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Articles 6931 - 6960 of 16116
Full-Text Articles in Medicine and Health Sciences
Understanding The Help-Seeking Behaviors Of Student-Athletes: Effect Of A Multidisciplinary Healthcare Team And The Perception Of Barriers And Facilitators For Seeking Help, Lauren M. Sander
Masters Theses, 2010-2019
This study was aimed at identifying barriers and facilitators that influence help-seeking as well as the effect of implementing an integrated healthcare approach based on current recommendations. A total of 411 student-athletes from 18 intercollegiate teams at a mid-major Division I institution in the mid-Atlantic region completed a 12–item instrument comprised of ten quantitative items and two open-ended questions. The quantitative data was analyzed using SPSS software, and a constant comparative method was used to code responses from the open-ended questions. Findings suggested a prevalence of mental health challenges among student-athletes, especially overwhelming stress, struggles with time management, and anxiety. …
Long-Term Safety Of Secukinumab In Patients With Moderate-To-Severe Plaque Psoriasis, Psoriatic Arthritis, And Ankylosing Spondylitis: Integrated Pooled Clinical Trial And Post-Marketing Surveillance Data., A Deodhar, Philip Mease, I B Mcinnes, X Baraliakos, K Reich, A Blauvelt, C Leonardi, B Porter, A Das Gupta, A Widmer, L Pricop, T Fox
Long-Term Safety Of Secukinumab In Patients With Moderate-To-Severe Plaque Psoriasis, Psoriatic Arthritis, And Ankylosing Spondylitis: Integrated Pooled Clinical Trial And Post-Marketing Surveillance Data., A Deodhar, Philip Mease, I B Mcinnes, X Baraliakos, K Reich, A Blauvelt, C Leonardi, B Porter, A Das Gupta, A Widmer, L Pricop, T Fox
Articles, Abstracts, and Reports
BACKGROUND: Secukinumab, a fully human immunoglobulin G1-kappa monoclonal antibody that directly inhibits interleukin (IL)-17A, has been shown to have robust efficacy in the treatment of moderate-to-severe psoriasis (PsO), psoriatic arthritis (PsA), and ankylosing spondylitis (AS) demonstrating a rapid onset of action and sustained long-term clinical responses with a consistently favorable safety profile in multiple Phase 2 and 3 trials. Here, we report longer-term pooled safety and tolerability data for secukinumab across three indications (up to 5 years of treatment in PsO and PsA; up to 4 years in AS).
METHODS: The integrated clinical trial safety dataset included data pooled from …
Validity And Reliability Of The Exercise Vital Sign Questionnaire In An Ethnically Diverse Group: A Pilot Study, Noberto N. Quiles, Aston K. Mccullough, Lin Piao
Validity And Reliability Of The Exercise Vital Sign Questionnaire In An Ethnically Diverse Group: A Pilot Study, Noberto N. Quiles, Aston K. Mccullough, Lin Piao
Publications and Research
The purpose of this study was to determine the validity and reliability of the Exercise Vital Sign (EVS) questionnaire in an ethnically diverse sample. Participants (N = 39) were asked to wear an accelerometer at the hip for at least 7 days and to complete the EVS at the beginning (T1) and end (T2) of the wear period. The EVS questionnaire validity was determined against accelerometry, and bias was calculated as the mean difference between measures. The sensitivity and specificity of the EVS questionnaire were also evaluated. The reliability of the questionnaire was calculated using intraclass correlation coefficient (ICC) between …
Perspective: Challenges In Use Of Adolescent Anthropometry For Understanding The Burden Of Malnutrition, Alison Tumilowicz, Ty Beal, Lynnette M. Neufeld, Edward A. Frongillo Jr.
Perspective: Challenges In Use Of Adolescent Anthropometry For Understanding The Burden Of Malnutrition, Alison Tumilowicz, Ty Beal, Lynnette M. Neufeld, Edward A. Frongillo Jr.
