Medicine and Health Sciences Commons^™

2019 October 15 - Medical Student Education Committee Minutes, Medical Student Education Committee, East Tennessee State University

Medical Student Education Committee Minutes

No abstract provided.

Visualization Of The Small Airways:What It Is And Why It Matters, Mark L Schiebler, Grace Parraga

Medical Biophysics Publications

When the earth transitioned to an oxygen-containing atmosphere, many bacterial species were killed by the free radicals that developed in their cytoplasm. New life forms took advantage of this change by evolving to use oxygen as the final resting place for electrons involved in the Krebs cycle. Animals today rely on getting oxygen into the blood stream and getting carbon dioxide out by ventilation through sequentially smaller and smaller tubes until diffusion takes over, finally reaching the terminal respiratory bronchiole and its associated alveoli for gas exchange. All animals are obligate aerobes. One group has estimated that there are 274 …

The Complex Relationship Between Celebrity-Driven Magazines And Depictions Of Fertility At Advanced Reproductive Ages, Brennan Peterson

Marriage and Family Therapy Faculty Articles and Research

"In this issue of the Journal of Women’s Health, Willson and colleagues explore how age and fertility are portrayed in celebrity-driven magazines.¹ Specifically, they examine if popular media depictions of celebrity pregnancies present accurate information related to age and fertility, the use of assisted reproductive technology (ARTs), and pregnancy-related risks associated with advanced maternal age (AMA >35 years). Their study provides an important viewpoint related to the impact of media on reproductive perceptions, and its potential intersection with delayed childbearing, fertility awareness, and reproductive decision making."

Prevalence Of And Factors Associated With Female Sexual Dysfunction Among Women Using Hormonal And Non-Hormonal Contraception At The Aga Khan University Hospital Nairobi, Momin Butt, Valentino Lema, Abraham Mukaindo, Gulnaz Mohamoud, Jacob Shabani

Family Medicine, East Africa

Background: Female sexual function (FSD) is a complex phenomenon. It integrates all body systems and is influenced by a variety of factors. Contraceptives have shown to have variable effects on FSD. In Kenya, the majority of women use hormonal contraception with high rates of discontinuation of use, attributed to related side effects such as weight loss and loss of libido.

Aim: To determine the prevalence of and the factors affecting FSD among women using contraception in our setting.

Setting: The study was carried out at the Aga Khan University Hospital, Nairobi, at various clinical sites.

Methods: A cross-sectional study was …

Heterogeneity And Plasticity Of Human Breast Cancer Cells In Response To Molecularly-Targeted Drugs, Emira Bousoik, Ramina Nabiee, Farideh Amirrad, Ashley Nichols, Rebecca Witt, Parvin Mahdipoor, Hamidreza Montazeri Aliabadi

Pharmacy Faculty Articles and Research

Non-responsive subpopulation of tumor cells, and acquired resistance in initially responsive cells are major challenges for cancer therapy with molecularly-targeted drugs. While point mutations are considered the major contributing factor to acquired resistance, in this study we explored the role of heterogeneity and plasticity of selected human breast cancer cell lines (MDA-MB-231, MDA-MB-468, and AU565) in their initial and adjusted response, respectively, to ruxolitinib, everolimus, and erlotinib. After determination of lethal concentration for 50% cell death (LC50), cells were exposed to selected drugs using three different approaches: single exposure to 4 × LC50 and collection of surviving cells, multiple exposures …

Trends In The Timeliness Of Hiv Diagnosis And Antiretroviral Treatment Initiation Before, During And After The “Treat All” Recommendation – New York City, 2006 - 2015, Mckaylee Robertson

Dissertations and Theses

BACKGROUND: Voluntary HIV testing followed by immediate antiretroviral treatment (ART) initiation (universal testing and treatment) has become an integral part of strategies to eliminate HIV and control the HIV/AIDS epidemic. Minimizing the time from HIV infection to ART initiation is essential for universal test and treatment to be optimally effective. In New York City, an epicenter of the HIV epidemic, the ‘treat all’ recommendation, immediate treatment for all people diagnosed with HIV, was made in late 2011, and efforts to ‘treat all’ were contemporaneous with large scale HIV testing initiatives in NYC. The overarching goal of this dissertation was to …

