Medicine and Health Sciences Commons^™

Long-Term Visual Outcomes In Optic Nerve Sheath Meningiomas Following Fractionated Stereotactic Radiotherapy, Sana Dastgheyb, Christian Fernandez, Md, Maria Werner-Wasik, Md, Voichita Bar-Ad, Md, David Andrews Md, James Evans, Md, Kevin Judy, Md, Sara Lally, Md, Carol Shields, Md, Arman Mashayekhi, Md, Wenyin Shi, Md, Phd, Christopher Farrell, Md

Sigma Xi Student Research Day

Introduction

Radiation therapy is often used for tumors of the optic nerve. The challenge with irradiating tumors surrounding structures associated with the eye is the risk of exposing the optic nerve, or other structures important to maintaining vision to potentially damaging radiation.

Fractionated stereotactic radiotherapy (FSRT) is commonly used for the treatment of optic nerve sheath meningiomas (ONSMs) for vision preservation. However, long term visual data in the literature is limited. We investigated visual outcomes in 27 patients with ONSMs after FSRT.

Visualization Of Fibronectin Assembly Using Crispr And Fluorescence Imaging, Brenda French, Sophie Astrof

Sigma Xi Student Research Day

Objectives

Surprisingly, the mechanisms of fibronectin assembly remain largely unknown. This project aims to elucidate the process by which fibronectin assembles through fluorescent labeling. Fluorescent tags allow for the visualization of fibronectin to clarify how this extracellular matrix protein may influence migration and signaling.

Evaluating The Effectiveness Of Text Messaging And Phone Call Reminders To Minimize No Show At Pediatric Outpatient Clinics In Pakistan: Protocol For A Mixed-Methods Study, Sana Saeed, Noureen Somani, Fatima Sharif, Abdul Momin Kazi

Department of Paediatrics and Child Health

Background: Missing health care appointments without canceling in advance results in a no show, a vacant appointment slot that cannot be offered to others. No show can be reduced by reminding patients about their appointment in advance. In this regard, mobile health (mHealth) strategy is to use text messaging (short message service, SMS), which is available on all cellular phones, including cheap low-end handsets. Nonattendance for appointments in health care results in wasted resources and disturbs the planned work schedules.
Objectives: The purpose of this study is to evaluate the efficacy of the current text messaging (SMS) and call-based …

Patterns Of Physical Activity In Sedentary Older Individuals With Type 2 Diabetes, Pearl G. Lee, Jinkyung Ha, Caroline S. Blaum, Kimberlee A. Gretebeck, Neil B. Alexander

College of Nursing Faculty Research and Publications

Background

The Community Healthy Activities Model Program for Seniors (CHAMPS) survey, summarized into weekly caloric expenditures, is a common physical activity (PA) assessment tool among older adults. Specific types of PA reported in the CHAMPS have not been systematically analyzed. We applied latent class analysis to identify the patterns of PA among sedentary older adults with diabetes reported in the CHAMPS survey.

Methods

Latent class models of PA were identified using the CHAMPS survey data reported by 115 individuals aged ≥60 years with type 2 diabetes whom volunteered for a clinical study of PA. Multinomial logistic regression was used to …

A Behavioral Lifestyle Intervention Enhanced With Multiple-Behavior Self-Monitoring Using Mobile And Connected Tools For Underserved Individuals With Type 2 Diabetes And Comorbid Overweight Or Obesity: Pilot Comparative Effectiveness Trial, Jing Wang, Chunyan Cai, Nikhil Padhye, Philip Orlander, Mohammad Zare

Faculty, Staff and Student Publications

BACKGROUND: Self-monitoring is a cornerstone of behavioral lifestyle interventions for obesity and type 2 diabetes mellitus. Mobile technology has the potential to improve adherence to self-monitoring and patient outcomes. However, no study has tested the use of a smartphone to facilitate self-monitoring in overweight or obese adults with type 2 diabetes mellitus living in the underserved community.

