hall, Bradley Hiebert, Kimberley Jackson, Ewelina Stoyanovich, Jessica Lachance, Danica Facca

Nursing Publications

Background: The transition to parenting—that is, the journey from preconception through pregnancy and postpartum periods—is one of the most emotionally charged and information-intense times for individuals and families. While there is a developing body of literature on the use and impact of digital technology on the information behaviors of children, adolescents, and young adults, personal use of digital technology during the transition to parenting and in support of infants to 2 years of age is relatively understudied. Objective: The purpose of this study was to enhance our understanding of the ways digital technologies contribute to the experience of the transition …


Effects Of Maternal Obesity And Gestational Diabetes Mellitus On The Placenta: Current Knowledge And Targets For Therapeutic Interventions, Samantha Bedell, Janine Hutson, Barbra De Vrijer, Genevieve Eastabrook Jan 2021

Effects Of Maternal Obesity And Gestational Diabetes Mellitus On The Placenta: Current Knowledge And Targets For Therapeutic Interventions, Samantha Bedell, Janine Hutson, Barbra De Vrijer, Genevieve Eastabrook

Obstetrics & Gynaecology Publications

Obesity and gestational diabetes mellitus (GDM) are becoming more common among pregnant women worldwide and are individually associated with a number of placenta-mediated obstetric complications, including preeclampsia, macrosomia, intrauterine growth restriction and stillbirth. The placenta serves several functions throughout pregnancy and is the main exchange site for the transfer of nutrients and gas from mother to fetus. In pregnancies complicated by maternal obesity or GDM, the placenta is exposed to environmental changes, such as increased inflammation and oxidative stress, dyslipidemia, and altered hormone levels. These changes can affect placental development and function and lead to abnormal fetal growth and development …


Biofeedback As An Intervention For Persistent Post-Concussive Symptoms: A Randomized Feasibility Trial, Marquise M. Bonn, Liliana Alvarez, Laura J. Graham, James W. Thompson, James P. Dickey Jan 2021

Biofeedback As An Intervention For Persistent Post-Concussive Symptoms: A Randomized Feasibility Trial, Marquise M. Bonn, Liliana Alvarez, Laura J. Graham, James W. Thompson, James P. Dickey

Physical Therapy Publications

Background

Case reports indicate that low-resolution electromagnetic tomography neurofeedback and heart rate variability biofeedback may improve physiological functioning in individuals with persistent post-concussive symptoms. However, it is unclear whether larger-scale studies are feasible.

Purpose

To evaluate the feasibility of a combined low-resolution electromagnetic tomography neurofeedback and heart rate variability biofeedback intervention for individuals with persistent post-concussive symptoms.

Methods

Individuals with persistent post-concussive symptoms were randomized into intervention and control groups, and their baseline and post-test assessments were compared to a healthy control group. Outcomes included self-report questionnaires, resting electroencephalograph and electrocardiograph recordings, and a driving simulation task. Participants in the …


Examining How Children's Gender Influences Parents’ Perceptions Of The Local Environment And Their Influence On Children's Independent Mobility, Alina Medeiros, Andrew F. Clark, Gina Martin, Jamie A. Seabrook, Jason Gilliland Jan 2021

Examining How Children's Gender Influences Parents’ Perceptions Of The Local Environment And Their Influence On Children's Independent Mobility, Alina Medeiros, Andrew F. Clark, Gina Martin, Jamie A. Seabrook, Jason Gilliland

Paediatrics Publications

Physical inactivity among children is a public health concern. Children's ability to travel independently is associated with increased physical activity and social connectedness. Consequently, it is concerning that children's independent mobility has decreased in recent years. Studies have highlighted that rates of independent mobility vary by gender; this study analyzed how correlates of independent mobility vary between boys (n = 476) and girls (n = 618) attending 32 elementary schools in Southwestern Ontario. Hierarchical logistic regression modeling methods were used. All analyzes were stratified by gender. For boys, age was negatively associated with travel with peers. Having one or more …


Correlates Of Lifetime And Past Month Vape Use In A Sample Of Canadian University Students, Jamie A. Seabrook, Jasna Twynstra, Jason A. Gilliland Jan 2021

Correlates Of Lifetime And Past Month Vape Use In A Sample Of Canadian University Students, Jamie A. Seabrook, Jasna Twynstra, Jason A. Gilliland

Paediatrics Publications

Introduction: This study examines correlates of lifetime (ie, ever vaped) and past month vape use among students aged 17 to 19 years, 20 to 25 years, and 26+ years from Western University in London, Ontario. The secondary objective is to assess lifetime and past month vape use among students not of legal age to purchase vaping products in Ontario (ie, those 17 to 18 years only). Methods: Using Qualtrics, a cross-sectional survey was sent via email to all students at Western University (N = 38 442), assessing their current and past risk-taking behaviors, mental health, sociodemographic characteristics, as well as …


