Medicine and Health Sciences Commons^™

Week Of July 22, 2019, New York Medical College

InTouch

• Inaugural Clinical Laboratory Sciences Class Arrives at NYMC
• Medical Students Receive POCUS Training
• NYMC Researchers Aim to Transform Treatment of Babesiosis
• The Latest Issue of Chironian is Now Online

"Every Day I Think About Your Messages": Assessing Text Messaging Engagement Among Latino Smokers In A Mobile Cessation Program., Francisco Cartujano-Barrera, Evelyn Arana-Chicas, Mariana Ramírez-Mantilla, Jaime Perales, Lisa Sanderson Cox, Edward F. Ellerbeck, Delwyn Catley, Ana Paula Cupertino

Manuscripts, Articles, Book Chapters and Other Papers

Introduction: Mobile health interventions are a promising mode to address tobacco-related disparities among Latinos, the largest minority group and the highest users of text messaging technology. The purpose of this pilot study was to assess engagement in a smoking cessation intervention delivered via text message (Kick Buts) among Latino smokers.

Methods: We relied on a community-based recruitment strategy to enroll 20 Latino smokers in Kick Buts. Outcome measures included biochemically verified abstinence at 12 weeks, participant text messaging interactivity with the program, and satisfaction.

Results: Participants' mean age was 40.7 years old (SD=14.6). Most of the participants were male (70%), …

Endovascular Management Of Free Floating Common Carotid Thrombi, Kevin Carr Md, Zachary Thwing Md, Ravishankar Shivashankar Md, Yafell Serulle Md

Radiology

• The incidence of symptomatic free-floating thrombi of the common carotid artery (CCA) is as low as 0.24-5% incidence in stroke victims. Patients are predisposed to a prothrombotic state
• Historical management options were limited to surgical and medical options both with individual attendant risk profiles
• Large thrombi can present with various degrees of clinical severity
• The endovascular approach is a viable tool to manage these patients

Community Stroke Practice Experience With Small Vessel Thrombectomy, Kevin Carr Md, Zachary Thwing Md, David Pasquale Md, Ravishankar Shivashankar Md, Yafell Serulle Md

Radiology

• Emergent endovascular revascularization is currently mainstay for patients presenting with emergent Large Vessel Occlusion (LVO) of the intracranial circulation
• Stroke symptoms affecting smaller vessels can carry significant morbidity
• Newer technologies and greater experience with the endovascular approach make treatment for small vessel occlusions increasingly more manageable
• This is more relevant in patients presenting outside the tPA window with poor collateral circulation
• We present our technical institutional experience with the endovascular management of acute occlusions of the M2-M3 MCA, A1-A2 ACA and P1-P2 PCA territories.

‘Dancing At The Vatican,’ About Huntington’S Families' Remarkable Papal Audience, Premieres July 27, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.

Wearable Sensors For Monitoring The Physiological And Biochemical Profile Of The Athlete, Dhruv R. Seshadri, James R. Rowbottom, Celeste Marie Alfes, Christian A. Zorman, Colin K. Drummond

Faculty Scholarship

Athletes are continually seeking new technologies and therapies to gain a competitive edge to maximize their health and performance. Athletes have gravitated toward the use of wearable sensors to monitor their training and recovery. Wearable technologies currently utilized by sports teams monitor both the internal and external workload of athletes. However, there remains an unmet medical need by the sports community to gain further insight into the internal workload of the athlete to tailor recovery protocols to each athlete. The ability to monitor biomarkers from saliva or sweat in a noninvasive and continuous manner remain the next technological gap for …

Medical School Watercooler Newsletter - July 21, 2019, Lindsey Lyle

Watercooler Newsletter

This is the July 21, 2019 edition of the Frederick P. Whiddon College of Medicine's Newsletter - Watercooler.

Contents Include:

46th annual Summer Research Day features medical student presentations

Med School Café video online: "Uterine Artery Embolization: A Treatment Option for Symptomatic Fibroids"

University of South Alabama medical students apply their skills an ocean away

Teng joins pathology department at USA College of Medicine

An Interpretative Phenomenological Analysis Investigating Uk Female Experiences Of Psychosocial Adjustment Following Bariatric Surgery, Mark J. Maxwell

The Qualitative Report

The psychosocial impact of bariatric surgery has not been studied as diligently as the physical impact, particularly within the first 6 months following surgery. The aim of the present study was to explore psychosocial adjustment in UK bariatric candidates within this time-scale. Six female participants were purposively recruited to complete a semi-structured interview, and Interpretative Phenomenological Analysis was used to analyse their experiences. Four super-ordinate themes emerged from the interview data which were: (1) "It was me but it wasn’t me": pre-surgery identity, (2) "I don’t see myself as this fat blob of a person anymore": transforming identity, (3) "No …

