Medicine and Health Sciences Commons^™

Will The Virus Continue To Impact The World?, Anonymous

Community Reflections

A reflection assignment for Western Civilization: Since 1500 HI-102-N. It was written on 2/24/21 and it talks about my experiences during the pandemic. It is hard to imagine what the young kids are going to grow up with, if this virus continues to impact the world.

Everything Resembled A Ghost Town, Anonymous

Community Reflections

Personal reflection paper. I remember going for a drive and just seeing everything dark with no one around and I couldn’t help but think about how depressing it was to see everything resemble a ghost town.

Disparities In The Country Unfold Before Me, Ella Anonymous

Community Reflections

My Covid-19 personal reflection. In some parts of the country, mask mandates were created and followed, yet elsewhere people were packed on beaches without a mask in sight.

Mahwah Class Of 2020, Jacqueline Paruszek

Community Reflections

Class assignment. This lifestyle in the COVID pandemic has become the new normal and it is hard to think about life without masks, social distancing, sweatpants every day, and sanitizing whenever I get the chance.

A Comprehensive Overview Of Recent And Past Pandemics, Anonymous

Community Reflections

Class assignment for Professor Marino, Western Civilization HI-102. I felt it was my duty to continue volunteering my time and service as an Emergency Medical Technician (EMT).

March 13, 2020: Excitement And Anxiety, Caitlin Anonymous

Community Reflections

My primary source paper covers my feelings about covid from when it first started, to the midst of the pandemic and my hopes for the future. I also discuss what I learned or gained from experiencing a pandemic.

What It May Be Like After The Chaos, Kassidy Pratt

Community Reflections

The paper I wrote reflects on my first hand experiences and thoughts during my senior year with COVID-19. I started with the beginning the pandemic and how hard it was to accept what was happening. Then I move to talk about how I accepted it and learned to live with it in the new "normal."

Days Started To Blend Together, Anonymous

Community Reflections

5 year embargo applies to this Covid reflection paper. High school felt unfinished. When the time came to make a decision about where I was going to go to school in the fall, I was very conflicted.

Time With Family Is Valuable, Anonymous

Community Reflections

What did help me get through this pandemic was running and watching movies. Almost a year into this pandemic, things about my way of life are still the same, but it taught me who my true friends are and that time with family is valuable.

Missed Out On, To Me, The Best Part Of High School, Anonymous

Community Reflections

My Covid-19 reflection. Spending time with friends and family, traveling, and just being able to experience life have all been put on pause for who knows how long.

The World Had Come To A Pause, Brianna Anonymous

Community Reflections

This personal reflection gives information on covid-19 and how hard it was for not only myself but medical staff.

Quality Time With My Family Really Warmed My Heart, Anonymous

Community Reflections

Quarantine was definitely scary and sad not being able to do our everyday activities but being able to spend quality time with my family really warmed my heart.

The Pandemic Has Been The Hardest Time Of My Life, Jessica Zarrilli

Community Reflections

Class assignment. 2020 started off as a regular year, we counted down from ten and the clock struck twelve. No one knew what the future would hold.

Barriers And Facilitators To The Implementation Of Large‑Scale Nutrition Interventions In Africa: A Scoping Review, Obidimma Ezezika, Jenny Gong, Hajara Abdirahman, Daniel Sellen

Health Studies Publications

The efective implementation of large-scale nutrition interventions in Africa is an ongoing challenge. This scoping review identifes and explores the barriers and facilitators to the implementation of large-scale nutrition interventions in the African region. We searched PubMed, EMBASE, Scopus, ERIC, and Web of Science using search terms focused specifcally on barriers and facilitators to the implementation of nutrition interventions in Africa. To supplement the database search, reference lists in publications included for full-text review were also examined to identify eligible articles for inclusion. Eligible studies underwent quality assessment, and a directed content analysis approach to data extraction was conducted and …