Faculty Publications
Improving nutritional status during adolescence is an opportunity to improve the lives of this generation and the next. Estimating the burden of malnutrition at a population level is fundamental to targeting interventions and measuring progress over time, and for adolescents, we usually depend on survey data and the 2007 WHO Growth Reference to do so. There is substantial risk of misguided conclusions regarding adolescent prevalence estimates, however, when underlying methodological limitations of the indicators and reference are not adequately considered. We use national prevalence estimates among girls and young women 10-22 y of age from the 2014 State of Food …
Rhabdomyolysis: An Unusual Presenting Symptom Of Hypothyroidism, Kourtney Erickson Do, Grace Berlin Do, Marie S. O’Brien Do
Rhabdomyolysis: An Unusual Presenting Symptom Of Hypothyroidism, Kourtney Erickson Do, Grace Berlin Do, Marie S. O’Brien Do
Department of Medicine
No abstract provided.
Effects Of The Kcnq Channel Opener Ezogabine On Functional Connectivity Of The Ventral Striatum And Clinical Symptoms In Patients With Major Depressive Disorder, Aaron Tan, Sara Costi, Laurel S. Morris, Nicholas T. Van Dam, Marin Kautz, Alexis E. Whitton, Allyson K. Friedman, Katherine A. Collins, Gabriella Ahle, Nisha Chadha, Brian Do, Diego A. Pizzagalli, Dan V. Iosifescu, Eric J. Nestler, Ming-Hu Han, James W. Murrough
Effects Of The Kcnq Channel Opener Ezogabine On Functional Connectivity Of The Ventral Striatum And Clinical Symptoms In Patients With Major Depressive Disorder, Aaron Tan, Sara Costi, Laurel S. Morris, Nicholas T. Van Dam, Marin Kautz, Alexis E. Whitton, Allyson K. Friedman, Katherine A. Collins, Gabriella Ahle, Nisha Chadha, Brian Do, Diego A. Pizzagalli, Dan V. Iosifescu, Eric J. Nestler, Ming-Hu Han, James W. Murrough
Publications and Research
Major depressive disorder (MDD) is a leading cause of disability worldwide, yet current treatment strategies remain limited in their mechanistic diversity. Recent evidence has highlighted a promising novel pharmaceutical target—the KCNQ-type potassium channel—for the treatment of depressive disorders, which may exert a therapeutic effect via functional changes within the brain reward system, including the ventral striatum. The current study assessed the effects of the KCNQ channel opener ezogabine (also known as retigabine) on reward circuitry and clinical symptoms in patients with MDD. Eighteen medication-free individuals with MDD currently in a major depressive episode were enrolled in an open-label study and …
Cardio-Metabolic Disease Risk Factors Among South Asian Labour Migrants To The Middle East: A Scoping Review And Policy Analysis, Shiva Raj Mishra, Saruna Ghimire, Chandni Joshi, Bishal Gyawali, Archana Shrestha, Dinesh Neupane, Sudesh Raj Sharma, Yashashwi Pokharel, Salim S. Virani
Cardio-Metabolic Disease Risk Factors Among South Asian Labour Migrants To The Middle East: A Scoping Review And Policy Analysis, Shiva Raj Mishra, Saruna Ghimire, Chandni Joshi, Bishal Gyawali, Archana Shrestha, Dinesh Neupane, Sudesh Raj Sharma, Yashashwi Pokharel, Salim S. Virani
School of Public Health Faculty Research
This paper aims to explore the burgeoning burden of cardiovascular and metabolic disease (CMD) risk factors among South Asian labor migrants to the Middle East. We conducted a qualitative synthesis of literature using PubMed/Medline and grey literature searches, supplemented by a policy review of policies from the South Asian countries. We found a high burden of cardio-metabolic risk factors among the migrants as well as among the populations in the home and the host countries. For example, two studies reported the prevalence of diabetes mellitus (DM) ranging between 9 and 17% among South Asian migrants. Overweight and obesity were highly …
Children And Their Parents’ Assessment Of Postoperative Surgical Pain: Agree Or Disagree?, Olivia Kaminsky, Michelle Fortier, Brooke N. Jenkins, Robert S. Stevenson, Jeffrey I. Gold, Jeannie Zuk, Brenda Golianu, Sherrie H. Kaplan, Zeev N. Kain
Children And Their Parents’ Assessment Of Postoperative Surgical Pain: Agree Or Disagree?, Olivia Kaminsky, Michelle Fortier, Brooke N. Jenkins, Robert S. Stevenson, Jeffrey I. Gold, Jeannie Zuk, Brenda Golianu, Sherrie H. Kaplan, Zeev N. Kain
Psychology Faculty Articles and Research
Objective
The purpose of this study is to compare postoperative pain scores between children undergoing tonsillectomy and adenoidectomy (T&A) surgery and their parents, identify potential predictors for this disagreement, and determine possible impact on analgesic administration.
