Medicine and Health Sciences Commons^™

What's Happening: March 19, 2018, Maine Medical Center

What's Happening

No abstract provided.

Fenestration Of The Proximal Left Ovarian Vein., Mayank Patel, Joe Iwanaga, Rod J Oskouian, R Shane Tubbs

Articles, Abstracts, and Reports

A fenestration in the left ovarian vein was found in a fresh-frozen female cadaver. The opening did not have any vessels or additional anatomical structures passing through it. The ovarian vein is also referred to as the female gonadal vein. This type of anatomical variation is clinically relevant in procedures that deal with the manipulation of the gonadal veins, specifically conditions such as ovarian vein thrombosis, ovarian vein stenosis, and pelvic congestion syndrome.

The Current Trend Of The Translational Research Paradigm., Paul J Choi, R Shane Tubbs, Rod J Oskouian

Articles, Abstracts, and Reports

The translational research paradigm is a process of discovering basic science concepts and applying the knowledge in clinical practice, aiming to improve patient care. The stages involved in the paradigm form a complex network of shared knowledge amongst research collaborators, including patients. This nature of the paradigm allows those involved to work together effectively. However, the translational research paradigm is often overlooked by many scientists, educators, and research institutions. Hence, a large amount of comprehensive and hugely invested research projects fail to make a scientific impact. We aim to outline and describe this paradigm in order to aid in the …

Specificity In Sociality: Mice And Prairie Voles Exhibit Different Patterns Of Peer Affiliation, Annaliese K. Beery, Jennifer D. Christensen, Nicole S. Lee, Katrina L. Blandino

Psychology: Faculty Publications

Social behavior is often described as a unified concept, but highly social (group- living) species exhibit distinct social structures and may make different social decisions. Prairie voles (Microtus ochrogaster) are socially monogamous rodents that often reside in extended family groups, and exhibit robust preferences for familiar social partners (same- and opposite-sex) during extended choice tests, although short-term preferences are not known. Mice (Mus musculus) are gregarious and colonial, but in brief laboratory tests of social preference they typically prefer social novelty. This preference for novel vs. familiar peers may represent a species-specific difference in social decision-making between mice and prairie …

Screening For Cancers In Males With Family History Of Breast And Ovarian Cancer, Amanda L. Schmieg

Nursing Capstones

No abstract provided.

Refleksi Otot Progresif Menurunkan Stres Keluarga Yang Merawat Pasien Gangguan Jiwa, Livana Ph, Novy Helena Catharina Daulima, Mustikasari Mustikasari

Jurnal Keperawatan Indonesia

Effect of progressive muscle relaxation to the level of family stress in caring for clients of mental disorders in Psiciatry Polyclinic Regional General Hospital Kendal. Mental disorders are not contagious disease that is public health problem, both in the world and in Indonesia. In kendal the number of mental disorders increase so increasing the level of family stress. The purpose of this study to identify the effect of progressive muscle relaxation on the level of family stress in caring for clients of mental disorders in Psiciatry Polyclinic Regional General Hospital Kendal. Quasi experiments research design pre-post test with control group …

04-10-2018 Notice Of Hsc Committee Mtg, Patrice Martin

HSC Committee (A subcommittee of the UNM Board of Regents)

No abstract provided.

Week Of March 19, 2018, New York Medical College

InTouch

• Match Day 2018: An Impressive Day for the School of Medicine Class of 2018
• Beis Yosef Synagogue Dedicated to Mr. Joseph Appleman
• Dedication Ceremony Honors the Memory of Rita F. Girolamo, M.D. '51
• Richard White, M.D., Ph.D., to Address 30th Annual Graduate Student Research Forum
• Department of Cell Biology and Anatomy Hosts Annual Research Forum
• Department of Public Health Seminar Addresses the Rohingya Crisis

Spsnet: Subpopulation-Sensitive Network-Based Analysis Of Heterogeneous Gene Expression Data., Abha Belorkar, Rajanikanth Vadigepalli, Limsoon Wong