OBJECTIVE: The aim of this study was to examine the feasibility of and compare preliminary efficacy of a behavioral lifestyle intervention using smartphone- or paper-based self-monitoring of multiple behaviors on weight loss and glycemic control in a sample of overweight or obese adults …

A Mini Review Of The Zoonotic Threat Potential Of Influenza Viruses, Coronaviruses, Adenoviruses, And Enteroviruses, E. S. Bailey, J. K. Fieldhouse, J. Y. Choi, G. C. Gray

Public Health

No abstract provided.

The Validity Of Online Patient Ratings Of Physicians, Jennifer L. Priestley, Yiyun Zhou, Robert Mcgrath

Faculty Articles

Background: Information from ratings sites are increasingly informing patient decisions related to health care and the selection of physicians.

Objective: The current study sought to determine the validity of online patient ratings of physicians through comparison with physician peer review.

Methods: We extracted 223,715 reviews of 41,104 physicians from 10 of the largest cities in the United States, including 1142 physicians listed as “America’s Top Doctors” through physician peer review. Differences in mean online patient ratings were tested for physicians who were listed and those who were not.

Results: Overall, no differences were found between the online patient ratings based …

What's Happening: April 9, 2018, Maine Medical Center

What's Happening

No abstract provided.

Non-Medical Use Of Prescription Drugs And Sexual Risk Behaviors Among Depressed Adolescents, Michael S. Dunn, John F. Yannessa

Journal of Adolescent and Family Health

Non-medical prescription drug abuse is an issue that has plagued adolescents in the United States over the past decade and more. Also, depression is prevalent among our youth with 31% reporting multiple depressive episodes in the past year. As such, the purpose of this study was to assess the relationship between non-medical use of prescription drugs (NMUPD) and sexual behaviors among depressed high school students. Data was derived from the 2015 Youth Risk Behavior Survey (n=15,624). This national study is conducted every odd year, and is a representative sample of high school students in the United States. Logistic regression was …

Cardiomems In Heart Failure Management: Failure Is Not The Only Option, Rachel Kathryn Plambeck

Nursing Capstones

No abstract provided.

Success And Limitations Of Hepatitis C Screening In The Inpatient Setting, Madalene Zale, Mphc, Priya Mammen, Md, Mph

College of Population Health Posters

This study evaluates the outcomes that a state level mandate for HCV screening with HCV-Antibody-only has on linkage to care and access to treatment, compared to a specific programmatic effort, which includes HCV confirmation.

An Education Intervention To Increase Rounding And Toileting And Reduce Falls In A Hospital Acute Care Of The Elderly (Ace) Unit, Amelia Grayson

Doctoral Projects

Introduction: Falls are the most common accident reported in acute care hospitals and patients who are 65 and older are the most vulnerable. Falls can lead to physical and emotional injury, reduced mobility and functioning, increased length of hospital stay, increased healthcare costs, and admission to long-term care facilities. In 2008, the Center for Medicare & Medicaid Services (CMS) has eliminated reimbursement to hospitals for treatment of injuries resulting from a fall during hospitalization. Research on fall prevention in adult acute care found multifactorial interventions that address multiple risk factors for falls are the most successful at prevention. This …

Impact Of Podcasting On Learning Outcomes In Associate Degree Nursing Students, Daira D. Wilson

Nursing Theses and Dissertations

The dawn of the Information Age has provided rapid advances in technology that have improved lives and produced better tools for caring for each other. Nursing has begun to employ many of these new technologies and nurses are at the forefront of deciding how these innovations might best help patients. New technologies have made their way into schools of nursing and students are benefitting from improved learning experiences. Nursing faculty are leading the way in providing new learning opportunities to students through a multitude of technological advances. One of these advances is podcasting. Podcasting provides students the ability to listen, …

Markers Of Cardiometabolic Risk And Thyroid Dysfunction In U.S. Adolescents: Nhanes Iii, Jonathan Austin

