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Articles 7921 - 7950 of 15442
Full-Text Articles in Medicine and Health Sciences
Preparing Nursing Students To Respond To Disasters: Faculty Perspectives, Melissa Jayne Freshwater
Preparing Nursing Students To Respond To Disasters: Faculty Perspectives, Melissa Jayne Freshwater
Dissertations
This mixed methods study explored emergency preparedness and disaster response in the concept-based learning curriculum adopted by the Alabama Community College System (ACCS) in 2016. The concept-based curriculum employs active learning in lieu of the traditional lecture-style teaching methods.
This study addressed the problem that educators may be unfamiliar with this content and are unsure how to present this material to students. The purpose of this study was to gain insight on teaching methodologies, to better prepare nursing students on this content.
Kolb’s 1984 Experiential Learning Theory was the framework that parallels closely with this curriculum. Kolb emphasizes four stages …
Comparison Of Different Temperatures On Bending Properties Of Six Niti Endodontic File Systems, Sukbum Yoo
Comparison Of Different Temperatures On Bending Properties Of Six Niti Endodontic File Systems, Sukbum Yoo
Master's Theses (2009 -)
Introduction: Manufacturers claim that modern NiTi files with proprietary heat treatment transform at higher temperatures, thus staying more martensite and being more resistant to cyclic fatigue and more flexible. There are some studies comparing the effect of body temperature and room temperature on cyclic fatigue of these newer NiTi files. However, there is not yet a study published for evaluating the relationship between bending properties of NiTi instruments and temperature following the ISO 3630-1 guideline. The objective of this study was to evaluate how temperature affects the bending properties of six different brands of NiTi rotary instruments with different transformation …
A Retrospective Analysis Of Patient Medical And Dental Treatment Histories, And Mronj-Related Events, Jon Irelan
A Retrospective Analysis Of Patient Medical And Dental Treatment Histories, And Mronj-Related Events, Jon Irelan
Master's Theses (2009 -)
With patient medical histories continuing to increase in complexity, dental professionals are faced with the task of delivering necessary care while respecting said medical history. Though advances have been made in combating osteopathies like osteoporosis and bone-related malignancies through medicinal intervention, these same medications can alter the bone’s ability to heal properly. The result of this inability to heal can be medication-related osteonecrosis of the jaw (MRONJ). The purpose of this study was to evaluate whether patients at risk for MRONJ treated at Marquette University School of Dentistry (MUSoD) demonstrated any complications following endodontic therapies associated with MRONJ. During the …
Factors Effecting Survival Of Teeth With Nonsurgical Root Canal Therapy Including A Multi-State Outcome Analysis, Alex Moore
Master's Theses (2009 -)
Objective: To study the factors effecting the survival of teeth with non-surgical root canal therapy (NS-RCT) and to compare the transitions between failure states for teeth treated with NS-RCT based on initial provider type. Methods: Insurance claims were analyzed for 438,487 initial NS-RCT procedures to determine the effect of provider type, patient age, tooth position, presence of post/core, and crown at 90 days on tooth survival. Kaplan Meier survival estimates were evaluated for 1, 3, 5, and 10 years and adjusted hazard ratios (aHR’s) were calculated. A multi-state model with six transitions was created using the ‘mstate’ R package. Results: …
The Famous Names Discrimination Task As A Biomarker Of Alzheimer's Disease Risk: An Erp Study, Elizabeth Rose Paitel
The Famous Names Discrimination Task As A Biomarker Of Alzheimer's Disease Risk: An Erp Study, Elizabeth Rose Paitel
Master's Theses (2009 -)
Current ERP research emphasizes age- and pathology-related declines in neural processing in the form of attenuated amplitudes and prolonged latencies. Notably, there is a gap in the ERP literature regarding neural processing trajectories in the time between healthy young adulthood and clinical MCI/AD samples. fMRI research, however, has demonstrated periods of increased, compensatory activation in healthy, cognitively intact APOE ɛ4 carriers both during resting state and event-related tasks (Bondi, Houston, Eyler, & Brown, 2005; Evans et al., 2014; Filippini et al., 2009; Rao et al., 2015), consistent with compensatory theories of cognitive aging (Cabeza, 2002; Park & Reuter-Lorenz, 2009; Reuter-Lorenz …
Investigation Of Reactive Oxygen Species Production In The Rat Lung Using Optical Imaging, Nina Friedly
Investigation Of Reactive Oxygen Species Production In The Rat Lung Using Optical Imaging, Nina Friedly
Master's Theses (2009 -)
