Medicine and Health Sciences Commons^™

Development And Validation Of A Measure Of Birth-Related Ptsd For Fathers And Birth Partners: The City Birth Trauma Scale (Partner Version), Rebecca Webb, Ann M. Smith, Susan Ayers, Daniel B. Wright, Alexandra Thornton

Educational Psychology, Leadership, and Higher Education Faculty Research

Research suggests that some fathers and birth partners can experience post-traumatic stress disorder (PTSD) after witnessing a traumatic birth. Birth-related PTSD may impact on many aspects of fathers’ and birth partners’ life, including relationship breakdown, self-blame and reducing plans for future children. Despite the potential impact on birth partners’ lives there is currently no measure of birth-related PTSD validated for use with birth partners. The current study therefore adapted the City Birth Trauma Scale for use with birth partners. The City Birth Trauma Scale (Partner version) is a 29-item questionnaire developed to measure birth-related PTSD according to DSM-5 criteria: stressor …

Downregulation Of Mmp1 Expression Mediates The Anti-Aging Activity Of Citrus Sinensis Peel Extract Nanoformulation In Uv Induced Photoaging In Mice, Dalia Attia, Reham Amer, Shahira Ezzat, Nora Aborehab, Mai Ragab, Dalia Mohamed, Amira Hashad, Maha Salama, Mahitab El Bishbishy

Pharmacy

Aging of the skin is a complicated bioprocess that is affected by constant exposure to ultraviolet irradiation. The application of herbal-based anti-aging creams is still the best choice for treatment. In the present study, Citrus sinensis L. fruit peels ethanolic extract (CSPE) was formulated into lipid nanoparticles (LNPs) anti-aging cream. Eight different formulations of CSEP-LNPs were prepared and optimized using 23 full factorial designs. In vivo antiaging effect of the best formula was tested in Swiss albino mice where photo-aging was induced by exposure to UV radiation. HPLC-QToF-MS/MS metabolic profiling of CSPE led to the identification of twenty-nine metabolites. CSPE …

Compliance With A Nurse-Driven Hypoglycemia Protocol: Time From Hypoglycemia Event To Euglycemia, Robin A. Chappell

Student Scholarly Projects

Practice Problem: Hypoglycemia is a known complication of diabetes mellitus and is considered one of the top three adverse drug events by the U.S. Department of Health and Human Services (2019) because it is common, clinically significant, measurable, and preventable.

PICOT: The PICOT question that guided this project was: In non-critical hospitalized adult patients on medical-surgical units with documented HGEs, how does active surveillance for strict adherence to a nurse-driven hypoglycemia protocol, compared to no surveillance, affect the time from hypoglycemia to euglycemia?

Evidence: Treatment of hypoglycemia is commonly inconsistent and prolonged; however, active surveillance and monitoring of a …

Acute Asthma Exacerbation Treatment And Impact In A Pediatric Emergency Department, Sarah Jindoyan, Paige Barber

College of Science and Health Theses and Dissertations

Pediatric asthma exacerbation account for more than 1.8 million Emergency Department visits annually and has been labeled as a global epidemic as the prevalence, morbidity and mortality have significantly increased over the past forty years (Dexheimer et al., 2013). While asthma is recognized as the most common chronic disease in children, issues of under-diagnosis and undertreatment persist (Serebrisky & Wiznia, 2019). Because of the severity of this issue, it is important to further examine the current process in place and what steps can be taken to improve this process.

Acquired knowledge on the research topic is based on objective findings …

There's An App For That: Promoting Health App Use In Rural Ireland, Noor Yahya, Marcus Simon

Undergraduate Research Symposium

Problem Statement: Smartphones and mobile applications (commonly referred to as apps) were first introduced in the late 20th century and early 21st century. Due to the public’s time constraints, lack of transportation, lack of medical insurance, and a growing desire for healthier lifestyles, the total global mHealth market forecast to reach 100 billion dollars in 2021 – a fivefold increase from 21 billion in 2016. mHealth apps have been successfully used for health promotion activities but barriers such as lack of knowledge and comfort in using health apps exist.

