Medicine and Health Sciences Commons^™

Teaching Visually Impaired College Students In Introductory Statistics, Brian W. Stone, Donovan Kay, Anthony Reynolds

Psychological Sciences Faculty Publications and Presentations

Instructors of postsecondary classes in statistics rely heavily on visuals in their teaching, both within the classroom and in resources like textbooks, handouts, and software, but this information is often inaccessible to students who are blind or visually impaired (BVI). The unique challenges involved in adapting both pedagogy and course materials to accommodate a BVI student may provoke anxiety among instructors teaching a BVI student for the first time, and instructors may end up feeling unprepared or “reinventing the wheel.” We discuss a wide variety of accommodations inside and outside of the classroom grounded in the empirical literature on cognition …

Effects Of Naltrexone On Alcohol And Nicotine Use In Female P Rats, Usman Z. Hamid, Sarah E. Maggio, Meredith A. Saunders, Kimberly Nixon, Mark A. Prendergast, Richard L. Bell, Michael T. Bardo

Posters-at-the-Capitol Presentations

The objective of the present study was to determine the effectiveness of the opioid antagonist naltrexone at reducing the consumption of EtOH and nicotine in female alcohol-preferring (P) rats. P rats have been selectively bred to have a genetic predisposition for alcohol abuse, which allows them to be used as an animal model of alcoholism. P rats readily self-administer i.v nicotine (Le et al., 2016), have EtOH consumption during adolescence that is similar to that seen in adulthood, and operantly respond for EtOH until they are impaired/intoxicated (Bell et al., 2006). Thus, P rats are a useful model for studying …

Lead Exposure And Metabolic Syndrome In U.S. Population, Nhanes 2013-2014, Khadra Gukadowr

Master of Public Health Program Student Publications

Background: Lead is a known endocrine disruptor and can impair regulation of blood glucose, blood pressure, abdominal adiposity, blood lipid levels which are risk factors for metabolic syndrome (MetS).

Objective: To study the association of lead exposure and MetS in United States (U.S.) adults.

Methods: Data from 523 male and 528 female participants aged 20 years and older from the 2013 to 2014 National Health and Nutrition Examination Survey (NHANES) were analyzed. Based on blood lead distribution in males and females, participants were categorized into low and high blood lead groups in both genders. Adjusted logistic regression analysis was used …

Who Is Testing? Demographic And Sexual Risk Factors Associated With Hiv Testing Among African American College Students, Elizabeth Gonder-Strutz

Master of Public Health Program Student Publications

Despite significant progress made in reducing HIV diagnoses, many populations are still disproportionately affected. Although African American college students tend to engage in safer sex practices than their peers, they are still at an elevated risk for contracting HIV. Therefore, it is important that HIV prevention programs understand the unique needs and risk factors among African American college students. HIV testing is an essential component of HIV prevention. This study examined the relationship between HIV testing and demographic and behavioral factors among African American college students from two universities. The study found that older students (upperclassmen) are significantly more likely …

Vital Signs, Winter 2019, Boonshoft School Of Medicine

Vital Signs

A thirty-two page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

Systemic Sclerosis Presenting With Bilateral Retinal Cotton Wool Spots, Christina E. Borchers, Ronald E. Warwar

Dermatology Faculty Publications

Systemic sclerosis is a systemic inflammatory diseasecharacterized by a triad of autoimmune reactions,vasculopathy, and fibrosis due to collagen deposition. Thediffuse sclerosis type includes vascular abnormalities in theskin (puffy, taut, thickened skin, pitting of fingertips), soft tissues(arthralgias, myalgias), lungs (pulmonary hypertension,interstitial fibrosis), gastrointestinal tract (esophagealdysmotility, GERD), kidneys (scleroderma renal crisis), andheart (arrhythmias, heart failure).Rarely, systemic sclerosis can present with signs of retinalvascular occlusion and cotton wool spots in the eyes. Thefollowing case report describes a patient presenting with cottonwool spots as an early manifestation of systemic sclerosis.