Oxidative stress, the imbalance between production of oxidants or reactive oxygen species (ROS) and antioxidant activity, plays a key role in the pathogenesis of acute and chronic lung diseases. The objective of this thesis was to develop a robust protocol for measuring the rate of H2O2 production in isolated perfused rat lungs and to determine the cellular sources of that rate using Amplex Red (AR). For a given lung, AR (25 mM) along with horseradish peroxidase (5 U/ml) and ascorbate oxidase (1U/ml) were added to a perfusate reservoir that was recirculated through the lungs and sampled at 5 minute intervals …
Effect Of Emergence Profile Of A Single Implant Restoration On The Health Of Peri-Implant Soft Tissue, Waleed Nasir Asiri
Effect Of Emergence Profile Of A Single Implant Restoration On The Health Of Peri-Implant Soft Tissue, Waleed Nasir Asiri
Master's Theses (2009 -)
Purpose: The specific aims of this retrospective study were 1) to compare the emergence angle of a single implant crown (SIC) of the mandibular first molar to the emergence angle of the natural contralateral tooth, 2) to evaluate the effect of the emergence angle of SIC on the health of the peri-implant soft tissue and 3) to quantify an acceptable emergence angle among SIC. Materials and methods: Ten Marquette University School of Dentistry (MUSoD) patients were included in the study. Each patient was examined clinically and plaque index (PI), probing depth (PD), and bleeding on probing (BOP) measurements were gathered …
Effect Of Different Finish Line Designs On The Marginal And Internal Fit Of Metal Copings Made By Selective Laser Melting Technology, Adel Al Maaz
Master's Theses (2009 -)
Introduction: Marginal fit has been defined as the gap between the prepared tooth and the intaglio surface of the restoration. Internal gap is the perpendicular measurement from the internal surface of the casting to the axial wall of the preparation. Selective laser melting has been used for fabrication of metal copings such as Co-Cr base alloys and Au-Pt noble alloys. The purpose of this study was to determine the effect of different finish line designs on the marginal and internal fit of metal copings made from high noble, 25% noble and base alloys manufactured by SLM technology. Material and Methods: …
Using Video Self-Modeling To Improve Reading Fluency In School Aged Children With Specific Learning Disabilities, Chelsea Nicole Ollar
Using Video Self-Modeling To Improve Reading Fluency In School Aged Children With Specific Learning Disabilities, Chelsea Nicole Ollar
Theses and Dissertations
Effective reading interventions for students with specific learning disabilities (SLD) are needed. A multiprobe multiple baseline across participants design was used to evaluate the effects of a video self-modeling intervention (VSM) on reading fluency skills. The VSM interventions effects on self-efficacy were also measured. Four male middle school students with SLD watched a pre-recorded video of themselves reading a passage fluently and were then asked to read another passage. Words correct per minute (WCPM) and accuracy data were taken. Results showed that students read significantly more words correct when they watched themselves read the same passage they were about to …
Mud-Splattered Fundus, Roger Joel Welch, Xintong Li, Carol L. Shields
Mud-Splattered Fundus, Roger Joel Welch, Xintong Li, Carol L. Shields
Wills Eye Hospital Papers
No abstract provided.
The Effects Of A Social Communication Intervention On The Correct Production Of Emotion Words For Children With Language Impairment, Julia Vincent Hetherton
The Effects Of A Social Communication Intervention On The Correct Production Of Emotion Words For Children With Language Impairment, Julia Vincent Hetherton
Theses and Dissertations
Many school-age children with language impairment (LI) have difficulties with aspects of social and emotional learning. This study was structured to evaluate one aspect of the effectiveness of a social communication intervention, the appropriate production of emotion words. Four school-aged children with LI participated in 20 sessions of story-based intervention targeting understanding and usage of emotion-based words. Emotions targeted included the emotion word categories of happiness, sadness, anger, fear, surprise, and disgust. Because the knowledge of the emotion word categories varied from child to child, each child had different target words. The percentage of correct production of targeted emotion …
Pim-1 Kinase Phosphorylates Cardiac Troponin I And Regulates Cardiac Myofilament Function., Ni Zhu, Bing Yi, Zhifu Guo, Guanxin Zhang, Shengdong Huang, Yongwen Qin, Xianxian Zhao, Jianxin Sun
Pim-1 Kinase Phosphorylates Cardiac Troponin I And Regulates Cardiac Myofilament Function., Ni Zhu, Bing Yi, Zhifu Guo, Guanxin Zhang, Shengdong Huang, Yongwen Qin, Xianxian Zhao, Jianxin Sun
Center for Translational Medicine Faculty Papers
BACKGROUND/AIMS: Pim-1 is a serine/threonine kinase that is highly expressed in the heart, and exerts potent cardiac protective effects through enhancing survival, proliferation, and regeneration of cardiomyocytes. Its myocardial specific substrates, however, remain unknown. In the present study, we aim to investigate whether Pim-1 modulates myofilament activity through phosphorylation of cardiac troponin I (cTnI), a key component in regulating myofilament function in the heart.