Understanding Multigenerational Nurse-Faculty-Collaboration Strategies-A Delphi Study, Heather M. Fowler

Nursing Theses and Dissertations

Four distinct generations have come together to work cooperatively, producing higher quality nursing students who are engaged and satisfied in their learning experience from nursing faculty. The multigenerational nursing faculty workforce must learn to work together through positive collaboration, using teamwork strategies, and decreasing conflict and negative influences in the workplace. Strauss and Howe’s (1991) generational-cycle model depicted four archetypes that recur throughout history every 22 years; the life stages of generations provided the foundation for this study. Generations can come together if they understand what various generational cohorts perceive as positive collaboration factors, teamwork strategies, and negative influences. A …

Camptothecin-Based Dendrimersomes For Gene Delivery And Redox-Responsive Drug Delivery To Cancer Cells, Partha Laskar, Sukrut Somani, Sarah Jane Campbell, Margaret Mullin, Patricia Keating, Rothwelle J. Tate, Craig Irving, Hing Y. Leung, Christine Dufès

School of Medicine Publications

Combination therapy involving chemotherapeutic drugs and genes is emerging as a promising strategy to provide a synergistic therapeutic effect, to overcome drug resistance while reducing the severe side effects associated with conventional chemotherapeutic drugs. However, the lack of nanomedicines able to simultaneously carry anti-cancer drugs and nucleic acids limits the application of this therapeutic strategy. To overcome this issue, we proposed to synthesize a pro-drug dendrimer by conjugating the PEGylated, positively charged generation 3-diaminobutyric polypropylenimine dendrimer to the anti-cancer drug camptothecin with a redox-sensitive disulphide linkage, and evaluate its efficacy to co-deliver the complexed DNA and camptothecin to cancer cells. …

Development Of A Non-Invasive Device For Swallow Screening In Patients At Risk Of Oropharyngeal Dysphagia: Results From A Prospective Exploratory Study, Catriona M. Steele, Rajat Mukherjee, Juha M. Kortelainen, Harri Pölönen, Michael Jedwab, Susan L. Brady, Kayla Brinkman Theimer, Susan Langmore, Luis F. Riquelme, Nancy B. Swigert, Philip M. Bath, Larry B. Goldstein, Richard L. Hughes, Dana Leifer, Kennedy R. Lees, Atte Meretoja, Natalia Muehlemann

Neurology Faculty Publications

Oropharyngeal dysphagia is prevalent in several at-risk populations, including post-stroke patients, patients in intensive care and the elderly. Dysphagia contributes to longer hospital stays and poor outcomes, including pneumonia. Early identification of dysphagia is recommended as part of the evaluation of at-risk patients, but available bedside screening tools perform inconsistently. In this study, we developed algorithms to detect swallowing impairment using a novel accelerometer-based dysphagia detection system (DDS). A sample of 344 individuals was enrolled across seven sites in the United States. Dual-axis accelerometry signals were collected prospectively with simultaneous videofluoroscopy (VFSS) during swallows of liquid barium stimuli in thin, …

October 2019, Randy Curry, Cindy Brooks

RURAL ROCKS

Rural Rocks, the Rural Health Network newsletter by the SWOSU College of Pharmacy

Current Practice Patterns In The Diagnosis And Management Of Sleep-Disordered Breathing In Infants., Rachana Kombathula, David G. Ingram Md, Zarmina Ehsan Md

Manuscripts, Articles, Book Chapters and Other Papers

STUDY OBJECTIVES: Currently, there are no universally accepted guidelines for diagnosis and management of sleep-disordered breathing (SDB) in infants. The purpose of this study was to survey pediatric sleep medicine providers regarding their current practice patterns for diagnosis and management of SDB in infants.

METHODS: An anonymous, web-based survey with 71 questions was distributed via the PEDSLEEP and Ped-Lung listserv, which serve as a hub of communication for pediatric sleep and pulmonary medicine providers worldwide.

