Medicine and Health Sciences Commons^™

Artificial Neural Networks Approach For Predicting Methionine Requirement In Broiler Chickens, Chanwit Kaewtapee, Charn Khetchaturat, Rattana Nukreaw, Nuttawut Krutthai, Chaiyapoom Bunchasak

The Thai Journal of Veterinary Medicine

The objective of this research was to apply artificial neural networks (ANNs) for predicting the methionine requirement in broiler chickens at day 1-10 (starter period) and day 11-21 (grower period). A total of 28 data was obtained from five hundred and sixty male broiler chicks (Ross 308), which were divided into twenty-eight pens with twenty chickens in each. Body weight was determined at days 10 and 21. A bootstrapping method was used to multiply the observations to overcome the limited data for training. A total of 280 data was obtained and divided into a training set (n = 220) and …

The Association Between Overnight Fasting And Body Mass Index In Older Adults: The Interaction Between Duration And Timing, Qian Xiao, Cici Bauer, Tracy Layne, Mary Playdon

Faculty, Staff and Student Publications

BACKGROUND: Circadian rhythms play an important role in the regulation of eating and fasting, and mistimed dietary intakes may be detrimental to metabolic health. Extended overnight fasting has been proposed as a strategy to better align the eating-fasting cycle with the internal circadian clock, and both observational and experimental studies have linked longer overnight fasting with lower body weight. However, it remains unclear if the timing of overnight fasting modifies the relationship between fasting duration and weight outcomes.

METHODS: The current study included 495 men and 499 women age 50-74 years. Dietary intake over 12 months was assessed by 24-h …

Prognostic Impact Of Single And Multiple Descriptors In Pathologically Staged T3n0m0 Nsclc, Takefumi Komiya Md, Emily Powell Phd, Shinkichi Takamori Md, Phd

PCI Publications and Projects

Introduction

T components of the current eighth edition of lung cancer American Joint Commission on Cancer (AJCC) staging assignment include size of primary tumor and others such as chest wall invasion. The role of the presence of multiple T3 descriptors in prognosis remains unknown.

Methods

Using the National Cancer Database and the AJCC seventh edition, pathologically staged (R0) N0M0 NSCLC cases diagnosed in 2010 to 2016 were analyzed. The selected cases had primary size larger than 5 cm or staged as T3 by the AJCC seventh edition despite the size of less than 5 cm. T3 descriptor status according to …

Development Of A Robust Methodology To Obtain And Assess Myogenic Precursor Cells For Their Use In Regenerative Therapies, Ricardo Lasa

Master's Theses

Peripheral arterial occlusive disease (PAOD) is characterized by buildup of atherosclerotic plaque in peripheral arteries that leads to an occlusion that can interrupt the supply of blood to the peripheral tissue, causing downstream tissue ischemia/hypoxia. PAOD is estimated to affect over 200 million patients worldwide. Current surgical revascularization treatments can be effective in about half of the patient population, leading to a significant number of patients with no treatment options beyond pharmacological intervention and lifestyle modification. The decrease in blood flow downstream of the occlusion leads to increased blood pressure gradient in the microvasculature, specifically in vessels that connect arterial …

Incidence And Pathophysiology Of Diabetes In South Asian Adults Living In India And Pakistan Compared With Us Blacks And Whites, K M Venkat Naraya, Dimple Kondal, Natalie Daya, Unjali P. Gujral, Deepa Mohan, Shivani A. Patel, Roopa Shivashankar, Ranjit Mohan Anjana, Lisa R. Staimez, Muhammad Masood Kadir

Community Health Sciences

Introduction: We compared diabetes incidence in South Asians aged ≥45 years in urban India (Chennai and Delhi) and Pakistan (Karachi), two low-income and middle-income countries undergoing rapid transition, with blacks and whites in the US, a high-income country.
Research design and methods: We computed age-specific, sex-specific and body mass index (BMI)-specific diabetes incidence from the prospective Center for Cardiometabolic Risk Reduction in South Asia Study (n=3136) and the Atherosclerosis Risk in Communities Study (blacks, n=3059; whites, n=9924). We assessed factors associated with incident diabetes using Cox proportional hazards regression.
Results: South Asians have lower BMI and waist circumference than blacks …

