Medicine and Health Sciences Commons^™

I Matter: Understanding The Self-Care Practices Of School Counselors During The Covid-19 Pandemic And How Internal And External Factors Create Barriers, Alisha Rene Marie Jones

Graduate Theses and Dissertations

Diminished self-care practices and heightened stress of school counselors is a continuing problem in education. With role ambiguity, high student-to-counselor ratios, emotional exhaustion, and others adding pressure to the roles and responsibilities of school counselors, this study investigated the self-care practices of Missouri school counselors and the internal and external factors which influence them, specifically within the context COVID-19. Clayton Alderfer’s (1972) Existence, Relatedness, and Growth theory was used as a theoretical framework for chosen self-care practices represented in this study and was supported by Robert Kegan’s and Lisa Lahey’s (2009) Immunity to Change theory to understand the competing commitments …

A Descriptive Case Study Of The Challenges Of Drug And Alcohol Counselors, Ruben Herron

Graduate Theses and Dissertations

Substance abuse is the number one public health problem in Oklahoma and nationally. Annual related expenses of substance abuse in Oklahoma are nearly $2 billion. This qualitative descriptive case study asks the question what are the challenges of substance-abuse counseling? The researcher will be describing in detail the history of drug and alcohol treatment and counseling in America. Using interviews, observations and document collection which will allow the interviews voices to be heard.

Distress Tolerance As A Potential Target For Change: The Relationship Between Distress Tolerance, Craving, And Alcohol Consumption In A Lab-Based Experiment, Isabel F. Augur

Graduate Theses and Dissertations

Distress tolerance (DT) has recently been studied as a potential catalyst for the development ofalcohol use disorder (AUD). Research exploring the relationship between DT and craving is limited and has primarily focused on nicotine craving. Furthermore, there are no current studies examining the relationship between DT and alcohol consumption. This study was designed to fill this gap in the literature, which may shed light on a potentially important target for alcohol use treatment. Additionally, the role of mindfulness was explored in the context of the relationship between DT and alcohol craving and consumption, with the intention of expanding on the …

Laughter As A Priming Agent For Change, Linnea M. Heintz

Graduate Theses and Dissertations

The purpose of this study was to analyze the importance of laughter as a factor in influencing employee job satisfaction ratings. The Job Satisfaction Survey (Spector, 1985, 1997) and pulses of laughter were used in this study. To explore the relationship between laughter and job satisfaction, results of the Job Satisfaction Survey (Spector, 1994) were collected quarterly (four times a year) for three consecutive years, beginning six months prior to the start of the two-year study and six months post. The study sample was composed of 545 employees (34% male, 66% female) operating out of 10 employee-owned retail chain locations …

Research Productivity Of India And Iran In Stomach Cancer: A Bibliometric Study, Rabiya Mushtaq, Fayaz Ahmad Loan

Library Philosophy and Practice (e-journal)

The study aims to provide an insight into the global research productivity in stomach cancer with an in-depth analysis of the growth & development of India and Iran. The study focuses on the authorship collaborative patterns among Indian and Iranian medical scientists as well. The study was conceived with the selection of terms on “Stomach cancer”. The terms- “Stomach Cancer, Stomach Neoplasm, Gastric Cancer, and Gastric Neoplasm” were selected from the Medical Subject Headings (MeSH) to retrieve the data from the Web of Science (WoS). The Boolean Operator “OR” was executed to retrieve the records. The data was retrieved …

Immigrant Families' Health-Related Information Behavior On Instant Messaging Platforms: Health-Related Information Exchange In Immigrant Family Groups On Instant Messaging Platforms, Lev Poretski, Taamannae Taabassum, Anthony Tang

Research Collection School Of Computing and Information Systems

For immigrant families, instant messaging family groups are a common platform for sharing and discussing health-related information. Immigrants often maintain contact with their family abroad and trust information in shared IM family groups more than the information from local authorities and sources. In this study, we aimed to understand health-related information behaviors of immigrant families in their IM family groups. Based on the interviews with 6 participants from immigrant families to Canada, we found that immigrant families’ discourse on IM platforms is motivated by love and care for other family members. The families used local and international sources of information, …

Oidpr: Optimized Insulin Dosage Via Privacy‐Preserving Reinforcement Learning, Zuobin Ying, Yun Zhang, Shuanglong Cao, Shengmin Xu, Maode Ma

