Medicine and Health Sciences Commons^™

Understanding College Student Emotional Functioning During Covid-19, Dominique Marie Giroux

Theses and Dissertations

The novel coronavirus has resulted in mass infection and death. To prevent spread of the virus, colleges and universities shut down and transitioned to remote learning, which mandated all college students to leave residential housing and relocate to a permanent address. Previous literature suggests college students who experienced housing displacement due to a natural disaster reported heightened distress and poorer overall functioning (Davis, Grills-Taquechel, & Ollendick, 2010). Prior to the COVID-19 outbreak, college student mental health was deemed a public health concern, however, it is expected to worsen following the outbreak (Galea, Merchant, & Lurie, 2020). Researchers suggest peer support …

A Timecourse Based Dermatotoxicity Evaluation Of Mechlorethamine On Damage And Repair Related Protein Expression In The Mouse Ear Vesicant Model, Ganming Mao

Theses and Dissertations

Mechlorethamine (HN2) is a type of nitrogen mustard alkylating agent that has been widely applied as an anticancer drug. HN2 is an analog of the corrosive reagent sulfur mustard, which is highly reactive with skin and organisms exposed to HN2 develop significant skin irritation, edema, erythema, and disruption of the dermal-epidermal junction (DEJ). These pathological affects lead to tissue damage, activate wound repair mechanisms and, if unresolved, result in necrosis. The purpose of the present study was to evaluate the time-dependent effects of HN2 on the expression of three different proteins using immunohistochemistry (IHC) and previously prepared and preserved formalin-fixed …

A Latinx Critical Race Theoretical Approach To Testimonios Of Latinx School Psychologists, Karen Yulieann Ramírez

Selected Full Text Dissertations, 2011-

As a Latina school psychologist, I use Latinx Critical Race framework with testimonios as methodology to document the individual and collective experiences and perspectives of six Latinx school psychologists in urban and suburban school settings regarding the role that race plays in the special education process. Their testimonios reveal how they are racialized in their profession through their intersecting identities of race, ethnicity, culture, and language. In particular, they testify to their everyday experiences of racial microaggressions, in which they are viewed through a deficit lens by supervisors, colleagues, and the parents of the students they serve. In addition, their …

In Vitro And In Silico Approaches To Evaluate The Pharmacokinetics And Pharmacodynamics Of Combination Antibiotic Therapy Against Drug-Resistant Bacteria, Sharmistha Das

Selected Full-Text Dissertations 2020-

This thesis focuses on combating antibacterial resistance by developing novel in vitro and in silico techniques. In vitro techniques such as in vitro pharmacodynamic (IVPD) modeling are powerful tools for investigating pharmacokinetic and pharmacodynamic response of antibiotics against bacteria. The standard IVPD model in the literature works for simulating monotherapy and combination therapy of drugs having similar half live. But it does not work for combination therapy of drugs having different half live. The method present in the literature for combination therapy of drugs with different half live was described by Blaser. By utilizing Blaser’s method, it was observed that …

Multivariate Pharmametric Approach As A Solution To The Challenges Associated With In-Situ Uv Fiber-Optic Dissolution Testing, Rushaben Maulik Sardhara

Selected Full-Text Dissertations 2020-

The advancement and automation in analytical techniques is a current thrust of the pharmaceutical industry. It has been over 30 years since unconventional semi or fully automatic methods have begun to be developed to achieve the measurement in-situ in the dissolution test apparatus. The current study focuses on the fiber optic dissolution system (FODS), its challenges, and solutions to the challenges. The inaccuracy in dissolution profile predictions due to some limitations associated with the FODS makes it difficult to adopt this advanced automated technology for various purposes. The traditional dissolution methods are still widely used even though they are time-consuming …

Ex Vivo Dermis Microdialysis: A Tool For Bioequivalence Testing Of Topical Dermatological Drug Product (Demonstration Of Proof Of Concept And Testing), Mohammad Asif Ali