METHODS: Coimmunoprecipitation and immunofluorescent assays were employed to investigate the interaction of Pim-1 with cTnI in cardiomyocytes. Biochemical, site directed mutagenesis, and mass spectrometric analyses were utilized to identify the phosphorylation sites of Pim1 in cTnI. …
Path2 Services Court: A Process Evaluation, Octavio Jimenez
Path2 Services Court: A Process Evaluation, Octavio Jimenez
Master's Projects
In 2014, the Santa Clara County Superior Court received a Substance Abuse and Mental Health Services Administration (SAMHSA) grant to improve the efficacy of the Juvenile Treatment Court (JTC) and Court for the Individualized Treatment of Adolescents (CITA) programs by streamlining the referral, screening, and court hearing processes. Receipt of the grant allowed the Superior Court to integrate JTC and CITA to establish the Progress Achieved Through Hope and Holistic Services (PATH2 Services) Court.
This research analyzed whether the Santa Clara County Superior Court successfully integrated the JTC and CITA programs when it established PATH2 Services. In addition it determined …
Improvements In Cultural Competence In Athletic Training And Rehabilitative Science Students Through Classroom Activities, Jason M. Denton, Shandra Esparza, David S. Fike, Jaime González
Improvements In Cultural Competence In Athletic Training And Rehabilitative Science Students Through Classroom Activities, Jason M. Denton, Shandra Esparza, David S. Fike, Jaime González
Physical Therapy Faculty Publications
Cultural competence is a "Foundational Behavior of Clinical Practice (CAATE, 2016)" for Athletic Training education. The objective of this study was to determine whether classroom activities are effective for improving cultural competence in undergraduate athletic training students. Twenty-seven participants completed an Inventory for Assessing the Process of Cultural Competence Among Healthcare Professionals-Student Version pre-test to establish a baseline level of cultural competence and completed a post-test after participating in the classroom activities. The mean score increased from 60.44 to 67.78 after participation in classroom activities exceeding the minimal detectable change of the tool and demonstrating significant improvement in cultural competence.
Intraosseous Hemangioma Of The Frontal Bone. Report Of A Case And Review Of The Literature, Joshua S. Brandner, Yeshwant B. Rawal, Louis J. Kim, Jasjit K. Dillon
Intraosseous Hemangioma Of The Frontal Bone. Report Of A Case And Review Of The Literature, Joshua S. Brandner, Yeshwant B. Rawal, Louis J. Kim, Jasjit K. Dillon
School of Dentistry Faculty Research and Publications
Intraosseous hemangiomas of the maxillofacial region are rare lesions that constitute less than 1% of all osseous tumors. A review of the literature on intraosseous hemangiomas of the skull and facial bones showed a limited number of publications, much of which were largely limited to case reports. This case report summarizes the workup and surgical treatment of a 39-year-old woman with an intraosseous hemangioma of the left frontal bone. The histology, treatment, and literature are reviewed.
Families Communicating About Health: Conceptualization And Validation Of The Family Health Communication Quotient Scale, Erin E. Gafner
Families Communicating About Health: Conceptualization And Validation Of The Family Health Communication Quotient Scale, Erin E. Gafner
Communication & Theatre Arts Theses
Research on family health communication is based in part on the assumption that families actually communicate about a wide variety of topics pertaining to their health and wellness (or lack thereof). However, whether they do communicate about health and wellness, and exactly what they communicate about concerning health and wellness as well as how often, remains undocumented. To begin to address this problem of documenting the extent to which families talk about health and wellness, this study adapted Warren and Neer’s (1986) Family Sex Communication Quotient to create and report the preliminary validation of a new measurement instrument called the …
Behavioral Determinants Of Exercise-Related Injury Prevention Program Participation, Emily M. Hartley
Behavioral Determinants Of Exercise-Related Injury Prevention Program Participation, Emily M. Hartley
Health Services Research Dissertations
Lower extremity injuries are common among the physically active population. There are many negative consequences associated with these injuries which have led to a shift in clinical practice towards prevention. Exercise-related injury prevention programs (ERIPPs) were created to prevent musculoskeletal injuries that occur due to participation in physical activity. However, one of the major limitations to their effectiveness is the compliance of the users to complete the prescribed exercises. It is imperative to better understand the reasons why compliance is low to develop implementation strategies and improve compliance rates.
