Medicine and Health Sciences Commons^™

Addressing The Treatment And Recovery Support Needs Of Individuals With Opioid Use Disorder: Patient Perspectives, Mary Lindsey Smith Phd, Katie Rosingana Ba, Rachel M. Gallo Mph, Frances Jimenez Ba, Mark Richards Ba

Substance Use Research & Evaluation

No abstract provided.

Human Macular Müller Cells Rely More On Serine Biosynthesis To Combat Oxidative Stress Than Those From The Periphery, Ting Zhang, Ling Zhu, Michele C. Madigan, Wei Liu, Weiyong Shen, Svetlana Cherepanoff, Fanfan Zhou, Shaoxue Zeng, Jianhai Du, Mark C. Gillies

Faculty & Staff Scholarship

Abstract The human macula is more susceptible than the peripheral retina to developing blinding conditions such as age-related macular degeneration, diabetic retinopathy. A key difference between them may be the nature of their Mu¨ ller cells. We found primary cultured Mu¨ ller cells from macula and peripheral retina display significant morphological and transcriptomic differences. Macular Mu¨ ller cells expressed more phosphoglycerate dehydrogenase (PHGDH, a rate-limiting enzyme in serine synthesis) than peripheral Mu¨ ller cells. The serine synthesis, glycolytic and mitochondrial function were more activated in macular than peripheral Mu¨ ller cells. Serine biosynthesis is critical in defending against oxidative stress. …

Time To Achievement Of Mean Arterial Pressure Goal In Patients With Septic Shock Based On Initial Norepinephrine Dose, Meagan R. Ellinger Pharmd, Dustin D Linn Pharmd, Bcps, Bcccp, Michael Todt Pharmd, Bccp

Parkview Pharmacy Department

Poster Presentation

2019 ASHP Midyear Clinical Meeting / Las Vegas, Nevada / Poster # 11-133

Objective: Evaluate whether the initial norepinephrine dose in septic shock patients is associated with the time to achievement of MAP goal

Acute Exercise And Mindfulness Meditation On Learning And Memory: Randomized Controlled Intervention, Malina Austin, Paul D. Loprinzi

Faculty and Student Publications

© 2019 The Author(s). Background: The purpose of this experiment was to evaluate the potential combined effects of acute exercise and mindfulness mediation on episodic memory. Methods: All data collection occurred in the authors’ laboratory (January to May of 2019). In this three-arm, within-subject design, participants (N=20; Mage=21.6 years) completed three counterbalanced laboratory visits, including Exercise Only, Exercise + Meditation and Control. Learning and memory were assessed from a word-list task. A one-factor repeated-measures ANOVA was computed for two memory outcomes, including the learning outcome (average performance across the 6 trials) and the long-term memory recall (10-minute delay). Results: The …

Evaluation Of An Adjusted Body Weight Based Heparin Protocol, Jenna Deininger Pharmd, Elizabeth Meisberger Pharmd, Bcps, Kris Howard Pharmd, Bcps

Parkview Pharmacy Department

Poster Presentation

2019 ASHP Midyear Clinical Meeting/ Las Vegas, Nevada/ Poster 11-136

Objective: Determine the efficacy and safety of a pharmacist-driven adjusted body weight protocol for therapeutic intravenous (IV) heparin dosing in patients of all weights in a community health system.

Master Of Biomedical Sciences, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.

Insight - January 2019, Dugoni School Of Dentistry

Insight

Whether you are involved in clinical research, biomedical research, the scholarship of teaching and learning, improvement of the health care system, or professional partnerships that advance the field, we aim to spotlight the work of people at the Dugoni School.

