Medicine and Health Sciences Commons^™

An Opportunity For Pharmacists To Help Improve Coordination And Continuity Of Patient Health Care, Jon C. Schommer, Lawrence M. Brown, Ryan (Alyssa) Bortz, Alina Cernasev, Basma T. Gomaa, Keri D. Hager, Lisa Hillman, Olihe Okoro, Serguei V. S. Pakhomov, Paul L. Ranelli

Pharmacy Faculty Articles and Research

Pharmacist workforce researchers are predicting a potential surplus of pharmacists in the United States that might result in pharmacists being available for engagement in new roles. The objective for this study was to describe consumer opinions regarding medication use, the health care system, and pharmacists to help identify new roles for pharmacists from the consumer perspective. Data were obtained from the 2015 and 2016 National Consumer Surveys on the Medication Experience and Pharmacist Roles. Out of the representative sample of 36,673 respondents living in the United States, 80% (29,426) submitted written comments at the end of the survey. Of these, …

Evaluation Of Endothelial Cell Responses To Elevated Glucose, Gabriella Sugerman

Master's Theses

Developing a tissue-engineered Blood Vessel Mimic (BVM) to represent diabetic macrovascular disease could expedite design of new vascular devices specifically tailored to diabetic patients. In contribution toward this model, this thesis assessed Human Umbilical Vein Endothelial Cell (HUVEC) responses to high glucose conditions. Interleukin 6 (IL-6) and Cluster of Differentiation 36 (CD36) were selected to signify oxidative stress activity, a hallmark of diabetic macrovascular disease. Next, activity of potential reference genes B2M, HPRT1, and ACTB was assessed. All genes were found to exceed acceptable variability, so the E-ΔC T method of data analysis was selected. Next, cellular responses to high …

Exploring The Association Between Female Genital Mutilation/Cutting And Hiv, Evidence To End Fgm/C Programme Consortium

Reproductive Health

Female genital mutilation/cutting (FGM/C) threatens the health and well-being of girls in a variety of ways. Some experts have suggested that human immunodeficiency virus (HIV) may be among the practice’s adverse health outcomes. They theorize that because women with FGM/C risk genital trauma and bleeding during intercourse, their chances of acquiring HIV from an infected male partner are increased. While evidence that FGM/C increases susceptibility to HIV could bolster FGM/C eradication efforts, this connection has received limited research attention. This brief highlights the Evidence to End FGM/C program’s findings on the current state of evidence on the association between FGM/C …

Meta-Analysis Of The Incidence And Patterns Of Second Neoplasms After Photon Craniospinal Irradiation In Children With Medulloblastoma, Abhishek Bavle, Sayani Tewari, Amy Sisson, Murali Chintagumpala, Michael Anderson, Arnold C Paulino

Library Staff Publications

BACKGROUND: Second neoplasms (SNs) are a well-established long-term adverse effect of radiation therapy (RT), but there are limited data regarding their incidence and location relative to the radiation field, specific to medulloblastoma (MB) survivors after craniospinal irradiation (CSI).

METHODS: A systematic literature review, per Preferred Reporting Items for Systematic Reviews and Meta-Analyses, identified six studies reporting the incidence and locations of SNs for 1,114 patients with MB, after CSI, with a median follow-up of ∼9 years (7.6-15.4 years). The study-specific cumulative incidence (CI) of SNs, second benign neoplasms (SBNs), and second malignant neoplasms (SMNs) were standardized to a 10-year time …

A Quality Protocol For A Federally Qualified Health Center: A Pilot Project, John K. Dekock

Doctoral Projects

Federally Qualified Health Centers (FQHCs) have become a vital part of access to care for low socioeconomic status individuals. The federal government has allocated funds to be distributed to FQHCs via Medicare and Medicaid reimbursement based on insurance claims and through the Health Resources and Service Administration (HRSA) via grants and incentives based on Uniform Data System (UDS) reporting. Federally Qualified Health Centers must complete annual uniform data system (UDS) reporting on quality indicator metrics to receive grants and incentives from HRSA. The Health Resources and Service Administration (HRSA) funded health centers are expected to have ongoing quality assurance and …

Transcriptomic Signatures Of Schizophrenia Revealed By Dopamine Perturbation In An Ex Vivo Model, Jubao Duan, Harald Hh Goring, Alan R. Sanders, Winton Moy, Jessica Freda, Eugene I. Drigalenko, Mark Z. Kos, Deli He, Pablo V. Gejman

School of Medicine Publications

The dopaminergic hypothesis of schizophrenia (SZ) postulates that dopaminergic over activity causes psychosis, a central feature of SZ, based on the observation that blocking dopamine (DA) improves psychotic symptoms. DA is known to have both receptor- and non-receptor-mediated effects, including oxidative mechanisms that lead to apoptosis. The role of DA-mediated oxidative processes in SZ has been little studied. Here, we have used a cell perturbation approach and measured transcriptomic profiles by RNAseq to study the effect of DA exposure on transcription in B-cell transformed lymphoblastoid cell lines (LCLs) from 514 SZ cases and 690 controls. We found that DA had …

