Medicine and Health Sciences Commons^™

Development And Validation Of The Workplace Mental Illness Stigma Scale (W-Miss), Nicholas Anthony Smith

Dissertations and Theses

Although 1 in 5 Americans will experience a mental illness at some point, each year people with mental illnesses continue to face high levels of stigmatization and discrimination at work. Recognizing this, many organizational researchers and practitioners have sought to improve workplaces for employees with mental illness through a variety of organizational interventions. Unfortunately, few interventions are thoroughly evaluated. One barrier to evaluating such interventions is the lack of a theoretically meaningful measure of workplace mental illness stigma. In this dissertation, I proposed to develop and evaluate such a measure (the W-MISS) based on Jones, Farina, Hastorf, Markus, Miller, and …

Generation Of Oligodendrocyte Progenitor Cells From Mouse Bone Marrow Cells., Yuan Zhang, Xin-Yu Lu, Giacomo Casella, Jing Tian, Ze-Qing Ye, Ting Yang, Juan-Juan Han, Ling-Yu Jia, A. M. Rostami, Xing Li

Department of Neurology Faculty Papers

Oligodendrocyte progenitor cells (OPCs) are a subtype of glial cells responsible for myelin regeneration. Oligodendrocytes (OLGs) originate from OPCs and are the myelinating cells in the central nervous system (CNS). OLGs play an important role in the context of lesions in which myelin loss occurs. Even though many protocols for isolating OPCs have been published, their cellular yield remains a limit for clinical application. The protocol proposed here is novel and has practical value; in fact, OPCs can be generated from a source of autologous cells without gene manipulation. Our method represents a rapid, and high-efficiency differentiation protocol for generating …

Price Variance For Malaria Prophylaxis Among Northeastern Us Pharmacies, Marcelo Gareca Md, Mark Knouse Md

Department of Medicine

No abstract provided.

Using Entrustable Professional Activities To Improve Pediatric Residency Evaluations, Kelli N. Harajda Md, Kris Rooney Md

Department of Pediatrics

No abstract provided.

Impactful Care: Addressing Social Determinants Of Health Across Health Systems, Nicole Lisa Friedman

Dissertations and Theses

There is emerging evidence that addressing health-related social needs through enhanced clinical-community linkages can improve health outcomes and reduce costs. Unmet health-related social needs, such as food insecurity, inadequate or unstable housing, and lack of access to transportation may increase the risk of developing chronic conditions, reduce an individual's ability to manage these conditions, increase health care costs, and lead to avoidable health care utilization. In response, work on social needs is happening across large health systems in the United States, but the pace of progress is slow and accountability is diffuse.

The goal of this applied research project is …

Extreme Site Fidelity As An Optimal Strategy In An Unpredictable And Homogeneous Environment, Brian D. Gerber, Mevin B. Hooten, Christopher P. Peck, Mindy B. Rice, James H. Gammonley, Anthony D. Apa, Amy J. Davis

United States Department of Agriculture Wildlife Services: Staff Publications

1. Animal site fidelity structures space use, population demography and ultimately gene flow. Understanding the adaptive selection for site fidelity patterns provides a mechanistic understanding to both spatial and population processes. This can be achieved by linking space use with environmental variability (spatial and temporal) and demographic parameters. However, rarely is the environmental context that drives the selection for site fidelity behaviour fully considered.

2. We use ecological theory to understand whether the spatial and temporal variability in breeding site quality can explain the site fidelity behaviour and demographic patterns of Gunnison sage‐grouse (Centrocercus minimus). We examined female site fidelity …

Extreme Events Reveal An Alimentary Limit On Sustained Maximal Human Energy Expenditure, Caitlin Thurber, Lara R. Dugas, Cara Ocobock, Bryce Carlson, John R. Speakman, Herman Pontzer

Publications and Research

The limits on maximum sustained energy expenditure are unclear but are of interest because they constrain reproduction, thermoregulation, and physical activity. Here, we show that sustained expenditure in humans, measured as maximum sustained metabolic scope (SusMS), is a function of event duration. We compiled measurements of total energy expenditure (TEE) and basal metabolic rate (BMR) from human endurance events and added new data from adults running ~250 km/week for 20 weeks in a transcontinental race. For events lasting 0.5 to 250+ days, SusMS decreases curvilinearly with event duration, plateauing below 3× BMR. This relationship differs from that of shorter events …

The Benefits Of Lasix For Exercise-Induced Pulmonary Hemorrhage: 50 Years Of Science And Clinical Experience, Kimberly Brewer, Clara Fenger, Thomas Tobin

Maxwell H. Gluck Equine Research Center Faculty Publications

No abstract provided.

