Medicine and Health Sciences Commons^™

Cam Impingement In A Collegiate Male Soccer Player With Bilateral Arthroscopic Labral Repair, Nayun Ahn

UNO Student Research and Creative Activity Fair

Cam impingement in a collegiate male soccer player with the bilateral arthroscopic labral repair.

To demonstrate cam impingement and recurrent cam deformity caused by femoroacetabular impingement after bilateral arthroscopic labral repair in a collegiate male soccer player. Cam impingement is caused by deformities of the femoral head. The deformity is generated due to overuse and high shear stress on the femoral head leading to restricted hip ROM by grinding the articular cartilage. It is typically detected in young, active male populations playing high-impact sports. In this case, one NCAA Division 1 soccer midfielder reported the recurrent cam impingement after he …

A Delayed Diagnosis Of Tarsometatarsal Ligament (Lisfranc) Sprain In A Female College Soccer Athlete And Foot Rehabilitation, Boyoung Park

UNO Student Research and Creative Activity Fair

A Delayed Diagnosis of Tarsometatarsal Ligament (Lisfranc) Sprain in a Female College Soccer Athlete and Foot Rehabilitation

Park B*, Nicola M*, Wilkins S*: *University of Nebraska at Omaha, Omaha, NE

Objective: To emphasize the importance of the correct treatment protocol and the proper rehabilitation exercises based on the patient’s injury condition and healing process. Background: A 22-year-old female division I soccer athlete underwent tarsometatarsal ligament repair to stabilize midfoot. The patient started feeling pain in the dorsal aspect of her left 1st and 2nd metatarsals at the beginning of the season, however, she reported no specific mechanism of injury …

Developing A Footswitch Device To Assess The Likelihood Of Falls In At-Risk Populations, Arash Mohammadzadeh Gonabadi

UNO Student Research and Creative Activity Fair

Falls are one of the major cause of injuries, reduced functioning and even mortality in older adults. Most of the falls occur during walking, so considering the mechanics of gait during walking can provide insight to identify the risk of fall in this population. A component of walking mechanics associated with falling in the elderly is gait variability (i.e. the inherent natural fluctuations between strides). Healthy states are associated with an optimal level of movement variability reflecting the adaptability of the underlying control system, while pathological gait can be either too regular, or periodic, or too random and disordered. In …

Venous Thoracic Outlet Syndrome With Paget-Schroetter’S Syndrome In A Male Collegiate Baseball Player, Jaeho Jang

UNO Student Research and Creative Activity Fair

A NCAA Division I baseball middle infielder complained of discomfort in his right upper extremity. He reported no specific mechanism of injury. He had a history of right elbow fracture at age eight with joint displacement. However, no other previous injury to his upper extremity was reported. He did not feel any pain or abnormal sensations while exercising, but noted some discomfort in the right arm, shoulder and pectoral muscles afterward. The evaluating athletic trainer also noted obvious swelling and discoloration of the right arm, bilaterally different temperature, decreased radial pulse, and positive Roo’s and Adson’s Tests. The venous duplex …

Subthreshold Vibration Does Not Affect Walking Performance Of Transtibial Amputees, Charles Sloan

UNO Student Research and Creative Activity Fair

Ian Sloan , Jenny A. Kent, Shane R. Wurdeman, Adam L. Jacobsen, Kota Z. Takahashi, Nicholas Stergiou. Subthreshold vibration does not affect walking performance of transtibial amputees. Objective: To test the hypothesis that adding subthreshold vibrations to the thigh of the affected limb on amputees would allow for better control of the prosthesis. Setting: Biomechanics Research Building at UNO. Participants: 14 transtibial amputees (age range, 33-72y). Intervention: Applying subthreshold vibrations to thigh of affected limb for three different conditions; white noise signal, pink noise signal, and none. Outcome Measures: Step length, step width, and step …

Dynamic Stability Association With Cost Of Transport Is Different In Patients With Copd Compared To Healthy Controls, Farahnaz Fallah Tafti