An Evaluation Of The Registration And Use Prospects For Four Candidate Toxicants For Controlling Invasive Mongooses (Herpestes Javanicus Auropunctatus), Emily W. Ruell, Chris N. Niebuhr, Robert T. Sugihara, Shane R. Siers

United States Department of Agriculture Wildlife Services: Staff Publications

The eradication or control of invasive small Indian mongooses from islands likely requires toxic baiting when removal by trapping proves insufficient. The one toxic bait currently registered for mongooses in the United States has relatively low palatability and efficacy for mongooses. Developing and registering a new pesticide can be very expensive, while funding for developing toxicants for mongooses is limited. Once registered, use of a toxic bait may be hindered by other factors, such as public opposition to an inhumane toxicant, poorer efficacy than expected, or if the toxic bait is difficult for applicators to apply or store. Therefore, we …

The Bone Extracellular Matrix As An Ideal Milieu For Cancer Cell Metastases., Alexus D. Kolb, Karen M. Bussard

Department of Cancer Biology Faculty Papers

Bone is a preferential site for cancer metastases, including multiple myeloma, prostate, and breast cancers.The composition of bone, especially the extracellular matrix (ECM), make it an attractive site for cancer cell colonization and survival. The bone ECM is composed of living cells embedded within a matrix composed of both organic and inorganic components. Among the organic components, type I collagen provides the tensile strength of bone. Inorganic components, including hydroxyapatite crystals, are an integral component of bone and provide bone with its rigidity. Under normal circumstances, two of the main cell types in bone, the osteoblasts and osteoclasts, help to …

Applying Contemporary Management Principles To Implementing And Evaluating Value-Added Pharmacist Services., Shane P. Desselle, Leticia R Moczygemba, Antoinette B Coe, Karl Hess, David P Zgarrick

Faculty Publications & Research of the TUC College of Pharmacy

Value-added pharmacy services encompass traditional and emerging services provided by pharmacists to individual and entire populations of persons increasingly under the auspices of a public health mandate. The success of value-added pharmacy services is enhanced when they are carried out and assessed using appropriate theory-based paradigms. Many of the more important management theories for pharmacy services consider the "servicescape" of these services recognizing the uniqueness of each patient and service encounter that vary based upon health needs and myriad other factors. In addition, implementation science principles help ensure the financial viability and sustainability of these services. This commentary reviews some …

Social Cognitive Theories And Electronic Health Design: Scoping Review, Patricia Grace-Farfaglia

Nutrition Sciences Faculty Publications

Background: There are several social cognitive theories (SCTs) and models that support platform design in electronic health (eHealth) promotion trials. The rationale for this scoping review was to determine how social design features (informational aid, expressive support, gaming, and tailored content) are used to promote self-efficacy, engagement, knowledge, and behavior change. Objective: This study aimed to review a broad spectrum of digital health interventions in the literature seeking trials that use SCTs for the design of eHealth applications. Methods: The author conducted a systematic scoping review of 161 Web-based health interventions from published randomized clinical trials using 1 or more …

Procedural Memory Following Moderate-Severe Traumatic Brain Injury: Group Performance And Individual Differences On The Rotary Pursuit Task, Arianna Rigon, Nathaniel B. Klooster, Samantha Crooks, Melissa C. Duff

Communication Disorders Faculty Research

The impact of traumatic brain injury (TBI) on procedural memory has received significantly less attention than declarative memory. Although to date studies on procedural memory have yielded mixed findings, many rehabilitation protocols (e.g., errorless learning) rely on the procedural memory system, and assume that it is relatively intact. The aim of the current study was to determine whether individuals with TBI are impaired on a task of procedural memory as a group, and to examine the presence of individual differences in performance. We administered to a sample of 36 individuals with moderate-severe TBI and 40 healthy comparisons (HCs) the rotary …

Beyond The 3rs: Expanding The Use Of Human-Relevant Replacement Methods In Biomedical Research, Kathrin Herrmann, Francesca Pistollato, Martin L. Stephens

Biomedical Research and Alternative Methods Collection

This year marks the 60th anniversary of Russell and Burch’s pioneering book, The Principles of Humane Experimental Technique. Their 3Rs framework has helped to inspire humane and scientific progress in experimental technique. However, it is time to update its strategic application. The 21st century has already seen the development of promising, high-tech non-animal models, such as organs-on-a-chip and computational approaches that, in our view, will replace animals as the default option in biomedical experimentation. How fast this transition will take place will depend on the pace at which these new models are optimized to reflect the biology of humans, rather …