Purpose: Evaluate readiness of a rural community and the …

“It’S Pretty Hard To Make Friends Over A Zoom Meeting Room”: Understanding The Recreational Experiences Of Youth With Type 1 Diabetes During Covid-19, Ryan Malpaya, Rowan Williams

Undergraduate Research Symposium

Youth with diabetes frequently have limited access to traditional camps because of the need for accessible medical staff (Hill, E., 2019). COVID-19 has made it even more difficult for youth with type 1 diabetes to participate in any youth development programs due to the pandemic restrictions. During the pandemic, it is unknown if youth with T1D are able to engage in any recreational activities that may teach them resilience and independence in managing their medical condition. The purpose of this study was to see how youth with T1D cope in an altered recreation environment as a result of COVID-19

Using …

Undergraduate Session Ii: Presentation 2 - Quality Versus Quantity Of Life: Breast Cancer Treatments And Survival Rates, Casey Almond

Life of the Scholar Multidisciplinary Conference

This study; Quality Versus Quantity of Life: Treatments for Breast Cancer and Survival Rates, focuses on helping patients who receive a diagnosis of breast cancer decide how they would like to proceed in treatment. In many stage three and four cases of breast cancer, patients are presented with various treatment options. Some patients may consider the poor quality of life that could result from initiating treatment, others will be contingent on accepting all treatments to prolong their length of life, and others may choose to receive no treatment at all. This research may serve as a guide to empower patients …

2021-03-20_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …

2021-03-20_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

2021-03-20_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled. It is updated Monday - Saturday.
This report is provisional and subject to change. City of Detroit and Wayne County are reported separately. MDHHS began tracking probable cases April 5, 2020. FCI indicates federal correctional institute. MDOC indicates Michigan Department of Corrections. Diagnostic tests, including nucleic acid amplification/real-time polymerase chain reaction (NAAT/RT-PCR) and rapid virus antigen detection point of …

Examining The Impact Of Socioeconomic Variables On Covid-19 Death Rates At The State Level, James L. Doti

Economics Faculty Articles and Research

This study uses a step-wise regression model to identify the socioeconomic variables most significant in explaining COVID-19 death rates on a state-level basis. The regression tests cover the 1/1/2020 to 12/1/2020 period as well as the first and second halves of 2020. This study also uses the Oxford stringency index to measure more precisely the efficacy of governmental mandates at the state level. The results in this study rigorously showed that while the density variables were the most significant explanatory variables during the first half of the year, their significance fell during the second half. Use of the Oxford stringency …

Multi-Level Considerations For Optimal Implementation Of Long-Acting Injectable Antiretroviral Therapy To Treat People Living With Hiv: Perspectives Of Health Care Providers Participating In Phase 3 Trials, Andrea Mantsios, Miranda Murray, Tahilin S. Karver, Wendy Davis, Noya Galai, Princy Kumar, Susan Swindells, U. Fritz Bredeek, Rafael Rubio García, Antonio Antela, Santiago Cenoz Gomis, Miguel Pascual Bernáldez, Maggie Czarnogorski, Krischan Hudson, Nicki Walters, Deanna Kerrigan

Journal Articles: Infectious Diseases

BACKGROUND: Long-acting injectable antiretroviral therapy (LA ART) has been shown to be non-inferior to daily oral ART, with high patient satisfaction and preference to oral standard of care in research to date, and has recently been approved for use in the United States and Europe. This study examined the perspectives of health care providers participating in LA ART clinical trials on potential barriers and solutions to LA ART roll-out into real world settings.

METHODS: This analysis draws on two data sources: (1) open-ended questions embedded in a structured online survey of 329 health care providers participating in the ATLAS-2 M …

A Rare Case Of A Plurihormonal Pituitary Adenoma, Alisha Hossain Do, Lindor Gelin Do, Arjan Ahluwalia Md, Emily C. Skutnik Do, Sonum Singh Md, Gretchen A. Perilli Md, Sharmila C. Koshy Md

Department of Medicine

No abstract provided.

The Difficulty Of Post-Operative Surveillance Of Calcitonin Negative Medullary Thyroid Cancer, Emily C. Skutnik Do, Rachel Kinney Do, Rebecca A. Lopes Do, Chun Siu Do, Angela Magdaleno Do, Gretchen A. Perilli Md

Department of Medicine

No abstract provided.