2021-02-26_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled. It is updated Monday - Saturday.
This report is provisional and subject to change. City of Detroit and Wayne County are reported separately. MDHHS began tracking probable cases April 5, 2020. FCI indicates federal correctional institute. MDOC indicates Michigan Department of Corrections. Diagnostic tests, including nucleic acid amplification/real-time polymerase chain reaction (NAAT/RT-PCR) and rapid virus antigen detection point of …

2021-02-26_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

Preclinical Evaluation Of Artesunate As An Antineoplastic Agent In Ovarian Cancer Treatment, Anthony Mcdowell Jr., Kristen S. Hill, Joseph Robert Mccorkle, Justin W. Gorski, Yilin Zhang, Ameen A. Salahudeen, Frederick R. Ueland, Jill M. Kolesar

Obstetrics and Gynecology Faculty Publications

BACKGROUND: Ovarian cancer is the deadliest gynecologic malignancy despite current first-line treatment with a platinum and taxane doublet. Artesunate has broad antineoplastic properties but has not been investigated in combination with carboplatin and paclitaxel for ovarian cancer treatment.

METHODS: Standard cell culture technique with commercially available ovarian cancer cell lines were utilized in cell viability, DNA damage, and cell cycle progression assays to qualify and quantify artesunate treatment effects. Additionally, the sequence of administering artesunate in combination with paclitaxel and carboplatin was determined. The activity of artesunate was also assessed in 3D organoid models of primary ovarian cancer and RNAseq …

Limitations Of Transformers On Clinical Text Classification, Shang Gao, Mohammed Alawad, Michael Todd Young, John Gounley, Noah Schaefferkoetter, Hong-Jun Yoon, Xiao-Cheng Wu, Eric B. Durbin, Jennifer Doherty, Antoinette Stroup, Linda Coyle, Georgia D. Tourassi

Kentucky Cancer Registry Faculty Publications

Bidirectional Encoder Representations from Transformers (BERT) and BERT-based approaches are the current state-of-the-art in many natural language processing (NLP) tasks; however, their application to document classification on long clinical texts is limited. In this work, we introduce four methods to scale BERT, which by default can only handle input sequences up to approximately 400 words long, to perform document classification on clinical texts several thousand words long. We compare these methods against two much simpler architectures -- a word-level convolutional neural network and a hierarchical self-attention network -- and show that BERT often cannot beat these simpler baselines when classifying …

Differential Leukocyte And Platelet Profiles In Distinct Models Of Traumatic Brain Injury, William Brad Hubbard, Meenakshi Banerjee, Hemendra J. Vekaria, Kanakanagavalli Shravani Prakhya, Smita Joshi, Qingjun Wang, Kathryn E. Saatman, Sidney W. Whiteheart, Patrick G. Sullivan

Spinal Cord and Brain Injury Research Center Faculty Publications

Traumatic brain injury (TBI) affects over 3 million individuals every year in the U.S. There is growing appreciation that TBI can produce systemic modifications, which are in part propagated through blood–brain barrier (BBB) dysfunction and blood–brain cell interactions. As such, platelets and leukocytes contribute to mechanisms of thromboinflammation after TBI. While these mechanisms have been investigated in experimental models of contusion brain injury, less is known regarding acute alterations following mild closed head injury. To investigate the role of platelet dynamics and bioenergetics after TBI, we employed two distinct, well-established models of TBI in mice: the controlled cortical impact (CCI) …

Rural Residents' Perspectives On An Mhealth Or Personalized Health Coaching Intervention: Qualitative Study With Focus Groups And Key Informant Interviews, Nancy Schoenberg, Madeline Dunfee, Hannah Yeager, Matthew Rutledge, Angela Pfammatter, Bonnie Spring

Behavioral Science Faculty Publications

BACKGROUND: Compared with national averages, rural Appalachians experience extremely elevated rates of premature morbidity and mortality. New opportunities, including approaches incorporating personal technology, may help improve lifestyles and overcome health inequities.