UNO Student Research and Creative Activity Fair

Patients with chronic obstructive pulmonary disease (COPD), suffer from deficits in their functional performance besides their lung disease. In this situation, increased muscle activity is needed to provide safe walking patterns, stability while walking. This increase in muscle activity leads to increased metabolic cost, i.e., using more oxygen to complete the task. The main objective of this study is to investigate the relationship between walking stability and metabolic cost in patients with COPD in comparison with age-matched controls. Seventeen patients with COPD and 23 healthy controls walked on a treadmill at three different speeds: preferred, fast (+20% preferred) and slow …

Acute Subdural Hematoma In A High School Football Player Requiring Emergent Decompressive Craniecromy, Christine Center

UNO Student Research and Creative Activity Fair

The purpose of this report is to present the case of a high school football player that was injured in a game causing an acute subdural hematoma (SDH). A SDH is a potential life-threatening arterial vessel bleed in the brain, causing increased intracranial pressure. The intervention used to treat the athlete was an emergent decompressive craniectomy. The uniqueness of the case is due to both rare pathology and treatment method used. The athlete had a positive outcome due to prompt on-field assessment, and advanced surgical treatments. Certified Athletic Trainers (ATC) should know how to recognize symptoms of traumatic brain injury, …

Can The Scale-Free Networks, Improve The Prediction Of Pertussis Infection Rates?, Kimia Ameri

UNO Student Research and Creative Activity Fair

Whooping cough is a highly contagious disease with randomness pattern of infection. Outbreaks of whooping cough have increased over the past few years and has drawn the attention of health care providers. Understanding the spread mechanisms of contagious disease is very important and timely. Extension of contagious disease depends on many complicated factors including pathogen and host environment, exposed population and their activities. In this work, we try to find best prediction for the exposed population. A new SEIR model based on network (NB-SEIR) proposed to improve the accuracy of prediction for number of infected individuals. For this purpose, the …

Overall Wellness Of First Generation College Student-Athletes, Shane Warehime

UNO Student Research and Creative Activity Fair

The present study examined the overall wellness of first-generation student-athletes (FGSA) in comparison to non-first generation student-athletes (non-FGSA),first-generation college students (FGCS), and non-first generation college students (non-FGCS). Overall wellness was assessed using the Five-Factor WellnessInventory. Non-FGSA scored significantly higher than non-FGCS in overall wellness and life satisfaction. Non-FGSA and FGSA scored significantly higher than non-FGCS and FGCS in the physical self subscale (i.e., diet, exercise). In sum, athletics may play an important role in the wellness of student-athletes, which could be enough to mitigate any challenges that first-generation college students face.

Follow My Voice: The Future Of Phr Authentication, Jeanette M. Rose, Ryan Schuetzler, John R. Windle, Ann L. Fruhling

UNO Student Research and Creative Activity Fair

The current electronic personal health record (PHR) has low patient adoption [1]. Increasing use and adoption of the PHR will improve patient-centered care. Users often have difficulty remembering passwords or share them, giving multiple people access to one account.

Utilizing biometrics for authentication is becoming more common in our daily lives – think of the fingerprint sensor on a smartphone or retina scanners at high security corporations. The quickly evolving technology that runs our lives calls for incorporating biometric authentication into more systems. Using biometric authentication can ensure that passwords would not need to be remembered and that only the …

Impact Of Real World Environments On Movement Variability, Matt Harrison

UNO Student Research and Creative Activity Fair

Osteoarthritis; OA for short, is the most common form of arthritis and is one of the leading causes of disability. OA is the progressive wearing down of the cartilage covering bones and joints. For those with end stage knee OA, a total knee arthroplasty, or replacement, is the standard treatment with more than 700,000 TKA’s performed annually. While pain is improved in general, the functional performance and activity levels of the joint often do not return to those of healthy individuals. To understand the long-term consequences of poor function post-TKA, we need data that characterizes an individual’s real-world movement and …

Supervised Walking Exercise Therapy Improves Gait Biomechanics In Patients With Peripheral Artery Disease, Anthony Arellano, Sara A. Myers, Iraklis Pipinos, Ben Senderling, Molly Schieber, Jason Johanning, Cassidy Berlin, Holly Despiegelaere