The Quantity And Composition Of Household Food Waste During The Covid-19 Pandemic: A Direct Measurement Study In Canada, Haley Everitt, Paul Van Der Werf, Jamie A. Seabrook, Alexander Wray, Jason A. Gilliland Jan 2021

The Quantity And Composition Of Household Food Waste During The Covid-19 Pandemic: A Direct Measurement Study In Canada, Haley Everitt, Paul Van Der Werf, Jamie A. Seabrook, Alexander Wray, Jason A. Gilliland

Paediatrics Publications

The COVID-19 pandemic may have amplified the environmental, social, and economic implications of household food waste. A better understanding of household food wasting during the pandemic is needed to improve the management of waste and develop best practices for municipal waste management programs under crisis circumstances. A waste composition study was undertaken with 100 single-family households across the city of London, Ontario, Canada to determine the quantity and composition of household food waste disposed in June 2020, during the first wave of the COVID-19 pandemic. This study examines how household demographic, socioeconomic, and neighbourhood food environment characteristics influence household food …


Examining How Changes In Provincial Policy On Vape Marketing Impacted The Distribution Of Vaping Advertisements Near Secondary Schools In London, Ontario, Gina Martin, Drew D. Bowman, Megan Graat, Andrew F. Clark, Alexander J. Wray, Zoe Askwith, Jamie A. Seabrook, Jason A. Gilliland Jan 2021

Examining How Changes In Provincial Policy On Vape Marketing Impacted The Distribution Of Vaping Advertisements Near Secondary Schools In London, Ontario, Gina Martin, Drew D. Bowman, Megan Graat, Andrew F. Clark, Alexander J. Wray, Zoe Askwith, Jamie A. Seabrook, Jason A. Gilliland

Paediatrics Publications

Objectives: On January 1, 2020, the Government of Ontario passed a regulation banning vaping advertisements by retailers, apart from specialty shops. A motivation for this ban was to limit youth exposure to vaping advertisements. The primary goal of this research was to evaluate the impact of this ban on the number and density of vaping advertisements surrounding secondary schools. Additionally, we examined whether the number of vaping advertisements varied by school socio-demographic characteristics. Methods: This study used a pre-post design. Audits were conducted December 2019 (pre-ban) and again January to February 2020 (post-ban), to identify vaping advertisements within 800 m …


Sensitivity Of Arterial Spin Labeling For Characterization Of Longitudinal Perfusion Changes In Frontotemporal Dementia And Related Disorders, Tracy Ssali, Udunna C. Anazodo, Lucas Narciso, Linshan Liu, Sarah Jesso, Lauryn Richardson, Matthias Günther, Simon Konstandin, Klaus Eickel, Frank Prato, Elizabeth Finger, Keith St. Lawrence Jan 2021

Sensitivity Of Arterial Spin Labeling For Characterization Of Longitudinal Perfusion Changes In Frontotemporal Dementia And Related Disorders, Tracy Ssali, Udunna C. Anazodo, Lucas Narciso, Linshan Liu, Sarah Jesso, Lauryn Richardson, Matthias Günther, Simon Konstandin, Klaus Eickel, Frank Prato, Elizabeth Finger, Keith St. Lawrence

Paediatrics Publications

Background: Advances in the understanding of the pathophysiology of frontotemporal dementia (FTD) and related disorders, along with the development of novel candidate disease modifying treatments, have stimulated the need for tools to assess the efficacy of new therapies. While perfusion imaging by arterial spin labeling (ASL) is an attractive approach for longitudinal imaging biomarkers of neurodegeneration, sources of variability between sessions including arterial transit times (ATT) and fluctuations in resting perfusion can reduce its sensitivity. Establishing the magnitude of perfusion changes that can be reliably detected is necessary to delineate longitudinal perfusion changes related to disease processes from the effects …


The Risk Of Physical Multimorbidity In People With Psychotic Disorders: A Systematic Review And Meta-Analysis, Myanca Rodrigues, Joshua C. Wiener, Saverio Stranges, Bridget L. Ryan, Kelly K. Anderson Jan 2021

The Risk Of Physical Multimorbidity In People With Psychotic Disorders: A Systematic Review And Meta-Analysis, Myanca Rodrigues, Joshua C. Wiener, Saverio Stranges, Bridget L. Ryan, Kelly K. Anderson

Epidemiology and Biostatistics Publications

Background: The occurrence of multiple co-occurring chronic health conditions, known as multimorbidity, is associated with decreases in quality of life for patients and poses unique challenges for healthcare systems. Since people with psychotic disorders have an excess of physical health conditions compared to the general population, they may also be at a higher risk for multimorbidity. We conducted a systematic review and meta-analysis to quantify the prevalence and excess risk of multimorbidity among people with psychotic disorders, relative to those without psychosis.

Methods: We searched the MEDLINE, EMBASE, and PsycINFO databases, and conducted forward and backward citation tracing of included …