Research Collection School Of Computing and Information Systems

The precision of insulin dosage is essential in the process of diabetes treatment. The fact is providing precise dosage is almost impossible for clinicians since blood sugar levels are dynamically affected by many factors. Even though some auxiliary dosing systems have been proposed, the required real‐time physical data about the health situation of diabetics is still hard to synchronize to the end‐devices instantly. The traditional personalized drug delivery frameworks for accurate dosing of insulin always collect and transmit medical data in cleartext, which raises privacy problems. In this article, we propose a framework for an optimized insulin dosage via privacy‐preserving …

A Novel Mra-Based Framework For Segmenting The Cerebrovascular System And Correlating Cerebral Vascular Changes To Mean Arterial Pressure, Fatma Taher, Heba Kandil, Yitzhak Gebru, Ali Mahmoud, Ahmed Shalaby, Shady El‐Mashad, Ayman El‐Baz

All Works

Blood pressure (BP) changes with age are widespread, and systemic high blood pressure (HBP) is a serious factor in developing strokes and cognitive impairment. A non‐invasive methodology to detect changes in human brain’s vasculature using Magnetic Resonance Angiography (MRA) data and correlation of cerebrovascular changes to mean arterial pressure (MAP) is pre-sented. MRA data and systemic blood pressure measurements were gathered from patients (n = 15, M = 8, F = 7, Age = 49.2 ± 7.3 years) over 700 days (an initial visit and then a follow‐up period of 2 years with a final visit.). A novel segmentation algorithm …

Potassium For Two: Management Of Refractory Electrolyte Disturbances In Gitelman Syndrome During Pregnancy, Eric Torkildsen Md, Yesha K. Shah Do, Sharon E. Maynard Md

Department of Medicine

No abstract provided.

The Role Of Music In The Trauma Narrative And “Storytelling”: Perspectives Of Clinicians, Taylorlyn N. Mehnert

Masters Theses

There is a lack of detailed literature describing how music is used for expressing and processing the trauma narrative. This study used a constructivist grounded theory approach through an anti-oppressive lens to explore the ways in which music therapists use music in exploring clients’ stories. The term “story” is used as opposed to “narrative” or “memory” to incorporate a broader definition of expression including non-verbal, musical, metaphorical, or any other method the client chooses. Eight board-certified music therapists (MT-BC) were interviewed regarding their use of music in the context of clients’ stories. Braun and Clarke’s reflexive thematic analysis was used …

Electroencephalography Resting-State Networks In People With Stroke, Dylan B. Snyder, Brian D. Schmit, Allison S. Hyngstrom, Scott A. Beardsley

Biomedical Engineering Faculty Research and Publications

Introduction

The purpose of this study was to characterize resting-state cortical networks in chronic stroke survivors using electroencephalography (EEG).

Methods

Electroencephalography data were collected from 14 chronic stroke and 11 neurologically intact participants while they were in a relaxed, resting state. EEG power was normalized to reduce bias and used as an indicator of network activity. Correlations of orthogonalized EEG activity were used as a measure of functional connectivity between cortical regions.

Results

We found reduced cortical activity and connectivity in the alpha (p < .05; p = .05) and beta (p < .05; p = .03) bands after stroke while connectivity …

Ancestry Specific Associations Of A Genetic Risk Score, Dietary Patterns And Metabolic Syndrome: A Longitudinal Aric Study, Dale S Hardy, Susan B Racette, Jane T Garvin, Hirut T Gebrekristos, Tesfaye B Mersha

2020-Current year OA Pubs

BACKGROUND: Associations have been observed among genetic variants, dietary patterns, and metabolic syndrome (MetS). A gap in knowledge is whether a genetic risk score (GRS) and dietary patterns interact to increase MetS risk among African Americans. We investigated whether MetS risk was influenced by interaction between a GRS and dietary patterns among Whites and African Americans. A secondary aim examined if molecular genetic clusterings differed by racial ancestry.

METHODS: We used longitudinal data over 4-visits (1987-1998) that included 10,681 participants aged 45-64y at baseline from the Atherosclerosis Risk in Communities study (8451 Whites and 2230 African Americans). We constructed a …

The Impact Of Covid-19 On The Well-Being And Cognition Of Older Adults Living In The United States And Latin America, Ganesh M Babulal, Ana Baena, Jorge Llibre-Guerra, Et Al

2020-Current year OA Pubs

BACKGROUND: In the COVID-19 pandemic, older adults from vulnerable ethnoracial groups are at high risk of infection, hospitalization, and death. We aimed to explore the pandemic's impact on the well-being and cognition of older adults living in the United States (US), Argentina, Chile, Mexico, and Peru.

