Medicine and Health Sciences Commons^™

Stop-Signal Reaction Time Correlates With A Compensatory Balance Response, Garrett Rydalch, Hayden B. Bell, K. L. Ruddy, David A.E. Bolton

Kinesiology and Health Science Faculty Publications

Background

Response inhibition involves suppressing automatic, but unwanted action, which allows for behavioral flexibility. This capacity could theoretically contribute to fall prevention, especially in the cluttered environments we face daily. Although much has been learned from cognitive psychology regarding response inhibition, it is unclear if such findings translate to the intensified challenge of coordinating balance recovery reactions.

Research question

Is the ability to stop a prepotent response preserved when comparing performance on a standard test of response inhibition versus a reactive balance test where compensatory steps must be occasionally suppressed?

Methods

Twelve young adults completed a stop signal task and …

Grfs And Crfs In Alternative Donor Hematopoietic Cell Transplantation For Pediatric Patients With Acute Leukemia., Rohtesh S. Mehta, Shernan G Holtan, Tao Wang, Michael T. Hemmer, Stephen R. Spellman, Mukta Arora, Daniel R. Couriel, Amin M. Alousi, Joseph Pidala, Hisham Abdel-Azim, Ibrahim Ahmed, Mahmoud Aljurf, Medhat Askar, Jeffery J. Auletta, Vijaya Bhatt, Christopher Bredeson, Saurabh Chhabra, Shahinaz Gadalla, James Gajewski, Robert Peter Gale, Usama Gergis, Peiman Hematti, Gerhard C. Hildebrandt, Yoshihiro Inamoto, Carrie Kitko, Pooja Khandelwal, Margaret L. Macmillan, Navneet Majhail, David I. Marks, Parinda Mehta, Taiga Nishihori, Richard F. Olsson, Attaphol Pawarode, Miguel Angel Diaz, Tim Prestidge, Muna Qayed, Hemalatha Rangarajan, Olle Ringden, Ayman Saad, Bipin N. Savani, Sachiko Seo, Ami Shah, Niketa Shah, Kirk R. Schultz, Melhem Solh, Thomas Spitzer, Jeffrey Szer, Takanori Teshima, Leo F Verdonck, Kirsten M. Williams, Baldeep Wirk, John Wagner, Jean A. Yared, Daniel J. Weisdorf

Department of Medical Oncology Faculty Papers

We report graft-versus-host disease (GVHD)-free relapse-free survival (GRFS) (a composite end point of survival without grade III-IV acute GVHD [aGVHD], systemic therapy-requiring chronic GVHD [cGVHD], or relapse) and cGVHD-free relapse-free survival (CRFS) among pediatric patients with acute leukemia (n = 1613) who underwent transplantation with 1 antigen-mismatched (7/8) bone marrow (BM; n = 172) or umbilical cord blood (UCB; n = 1441). Multivariate analysis was performed using Cox proportional hazards models. To account for multiple testing, P < .01 for the donor/graft variable was considered statistically significant. Clinical characteristics were similar between UCB and 7/8 BM recipients, because most had acute lymphoblastic leukemia (62%), 64% received total body irradiation-based conditioning, and 60% received anti-thymocyte globulin or alemtuzumab. Methotrexate-based GVHD prophylaxis was more common with 7/8 BM (79%) than with UCB (15%), in which mycophenolate mofetil was commonly used. The univariate estimates of GRFS and CRFS were 22% (95% confidence interval [CI], 16-29) and 27% (95% CI, 20-34), respectively, with 7/8 BM and 33% (95% CI, 31-36) and 38% (95% CI, 35-40), respectively, with UCB (P < .001). In multivariate analysis, 7/8 BM vs UCB had similar GRFS (hazard ratio [HR], 1.12; 95% CI, 0.87-1.45; P = .39), CRFS (HR, 1.06; 95% CI, 0.82-1.38; P = .66), overall survival (HR, 1.07; 95% CI, 0.80-1.44; P = .66), and relapse (HR, 1.44; 95% CI, 1.03-2.02; P = .03). However, the 7/8 BM group had a significantly higher risk for grade III-IV aGVHD (HR, 1.70; 95% CI, 1.16-2.48; P = .006) compared with the UCB group. UCB and 7/8 BM groups had similar outcomes, as measured by GRFS and CRFS. However, given the higher risk for grade III-IV aGVHD, UCB might be preferred for patients lacking matched donors. © 2019 American Society of Hematology. All rights reserved.

