Medicine and Health Sciences Commons^™

Entertainment-Related Excessive Sound Exposure (Erese): Associated Audiometric-Threshold Patterns, Ashley Lenard, Antony Joseph

AuD Capstone Projects - Communication Sciences and Disorders

Previous studies have reported that exposure to hazardous sounds can result in a mild to profound degree of temporary and permanent hearing loss. Typically, individuals exposed to loud industrial noise develop a notch or dip at or near the pure-tone test frequency 4,000 Hz. Exposure to hazardous recreational and work-place sound has been associated with noise-induced hearing loss (NIHL) and tinnitus has been associated with exposure to high-intensity concert sound as well. The purpose of this project was to report whether audiometric patterns have been reported in the literature that may be associated with entertainment-related excessive sound exposure (ERESE). Over …

Effects Of Free Maternity Service Policy In Kenya: An Interrupted Time Series Analysis, Evaline Lang'at, L. Mwanri, Marleen Temmerman

Obstetrics and Gynaecology, East Africa

Background: In Kenya, more than 6000 maternal deaths, and 35000 stillbirths occur each year. In June, 2013, the Government of Kenya abolished user fees for maternity care in all public health facilities under the Free Maternity Service (FMS) policy, to make maternity services accessible and affordable, and to reduce maternal and perinatal deaths. This study aims to establish whether the FMS policy has influenced use of, access to, and quality of maternity care in Kenya.

Methods: We did an observational retrospective study in three counties in Kenya. We used daily maternity registers in 90 public health facilities to extract monthly …

Health & Kinesiology News, Georgia Southern University

Health Sciences & Kinesiology: News & Publications (2015-2023)

• Snarr to Co-Edit 3rd Edition of Textbook on Personal Training

College Of Health Professions News, Georgia Southern University

College of Health Professions: News & Publications (2012-2023)

• Dr. Willie J. Burden Memorial Fund Endowed

Best Practice For Preventing Relapse Of Smoking Cessation, Kristen Gourneau

Nursing Capstones

No abstract provided.

Using Electropalatography To Analyze Intra-Speaker Variability In German Second Language Fricative Production, Elizabeth D. Young

Undergraduate Honors Theses

Electropalatography (EPG) is a biofeedback system that tracks tongue contact with the palate during speech. The current study uses EPG data to examine the variability that occurs in speech production for individuals speaking a second language (L2). Five native German speakers and twelve native English speakers learning German as a second language were asked to produce the fricatives [ç], [x], and /ʃ/ in various linguistic contexts. Variability in center of maximal contact across the anterior-posterior dimension (“Center of Gravity” – COG) and duration for L2 production across sound type, L2 production across task type, L2 production across subject, and native …

Mutational Effects Of Human Dopamine Transporter At Tyrosine88, Lysine92, And Histidine547 On Basal And Hiv-1 Tat-Inhibited Dopamine Transport, Wei-Lun Sun, Pamela M. Quizon, Yaxia Yuan, Matthew J. Strauss, Richard Mccain Jr., Chang-Guo Zhan, Jun Zhu

Molecular Modeling and Biopharmaceutical Center Faculty Publications

Dysregulation of dopaminergic system induced by HIV-1 Tat protein-mediated direct inhibition of the dopamine transporter (DAT) has been implicated as a mediating factor of HIV-1 associated neurocognitive disorders. We have reported that single point mutations on human DAT (hDAT) at tyrosine88 (Y88F), lysine92 (K92M), and histidine547 (H547A) differentially regulate basal dopamine uptake but diminish Tat-induced inhibition of dopamine uptake by changing dopamine transport process. This study evaluated the effects of double (Y88F/H547A) and triple (Y88F/K92M/H547A) mutations on basal dopamine uptake, Tat-induced inhibition of DAT function, and dynamic transport process. Compared to wild-type hDAT, the V_max values of [^{3 …}

Transspinal Stimulation Increases Motoneuron Output Of Multiple Segments In Human Spinal Cord Injury, Lynda M. Murray, Maria Knikou