Selected Full-Text Dissertations 2020-

Clinical response to most topical dermatological drug products (TDDP) depends on the availability of the drug in the dermis. Dermal Microdialysis (dMD) is a sampling technique that permits measuring the concentration of a drug over time, in vivo, directly into the target tissue, the dermis. The pharmacokinetic parameters obtained from such studies may help to optimize the development of TDDP and potentially can be applied to the assessment of TDDP bioequivalence. However, these studies require several hours or even days of continuous sampling that makes it often stressful and unpractical for human subjects as well as animals. The goal of …

Understanding Of The Drug-Drug Co-Crystallized Solid Structure – Mechanical Properties And Improved Tableting Performance Of High Dose Metformin Hci To Optimize The Tablet Size, Jayshil Akhilkumar Bhatt

Selected Full-Text Dissertations 2020-

Crystal engineering has been widely explored to design and develop crystalline forms of drugs to address issues related to solubility, permeability, stability, bioavailability, and other properties without impacting the therapeutic efficacy of the drug. In this exploration, we aim to address the existing limitation of metformin HCl (MET) using the cocrystallization technique, an effective tool of crystal engineering. MET, an FDA-approved anti-hyperglycemic drug, is one of the most widely prescribed treatments for type II diabetes mellitus. MET is known to suffer from several limitations due to physicochemical properties and poor mechanical and structural properties, which influence the tableting performance of …

Investigation Of Dermal Bioavailability And Bioequivalence Of Topical Dermatological Drug Products Via Microdialysis In Rabbits, Sharareh Iran Senemar

Selected Full-Text Dissertations 2020-

There is no standard technique to measure skin pharmacokinetics (PK) and therefore to evaluate bioequivalence (BE) for topical dermatological drug products (TDDPs). Generic companies are required to conduct costly clinical endpoint studies to evaluate BE. For this reason, regulatory agencies are looking for more efficient methods to measure the drug bioavailability of TDDPs. It is about 40 years since microdialysis was developed as a tool to study tissue biochemistry in animals, specifically, neurotransmitter release in the rodent brain, and 30 years since it was applied to study skin PK. However, improvements in the dermal microdialysis (dMD) technique are required to …

Effectiveness Of An Injury Prevention Program On Division I Track & Field Runners, Courtney Almendinger Spt, Aaron Lemon Spt, Brooke Ireland Spt, Anna Sudbeck Spt

Physical Therapy Student Research Projects

No abstract provided.

Competitive Aging Cyclists: Variables Associated With Successful Performance, Alana Hall Spt, Cayla Hirsch Spt, Kelsey Knecht Spt, Miranda Ristau Spt

Physical Therapy Student Research Projects

No abstract provided.

The Effects Of Cycling On Bone Health In Senior Athletes, Micah Hettinger Spt, Chesney Nagel Spt, Ember Newman Spt, Ashley Wilson Spt

Physical Therapy Student Research Projects

No abstract provided.

The Influence Of Hop Width During The Crossover Hop Test, Jon Albright Spt, Barry Ehlers Spt, Taylor Glasoe Spt, Shanna Selby Spt

Physical Therapy Student Research Projects

No abstract provided.

The Effects Of Congenital Muscular Torticollis On Postural Control Among Four To Six - Year - Old Children, Josh Henderson, Spt, Alyssa Matson Spt, Nicci Mcguire Spt, Brett Steffen Spt

Physical Therapy Student Research Projects

No abstract provided.

A Cross - Sectional Observational Study Testing Reliability And Validity For Tactile Acuity With Grid Localization In Healthy Patients, Molly Horning Spt, Luke Laycock Spt, Leslie Terwilliger Spt

Physical Therapy Student Research Projects

No abstract provided.

Knowledge Of Pelvic Health Among Undergraduate Students, Taylor Hovaldt Spt, Kelsey Grosshuesch Spt, Erica Thyen Spt, Lexie Weier Spt

Physical Therapy Student Research Projects

No abstract provided.