METHODS: 1,608 (646 White, 852 Latino, 77 Black, 33 Asian; 72% female) individuals from the US and four Latin American countries aged ≥ 55 years completed an online survey regarding well-being and cognition during the pandemic between May and September 2020. Outcome variables (pandemic impact, discrimination, loneliness, purpose of life, subjective cognitive concerns) were …

Acetyl-Coa And Metabolite Fluxes Regulate White Adipose Tissue Expansion, Jessica B Felix, Aaron R Cox, Sean M Hartig

Faculty, Staff and Students Publications

White adipose tissue (WAT) depends on coordinated regulation of transcriptional and metabolic pathways to respond to whole-body energy demands. We highlight metabolites that contribute to biosynthetic reactions for WAT expansion. Recent studies have precisely defined how byproducts of carbohydrate and lipid metabolism affect physiological and endocrine functions in adipocytes. We emphasize the critical emerging roles of short-chain fatty acids (SCFAs) and tricarboxylic acid (TCA) cycle metabolites that connect lipogenesis to WAT energy balance and endocrine functions. These insights address how adipocytes use small molecules generated from central carbon metabolism to measure responses to nutritional stress.

Frequency-Modulated Multiple-Tone Distortion Product Otoacoustic Emissions In Young Children With Normal Hearing, Kathryn Arielle Vlietstra Baker

Graduate Theses/Dissertations

Distortion-product otoacoustic emissions (DPOAEs) are objective tests of the integrity of the outer hair cells of the cochlea in response to a single-tone pair stimulus. Despite advances in DPOAEs test protocols and technology, there is little research about the use of frequency modulated tones to improve response characteristics. This study evaluates the efficacy of a new frequency modulated stimulus with multiple-tone pair DPOAEs (mDPOAEs) compared to the standard stimulus protocol for mDPOAEs to determine whether frequency modulation (FM) will achieve more robust and faster results. Normative data for this novel test protocol were obtained in 11 healthy normal-hearing children aged …

Presence And Characteristics Of Axial Skeleton Fractures Experienced By Cheerleaders And Gymnasts From 2010-2019, Jordan Trimm

Honors Theses

Context: Cheerleading and gymnastics are sports containing dangerous skills that place athletes at risk of severe injuries, such as axial skeleton fractures. In addition, cheerleaders and gymnasts frequently have less access to on-site healthcare, such as athletic training services, which requires increased utilization of emergency departments. Objective: To compare national estimates of axial skeleton fractures in cheerleading and gymnastics by injury characteristics over a 10-year period. Design: Descriptive Epidemiological. Setting: United States Emergency Department via the National Electronic Injury Surveillance System Database. Participants: Cheerleaders and gymnasts presenting to a sample of US hospitals. Interventions: Independent variables included body region fractured. …

Undergraduate Nursing Students’ Knowledge Of Endometriosis: A Pilot Study, Stephanie Schlorke

Honors Theses

This descriptive post-test design study was conducted to assess knowledge level of undergraduate nursing students regarding risk factors, clinical manifestations, age of diagnosis, common psychiatric co-morbidities, treatment methods, and pathophysiology of endometriosis. An author-created 8 question multichoice and select all that apply questionnaire was used to collect the data. Twenty-eight students responded to the questionnaire. The results were divided to compare knowledge differences between second-semester and fifth-semester students.

It was determined that the undergraduate nursing students have a working knowledge of endometriosis, but there are knowledge gaps that need to be addressed. Fifth-semester participants scored higher than the second-semester participants …

The Poly(Adp-Ribosyl)Ation Of Brd4 Mediated By Parp1 Promoted Pathological Cardiac Hypertrophy, Zhenzhen Li, Zhen Guo, Rui Lan, Sidong Cai, Zhirong Lin, Jingyan Li, Junjian Wang, Zhuoming Li, Peiqing Liu

2020-Current year OA Pubs

The bromodomain and extraterminal (BET) family member BRD4 is pivotal in the pathogenesis of cardiac hypertrophy. BRD4 induces hypertrophic gene expression by binding to the acetylated chromatin, facilitating the phosphorylation of RNA polymerases II (Pol II) and leading to transcription elongation. The present study identified a novel post-translational modification of BRD4: poly(ADP-ribosyl)ation (PARylation), that was mediated by poly(ADP-ribose)polymerase-1 (PARP1) in cardiac hypertrophy. BRD4 silencing or BET inhibitors JQ1 and MS417 prevented cardiac hypertrophic responses induced by isoproterenol (ISO), whereas overexpression of BRD4 promoted cardiac hypertrophy, confirming the critical role of BRD4 in pathological cardiac hypertrophy. PARP1 was activated in ISO-induced …

Content Validity Of Aba Language Assessments In The Totality Of Skinner's Verbal Operant Theory, Taylor Marie Lauer