UNO Student Research and Creative Activity Fair

Peripheral artery disease (PAD) is commonly caused by atherosclerotic build-up of plaque within the peripheral arteries, affecting the blood flow to the legs. The most common presentation of PAD is intermittent claudication; a condition in which when the patient walks the metabolic demands of the lower limbs exceed the limited supply of blood, causing exercise- induced discomfort and decreased walking ability. Walking exercise is the first line of treatment in patients with claudication with the best results achieved in patients undergoing supervised exercise therapy for at least three months. Supervised walking exercise results in increased maximum walking distances comparable to …

Epigenetic Modifiers Promote Mitochondrial Biogenesis And Oxidative Metabolism Leading To Enhanced Differentiation Of Neuroprogenitor Cells., Martine Uittenbogaard, Christine A Brantner, Anne Chiaramello

Anatomy and Regenerative Biology Faculty Publications

During neural development, epigenetic modulation of chromatin acetylation is part of a dynamic, sequential and critical process to steer the fate of multipotent neural progenitors toward a specific lineage. Pan-HDAC inhibitors (HDCis) trigger neuronal differentiation by generating an "acetylation" signature and promoting the expression of neurogenic bHLH transcription factors. Our studies and others have revealed a link between neuronal differentiation and increase of mitochondrial mass. However, the neuronal regulation of mitochondrial biogenesis has remained largely unexplored. Here, we show that the HDACi, sodium butyrate (NaBt), promotes mitochondrial biogenesis via the NRF-1/Tfam axis in embryonic hippocampal progenitor cells and neuroprogenitor-like PC12-NeuroD6 …

Rare Case Of Diffuse Spinal Arachnoiditis Following A Complicated Vertebral Artery Dissection, Elias Atallah, Md, Sophia Dang, Sage Rahm, Nohra Chalouhi, Md, Stavropoula Tjoumakaris Md, Robert H. Rosenwasswer Md, Pascal Jabbour Md

Department of Neurosurgery Posters

Spinal arachnoiditis (SA) is an extremely rare and delayed complication of intracranial subarachnoid hemorrhage (SAH). SA is an inflammatory process leading to chronic fibrosis of the spinal cord. Possible pathophysiology is a two-staged disease of initial inflammatory reaction secondary to SAH, followed by a “free interval phase” prior to delayed adhesive phase (i.e. SA). The clinical course can be complicated and is the cause of major morbidity.

Reprogrammed Lipid Metabolism In Bladder Cancer With Cisplatin Resistance., Min Young Lee, Austin Yeon, Muhammad Shahid, Eunho Cho, Vikram Sairam, Robert Figlin, Khae-Hwan Kim, Jayoung Kim

Articles, Abstracts, and Reports

Due to its tendency to recur and acquire chemoresistance quickly, bladder cancer (BC) remains to be an elusive and difficult disease. Patients with recurrent and chemoresistant BC have an extremely poor prognosis. One possible approach that may provide insightful and valuable information regarding resistance mechanisms is looking into the lipid metabolism of BC cells. Metabolism of lipids is essential for cancer cells and is associated with the regulation of a variety of key cellular processes and functions. This study conducted a comparative lipidomic profiling of two isogenic human T24 bladder cancer cell lines, one of which is clinically characterized as …

Teaching The Principles Of Pediatric Critical Care To Non-Intensivists In Resource Limited Settings: Challenges And Opportunities, Michael F. Canarie, Asha N. Shenoi

Pediatrics Faculty Publications

No abstract provided.

Enhancing Clot Properties Through Fibrin-Specific Self-Cross-Linked Peg Side-Chain Microgels, Nicole Welsch, Ashley C. Brown, Thomas H. Barker, L. Andrew Lyon

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Excessive bleeding and resulting complications are a major cause of death in both trauma and surgical settings. Recently, there have been a number of investigations into the design of synthetic hemostatic agents with platelet-mimicking activity to effectively treat patients suffering from severe hemorrhage. We developed platelet-like particles from microgels composed of polymers carrying polyethylene glycol (PEG) side-chains and fibrin-targeting single domain variable fragment antibodies (PEG-PLPs). Comparable to natural platelets, PEG-PLPs were found to enhance the fibrin network formation in vitro through strong adhesion to the emerging fibrin clot and physical, non-covalent cross-linking of nascent fibrin fibers. Furthermore, the mechanical reinforcement …