RESULTS: Fifty-four providers from eight countries completed the survey. Ninety-six percent of providers reported performing sleep studies in infants with 53% performing more than 30 …

Rumination Selectively Mediates The Association Between Actual-Ideal (But Not Actual-Ought) Self-Discrepancy And Anxious And Depressive Symptoms, Joanne M. Dickson, Nicholas J. Moberly, Christopher D. Huntley

Research outputs 2014 to 2021

Actual-ideal and actual-ought self-discrepancies have been theorised to be independently associated with depressive and anxious symptoms respectively. This study tested this prediction and extended it to consider whether rumination mediates these relationships. One hundred and thirty-eight students (48 males, 90 females) listed four adjectives describing how they would ideally hope to be and four adjectives describing how they ought to be. Participants then rated how distant they perceived themselves to be from each of their ideal and ought selves, as well as the importance of each ideal and ought self. Finally, participants self-reported levels of negative rumination, anxious and depressive …

What's Happening: October 14, 2019, Maine Medical Center

What's Happening

No abstract provided.

Using The System Of Care Approach To Distinguish School Refusal From School Truancy, Connie Chang, Md, Aneela Khan, Md

Department of Psychiatry and Human Behavior Posters

Learning Objectives

To recognize the importance of taking a system of care approach to determine whether the symptoms of school avoidance are due to mental illness

Comparison Of Mri- And Trus-Informed Prostate Biopsy For Prostate Cancer Diagnosis In Biopsy-Naive Men: A Systematic Review And Meta-Analysis., Hanan Goldberg, Ardalan E. Ahmad, Thenappan Chandrasekar, Laurence Klotz, Mark Emberton, Masoom A. Haider, Samir S. Taneja, Karan Arora, Neil Fleshner, Antonio Finelli, Nathan Perlis, Mark D. Tyson, Zachary Klaassen, Christopher J.D. Wallis

Department of Urology Faculty Papers

PURPOSE: Multiparametric magnetic resonance imaging (mpMRI) with informed targeted biopsies (TGBX) has changed the paradigm of prostate cancer (PCa) diagnosis. Randomized studies have demonstrated a diagnostic benefit of Clinically significant (CS) for TGBX compared to standard systematic biopsies (SBX). We aimed to evaluate whether mpMRI-informed TGBX has superior diagnosis rates of any-, CS-, high-grade (HG)-, and clinically insignificant (CI)-PCa compared to SBX in biopsy-naive men.

METHODS: Data was searched in Medline, Embase, Web of Science, and Evidence-based medicine reviews-Cochrane Database of systematic reviews from database inception until 2019. Studies were selected by two authors independently, with disagreements resolved by consensus …

Research, Reflections, And Resistance: A Review Of Body Battlegrounds: Transgressions, Tensions, And Transformations, Alexandra Ch Nowakowski

The Qualitative Report

Body Battlegrounds: Transgressions, Tensions, and Transformations offers a superb learning resource for exploring the body in social, emotional, cultural, and political contexts across many different career stages and disciplines. Edited by seasoned embodiment scholars Dr. Chris Bobel and Dr. Samantha Kwan, this new collection brings together 13 research reflections and 16 personal essays on different aspects of embodied resistance. It offers an expansive view of intersecting forms of body marginalization and ways to center these experiences in seeking embodiment justice. It also makes a superb resource for orienting learners at all career stages to embodied resistance and its crucial role …

I Spy With My Little Eye … A Knee About To Go 'Pop'? Can Coaches And Sports Medicine Professionals Predict Who Is At Greater Risk Of Acl Rupture?, Anne Inger Mørtvedt, Tron Krosshaug, Roald Bahr, Erich Petushek

Michigan Tech Publications, Part 1

BACKGROUND: The vertical drop jump (VDJ) test is widely used for clinical assessment of ACL injury risk, but it is not clear whether such assessments are valid.

AIM: To examine if sports medicine professionals and coaches are able to identify players at risk of sustaining an ACL injury by visually assessing player performance during a VDJ test.