Black Women’S Wellbeing: The Intersections Of Race, Immigrant Status, And Mental Health Among African Diasporan Women In Houston, Texas, Sianneh Vesslee

African American and Africana Studies Summer Fellows

My central research question is: how has white supremacy impacted African Diaspora women’s mental health, access to mental healthcare, and identities as mental health patients in the United States as discernible in advertisements and state policies for psychological wellness? More specifically, I will investigate whether and/or how white supremacy shapes the ways in which advertising and state policies for mental healthcare address the particular needs of black women who immigrate to Houston, Texas from Lagos, Nigeria and Coahuila, Mexico. I choose those geographies because Houston is a U.S. city with one of the highest populations of black immigrants from Nigeria …

Inadequate Data Limit The Analysis Of Health Disparities And Causes: A Call For Research On Youth Interpersonal Violence, Maria Isabel Roldós, Tilda Farhat

Publications and Research

Interpersonal violence among racial and ethnic minority youth is of great concern in health disparity research. Child maltreatment (CM), adolescent dating abuse (ADA), sexual abuse, and polyvictimization are key forms of interpersonal violence that require surveillance and national epidemiological data. However, national data systems and published evidence do not depict this health burden for all racial and ethnic populations. Prevalence and incidence rates for American Indians, Eskimo, and Asian youth are absent from most estimates. This commentary provides a brief overview of the gaps in the literature and offers suggestions for addressing these gaps.

Main And Regional Campus Assessments Of Applicants To A Rural Physician Leadership Program: A Generalizability Analysis, Terry D. Stratton, Clarence Kreiter, Carol L. Elam

Behavioral Science Faculty Publications

While the selection of qualified applicants often relies, in part, on scores generated from a medical school pre-admission interview (MSPI), the growth of regional medical campuses (RMCs) – many with specialized rural tracks, programs, or missions – has challenged schools to accommodate a wider range of stakeholder input. This study examines the reliabilities of main (urban) and regional (rural) campus interviewers’ assessments of applicants to a Rural Physician Leadership Program (RPLP) located in the southeastern United States.

Data from RPLP applicants completing MSPIs on two campuses from 2009-2017 (n = 232) were examined in a generalizability analysis. In two separate …

Increase Staff Utilization Of Occlusive Interface In Micro-Preemie Babies On Bcpap, Deborah A. Igo, Kimberly Kingsley, Faythe Henry, Misty Melendi, Amy Mcbee, Valerie Cook, Christopher Woods, Angela Rojecki, Lauren Walley, Amy Sparks, Stephen Tyzik, Suneela Nayak, Ruth Hanselman

Operations Transformation

Premature neonates born before 26 weeks gestation present many care challenges as they need special precautions to be taken to overcome their fragility. Intubation is often needed for this patient population as their lungs are not fully developed. However, due to their high susceptibility for skin breakdown invasive ventilation often can create subsequent problems. A respiratory therapist team in an academic tertiary medical center wanted to explore the use of an occlusive interface for intubation while providing various forms of non-invasive ventilation in their NICU with the hopes for fewer complications.

The objective of this project was to reduce the …

White Matter Hyperintensity Regression: Comparison Of Brain Atrophy And Cognitive Profiles With Progression And Stable Groups, Omar M. Al-Janabi, Christopher E. Bauer, Larry B. Goldstein, Richard R. Murphy, Ahmed A. Bahrani, Charles D. Smith, Donna M. Wilcock, Brian T. Gold, Gregory A. Jicha

Sanders-Brown Center on Aging Faculty Publications

Subcortical white matter hyperintensities (WMHs) in the aging population frequently represent vascular injury that may lead to cognitive impairment. WMH progression is well described, but the factors underlying WMH regression remain poorly understood. A sample of 351 participants from the Alzheimer’s Disease Neuroimaging Initiative 2 (ADNI2) was explored who had WMH volumetric quantification, structural brain measures, and cognitive measures (memory and executive function) at baseline and after approximately 2 years. Selected participants were categorized into three groups based on WMH change over time, including those that demonstrated regression (n = 96; 25.5%), stability (n = 72; 19.1%), and …

Quinolone Allergy, Edoabasi U. Mcgee, Essie Samuel, Bernadett Boronea, Nakoasha Dillard, Madison N Milby, Susan J Lewis