Theses and Dissertations

The global prevalence of metabolic syndrome (MetS) and its associated components (high fasting glucose, waist circumference, blood pressure, triglycerides, and low HDL) have increased over the past few decades. In addition, abnormal thyroid hormone levels have been found to manifest in a cascade of metabolic dysfunction, which may be linked to MetS in youth. PURPOSE: The purpose of the study is to investigate the association between MetS, its components, and markers of thyroid function in a nationally-representative sample of adolescents. METHODS: The National Health and Nutrition Examination Survey III (1988-1994) collected data on the components of metabolic syndrome and thyroid …

Minnesota Dentists’ Opinion Of The Dental Therapy Workforce Model, Marguerite J. Rogers 4435350

Dental Hygiene ETDs

The state of Minnesota developed the dental therapy workforce model to help alleviate the disparity in access to dental care. Despite success in other countries and acceptance by other professional organizations in the United States, some dentists continue to oppose this workforce model. The purpose of this study was to quantify Minnesota dentists’ attitudes regarding the utilization of dental therapists in that state. A survey was constructed that queried dentists’ opinion on dental therapists performing irreversible procedures and dental therapists alleviating the disparity in access to dental care. A stratified random sample of 1,000 dentists were invited to participate in …

Transition Of Care For Young Adults With Cleft Lip And Palate: We’Ve Got Some Growing Up To Do, Brenda Louw, Linda Vallino

ETSU Faculty Works

Participants will be able to:

• Describe the characteristics and needs of young adults with CLP.
• Discuss the model of transition of care for the young adult with CLP.
• Extrapolate strategies that teams could use to improve the care of young adults with CLP.

Full abstract available through The Cleft Palate-Craniofacial Journal.

Effects Of Load Carriage And Surface Inclination On Linear And Non-Linear Postural Variability, Rahul Soangra, Hema Bhatt, Ehsan Rashedi

Physical Therapy Faculty Articles and Research

Understanding of inclined-work-related risk of falls and developing novel practical engineering controls for reducing this risk of falls among hilly working population remains in high demand. Standing on sloped surfaces provides a unique environment for examining the biomechanics and neural control of standing. The present investigation examined the variability of postural signals when standing on inclined surfaces and with load carriages by linear and nonlinear analysis. The purpose of this study was to determine if the sloped surface deteriorated in postural stability among healthy individuals with two distinctive kinds of load carriage methods head versus posterior load carriage. We also …

Twist Promotes Tumor Metastasis In Basal-Like Breast Cancer By Transcriptionally Upregulating Ror1, Jingying Cao, Xin Wang, Tao Dai, Yuanzhong Wu, Meifang Zhang, Renxian Cao, Ruhua Zhang, Gang Wang, Rou Jiang, Binhua P. Zhou, Jian Shi, Tiebang Kang

Markey Cancer Center Faculty Publications

Rationale: Twist is a key transcription factor for induction of epithelial-mesenchymal transition (EMT), which promotes cell migration, invasion, and cancer metastasis, confers cancer cells with stem cell-like characteristics, and provides therapeutic resistance. However, the functional roles and targeted genes of Twist in EMT and cancer progression remain elusive.

Methods: The potential targeted genes of Twist were identified from the global transcriptomes of T47D/Twist cells by microarray analysis. EMT phenotype was detected by western blotting and immunofluorescence of marker proteins. The dual-luciferase reporter and chromatin immunoprecipitation assays were employed to observe the direct transcriptional induction of ROR1 by Twist. A lung …

Network Specialization During Adolescence: Hippocampal Effective Connectivity In Boys And Girls, Jeffrey D. Riley, E. Elinor Chen, Jessica Winsell, Elyssia Poggi Davis, Laura M. Glynn, Tallie Z. Baram, Curt A. Sandman, Steven L. Small, Ana Solodkin