Role Of Contrast Enhanced Computed Tomography In Assessing Cervical Lymph Node Metastases In Oral Cavity Squamous Cell Carcinoma, Talha Ahmed Qureshi, Muhammad Wasif, Mohammad Sohail Awan, Adnan Yar Muhammad, Ainulakbar Mughal, Abdullah Ameen

Section of Otolaryngology, Head & Neck Surgery

Objective: To evaluate the diagnostic accuracy of contrast-enhanced computed tomography scan in detecting cervical nodal metastasis in oral cavity squamous cell carcinoma.
Methods: The retrospective cross-sectional study was conducted at Aga Khan University Hospital, Karachi, Pakistan. and comprised records from January 1, 2015, to October 31, 2016, of patients diagnosed with oral cavity squamous cell carcinoma and who underwent surgical resection of primary tumour along with neck dissection after having a contrast-enhanced computed tomography scan of head and neck. Diagnostic accuracy of the scans was calculated using final histopathology as the gold standard. All scans were reviewed by a consultant …

Readiness To Change And Prospective Effects Of Weight Management Programs In Pediatric Nonalcoholic Fatty Liver Disease., Voytek Slowik, Heather Wasserkrug, Ryan T. Fischer, Mark Connelly, Amanda D. Deacy, Sarah Hampl, James F. Daniel

Manuscripts, Articles, Book Chapters and Other Papers

Non-alcoholic fatty liver disease (NAFLD) is an increasing problem in pediatrics with limited treatment options. We prospectively assessed outcomes in patients managed in a hepatology clinic (HC) alone vs. those managed in combination with a multidisciplinary weight management program (MWMP). We describe each group's readiness to change at the time of NAFLD diagnosis. Patients diagnosed with NAFLD were given a modified Stages of Change Readiness and Treatment Eagerness Scale (SOCRATES) at enrollment (T1) to assess readiness to change. They were then followed at 3-9 months (T2) and at 10-15 months (T3). Linear mixed models were used to evaluate changes in …

Initial Experience In Monitoring Qt Intervals Using A Six-Lead Contactless Mobile Electrocardiogram In An Inpatient Setting., Daniel Frisch, Eitan Frankel, Darius Farzad, Md, Sang H Woo, Alan Kubey

Division of Cardiology Faculty Papers

Mobile electrocardiograms (ECGs) (mECGs) using smartphone applications are an emerging technology. In the coronavirus disease 2019 (COVID-19) era, minimizing patient contact has gained increasing importance. Additionally, increased QT/corrected QT (QTc) monitoring has concurrently been required. The KardiaMobile 6L ECG device, cleared by the United States Food and Drug Administration (FDA) for recording ECGs, along with the KardiaStation tablet application is a platform (AliveCor, Mountain View, CA, USA) that addresses these two issues. A team of residents, fellows, hospitalists, and cardiologists identified inpatients in need of QT/QTc interval monitoring to pilot the adoption of a system composed of a KardiaMobile 6L …

Does The Management Of Compassion Fatigue In The Healthcare Setting Decrease Nurse Turnover: An Integrative Review, Barbara Fulcher Williams

Doctoral Dissertations and Projects

Healthcare systems are rapidly changing and with the increased age of the baby boomers, and shortage of nurses, and COVID-19, there is a rapid growth in compassion fatigue within the nursing community. More than 22% of nurses in direct patient care roles report experiencing emotional exhaustion. This results in negative consequences, reduced productivity, workplace violence, and poor patient care. Does the management of compassion fatigue in the healthcare setting decrease nurse turnover? This was an integrative review of the literature, utilizing 15-20 articles using Melnyk framework for evaluation. The variables addressed included the emotional state with negative psychological and physical …

J Mich Dent Assoc March 2021

The Journal of the Michigan Dental Association

Every month, The Journal of the Michigan Dental Association brings news, information, and features about Michigan dentistry to our state's oral health community and the MDA's 6,200+ members. No publication reaches more Michigan dentists!