Graduate Theses/Dissertations

Content validity describes the degree of which a measure represents all the components of the overall construct being measured. Behavior analytic language assessments are largely based on Skinner’s verbal operant theory (1957). Three behavior analytic language assessments were utilized to measure the coverage of Skinner’s verbal behavior theory: the VB-MAPP, ABLLS-R, and PEAK. The purpose of the current study was to examine the content validity of each of these assessments coverage on the totality of Skinner’s verbal operant theory. Expressive items on each of the three assessments were compared to definitions of Skinner’s verbal operants and were coded as the …

Sodium Pyruvate Ameliorates Influenza A Virus Infection In Vitro And In Vivo, Jessica M. Reel

Graduate Theses/Dissertations

Pyruvate is produced in duplicate at the end of glycolysis in addition to ATP and NADH. Pyruvate is the metabolite of choice in most cells, whether obtained exogenously or endogenously. Recently we found that the addition of pyruvate’s conjugate base, sodium pyruvate, to cell culture media dampened the immune response to influenza A virus (IAV) infection in cultured innate immune cells. Thus, I decided to investigate the mechanism and potential for treatment of IAV. In vitro using bone marrow derived macrophages that were infected with IAV we found that adding sodium pyruvate to the media decreased immune signaling pathways through …

Healthcare Workers' And Students' Current Knowledge And Perceptions Of Medical Marijuana Laws, Cole Isaac Stomp

Graduate Theses/Dissertations

As states across the United States enact Medical Marijuana Laws (MMLs), it is important to understand the implications of these policies and what effect they may have on the current healthcare industry. There is a lack of medical marijuana (MM) access due to novel policy and discrepancy of state legislature between those legalizing MM use versus current federal law. As of November, 2018, the state of Missouri has adopted MM policy, yet the perceptions, attitudes, and knowledge of MM and MMLs for current and future healthcare workers remains unknown. Therefore, the purpose of this study was to survey local healthcare …

Identifying And Comparing Transcriptome Alterations In Saccharomyces Cerevisiae Exposed To A Variety Of Quantum Dots, Cullen Horstmann

Graduate Theses/Dissertations

The primary focus of my research was to obtain global gene expression profiles of baker’s yeast exposed to sub-lethal doses of nanoparticles, such as silver nanoparticles (AgNPs), yellow- emitting CdSe/ZnS quantum dots (QDs), green-emitting CdSe/ZnS QDs, and InP/ZnS QDs, to reveal novel insights on their unique mechanisms of toxicity. Despite their diverse applications, their long-lasting effects on the environment and human health are not well understood. To assess their toxicity, I administered experiments that exposed Saccharomyces cerevisiae to a variety of nanoparticles and measured cell viability, ROS levels, and changes in gene expression. Most notably, I used RNA-sequencing (RNA-seq) to …

Spirulina Platensis Inclusion Reverses Circulating Pro-Inflammatory (Chemo)Cytokine Profiles In Broilers Fed Low-Protein Diets, Garrett J. Mullenix, Elizabeth S. Greene, Nima K. Emami, Guillermo Tellez-Isaias, Walter G. Bottje, Gisela F. Erf, Michael T. Kidd Jr., Sami Dridi

Poultry Science Faculty Publications and Presentations

Proteins are considered the most expensive nutrients in commercial modern broiler production, and their dietary inclusion at low levels is pivotal to minimize feed costs and reduce nitrogen waste. The quest for an environmentally friendly source of proteins that favor the formulation of low protein diets without compromising broiler health, welfare, and growth performance has become a hotspot in nutrition research. Due to its high protein content, the naturally growing Spirulina microalgae is considered a promising nutrient source. The purpose of the present study was, therefore, to determine the effects of Spirulina supplementation on liver bacterial translocation, hematological profile, and …

Population Genomics Of Invasive Rodents On Islands: Genetic Consequences Of Colonization And Prospects For Localized Synthetic Gene Drive, Kevin P. Oh, Aaron B. Shiels, Laura Shiels, Dimitri V. Blondel, Karl J. Campbell, J. Royden Saah, Alun L. Lloyd, Paul Q. Thomas, Fred Gould, Zaid Abdo, John R. Godwin, Antoinette J. Piaggio

United States Department of Agriculture Wildlife Services: Staff Publications

Introduced rodent populations pose significant threats worldwide, with particularly severe impacts on islands. Advancements in genome editing have motivated interest in synthetic gene drives that could potentially provide efficient and localized suppression of invasive rodent populations. Application of such technologies will require rigorous population genomic surveys to evaluate population connectivity, taxonomic identification, and to inform design of gene drive localization mechanisms. One proposed approach leverages the predicted shifts in genetic variation that accompany island colonization, wherein founder effects, genetic drift, and island-specific selection are expected to result in locally fixed alleles (LFA) that are variable in neighboring nontarget populations. Engineering …

