Medicine and Health Sciences Commons^™

The Acute Effects Of Different Squat Intensities On Vertical Jump Performance, Andrew R. Hill, Daniel L. Laudermilk, Soon-Mi Choi

International Journal of Exercise Science: Conference Proceedings

Post activation potentiation (PAP) is defined as a short-term improvement in performance as a result of using a resistance exercise. The phenomenon of PAP has been shown to acutely increase athletic performance with back squats as an effective modality. PURPOSE: This study investigated acute effects of different back squat intensities on the countermovement vertical jump (CMJ). METHODS: Participants were 13 to 18-yr-old healthy male (n=8) and female (n=3) who participated in regular resistance training for at least 6 months and have played in a University Interscholastic League (UIL) within the past 6 months. One Repetition Maximum (1-RM) was measured within …

Effects Of Caffeine Dose Timing On The Time-Course Of Diuresis During Sodium-Aided Hyperhydration, Phillip D. Wickenheiser, Shelby Greene, Elizaveta Roslanova, Dave Morris

International Journal of Exercise Science: Conference Proceedings

When used alone, both caffeine and sodium-aided hyperhydration (SAH) can be ergogenic. Caffeine, when used with SAH, promotes diuresis, but hyperhydration can be achieved, albeit at lower levels than with SAH alone. In previous caffeine and SAH work, caffeine induced diuresis occurred only within 15 min of consumption of a bolus of caffeine, NaCl, and H₂O. This suggests that caffeine-induced diuresis may occur for only 15 min after its consumption, and/or that the diuretic effect of caffeine is dependent on hydration levels. Caffeine has been shown to be ergogenic when taken as little as 5 min before exercise; …

Comparison Of Acute Cardiometabolic Responses In A 7-Minute Body Weight Circuit To A 7-Minute Hiit Cycle Protocol, Cruz Armas, Robert J. Kowalsky Jr, Christopher M. Hearon

International Journal of Exercise Science: Conference Proceedings

Many smartphone applications available promote exercise engagement, specifically in short bouts of time. One such application “The 7-minute workout challenge” promotes a brief exercise bout, however details on the potential cardiometabolic health benefit is lacking. Purpose:To investigate the acute cardiometabolic responses of a 7-minute body-weight resistance exercise circuit (HICE) compared to a 7-minute high intensity interval training cycle protocol (HIIE). Methods: Apparently healthy and active young adults (N=12, 50% Female, 24.0±3.4 yr, BMI: 28.1±6.4 kg/m²) were enrolled in a randomized crossover study (HICE vs HIIE). The 12 HICE exercises were 30 seconds each using a standardized cadence, …

Investigating The Use Of Vibration Platform And Blood Flow Restriction As A Warm-Up Procedure, Ricardo Parra, Jovanna Bonilla, Elda Padilla, Laura Rodriguez, Naomi Cardenas, Murat Karabulut

International Journal of Exercise Science: Conference Proceedings

Blood Flow Restriction (BFR) training is a novel form of exercise that is emerging as an alternative to traditional resistance training. The research on BFR training as a warm up is limited. PURPOSE: The purpose of this study was to observe the combined effect of a whole body vibration (WBV) warm up and Blood Flow Restriction (BFR) on muscle temperature, flexibility, vertical jump height, and estimated VO2max. METHODS: Nineteen subjects (8 males and 11 females; Mean ± STDEV age = 24.21± 3.47 years; height = 166.94± 8.82 cm) completed the study, which involved performing a warm-up protocol under …

Changes In Health And Physical Fitness Parameters After 6 Months Of High-Intensity Group Exercise In Firefighters: Preliminary Data, Matthew L. Sokoloski, Ryan A. Gordon, Gena D. Guerin, Isaac F. Rowland, Emily L. Zumbro, C Ryan Bachik, B Rhett Rigby

International Journal of Exercise Science: Conference Proceedings

The physical demands of firefighting require the men and women employed in this profession to be in optimal physical condition to perform their jobs proficiently, as well as to mitigate the risk of injury. Every year, the city of Addison, TX, budgets many thousands of dollars to the compensation plan for first responders. Most of the funding is used for rehabilitation services due to work related injuries. PURPOSE: While many of these injuries are unavoidable due to the inherent risks of the profession, ensuring proper physical fitness is one of the most effective methods to reduce many of these impairments. …