In this issue, the reader will find the following original content:

• A cover story, “Vaccination by Dentists: Integrating Vaccination into Dental Practice”.
• A feature article on “Creating Opportunities for HPV Awareness and Prevention in Dental Health Care Settings”.
• The feature article, “MDA Legislative Advocacy 2021: What We’ve Done and What’s to Come”.
• “How COVID-19 Has Impacted Michigan Dentists”, a feature article.
• News you need, Editorial and …

Significant Stakeholders: Toward An Agile Knowledge Management System In The Time Of Coronavirus Crisis, Yaojie Li, Yi Zhou, Thomas Stafford, Xuan Wang

Information Systems Faculty Publications

Effective crisis response requires sophisticated knowledge management in organizations. Agile systems development capabilities for such crisis response systems are important, particularly for purposes of tailoring a crisis-oriented knowledge management system to a rapidly shifting threat landscape. We propose an architecture for achieving both of these ends in the form of an Agile Crisis Management System involving three specific stakeholders, and we discuss the steps, outcomes, and implications of such a system.

Re-Entry Housing Collaborative Final Evaluation Report, Monique Gill, Ritu Ghosal, Kyle Jones, Aisha K Gilmore

View All

No abstract provided.

Brain Candy: Wayne State University School Of Medicine Journal Of Arts And Culture, 8th Edition, Wayne State University School Of Medicine Gold Humanism Honor Society

Gold Humanism Honor Society

Brain Candy incorporates paintings, written pieces, and poetry from all the medical classes at Wayne State University School of Medicine to shed light on the creative process in medicine, the city of Detroit, and the experiences of health care providers. The first edition of Brain Candy was published online and in print in 2009, produced by a generous grant by the Gold Humanism Honor Society (GHHS). The edition featured poetry, nonfiction, short fiction, and different types of artwork. With generous funding support from alumnus Dr. Tom Janisse, Class of 1975, the journal continues to be in print since 2009.

Mice Pups Breastfed By Foster Mothers Whose Breast Milk Contains Plasmodium Falciparum Recombinant Se36 Antigen Develop Specific Antibodies, Margaret Mendi Njoroge, Victor Irungu Mwangi, Tonny Jimmy Owalla, Hastings Ozwara, Thomas G. Egwang

All Peer-Reviewed Publications

Intranasal instillation of SE36, a malaria vaccine candidate antigen, in lactating BALB/c strain (derived from the Bagg and albino laboratory inbred mice) female mice resulted in the appearance of the antigen in breast milk as demonstrated by sandwich ELISA and Western blot. Pups born of immunologically naive mice and breastfed on lactating foster mothers exposed intranasally to SE36 developed IgG anti-SE36 antibodies. These data demonstrate that maternal immunization in mice by this route in lactating mothers can result in active immunization of offspring via ingestion of breast milk containing antigen. If confirmed in a nonhuman primate model and in human …

Are The Current Animal Trypanosomiasis Management Methods In Kenya Complementary Or Substitutes? Evidence From Kwale County, Arnold Lumumbah Musungu, David Jakinda Otieno, Beatrice Wambui Muriithi, Rose Nyikal, Daniel Masiga, Michael Nyanganga Okal

All Peer-Reviewed Publications

African animal trypanosomiasis (AAT) and its vectors, mainly tsetse, are a major constraint to livestock production in sub-Saharan Africa (SSA). Control efforts have been ongoing for decades, but finding a sustainable solution remains a major concern. This paper assessed the complementarity and substitutability of existing AAT management methods to inform policies toward an integrated approach. A multivariate probit (MVP) analytical technique was used to model interrelationships in the control methods from 308 randomly selected livestock keepers. The results show that the current AAT control methods are complementary and not substitutes. Furthermore, the number of years of formal education, household size, …