Trapped As A Group, Escape As A Team: Applying Gamification To Incorporate Team-Building Skills Through An 'Escape Room' Experience, Xiao Chi Zhang, Hyunjoo Lee, Carlos Rodriguez, Joshua Rudner, Teresa M Chan, Dimitrios Papanagnou

Department of Emergency Medicine Faculty Papers

Teamwork, a skill critical for quality patient care, is recognized as a core competency by the Accreditation Council for Graduate Medical Education (ACGME). To date, there is no consensus on how to effectively teach these skills in a forum that engages learners, immerses members in life-like activities, and builds both trust and rapport. Recreational 'Escape Rooms' have gained popularity in creating a life-like environment that rewards players for working together, solving puzzles, and completing successions of mind-bending tasks in order to effectively 'escape the room' in the time allotted. In this regard, escape rooms share many parallels with the multitasking …

Cortical Thinning And Neuropsychiatric Outcomes In Children Exposed To Prenatal Adversity: A Role For Placental Crh?, Curt A. Sandman, Megan M. Curran, Elyssia Poggi Davis, Laura M. Glynn, Kevin Head, Tallie Z. Baram

Psychology Faculty Articles and Research

Exposure to early life adversity may disrupt the development and maturation of neurons and brain circuits, which, in turn, underlie neurodevelopment and mental illnesses. During fetal life, maternal adversity is conveyed to the developing brain via several molecular signals, including the stress hormone corticotropin releasing hormone (CRH). Employing a large well characterized prospective cohort, we find that fetal exposure to placental-origin CRH levels predicts structural and functional brain outcomes in children. Specifically, elevated placental CRH levels portend thinning of selective cortical regions of exposed individuals, with commensurate cognitive and emotional deficits. Notably, the relations of placental-origin CRH to cortical thinning …

The Best News For The Huntington's Disease Community Since The Discovery Of The Gene: Ionis Trial Data Revealed, Roche Confirms Jump To Phase 3, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.

Impact Of Supplemental Oxygen On Obstructive Sleep Apnea Of Infants, Piyush Das, R Kashyap, S Kotagal

Articles

Abstract: Treatment options may be limited for infants with obstructive sleep apnea when there is no surgically correctable upper airway lesion. We therefore evaluated, retrospectively, the efficacy of low-flow oxygen as a therapeutic option for infant obstructive sleep apnea. We reviewed the medical charts of 23 infants who had undergone a therapeutic trial of low-flow oxygen during polysomnography. Split-night polysomnography was used in 21/23 subjects while 2/23 had undergone two separate, full-night polysomnography sleep architecture and respiratory findings on the baseline polysomnogram segment that was obtained in room air were compared with the segment on low-flow oxygen (0.25–1 L/min). Wilcoxon …

Guide Lines Vol. I, Issue 13 - March 2018, College Of Health And Human Services

GUIDE Lines

Periodic Newsletter of the Governors State University - University of Illinois, Chicago - Disparities Education Cancer research training and education project (The GUIDE Project).

Healthnet News V.33:No.2 March-April 2018, Wendy Urciuoli

Articles - Patient Care

Linking Connecticut Patients and Families to Reliable Health Information

The Effects Of Contralateral Exercise On Patient Pain And Range Of Motion, Smokey Fermin, Lindsay Warren, Sarah Beene, David Wetzel

Health Sciences Faculty Scholarship

Clinicians are commonly tasked with treating patients suffering from range of motion (ROM) deficits, pain, or both. Treatment options intended to increase ROM, decrease pain and restore function are vast. Often interventions are used that focus on a singular symptom location (e.g., stretching and joint mobilizations) although a long-standing call exists to utilize global approaches to treating dysfunction. This review was conducted to determine whether evidence exists to support the use of contralateral exercise (CE)to treatROM deficits or pain.