Publications and Research

Targeted neuromodulation strategies that strengthen neuronal activity are in great need for restoring sensorimotor function after chronic spinal cord injury (SCI). In this study, we established changes in the motoneuron output of individuals with and without SCI after repeated noninvasive transspinal stimulation at rest over the thoracolumbar enlargement, the spinal location of leg motor circuits. Cases of motor incomplete and complete SCI were included to delineate potential differences when corticospinal motor drive is minimal. All 10 SCI and 10 healthy control subjects received daily monophasic transspinal stimuli of 1-ms duration at 0.2 Hz at right soleus transspinal evoked potential (TEP) …

Ovalbumin-Sensitized Mice Have Altered Airway Inflammation To Agriculture Organic Dust, Kristi J. Warren, John D. Dickinson, Amy J. Nelson, Todd A. Wyatt, Debra J. Romberger, Jill A. Poole

Journal Articles: Internal Medicine

Agriculture exposures are associated with reducing the risk of allergy and asthma in early life; yet, repeated exposures later in life are associated with chronic bronchitis and obstructive pulmonary diseases. The objective of this study was to investigate the airway inflammatory response to organic dust extract (ODE) in mice with established ovalbumin (OVA)-induced experimental asthma. C57BL/6 mice were either OVA sensitized/aerosol-exposed or saline (Sal) sensitized/aerosol-challenged. Both groups were then subsequently challenged once with intranasal saline or swine confinement ODE to obtain 4 treatment groups of Sal-Sal, Sal-ODE, OVA-Sal, and OVA-ODE. Airway hyper-responsiveness (AHR) to methacholine, bronchiolar lavage fluid, lung tissues, …

Undergraduate Nursing Students’ Knowledge Of Aging, Attitudes Toward And Perceptions Of Working With Older Adults In Kathmandu Nepal, Saruna Ghimire, Nitisha Shrestha, Karen E. Callahan, Dhirendra Nath, Binaya Kumar Baral, Nirmale Lekhak, Devendra Raj Singh

School of Public Health Faculty Research

Objectives: This study aims to examine Nepalese undergraduate nursing students’ knowledge of aging, attitudes towards older adults and perceptions of working with older adults, and to assess differences in these outcomes by socio-demographic characteristics as well as type of nursing program. Methods: A cross-sectional study was conducted among 385 undergraduate nursing students in six nursing colleges located in the Kathmandu Valley. Knowledge of aging, attitudes toward older adults and perceptions of working with older adults were assessed using standardized tools, the Palmore Facts on Aging Quiz, Kogan's Attitudes towards Older People Scale, and Nolan's Intent to Work with Older People …

Undergraduate Nursing Students Knowledge Of Aging, Attitudes Toward And Perceptions Of Working With Older Adults In Kathmandu Nepal, Saruna Ghimire, Nitisha Shrestha, Karen E. Callahan, Dhirendra Nath, Binaya Kumar Baral, Nirmala Lekhak, Devendra Raj Singh

Nursing Faculty Research

Objectives:This study aims to examine Nepalese undergraduate nursing students’knowledge of aging,attitudes towards older adults and perceptions of working with older adults, and to assess differences inthese outcomes by socio-demographic characteristics as well as type of nursing program.Methods:A cross-sectional study was conducted among 385 undergraduate nursing students in sixnursing colleges located in the Kathmandu Valley. Knowledge of aging, attitudes toward older adults andperceptions of working with older adults were assessed using standardized tools, the Palmore Facts onAging Quiz, Kogan's Attitudes towards Older People Scale, and Nolan's Intent to Work with Older PeopleQuestionnaire, respectively.Results:The mean knowledge scores on older adults and aging …

"The Great Debate" 2019 - Brookings V. Unlv Debate Team, Brookings Mountain West, University Of Nevada, Las Vegas

Brookings Scholar Lecture Series

Brookings Mountain West, in partnership with the UNLV Debate Team, was proud to host the inaugural UNLV - Brookings Institution event, “The Great Debate.” Representatives from the nationally ranked UNLV Debate Team engaged colleagues from the Brookings Institution in a battle of ideas and policy positions destined to be remembered as one of the great intellectual forums of the 21st century. Featured speakers participated in a modified format of intercollegiate debate rules that allowed teams and individual members the opportunity to craft their arguments and responses in an open and respectful exchange of information to persuade, inform, and entertain audience …

A Phenomenological Exploration: The Black Bile Of Depression, Charles L. Dunlap Ii, M.A.