Interprofessional Education Towards Interprofessional Practice: A Mixed-Methods Exploration Of Respiratory Care Students And Therapists’ Perceptions, Ziyad Al Nufaiei

Seton Hall University Dissertations and Theses (ETDs)

Context: Respiratory care (RC) is a health-care discipline that specializes in providing

treatment for patients with acute and chronic cardiopulmonary abnormalities. The actual practice of respiratory care has changed dramatically since its inception. Today, RCs possess a strong skill base and an expansive depth of knowledge, which enables them to provide safe,team-based, evidence-based effective care for patients. The Commission on Accreditation for Respiratory Care (CoARC) has recently required that RC programs nationwide include interprofessional education (IPE) as an accreditation standard to encourage the goal of promoting interprofessional practice (IPP).

Objective: To explore perceptions of RC students, faculty, and practicing professionals …

A Systematic Review On Improving Implementation Of The Revitalised Integrated Disease Surveillance And Response System In The African Region: A Health Workers' Perspective, Arthur K.S. Ng'etichi, Kuku Voyi, Ruth C. Kirinyet, Clifford M. Mutero

All Peer-Reviewed Publications

Background The revised integrated disease surveillance and response (IDSR) guidelines adopted by African member states in 2010 aimed at strengthening surveillance systems critical capacities. Milestones achieved through IDSR strategy implementation prior to adopting the revised guidelines are well documented; however, there is a dearth of knowledge on the progress made post-adoption. This study aimed to review key recommendations resulting from surveillance assessment studies to improve implementation of the revitalised IDSR system in the African region based on health workers' perspectives. The review focused on literature published between 2010 and 2019 post-adopting the revised IDSR guidelines in the African region. Methods …

Relationship Between Sexual Activity, Contraceptive Utilization And Biopsychosocial Characteristics Among Homeless Adolescents, Brittany Gaudet Bs, Msph, Nina Liu Bs, Jeffrey Downen Bs, Ms, Taylor Jarvill Ba, Cecilia E. Zemanek Bs, Michele N. Karn Bs, Hoonani M. Cuadrado Mspas, Pa-C, Joanne Quiñones Md, Msce

USF-LVHN SELECT

No abstract provided.

In Vivo Transplantation Of Human Intestinal Organoids Enhances Select Tight Junction Gene Expression, Mariaelena A Boyle, David J Sequeira, Eoin P Mcneill, Zachary K Criss, Noah F Shroyer, Allison L Speer

Faculty, Staff and Student Publications

BACKGROUND: Short bowel syndrome is a potentially fatal condition with inadequate management options. Tissue-engineered small intestine (TESI) is a promising solution, but confirmation of TESI function will be crucial before human application. We sought to define intestinal epithelial barrier function in human intestinal organoid (HIO)-derived TESI.

MATERIALS AND METHODS: HIOs were generated in vitro from human embryonic stem cells. After 1 mo, HIOs were collected for analysis or transplanted into the kidney capsule of immunocompromised mice. Transplanted HIOs (tHIOs) were harvested for analysis at 4 or 8 wk. Reverse transcription quantitative polymerase chain reaction and immunofluorescent staining were performed for …

Development Of 3d In Vitro Tissue Models For The Analysis Of Solar Radiation Damage Of Skin, Ulises Lopez Gonzalez

Doctoral

The aim of this work was to investigate changes to the molecular composition and conformation of HaCaT cells as a result of simulated solar radiation in a 3D in vitro skin model by Raman spectroscopy. The process to achieve this goal was performed in three main stages: (1) optimisation of the working concentration and volume of two 3D membranes, used as a structural support in the skin model; (2) the construction of the 3D in vitro skin model and; (3) the investigation of the dose-dependent effects of solar radiation on HaCaT cells in the skin model in comparison with the …