Localization Of Five Target Proteins In Tachyzoites Of Toxoplasma Gondii, Abigail M. Kaiser

USF Tampa Graduate Theses and Dissertations

Five target genes were selected in Toxoplasma gondii tachyzoites for localization studies. These five genes, detected through proteomics studies, included TgME49_227450, TgME49_223080, TgME49_262390, TgME49_230940, and TgME49_269620. Localization of these five target proteins is a first step to confirm their interaction with TgCrk2 and understand their function and role in TgCrk2 regulation of the tachyzoite cell cycle. Gene models for the targets were analyzed using ToxoDB and ApE analysis tools. Endogenous tagging constructs were created for each target. Transgenic parasites were created. Finally, localization analysis of the target proteins in tachyzoites was completed using immunofluorescent microscopy following. One protein was found …

Improved Coordination Of Care For Picu Patients With Newly Diagnosed Anterior Mediastinal Masses, Laura Mccarthy

Research Days

No abstract provided.

Consensus Guidelines For Postnatal Steroids In Preterm Infants With Developing Bronchopulmonary Dysplasia: A Quality Improvement Initiative, Taylor Hansen

Research Days

No abstract provided.

Decreasing Unplanned Extubations By Taping Technique And Creating A Culture Of Safety, Karishma Rao

Research Days

No abstract provided.

Quality Improvement: Implementing A Diabetic Foot Exam To Improve Quality Of Care For Youth With Diabetes Mellitus, Emily Paprocki

Research Days

No abstract provided.

Resident Great Catches: Recognizing Resident Physicians, Susamita Kesh, Kristin Streiler

Research Days

No abstract provided.

Improving Nicu Referrals To The Missouri Early Intervention Program (First Steps)​, Luke Prest Md

Research Days

No abstract provided.

Optimization Of Surgical Prophylaxis In Penicillin-Allergic Labeled Patients, Katie A. Vandervelde

Research Days

No abstract provided.

A Discrepancy Between The Human Reference Genome (Grch37) And Transcriptome (Refseq) Results In The Incorrect Annotation Of A Clinically-Relevant Sequence Variant In Recql4, Lisa A. Lansdon

Research Days

No abstract provided.

Medication Timeliness In Emergency Department In Pediatric Sickle Cell Disease Population Presenting With Vaso-Occlusive Episode, Derrick L. Goubeaux

Research Days

No abstract provided.

Decreased Antibiotic Use In Well-Appearing Infants Exposed To Maternal Chorioamnionitis, Lauren E. Cummings

Research Days

No abstract provided.

Neuroblastoma In Adolescents And Children Older Than 10 Years: Unusual Clinicopathologic And Biologic Features, Laura Mccarthy

Research Days

No abstract provided.

Mismanagement Of A Cervical Spine Fracture By Multiple Healthcare Providers In A High School Football Player, Alvin Chi

Research Days

No abstract provided.

Improving Handoffs By Incorporating A Standardized Ipass Section Into The Written Handoff Document, Susamita Kesh, Kristin Streiler

Research Days

No abstract provided.

Challenges Of Encountering Infant Delirium On Ecmo, Karishma Rao

Research Days

No abstract provided.

When Parents Take Conflicts To Digital Media, Bryanna Moore

Research Days

No abstract provided.

Gonadotropin Releasing Hormone (Gnrh) Agonist Improves Hyperandrogenism In Adolescent With Novel Insulin Receptor Gene Mutation, Emily Paprocki

Research Days

No abstract provided.

Implementation Of Hpv Vaccination For Child And Adolescent Victims Of Non-Acute Sexual Assault/Abuse, Sara Kilbride

Research Days

No abstract provided.

A Review Of First Year Fellow Endoscopic Skills And Time To Proficiency, Dalya El Tawil, Antoinette Adjowa O. Walker

Research Days

No abstract provided.