The overarching purpose of this dissertation was to gain a better …
Oral Health Practices, Beliefs And Dental Service Utilization Of Albanian Immigrants In Milwaukee, Wisconsin: A Pilot Study, K. Rota, C. Spanbauer, Aniko Szabo, Christopher Okunseri
Oral Health Practices, Beliefs And Dental Service Utilization Of Albanian Immigrants In Milwaukee, Wisconsin: A Pilot Study, K. Rota, C. Spanbauer, Aniko Szabo, Christopher Okunseri
School of Dentistry Faculty Research and Publications
There is limited information on the oral health of Albanian immigrant population residing in the U.S. This creates a hinderance to developing and implementing appropriate dental care programs for the population. This study investigated oral health practices, beliefs, dental visits and associated factors of Albanian adults living in Milwaukee, Wisconsin. Purposive and snowball sampling methods were employed. Self-administered questionnaires were used to collect data on oral health practices, beliefs, dental visits and socio-demographic information. Descriptive and multivariable logistics regression were conducted. Overall, 266 adults were recruited, 54% male, 56% have lived 10 or more years in the U.S., 95% rated …
Role Of Dentists In Prescribing Opioid Analgesics And Antibiotics: An Overview, Ralph Dana, Amir Azarpazhooh, Nima Laghapour, Katie J. Suda, Christopher Okunseri
Role Of Dentists In Prescribing Opioid Analgesics And Antibiotics: An Overview, Ralph Dana, Amir Azarpazhooh, Nima Laghapour, Katie J. Suda, Christopher Okunseri
School of Dentistry Faculty Research and Publications
No abstract provided.
Nanomagnetic-Mediated Drug Delivery For The Treatment Of Dental Disease, Yadong Ji, Seung K. Choi, Ahmed S. Sultan, Kong Chuncai, Xiaoying Lin, Erfan Dashtimoghadam, Mary Anne Melo, Michael Weir, Huakun Xu, Lobat Tayebi, Ahihong Nie, Didier A. Depireux, Radi Masri
Nanomagnetic-Mediated Drug Delivery For The Treatment Of Dental Disease, Yadong Ji, Seung K. Choi, Ahmed S. Sultan, Kong Chuncai, Xiaoying Lin, Erfan Dashtimoghadam, Mary Anne Melo, Michael Weir, Huakun Xu, Lobat Tayebi, Ahihong Nie, Didier A. Depireux, Radi Masri
School of Dentistry Faculty Research and Publications
Maintaining the vitality of the dental pulp, the highly innervated and highly vascular, innermost layer of the tooth, is a critical goal of any dental procedure. Upon injury, targeting the pulp with specific therapies is challenging because it is encased in hard tissues. This project describes a method that can effectively deliver therapeutic agents to the pulp. This method relies on the use of nanoparticles that can be actively steered using magnetic forces to the pulp, traveling through naturally occurring channels in the dentin (the middle layer of the tooth). This method can reduce the inflammation of injured pulp and …
The Effect Of Partially Exposed Connective Tissue Graft On Root‐Coverage Outcomes: A Systematic Review And Meta‐Analysis, Austin Dodge, Jeffrey Garcia, Paul Luepke, Yu-Lin Lai, Moawia M. Kassab, Guo-Hao Lin
The Effect Of Partially Exposed Connective Tissue Graft On Root‐Coverage Outcomes: A Systematic Review And Meta‐Analysis, Austin Dodge, Jeffrey Garcia, Paul Luepke, Yu-Lin Lai, Moawia M. Kassab, Guo-Hao Lin
School of Dentistry Faculty Research and Publications
The aim of this systematic review was to compare the root‐coverage outcomes of using a partially exposed connective tissue graft (CTG) technique with a fully covered CTG technique for root coverage. An electronic search up to February 28th, 2017, was performed to identify human clinical studies with data comparing outcomes of root coverage using CTG, with and without a partially exposed graft. Five clinical studies were selected for inclusion in this review. For each study, the gain of keratinized gingiva, reduction of recession depth, number of surgical sites achieving complete root coverage, percentage of root coverage, gain of …
Trends In Self‐Reported Oral Health Of Us Adults: National Health And Nutrition Examination Survey 1999‐2014, Kar Yan Li, Christopher Okunseri, Colman Mcgrath, May C.M. Wong
Trends In Self‐Reported Oral Health Of Us Adults: National Health And Nutrition Examination Survey 1999‐2014, Kar Yan Li, Christopher Okunseri, Colman Mcgrath, May C.M. Wong
School of Dentistry Faculty Research and Publications
Objective
Single‐item self‐reported oral health (SROH) is a convenient and reliable measure for the assessment of population‐based oral health. However, little is known about trends and its associations among US adults. This study investigated trends in SROH (aged 20+ years) and the associated factors among adults living in the United States.