METHODS: 102 video clips of elite female handball and football players performing a baseline VDJ test were randomly extracted from a 738-person prospective cohort study that tracked ACL injuries. Of the sample, 20 of 102 went on to suffer an ACL injury. These …

Medical School Watercooler Newsletter - October 13, 2019, Lindsey Lyle

Watercooler Newsletter

This is the October 13, 2019 edition of the Frederick P. Whiddon College of Medicine's Newsletter - Watercooler.

Contents Include:

Trimm to present on implicit bias at OB/GYN grand rounds

USA basic medical sciences graduate student research published

Mark Your Calendar: Scalici to present at surgery (88) ground rounds

Professor’s memoir teaches lessons in running, cancer and life

Creativity, Experience, And Reflection: One Magic Formula To Develop Preventive Water Competences, Ana I. Ortiz Olivar

International Journal of Aquatic Research and Education

Preventive water competences that children should learn to be safe in the water have been discussed and revised. Methodology to promote these wáter competences has not had the same amount of examination and discussion so far. From an ecological perspective, we share some key points derived from the objectives of the research-into-action program called “The development of preventive water competences in 5th and 6th grade school students” as conducted in Junior Lifeguard programs in Uruguay. It involved six groups of 10 to 12-year-old Estate School students studied in two cycles. The whole process conveyed how our methodology changed from experiences …

Incorporating Mpmri Biopsy Data Into Established Pre-Rp Nomograms: Potential Impact Of An Increasingly Common Clinical Scenario, Joon Yau Leong, Jaime O. Herrera-Caceres, Hanan Goldberg, Elwin Tham, Seth Teplitsky, Leonard G. Gomella, Neil E. Fleshner, Costas D. Lallas, Edouard J. Trabulsi, Thenappan Chandrasekar

Department of Urology Faculty Papers

Background: We examine the practical application of multiparametric MRI (mpMRI) prostate biopsy data using established pre-RP nomograms and its potential implications on RP intraoperative decision-making. We hypothesize that current nomograms are suboptimal in predicting outcomes with mpMRI targeted biopsy (TBx) data.

Materials and methods: Patients who underwent mpMRI-based TBx prior to RP were assessed using the MSKCC and Briganti nomograms with the following iterations: (1) Targeted (T) (targeted only), (2) Targeted and Systematic (TS) and (3) Targeted Augmented (TA) (targeted core data; assumed negative systematic cores for 12 total cores). Nomogram outcomes, lymph node involvement (LNI), extracapsular extension (ECE), organ-confined …

Association Between The Seated Single-Arm Shot-Put Test With Isokinetic Pushing Force, Bryan L. Riemann, George J. Davies

Health Sciences & Kinesiology: Faculty Publications

Context: Previous investigations have examined the reliability, normalization, and underlying projection mechanics of the seated single-arm shot-put (SSASP) test. Although the test is believed to reflect test limb strength, there have been no assessments determining whether test performance is directly associated with upper-extremity strength. Objective: To determine the relationship between isokinetic pushing force and SSASP performance and conduct a method comparison analysis of limb symmetry indices between the 2 tests. Design: Controlled laboratory study. Setting: Biomechanics laboratory. Patients (or Other Participants): Twenty-four healthy and physically active men (n = 12) and women (n = 12). Intervention(s): Participants completed the SSASP …

Going It Alone: Successes And Failures Developing A Single-Staff Systematic Review Service, Jenessa Mcelfresh

Southern Chapter/Medical Library Association Annual Conference

Objective: The purpose of this study is to document the successes and failures of solely developing and supporting a systematic review consultation service. While these insights are specific to the systematic review service creation process, the tips can be applied to any service idea met with high demand and little resources.

Methods: The systematic review service described in this study was developed at a non-health sciences specific university library at a Carnegie-R1 research institution. The service has a multi-tiered approach created using best practices identified from systematic review services offered at other institutions, and the strengths and weaknesses of the …

Squircle: One Month To Renegotiate License Agreements And Pricing To Include New Hospital Acquisitions, Jean Gudenas

Southern Chapter/Medical Library Association Annual Conference

Objective: To develop an adhoc workflow for renegotiating license agreements and pricing to support the medical center’s acquisition of new hospitals.