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

BACKGROUND: Transcriptomic datasets often contain undeclared heterogeneity arising from biological variation such as diversity of disease subtypes, treatment subgroups, time-series gene expression, nested experimental conditions, as well as technical variation due to batch effects, platform differences in integrated meta-analyses, etc. However, current analysis approaches are primarily designed to handle comparisons between experimental conditions represented by homogeneous samples, thus precluding the discovery of underlying subphenotypes. Unsupervised methods for subtype identification are typically based on individual gene level analysis, which often result in irreproducible gene signatures for potential subtypes. Emerging methods to study heterogeneity have been largely developed in the context of …

The Value Of Mri In Distinguishing Subtypes Of Lipomatous Extremity Tumors Needs Reassessment In The Era Of Mdm2 And Cdk4 Testing, Sean Ryan, Julia Visgauss, David Kerr, Joshua Helmkamp, Nicholas Said, Emily Vinson, Patrick W. O'Donnell, Xuechan Li, Sin-Ho Jung, Diana Cardona, William Eward, Brian Brigman

Markey Cancer Center Faculty Publications

Introduction. Extremity lipomas and well-differentiated liposarcomas (WDLs) are difficult to distinguish on MR imaging. We sought to evaluate the accuracy of MRI interpretation using MDM2 amplification, via fluorescence in-situ hybridization (FISH), as the gold standard for pathologic diagnosis. Furthermore, we aimed to investigate the utility of a diagnostic formula proposed in the literature. Methods. We retrospectively collected 49 patients with lipomas or WDLs utilizing MDM2 for pathologic diagnosis. Four expert readers interpreted each patient's MRI independently and provided a diagnosis. Additionally, a formula based on imaging characteristics (i.e. tumor depth, diameter, presence of septa, and internal cystic change) …

Contributions Of Mean And Shape Of Blood Pressure Distribution To Worldwide Trends And Variations In Raised Blood Pressure: A Pooled Analysis Of 1018 Population-Based Measurement Studies With 88.6 Million Participants, Majid Ezzati, Bin Zhou, James Bentham, Mariachiara Di Cesare, Honor Bixby, Goodarz Danaei, Kaveh Hajifathalian, Cristina Taddei, Rodrigo M. Carrillo-Larco, Shirin Djalalinia, Shahab Khatibzadeh, Charles Lugero, Niloofar Peykari, Wan Zhu Zhang, James Bennett, Ver Bilano, Gretchen A. Stevens, Melanie J. Cowan, Leanne M. Riley, Zhengming Chen, Ian R. Hambleton, Rod T. Jackson, Andre Pascal Kengne, Young Ho Khang, Avula Laxmaiah, Jing Liu, Reza Malekzadeh, Hannelore K. Neuhauser, Maroje Sorić, Gregor Starc, Johan Sundström, Tara Coppinger, Janette Walton, Con Burns, Mark Woodward

Publications

Background: Change in the prevalence of raised blood pressure could be due to both shifts in the entire distribution of blood pressure (representing the combined effects of public health interventions and secular trends) and changes in its high-blood-pressure tail (representing successful clinical interventions to control blood pressure in the hypertensive population). Our aim was to quantify the contributions of these two phenomena to the worldwide trends in the prevalence of raised blood pressure. Methods: We pooled 1018 population-based studies with blood pressure measurements on 88.6 million participants from 1985 to 2016. We first calculated mean systolic blood pressure (SBP), mean …

Subclinical Atherosclerosis Vascular Evaluation (Save): Nurse Practitioner Barriers To And Facilitators Of Research Utilization Regarding Screening For Subclinical Atherosclerosis, Gina Pritchard