Does Hand Involvement In Systemic Sclerosis Limit Completion Of Patient-Reported Outcome Measures?, Tracy M Frech, John M Vanburen, Emily Startup, Shervin Assassi, Elana J Bernstein, Flavia V Castelino, Lorinda Chung, Chase Correia, Jessica K Gordon, Faye N Hant, Laura Hummers, Dinesh Khanna, Nora Sandorfi, Ami A Shah, Victoria K Shanmugam, Virginia Steen, Luke Evnin

Faculty, Staff and Student Publications

The objective of this analysis is to examine whether the severity of systemic sclerosis (SSc)-hand involvement influences patient-reported outcome measure (PROM) completion rate in a US cohort of early disease. Participants included SSc patients with less than 5 years disease duration consented and enrolled in the Collaborative, National, Quality, and Efficacy Registry (CONQUER) between June 2018 and December 2019. Participants' socio-demographics, hand clinical features (severe modified Rodnan skin score, presence of small joint contractures, acro-osteolysis, calcinosis, and digital ulcers), and completion rates of seven PROMs including a Resource Use Questionnaire were analyzed. Cohort characteristics and baseline PROM completion were evaluated. …

Review Of Machine Learning Techniques For Mosquito Control In Urban Environments, Ananya Joshi, Clayton Miller

Research Collection College of Integrative Studies

Machine learning (ML) techniques excel at forecasting, clustering, and classification tasks, making them valuable for various aspects of mosquito control. In this literature review, we selected 120 papers relevant to the current state of ML for mosquito control in urban settings. The reviewed work covers several different methodologies, objectives, and evaluation criteria from various environmental contexts. We first divided the existing papers into geospatial, visual, or audio categories. For each category, we analyzed the machine learning pipeline, from dataset creation to model performance. We conclude with a discussion of the challenges and opportunities for further research. While the reviewed ML …

Perceptions Of Migrant And Seasonal Head Start Parents About Childhood Vision Care Utilization, Felicia R. Thomas

Electronic Theses and Dissertations

The benefits of pediatric vision screening for very young children is not a new concept. However, not all children receive this valuable preventative intervention, or they do not receive an evaluation or examination to rule out or treat common visual refractive errors. This Doctor of Nursing Project sought to identify factors that impact a parent’s failure to follow up on recommendations for further evaluation or treatment following their child’s failed vision screening. The project utilized a phenomenological study to assess Migrant and Seasonal Head Start parents’ perceptions about their perceptions of the need for preventative vision screening and care. Three …

A Systematic Review Of Acuity-Based Staffing In Acute Healthcare Environments, Demitria Idella Stafford

Electronic Theses and Dissertations

Nursing leadership is responsible for considering the equity of patient care assignments when providing nursing care. Nursing leadership is responsible for assuring the delivery of patient care assignments with the intent to offer nurses an unbiased, evenly distributed patient load. Effective distribution of patient care assignments ensures patients receive the safest, most efficient, and highest quality of care. The purpose of this project was to provide nursing leadership with an executive summary of a systematic review of evidence-based research on the structure and process of making patient care assignments, and it provided evidence on how those patient care assignments affect …

Applying 'Earable' Inertial Sensing For Real-Time Head Posture Detection, Meeralakshmi Radhakrishnan, Kushaan Misra, V. Ravichandran

Research Collection School Of Computing and Information Systems

We explore the use of personal earable devices for detecting and correcting incorrect head postures, which can trigger the medical condition of “Forward Head Posture”. We demonstrate how the gyroscope and accelerometer sensors on an earable device can be used to detect episodes where the head is rotated sufficiently forward, for significantly long durations (> 30secs), and then generate suitable audio-based corrective feedback. Using a small-scale preliminary study, we show that our approach is promising as it provides both high precision (100%) & recall (89%).