Methods
This is a prospective longitudinal study conducted with children undergoing outpatient T&A in 4 major tertiary hospitals and their parents. Children and their parents were enrolled prior to surgery and completed baseline psychological instruments assessing parental anxiety (STAI), parental coping style (MBSS), child temperament (EAS) and parental medication administration attitude questionnaire (MAQ). Postoperatively, parents and children completed at-home pain severity ratings (Faces Pain …
Caspases And Cancer: Connections Through Circular Dichroism Spectroscopy, Sarah M. Hethcox
Caspases And Cancer: Connections Through Circular Dichroism Spectroscopy, Sarah M. Hethcox
Honors College Theses
While excessive cell death inevitably leads to negative effects, the endurance of damaged cells in the presence of death signals can be equally detrimental to health. Apoptosis, or programmed cell death, is a highly regulated process in which cues from within or from outside a cell can trigger an irreversible sequence of signals that carry out cell destruction known as the apoptotic cascade. A group of enzymes called caspases play a vital role in this cascade with some participating as initiators and others acting as effectors of protein cleavage and intracellular breakdown. Although it is normal for the activity of …
Accelerating 3-D Gpu-Based Motion Tracking For Ultrasound Strain Elastography Using Sum-Tables: Analysis And Initial Results., Bo Peng, Shasha Luo, Zhengqiu Xu, Jingfeng Jiang
Accelerating 3-D Gpu-Based Motion Tracking For Ultrasound Strain Elastography Using Sum-Tables: Analysis And Initial Results., Bo Peng, Shasha Luo, Zhengqiu Xu, Jingfeng Jiang
Michigan Tech Publications, Part 1
Now, with the availability of 3-D ultrasound data, a lot of research efforts are being devoted to developing 3-D ultrasound strain elastography (USE) systems. Because 3-D motion tracking, a core component in any 3-D USE system, is computationally intensive, a lot of efforts are under way to accelerate 3-D motion tracking. In the literature, the concept of Sum-Table has been used in a serial computing environment to reduce the burden of computing signal correlation, which is the single most computationally intensive component in 3-D motion tracking. In this study, parallel programming using graphics processing units (GPU) is used in conjunction …
The United States' Relationship With The Insanity Defense Before And After United States V. Hinckley, Natalie R. Peterman
The United States' Relationship With The Insanity Defense Before And After United States V. Hinckley, Natalie R. Peterman
Young Historians Conference
The United States legal system has had a fluctuating relationship with the insanity defense for decades, and the trial of United States v. Hinckley was a critical milestone for this development. Before John Hinckley, Jr. attempted to assassinate President Ronald Reagan in 1981 and the jury of his trial found him not guilty, American society generally supported the insanity defense, but both the public and the government were outraged after Hinckley’s verdict. This outrage and the subsequent political backlash against the insanity defense were motivated by progress in the area of mental illness treatment in the United States. In the …
Unplugged, Krisha Patel '21, Jonathan Gao '21, Jason Li '21
Unplugged, Krisha Patel '21, Jonathan Gao '21, Jason Li '21
Student Leadership Exchange (SLX)
Technology has infiltrated every aspect of our lives. Regardless of financial conditions, most people have a cellphone in their hands at all times—usually a smartphone. TVs are installed in almost every single room in the typical American household and very often powered up with a marathon of a favorite show, playing episode after episode without pause. Kids become obsessed with the latest video game consoles and games, paying exorbitant amounts to be the first of their friends to get their hands on them. Even many parents compulsively check and post updates to a variety of social media sites throughout the …
Mental Health And Drug Use At Imsa, Megan Ptak '21, Melena Braggs '21, Emma Darbro '21, Brooke Bolsinger '21
Mental Health And Drug Use At Imsa, Megan Ptak '21, Melena Braggs '21, Emma Darbro '21, Brooke Bolsinger '21
Student Leadership Exchange (SLX)
Within our campus, there is an evident problem relating to drug use and to underlying mental health issues among students. It is known that the students at IMSA use drugs and alcohol as a coping mechanism for their mental health issues; however, this issue is not discussed on our campus. While many measures have been put into action on campus to prevent drug use, there has been no action to solve the root of the problem, mental health issues. This leads to a continuous problem of drug use within our student body and has a lasting effect on the mental …
The Teen Vaping Crisis, Jayavignesh Ganesan '21, Cynthia Mu '21, Carolina Seoane '21
The Teen Vaping Crisis, Jayavignesh Ganesan '21, Cynthia Mu '21, Carolina Seoane '21
Student Leadership Exchange (SLX)