School Of Nursing News, Georgia Southern University

Nursing: News & Publications (2013-2023)

• Georgia Southern University's School of Nursing's Master of Science in Nursing (MSN) with a concentration in chronic care management was recently named the most affordable online nursing master's program by the SR Education Group.

A Community Pharmacy Elective Course Utilizing A Service Development Project To Foster Innovation And Creative Thinking, Danielle Mayer, Pharmd, Bcacp

College of Pharmacy Posters

Course Description

Innovations in Community Pharmacy Practice is a 2-credit hour course offered to pharmacy students in the spring of the third professional year.

Teaching methods

• Group discussions
• Case study activity
• Self-reflection
• Group project

The focus of this course is the evolving role of the community pharmacist in delivering direct patient care services. Students learn the basics of creating a business plan and utilize these principles to create their own business plan for a new or enhanced service that could be implemented at a community pharmacy site. This is a hands-on, project- based course, designed to foster innovation, entrepreneurship, and …

Client Centered Simulation: Practicing Interprofessional Teamwork With Standardized Patients, E. Adel Herge, Otd, Otr/L, Faota, Sarah Libros, Ba, Courtney Newsome, Ba, Richard Hass, Phd, Caitlin Cadematori, Ots, Abegale Nelson, Bs, Neal Geosits, Ba

Department of Occupational Therapy Posters and Presentations

Background

Interprofessional education (IPE) prepares students to work in collaborative teams (Burin et al., 2009). Educators use a variety of methods to develop and enhance teamwork skills (Fox et al., 2018).

Standardized patient (SP) simulations allow students to practice skills in safe environments (Herge et al., 2013) and respond to situations as they would under natural conditions (McGaghie, 1999). As an active learning experience, SP simulations help students break through the “illusion of understanding” (Syinicki & McKeachie, 2001 p. 190).

Kirkpatrick posits a hierarchy of changes as a result of training/education (Kirkpatric, 1979). At the highest level is transfer of …

Alterations In Cortical Activation Among Individuals With Chronic Ankle Instability During Single-Limb Postural Control, Adam B. Rosen, Jennifer M. Yentes, Melanie L. Mcgrath, Arthur C. Maerlender, Sara A. Myers, Mukul Mukherjee

Center for Brain, Biology, and Behavior: Faculty Publications

Context: Chronic ankle instability (CAI) is characterized by repetitive ankle sprains and perceived instability. Whereas the underlying cause of CAI is disputed, alterations in cortical motor functioning may contribute to the perceived dysfunction.

Objective: To assess differences in cortical activity during single-limb stance among control, coper, and CAI groups.

Design: Cross-sectional study.

Setting: Biomechanics laboratory.

Patients or Other Participants: A total of 31 individuals (10 men, 21 women; age = 22.3 ± 2.4 years, height = 169.6 ± 9.7 cm, mass = 70.6 ± 11.6 kg), who were classified into control (n = 13), coper (n = 7), and CAI …

Electronic Notebooks To Facilitate Student Learning Within And Beyond The Classroom, Mary Muhlenhaupt, Otd, Otr/L, Faota, Mary Ann Wagner-Graham, Phd, Gary E. Kaplan, Mslis, Ahip

Thomas Jefferson University Faculty Days

Introduction

Electronic Research Notebooks (ERN), also called Electronic Lab Notebooks, are becoming standard in many industries and academic labs where documentation, reproducibility, online access, and collaboration tools are important (1,2, 3). Jefferson launched cloud-based LabArchives in 2018 as its ERN. The product includes a Classroom Edition for use with students. It offers instructors options to embed course readings, documents, assignments, images, videos, audio files and links to other online resources. Students can type and save notes in their electronic notebook, complete and submit assignments, draw and annotate images and illustrations. Instructors can update the students’ notebooks anytime, grade assignments, comment …