Automobile Restraint Use Among Patients In Motor Vehicle Crashes: Factors Associated With Noncompliance, Ashley A. Brent

Scholarship in Medicine - All Papers

Despite the 1968 U.S. law requiring that all vehicles have seat belts in every seat, many drivers and passengers choose not to use them. This is an important healthcare issue when the there is an estimated $917 billion spent annually on hospital services due to noncompliance with seat belt use.1 Previous literature has demonstrated that patients who are noncompliant with seatbelts are not only “more likely to use more hospital resources because they are more severely injured”, but also less likely to have health insurance, thus incurring more debt for the hospitals serving them¹. Conversely, restraint compliance has …

Implementing The Summer Food Service Program Within The Healthcare Setting, Laura M. Plencner, Margo Quiriconi, Sarah Sentmore, Molly Krager

Posters

The Summer Food Service Program was established to ensure that children continue to receive adequate nutrition while school is out. This poster describes how the program was implemented in the Children's Mercy Kansas City healthcare system from 2016-2018.

Dental Practice Success Vol. 5 No. 4, American Dental Association, Publishing Division

Dental Practice Success

No abstract provided.

Review Of Literatures: Importance Of Vitamin D In Dentistry, Wareeratn Chengprapakorn

Chulalongkorn University Dental Journal

This article is aimed to review of literatures on vitamin D roles in overall health and its effects in dentistry, particularly, periodontal disease, orthodontics tooth movement, dental implant osseointegration and also osteonecrosis of the jaw. On account of new insights of vitamin D implication in immune response. This article will also focus on vitamin D effects on oral response to various dental procedures.

Microtensile Bond Strength Between Zirconia Ceramics To Resin Composite Using Different Resin Cements, Putsadee Srisomboonkamon, Prarom Salimee

Chulalongkorn University Dental Journal

Background/Objective: This study aimed to evaluate the microtensile bond strength (MTBS) of three zirconia ceramics from different manufacturers bonded to resin composite using three different resin cements. Materials and methods: Three fully-sintered zirconia ceramic blocks (5x5x10 mm) from Katana (Nuvodent, Japan), Lava (3M ESPE, Germany) and Cercon (Degudent, Germany) were fabricated and bonded to resin composite blocks (Filtek Z250, 3M ESPE, USA) with the same size using one of the three resin cements : Panavia F 2.0 (Kuraray, USA), Superbond C&B (Sun Medical, Japan) and RelyX Unicem (3M ESPE, USA). After 24 h, each block was cut under water coolant …

Fracture Resistance Of Endodontically Treated Maxillary Premolars Restored With Lithium Disilicate Restorations Using Three Different Retentive Techniques, Pakwan Varapongsittikul, Top Chitkraisorn, Nichamon Chaianant, Terawat Tosiriwatanapong, Boonsong Prateepsawangwong

Chulalongkorn University Dental Journal

To compare fracture resistance of endodontically treated maxillary premolars restored with ceramic restorations using three retentive techniques. Forty maxillary premolars were randomly selected as a control (Group 1), composite core/crown (Group 2), fiber-reinforced composite post/ composite core/crown (Group 3) and endocrown (Group 4). All restorations were thermo-cycled and subjected to vertical loading. Fracture load and fracture modes were analyzed. The results showed that Group 3 recorded a significantly highest fracture load (2304 ± 737 N). Pairwise comparisons showed no significant difference between Group 2 (1229 ± 303 N) and group 4 (1609 ± 395 N). Type of coronal-radicular retention was …

Comparison Of Resistance To Sliding In Posterior Units With Various Angulations Of Molar Tubes, Pornhathai Liewsaitong, Paiboon Techalertpaisarn

Chulalongkorn University Dental Journal

Background/objectives This study aimed to investigate the effect of one or two brackets on orthodontic frictional forces and to compare frictional forces of posterior segments when a molar tube had different degrees of tipping. Materials and Methods Five different types of posterior segment templates with six templates per type were constructed. Templates A and B had one and two brackets with an untipped tube, respectively. Templates C, D, and E had two brackets and a 3°, 6° or 9° tipped tube. Each template was coupled with 0.016″ x 0.022″ stainless steel wire and ligated with elastomeric ligatures. Static frictions were …

The Outcome Of Endodontic Treatment Performed By Dental Students: A Retrospective Study, Phonphanit Sivavetpikul, Kessiri Wisithphrom, Peraya Puapichartdumrong