PCOM Scholarly Works

Quinolones are the second most common antibiotic class associated with drug-induced allergic reactions, but data on quinolone allergy are scarce. This review article discusses the available evidence on quinolone allergy, including prevalence, risk factors, diagnosis, clinical manifestations, cross-reactivity, and management of allergic reactions. Although the incidence of quinolone allergy is still lower than beta-lactams, it has been increasingly reported in recent decades, most likely from its expanded use and the introduction of moxifloxacin. Thorough patient history remains essential in the evaluation of quinolone allergy. Many diagnostic tools have been investigated, but skin tests can yield false-positive results and in vitro …

Mdivi-1, A Mitochondrial Fission Inhibitor, Modulates T Helper Cells And Suppresses The Development Of Experimental Autoimmune Encephalomyelitis., Yan-Hua Li, Fang Xu, Rodolfo Thome, Min-Fang Guo, Man-Luan Sun, Guo-Bin Song, Rui-Lan Li, Zhi Chai, Bogoljub Ciric, A. M. Rostami, Mark T. Curtis, Cun-Gen Ma, Guang-Xian Zhang

Department of Neurology Faculty Papers

BACKGROUND: Unrestrained activation of Th1 and Th17 cells is associated with the pathogenesis of multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis (EAE). While inactivation of dynamin-related protein 1 (Drp1), a GTPase that regulates mitochondrial fission, can reduce EAE severity by protecting myelin from demyelination, its effect on immune responses in EAE has not yet been studied.

METHODS: We investigated the effect of Mdivi-1, a small molecule inhibitor of Drp1, on EAE. Clinical scores, inflammation, demyelination and Drp1 activation in the central nervous system (CNS), and T cell responses in both CNS and periphery were determined.

RESULTS: Mdivi-1 effectively …

Building Health Equity One Institution At A Time: The Research Infrastructure In Minority Institutions Project, Laura H. D'Anna, Dennis G. Fisher, Lyka Eunice F. Trinidad, Carol Canjura, Jefferson L. Wood

Journal of Health Disparities Research and Practice

Developing a well-trained workforce interested in, and prepared for, conducting health equity research is an important national priority. Scientists from Minority-Serving Institutions (MSIs) bring unique perspectives and experiences with racial, ethnic and social inequities in health and health status but often lack access to training and mentoring opportunities, which is crucial for increasing the diverse pool of investigators who are adequately prepared to conduct health disparities research and to compete for National Institutes of Health research funding. The focus of the California State University, Long Beach (CSULB) Research Infrastructure in Minority Institutions (RIMI) Project was to: (a) enhance CSULB’s infrastructure …

“I Don’T Want To Look Sick Skinny”: Perceptions Of Body Image And Weight Loss In Hispanics Living With Hiv In South Texas, Jordan W. Abel, Omar Allen, Delia Bullock, Erin Finley, Elizabeth Walter, Phillip Schnarrs, Barbara S. Taylor

Journal of Health Disparities Research and Practice

Objective: Obesity is rising in people with HIV (PLWH) and Hispanics. Both HIV and obesity are associated with cardiovascular disease morbidity and mortality. Our goal is to understand perceptions of body image and lifestyle in Hispanics with HIV to adapt interventions appropriately.

Methods: We conducted semi-structured interviews with 22 Hispanic PLWH and 6 providers. Purposive sampling selected patient participants across weights and genders. Interviews were coded and analyzed using grounded theory, comparing perspectives between patients with and without obesity, and patients and providers.

Results: Participants felt obesity and diabetes were “normal” in the community. Patients exhibited understanding of healthy diet …

"Courage 2 Test": An Evaluation Of A Social Media Marketing Campaign To Increase Hiv Testing Among Young Black Men, Jamal T. Jones, Laura F. Salazar, Richard A. Crosby

Journal of Health Disparities Research and Practice

The purpose of this study was to evaluate a social media marketing (SMM) campaign designed to increase HIV testing among young Black men attending a public university in Atlanta, GA. “Courage 2 Test” was a three-month SMM campaign (launched from February 2017 to April 2017) that included targeted Facebook and Instagram advertisements to encourage HIV testing. Students completed an online survey via two cross-sectional samples (n=106 at baseline and n=98 post campaign). Campaign evaluation involved assessing the effects of campaign exposure and the pre/post-grouping variable on ever testing for HIV and testing for HIV in the previous six months via …

“You Come Back To The Same Ole Shit:” A Qualitative Study Of Smoking Cessation Barriers Among Women Living With Hiv: Implications For Intervention Development, Faith E. Fletcher, Damon J. Vidrine, Meredith K. Buchberg Trejo, Yamile' Molina, Beverly E. Sha, Brenikki R. Floyd, Noreen Sarhene, Jamesetta Mator, Alicia K. Matthews

