Medicine and Health Sciences Commons^™

Smartphone-Based Prediction Model For Postoperative Cardiac Surgery Outcomes Using Preoperative Gait And Posture Measures, Rahul Soangra, Thurmon Lockhart

Physical Therapy Faculty Articles and Research

Gait speed assessment increases the predictive value of mortality and morbidity following older adults’ cardiac surgery. The purpose of this study was to improve clinical assessment and prediction of mortality and morbidity among older patients undergoing cardiac surgery through the identification of the relationships between preoperative gait and postural stability characteristics utilizing a noninvasive-wearable mobile phone device and postoperative cardiac surgical outcomes. This research was a prospective study of ambulatory patients aged over 70 years undergoing non-emergent cardiac surgery. Sixteen older adults with cardiovascular disease (Age 76.1 ± 3.6 years) scheduled for cardiac surgery within the next 24 h were …

Prediction Of Obstructive Sleep Apnea Using Fast Fourier Transform Of Overnight Breath Recordings, Nicole L. Molin, Clifford Molin, Rohan J. Dalpatadu, Ashok K. Singh

Mathematical Sciences Faculty Research

The objective of this study is to address the problem of predicting the risk of obstructive sleep apnea (OSA) from overnight breath recordings collected by a subject using a smartphone or an iPhone. The dataset used in this study was collected at a health care facility and consists of breathing amplitudes of 42 subjects using the smart phone App ZeeAppnea. A total of four data mining multi-level classifiers are used on the Fast Fourier Transform (FFT) of each time series, and prediction accuracies are computed. The Random Forest (RF) and the Support Vector Machine (SVM) classifiers yielded the best results, …

Lawmakers' Use Of Scientific Evidence Can Be Improved, D Max Crowley, J Taylor Scott, Elizabeth C Long, Lawrie Green, Azaliah Israel, Lauren Supplee, Elizabeth Jordan, Kathryn Oliver, Shannon Guillot-Wright, Brittany Gay, Rachel Storace, Naomi Torres-Mackie, Yolanda Murphy, Sandra Donnay, Jenna Reardanz, Rebecca Smith, Kristina Mcguire, Elizabeth Baker, Ana Antonopoulos, Mary Mccauley, Cagla Giray

Faculty, Staff and Student Publications

Core to the goal of scientific exploration is the opportunity to guide future decision-making. Yet, elected officials often miss opportunities to use science in their policymaking. This work reports on an experiment with the US Congress-evaluating the effects of a randomized, dual-population (i.e., researchers and congressional offices) outreach model for supporting legislative use of research evidence regarding child and family policy issues. In this experiment, we found that congressional offices randomized to the intervention reported greater value of research for understanding issues than the control group following implementation. More research use was also observed in legislation introduced by the intervention …

Racial Disparities In Post-Acute Home Health Care Referral And Utilization Among Older Adults With Diabetes, Jamie Smith, Olga Jarrín, Haiqun Lin, Tina Dharamdasani, Jennifer Tsui, Charlotte Thomas-Hawkins

College of Nursing Faculty Papers & Presentations

Racial and ethnic disparities exist in diabetes prevalence, health services utilization, and outcomes including disabling and life-threatening complications among patients with diabetes. Home health care may especially benefit older adults with diabetes through individualized education, advocacy, care coordination, and psychosocial support for patients and their caregivers. The purpose of this study was to examine the association between race/ethnicity and hospital discharge to home health care and subsequent utilization of home health care among a cohort of adults (age 50 and older) who experienced a diabetes-related hospitalization. The study was limited to patients who were continuously enrolled in Medicare for at …

The Emerging Global Tobacco Treatment Workforce: Characteristics Of Tobacco Treatment Specialists Trained In Council-Accredited Training Programs From 2017 To 2019, Christine E. Sheffer, Abdulmohsen Al-Zalabani, Andrée Aubrey, Rasha Bader, Claribel Beltrez, Susan Bennett, Ellen Carl, Caroline Cranos, Audrey Darville, Jennifer Greyber, Maher Karam-Hage, Feras Hawari, Tresza Hutcheson, Victoria Hynes, Chris Kotsen, Frank Leone, Jamie Mcconaha, Heather Mccary, Crystal Meade, Cara Messick