Case Presentation For Pigmented Villonodular Synovitis (Pvns), Maria G. Zamora, Tal Amasay, Matthew L. Santos-Vitorino

International Journal of Exercise Science: Conference Proceedings

CASE HISTORY: The patient is a 21 years old male collegiate baseball player who suffered an acute pain in his right knee during practice. The athlete began to experience pain while decelerating following running to first base. Immediately after the occurrence, the athlete’s knee was “locked” and the athlete was unable to perform active knee flexion or extension. Passively, he was unable to flex or extend due to pain. Following the event, there was an immediate swelling of the knee. The athlete had not complained of pain in his knee prior to this date, but mentioned his knee would occasionally …

Effects Of Caffeine Dose Timing On Total Urine Excretion During Sodium-Aided Hyperhydration Protocols, Shelby L. Greene, David M. Morris

International Journal of Exercise Science: Conference Proceedings

When used alone, both caffeine and sodium-aided hyperhydration (SAH) can be ergogenic. Although caffeine use in conjunction with SAH promotes diuresis, hyperhydration can be achieved, albeit at lower levels compared to SAH alone. Previous caffeine and SAH work has suggested most of the caffeine induced diuresis occurs within 15 min of consumption of a bolus of caffeine, sodium and water. This response suggests that caffeine-induces diuresis for only 15 min following its consumption, and/or that the diuretic effects of caffeine are dependent on hydration levels. PURPOSE: To determine the effects of caffeine, consumed at different time-points, on diuresis during SAH …

Case Presentation For Suprascapular Neuropathy, Samantha N. Day, Tal Amasay, Scott Freer

International Journal of Exercise Science: Conference Proceedings

CASE HISTORY: The patient is an 18-year-old female collegiate volleyball player who has suffered progressive shoulder pain in her right shoulder. She states that the pain has progressively gotten worse over the past 3-4 years. The sharp pain began when she would raise her right arm above 90 degrees when hitting an overhand serve. Over time, the pain progressed and became noticeable in additional movements. The patient had noted significant weakness in both her right arm and right shoulder. The patient states when she sleeps on her right arm/shoulder she wakes up in severe pain. She has tried sleeping …

Validity Of Four-Compartment Model Body Fat Using Single- Or Multi-Frequency Bioelectrical Impedance Analysis To Estimate Body Water, M. Lane Moore, Marqui L. Benavides, Jacob R. Dellinger, Brian T. Adamson, Claire P. Underwood, Tyler C. Dierolf, Grant M. Tinsley

International Journal of Exercise Science: Conference Proceedings

Most common body composition assessment techniques make assumptions about the body, including the density and hydration of fat-free mass (FFM). An advantage of the four-compartment (4C) model is the ability to take these FFM characteristics into account when assessing body composition, thus reducing potential error. The total body water (TBW) estimate utilized in 4C models is particularly important due to the large contribution of water to an adult human’s total body mass (~40 - 70%) and FFM (~68 - 81%); however, the impact of utilizing different estimates of TBW within 4C model has not been fully explored. PURPOSE: The …

Comparison Of Regional Body Composition Estimates Obtained From Dual-Energy X-Ray Absorptiometry And Single-Frequency Bioelectrical Impedance Analysis, Jacob Dellinger, M. Lane Moore, Marqui L. Benavides, Tyler C. Dierolf, Brian T. Adamson, Claire P. Underwood, Grant M. Tinsley

International Journal of Exercise Science: Conference Proceedings

The anatomical distribution of fat mass (FM) and lean mass (LM) is significant for health and athletic performance. Dual-energy x-ray absorptiometry (DXA) is often used for regional body composition analysis but is not portable, often inaccessible, and costly, while single-frequency bioelectrical impedance analysis (SFBIA) is a more affordable and accessible alternative. PURPOSE: The purpose of this analysis was to compare regional body composition estimates obtained via DXA and SFBIA. METHODS: After an overnight food and fluid fast, 102 adults (64 F, 38 M; age: 29.2 ± 13.4 y; BMI: 24.3 ± 3.9 kg/m²; BF%: 24.6 ± …