Journal of Health Disparities Research and Practice

Although tobacco use among women living with HIV (WLWH) is decreasing, the prevalence is more than double that of women in the general population and remains an important health behavior to target among WLWH. Few smoking cessation interventions specifically focus on the unique social and medical needs of women living with HIV (WLWH). Thus, the investigative team engaged WLWH (N=18) in qualitative focus groups to: 1) understand barriers and facilitators to smoking cessation; and 2) inform intervention structure and content priorities. Participants identified salient reasons for smoking and barriers to smoking cessation, which included coping mechanisms for life stressors, HIV-related …

Implementing Autism Screening For Latino Children In Primary Care: Perspectives From Parents And Providers, Mary Troxel, Keri Linas, Diane Jacobstein, Matthew Biel, Sandra H. Soto, Isabella Lorenzo-Hubert, Soraya Dos-Santos, Rocio Mendez, Bruno J. Anthony

Journal of Health Disparities Research and Practice

While Autism Spectrum Disorder (ASD) and other developmental disabilities are being diagnosed at increasing rates, there is strong evidence of disparities in rates of identification and utilization of services by Latino children as compared to non-Latino children. Attempts to reduce these disparities include culturally-informed early screening for ASD risk. In preparation for initiation of a screening program in a primary care setting serving primarily Latino children, focus groups and interviews were conducted with Latino parents (N=31), medical staff (N=15), health care providers (N=4) to better understand the barriers and facilitators to engagement around developmental concerns that contribute to the low …

A Collaborative Effort To Assess Disparities Associated With Behavioral Health In The North Texas Region, Sushma Sharma

Journal of Health Disparities Research and Practice

Objective: This study aimed to provide an assessment of 16 North Texas Counties’ behavioral health access disparities and provide details of the percentage of hospital patient visits from each county diagnosed with mental health and drug issues. The gender, age, race-ethnicity and insurance status of each patient, the zip codes where they live and patient migration between different providers was also detailed. Furthermore, the number of psychiatric beds for each county is listed.

Methods: This study utilized the DFWHC Foundation's data warehouse which contains comprehensive hospital visit data from 96 partner hospitals, to understand the clinical trends of mental health …

Predictors And Missed Opportunities For Blood Glucose Screening Among African Americans: Implications For Church-Based Populations, Alexandria G. Bauer, Jannette Berkley-Patton, Carole Bowe Thompson, Kelsey Christensen

Journal of Health Disparities Research and Practice

African Americans (AAs) are disproportionately diagnosed with prediabetes, diabetes, and related complications. Guidelines for prediabetes/diabetes screening emphasize reaching at-risk adults. The AA church has potential to increase reach of BGS with AA church members and community members. The current study identified predictors of blood glucose screening (BGS) and individuals with missed opportunities for BGS among church-affiliated AA adults. Participants were drawn from a previous pilot study (Project Faith Influencing Transformation) conducted in six AA churches over eight months. Eligibility criteria included self-identifying as AA and being aged 18 or older. Participants who had previously been diagnosed with diabetes were excluded, …

Disrupting The Intergenerational Transmission Of Trauma Among Alaska Native People: A Conceptual Model For The Family Wellness Warriors Initiative, Lily Ray, Bobbi Outten, Polly Andrews, Katherine Gottlieb

Journal of Health Disparities Research and Practice

Background: Increasing evidence demonstrates the life-long physical, emotional, and social effects of traumatic experiences. In recognition that many health disparities are driven by high rates of traumatic experiences, Alaska Native and American Indian people have created wellness programs that build health by first healing historical and lifetime trauma. Yet, many of these promising community-based interventions are not described in the health sciences literature. Southcentral Foundation’s Family Wellness Warriors Initiative (FWWI) was created by Alaska Native people, addresses traumatic experiences as the root cause of family violence, and builds on cultural strengths. The goal of this study was to build a …

Teaching About Cultural Competence And Health Disparities In An Online Graduate Public Health Course, Anuli Njoku, Drph, Mph, Uchenna Baker, Phd, Med

Journal of Health Disparities Research and Practice

The growing diversity in U.S. society encourages the need for culturally competent healthcare professionals to provide optimal services to a diverse population. This increasing diversity also brings greater awareness to health disparities among distinct subgroups of the U.S. population. Addressing health disparities in the USA will require a multidimensional approach from various sectors, including the field of education. Developing health disparities curricula can help cultivate conscious future health practitioners. Faculty development programs can be integral in equipping faculty to develop curricula on and teach students about health disparities. With a growth in online learning and in the number of adult …