Psychology Faculty Articles and Research

Adolescence is a complex period of concurrent mental and physical development that facilitates adult functioning at multiple levels. Despite the growing number of neuroimaging studies of cognitive development in adolescence focusing on regional activation patterns, there remains a paucity of information about the functional interactions across these participating regions that are critical for cognitive functioning, including memory. The current study used structural equation modeling (SEM) to determine how interactions among brain regions critical for memory change over the course of adolescence. We obtained functional MRI in 77 individuals aged 8–16 years old, divided into younger (ages 8–10) and older (ages …

Antibody-Drug Conjugates For Cancer Therapy: Chemistry To Clinical Implications, Nirnoy Dan, Saini Setua, Vivek K. Kashyap, Sheema Khan, Meena Jaggi, Murali M. Yallapu, Subhash C. Chauhan

School of Medicine Publications

Chemotherapy is one of themajor therapeutic options for cancer treatment. Chemotherapy is often associated with a low therapeutic window due to its poor specificity towards tumor cells/tissues. Antibody-drug conjugate (ADC) technology may provide a potentially new therapeutic solution for cancer treatment. ADC technology uses an antibody-mediated delivery of cytotoxic drugs to the tumors in a targeted manner, while sparing normal cells. Such a targeted approach can improve the tumor-to-normal tissue selectivity and specificity in chemotherapy. Considering its importance in cancer treatment, we aim to review recent efforts for the design and development of ADCs. ADCs are mainly composed of an …

Week Of April 9, 2018, New York Medical College

InTouch

• The New Faculty Lounge is Now Open
• Medical Students Volunteer As Westchester Science and Engineering Fair Judges
• Chancellor Halperin Hosts Museum Visit
• The Latest Issue of Chironian is Now Online

Alternative Techniques For Alfaxalone Anesthesia Induction In Dogs And Cats, Angie Lagos

LSU Master's Theses

Alfaxalone is a neuroactive synthetic steroid (Brewster & Bodor, 1990) that produces anesthetic induction with dose- and speed-dependent cardiorespiratory depression in dogs and cats (Chiu et al. 2016; Warne et al., 2015). At clinical doses in unpremedicated dogs (2 mg kg^-1) and cats (5 mg kg^-1), alfaxalone induces a mild decrease in systemic vascular resistance, systemic blood pressure (Muir et al., 2009; Muir et al., 2008), apnea, hypoventilation, and hypoxemia (Muir et al. 2009; Muir et al., 2008). The cardiorespiratory side effects from alfaxalone induction could be prevented by reducing the total dose of alfaxalone necessary …

Counseling The Media: Bridging Pop Cultural Borders With The Mental Health Profession, Stephanie J. Durham, Michael A. Desposito

Ray Browne Conference on Cultural and Critical Studies (2015-2021)

Professional counseling is often defined as a professional relationship meant to empower diverse people towards their mental health and wellness goals (Kaplan, Tarvydas, & Gladding, 2014). While counselors continue to provide professional services in many settings, counseling is not always portrayed in a positive light within television and film. Shows such as 13 Reasons Why and How I Met Your Mother both portray an inaccurate perception of counseling characters who disregard their ethical duties despite the American Counseling Association’s Code of Ethics (2014) mandates for safe-guarding the wellbeing of those seeking counseling, honoring multicultural diversity, and advocating for social justice. …

Medical School Watercooler Newsletter - April 8, 2018, Lindsey Lyle

Watercooler Newsletter

This is the April 8, 2018 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents Include:

• Register Now: Joy in Practice Burnout Education Session
• USA SNMA Health Fair a Success
• USA Medical Student Presents Research at 2018 SAHM Meeting in Seattle
• USA Student Health Center Featured in Journal of American College Health
• USA College of Medicine Welcomes New Emergency Medicine Faculty

Shared Decision-Making As Experienced By Rehabilitation Students On An International Service-Learning Trip: A Phenomenological Investigation, Mary Zadnik, Suzanne Trotter, Thomas Werner

