Medicine and Health Sciences Commons^™

Electronic Cigarettes In The Indoor Environment, Cheryl Marcham

Publications

This presentation covers the development of electronic cigarettes and presents statistics related to their manufacture and use. Also included are facts about how addictive the products are, especially to young people, who are particularly vulnerable to addiction. The FDA has begun work to end sales of e-cigarette products to minors. Included in the presentation are formulae for the various vaping products, which are not healthy for users or people in their vicinity. Telephone calls to poison call centers increased drastically from 2010 to 2014.

Faculty Socialization Of Graduate Students’ Attitudes And Perceptions Toward The Irb, Elisa Jolls

Electronic Theses and Dissertations

Graduate student mistrust and fear of the institutional review board (IRB) is an issue that is commonly encountered at academic institutions. Research has shown that students emulate and are vulnerable to assuming the norms of faculty, which is supported by research that shows that students who have difficult relationships with the IRB often have faculty mentors who also have difficult relationships with the IRB. The purpose of this qualitative case study was to explore how novice researchers’ perceptions of the IRB changed through their research submission and IRB interactions required during the IRB approval process, as well as to identify …

Medical School Watercooler Newsletter - March 3, 2019, Lindsey Lyle

Watercooler Newsletter

This is the March 3, 2019 edition of the Frederick P. Whiddon College of Medicine's Newsletter - Watercooler.

Contents Include:

Dr. Allen Perkins named president-elect of ADFM

Shamshur, Shamshur, Tsos

TSOS Interview Gallery

Shamshur has been in Cox’s Bazaar for 8 months and works in Hope Hospital (the camp hospital) as a traditional birth attendant. In addition, she makes house calls to pregnant women throughout the camp who are fearful of hospitals due to past trauma and sexual torture. Shamshur has nine children and a husband who is in prison.

Modina, Modina, Tsos

TSOS Interview Gallery

Modina fled Myanmar after experiencing and witnessing extreme violence, including the destruction of her village and the violent murder of her uncle by soldiers. She arrived in Bangladesh by boat after paying smugglers a large sum.

Nidar, Nidar, Tsos

TSOS Interview Gallery

Nidar has been in Cox’s Bazaar for 8 months and works in Hope Hospital (the camp hospital) as a traditional birth attendant. In addition, she makes house calls to pregnant women throughout the camp who are fearful of hospitals due to past trauma and sexual torture. Nidar has two children and a husband who fell victim to war.

Asma, Asma, Tsos

TSOS Interview Gallery

Asma is a teenager who fled from Myanmar after the army killed her uncle and her village was destroyed. She is now living in Cox’s Bazaar, married, pregnant, and trying to cope in a world where violence and rape are all too common.

Cystatin C And Risk Of New-Onset Depressive Symptoms Among Individuals With A Normal Creatinine-Based Estimated Glomerular Filtration Rate: A Prospective Cohort Study, Li Haibin, Wang Anxin, Qi Gao, Guo Jin, Li Xia, Wei Wang, Xiang Yutao, Guo Xiuhua

Research outputs 2014 to 2021

The association between cystatin C and depressive symptoms in the general population has not been thoroughly elucidated to date. We investigated the association of cystatin C with new-onset depressive symptoms among individuals with normal creatinine-based estimated glomerular filtration rates (eGFR). In the China Health and Retirement Longitudinal Study, 5111 participants without depressive symptoms or renal dysfunction (eGFR < 60 ml/min/1.73 m

Table Of Contents

Journal of the South Carolina Academy of Science

No abstract provided.

New Insights On Age-Related Hearing Loss, Judy R. Dubno

Journal of the South Carolina Academy of Science

No abstract provided.

Best Practices For Long-Term Monitoring And Follow-Up Of Alemtuzumab-Treated Ms Patients In Real-World Clinical Settings., Krista Barclay, Robert Carruthers, Anthony Traboulsee, Ann D Bass, Christopher Laganke, Antonio Bertolotto, Aaron Boster, Elisabeth G Celius, Jérôme De Seze, Dionisio Dela Cruz, Mario Habek, Jong-Mi Lee, Volker Limmroth, Sven G Meuth, Celia Oreja-Guevara, Patricia Pagnotta, Cindy Vos, Tjalf Ziemssen, Darren P Baker, Bart Van Wijmeersch

Neuroscience Articles

Multiple sclerosis (MS) is a chronic autoimmune neurological disease that typically affects young adults, causing irreversible physical disability and cognitive impairment. Alemtuzumab, administered intravenously as 2 initial courses of 12 mg/day (5 consecutive days at baseline, and 3 consecutive days 12 months later), resulted in significantly greater improvements in clinical and MRI outcomes vs. subcutaneous interferon beta-1a over 2 years in patients with active relapsing-remitting MS (RRMS) who were either treatment-naive (CARE-MS I; NCT00530348) or had an inadequate response to prior therapy (CARE-MS II; NCT00548405). Efficacy with alemtuzumab was maintained over 7 years in subsequent extension studies (NCT00930553; NCT02255656), in …