Validity Of Infrared 3-Dimensional Scanning For Estimation Of Body Composition: A 4-Compartment Model Comparison, Brian T. Adamson, Jacob R. Dellinger, Marqui L. Benavides, M. Lane Moore, Claire P. Underwood, Tyler C. Dierolf, Grant M. Tinsley

International Journal of Exercise Science: Conference Proceedings

Multiple infrared 3-dimensional (3D) scanning technologies exist, including time of flight (ToF) scanners and structured light scanners with static (SL-S) and dynamic (SL-D) configurations. ToF scanners measure depth by using the round-trip time of reflected photons, whereas SL scanners measure deformations in light patterns and allow for creation of a depth image using geometric triangulation. Recently, 3D scanning technologies have been proposed as novel methods of body composition assessment. PURPOSE: The purpose of this analysis was to examine the validity of four different commercially-available 3D scanners for estimation of body fat percentage (BF%) as compared to a 4-compartment (4C) …

Circulating Inflammatory And Oxidative Stress Responses To Steady-State Moderate-Intensity And High-Intensity Interval Exercise In Mid-Spectrum Chronic Kidney Disease, Matthew Peterson, Jeffrey S. Forsse, James K. Taylor, Zach Papadakis, Nick Schwedock, Burritt Hess, Jackson O. Griggs Md, Crawford Allison, Ron Wilson Md, Kathleen Adair, Mitch Cholewinski, Peter Grandjean

International Journal of Exercise Science: Conference Proceedings

Inflammation and oxidative stress can be potent modulators of vascular function. These factors may transiently respond to moderate-intensity steady state exercise (SSE) in a manner that improves post-exercise vascular function in healthy adults. Whether exercise imparts similar effects in adults with Stage 3 or 4 chronic kidney disease (CKD) remains understudied. Moreover, a comparison of SSE and high-intensity interval exercise (HIIE) may add to clinically-relevant findings for improving vascular function in mid-spectrum CKD. PURPOSE: To determine the influence of SSE and a comparable amount of HIIE on post-exercise inflammation and oxidative stress in patients diagnosed with secondary Stage 3 or …

The Effect Of Varying High-Intensity Interval Training Style Warm-Ups On Hemodynamic, Power, And Flexibility Responses, Nelson Wise, Orlando Cepeda, Klarissa Ybarra, Brenda Palma, Brianna Lopez, Manuel Nunez, Ezra Meza, Alexandria Hinojosa, Amanda Hankins, Murat Karabulut

International Journal of Exercise Science: Conference Proceedings

PURPOSE: The purpose of this study was to examine the effectiveness of high-intensity interval training (HIIT) style warm-up on hemodynamic, power, and flexibility responses. METHODS: Twelve male subjects (age: 24.15 ± 3.1 yr. & weight: 78.78 ± 16.83 kg) completed the study. On the first day, initial screening, anthropometric measures, and familiarization with testing procedures were completed. There were a total of 6 randomized testing sessions (separated by at least 48 hours.). The testing sessions were as follows: 3-min warm-up session with 20 sec work followed by 10 sec (C1), 3-min warm-up session with 30 sec work followed …

Mental Health Best Practices In Ncaa: The Bidirectional Relationship Between Mental Toughness And Self-Compassion, R. Noah Padgett, Jeffrey S. Forsse, Zacharias Papadakis, Paul J. Deal, Andreas Stamatis Dr.