Engaging Students To Improve Research Competencies, Sam Bardarik, Mlis, Paul Hunter, Dmd, Mlis, Gary Kaplan, Mslis, Ahip

Thomas Jefferson University Faculty Days

By increasingly incorporating a variety of student engagement methods into instruction sessions, librarians will be able to build on basic skills (remembering, understanding, applying) and develop students’ higher order learning skills (analysis, evaluation, and creation). For example, a skill librarians have recently introduced is critical appraisal of the literature, one component that ensures students effectively incorporate evidence-based practice into patient care. Librarians also aim to assess student learning and make appropriate iterative modifications to ensure these methods effectively set up students for success. Together, librarians and faculty are laying the groundwork to facilitate lifelong learning in Jefferson students.

Jeffmd’S Wellness Thread: Lessons Learned, Nethra Ankam, Md

Thomas Jefferson University Faculty Days

Background

“Nearly half of U.S. medical students experience symptoms of burnout such as feeling emotionally exhausted, detached from patients, and that their efforts do not make a difference” –Dyrbye & Shanafelt 2011

Systems solutions must be pursued to promote wellness and reduce burnout. Per Shanafelt & Noseworthy 2017, when groups/organizations operate under the assumption that wellness and burnout are the sole responsibility of the individual, efforts to improve wellness are looked upon with skepticism by physicians and organizational factors are neglected. Individuals may pursue strategies to mitigate burnout that work for the individual, but not for the group/organization. Systems strategies …

Wittman, Dorothy M., 1917-2010 (Sc 3438), Manuscripts & Folklife Archives

Manuscript Collection Finding Aids

Finding aid and scans (Click on "Additional Files" below) for Manuscripts Small Collection 3438. Materials related to 2nd Lieutenant Dorothy M. Wittman’s service as a U.S. Army nurse with the 32nd Station Hospital during World War II. Includes a letter to her parents in Canal Fulton, Ohio, from Camp Breckinridge, Kentucky describing a review of the 98th Infantry Division; photographs of her and fellow nurses; a nurses roster; meal tickets; and a whimsical “Dishonorable Discharge” from the Army. Also includes a medical history of the 32nd Station Hospital Unit written by Chief Nurse Helen W. Brammer.

Highlights From The American Heart Association's Epi|Lifestyle 2019 Scientific Sessions, Alvaro Alonso, Madison D. Anderson, Michael P. Bancks, Sherry Ann Brown, Melissa C. Caughey, Alex R. Chang, Erin Delker, Kathryn Foti, Véronique Gingras, Michael G. Nanna, Alexander C. Razavi, Jewel Scott Phd, Rn, Fnp-C, Elizabeth Selvin, Catherine Tcheandjieu, Alvin G. Thomas, Ruth Alma N. Turkson-Ocran, Allison Webel, Deborah R. Young, Bailey M. Debarmore

Faculty Publications

No abstract provided.

Highlights From The American Heart Association's Epi|Lifestyle 2019 Scientific Sessions, Alvaro Alonso, Madison D. Anderson, Michael P. Bancks, Sherry Ann Brown, Melissa C. Caughey, Alex R. Chang, Erin Delker, Kathryn Foti, Véronique Gingras, Michael G. Nanna, Alexander C. Razavi, Jewel Scott Phd, Rn, Fnp-C, Elizabeth Selvin, Catherine Tcheandjieu, Alvin G. Thomas, Ruth Alma N. Turkson-Ocran, Allison Webel, Deborah R. Young, Bailey M. Debarmore

Faculty Publications

No abstract provided.