DNP Projects

The project identified factors affecting implementation of evidence-based non-invasive screening tests to identify early stage cardiovascular disease (CVD). The use of coronary artery calcium scores and carotid intima media thickness testing improves accuracy of risk stratification over risk factor scoring systems alone. The purpose of this project was to identify NP’s perceived barriers to and facilitators of utilization of evidence-based non-invasive CVD screening tests and to make recommendations for improvements in implementation. The SAVE project consisted of a cross-sectional survey of 64 nurse practitioners, recruited using a multi-pronged strategy, using Funk’s barriers instrument plus two additional qualitative questions regarding intent …

Terapi Kelompok Asertif Efektif Meningkatkan Kemampuan Asertif Dan Resiliensi Pada Remaja Di Smpn Padangpanjang, Rosa Fitri Amalia, Budi Anna Keliat

Jurnal Keperawatan Indonesia

The Effect of Assertive Group Therapy on Assertive and Resilience Ability of Adolescent in Padangpanjang Junior High School. Adolescent’s lack of ability in assertive behaviour causes deviant behaviour e.g. unable to express wishes, violate other people right and ask forcefully. One solution to overcome this is that assertive ability and resilience need to be improved through assertive group therapy. This study aims to find the effect of assertive group therapy on assertive ability and resilience of adolescents. Quasi Experimental Pre and Post-test with control group was used. Intervention has been performed to 42 participants while 42 others were as a …

Factors Affecting Quality Of Life For Children With Asthma, Sheri K. Carey, Crystal M. Edds-Mcafee, Valerie Martinez, Kathy Thornton, Antonio P. Gutierrez

Nursing: Faculty Presentations (1990-2022)

BACKGROUND: In the U.S., asthma is the most common chronic illness in children under 18 years. An exploration of asthma admission rates in emergency departments indicated this was also the case for Southeast Georgia. Despite the availability of effective asthma treatments and interventions, asthma continues to severely impact children’s health-related QOL. PURPOSE: This exploratory study sought to assess quality of life (QOL) issues facing children with asthma and their caregivers. Specifically, this study aimed to 1) Determine the baseline QOL in children with asthma and their parents/caregivers, & 2) Determine what factors affect QOL for children with asthma and their …

Medical School Watercooler Newsletter - March 18, 2018, Lindsey Lyle

Watercooler Newsletter

This is the March 18, 2018 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents Include:

• University of South Alabama Celebrates Giving Day
• Register Now: Oncology Outlook 2018
• April Med School Café – 'Medicine in Art'
• USA Residents Visit Theodore High School, Participate in Community Outreach Project

Approaches To Hypertension Management In Patients Over Eighty Years Old, Lillia Budd

Nursing Capstones

No abstract provided.

Exploring The Need Of Hpv Education Programs In Korean American Communities, Emilia Mondragón, Young-Me Lee

Grace Peterson Nursing Research Colloquium

Aim: 1) To identify cultural influences and other barriers affecting HPV vaccination decisions, 2) To identify educational methods that can deliver HPV related information to Korean American (KA) parents effectively

Background: Given significant concerns about HPV infection, lower immunization rates, and higher cervical cancer risks facing Korean Americans, it is imperative to better understand the barriers to vaccination. Currently, there is no HPV-focused education program that considers the linguistic and cultural barriers of the KA community. Additionally, there is a lack of effective educational content and methods available to reach KA parents.

Methods: An exploratory, qualitative design was conducted. Content …

Myo/Nog Cells Are Present In The Ciliary Processes, On The Zonule Of Zinn And Posterior Capsule Of The Lens Following Cataract Surgery, Jacquelyn Gerhart, Colleen Withers, Colby Gerhart, Liliana Werner, Nick Mamalis, Arturo Bravo Nuevo, Victoria Scheinfeld, Paul Fitzgerald, Robert Getts, Mindy George-Weinstein