International Journal of Exercise Science: Conference Proceedings

Based on National Collegiate Athletic Association (NCAA) reports, student-athletes’ well-being is compromised by sub-clinical issues of mental health (MH) disorders, such as depression and anxiety. Preliminary data have shown a positive relationship between mental toughness (MT) and MH, self-compassion (SC) and MH, and SC and MT. To date, possible indirect causal relationships between these three constructs have not been investigated. PURPOSE: To confirm the three aforementioned relationships in NCAA athletes and explore the mediation role of MT and SC on the SC-MH and MT-MH relationships, respectively. Hypotheses: (1) MT will correlate positively with MH, (2) SC will correlate positively …

Muscle Glycogen Depletion And Replenishment: A Meta-Analytic Review, Ian Macklin, Frank Wyatt, Malaeni Ramos, Grant Ralston

International Journal of Exercise Science: Conference Proceedings

Muscle glycogen depletion and replenishment rates have been associated with sport performance, biomechanical movement and immune system alterations. PURPOSE: the purpose of this study is to determine, through a meta-analytic review, the mechanisms of muscle glycogen depletion and replenishment. METHODS: A systematic literature review and meta-analysis research design was utilized. Inclusion-exclusion criteria were the following: Glycogen depletion- replenishment studies; subjects in studies had no pathologies; human and animal studies were accepted; Studies with diet manipulation were accepted; articles accepted for coding were peer reviewed, original publications. Coded studies were summarized and statistically analyzed. Coded variables were presented as …

Renal Function Responses To Steady-State Moderate-Intensity And High-Intensity Interval Exercise In Mid-Spectrum Chronic Kidney Disease, Kathleen E. Adair, Jeffrey S. Forsse 4681817, Matthew Peterson, Zacharias Papadakis, Mitch Cholewinski, Peter Grandjean

International Journal of Exercise Science: Conference Proceedings

Efficacy of exercise to improve renal function remains understudied in adults with mid-spectrum chronic kidney disease (CKD). In addition, a comparison of steady-state exercise (SSE) and high-intensity interval exercise (HIIE) may contribute clinically-relevant information for exercise-related augmentation of renal function in mid-spectrum CKD. PURPOSE: To determine the influence of SSE and a comparable amount of HIIE on indicators of post-exercise renal function in patients diagnosed with secondary Stage 3 or 4 CKD. METHODS: Twenty participants (n = 6 men; n = 14 women; age 62.0 + 9.9 yr; weight 80.9 + 16.2 kg; body fat 37.3 + 8.5% …

A Survey Study Of Self-Rated Patients' Knowledge About Aki In A Post-Discharge Aki Clinic, Victor M. Ortiz-Soriano, Joseph L. Alcorn Iii, Xilong Li, Madona Elias, Taha Ayach, B. Peter Sawaya, Hartmut H. Malluche, Ron Wald, Samuel A. Silver, Javier A. Neyra

Internal Medicine Faculty Publications

Background: Survivors of acute kidney injury (AKI) are at risk of adverse outcomes. Post-discharge nephrology care may improve patients’ AKI knowledge and prevent post-AKI complications.

Objective: The purpose of this study was to examine patients’ awareness about their AKI diagnosis and self-rated knowledge and severity of AKI before and after their first post-discharge AKI Clinic encounter.

Design: We conducted a pre- and post-survey study among AKI survivors who attended a post-discharge AKI Clinic.

Setting: AKI Clinic at the University of Kentucky Medical Center (October 2016 to December 2017). Education about AKI was based on transformative learning theory and provided through …

Maternal And Gestational Influences On Childhood Blood Pressure., Bonita Falkner

Department of Medicine Faculty Papers

Exposures that contribute to a sub-optimal intrauterine environment can have an effect on the developing fetus. Impaired fetal growth that results in low birth weight is an established risk factor for cardio-metabolic disorders later in life. Recent epidemiologic and prospective cohort studies that include the maternal and gestational period have identified maternal and gestational conditions that confer increased risk for subsequent cardio-metabolic disorders in the absence of low birth weight. Maternal pre-conception health status, including chronic obesity and type 2 diabetes, increase risk for childhood obesity and obesity-related higher blood pressure (BP) in child offspring. Maternal gestational exposures, including gestational …

Development And Validation Of The Fsiq-Rms: A New Patient-Reported Questionnaire To Assess Symptoms And Impacts Of Fatigue In Relapsing Multiple Sclerosis, Stacie Hudgens, René Schüler, Jonathan Stokes, Sonya Eremenco, Elke Hunsche, Thomas P. Leist

Department of Neurology Faculty Papers

Objectives: A new patient-reported outcome (PRO) instrument to measure fatigue symptoms and impacts in relapsing multiple sclerosis (RMS) was developed in a qualitative stage, followed by psychometric validation and migration from paper to an electronic format.