A Principal Components Analysis Of Factors Associated With Successful Implementation Of An Lvad Decision Support Tool, Kristin M Kostick, Meredith Trejo, Arvind Bhimaraj, Andrew Civitello, Jonathan Grinstein, Douglas Horstmanshof, Ulrich P Jorde, Matthias Loebe, Mandeep R Mehra, Nasir Z Sulemanjee, Vinay Thohan, Barry H Trachtenberg, Nir Uriel, Robert J Volk, Jerry D Estep, J S Blumenthal-Barby

Faculty, Staff and Students Publications

BACKGROUND: A central goal among researchers and policy makers seeking to implement clinical interventions is to identify key facilitators and barriers that contribute to implementation success. Despite calls from a number of scholars, empirical insights into the complex structural and cultural predictors of why decision aids (DAs) become routinely embedded in health care settings remains limited and highly variable across implementation contexts.

METHODS: We examined associations between "reach", a widely used indicator (from the RE-AIM model) of implementation success, and multi-level site characteristics of nine LVAD clinics engaged over 18 months in implementation and dissemination of a decision aid for …

Shared Developmental Gait Disruptions Across Two Mouse Models Of Neurodevelopmental Disorders, Rachel M Rahn, Claire T Weichselbaum, David H Gutmann, Joseph D Dougherty, Susan E Maloney

2020-Current year OA Pubs

BACKGROUND: Motor deficits such as abnormal gait are an underappreciated yet characteristic phenotype of many neurodevelopmental disorders (NDDs), including Williams Syndrome (WS) and Neurofibromatosis Type 1 (NF1). Compared to cognitive phenotypes, gait phenotypes are readily and comparably assessed in both humans and model organisms and are controlled by well-defined CNS circuits. Discovery of a common gait phenotype between NDDs might suggest shared cellular and molecular deficits and highlight simple outcome variables to potentially quantify longitudinal treatment efficacy in NDDs.

METHODS: We characterized gait using the DigiGait assay in two different murine NDD models: the complete deletion (CD) mouse, which models …

Dynamics Of Endurance Indicators In Young Middle-Distance Runners, Dilnoza Rakhmatova

Eurasian Journal of Sport Science

Aim: Teaching 10 ages children to run medium distances, improving general physical fitness, improving the body in all aspects, and mastering running exercise techniques while increasing the level of special physical fitness.

Methods and Results: The results of the 10 ages children running 600 meters in the first year of the primary training group were 2: 06.0 ± 0.21 in the experimental group and 2: 08.0 ± 0.30 in the control group. The statistical difference between them did not differ on the Student- t criterion t = 0.44.

Conclusion: The results of the research showed that high-level performance did not …

Implementation Of An Opioid Risk Assessment Tool In An Acute Pain Service, Emoshoke Owie

Graduate Research Showcase

The U.S is currently experiencing an opioid epidemic because of the number of people that died from an opioid overdose. An estimated 10 million people aged 12 or older misused opioids in 2019. Studies have shown that applying a systematic method for risk stratification for all patients considered for opioid therapy could be vital to screening patients at risk for opioid misuse to ease the opioid epidemic. Based on the assumption that the Diagnosis Intractability Reliability Efficacy (DIRE), an opioid risk assessment tool, would substantially change the providers’ prescribing decisions, it was implemented in an Acute Pain Service. Purposive sampling …

Medical School Watercooler Newsletter - March 19, 2021, Lindsey Lyle

Watercooler Newsletter

This is the March 19, 2021 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents Include:

• Medical students are back in person for Match Day 2021
• Med School Café video online: 'Breast Cancer'
• Mark your calendar for upcoming grand rounds
• Medical students match in military residency programs

Overcoming Communication Barriers: An Evaluation Of Communication Devices For Healthcare Providers Wearing Powered Air-Purifying Respirators (Paprs), Trevor Hebenstreit, Geoffrey Ho, Amy Tronnier, Everett Chu, Ivy Benjenk, Paul Dangerfield, Ryan Keneally, Timothy Liu, Marian Sherman

Anesthesiology and Critical Care Medicine Faculty Posters and Presentations

No abstract provided.

2021-03-19_Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

The webpage was obtained from Michigan's Coronavirus Cumulative Data page, under the link Hospitals. Data is self-reported by hospitals daily to the EM Resource System per MDHHS Director Robert Gordon's Emergency Order.

Contains the tables Statewide Hospital Capacity Report for COVID-19, COVID-19 Metrics, Statewide Hospital Available PPE Tracking for COVID-19, as well as the tables PPE Days On Hand and Patient Census.