Kiaa1549-Braf Expression Establishes A Permissive Tumor Microenvironment Through Nfκb-Mediated Ccl2 Production, Ran Chen, Chanel Keoni, Christopher A. Waker, Robert M. Lober, Robert M. Lober, Yihsien Chen, David H. Gutmann

Pediatrics Faculty Publications

KIAA1549-BRAF is the most frequently identified genetic mutation in sporadic pilocytic astrocytoma (PA), creating a fusion BRAF (f-BRAF) protein with increased BRAF activity. Fusion-BRAF-expressing neural stem cells (NSCs) exhibit increased cell growth and can generate glioma-like lesions following injection into the cerebella of naïve mice. Increased Iba1+ monocyte (microglia) infiltration is associated with murine f-BRAF-expressing NSC-induced glioma-like lesion formation, suggesting that f-BRAF-expressing NSCs attract microglia to establish a microenvironment supportive of tumorigenesis. Herein, we identify Ccl2 as the chemokine produced by f-BRAF-expressing NSCs, which is critical for creating a permissive stroma for gliomagenesis. In addition, f-BRAF regulation of Ccl2 production …

Next-Generation Sequencing Of Hiv-1 Single Genome Amplicons, Gustavo H. Kijak, Eric Sanders-Buell, Phuc Pham, Elizabeth A. Harbolick, Celina Oropeza, Anne Marie O'Sullivan, Meera Bose, Charmagne G. Beckett, Mark Milazzo, Merlin L. Robb, Sheila A. Peel, Paul T. Scott, Nelson L. Michael, Adam W. Armstrong, Jerome H. Kim, David Brett-Major, Sodsai Tovanabutra

Journal Articles: Epidemiology

The analysis of HIV-1 sequences has helped understand the viral molecular epidemiology, monitor the development of antiretroviral drug resistance, and design candidate vaccines. The introduction of single genome amplification (SGA) has been a major advancement in the field, allowing for the characterization of multiple sequences per patient while preserving linkage among polymorphisms in the same viral genome copy. Sequencing of SGA amplicons is performed by capillary Sanger sequencing, which presents low throughput, requires a high amount of template, and is highly sensitive to template/primer mismatching. In order to meet the increasing demand for HIV-1 SGA amplicon sequencing, we have developed …

Using "Outbreak Science" To Strengthen The Use Of Models During Epidemics., Caitlin Rivers, Jean-Paul Chretien, Steven Riley, Julie A. Pavlin, Alexandra Woodward, David Brett-Major, Irina Maljkovic Berry, Lindsay Morton, Richard G. Jarman, Matthew Biggerstaff, Michael A. Johansson, Nicholas G. Reich, Diane Meyer, Michael R. Snyder, Simon Pollett

Journal Articles: Epidemiology

Infectious disease modeling has played a prominent role in recent outbreaks, yet integrating these analyses into public health decision-making has been challenging. We recommend establishing ‘outbreak science’ as an inter-disciplinary field to improve applied epidemic modeling.

New Filovirus Disease Classification And Nomenclature, Jens H. Kuhn, Takuya Adachi, Neill K.J. Adhikari, Jose R. Arribas, Ibrahima Elhadj Bah, Daniel G. Bausch, Nahid Bhadelia, Matthias Borchert, Arne Broch Brantsæter, David Brett-Major, Timothy H. Burgess, Daniel S. Chertow, Christopher G. Chute, Theodore J. Cieslak, Robert Colebunders, Ian Crozier, Richard T. Davey, Hilde De Clerck, Rafael Delgado, Laura Evans, Mosoka Fallah, William A. Fischer, Tom E. Fletcher, Robert A. Fowler, Thomas Grünewald, Andy Hall, Angela L. Hewlett, Andy I.M. Hoepelman, Catherine F. Houlihan, Giuseppe Ippolito, Shevin T. Jacob, Michael Jacobs, Robert Jakob, Frederique A. Jacquerioz, Laurent Kaiser, Andre C. Kalil, Rashidatu F. Kamara, Jimmy Kapetshi, Hans-Dieter Klenk, Gary Kobinger, Mark G. Kortepeter, Colleen S. Kraft, Thomas Kratz, Henry S. Kyobe Bosa, Marta Lado, François Lamontagne, H. Cliff Lane, Leslie Lobel, Julius Lutwama, G. Marshall Lyon, Moses B.F. Massaquoi, Thomas A. Massaquoi, Aneesh K. Mehta, Vital Mondonge Makuma, Srinivas Murthy, Tonny Seikikongo Musoke, Jean-Jacques Muyembe-Tamfum, Phiona Nakyeyune, Carolina Nanclares, Miriam Nanyunja, Justus Nsio-Mbeta, Tim O'Dempsey, Janusz T. Pawęska, Clarence J. Peters, Peter Piot, Christophe Rapp, Bertrand Renaud, Bruce Ribner, Pardis C. Sabeti, John S. Schieffelin, Werner Slenczka, Moses J. Soka, Armand Sprecher, James Strong, Robert Swanepoel, Timothy M. Uyeki, Michel Van Herp, Pauline Vetter, David A. Wohl, Timo Wolf, Anja Wolz, Alie H. Wurie, Zabulon Yoti