Methods: Adult patients with relapsing-remitting multiple sclerosis (RRMS) were interviewed to elicit fatigue-related symptoms and impacts. A draft questionnaire was debriefed in cognitive interviews with further RRMS patients, and revised. Content confirmation interviews were conducted with patients with progressive-relapsing multiple sclerosis (PRMS) and relapsing secondary-progressive multiple sclerosis (RSPMS). Psychometric analyses used data from adult patients with different RMS subtypes and matched non-RMS controls in …

Atraumatic Splenic Rupture Associated With Apixaban., Sijan Basnet, Elan Mohanty, Izza Mir, Rashmi Dhital, Ajay Koirala, Niranjan Tachamo

Reading Hospital Internal Medicine Residency

Apixaban is a direct oral anticoagulant that works by inhibiting factor Xa. It has been associated with adverse bleeding outcomes including atraumatic splenic rupture. We present the case of an 86-year-old man who presented with features of left upper abdominal pain and hemorrhagic shock found to have atraumatic splenic rupture and hemoperitoneum on imaging.

Ephrin-B3 Controls Excitatory Synapse Density Through Cell-Cell Competition For Ephbs., Nathan T. Henderson, Sylvain J. Le Marchand, Martin Hruska, Simon Hippenmeyer, Liqun Luo, Matthew B. Dalva

Department of Neuroscience Faculty Papers

Cortical networks are characterized by sparse connectivity, with synapses found at only a subset of axo-dendritic contacts. Yet within these networks, neurons can exhibit high connection probabilities, suggesting that cell-intrinsic factors, not proximity, determine connectivity. Here, we identify ephrin-B3 (eB3) as a factor that determines synapse density by mediating a cell-cell competition that requires ephrin-B-EphB signaling. In a microisland culture system designed to isolate cell-cell competition, we find that eB3 determines winning and losing neurons in a contest for synapses. In a Mosaic Analysis with Double Markers (MADM) genetic mouse model system in vivo the relative levels of eB3 control …

Organizational Wellness Programs As Internal Social Marketing: A Literature Review Of Feasible Approaches, Faith Bontrager Rn, Bsn, Kimball P. Marshall Ph.D.

Atlantic Marketing Association Proceedings

No abstract provided.

Cisize Version 1.0, Sas-Based Freeware (And Accompanying Manual), M. R. Jiroutek

Pharmaceutical Sciences

created from code written

for dissertation. Based on the methodology presented in Jiroutek, et al. (2003), the software computes exact target probabilities of interest (including power) for any scalar parameter in a General Linear Multivariate Model (GLMM) with Gaussian errors and fixed predictors. Consisting of a single SAS IML module, this software focuses on sample size computations for studies aims at estimating a confidence interval.

The Nights Of Our Lives: Why We Sleep & Dream, Jaime L. Tartar Phd

Faculty Proceedings, Presentations, Speeches and Lectures

Explore the most recent theories and evidence of why we sleep, and what happens in the brain during sleep and the consequences of sleep loss and sleep disorders.

A Comparison Of The Polytomous Rasch Analysis Output Of Rumm2030 And R (Ltm/Erm/Tam/Lordif), Michael Robinson, Andrew M. Johnson, David M. Walton, Joy C. Macdermid

Bone and Joint Institute

© 2019 The Author(s). Background: Patient-reported outcome measures developed using Classical Test Theory are commonly comprised of ordinal level items on a Likert response scale are problematic as they do not permit the results to be compared between patients. Rasch analysis provides a solution to overcome this by evaluating the measurement characteristics of the rating scales using probability estimates. This is typically achieved using commercial software dedicated to Rasch analysis however, it is possible to conduct this analysis using non-specific open source software such a R. Methods: Rasch analysis was conducted using the most commonly used commercial software package, RUMM …

Do Hospital Closures Affect Patient Time In An Ambulance?, Suzanne Troske, Alison Davis

Rural & Underserved Health Research Center Publications

When a hospital closes in a community, patients needing emergency care may spend more time in an ambulance to receive care in an emergency department (ED). We explore how hospital closures affect the time a patient travels from an incident location where 9-1-1 was called to the ED in an ambulance.