A Mendelian Randomization Study Of Coronary Artery Disease And Three Amino Acids: Alanine, Glycine, And Glutamine, Allan Uribe

Dissertations and Theses

Cardiovascular disease is the leading cause of death worldwide. Coronary Artery Disease (CAD) accounts for the majority of those deaths. Observational studies have identified risk factors that have been helpful in lowering the death rate, including hypertension, high cholesterol, diabetes, smoking, physical inactivity and poor diet. The effects of these risk factors on CAD remain unclear. To clarify the effect of three amino acids, alanine, glutamine, and glycine on CAD I applied a two sample Mendelian randomization analysis to extensively genotyped observational data. In a sample with up to 184,000 individuals and approximately 60,000 controls, SNPs that reached genome wide …

Using Big Data Analytics To Improve Hiv Medical Care Utilisation In South Carolina: A Study Protocol, Bankole Olatosi, Jiajia Zhang, Sharon Weissman, Jianjun Hu, Mohammad Rifat Haider, Xiaoming Li

Faculty Publications

Introduction Linkage and retention in HIV medical care remains problematic in the USA. Extensive health utilisation data collection through electronic health records (EHR) and claims data represent new opportunities for scientific discovery. Big data science (BDS) is a powerful tool for investigating HIV care utilisation patterns. The South Carolina (SC) office of Revenue and Fiscal Affairs (RFA) data warehouse captures individual-level longitudinal health utilisation data for persons living with HIV (PLWH). The data warehouse includes EHR, claims and data from private institutions, housing, prisons, mental health, Medicare, Medicaid, State Health Plan and the department of health and human services. The …

Ileocecal Valve Tuberculosis In Setting Of Terminal Ileitis In Patient With Septic Shock And Pneumonia, Lisa Kurth Md, Daniel Latta Md, Giovanni Bonomo Md, John S. Park Md

Department of Surgery

No abstract provided.

Peripheral Synucleinopathy In A Dj1 Patient With Parkinson Disease, Cataracts, And Hearing Loss, Derek P. Narendra, Risa Isonaka, Diana Nguyen, Alice B. Schindler, Angela D. Kokkinis, Debra Ehrlich, Tanya M. Bardakjian, David S. Goldstein, Tsao-Wei Liang, Pedro Gonzalez-Alegre

Department of Neurology Faculty Papers

No abstract provided.

Using Marginal Structural Models To Control For Time-Dependent Confounding And Detect Effect Modification In A Randomized Control Trial With A Time-Varying Exposure, Non-Adherence And Missing Data, Elizabeth A. Lancet

Dissertations and Theses

Background: Unlike traditional regression used in the Intention to Treat (ITT) approach, Marginal Structural Models (MSM) can account for joint effects of baseline and subsequent treatments as well as the presence of time-dependent confounding influenced by prior treatment and selection bias due to censoring. In addition, MSMs have been theorized to be able to assist investigators in determining the overall benefit of a drug in the total population as they are able to provide a summary effect size across all strata of an effect modifier which cannot be done via tradition regression techniques. The overall goal of this dissertation is …

Comorbidities And Medication Adherence Among Older Individuals Living With Hiv In The United States, Amanda M. Kong

Dissertations and Theses

The number of people living with HIV (PLWH) ≥65 years old is increasing in the United States (US) as PLWH live longer. In 2015, there were nearly 1 million people living with diagnosed HIV in the US and under 10% were age ≥65. By 2035, the proportion of PLWH in this age group is projected to be 27%. Like the general population of elderly individuals, as they age, PLWH face age-related comorbidities, many of which require routine medical care and daily medications, in addition to daily antiretroviral therapy (ART) for treatment of HIV. Previous research has found that PLWH develop …

Use Of And Access To Abortion Services Among Asian And Immigrant Populations In The United States, Sheila Desai

Dissertations and Theses

Background: Abortion is common in the United States (U.S.) and a critical component of comprehensive reproductive health care. Yet, little research has documented patterns of abortion use among Asian populations or potential barriers to abortion care among immigrants in the U.S., two rapidly growing but understudied populations. In response, this dissertation aims to examine use of and access to abortion services among individuals obtaining abortions in the U.S., focusing specifically on Asians in New York City (NYC), immigrants in the U.S., and individuals living in high immigrant concentration neighborhoods in the U.S.