Exploring Online Mental Health Services: A Qualitative Study For First-Year College Students, Leandrian J. Wright

Electronic Theses and Dissertations

American first-year college students are faced with mental health issues, such as anxiety and depression, which can have a negative impact on their academic performance. Research shows that students who suffer from mental illness, such as anxiety and depression, fear their condition will be perceived negatively by their peers and professors. The literature also suggests that U.S. colleges and universities can be more proactive in offering students resources for their mental health concerns to decrease anxiety and depression. It appears that absent or limited mental health resources have failed to address rising cases of student mental illness, and more specifically, …

Impact Of Leader Rounds On Perceptions Of The Culture Of Safety, Heather D. Ray

Electronic Theses and Dissertations

A culture of safety in healthcare settings supports a caring environment and practices that produce quality patient outcomes. Leadership is instrumental in creating a culture of safety. The purpose of this quantitative pretest-posttest design project was to determine if the implementation of leader rounds in an acute care hospital had an impact on staff nurses’ perceptions of safety culture as measured by the Safety Attitudes Questionnaire. The setting was a midsize acute care hospital with a target population of dayshift nurses working in the telemetry service line. Leader rounds were conducted over a six-week timeline by the department director. Data …

Gardnerella Vaginalis Promotes Group B Streptococcus Vaginal Colonization, Enabling Ascending Uteroplacental Infection In Pregnant Mice, Nicole M Gilbert, Lynne R Foster, Bin Cao, Yin Yin, Indira U Mysorekar, Amanda L Lewis

2020-Current year OA Pubs

BACKGROUND: Group B Streptococcus is a common vaginal bacterium and the leading cause of invasive fetoplacental infections. Group B Streptococcus in the vagina can invade through the cervix to cause ascending uteroplacental infections or can be transmitted to the neonate during vaginal delivery. Some studies have found that women with a "dysbiotic" polymicrobial or Lactobacillus-depleted vaginal microbiota are more likely to harbor group B Streptococcus. Gardnerella vaginalis is often the most abundant bacteria in the vaginas of women with dysbiosis, while being detected at lower levels in most other women, and has been linked with several adverse pregnancy outcomes. Mouse …

The Effect Of Convalescent Plasma Therapy On Mortality Among Patients With Covid-19: Systematic Review And Meta-Analysis, Stephen A Klassen, Brenda J Grossman, Jeffrey P Henderson, Et Al

2020-Current year OA Pubs

To determine the effect of COVID-19 convalescent plasma on mortality, we aggregated patient outcome data from 10 randomized clinical trials, 20 matched control studies, 2 dose-response studies, and 96 case reports or case series. Studies published between January 1, 2020, and January 16, 2021, were identified through a systematic search of online PubMed and MEDLINE databases. Random effects analyses of randomized clinical trials and matched control data demonstrated that patients with COVID-19 transfused with convalescent plasma exhibited a lower mortality rate compared with patients receiving standard treatments. Additional analyses showed that early transfusion (within 3 days of hospital admission) of …

Impact Of Acne On Quality Of Life In Young Pakistani Adults And Its Relationship With Severity: A Multicenter Study, Shaheen Naveed, Sadia Masood, Atiya Rahman, Safia Awan, Saadia Tabassum

Department of Medicine

Objectives: The current study aimed to determine the effect of acne vulgaris on quality of life of young adults and to assess the correlation between acne severity and impairment of quality of life (QOLI).
Methods: In this multi-center cross-sectional study, 163 young adults with acne vulgaris were assessed for severity and quality of life impairment between December 2016 and May 2017 at three tertiary care hospitals. Cardiff Acne Disability Index (CADI) was used to assess the quality of life while the severity of acne measured by Global Acne Grading System (GAGS). Data were collected on standardized forms, with CADI, GAGS …

Key Performance Indicators Of Health Cte Students At For-Profit Colleges And Public Community Colleges, Souraya Hajjar

Open Access Theses & Dissertations

The advent of for-profit colleges to the higher education scene in the U.S. has challenged public community colleges on all levels; financial, academic, and consumerism. Research has shown that key performance indicators are more favorable at public community colleges than at for-profit colleges. Determining size and type of colleges, ethnicity and gender differences that contribute to total graduation rate of health Career and Technical Education (CTE) students will add to the limited research on the relationship between these constructs and provide information to prospective health CTE students about college enrollment. The study aims to examine institutional performance variables to assist …