OBJECTIVE: This study aims to gather perspectives on whether a healthy lifestyle intervention, specifically an app originally designed for urban users, may be feasible and acceptable to rural residents. In addition to a smartphone app, this program-Make Better Choices 2-consists of personalized health coaching, accelerometer use, and financial incentives.

METHODS: We convened 4 focus groups and 16 key informant interviews with diverse community stakeholders to assess perspectives on this …

Association Between Height And Hypertension Among Us Adults: Analyses Of National Health And Nutrition Examination Survey 2007-18, Rajat Das Gupta, Maxwell Akonde, Ibrahim Hossain Sajal, Gulam Muhammed Al Kibria

Publications

Background

Previous studies that investigated association of height with prevalence and control of hypertension found mixed results. This cross-sectional study explored these associations among US adults (≥20 years).

Methods

The National Health and Nutrition Examination Survey (NHANES) 2007–18 data was analyzed. Height was measured in meters and was converted into centimeters (cm) and was further divided into quartiles: Q1 (135.3–159.2 cm), Q2 (159.3–166.2 cm), Q3 (166.3–173.6 cm), Q4 (173.7–204.5 cm). Hypertension definition of the ‘2017 American College of Cardiology/American Heart Association Guideline’ was used. Logistic regression analyses were conducted to find out the association between the dependent variable and the …

Understanding The Impact Of The Sars-Cov-2 Pandemic On Hospitalized Patients With Substance Use Disorder, Caroline King, Taylor Vega, Dana Button, Christina Nicolaidis, Jessica Gregg, Honora Englander

School of Social Work Faculty Publications and Presentations

Background: The SARS-COV-2 pandemic rapidly shifted dynamics around hospitalization for many communities. This study aimed to evaluate how the pandemic altered the experience of healthcare, acute illness, and care transitions among hospitalized patients with substance use disorder (SUD).

Methods: We performed a qualitative study at an academic medical center in Portland, Oregon, in Spring 2020. We conducted semi-structured interviews, and conducted a thematic analysis, using an inductive approach, at a semantic level.

Results: We enrolled 27 participants, and identified four main themes: 1) shuttered community resources threatened patients' basic survival adaptations; 2) changes in outpatient care increased reliance on hospitals …

Sirolimus Therapy And Follow-Up In A Patient With Severe Congenital Hyperinsulinism Following Subtotal Pancreatectomy, Qiong Chen, Yongxing Chen, Xiaohong Wang, Haihua Yang, Yingxian Zhang, Xiaojing Liu, Yun Yan, Haiyan Wei

Manuscripts, Articles, Book Chapters and Other Papers

Congenital hyperinsulinism (CHI) is the most common cause of severe, persistent hypoglycemia in neonates and infants. If the patient does not respond to medical treatment the currently available treatment is subtotal pancreatectomy, but some patients still experience severe hypoglycemia after surgery. Sirolimus, a mammalian target of rapamycin inhibitor has recently been reported to be effective in the treatment of insulinoma and CHI patients. Here we report a patient with CHI who had prolonged hypoglycemia after subtotal pancreatectomy. The patient had a heterozygous mutation in ABCC8 but was unresponsive to an optimal dose of diazoxide (15 mg/ kg/day) and octreotide (30 …

Can Early Treatment Of Twitcher Mice With High Dose Aavrh10-Galc Eliminate The Need For Bmt?, Mohammad Rafi, Paola Luzi, David A Wenger

Department of Neurology Faculty Papers

Introduction: Krabbe disease (KD) is an autosomal recessive disorder caused by mutations in the galactocerebrosidase (GALC) gene resulting in neuro-inflammation and defective myelination in the central and peripheral nervous systems. Most infantile patients present with clinical features before six months of age and die before two years of age. The only treatment available for pre-symptomatic or mildly affected individuals is hematopoietic stem cell transplantation (HSCT). In the animal models, combining bone marrow transplantation (BMT) with gene therapy has shown the best results in disease outcome. In this study, we examine the outcome of gene therapy alone.