Nursing Faculty Publications

Tobacco use is projected to kill 1 billion people in the 21st century. Tobacco Use Disorder (TUD) is one of the most common substance use disorders in the world. Evidence-based treatment of TUD is effective, but treatment accessibility remains very low. A dearth of specially trained clinicians is a significant barrier to treatment accessibility, even within systems of care that implement brief intervention models. The treatment of TUD is becoming more complex and tailoring treatment to address new and traditional tobacco products is needed. The Council for Tobacco Treatment Training Programs (Council) is the accrediting body for Tobacco Treatment Specialist …

Brucella Melitensis-Induced Transaminitis., Rajesh Essrani Md, Anastasia Shnitser Md

Department of Medicine

Brucellosis is infrequently reported in the United States and is mostly an occupational hazard among workers engaged in livestock raising and processing. It is a systemic infectious disease and can involve the liver in varying ways, ranging from benign subclinical increases in serum aminotransferase levels to ominous chronic suppurative disease. It is endemic in many countries, primarily those of the Mediterranean region. It is usually treated with antibiotics. We present a case of a 37-year-old female who developed

Nutrition And Chronic Pain, Elise Withers, Mateja R. Savoie-Roskos, Riley Samples, Maren Wright Voss

All Current Publications

The internet is full of information about anti-inflammatory diets, foods, and supplements claiming to prevent or alleviate chronic pain. For those who struggle with chronic pain, sound dietary advice is essential to improve intake and ultimately decrease pain (Arranz et al., 2010). However, it’s important to note that research showing the impact of specific foods on health and the immune system is currently limited; therefore, these claims should be interpreted with caution (Elma et al., 2020; Harvard Health, 2018). This fact sheet will cover (1) how inflammation affects chronic pain and (2) how eating a well-balanced diet may help reduce …

Severe Acute Respiratory Syndrome Coronavirus 2-Induced Acute Aortic Occlusion: A Case Report, Artem Minalyan, Franklin L. Thelmo, Vincent Chan, Stephanie Tzarnas, Faizan Ahmed

Department of Medicine Faculty Papers

Background: Severe acute respiratory syndrome coronavirus 2 infection can lead to a constellation of viral and immune symptoms called coronavirus disease 2019. Emerging literature increasingly supports the premise that severe acute respiratory syndrome coronavirus 2 promotes a prothrombotic milieu. However, to date there have been no reports of acute aortic occlusion, itself a rare phenomenon. We report a case of fatal acute aortic occlusion in a patient with coronavirus disease 2019.

Case report: A 59-year-old Caucasian male with past medical history of peripheral vascular disease presented to the emergency department for evaluation of shortness of breath, fevers, and dry cough. …

Glucagon Blockade Restores Functional Β-Cell Mass In Type 1 Diabetic Mice And Enhances Function Of Human Islets, May-Yun Wang, E Danielle Dean, Ezekiel Quittner-Strom, Yi Zhu, Kamrul H Chowdhury, Zhuzhen Zhang, Shangang Zhao, Na Li, Reshing Ye, Young Lee, Yiyi Zhang, Shiuhwei Chen, Xinxin Yu, Derek C Leonard, Greg Poffenberger, Alison Von Deylen, S Kay Mccorkle, Amnon Schlegel, Kyle W Sloop, Alexander M Efanov, Ruth E Gimeno, Philipp E Scherer, Alvin C Powers, Roger H Unger, William L Holland

Faculty, Staff and Students Publications

We evaluated the potential for a monoclonal antibody antagonist of the glucagon receptor (Ab-4) to maintain glucose homeostasis in type 1 diabetic rodents. We noted durable and sustained improvements in glycemia which persist long after treatment withdrawal. Ab-4 promoted β-cell survival and enhanced the recovery of insulin+ islet mass with concomitant increases in circulating insulin and C peptide. In PANIC-ATTAC mice, an inducible model of β-cell apoptosis which allows for robust assessment of β-cell regeneration following caspase-8–induced diabetes, Ab-4 drove a 6.7-fold increase in β-cell mass. Lineage tracing suggests that this restoration of functional insulin-producing cells was at least partially …