Resilience And Burnout: Students Vs Practicing Clinicians, Chloe Cornemann Spt, Sydney Giese Spt, Abby Mettler Mettler Spt, Hannah Wolzen Spt

Physical Therapy Student Research Projects

No abstract provided.

Implementation And Standardization Of Evidence Based Practice For Reprocessing Of Flexible Endoscopes, Patricia Dumonceaux, Jenna Rooda, Dena Walz

Nursing Posters

To improve patient safety and quality of care by implementing a standardized process for high level disinfection (HLD) of flexible endoscopes

Increasing Access To Data Through Microsoft's Power Bi, Rumana Ahmad, Kristi Patterson

Nursing Posters

What is Power BI?

• A collection of software services, apps, and connectors that work together to turn unrelated sources of data into coherent, visually immersive, and interactive insights.

What’s in it for me?

• Users can quickly & easily explore trends for CC inpatients across common outcome measures including case counts, length of stay, mortality, & unplanned readmissions to help identify variation & opportunity for improvement. For example, compare COPD patient case counts, length of stay,and in-house mortality across CC hospitals.

No One Goes Missing: Creating An Elopement Risk Safe Plan Of Care, Jennifer Burris, Kathryn Collins, Holly Kockler, Tiffany Omann-Bidinger, Elizabeth Plante

Nursing Posters

To identify patients at risk for elopement by developing an evidence-based elopement risk screening tool and plan of care.

Admission Documentation Overhaul, Jennifer Burris, Holly Kockler, Hillary Waldum

Nursing Posters

Improve the admission documentation workflow by revamping the admission Navigator and Functional Health Assessment

High Reliability Principles In Safety, Abby Henderson, Leigh Klaverkamp

Nursing Posters

• Subject matter experts compare actual performance to expected performance.
• A standard set of questions for specific subtypes of events help establish trends.
• HRO's (High Reliability Organization) equip leaders and frontline staff to spot systemic causes of human error.

Improving Hepatitis B Vaccination Rates In Nephrology Patients With Chronic Kidney Disease: A Qi Initiative, Jill Swanson

Nursing Posters

• Hepatitis B vaccination is an important health maintenance preventative measure for patients with chronic kidney disease (CKD)
• Prior to initiating dialysis, hepatitis B vaccination administration is proven to be more effective than waiting until patients begin dialysis treatments.
• Efficacy and immune response of the hepatitis B vaccine is greater when kidney function is greater
• To better improve hepatitis B vaccine administration among the CKD stage 4 population, education measures and Epic modifiers will be implemented to achieve change
• Nursing knowledge and hepatitis B vaccine administration will improve after implementation of these measures

A New Approach To Sternal Precautions: Keep Your Move In The Tube, Kelijo Fernholz, Jayna Theis, Erik Anderson

Nursing Posters

Purpose:

• To guide patients and staff in a new approach to sternal precautions following median sternotomy

Current Practice:

• 10-pound lifting restriction for 4 weeks
• 20-pound lifting restriction until 3 months post operation
• Limited arm exercises
• Sit to stand push restrictions

Why Change:

• Literature review demonstrates great variation in sternal precautions
• Currently too restrictive; may hinder recovery and long-term mobility. Too many restrictions can create fear of movement, resulting in short term rehab discharge needs
• To create more independence for the patient, less reliant on family members for ADLs and basic needs. Patients to return to regular home and work activities …

Performance Improvement Leadership Rounding Implementation, Dena Walz

Nursing Posters

To improve patient experience scores and address patient concerns in real time.

A proactive behavior that facilitates leaders building relationships with patients and families, managing expectations, and achieving and validating consistency of key behaviors.

A member of leadership will conduct a purposeful conversation with a chosen patient three days a week regarding the care provided during their procedural appointment.

Contemporary Treatment Options For Pulmonary Embolism, Tanya Glenz, Teresa Jahn

Nursing Posters

Purpose:

Provide RNs education on the classifications of PEs and new catheter directed treatment options.