The Effect Of Sensory Input On The Temporal Structure Of Center Of Pressure In Stroke Survivors, Samantha Chong

UNO Student Research and Creative Activity Fair

Stroke is the leading cause of disability that affects 17 million people worldwide. Patients post stroke suffer from maintaining balance because the brain may not be able to receive or process visual, vestibular and proprioceptive sensory information: all of which contribute towards maintaining stability. Information provided by vision is important for spatial orientation, as it develops an environmental perspective. Proprioception is detected through the stretching of tendonsand surrounding tissue, and is able to help the brain determine spatial location. The vestibular system provides the sense of balance detecting rotations and linear accelerations through the vestibulo-ocular reflex. The vestibular system is …

How The Foot Modulates Its Mechanics During Uphill And Downhill Walking, Jeffrey M. Patterson, Kota Z. Takahashi

UNO Student Research and Creative Activity Fair

The foot's biomechanical role in walking on sloped surfaces is currently unclear. While previous biomechanics studies have examined the hip, knee, and ankle, the foot is oversimplified as a rigid-body segment. This oversimplification overshadows its complex structure and function. In this project, we use an innovative multi-segment foot model to explore how the foot adapts its mechanics to incline and decline walking. Preliminary results have revealed that the foot is capable of adapting its mechanical work profile to both incline and decline walking. Specifically, the foot can increase its positive work output (i.e., increased energy generation) during inclined walking to …

Updates On Epigenetic Alterations To Brca1: Chemosensitivities, Haley Blum

UNO Student Research and Creative Activity Fair

Breast cancer 1, early onset (BRCA1) is a human tumor suppressor gene encoding the BRCA1 protein that maintains genomic integrity. Molecular events may contribute to the loss of BRCA1 function, contributing to site specific tumorigenesis. Loss of BRCA1 function may arise from mutation or epigenetic events. Germline mutations of BRCA1 have been thoroughly implicated in heritable breast and ovarian cancers. More recently, sporadic breast cancer has been shown to be driven by epigenetic alterations to the BRCA1 promoter region, specifically methylation. Breast carcinomas that present with BRCA1 promoter methylation have been associated with triple negative breast cancers, as well …

Developing And Testing Of An Upper Limb Exoskeleton For Stroke Patients, Drew Dudley, David Salazar

UNO Student Research and Creative Activity Fair

Objective: The main objective of this study was to determine functional and neuromuscular outcomes of stroke patients using their non-preferred hand with and without a 3D printed passive exoskeleton compared to controls using their non-preferred hand with and without the passive exoskeleton. Methods: Adults at least six months post stroke (Stroke, n = 5) and age- and sex- matched healthy controls (Control, n = 5) performed nine trials of a gross motor task while having their brain activity measured. The Fugl-Meyer and “Box and Block” test was used to measure the gross dexterity of the subjects with and without the …

An Exploration Of Why Healthcare Professionals Under-Report Observed Patient Aggression, Sydney Bonta

UNO Student Research and Creative Activity Fair

An Exploration of Why Healthcare Professionals Under-Report Observed Patient Aggression

Authors: Sydney Bonta & Lisa L. Scherer, Ph.D.

Advisor: Lisa L. Scherer, Ph.D.

According to the 2011 US Bureau of Justice Statistics report, medical professionals experienced the third highest proportion of workplace violence (WPV), with violence primarily emanating from patient. In a national survey of nurses employed in hospitals, 76% stated that they had encountered some sort of violence in their workplace (Speroni, Fitch, Dawson, Dugan, Atherton, & Leesburg, 2014). Similarly, patient aggression against physicians has long been a problem (Morrison, Lantos, Levinson, 1998). Despite this widespread exposure to WPV …

Efficacy Of Assistive Devices Produced With Additive Manufacturing, James Pierce

UNO Student Research and Creative Activity Fair

Despite the frequency of musculoskeletal injuries such as sprains, broken bones and torn ligaments¹, treatment options are often costly, time-consuming and ill-fitted.^2,3 Additive manufacturing (“3D-printing) allows for the production of highly-customized and inexpensive assistive devices⁴, which suggests potential efficacy in the prescription of splints and casts for musculoskeletal injury.³ In the present study, a parametric, customizable splint/cast was created using a computer-aided design (CAD) package (Fusion 360, Autodesk, San Rafael, CA, USA) and produced with low-cost, desktop 3D printing (Ultimaker 2+ Extended, Ultimaker, Geldermalsen, Netherlands). Fitting of the devices was performed on five healthy …