Discovery And Characterization Of Bromodomain 2-Specific Inhibitors Of Brdt, Zhifeng Yu, Angela F Ku, Justin L Anglin, Rajesh Sharma, Melek Nihan Ucisik, John C Faver, Feng Li, Pranavanand Nyshadham, Nicholas Simmons, Kiran L Sharma, Sureshbabu Nagarajan, Kevin Riehle, Gundeep Kaur, Banumathi Sankaran, Marta Storl-Desmond, Stephen S Palmer, Damian W Young, Choel Kim, Martin M Matzuk

Faculty, Staff and Students Publications

Bromodomain testis (BRDT), a member of the bromodomain and extraterminal (BET) subfamily that includes the cancer targets BRD2, BRD3, and BRD4, is a validated contraceptive target. All BET subfamily members have two tandem bromodomains (BD1 and BD2). Knockout mice lacking BRDT-BD1 or both bromodomains are infertile. Treatment of mice with JQ1, a BET BD1/BD2 nonselective inhibitor with the highest affinity for BRD4, disrupts spermatogenesis and reduces sperm number and motility. To assess the contribution of each BRDT bromodomain, we screened our collection of DNA-encoded chemical libraries for BRDT-BD1 and BRDT-BD2 binders. High-enrichment hits were identified and resynthesized off-DNA and examined …

The Iterative Model Of Ethical Analysis For Large-Scale Implementation Of Ict Solutions, Carina Dantas

Translational Medicine @ UniSa

This manuscript presents a model and the methodology to understand and define the ethical management of the large-scale implementation of ICT solutions for Active and Healthy Ageing. Based on project expertise, including experience from the Pharaon project Horizon2020, this model includes an understanding of the main ethical challenges and the development of the necessary guidelines, measures, and tools for different stakeholder profiles. This model extends beyond conventional ethical guidelines, providing a methodology to actively discuss ethical and societal challenges within a project based on interactive and iterative dialogue between the entire value-chain of stakeholders. One of the cornerstones in the …

Beyond The Competency Model Of Therapist Trainings - Developing Expertise Through Deliberate Practice, Daryl Mahon Ba, Ma

Counseling and Family Therapy Scholarship Review

The purpose of the present paper is to describe how Deliberate Practice (DP) can be used to assist individual therapists develop expertise and improve their ability to effect change in their clients' psychotherapy outcomes. The author provides a targeted review of this literature and articulates a method of training therapists based on this relatively new and exciting concept. The initial training of psychotherapists represents an important milestone in an often lifelong career and one that is marked with a continuous professional development trajectory. While it is particularly important to achieve competency in many foundational skills and techniques during training, this …

Using Ambiguous Loss To Address Perceived Control During The Covid-19 Pandemic, Rosemary A. Leone

Counseling and Family Therapy Scholarship Review

The concepts of ambiguous loss and perceived control will be used to explore ways to embrace the unknown during COVID-19. By defining COVID-19 as an ambiguous loss, effective therapeutic interventions emerge that can guide clinicians in creating lasting change amidst widespread uncertainty. Four ambiguous loss interventions will be proposed to alleviate the distress of living in fearful semi-isolation for an unknown period of time. In paradoxically embracing uncertainty, clients can create new hope in the context of a global pandemic. New hope is the ideal outcome when coping with ambiguous loss. In literature on ambiguous loss, the concept of new …

An Essay Concerning The Substance Of Counseling, Lance Kair

Counseling and Family Therapy Scholarship Review

Our modern world appears to lack a way to find truth. Philosophically, this problem is formulated in a manner of knowing which never gets beyond the subject of the universe; even objectivity in the universe is arguable. The effort called empirical science then gives us conclusions that regularly perpetuate an unstable world. Due to this real subjective empirical constraint, the usual approach to therapeutic Counseling offers methods focused on the individual obtaining skills and conceptions that function to mitigate the apparent and ubiquitous problem of modernity. Empirical science, whether it be physical, biological or phenomenal, has left us with only …