Counseling and Family Therapy Scholarship Review

The phenomenon of depression manifests itself in many different forms, haunting us with its simultaneously inescapable, diffuse and pervasive presence. The rich thickness of depression is often severely drained and confined within the overall field of psychology, in which this phenomenon is regularly expressed as an all-encompassing, diagnostic label, to limitedly describe an almost endless number of symptomatic permutations. We shall attempt to distill something of depression’s essence in returning to its ancient, etymological, spiritual and metaphysical roots, in order to begin transcending the traditional clinical notion of depression as simply a disease to be cured and suppressed. The relatively …

The Phenomenal Space Of Soulful Silence, Ellen Wimmer

Counseling and Family Therapy Scholarship Review

Where has silence gone? What does this mean for the spiritual soul? This analysis utilizes a phenomenological and qualitative lens to assess the way silence and the soul interact. The author posits that the relationship between silence and the soul, or soulful silence, creates a space to learn about the powerful phenomena that shape us. Through imagery, metaphor, and personal reflection the author embarks on a descriptive journey to explore what we learn by sitting in soulful silence, the phenomenological and spiritual implications of soulful silence, and how one must first become intimately familiar with their own soulful silence …

Perioperative Venous Thromboembolism Prophylaxis In Prostate Cancer Surgery, Zachary Klaasson, Christopher J.D. Wallis, Luke T. Lavallee, Philippe D. Violette

Department of Medicine Publications

Purpose

To describe a patient and procedure specific approach to selecting Venous thromboembolism (VTE) prophylaxis for men who undergo radical prostatectomy.

Methods

We performed a literature search and narrative review of VTE after radical prostatectomy. We describe the current paradigm of perioperative thromboprophylaxis and underlying rationale. Relevant findings from the European Association of Urology thromboprophylaxis guidelines are interpreted and summarized.

Results

The use of extended post-operative thromboprophylaxis for patients who undergo radical prostatectomy is appropriate when the risk of symptomatic VTE outweighs the risk of major bleeding. Patient and procedure factors impact VTE risk. Patient risk can be stratified as …

Operationalization Of Bi-Directional Screening For Tuberculosis And Diabetes In Private Sector Healthcare Clinics In Karachi, Pakistan, Mashal S. Basir, Shifa Salman Habib, Syed M A. Zaidi, Saira Khowaja, Hamidah Hussain, Rashida A. Ferrand, Aamir J. Khan

Community Health Sciences

Background: Many countries are facing overlapping epidemics of tuberculosis (TB) and diabetes mellitus (DM). Diabetes increases the overall risk of developing Tuberculosis (TB) and contributes to adverse treatment outcomes. Active screening for both diseases can reduce TB transmission and prevent the development of complications of DM. We investigated bi-directional TB-DM screening in Karachi, Pakistan, a country that ranks fifth among high TB burden countries, and has the seventh highest country burden for DM.
Methods: Between February to November 2014, community-based screeners identified presumptive TB and DM through verbal screening at private health clinics. Individuals with presumptive TB were referred for …

Supervised Dimension Reduction For Large-Scale "Omics" Data With Censored Survival Outcomes Under Possible Non-Proportional Hazards, Lauren Spirko-Burns, Karthik Devarajan

COBRA Preprint Series

The past two decades have witnessed significant advances in high-throughput ``omics" technologies such as genomics, proteomics, metabolomics, transcriptomics and radiomics. These technologies have enabled simultaneous measurement of the expression levels of tens of thousands of features from individual patient samples and have generated enormous amounts of data that require analysis and interpretation. One specific area of interest has been in studying the relationship between these features and patient outcomes, such as overall and recurrence-free survival, with the goal of developing a predictive ``omics" profile. Large-scale studies often suffer from the presence of a large fraction of censored observations and potential …