The Opioid Crisis: Exploring The Effects On First Responders And Healthcare Professionals, Rachel Lubischer, Dawne Frain

UNO Student Research and Creative Activity Fair

In 2017, the National Department of Health and Human Services declared the opioid crisis a public health emergency (The White House, 2018). Although Nebraska ranks among the states with the lowest number of drug overdose deaths, rising opioid use creates safety concerns for first responders and healthcare professionals, and leads to strained resources in many jurisdictions. We hope to increase our audience’s knowledge on the opioid crisis, how it effects first responders and healthcare professionals, and pertinent policies and initiatives in Nebraska. Our audience will leave this presentation better equipped to initiate discussions with friends, family, and community members about …

Evaluating An Electronic Protocol In A Pediatric Intensive Care Unit, Jeanette Rose

UNO Student Research and Creative Activity Fair

A team of clinicians at Children’s Hospital and Medical Center (CHMC) developed a standardized protocol in 2018 for the care of patients needing sedation. This protocol is ordered through the EPIC electronic health record system for patients in the pediatric intensive care unit (PICU). When used, electronic protocols reduce the variation in clinical decision making which can ultimately improve patient outcomes. The goal of this project is to evaluate this technology, how the protocol is being used, and how it may be improved. Actual users of the EPIC sedation protocol were the subjects of this study, including PICU physicians, physician …

Temporal Step Coordination While Walking With A Single-Point Cane, Monica Barajas

UNO Student Research and Creative Activity Fair

TEMPORAL STEP COORDINATION WHILE WALKING WITH A SINGLE-POINT CANE

Monica Barajas, Russel Buffum, Tyler Hamer, Brian A. Knarr

University of Nebraska at Omaha, Omaha, NE

Stroke is the primary cause of long-term adult disability in the United States. Some physical limitations that a stroke survivor may encounter are foot drop, unilateral muscle weakness, limited coordination and muscle movement, among other effects that may directly affect gait. To address weakness and poor coordination post-stroke, a cane is commonly used. While a cane can help with balance, coordinating steps with an additional device can prove difficult to learn and may alter natural …

Visual Contributions To Balance Control During Gait, Kyle Brozek

UNO Student Research and Creative Activity Fair

We propose to isolate the contributions of continuous OF to the orthogonal relationship between balance and gait control during treadmill walking using a series of conditions. Manipulating the direction of OF using a CAREN (Motek Medical, Amsterdam, Netherlands) virtual reality treadmill environment will isolate these visual contributions in human subjects as they walk. We plan to tease out the effect of OF direction on the relationship between gait and balance control by having healthy young adults perform a series of treadmill walking trials while immersed in a VR environment. This will be done by manipulating the direction of walking and …

The Effect Of Arm Swing On Countermovement Vertical Jump Performance, Arash Mohammadzadeh Gonabadi

UNO Student Research and Creative Activity Fair

Vertical jumping is one of the popular ways to evaluate ankle-knee efficiency in athletic population. Arm swing can play a crucial role in enhancing vertical jump performance. This study aimed to address the differences in kinetic and kinematic parameters during countermovement jump motion with arm swing (AS) and no arm swing (NAS). We used OpenSim to examine the efficacy of AS in reducing the impulse applied to the body and changes in range of lower limb joint angles at landing instant. We calculated the maximum vertical peak of the ground reaction force and impulse generated at landing in two different …

Gait Alterations In Peripheral Arterial Disease Are Not Worsened By The Presence Of Diabetes, Hafizur Rahman

UNO Student Research and Creative Activity Fair

Peripheral arterial disease (PAD) is a vascular disease where atherosclerotic blockages restrict blood flow to muscles in the lower extremities. Diabetes is a common co-morbid condition in PAD and has been shown to increase the risk of lower extremity amputation compared to PAD without diabetes. Although there is a clear pathological relationship between diabetes and PAD, the gait mechanics involved remain indistinct. Therefore, the purpose of this study was to determine whether the presence of diabetes in addition to PAD results in greater functional impairment during ambulation. Twenty-three subjects with PAD and twelve controls consented to participate in the research. …

Diagnostic Accuracy Of Instrumented Helmets To Assess Concussions In High School Football Athletics, Alyssa Irby

UNO Student Research and Creative Activity Fair

Approximately 300,000 high school students experience a concussion yearly and are the third most common injury for youth football players accounting for 9.6% of all injuries. The current concussion monitoring systems are subjective and rely heavily on symptom recognition by players and coaches. Instrumented helmets fill a gap when subjective monitoring systems fail to recognize concussions. The purpose of this study is to determine the diagnostic accuracy of instrumented helmets and the effectiveness of alerting for a concussion in a youth population. Fifty-five football players from a local high school during the 2018 season who wore instrumented helmets participated. Impact …