Clash Of Values: Workplace Bullying And Moral Injury, Jarl B. Anderson Ma, Mftc

Counseling and Family Therapy Scholarship Review

Moral injury is a psychological construct developed in military context, and although it has been expanded to include specific occupational fields outside of the military, it has not yet been proposed as an outcome of workplace bullying. Employees may experience moral injury when their personal values and the legitimate values of the workplace clash with unacknowledged shadow values during incidents of workplace bullying. Workplace bullying could be considered a potentially morally injurious event (PMIE) because it is transgressive, it is asymmetric, and it involves high stakes: livelihood and identity are at risk. Regarding counseling considerations, the use of ritual has …

Observations On The Relationship Between Resilience And Mindfulness, Jason N. Linder Psy. D., Jay A. Mancini

Counseling and Family Therapy Scholarship Review

In the last three decades, mindfulness and resilience have received extensive scholarly attention. Research has burgeoned and they have both become “buzz words” in the social sciences and mental health fields. That said, they are often presented as unrelated qualities, skills, or states, and few studies and texts have examined their linkages and/or how they complement each other. Masten’s (2001, 2009) seminal papers and subsequent book (2014) that presented resilience as “ordinary magic” have had large impacts on resilience scholarship, bringing forth that resilience is much more of a common human occurrence and proclivity than previously considered. In this paper, …

Stem Mental Wellness Research, Hannah R. Anderson, Amber Stitziel Pareja

Publications & Research

NCSSS and IMSA conducted a survey to gather information regarding how NCSSS member schools handle carious aspects of student mental wellness and mental illness as well as the resources and programming available to address concerns in these areas.

Download The 2020 NCSSS Student Mental Health Survey: A Synopsis

Integrating Policies, Systems, And Environments (Pse) Work Into Fcs Extension Programming: Lessons Learned From A Multi-State Training, Lisa T. Washburn, Heather Norman-Burgdolf, Karen L. Franck, Lauren E. Kennedy, Christopher T. Sneed

Dietetics and Human Nutrition Faculty Publications

Public health efforts have emphasized changes to policies, systems and environments (PSEs) to improve health behaviors for individuals and communities. Extension has increasingly emphasized these approaches, particularly for work of Family and Consumer Sciences (FCS) agents. In part, this emphasis on PSEs in Extension has been driven by SNAP-Ed and other federally funded initiatives, such as the Centers for Disease Control and Prevention (CDC) High Obesity Programs (HOP). However, broader adoption and implementation of PSEs at the local level has lagged in some states for various reasons. These include limited understanding about PSE interventions and how this work fits with …

Wellness Through Answers News V36:No.2 March-April 2021, Wendy Urciuoli

Articles - Patient Care

No abstract provided.

Wellness Through Answers News V36:No.2 March-April 2021, Wendy Urciuoli

Articles - Patient Care

No abstract provided.

Effectiveness Of A Preterm Home Care Program (Phcp) On Parent Infant Interaction Among Mothers Of Preterms And The Developmental Outcomes Of The Preterms In Kasturba Hospital, Manipal Karnataka., E. Binu Margaret

Manipal College of Nursing, Manipal Theses and Dissertations

No abstract provided.

Cities, Covid-19, And The New Normal, Singapore Management University

Perspectives@SMU

As cities recover and reorganise post-pandemic, policymakers should take into consideration how communities’ mobility, livability, security and sociability are affected

Corneal Nonmyelinating Schwann Cells Illuminated By Single-Cell Transcriptomics And Visualized By Protein Biomarkers., Paola Bargagna-Mohan, Gwendolyn Schultz, Bruce Rheaume, Ephraim F Trakhtenberg, Paul Robson, Sonali Pal-Ghosh, Mary Ann Stepp, Katherine S Given, Wendy B Macklin, Royce Mohan

Anatomy and Regenerative Biology Faculty Publications

No abstract provided.