Methods: Twitcher (twi) mice …

Shu Scripts: Stories From The Heart Of Nursing, Winter 2021, Karen Bauce Ed.

News, Magazines and Reports

No abstract provided.

Does Supplemental Regional Anesthesia Decrease Length Of Stay And Opioid Use For Patients Undergoing Head And Neck Microvascular Reconstruction?, Earl Peter Park, John Minh Le, Jordan Gigliotti, Joel Feinstein, Yedeh P. Ying, Anthony B. Morlandt

School of Dentistry Faculty Publications

Purpose: The purpose of this study was to compare length of hospital stay and opioid usage among head and neck surgery (HNS) patients treated with and without regional anesthesia for microvascular free-flap donor sites. Methods: The authors performed a retrospective cohort study for HNS patients undergoing microvascular free-flap reconstruction. The control group received no regional anesthesia. The experimental group had a regional anesthesia nerve block performed immediately before surgery. The primary outcome variable was length of stay, and the secondary outcome variable was total morphine milliequivalents. The data were analyzed using Student t tests, analysis of variance, Mann-Whitney U test, …

Remote Data Collection: How Broadband Connectivity Affected The Conversion Of Physical Performance Testing To The Remote Setting During Covid-19: A Research Assistant's Assessment, Ramyar Eslami

University Honors Theses

The GET FIT Prostate and Exercising Together trials conducted by Dr. Kerri Winters-Stone incorporate exercise intervention for cancer survivors during or after completing their therapy. Before the COVID-19 pandemic, the laboratory assessment of both studies was conducted in-person. However, the transition to remote assessment was required due to the safety precautions of COVID-19. Protocol outcomes for administering tests like the short physical performance battery (sPPB), which includes the 4m usual walk (4MW; m/s), chair stands (CS; sec), and standing balance measurements, were completed via a video conferencing interface called Cisco Webex.

Transitioning to remote testing determined the validity of remote …

Assessing Civility At An Academic Health Science Center: Implications For Employee Satisfaction And Well-Being., Lisa A Campbell, Jenna R Lafreniere, Mhd Hasan Almekdash, David D Perlmutter, Huaxin Song, Patricia J Kelly, Rohali Keesari, Kay Leigh Shannon

College of Nursing Faculty Papers & Presentations

Incivilities are pervasive among workers in healthcare institutions. Previously identified effects include deterioration of employee physical and mental health, absenteeism, burnout, and turnover, as well as reduced patient safety and quality of care. This study documented factors related to organizational civility at an academic health sciences center (AHSC) as the basis for future intervention work. We used a cross-sectional research design to conduct an online survey at four of five campuses of an AHSC. Using the Organizational Civility Scale (OCS), we assessed differences across gender, race (White and non-White) and job type (faculty or staff) in the eleven subscales (frequency …

Enteric Fever, Buddha Basnyat, Farah Naz Qamar, Priscilla Rupali, Tahmeed Ahmed, Christopher M. Parry

Department of Paediatrics and Child Health

No abstract provided.

Connected Care: The Relationship Between Infant-Caregiver Interaction & Preterm Infant Development, Amelia G. Williams

University Honors Theses

This thesis encompasses how families and healthcare workers alike can uplift preterm infants’ development in the Neonatal Intensive Care Unit. The use of positive facial expressions, skin-to-skin contact, verbalizing with the infant, quality time, and focused attention are explored to promote the preterm infant’s positive development. Additionally, this thesis includes research on optimizing the transition from hospital to home for both parents and infants.

This thesis aims to gather information that caregivers can easily reference and put into action with preterm infants. At the end of each body paragraph, the reader can promptly locate summarizing bullet points of how caregivers …