• Rural patients average an estimated 11 additional minutes in an ambulance the year after a hospital closure in their zip code, a 76% increase compared to before the closure.
• Urban and suburban patients have no change in transportation time in zip codes where a hospital closes.
• Patients over 64 …

Astrocytes Infected With Chlamydia Pneumoniae Demonstrate Altered Expression And Activity Of Secretases Involved In The Generation Of Β-Amyloid Found In Alzheimer Disease, Zein Al-Atrache, Danielle B Lopez, Susan Hingley, Denah Appelt

PCOM Scholarly Works

BACKGROUND: Epidemiologic studies strongly suggest that the pathophysiology of late-onset Alzheimer disease (AD) versus early-onset AD has environmental rather than genetic causes, thus revealing potentially novel therapeutic targets to limit disease progression. Several studies supporting the "pathogen hypothesis" of AD demonstrate a strong association between pathogens and the production of β-amyloid, the pathologic hallmark of AD. Although the mechanism of pathogen-induced neurodegeneration of AD remains unclear, astrocytes, a key player of the CNS innate immune response and producer/metabolizer of β-amyloid, have been implicated. We hypothesized that Chlamydia pneumoniae infection of human astrocytes alters the expression of the amyloid precursor protein …

The Population Health Template: A Roadmap For Successful Health Improvement Initiatives, Michael Kobernick, Md, Ms-Hsa, Ms-Poph, Faafp

Population Health Leadership Series: PopTalk Webinars

Learning Objectives

• Describe the population health template as a tool to achieve and report on Quintuple Aim objectives of health improvement initiatives
• Identify gaps in current health initiatives illustrating the needs for the template's more organized approach
• Apply the template to health improvement opportunities in health improvement initiatives
• Understand the role of social determinants of health in health improvement initiatives

Presentation: 50:31

Spatial-Temporal Variability Of In Situ Cyanobacteria Vertical Structure In Western Lake Erie: Implications For Remote Sensing Observations, Karl Bosse, Michael Sayers, Robert Shuchman, Gary L. Fahnenstiel, Steven A. Ruberg, David L. Fanslow, Dack G. Stuart, Thomas H. Johengen, Ashley M. Burtner

Michigan Tech Publications, Part 1

Remote sensing has provided expanded temporal and spatial range to the study of harmful algal blooms (cyanoHABs) in western Lake Erie, allowing for a greater understanding of bloom dynamics than is possible through in situ sampling. However, satellites are limited in their ability to specifically target cyanobacteria and can only observe the water within the first optical depth. This limits the ability of remote sensing to make conclusions about full water column cyanoHAB biomass if cyanobacteria are vertically stratified. FluoroProbe data were collected at nine stations across western Lake Erie in 2015 and 2016 and analyzed to characterize spatio-temporal variability …

A Closer Look At Arsa Activity In A Patient With Metachromatic Leukodystrophy., Kathleen Doherty, S. Barron Frazier, Matthew Clark, Anna Childers, Sumit Pruthi, David A. Wenger, Jessica Duis

Department of Neurology Faculty Papers

Metachromatic leukodystrophy (MLD) is an autosomal recessive lysosomal storage disease mainly caused by a deficiency of arylsulfatase A activity. The typical clinical course of patients with the late infantile form includes a regression in motor skills with progression to dysphagia, seizures, hypotonia and death. We present a case of a 4-year-old female with rapidly progressive developmental regression with loss of motor milestones, spasticity and dysphagia. MRI showed volume loss and markedly abnormal deep white matter. Enzymatic testing in one laboratory showed arylsulfatase A activity in their normal range. However, extraction of urine showed a large increase in sulfatide excretion in …