Significance:

• PE remains a common and lethal entity
• PE is the 3rd leading cause of cardiovascular death in hospitalized patients (60,000-1000,000 per year)
• 150,000-250,000 PE related hospitalizations per year
• RNs must be knowledgeable of the classifications of PEs and catheter directed therapies to promote positive patient outcomes
• Prior to catheter directed therapies, submassive PEs had a mortality rate up to 20% at 3 months and were traditionally treated with IV heparin, or oral anticoagulant therapy

Routine Post Surgical Vital Signs: Time For A Change, Kristina Kjellberg, Elizabeth Plante, Sadie Seezs

Nursing Posters

Purpose Statement:

The purpose of this evidence-based practice project is to evaluate the current routine post operative vital signs and determine if reduced frequency of vital signs is as effective in identifying deterioration after a post anesthesia care unit (PACU) discharge.

Synthesis of Evidence:

• Patient survival in the post operative time period is maximized with the recognition and management of abnormal vital signs
• Post op periods can carry great respiratory and circulatory complications, which are identified by abnormal vital signs especially heart rate and blood pressure
• Multiple sources have identified that current frequency of post operative vital signs is based …

Rapid Evaluation Teams (Ret): No Longer Just For Hospitals, Amanda Thorson

Nursing Posters

Study:

Everyone goes to the Nursing Home for End of Life - Right? Wrong Cumulatively, over a 4-year study there were 678 residents with Full Code status residing at Carris Health Care Center and 687 residents the DNR/DNI status. That is only a 10-resident different between Full Code and DNR/DNI

Plan:

• Improve long-term care staff's ability to call for, and receive, support to rapidly evaluate and address an urgent or concerning situation.
• Need for this plan is supported by increased number of OHFC substantiated events related to code status in MN and number of residents with Full Code status in …

Suspension Of Independent Double-Check For Subq Insulin Administration, Mallory Mondloch, Jennifer Watson

Nursing Posters

Study:

After a 1-month pilot of suspending the dual sign-off/independent double-check process, 160/163 random subQ insulin administrations from various units were administered correctly. This yielded a 98% success rate. No patient harm occured.

Plan:

Per Institute of Safe Medication Practices, dual sign-offs/independent double-checks are more effective for select high risk meds and not all. Since implementation of the insulin calculator, medication errors related to subQ insulin administration have reduced compared to previously when solely two licensed staff members performed a manual, independent double-check. After implementation of the validated eMAR tool - the insulin calculator - it was still required for …

A Practice Innovation To Improve Staff Vaccination Knowledge And Skills, Ijeoma Ugochukwu

Nursing Posters

Abstract:

The practice improvement project explored the best practices for equipping CentraCare Health System's (CCHS) Licensed Practical Nurses (LPNs) and Certified Medical Assistants' (CMAs) with childhood vaccination knowledge and communication skills necessary to educate hesitant patients and parents about the benefits of vaccination compliance. Innovative computer-based education (CBE) was identified and developed to empower LPNs and CMAs working in the ambulatory setting with childhood vaccination knowledge and communication skills to improve their ability to educate hesitant patients and parents about the benefits of vaccination. The CBE module was guided by the Theory of Planned Behavior in identifying vaccination knowledge and …

Homelessness And Diabetes: A Review To Provide Education To Homeless Individuals And Organizations, David W. Grewe, Mckenzie J. Kostreva, Karly Kroeten

All Electronic Theses and Dissertations

Diabetes is a disease that is prevalent in both the United States, and within the homeless population. This project outlines what T2DM is, its prevalence in the homeless population, and then barriers to treatment that the homeless face. Educational material and information regarding diabetes is severely lacking in the homeless population. There are many organizations that exist to aid homeless individuals in the Minneapolis/Saint Paul area. This project is specifically working with an organization called Helping Homeless Minnesota. By researching information on T2DM, homelessness, and educational materials available, resources have been created for Helping Homeless MN. The resources are meant …