Journal Articles: Epidemiology

The recent large outbreak of Ebola virus disease (EVD) in Western Africa resulted in greatly increased accumulation of human genotypic, phenotypic and clinical data, and improved our understanding of the spectrum of clinical manifestations. As a result, the WHO disease classification of EVD underwent major revision.

De Novo Assembly Of The Brugia Malayi Genome Using Long Reads From A Single Minion Flowcell, Joseph R. Fauver, John Martin, Gary J. Weil, Makedonka Mitreva, Peter U. Fischer

Journal Articles: Epidemiology

Filarial nematode infections cause a substantial global disease burden. Genomic studies of filarial worms can improve our understanding of their biology and epidemiology. However, genomic information from field isolates is limited and available reference genomes are often discontinuous. Single molecule sequencing technologies can reduce the cost of genome sequencing and long reads produced from these devices can improve the contiguity and completeness of genome assemblies. In addition, these new technologies can make generation and analysis of large numbers of field isolates feasible. In this study, we assessed the performance of the Oxford Nanopore Technologies MinION for sequencing and assembling the …

Primary Cardiac Sarcoma: A Rare, Aggressive Malignancy With A High Propensity For Brain Metastases., Brittany L Siontis, Lili Zhao, Monika Leja, Jonathan B Mchugh, Maryann M Shango, Laurence H Baker, Scott M Schuetze, Rashmi Chugh

Articles, Abstracts, and Reports

Introduction: Primary cardiac sarcoma (PCS) has a poor prognosis compared to other sarcomas due to late presentation, challenging resection, incidence of metastases, and limited efficacy of systemic therapies.

Methods: A medical record search engine was queried to identify patients diagnosed with PCS from 1992 to 2017 at the University of Michigan.

Results: Thirty-nine patients with PCS had a median age of 41 years (range 2-77). Common histologies were angiosarcoma (AS, 14), high-grade undifferentiated pleomorphic sarcoma (UPS, 10), and leiomyosarcoma (LMS, 5). Sites of origin were left atrium (18), right atrium (16), and pericardium (5). AS was the most common right-sided …

01. Exhibit Title (Exhibit Panel - Doctors And Nurses As Rescuers In Humanitarian Crises), Stephen Gaies

Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition

This file is the "Exhibit Title" panel, which is a part of the exhibit entitled "Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition" shown at the Grout Museum in Waterloo, Iowa in 2019 and 2020.

03. Susan La Flesche Picotte (Exhibit Panel - Doctors And Nurses As Rescuers In Humanitarian Crises), Stephen Gaies

Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition

This file is the "Susan La Flesche Picotte" panel, which is a part of the exhibit entitled "Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition" shown at the Grout Museum in Waterloo, Iowa in 2019 and 2020.

To see the supplemental information, click the Related Work button.

05. Bodil Katharine Biørn (Exhibit Panel - Doctors And Nurses As Rescuers In Humanitarian Crises), Stephen Gaies

Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition

This file is the "Bodil Katharine Biørn" panel, which is a part of the exhibit entitled "Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition" shown at the Grout Museum in Waterloo, Iowa in 2019 and 2020.

To see the supplemental information, click the Related Work button.

04. Floyd Olin Smith (Exhibit Panel - Doctors And Nurses As Rescuers In Humanitarian Crises), Stephen Gaies

Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition

This file is the "Floyd Olin Smith" panel, which is a part of the exhibit entitled "Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition" shown at the Grout Museum in Waterloo, Iowa in 2019 and 2020.

To see the supplemental information, click the Related Work button.

06. Jakob Künzler (Exhibit Panel - Doctors And Nurses As Rescuers In Humanitarian Crises), Stephen Gaies

Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition

This file is the "Jakob Künzler" panel, which is a part of the exhibit entitled "Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition" shown at the Grout Museum in Waterloo, Iowa in 2019 and 2020.

To see the supplemental information, click the Related Work button.