Australian General Practice Training Program: National Report On The 2020 National Registrar Survey, Rebecca Taylor, Leyna Clarke, Ali Radloff

Higher education research

The Australian General Practice Training National Registrar Survey (AGPT NRS) is an annual, national survey of GP registrars currently training in the AGPT program. It collects information via an online questionnaire about registrar satisfaction, experience and future career plans. It also collects information about registrars’ demographics and training contexts and other aspects of their training experience. This survey is part of the Department of Health’s (the Department) monitoring and quality improvement activities. From October 12 to December 9, 2020, the Australian Council for Educational Research (ACER) administered the AGPT NRS to registrars enrolled in active training on the AGPT program …

Rap1a Overlaps The Age/Rage Signaling Cascade To Alter Expression Of Α‐Sma, P‐Nf‐Κb, And P‐Pkc‐Ζ In Cardiac Fibroblasts Isolated From Type 2 Diabetic Mice, Stephanie D. Burr, James A. Stewart

Faculty and Student Publications

Cardiovascular disease, specifically heart failure, is a common complication for individu-als with type 2 diabetes mellitus. Heart failure can arise with stiffening of the left ventricle, which can be caused by “active” cardiac fibroblasts (i.e., myofibroblasts) remodeling the extracellular matrix (ECM). Differentiation of fibroblasts to myofibroblasts has been demonstrated to be an outcome of AGE/RAGE signaling. Hyperglycemia causes advanced glycated end products (AGEs) to accu-mulate within the body, and this process is greatly accelerated under chronic diabetic conditions. AGEs can bind and activate their receptor (RAGE) to trigger multiple downstream outcomes, such as altering ECM remodeling, inflammation, and oxidative stress. …

Design Of Topical Ocular Ciprofloxacin Nanoemulsion For The Management Of Bacterial Keratitis, Ahmed Adel Ali Youssef, Chuntian Cai, Narendar Dudhipala, Soumyajit Majumdar

Faculty and Student Publications

Bacterial keratitis (BK) is a critical ocular infection that can lead to serious visual disability. Ciprofloxacin (CIP), moxifloxacin (MOX), and levofloxacin (LFX) have been accepted as monothera-pies by the US Food and Drug Administration for BK treatment. CIP is available commercially at 0.3% w/v concentration as an ophthalmic solution and as an ointment for ocular delivery. Because of solubility issues at physiological pH, CIP precipitation can occur at the corneal surface post instillation of the solution dosage form. Consequently, the ocular bioavailability of CIP is reduced. The ointment dosage form is associated with side effects such as blurred vision, itching, …

Dental Practice Success Special Issue: Financial Foundations For The New Dentist (March 2021), American Dental Association, Publishing Division

Dental Practice Success

No abstract provided.

Return To Play Rates After Ulnar Nerve Transposition And Decompression Surgery: A Retrospective Analysis., Christopher J Hadley, Anant Dixit, John Kunkel, Alex E White, Michael G Ciccotti, Steven B Cohen, Christopher C Dodson

Orthopedic Surgery Resident Research

Background: Medial elbow pain is a common complaint in overhead throwing athletes. The throwing motion places repetitive tensile and compressive forces on the elbow resulting in significant stress across the ulnohumeral joint. This stress can result in soft-tissue, ligamentous, and ulnar nerve injury. The purpose of this study was to retrospectively investigate the clinical findings and outcomes, including return to play rates, of patients who underwent ulnar nerve transposition surgery for isolated ulnar neuritis.

Methods: Throwing athletes who underwent isolated, primary ulnar nerve transposition surgery over an eight-year period, 2009 to 2017, were identified and included in our analysis. Nonthrowing …

The Effects Of Administrative Support On Registered Nurse Well-Being During The Covid-19 Pandemic, Cassandra Fox

The Eleanor Mann School of Nursing DNP Capstone Projects

Attention to the well-being of nurses is necessary to ensure the healthcare system can operate effectively, particularly during the COVID-19 pandemic. The workplace environment and support from nursing leadership strongly contribute to nurses’ well-being. Currently, there is little evidence on the effect nursing leadership has on nurses’ well-being during the COVID-19 pandemic. This DNP clinical inquiry project sought to learn more about the effects of caring leadership behaviors on nurses’ well-being during the COVID-19 pandemic. A survey composed of questions from previously validated and reliable surveys used in the field of nursing was used to collect data. Neuman’s systems theory …

New Dentist News (March 2021), Ada Committee On The New Dentist

New Dentist News

New Dentist News offers timely information on scientific, social, educational, political and economic developments affecting new dentists. This collection is historical and items may not reflect current standards. For up-to-date information contact the ADA. The New Dentist News was alternately titled ADA Lifeline, 1997-June 2001.