In today’s society, many teens have the idea that is is cool to vape. This has led to an exponential increase in the number of teenagers addicted to nicotine. This increase is directly caused by nicotine companies, specifically vape companies, presenting their products with appealing and misleading packaging. Indeed, nicotine packages are required to have a warning. However, the warning is usually not taken into consideration, as the warning is not eye-catching. Because of this, we propose that all products containing nicotine, including e-cigarettes, must follow plain packaging regulations. Under plain packaging regulations, companies would be required to have the …
Depiction And Function Of Madness In Elizabethan And Jacobean Literature, Yeiji Seo
Depiction And Function Of Madness In Elizabethan And Jacobean Literature, Yeiji Seo
Young Historians Conference
Since the ancient times of Israel, Greece, and Rome, people with mental illnesses have been regarded as different from others in society. This paper aims to analyze the motives of authors of medical and dramatic texts of Elizabethan and Jacobean literature in regards to mental illness by specifically observing William Shakespeare’s King Lear and Robert Burton’s The Anatomy of Melancholy. This paper also considers the views of other scholars of the field to compose a complete insight on Shakespeare and Burton’s goals in depicting mental illness and finally advocates further research and understanding to positively contribute towards disability reform today.
St. Cloud Hospital Nursing Director Orientation And Mentorship Program, Deb Eisenstadt, Tiffany Omann-Bidinger, Diane Pelant
St. Cloud Hospital Nursing Director Orientation And Mentorship Program, Deb Eisenstadt, Tiffany Omann-Bidinger, Diane Pelant
Nursing Posters
Develop and implement an evidence-based orientation and mentorship program for nursing directors using AONE’s Nursing Executive Competencies along with a structure curriculum.
Importance Of Social Support In Athletics As It Relates To Injury Recovery And Preparedness To Return To Play, Haleigh Gray
Importance Of Social Support In Athletics As It Relates To Injury Recovery And Preparedness To Return To Play, Haleigh Gray
Graduate Theses
Background: Recent studies have evaluated the physical problems as well as the psychological complications that arise from sport injuries. However, little research has been done on techniques to address or mitigate these psychological issues. Objective: The purpose of this study was to investigate how social support was perceived during the injury rehabilitation process and how it influenced return to play preparedness. Setting: National Collegiate Athletic Association (NCAA) Division I mid-major university. Participants: A total of 21 previously injured student-athletes participated in the study. Methods: Through this mixed method study, each student-athlete completed a validated social support survey that evaluated perceived …
Reducing The Second Victim Phenomenon: Healing Our Healers With Caritas Coaching, Shanda N. Whittle
Reducing The Second Victim Phenomenon: Healing Our Healers With Caritas Coaching, Shanda N. Whittle
DNP Qualifying Manuscripts
Background: The second victim phenomenon is one in which nurses and other healthcare providers use dysfunctional mechanisms, such as anger, projection of blame, or drugs and/or alcohol to cope with serious mistakes in the absence of a healthier means for healing (Wu, 2000). This phenomenon can lead to healthcare professional absenteeism, leaving the job or leaving the profession altogether (Burlison, Quillivan, Scott, Johnson, & Hoffman, 2018). Following the release of an editorial by Dr. Wu (2000), organizational peer support programs have been developed to reduce this phenomenon. These types of peer support programs have been found to counter absenteeism and …
"Notjustgirls": Exploring Male-Related Eating Disordered Content Across Social Media Platforms, Jessica Pater, Lauren Reining, Andrew D. Miller, Tammy Toscos Phd, Elizabeth D. Mynatt
"Notjustgirls": Exploring Male-Related Eating Disordered Content Across Social Media Platforms, Jessica Pater, Lauren Reining, Andrew D. Miller, Tammy Toscos Phd, Elizabeth D. Mynatt
Mirro Center Articles
ABSTRACT: Eating disorders (EDs) are a worldwide public health concern that impact approximately 10% of the U.S. population. Our previous research characterized these behaviors across online spaces. These characterizations have used clinical terminology, and their lexical variants, to identify ED content online. However, previous HCI research on EDs (including our own) suffers from a lack of gender and cultural diversity. In this paper, we designed a follow-up study of online ED characterizations, extending our previous methodologies to focus specifically on male/masculine-related content. We highlight the similarities and differences found in the terminology utilized and media archetypes associated with the social …
Ozone Induced Effects On The Mammalian Visual System, Jordan Wetz
Ozone Induced Effects On The Mammalian Visual System, Jordan Wetz
Theses & Dissertations
Research Focus. Millions of people who suffer from retinal disease live in air-polluted environments. The impact of the gaseous air pollutant ozone (O3), a strong oxidant, on the retina is unknown. The aim of the present study is to compare the electroretinographic responses between control (no O3 exposure) and O3 -exposed rats and to better understand the effects of O3 on retinal function.