Methods: Using vital statistics data from …

The Association Of Higher Carbon Dioxide Levels And Teachers’ Perceived Air Quality And Well Being In New York City Elementary Schools, Leon Levine

Dissertations and Theses

Introduction:

Several recent studies have investigated the direct effects of carbon dioxide (CO₂) at concentrations typically found in office buildings on occupant cognitive functioning. These studies have reported a significant association between (impaired) decision making ability and exposure to increased levels of CO₂ (600 ppm versus 1500 ppm). The findings have serious implications in a classroom setting since the objective of schools is to provide an optimal environment for learning. If CO₂ levels in schools are elevated, the teachers’ health and the students’ learning environment will be compromised. Higher CO₂ levels could impact teachers’ and …

Our Criminal Justice System Should Not Be Our Mental Health System (But It Is), Donald Roth

Faculty Work Comprehensive List

"Our criminal justice system is like the silt layer at the bottom of the ocean. If a problem isn’t taken care of higher up in society, it will eventually find its way down to the criminal justice system."

Posting about the need for criminal law reform from In All Things - an online journal for critical reflection on faith, culture, art, and every ordinary-yet-graced square inch of God’s creation.

https://inallthings.org/our-criminal-justice-system-should-not-be-our-mental-health-system-but-it-is/

Early Rapid Decline In Kidney Function In Medically Managed Patients With Atherosclerotic Renal Artery Stenosis., Emily L Cooper, Yanmei Xie, Hanh Nguyen, Pamela S Brewster, Haden Sholl, Megan Sharrett, Kaili Ren, Tian Chen, Katherine Tuttle, Steven T Haller, Kenneth Jamerson, Timothy P Murphy, Ralph B D'Agostino, Joseph M Massaro, William Henrich, Christopher J Cooper, Donald E Cutlip, Lance D Dworkin, Joseph I Shapiro

Articles, Abstracts, and Reports

Background Early rapid declines of kidney function may occur in patients with atherosclerotic renal artery stenosis with institution of medical therapy. The causes and consequences are not well understood. Methods and Results Patients enrolled in the medical therapy-only arm of the CORAL (Cardiovascular Outcomes With Renal Artery Lesions) study were assessed for a rapid decline (RD) in estimated glomerular filtration rate (eGFR), defined as a ≥30% decrease from baseline to either 3 months, 6 months, or both. In the medical therapy-only cohort, eGFR was available in 359 subjects at all time points, the subjects were followed for a median of …

Roles Of Gm-Csf In The Pathogenesis Of Autoimmune Diseases: An Update., Noushin Lotfi, Rodolfo Thome, Nahid Rezaei, Guang-Xian Zhang, Abbas Rezaei, A. M. Rostami, Nafiseh Esmaeil

Department of Neurology Faculty Papers

Granulocyte-macrophage colony-stimulating factor (GM-CSF) was first described as a growth factor that induces the differentiation and proliferation of myeloid progenitors in the bone marrow. GM-CSF also has an important cytokine effect in chronic inflammatory diseases by stimulating the activation and migration of myeloid cells to inflammation sites, promoting survival of target cells and stimulating the renewal of effector granulocytes and macrophages. Because of these pro-cellular effects, an imbalance in GM-CSF production/signaling may lead to harmful inflammatory conditions. In this context, GM-CSF has a pathogenic role in autoimmune diseases that are dependent on cellular immune responses such as multiple sclerosis (MS) …

The Xfp (17-Bm) Beamline For X-Ray Footprinting At Nsls-Ii, Awuri Asuru, Erik R. Farquhar, Michael Sullivan, Donald Abel, John Toomey, Mark R. Chance, Jen Bohon

Faculty Scholarship

Hydroxyl-radical mediated synchrotron X-ray footprinting (XF) is a powerful solution-state technique in structural biology for the study of macromolecular structure and dynamics of proteins and nucleic acids, with several synchrotron resources available to serve the XF community worldwide. The XFP (Biological X-ray Footprinting) beamline at the NSLS-II was constructed on a three-pole wiggler source at 17-BM to serve as the premier beamline for performing this technique, providing an unparalleled combination of high flux density broadband beam, flexibility in beam morphology, and sample handling capabilities specifically designed for XF experiments. The details of beamline design, beam measurements, and science commissioning results …