Primary Care-Related Emergency Department Use, Tiffany Wetz

Theses & Dissertations

Primary care-related emergency department use has become a focal point in the United States considering health reform and changes made to the delivery model and reimbursement mechanisms. Emergency departments serve as critical access points within the United States delivery system because important medical resources are made available for all members within the community. However, a gap in the literature exists due to a lack of consensus regarding factors that influence emergency department use for primary care-related health needs. The purpose of this study was to understand the relationship between demographic, social, economic, geographic, and need factors that influenced use of …

The Santa Clara, 2018-03-01, Santa Clara University

The Santa Clara

No abstract provided.

The Functional Specialties: A Workshop On Applying Lonergan, Praxis Program Of The Advanced Seminar On Mission, Seton Hall University

Praxis Conference and Workshop Proceedings

These are the proceedings of the Praxis Program of the Advanced Seminar on Mission’s third annual summer workshop which was held in Trieste, Italy in July 2017. It focused on the application of Bernard Lonergan’s Functional Specialties to the work of the Seton Hall University faculty participants. The workshop was jointly sponsored by the Center for Vocation and Servant Leadership and the Center for Catholic Studies, and co-sponsored by Boston College, the Jacques Maritain Institute and the University of Trieste.

Tumorigenic Proteins Upregulated In The Mycn-Amplified Imr-32 Human Neuroblastoma Cells Promote Proliferation And Migration., Hayat Zaatiti, Jad Abdallah, Zeina Nasr, George Khazen, Anthony Sandler, Tamara J Abou-Antoun

Surgery Faculty Publications

Childhood neuroblastoma is one of the most common types of extra-cranial cancer affecting children with a clinical spectrum ranging from spontaneous regression to malignant and fatal progression. In order to improve the clinical outcomes of children with high-risk neuroblastoma, it is crucial to understand the tumorigenic mechanisms that govern its malignant behaviors. MYCN proto-oncogene, bHLH transcription factor (MYCN) amplification has been implicated in the malignant, treatment-evasive nature of aggressive, high-risk neuroblastoma. In this study, we used a SILAC approach to compare the proteomic signatures of MYCN-amplified IMR-32 and non-MYCN-amplified SK-N-SH human neuroblastoma cells. Tumorigenic proteins, including fatty-acid binding protein 5 …

The Peripheral Vascular Intervention (Pvi)-Lower Extremity Structured Report: A Tool For Physician Reporting Data Elements For The National Cardiovascular Data Registry (Ncdr ® ) Pvi Registry ™, Emily Keltner Bs, Ma, Brenda Springer, T. Eric White Md

Parkview Heart Institute

Background

The American College of Cardiology (ACC)/ National Cardiovascular Data Registry (NCDR®) Peripheral Vascular Intervention (PVI) Registry™ relies on thorough data collection to give registry participants a way to measure and improve the quality of care they provide to their patients. The majority of the data being collected in the PVI lower extremity procedures comes directly from the Interventional Cardiologist’s procedural report. There were three different reports from five physicians. The Interventional Cardiologist Group meets monthly to discuss cases and other pertinent information to the group. The members of this group include the Interventional Cardiologists, Parkview Heart Institute’s Chief Operating …

Improving Eukaryotic Genome Annotation Using Single Molecule Mrna Sequencing., Vincent Magrini, Xin Gao, Bruce A Rosa, Sean Mcgrath, Xu Zhang, Kymberlie Hallsworth-Pepin, John Martin, John Hawdon, Richard K Wilson, Makedonka Mitreva

Microbiology, Immunology, and Tropical Medicine Faculty Publications

BACKGROUND: The advantages of Pacific Biosciences (PacBio) single-molecule real-time (SMRT) technology include long reads, low systematic bias, and high consensus read accuracy. Here we use these attributes to improve on the genome annotation of the parasitic hookworm Ancylostoma ceylanicum using PacBio RNA-Seq.

RESULTS: We sequenced 192,888 circular consensus sequences (CCS) derived from cDNAs generated using the CloneTech SMARTer system. These SMARTer-SMRT libraries were normalized and size-selected providing a robust population of expressed structural genes for subsequent genome annotation. We demonstrate PacBio mRNA sequences based genome annotation improvement, compared to genome annotation using conventional sequencing-by-synthesis alone, by identifying 1609 (9.2%) new …