The Effects Of Multi-Tiered Systems Of Language Support On Oral Language, Reading Comprehension, And Writing In Second And Third Grade Students In India, Brenna Scadden Nelson

Undergraduate Honors Theses

This study investigated whether multi-tiered narrative intervention improved oral language comprehension, reading comprehension, and writing in second and third-grade students in India. There were 121 participants across second and third grade. Classrooms were randomly assigned to a treatment, an alternate-treatment, or a no-treatment condition. The treatment group participated in 8 weeks of Story Champs intervention, the alternate-treatment group participated in 8 weeks of shared storybook intervention, and the no treatment group served as a control. Results indicated that oral narrative intervention delivered through a multi-tiered system of language support (MTSLS) causally impacted the oral language, reading comprehension, and narrative writing …

Empowering Hiv-Infected Women In Lowresource Settings: A Pilot Study Evaluating A Patient-Centered Hiv Prevention Strategy For Reproduction In Kisumu, Kenya, Okeoma Mmeje, Betty Njoroge, Pauline Wekesa, Alfred Murage, Raphael O. Ondondo, Sheryl Van Der Poel, Mary A. Guze, Starley B. Shade, Elizabeth A. Bukusi, Deborah Cohan, Craig R. Cohen

Obstetrics and Gynaecology, East Africa

Background: Female positive/male negative HIV-serodiscordant couples express a desire for children and may engage in condomless sex to become pregnant. Current guidelines recommend antiretroviral treatment in HIV-serodiscordant couples, yet HIV RNA viral suppression may not be routinely assessed or guaranteed and pre-exposure prophylaxis may not be readily available. Therefore, options for becoming pregnant while limiting HIV transmission should be offered and accessible to HIV-affected couples desiring children.

Methods: A prospective pilot study of female positive/male negative HIV-serodiscordant couples desiring children was conducted to evaluate the acceptability, feasibility, and effectiveness of timed vaginal insemination. Eligible women were 18-34 years with regular …

Combining Radiation And Immune Checkpoint Blockade In The Treatment Of Head And Neck Squamous Cell Carcinoma., Gregor Manukian, Voichita Bar-Ad, Bo Lu, Athanassios Argiris, Jennifer M. Johnson

Department of Radiation Oncology Faculty Papers

Head and neck squamous cell carcinoma (HNSCC) is a significant cause of morbidity and mortality worldwide. Current treatment options, even though potentially curative, have many limitations including a high rate of complications. Over the past few years immune checkpoint inhibitors (ICI) targeting cytotoxic lymphocyte antigen-4 (CTLA-4), programmed cell death protein 1 (PD-1), and programmed cell death ligand 1 (PD-L1) have changed treatment paradigms in many malignancies and are currently under investigation in HNSCC as well. Despite improvements in treatment outcomes and the implementation of combined modality approaches long-term survival rates in patients with locally advanced HNSCC remain suboptimal. Accumulating evidence …

Meta-Analysis To Identify And Evaluate Factors Associated With Regulatory Approval Of Orphan Drugs (Od) To Develop An Algorithm For Predicting Regulatory Approval (Success) And To Develop A Standardized Tool To Improve Orphan Drug Portfolio Decision-Making, Milky C. Florent

Seton Hall University Dissertations and Theses (ETDs)

Background and Purpose of the Study: Developed an algorithm (AODI) for predicting probability of regulatory success (PRS) for new orphan drugs after phase II testing has been conductedwith the objective of providing a tool to improve drug portfolio decision-making.Methods: Examined 132 studies from recent publications (2005 onwards). Data on safety, efficacy, operational, market, and company characteristics were obtained from public sources. Meta-analysis and meta-regressions were used to provide an unbiased approach to assess overall predictability and to identify the most important individual predictors.Results: Found that a simple three-factor model (disease prevalence, clinical trial duration and clinical trial …

Evaluating Commonalities Between Different Medically Unexplained Symptoms, Dan Guo, Maria Kleinstäuber, Malcolm Henry Johnson, Frederick Sundram

Psychology Faculty Publications

This commentary presents commonalities in medically unexplained symptoms (MUS) across multiple organ systems, including symptoms, aetiological mechanisms, comorbidity with mental health disorders, symptom burden and impact on quality of life. Further, treatment outcomes and barriers in the clinician–patient relationship, and cross-cultural experiences are highlighted. This discussion is necessary in aiding an improved understanding and management of MUS due to the interconnectedness underlying MUS presentations across the spectrum of medical specialties.