02. Introduction (Exhibit Panel - Doctors And Nurses As Rescuers In Humanitarian Crises), Stephen Gaies

Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition

This file is the "Introduction" panel, which is a part of the exhibit entitled "Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition" shown at the Grout Museum in Waterloo, Iowa in 2019 and 2020.

08. Robert O. Wilson (Exhibit Panel - Doctors And Nurses As Rescuers In Humanitarian Crises), Stephen Gaies

Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition

This file is the "Robert O. Wilson" panel, which is a part of the exhibit entitled "Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition" shown at the Grout Museum in Waterloo, Iowa in 2019 and 2020.

To see the supplemental information, click the Related Work button.

09. Eugeniusz Łazowski (Exhibit Panel - Doctors And Nurses As Rescuers In Humanitarian Crises), Stephen Gaies

Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition

This file is the "Eugeniusz Łazowski" panel, which is a part of the exhibit entitled "Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition" shown at the Grout Museum in Waterloo, Iowa in 2019 and 2020.

To see the supplemental information, click the Related Work button.

10. Adelaide Hautval (Exhibit Panel - Doctors And Nurses As Rescuers In Humanitarian Crises), Stephen Gaies

Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition

This file is the "Adelaide Hautval" panel, which is a part of the exhibit entitled "Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition" shown at the Grout Museum in Waterloo, Iowa in 2019 and 2020.

To see the supplemental information, click the Related Work button.

11. Rudolf Stefan Weigl (Exhibit Panel - Doctors And Nurses As Rescuers In Humanitarian Crises), Stephen Gaies

Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition

This file is the "Rudolf Stefan Weigl" panel, which is a part of the exhibit entitled "Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition" shown at the Grout Museum in Waterloo, Iowa in 2019 and 2020.

To see the supplemental information, click the Related Work button.

13. Madeleine Pauliac (Exhibit Panel - Doctors And Nurses As Rescuers In Humanitarian Crises), Stephen Gaies

Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition

This file is the "Madeleine Pauliac" panel, which is a part of the exhibit entitled "Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition" shown at the Grout Museum in Waterloo, Iowa in 2019 and 2020.

To see the supplemental information, click the Related Work button.

12. Julius De Clercq Zubli (Exhibit Panel - Doctors And Nurses As Rescuers In Humanitarian Crises), Stephen Gaies

Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition

This file is the "Julius de Clercq Zubli" panel, which is a part of the exhibit entitled "Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition" shown at the Grout Museum in Waterloo, Iowa in 2019 and 2020.

To see the supplemental information, click the Related Work button.

14. The Doctors Of Srebrenica (Exhibit Panel - Doctors And Nurses As Rescuers In Humanitarian Crises), Stephen Gaies

Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition

This file is "The Doctors of Srebrenica" panel, which is a part of the exhibit entitled "Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition" shown at the Grout Museum in Waterloo, Iowa in 2019 and 2020.

To see the supplemental information, click the Related Work button.

15. Philippe Gaillard (Exhibit Panel - Doctors And Nurses As Rescuers In Humanitarian Crises), Stephen Gaies

Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition

This file is the "Philippe Gaillard" panel, which is a part of the exhibit entitled "Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition" shown at the Grout Museum in Waterloo, Iowa in 2019 and 2020.

To see the supplemental information, click the Related Work button.

16. Denis Mukwege (Exhibit Panel - Doctors And Nurses As Rescuers In Humanitarian Crises), Stephen Gaies

Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition

This file is the "Denis Mukwege" panel, which is a part of the exhibit entitled "Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition" shown at the Grout Museum in Waterloo, Iowa in 2019 and 2020.

To see the supplemental information, click the Related Work button.

17. The Doctors Of Aleppo (Exhibit Panel - Doctors And Nurses As Rescuers In Humanitarian Crises), Stephen Gaies

Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition

This file is "The Doctors of Aleppo" panel, which is a part of the exhibit entitled "Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition" shown at the Grout Museum in Waterloo, Iowa in 2019 and 2020.0.

To see the supplemental information, click the Related Work button.

03. Susan La Flesche Picotte Supplemental Information, Stephen Gaies

Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition

Supplemental information for the Susan La Flesche Picotte exhibit panel.

To see the associated exhibit panel, click the Related Work button.

04. Floyd Olin Smith Supplemental Information, Stephen Gaies

Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition

Supplemental information for the Floyd Olin Smith exhibit panel.

To see the associated exhibit panel, click the Related Work button.