PCOM Scholarly Works

Myo/Nog cells, named for their expression of MyoD and noggin, enter the eye during early stages of embryonic development. Their release of noggin is critical for normal morphogenesis of the lens and retina. Myo/Nog cells are also present in adult eyes. Single nucleated skeletal muscle cells designated as myofibroblasts arise from Myo/Nog cells in cultures of lens tissue. In this report we document the presence of Myo/Nog cells in the lens, ciliary body and on the zonule of Zinn in mice, rabbits and humans. Myo/Nog cells were rare in all three structures. Their prevalence increased in the lens and ciliary …

Preconception Counseling: Frequently Forgotten By Primary Care Providers Due To Multiple Barriers, Angela Magdaleno, Sandhya Venkataraman Do, Melissa M. Dion Md, Gretchen Perilli Md, Marc Vengrove Do, Facp

Department of Medicine

No abstract provided.

How Many Grays To Get To The Malfunction Of An Insulin Pump?, Angela Magdaleno, Gretchen Perilli Md, Bonnie Patek Do, Robert Schreiner Do, Marc Vengrove Do, Facp

Department of Medicine

No abstract provided.

Learning From Our Mothers: Examining The Role Of Intergenerational Knowledge Transfer In Advancing Gender Equity Among Sri Lankan Youth, Ruvani Fonseka, Samantha Hurst

Faculty Research, Scholarly, and Creative Activity

No abstract provided.

Investigating Ampk Signalling Regulation Of Autophagy In A Model Of Ovarian Tumour Dormancy, Jeremi Laski

Western Research Forum

Investigating AMPK signalling regulation of autophagy in a model of ovarian tumour dormancy

Jeremi Laski and Trevor G. Shepherd

Background:

Ovarian cancer is the most deadly gynecologic malignancy in women. A particular subset of this disease, epithelial ovarian cancer (EOC), is responsible for over 70% of all diagnosed ovarian cancer cases, yet the mechanisms governing disease progression are poorly understood. One of the unique hallmarks of EOC metastasis lies in the process of spheroid formation, whereby tumour cells aggregate into larger 3D structures. These EOC spheroids have been shown to be metabolically dormant, while concurrently up-regulating autophagy (cellular waste …

Multisensory Integration And Autistic Traits Using Non-Sociolinguistic Information, Sébastien A. Lauzon, Samantha E. Schulz, Zack I. Cohen, Ryan A. Stevenson

Western Research Forum

Background: Sensory processing issues are one of the most common complaints in autism spectrum disorder (ASD). One area of sensory difficulties in ASD that has been the focus of intense research in recent years is multisensory integration (MSI), or the ability to bind auditory and visual information into a single, unified percept. While integration of social or linguistic information is consistently shown to be an area of difficulty in ASD, results are less clear with simple, non-sociolinguistic stimuli. This study aims to address this ambiguity by determining whether MSI of non-sociolinguistic sensory information is related to traits and symptomatology …

Organizational Behaviour During Instability: A Critical Discourse Analysis Of Shared Mental Model Through Various Forms Of Acute Care Learning Using Mixed Methods, Adam Morse, Ryan Chan

Western Research Forum

Background: The purpose of this study is to better understand nurses' performance based on training processes. This will determine if group training will increase performance compared to independent training through a shared mental model in a contextual setting of unpredictability mediated by the effects of nurses’ perceptions of patient safety climate. A mixed methods study is conducted using critical discourse analysis of organizational documentation and semi-structured interviews to determine measures of contextual setting when identifying and treating sex trade workers.

Methods: Pragmatic study will analyze two groups of 125 nurses each determining the impact of group and individual …

Associated Factors Of Cam Use In Adults With Chronic Pain: A Scoping Review, Jessica Lachance

Western Research Forum

Background: Chronic pain is a multifaceted, complex disorder resulting in disability that poses a significant impact on the quality of life for those afflicted and serious effects on society and the health care system at large. Available conventional treatments for chronic pain are not fully effective, resulting in more people turning to Complementary and Alternative Medicine to manage it. This area encompasses any medical system or therapy that resides outside of the conventional medical treatments of a given society, for example: acupuncture, chiropractic, massage, or Traditional Chinese Medicine. One important direction of research in this area is to understand the …

Effects Of Mental Imagery Use On Anxiety, Confidence, Mental Well-Being, And Performance In Track And Field Athletes, Sarah J. Deck, Despina Kouali, Craig Hall Dr.