The Effects Of A 12-Week Jump Rope Exercise Program On Abdominal Adiposity, Vasoactive Substances, Inflammation & Vascular Function In Prehypertensive Adolescent Girls, Ronald Headid

UNO Student Research and Creative Activity Fair

Childhood obesity is strongly associated with cardiovascular disease (CVD) development. It is necessary to combat unfavorable outcomes of obesity at a young age by utilizing effective interventions, such as exercise. Purpose: We sought to examine the effects of a jump rope exercise program on CVD risk factors, including body composition, vasoactive substances, inflammation, and vascular function in prehypertensive adolescent girls. Methods: Forty girls (age 14-16) were recruited and randomly assigned to a jump rope exercise group (EX, n=20) or control group (CON, n=20). Body composition, nitrate and nitrite levels, endothelin-1 (ET-1), c-reactive protein (CRP), systolic blood pressure and diastolic blood …

The Effects Of Swimming Training On Arterial Stiffness, Muscular Strength And Cardiorespiratory Endurance In Postmenopausal Women With Stage 2 Hypertension, Steven Scott

UNO Student Research and Creative Activity Fair

Objective:

Aging is associated with progressive decreases in arterial health and function as well as overall fitness. It is crucial to prevent or reduce the negative effects of aging on vasculature and fitness components by implementing appropriate lifestyle interventions, such as exercise training. We examined the effects of a swimming (SWM) regimen on arterial stiffness (pulse wave velocity, PWV), blood pressure (BP), wave reflection (AIx), muscle strength and aerobic capacity in postmenopausal women with stage 2 hypertension.

Methods:

Using a parallel experimental design, participants were randomly assigned to either a SWM (n=52) or non-exercising control group (n=48) for 20 weeks. …

Division I Collegiate Male Basketball Player Post-Surgical Cai With Bone Spur Excision: A Case Report, Jacqueline Gutierrez

UNO Student Research and Creative Activity Fair

A Division I basketball player planted his foot and injured his ankle. He had a significant history of repeated lateral ankle sprains and was evaluated as having a grade 2 ankle sprain. He was referred for imaging revealing significant damage to a variety of tissues including a talar osteochondral defect and joint degeneration. He opted for surgical repair, however, post-surgical rehabilitation did not improve the athlete and a secondary procedure was necessary to correct complications. The initial procedure was successful to repair ligamentous stability of the joint. But was not sufficient to fully restore the joint to full function.

Investigating The Effect Of Induced Stress On Dual-Task Performance, Farahnaz Fallah Tafti

UNO Student Research and Creative Activity Fair

Doing two tasks concurrently is an inevitable situation that occurs in daily life. Several factors such as pathological conditions, the aging process, and even stress may have a detrimental effect on both tasks’ performances. The aim of this study was to monitor perceived stress during dual-task to investigate how inducing stress affects dual-task performance. Eighteen healthy young participants, (24.76±3.56 years; 68.85 ±11.85 kg; 1.72±0.07 m) were recruited. Participants were asked to perform a single task (no secondary task) and DTs (wire maze with or without buzzer) randomly while standing on a firm surface. Perceived stress was obtained after each trial …

Estimating Variations In Metabolic Cost Within The Stride Cycle During Level And Uphill Walking, Arash Mohammadzadeh Gonabadi

UNO Student Research and Creative Activity Fair

Indirect calorimetry provides the average cost of a stride cycle and prevents from identifying which part of the gait cycle causes increased metabolic cost in patients, however, recent simulation methods allow estimating the time profile of metabolic cost within the stride cycle. In this study, we compare the estimations of the time profile of the metabolic cost of two simulation methods for level and uphill walking. We used kinematic, kinetic and electromyography data from level and uphill walking (one participant) to estimate the time profiles of metabolic cost using the muscle-level metabolic model of Umberger using electromyography and kinematic data …

Impacts Of Exercise And Environmental Temperature On Mitochondrial Quantity And Quality, Halee Keller

UNO Student Research and Creative Activity Fair

Halee Keller, Robert Shute, Dustin Slivka

University of Nebraska at Omaha, School of Health and Kinesiology, Omaha, NE

BACKGROUND: Mitochondria are highly concentrated in skeletal muscle tissue, and undergo damage from ROS during metabolic processes. This damage is often left unrepaired and leads to mitochondrial dysfunction, which has been linked to many common diseases. Exercise training increases mitochondrial development within skeletal muscle tissue and thus may be protective. Environmental temperature, when paired with exercise may provide an even greater effect than exercise alone. PURPOSE: The purpose of this study is to analyze the effects of three weeks of exercise …