Occupational Therapy Collection

The value of service-learning has been well documented in medical and allied health education (Abedini, Gruppen, Kolars, & Kumagai, 2012; Ekelman, Dal Bello-Haas, Bazyk, & Bazyk, 2003; Pechak, Gonzalez, Summers, & Capshaw, 2013; Pechak & Thompson, 2009; Ryan-Krause, 2016). Several studies have been conducted looking at cultural experiences and clinical reasoning (Corbett & Fickert, 2009; Sheppard & Landry, 2015; Nouvet, Chan & Schwartz, 2016). What has not been well-examined though is the concept of shared decision-making by those engaged in service-learning. The purpose of this phenomenological investigation (i.e. study) was to identify how occupational therapy (OT) and physical therapy (PT) …

Personality Types Among Athletic Trainers, Anthony Bartko

Masters Theses/Capstone Projects

This research study analyzed the personality types among the Athletic Training (AT) profession. With no research present in the field of Athletic Training, research from similar fields like Physical Therapy, and Occupational Therapy were referenced throughout the research process. Throughout the literature review process it was observed that previous researchers used the Meyers-Briggs Type Indicator (MBTI) assessment tool to identify personality types. A MBTI assessment tool was used to identify personality types among the participants, and a demographics survey comprised of nine questions was used to determine participant’s experience in the Athletic Training profession. After reviewing previous studies from other …

Dealing With Deans And Academic Medical Center Leadership: Advice From Leaders., Fred Sanfilippo, Deborah Powell, Robert Folberg, Mark Tykocinski

Department of Medicine Faculty Papers

The 2017 Association of Pathology Chairs Annual Meeting included a session for department chairs and other department leaders on "how to deal with deans and academic medical center leadership." The session was focused on discussing ways to foster positive relationships with university, medical school, and health system leaders, and productively address issues and opportunities with them. Presentations and a panel discussion were provided by 4 former pathology chairs who subsequently have served as medical deans and in other leadership positions including university provost, medical center CEO, and health system board chair. There was a strong consensus among the participants on …

Efficacy Of A Three-Week Intervention Program For A School-Aged Children In The Areas Of Language, Literacy, Phonological Awareness, And Auditory Processing, Nicole Weis

Honors Theses

Research demonstrates that competency in the areas of language, phonological awareness, and auditory processing is vital to academic success in children, as well as in navigating adult life. The study's purpose is to measure the efficacy of an intensive, three-week summer camp therapy program for school-aged children in addressing these areas, and to identify areas of strength and weakness in the program and interventions implemented. Programs utilized during the summer camp included Visualizing and Verbalizing(TM), Lindamood Phoneme Sequencing(R), On Cloud Nine(R), Color My Conversation, Differential Processing Training Program(TM), as well as science experiments, and snack and crafts time.

Azbio Sentence Accuracy For English As A Second Language Adults In Quiet And Background Noise, Alexandra Wiist

Honors Theses

The objective of this study is to examine indications of a significant difference in listening ability between native English speakers and English as a Second Language (ESL) students in quiet and background noise specifically on the AZBIO Sentence test. Three Language groups were analyzed: Korean, Portuguese, and Spanish. AZBIO lists were used to assess ESL students' ability to repeat sentences. An analysis of errors was completed to determine variance and similarities between the four language groups. Native English speakers had no difficulty repeating sentences in either condition, ESL students' data suggested more difficulty in both quiet and background noise and …

Unicentric Epithelioid Hemangioendothelioma Of The Calcaneus: A Case Report And Review Of Literature, Mark C. Plumby, Patrick Bacaj, Brock A. Lindsey

Clinical and Translational Science Institute

Background: This review of the literature combined with a clinical case will allow the illustration of a favorable outcome of this variable low grade malignancy, display a role for limb salvage surgery with intralesional treatment, and ofer a clinical example of epithelioid hemangioendothelioma, a rare malignancy. Case presentation: The case report presents a case of solitary epithelioid hemangioendothelioma (EHE) of the calcaneus in a 60-year-old male. Primary vascular tumors of the bone are rare; however, EHE is one of the most common primary malignant vascular tumors to occur in bone. A review of the literature found few cases that involved …