Materials and Methods. Age-matched adult female rats were separated into two groups (N = 6), 3 control and 3 experimental. The experimental group was exposed to 0.4 ppm O3 for …
Screening Of Crude Microalgal Extracts For Antimicrobial Activity, Patrick Matulich
Screening Of Crude Microalgal Extracts For Antimicrobial Activity, Patrick Matulich
Theses & Dissertations
Microbial biofilm associated infections are a significant threat to patients with medical devices and are partially responsible for the increased resistance seen in nosocomial infections. The biofilm chemical and physical properties restrict access of chemotherapeutic agents. Therefore, there is a need to enhance the antimicrobial effects of current chemotherapeutic agents. Microalgae live in competitive environments that include film-forming, opportunistic pathogens S. maltophilia and C. albicans. Extracts from 5 diverse species of microalgae were screened for antimicrobial enhancing effects against established biofilms with two different extraction solvents, 3:1 hexanes and isopropyl (HIPA) and 2-methyltetrahydrofuran (2-MTHF).
Three species, B. braunii, …
Nursing Leaders’ Ethical Decision-Making About Professional Boundaries And Nurse-Patient Relationships: A Mixed Methods Explanatory Sequential Design, Pamela Scott
Theses & Dissertations
The purpose of this mixed methods explanatory sequential design study was to ascertain nursing leaders’ knowledge and skill in ethical decision-making when evaluating and managing professional nurse-patient relationship boundaries. It was also the purpose of this study to better understand nursing leaders’ perception of moral, cognitive, and organizational factors influencing their ethical decision-making in evaluating and managing professional nurse-patient relationships, with the intent of generating a theory grounded in the views of the participants as a final outcome of the study. The two theories, virtue ethics and self-efficacy comprise the ethicality construct of the conceptual framework explaining the nurse leaders’ …
The Barrier That Deters The Geriatric Population From Receiving Quality Healthcare, Jacquelyn Smith
The Barrier That Deters The Geriatric Population From Receiving Quality Healthcare, Jacquelyn Smith
PCOM Capstone Projects
Purpose : This literature analysis aims to understand the tangible and intangible barriers that impact the growing geriatric population in preventing from receiving quality healthcare
Methods: This literature review allowed for the investigation of the various types of barriers when the American geriatric population tries to access high-quality healthcare. Different types of settings were considered; however, there was a focus on Philadelphia. The analysis allowed for the creation of possible associations and solutions for this issue. Additional articles about the most significant barriers were searched based on an original article by Horton and Johnson (2010).