2021-03-19_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

2021-03-19_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …

Coronavirus Update 3-19-2021, The Coronavirus Planning Team

University Briefings & Virtual Events

Student Vaccination Poll --Weekend Fun --Enjoy the Event Tent in the Chapel Quad.

Cerebellar Kv3.3 Potassium Channels Activate Tank-Binding Kinase 1 To Regulate Trafficking Of The Cell Survival Protein Hax-1., Yalan Zhang, Luis Varela, Klara Szigeti-Buck, Adam Williams, Milan Stoiljkovic, Matija Šestan-Peša, Jorge Henao-Mejia, Pasquale D'Acunzo, Efrat Levy, Richard A Flavell, Tamas L Horvath, Leonard K Kaczmarek

Faculty Research 2021

Mutations in KCNC3, which encodes the Kv3.3 potassium channel, cause degeneration of the cerebellum, but exactly how the activity of an ion channel is linked to the survival of cerebellar neurons is not understood. Here, we report that Kv3.3 channels bind and stimulate Tank Binding Kinase 1 (TBK1), an enzyme that controls trafficking of membrane proteins into multivesicular bodies, and that this stimulation is greatly increased by a disease-causing Kv3.3 mutation. TBK1 activity is required for the binding of Kv3.3 to its auxiliary subunit Hax-1, which prevents channel inactivation with depolarization. Hax-1 is also an anti-apoptotic protein required for survival …

Evaluating The Use Of An Interdependent Group Contingency In Online Graduate Courses To Increase Engagement, Tiana Evans

USF Tampa Graduate Theses and Dissertations

Enrollment in online academic programs has increased substantially in recent years (Allen & Seaman, 2011) and is especially relevant due to the COVID-19 pandemic (Khalil et al., 2020). Peer interaction and engagement opportunities are strategies associated with course satisfaction, test performance, and grades and should be incorporated into online courses (Conaway et al. 2005). Group contingencies have been commonly studied in face-to-face classrooms and have been found to be effective intervention in changing target behavior in elementary and secondary education settings (Barrish et al., 1969; Deshais et al., 2019; Harris & Sherman, 1973; Mitchell et al. 2015; Wiskow et al., …

2021-03-19_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled. It is updated Monday - Saturday.
This report is provisional and subject to change. City of Detroit and Wayne County are reported separately. MDHHS began tracking probable cases April 5, 2020. FCI indicates federal correctional institute. MDOC indicates Michigan Department of Corrections. Diagnostic tests, including nucleic acid amplification/real-time polymerase chain reaction (NAAT/RT-PCR) and rapid virus antigen detection point of …

Mothers Without Borders Program Evaluation: Establishing Effective Program Evaluation To Assess Holistic Orphan Care Initiatives In Zambia, Alyssa Baer

Undergraduate Honors Theses

This paper uses an interdisciplinary approach—combining theories and methodologies from the Social Impact and Public Health disciplines—to design an evaluation of Mothers Without Borders’ (MWB) programs in Lusaka, Zambia. Their programs aim to support communities as they care for children in crisis living in their communities—with a focus on communities with large populations of orphaned and vulnerable children (OVC) as a result of the HIV/AIDS epidemic. This paper provides an overview of the orphan crisis, international orphan care standards, and evaluation practices in order to understand and design an effective evaluation plan for the organization. This project aims to provide …

Rna-Based Therapies: A Cog In The Wheel Of Lung Cancer Defense, Parvez Khan, Jawed A. Siddiqui, Imayavaramban Lakshmanan, Apar Kishor Ganti, Ravi Salgia, Maneesh Jain, Surinder K. Batra, Mohd W. Nasser

Journal Articles: Biochemistry & Molecular Biology

Lung cancer (LC) is a heterogeneous disease consisting mainly of two subtypes, non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC), and remains the leading cause of death worldwide. Despite recent advances in therapies, the overall 5-year survival rate of LC remains less than 20%. The efficacy of current therapeutic approaches is compromised by inherent or acquired drug-resistance and severe off-target effects. Therefore, the identification and development of innovative and effective therapeutic approaches are critically desired for LC. The development of RNA-mediated gene inhibition technologies was a turning point in the field of RNA biology. The critical regulatory …

Correction To Some Statements About Aluminum In Sulaiman Et Al., Robert A. Yokel

Pharmaceutical Sciences Faculty Publications

No abstract provided.