The New Normal Of Social Psychology In The Face Of The Covid-19 Pandemic: Insights And Advice From Leaders In The Field, Kim Pong Tam, Angela K. Y. Leung, Sammyh Khan

Research Collection School of Social Sciences

Revisiting the history of social psychology, one noticeable trend is that the agenda of social psychologists is interwoven with events that happen in society and the world (Ross et al., 2010). For example, the Holocaust during World War II stimulated social psychologists’ interest in ethnocentrism, aggression, and obedience, just as increasing globalization became one of the impetuses for investigations into the role of culture in human behaviour, and hence the emergence of cultural and cross‐cultural psychology. Considering its immensity, we believe that the COVID‐19 pandemic will likely be a trigger for profound and consequential changes in social psychology (Khazaie & …

Income Inequality And Opioid Prescribing Rates: Exploring Rural/Urban Differences In Pathways Via Residential Stability And Social Isolation, Tse-Chuan Yang, Seulki Kim, Carla Shoff

Department of Sociology: Faculty Publications

While opioid prescribing rates have drawn researchers’ attention, little is known about the mechanisms through which income inequality affects opioid prescribing rates and even less focuses on whether there is a rural/urban difference in mediating pathways. Applying mediation analysis techniques to a unique ZIP code–level dataset from several sources maintained by the Centers for Medicare and Medicaid Services, we explicitly examine two mechanisms through residential stability and social isolation by rural/urban status and find that (1) income inequality is not directly related to opioid prescribing rates, but it exerts its influence on opioid prescribing via poor residential stability and elevated …

Cultures Of Practice: Specialty-Specific Differences In End-Of-Life Conversations., Andre Morales, Kevan C Schultz, Shasha Gao, Alan Murphy, Amber E Barnato, Joseph B Fanning, Daniel E Hall

Ambulatory and Primary Care Articles

No abstract provided.

The Effect Of Prolonged Pre-Operative Halo Gravity Traction For Severe Spinal Deformities On The Cervical Spine Radiographs, Kawdwo P. Yankey, Henry Ofori Duah, Cristina Sacramento-Dominguez, Henry O. Tutu, Mabel Adobea Owiredu, Rufai Mahmud, Irene Wulff, Gerhard Ofori-Amankwah, Harry Akoto, Oheneba Boachie-Adjei, Focos Spine Research Group

College of Nursing Faculty Research and Publications

Study Design:

Retrospective review of consecutive series.

Objective:

The study sought to assess the effect of prolonged pre-operative halo gravity traction (HGT) on the c-spine radiographs

Methods:

Data of 37 pediatric and adult patients who underwent ≥ 12wks pre-op HGT prior to definitive spine surgery from 2013-2015 at a single site in West Africa was reviewed. Radiographic assessment of the c-spine including ADI, SVA and C2-C7 Lordosis were done at pre HGT and at 4 weekly intervals. Paired T-Test was performed to evaluate changes in these parameters during HGT.

Results:

37pts, 18/19 (F/M). Average age 18.2yrs. Diagnoses: 22 idiopathic, 6 …

The National Covid Cohort Collaborative (N3c): Rationale, Design, Infrastructure, And Deployment, Melissa A Haendel, Philip R O Payne, Et Al.

2020-Current year OA Pubs

OBJECTIVE: Coronavirus disease 2019 (COVID-19) poses societal challenges that require expeditious data and knowledge sharing. Though organizational clinical data are abundant, these are largely inaccessible to outside researchers. Statistical, machine learning, and causal analyses are most successful with large-scale data beyond what is available in any given organization. Here, we introduce the National COVID Cohort Collaborative (N3C), an open science community focused on analyzing patient-level data from many centers.

MATERIALS AND METHODS: The Clinical and Translational Science Award Program and scientific community created N3C to overcome technical, regulatory, policy, and governance barriers to sharing and harmonizing individual-level clinical data. We …