Methods
Self‐reported oral health data for 41 621 adults aged 20+ years from the National Health and Nutrition Examination Survey (NHANES) 1999 to 2014 were analysed. Survey‐weighted descriptive statistics were computed to provide nationally representative estimates. Multivariable logistic regression was performed separately for each survey period with SROH as …
Neuromuscular Adaptations Following Training And Protein Supplementation In A Group Of Trained Weightlifters, Christopher B. Taber, Kevin M. Carroll, Brad H. Deweese, Kimitake Sato, Charles A. Stuart, Mary Howell, Kenton Hall, Caleb Bazyler, Michael H. Stone
Neuromuscular Adaptations Following Training And Protein Supplementation In A Group Of Trained Weightlifters, Christopher B. Taber, Kevin M. Carroll, Brad H. Deweese, Kimitake Sato, Charles A. Stuart, Mary Howell, Kenton Hall, Caleb Bazyler, Michael H. Stone
Exercise Science Faculty Publications
The purpose of this study was to examine the effects of a recovery supplement compared with a placebo on muscle morphology in trained weightlifters. Vastus lateralis and muscle fiber cross sectional area of type I and type II fibers were compared between groups using a series of 2 × 2 (group × time) repeated measure ANOVAs. Both groups on average improved cross-sectional area of the vastus lateralis, type I and type II muscle fibers from pre-to-post but individual response varied within both groups. Greater magnitude of changes in type I and type II muscle fibers were observed for the placebo …
Foundations Of Health Information Technology (Undergraduate) Course Materials, Chi Zhang
Foundations Of Health Information Technology (Undergraduate) Course Materials, Chi Zhang
Computer Science and Information Technology Ancillary Materials
This is a collection of all materials used in Health Information Technology by Dr. Chi Zhang at Kennesaw State University, including lecture slides, assignments, and assessments, including a question bank.
Topics covered include:
- Clinical Financial Records
- Evidence-Based Medicine
- e-Prescribing
- Patient Bedside Systems
- Telemedicine
- Health Information Networks
- Cryptography
- Accreditation
- HIPAA Privacy and Security
Factors Affecting Reintubations After Cardiac And Thoracic Surgeries In Cardiac Intensive Care Unit Of A Tertiary Care Hospital, Khalid Maudood Siddiqui, Khalid Samad, Faisal Jonejo, Muhammad Faisal Khan, Khalid Ahsan Khalid Ahsan
Factors Affecting Reintubations After Cardiac And Thoracic Surgeries In Cardiac Intensive Care Unit Of A Tertiary Care Hospital, Khalid Maudood Siddiqui, Khalid Samad, Faisal Jonejo, Muhammad Faisal Khan, Khalid Ahsan Khalid Ahsan
Department of Anaesthesia
Background: Reintubation and readmission after cardiothoracic surgeries are not uncommon, and its reasons are multifactorial. The study goal was to identify the factors that contribute reintubation after cardiac and thoracic surgery in tertiary care hospital and to compare the outcome with international benchmark.