Western Research Forum

Background: Student athletes can experience a number of stressors above and beyond those of their classmates, one being competition anxiety in their specific sport, which is common among varsity athletes (Storch, Storch, Killiany, & Roberti, 2005). Unfortunately, the tools to help with the demands of their sport mentally are often overlooked by not only the athletes, but their coaches, teammates, and supporters. The purpose of the present study was to introduce imagery as a tool to help deal with competition anxiety (i.e., fear of failure), and to improve confidence, mental well-being, and performance.

Methods: Two female varsity level throwers ( …

A Chimeric Nucleobase - Phenylazo Derivative As An Intrinsic Nucleobase Quencher, Gyeongsu Park, Timothy Martin-Chan, Amer El Samm, Robert H.E. Hudson

Western Research Forum

Molecular beacons are important bioanalytical probes which are most often

constructed from a single-stranded oligonucleotide which has been labeled at

opposite termini with a fluorophore and a quencher. When the fluorophore and

quencher are in close proximity, no fluorescence is observed due to FRET

(Fluorescence Resonance Energy Transfer). DABCYL (4-dimethylaminoazobenzene-

4'-carboxylic acid) has been used as a quencher in the molecular beacon to absorbs

excitation energy from a fluorophore and to dissipate the energy as heat. However,

DABCYL is unable to form a base-pair and is conventionally placed as an overhanging

residue. This produces a derivative wherein the chromophore has …

Developing Novel Therapeutics For Bacterial Lung Infections, Brandon J. Baer, Ruud Veldhuizen, Cory Yamashita

Western Research Forum

Background: Bacterial lung infections are leading causes of death worldwide. Unfortunately, increasing resistance to antibiotics and the inflammation often accompanying these infections are leading to poor outcomes despite antibiotic intervention. Complicating treatment further, the tree-like branching structure of the lung makes drug delivery to distal sites of infection difficult. Our research aims to address these challenges by developing new therapeutics and new tools to improve and assess drug delivery, bacterial killing and inflammation. Our therapy combines host defense peptides, which have been shown to kill antibiotic-resistant bacteria and down regulate inflammation, with a pulmonary vehicle, exogenous surfactant, that can improve …

Head Injury Risk And Car Seat Use For Children In Collisions, Peyton A. Schroeder, M.J. Skhurm, D. Fraser, K. Mcclafferty

Western Research Forum

Background: Motor vehicle collisions (MVCs) are the leading cause of death for people under the age of 17 years. Almost 80% of rear seat motor vehicle passengers are children. Previous studies have shown that a large fraction of injuries to children in MVCs involved the head and chest. In this study, the hypothesis that children under the age of eight using a forward-facing child restraint system (FFCRS) will have more severe head injuries than children using any other type of restraints in an MVC was tested.

Methods: Several datasets obtained from Transport Canada and Level 1 Pediatric Trauma Centre emergency …

Perioperative Gait Analysis After Total Hip Arthroplasty: Does Outpatient Surgery Compromise Patient Outcomes?, Bryn O. Zomar, Susan W. Hunter, Dianne Bryant, Brent A. Lanting, James L. Howard

Western Research Forum

Background: There has been a continuing trend towards decreasing the length of hospital stay for patients undergoing total hip arthroplasty (THA). Outpatient procedures, discharging patients on the same day as surgery, have now become possible yet little research has been done to examine the impact this might have on patients during early recovery. We aimed to investigate the impact of discharge time on gait and patient-reported outcomes in the early post-operative period.

Methods: We measured gait velocity, stride length, single-limb support and single-limb support symmetry preoperatively, at discharge from the hospital, and two-, six- and 12-weeks postoperatively. Participants also completed …