Methods: In reaction to the acquisition of new hospitals, the Library had to develop an adhoc workflow to inform vendors of the newly acquired hospitals, update license agreements, renegotiate pricing, and negotiate a funding increase to a shared services agreement. Collaborating with the Health System Administration Planning Team (HSAPT), a timeline was established as to when the hospitals would receive access to various services, including all library-subscribed and purchased material.

Results: The project timeline had a go-live date of …

Preimplantation Genetic Testing (Pgt) And Frozen Embryo Transfer (Fet) Synergistically Decrease Pre-Term Delivery In Patients Undergoing In Vitro Fertilization (Ivf), Luke Ying Md, Mark Sanchez Md, James Baron Md, Ying Ying

OB-GYN

OBJECTIVE: To study the effects of FET and FET post PGT (FET/PGT) on pre-term and very pre-term deliveries in patients undergoing IVF with elective single embryo transfer (eSET).

DESIGN: Retrospective cohort Society for Assisted Reproductive Technology (SART) data study.

MATERIALS AND METHODS: A retrospective cohort study was conducted using the publicly available data in the SART National Summary Report from 2014 to 2017. Cycle inclusion criteria were eSET, fresh embryo transfers (ET), and frozen embryo transfers (FET) with or without PGT (FET/PGT). Exclusion criteria were use of gestational carriers and donor eggs. Pregnancy outcomes included live births and gestational age …

Moyamoya Disease Presenting With Stroke, Timothy Collins, Chimezie Ubbaonu, Phuong Vo

Internal Medicine

No abstract provided.

Choking On Adenocarcinoma, Andre Sahakian Md, Rajesh Gulati Md

Internal Medicine

No abstract provided.

So Much Soma, Satvir Dhillon Md, Gregory Shimizu Md

Internal Medicine

No abstract provided.

Any Shape Or Form: An Online Module For Teaching Medical Students Citation Management In Residency Settings, Erica Heasley, Robyn Rosasco

Southern Chapter/Medical Library Association Annual Conference

Objective: To describe how the library’s online tutorial for medical students, “Introduction to Citation Management Tools,” was created and integrated into the College of Medicine’s Residency Preparation Boot Camp. Implemented in 2017, passing the tutorial is still a requirement for completing the boot camp.

Methods: In 2017, the Maguire Medical Library was asked by undergraduate and graduate medical education faculty to create a citation management tutorial for 4th-year medical students preparing to commence their respective residency programs. As part of the College of Medicine’s Residency Preparation Boot Camp, the tutorial needed to provide students with an overview of citation management …

A Librarian's Perspective On Manually Tagging Curriculum For Lcme Accreditation, Melodie Gardner

Southern Chapter/Medical Library Association Annual Conference

Objective: The objective of this paper is to discuss and share some of the successes and challenges of manually tagging all first- and second-year (M1/M2) curriculum course sessions over the course of five academic years (2014 - 2019).

Methods: As part of the Liaison Committee on Medical Education (LCME) accreditation process, all US medical schools are required to maintain a curriculum database that tracks the number of course hours spent on a selected set of topics outlined in the LCME Functions and Structures of a Medical School; this is usually achieved by building a controlled vocabulary based on Standard 6 …

Shaping The Future Of Information Literacy Research By Health Sciences Librarians: A Bibliometric Study, Alexandria Quesenberry, Lin Wu

Southern Chapter/Medical Library Association Annual Conference

Objectives: Information literacy (IL) publications have been examined in many disciplines, but there is limited published literature to assess health sciences librarians’ productivity on IL research. This study aimed to examine the status and characteristics of IL research authored by health sciences librarians over the period of 2008 to 2018.

Methods: Bibliometrics, the statistical analysis of publications, was used to assess the indicators of productivity, collaboration, and visibility on IL research by health sciences librarians. Data was collected from Scopus and Web of Science. EndNote software was used to remove duplicates and Rayyan was used to systematically screen search results …