Methodology: A prospective, observational study was planned in Cardiac Intensive Care Unit (CICU). The study included all those patients who required readmission in CICU due to endotracheal intubation following cardiac and thoracic surgeries. The study was conducted from January to December 2016. The primary focus was to identify the reasons for reintubation within 72 h of extubation …
Measuring The Reliability Of The Early Expository Comprehension Assessment, Revised 3rd Edition, Garrett Frane Wilkes
Measuring The Reliability Of The Early Expository Comprehension Assessment, Revised 3rd Edition, Garrett Frane Wilkes
Theses and Dissertations
During the past several years, the Common Core State Standards has created a greater demand for students in public schools to comprehend and analyze expository text. In order to prepare students for work with expository text, beginning with kindergarten, more emphasis and standards have become prevalent in preschool classrooms as well. The Early Expository Comprehension Assessment, Revised 3rd Edition (EECA R-3) was developed to aid preschool teachers in determining what aspects of expository text a student understands, including recognition of different structure types. This study with the EECA R-3 extends previous studies using earlier iterations of the assessment. One hundred …
The Association Between Articulator Movement And Formant Histories In Diphthongs Across Speaking Contexts, Janae Valyn Christensen
The Association Between Articulator Movement And Formant Histories In Diphthongs Across Speaking Contexts, Janae Valyn Christensen
Theses and Dissertations
This study examined the effect of context on the association between formant trajectories and tongue and lip kinematics in the American English diphthongs /aɪ/ and /aʊ/. Seventeen native speakers of American English had electromagnetic sensors placed on their tongue and lips to record kinematic signals that were time-aligned with the corresponding acoustic recording. Speakers produced the diphthongs in isolation, in a single word rVl context, in a phrase hVd context, and in a sentence context. Kinematic data and the F1 and F2 trajectories were extracted from the middle 50% of each diphthong production. To allow direct comparison of signals with …
Preoperative Activity Level And Outcomes In Older Adult Cardiac Surgery Patients: A Pilot Study, Don Howard Sorensen
Preoperative Activity Level And Outcomes In Older Adult Cardiac Surgery Patients: A Pilot Study, Don Howard Sorensen
Theses and Dissertations
ABSTRACTPreoperative Activity Level and Outcomes in Older ¨Adult Cardiac Surgery Patients: A Pilot StudyDon Howard Sorensen Jr.College of Nursing, BYUMaster of SciencePurpose: To assess the relationship between preoperative physical activity levels and health related quality of life on intra- and post-hospital outcomes following scheduled cardiothoracic surgery in older adults.Rationale/Background: Adults age 50 and older tend to accumulate more sedentary time and are less physically active. Sedentary behavior is linked with early morbidity and death and may predispose patients to postoperative complications. Preoperative activity levels and its relationship to surgical outcomes is an underexplored area. Insight on this topic could influence …
Evaluating The Trustworthiness Of Consumer-Oriented Health Websites On Diabetes, Shahabedin Rahmatizadeh, Saeideh Valizadeh-Haghi
Evaluating The Trustworthiness Of Consumer-Oriented Health Websites On Diabetes, Shahabedin Rahmatizadeh, Saeideh Valizadeh-Haghi
Library Philosophy and Practice (e-journal)
Objective: The patients involvement in disease management can decrease economic burden on diabetic patients and society. Quality health information may help patients to involve in their health management. Thus, individuals need to find the additional information from other information resources such as health websites. Nevertheless, health websites vary in quality and reliability. Therefore, it is of great importance to identify trustable health websites on diabetes. Thus, the aim of the present study was to evaluate the reliability of health websites concerning diabetes.
Materials and methods: The keyword ‘’diabetes mellitus ‘’ was entered as a search term into the three …
Prenatal Exposure To Methadone Or Buprenorphine: Early Childhood Developmental Outcomes., Karol Kaltenbach, Kevin E O'Grady, Sarah H. Heil, Amy L. Salisbury, Mara G. Coyle, Gabriele Fischer, Peter R. Martin, Susan Stine, Hendrée E. Jones
Prenatal Exposure To Methadone Or Buprenorphine: Early Childhood Developmental Outcomes., Karol Kaltenbach, Kevin E O'Grady, Sarah H. Heil, Amy L. Salisbury, Mara G. Coyle, Gabriele Fischer, Peter R. Martin, Susan Stine, Hendrée E. Jones
Department of Pediatrics Faculty Papers
BACKGROUND: Methadone and buprenorphine are recommended to treat opioid use disorders during pregnancy. However, the literature on the relationship between longer-term effects of prenatal exposure to these medications and childhood development is both spare and inconsistent.
METHODS: Participants were 96 children and their mothers who participated in MOTHER, a randomized controlled trial of opioid-agonist pharmacotherapy during pregnancy. The present study examined child growth parameters, cognition, language abilities, sensory processing, and temperament from 0 to 36 months of the child's life. Maternal perceptions of parenting stress, home environment, and addiction severity were also examined.
RESULTS: Tests of mean differences between children …