A Literature Review On Improving Nurse-Patient Communication Manuscript, Irene Gabbedon

DNP Qualifying Manuscripts

Effective communication happens when the sender of the message sends it, and it is conveyed and understood by the receiver (Gilbert & Hayes, 2009). Medical errors are the third leading cause of death in the United States alone (McMains, 2016). The Joint Commission (TJC) (2019) implemented National Patient Safety Goals (NPSG) in 2002, and improving communication among caregivers has been a goal that has been frequently revised. Due to ineffective communication, life-threatening errors are created among healthcare workers. Nurses play an important role in the communication channel and barriers can be created when there is a lack of health literacy. …

Childhood Obesity: Getting Back To The Basics, Fanny Powell

DNP Qualifying Manuscripts

Childhood obesity is an epidemic that affects the nation. The Centers for Disease Control and Prevention (CDC) (2015) states that over the past thirty years, the prevalence of childhood obesity has more than doubled in younger children and quadrupled in adolescents (CDC, 2015). Although obesity is a multifactorial health issue that is affected by genetics, metabolic factors, socioeconomic factors, and lifestyle choices (Stanford, 2018), a majority of pediatric obesity is as a result of consuming more energy than the body utilizes. There are both immediate and long-term consequences of obesity that negatively affect a child’s health which may carry over …

How To Help People Float, Andrea Andrews

International Journal of Aquatic Research and Education

This manuscript examines how to help more people learn to float because this skill is taking a much more central role in the latest drowning prevention advice in the UK. In 2017 BBC Radio Two show presenter, Simon Mayo, declared that he ‘could not float.’ Many persons in the UK identified with this claim. Despite having been an activity in many traditional swimming lessons floating is not a straight-forward skill for all to master. It requires a high degree of personal trust to have developed in the water. I discuss what learning to float fundamentally entails based on recent publications …

Epidemic Growth Rates And Host Movement Patterns Shape Management Performance For Pathogen Spillover At The Wildlife–Livestock Interface, Kezia R. Manlove, Laura M. Sampson, Benny Borremans, E. Frances Cassirer, Ryan S. Miller, Kim M. Pepin, Thomas E. Besser, Paul C. Cross

United States Department of Agriculture Wildlife Services: Staff Publications

Managing pathogen spillover at the wildlife–livestock interface is a key step towards improving global animal health, food security and wildlife conservation. However, predicting the effectiveness of management actions across host–pathogen systems with different life histories is an on-going challenge since data on intervention effectiveness are expensive to collect and results are system-specific.We developed a simulation model to explore how the efficacies of different management strategies vary according to host movement patterns and epidemic growth rates. The model suggested that fast-growing, fast-moving epidemics like avian influenza were best-managed with actions like biosecurity or containment, which limited and localized overall spillover risk. …

What's Happening: May 13, 2019, Maine Medical Center

What's Happening

No abstract provided.

It Is In The Cards: An Analysis Of Greeting Card Selection Through Identity And Personality, Emily Topilow

Honors Projects

In this exploratory study, personal and social identity were analyzed for their effect on how consumers choose greeting cards. Factors, including personality, relationships, and identity will be qualitatively analyzed to understand people’s buying habits. Certain factors, including gender, personality, relationships, type of card, and frequency of receiving and giving cards, will be qualitatively analyzed for frequency. The two theories analyzed were the Social Identity Theory (SIT) and the Identity Theory (IT).

525 college-aged students were surveyed to examine their purchasing habits of greeting cards. The results showed that the identity of the card giver and the identity of the card …

Week Of May 13, 2019, New York Medical College

InTouch

• Department of Family and Community Medicine Hosts Seventh Annual Research Day
• NYMC Students Published in Academic Journals

Health Care In The Caribbean: A Comparative Analysis Between Cuba And Puerto Rico, Matheus Moreira Sanches Peraci

Honors Projects

The paper at hand focuses on comparing the differences of the Cuban and Puerto Rican health care (HC) system and conditions. As this is a comparative research analysis, this was done by reviewing many different reliable sources and compiling the relevant information from Cuba and Puerto Rico. The factors that were taken into account are: (a) Political and Health Care Systems, (b) Natural and Artificial Disaster and (c) Country’s Demographics and Health Statistics.

Improved Coordination Of Care For Picu Patients With Newly Diagnosed Anterior Mediastinal Masses, Laura Mccarthy

Presentations

This presentation describes a quality improvement project to develop a multi-disciplinary standardized approach for prompt surgical intervention to establish a diagnosis of anterior mediastinal mass. The aim was to decrease the time from presentation to surgical diagnostic procedure totreatment.