Religious Couples Re-Storying After Infidelity: Using Narrative Therapy Interventions With A Focus On Attachment, Mark Karris , M.A., M.Div., Katarena Arger , M.A

Counseling and Family Therapy Scholarship Review

Attachment-focused narrative interventions used with religious couples of the Abrahamic faiths (Judaism, Christianity and Islam) dealing with the effects of infidelity is discussed in this article. With religious couples, the couple attachment bond is commonly harmed after infidelity. The attachment bond with God can also be affected with one or both partners. Partners who once felt close and connected with God can feel angry and distant because of infidelity. Since the Abrahamic faiths are narrative-based religions, and an attachment bond with God is essential, attachment-focused narrative interventions can help couples re-story their relationship with each other and with God. Attachment-based …

Learning About Roger: A Supervision Case, Joanna Sturhahn Stratton , Ph.D., Randy D. Gallamore , M.A.

Counseling and Family Therapy Scholarship Review

A behavioral health internship provides an unparalleled training experience for a Master’s level clinical trainee. This narrative essay highlights how one behavioral health intern was pushed to the next developmental stage of learning as he encountered a patient with a complex medical condition and a new mental health diagnosis. This article also shares the learner’s perspective on how both the patient and intentional systemic supervision fostered his professional growth.

To Be Known: A Supervisee Experience, Alexa R. Ashworth

Counseling and Family Therapy Scholarship Review

Presented before you are a collective of raw, untamed poetic thoughts from my experiences as a Youth Treatment Counselor. In writing this personal narrative I have been able to let the inner turmoil of my soul soar with peace once more. You will discover how invalidation from supervisors and staff can quickly leave you at a standstill, being left to feel alone. My goal for writing this piece has been to create mental metaphors for others in the field who built up walls as a form of self-preservation, to feel comfort when there is no end. I hope my honesty …

Death And Life By A Thousand Cuts: Lessons Learned From The Deconstructive/Reconstructive Journey, Mark Karris , M.A., M.Div.

Counseling and Family Therapy Scholarship Review

Questioning one’s faith and beliefs about God, church, and their religion can be an excruciating experience. Since we all have an innate need to belong, feel safe, and be loved, we can be reticent to question and doubt our faith due to fear of rejection and isolation from two major figures: God and the church. For many people, it is not easy to separate the two. For some, the fear of losing God’s love, even momentarily, is terrifying. For others, the thought of leaving their beliefs behind may also feel like they have to leave their religious tribe behind, which …

The Mystery And Wonder Of Exploration, H. Luis Vargas , Ph.D.

Counseling and Family Therapy Scholarship Review

The Editor provides an Editorial for the new issue.

Unveiling The Mask:Sexual Trauma's Impact On Academic Achievement, Behavior, And Self-Identity, Teshaunda Hannor-Walker, Sarah Kitchens, Lacey Ricks

National Youth Advocacy & Resilience Conference

Sexual trauma is an unfortunate but a common and often masked experience for many students in America. While sexual trauma in itself is not a mental health disorder, it can become a risk factor for many academic and mental health problems. Trauma-informed schools can play an important role in helping students deal with the aftercare of a traumatic experience.

Engaging Student Nurses In A Professional Association, Nicholas Craig

Student Engagement Posters

Nicholas Craig discusses student engagement at Linfield College with regard to his involement with the Critical Care Nurses' Club.

Bone Marrow Drive: Will Linfield Be The Match?, Ashley Filler

Student Engagement Posters

Ashley Filler discusses student engagement at Linfield College with regard to organizing a bone marrow registration drive.