Chulalongkorn University Dental Journal

Background/Objectives: The objectives of this study were to evaluate the success and failure rates as well as factors influencing the outcome of initial endodontic treatment performed by dental students at the Faculty of Dentistry, Naresuan University, Thailand, from 2010 to 2015. Materials and Methods: Data from the treatment records, clinical signs and symptoms, and radiographic records of 213 endodontically treated anterior teeth and premolar were collected and evaluated. Digital periapical radiographs obtained at pre-operation and the last follow-up period were interpreted independently by two examiners via Periapical index (PAI) score. Treatment outcome was evaluated as success or failure based on …

The Cura Personalis Of Healthcare Delivery: Ethical Reflections On Internal Medicine, Peter A. Depergola Ii

Journal of Health Ethics

In this essay, the author explores the meaning of care for the whole person, and underscores the mission of compassion as being willing to meet patients at their suffering point.

Managing Endings In The Beginning: Ethical Reflections On Neonatal Intensive Care, Peter A. Depergola Ii

Journal of Health Ethics

In this essay, the author examines the difficult task of determining quality of life for seriously-ill newborns, and highlights the narrative vitalism so often characteristic of those forced to make end-of-life decisions on behalf of those whose lives have just begun.

Dignity And The Life Worth Living: Ethical Reflections On Pediatric Intensive Care, Peter A. Depergola Ii

Journal of Health Ethics

In this essay, the author navigates the terrain of proxy decision making, and uncovers the hidden tendency of some clinicians to reduce quality of life to physical capability.

The Moral Obligation Of Bearing One Another’S Burdens: Ethical Reflections On Surgical Intensive Care, Peter A. Depergola Ii

Journal of Health Ethics

In this essay, the author analyzes the nature of curing and healing, and offers practical steps for managing families who request medically contraindicated interventions.

Healing Without Curing: Ethical Reflections On Palliative Care Medicine, Peter A. Depergola Ii

Journal of Health Ethics

In this essay, the author evaluates the nature of hope in the chronically ill, and emphasizes the many lessons dying individuals can teach us about living.

The Truths That Make Us Free: Ethical Reflections On Reproductive Endocrinology, Peter A. Depergola Ii

Journal of Health Ethics

In this essay, the author surveys the concept of therapeutic privilege, and addresses the temptation to respond to biographical questions with biological answers in the context of personal meaning-making.

The Morality Of Medical Miracles: Ethical Reflections On Pediatric Oncology, Peter A. Depergola Ii

Journal of Health Ethics

In this essay, the author investigates the practical ethics of miraculous healings, and proposes a four-step approach for working with parents who, for religious reasons, refuse life-saving treatment for children.

Informed About Informed Consent: A Qualitative Study Of Ethics Education, Rocksheng Zhong, John K. Northrop, Puneet K.C. Sahota, Henry B. Glick, Anthony L. Rostain

Journal of Health Ethics

Informed consent is a foundational concept in modern medicine. Despite physicians’ ethical and legal obligations to obtain informed consent, no standard curriculum exists to teach residents relevant knowledge and skills. This paper presents a qualitative study of residents at one academic medical center. The authors conducted focus groups with trainees in the Departments of Internal Medicine, Emergency Medicine, and Ob/Gyn and analyzed their responses using rigorous qualitative methods. Four themes emerged: First, participants agreed that informed consent and decision-making capacity were relevant in many clinical situations. Second, participants varied widely in their understandings of consent. Third, current resident training was …

Fake Medical News: The Ethics And Dangers Of Health Product Advertising Disguised As Real News, George A. Gellert

Journal of Health Ethics

Leading national newspapers in the US, challenged financially by the transition from paper to electronic media, are allowing drug and medical product advertisers to format their advertisements to appear like actual, authentic news articles. This news mimicry is intended to deceive consumers, and often makes claims of clinical efficacy and safety that are not evidence based and substantiated. An example of such an advertisement is presented and the clinical implications are considered, including recommendations to public health leadership organizations.