Results: Cost seems …
Chronic Pain: A Review, Jacob Stein
Chronic Pain: A Review, Jacob Stein
PCOM Capstone Projects
Chronic pain can be a debilitating condition which weighs heavy upon its sufferers and the healthcare system at large. Although such a common condition, chronic pain can be an ambiguous term that incorporates many emotional, psychological, and physical states. Due to epidemiologically relevant psychological and physical conditions between chronic pain patients and substance-use disorder populations, a model relating to the latter population has been suggested. The CReAM (Combined reward anti-reward model) has been used to develop a better understanding of the feed-forward nature of deteriorating pain conditions. Researchers have identified certain anatomical regions that may play a role in the …
Counseling For Patients With Hyperacusis, Mary Maraist
Counseling For Patients With Hyperacusis, Mary Maraist
Communication Sciences and Disorders: Student Scholarship & Creative Works
Hyperacusis is the phenomenon of experiencing moderately loud sounds as overly loud and/or intensely annoying. Hyperacusis can also cause fear or pain in response to sound. There is no one known cause of hyperacusis, and because of the variety of ways it presents itself, the approximate prevalence is difficult to determine. Despite the ambiguity of hyperacusis, the audiologist is an important part of diagnosing and educating clients with hyperacusis. During this project we aimed to discover the challenges individuals with hyperacusis face. These include anxiety, depression and avoidance behavior, and sometimes co-occurring tinnitus and hearing loss. Another aim was to …
Early, Proactive Palliative Care In Hospitalized Patients With Advanced Dementia: A Research Proposal, Tori Viveen
Early, Proactive Palliative Care In Hospitalized Patients With Advanced Dementia: A Research Proposal, Tori Viveen
Yale School of Medicine Physician Associate Program Theses
Dementia is a chronic, progressive and fatal neurodegenerative disease with no curative treatment options. The number of Americans living with dementia is expected to triple between 2018 and 2050. Access to palliative care for patients living with dementia and other chronic diseases like cancer improves quality of life and may even prolong life. However, the optimal timing for a palliative care consult is not yet clear. This study seeks to determine whether early initiation of palliative care in dementia patients admitted to the hospital with acute illness benefits patient clinical outcomes (non-institutionalized days at home, readmissions, location of death) and …
Evidence Based Solutions: Creating Specialty Units, Jacqueline Adams, Msn, Rn, Corln, Ccctm, Megan Bagonis, Rn, Bsn, Michelle Lewandowski, Rn, Bsn, Mha
Evidence Based Solutions: Creating Specialty Units, Jacqueline Adams, Msn, Rn, Corln, Ccctm, Megan Bagonis, Rn, Bsn, Michelle Lewandowski, Rn, Bsn, Mha
Department of Nursing Posters
Purpose
To describe how the development of a specialty Ear, Nose, and Throat (ENT) care unit staffed by experienced ENT nurses positively influences quality outcomes, patient experience, ICU admissions, and readmission and LOS rates in a large, urban, academic medical center.
Social Media's Affect On Self Image And Daily Life, Sarah Falkowski
Social Media's Affect On Self Image And Daily Life, Sarah Falkowski
Senior Honors Projects
In the US alone over 244 million people use social media daily. Social media has become a huge part of the world today, helping people stay connected, share, influence, and interact. Though social media has many constructive aspects, it can affect its users in many negative ways. This research looks deeper into the way people use social media, how it’s content can be damaging, and the emphasis people place on their social media image. The study conducted looks further into how social media’s effects vary between age groups and genders. Results show that females between 16-20 are most negatively affected …
Reflection Of Distinct Nursing Leadership In Argentina, Indonesia And Jamaica., Emely Baez
Reflection Of Distinct Nursing Leadership In Argentina, Indonesia And Jamaica., Emely Baez
Senior Honors Projects
Nurses provide more than 80% of patient care worldwide. Unfortunately, this percentage does not correlate with the number of nurses involved in leadership roles. It’s discouraging to think that the decisions on health care, community, patient care and policy are not being made by those who provide these services and often are the patients’ most passionate advocates. This discrepancy in leadership led me to investigate what factors are at play. Through my observations of nursing practice and leadership in the countries of Jamaica, Argentina and Indonesia, I have specified some of the obstacles or lack of resources in place that …
Acute Promyelocytic Leukemia: A Case Study Correlating Cytogenetic Abnormality With Prognosis, Alyssa Lamond, Theresa Tellier-Castellone
Acute Promyelocytic Leukemia: A Case Study Correlating Cytogenetic Abnormality With Prognosis, Alyssa Lamond, Theresa Tellier-Castellone
Senior Honors Projects
Advancements in medical technology today have positively impacted the diagnosis, treatment, and prognosis of cancers. Particularly acute promyelocytic leukemia (APL) has completely improved from having the poorest prognosis to one of the best. Acute promyelocytic leukemia is a malignant disease of hematopoietic tissue classified by WHO as leukemia with >20% blasts from the myeloid lineage, specifically promyelocytes. Determined in 1976, FAB classified AML subtypes M1-M7, with APL being M3. Specific characteristics classify the subtype of AML, with each resulting from a different genetic abnormality. The focus of APL diagnosis, treatment, and prognosis occurs around the known PML-RARα fusion gene. Flow …