Hippocratic Values In An Era Of Nuclear Asymmetry: Should U.S. Public Health Prepare For Nuclear War With North Korea?, George A. Gellert

Journal of Health Ethics

Objectives: Advancements in North Korean nuclear weapons have heightened tensions and increased risk for nuclear war. U.S. public health agencies are investing resources in nuclear attack preparation. Analyses assess the impact and value of existing protective public health strategies for limited nuclear exchange.

Methods: Projections of fatality/injury from a North Korean nuclear strike within North Asia and explosive impact mapping are used to assess the potential impact of an attack on major U.S. urban centers.

Results: A nuclear strike on the 20 largest U.S. urban centers would place 38.1% of Americans at risk. With 1-3 missiles of 250 kiloton yield …

Intermittent Fasting In Weight Management, Alyse Engen

Physician Assistant Scholarly Project Posters

Obesity is associated with a variety of medical conditions that adversely affect metabolic and cardiovascular health. In order for health care providers to adequately educate and promote weight management, they need to be aware of the various dietary regimens and the efficacy and adverse effects associated with each. This literature review assesses the efficacy, metabolic benefits, and cardiovascular benefits of both intermittent energy restriction and continuous energy restriction from ten articles found on various databases within the past five years. The findings indicate that although not proven superior or inferior, intermittent energy restriction provides statistically similar results to continuous energy …

Comparing Rates Of Macrosomia And Neonatal Hypoglycemia Of Differing Treatment Modalities Of Gestational Diabetes Mellitus, Ashleigh Milbrath

Physician Assistant Scholarly Project Posters

Gestational diabetes mellitus (GDM) is a known potential complication that can occur during pregnancy. Unmanaged GDM can result in maternal hyperglycemia, which can cause increased neonatal complications, two of which are macrosomia and neonatal hypoglycemia. To prevent maternal hyperglycemia, treatment of GDM typically begins with dietary changes, home glucose monitoring, increased exercise patterns and other lifestyle modifications. However, if maternal hyperglycemia persists after two weeks of maternal lifestyle modifications, there are not current best practice guidelines established for the treatment of GDM. Historically, subcutaneous multiple daily dosed insulin (MDI) has been the gold standard for treatment after lifestyle modification. However, …

The Impact Of Shift Work On Health And Wellbeing, Stephanie Gagelin

Physician Assistant Scholarly Project Posters

Many of today’s industries require workers to perform shift work (typically during 1600-0700). If workers are awake during this time period, circadian misalignment occurs. This scholarly project uses research studies and metaanalyses to provide information about increased health risks associated with circadian misalignment, focusing on the categories of glucose metabolism, cardiovascular system, carcinogenesis, and mental health and acuity.

• Shift work has been found to increase BMI and waist circumference of employees, as well as increase blood glucose levels to “prediabetic” levels in previously euglycemic individuals.

• Shift work has been proven to increase high-sensitivity C-reactive protein (hs-CRP), an acute …

Is A Varicocelectomy Beneficial In The Era Of Assisted Reproductive Technologies?, Chukwuka Oscar Nnoli

Physician Assistant Scholarly Project Posters

Clinical varicoceles are the most frequent physical finding associated with infertile men and impaired semen parameters. There is evidence that suggests varicocele repair improves semen parameter and increases the chances of natural pregnancy. Today, varicocele repair is often combined with assisted reproductive techniques (ART) such as intrauterine insemination (IUI), in Vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI). In this literature review, data examining whether varicocelectomy before ART leads to improved pregnancy outcomes is reviewed. Current data suggest that there is a significant clinical benefit when correcting a varicocele in oligospermic men before IVF/ICSI. Similarly, men with non-obstructive azoospermia also …

Platelets To The Rescue? A Literature Review Of The Safety And Efficacy Of Platelet Rich Plasma For Symptomatic Osteoarthritis Of The Knee, Timothy Simonich

Physician Assistant Scholarly Project Posters

Osteoarthritis of the knee is one of the most common joint disorders in the United States with rising prevalence due to obesity and an aging population. Regarding non surgical approaches to management, there has been growing interest in the use of intra articular injections with Platelet Rich Plasma (PRP).