Effect Of Skin-To-Skin Contact On Parents' Sleep Quality, Mood, Parent-Infant Interaction And Cortisol Concentrations In Neonatal Care Units: Study Protocol Of A Randomised Controlled Trial, Charlotte Angelhoff, Ylva Thernström Blomqvist, Charlotte Sahlén Helmer, Emma Olsson, Shefaly Shorey, Anneli Frostell, Evalotte Mörelius

Research outputs 2014 to 2021

INTRODUCTION: Separation after preterm birth is a major stressor for infants and parents. Skin-to-skin contact (SSC) is a method of care suitable to use in the neonatal intensive care unit (NICU) to minimise separation between parents and infants. Less separation leads to increased possibilities for parent-infant interaction, provided that the parents' sleep quality is satisfactory. We aimed to evaluate the effect of continuous SSC on sleep quality and mood in parents of preterm infants borndischarge.

METHODS AND ANALYSIS: A randomised intervention study with two arms-intervention versus standard care. Data will be collected from 50 families. Eligible families will be randomly …

The Relationship Between Mental Health And Ultra-Running: A Case Study, Joshua Justin Cook

Graduate Theses and Dissertations

This instrumental case study sought to explore the relationship between ultra-running and mental health through the lived experiences of a single participant who self-identifies as an ultra-runner. Three research questions were used to explore this relationship; how did the individual decide to participate in ultra-running, what aspects of ultra-running impact the participant’s mental health, and how has engaging in ultra-running impacted the participant’s mental health? The case study utilized three semi-structured interviews, two participant observations, video documentary review, and journaling to answer these questions. A thematic analysis of the data revealed four essential themes; 1) Development of participation, 2) Promotes …

Bios 6135 - Topics Of Inference In Biostatistics, Lili Yu

College of Public Health: Faculty Syllabi (2014-2021)

This course provides an introduction to the fundamental knowledge of derivatives, integrals, and matrix algebra found in biostatistical inference. The course will introduce the theory of quadratic forms and their applications to distributions, the method of maximum likelihood estimation, likelihood ratio tests, restricted maximum likelihood, and the basis for inferences derived from hypothesis testing and confidence intervals. Emphasis will be placed on how these techniques are used in biostatistical problems and applications using examples from the pharmaceutical industry.

Bios 6331: Regression Analysis In Biostatistics, Jingjing Yin

College of Public Health: Faculty Syllabi (2014-2021)

This course introduces the methods for analyzing biomedical and health related data using linear regression models. The course will introduce the student to matrix algebra as used in linear models. The course will involve model selection, diagnosis and remedial techniques to correct for assumption violations. The students will learn how to apply SAS procedures PROC REG, PROC CORR, and PROC GLM, etc and interpret the results of analysis. Emphasis will also be placed on the development of critical thinking skills.

Bios 6531 – Categorical Data Analysis, Haresh Rochani

College of Public Health: Faculty Syllabi (2014-2021)

This course introduces statistical methods for analyzing both univariate and multivariate categorical data and count in medical research and other health-related fields. The course will introduce how to distinguish among the different measurement scales, the commonly used statistical probability distribution and inference methods for categorical and count data. Emphasis will be placed on the application of the methodology and computational aspects rather than theory. The students will learn how to apply SAS procedures to data and interpret the results.

Bios 7544 – Data Management For Biostatistics, Jingjing Yin

College of Public Health: Faculty Syllabi (2014-2021)

This course emphasizes data management and software applications using the SAS (Statistical Analysis System) software package. It will introduce the student to SAS codes for: inputting and outputting data, creating temporary and permanent data sets, creating formatted and labeled SAS data sets, merging and connecting SAS data sets, creating output using the TABULATE and REPORT procedures, debugging a SAS program that includes the TABULATE, REPORT and SQL procedures, using character functions in SAS, using a random number generator, probability distributions, arrays, and date and time functions. Students will also write a simple and complex query using the SQL procedure; create, …

Bios 9130—Research Seminar In Biostatistics, Hani M. Samawi

College of Public Health: Faculty Syllabi (2014-2021)

This course is designed to provide the student with the current best practices in biostatistical consulting. Topics include: Identifying and constructing appropriate questions to ask clients regarding their consultation request, an overview of appropriate statistical methods and SAS software procedures to use for specific study designs and statistical analysis of collected data, directing a consultation appointment without faculty lead, conducting exploratory data analyses, conducting effective analyses based on appropriate statistical methods, conducting needed simulation (including Monte Carlo methods and Bootstrap methods) and providing oral and written communication of statistical findings. 3 credit houses

Bios 9135– Advanced Survival Analysis, Lili Yu

College of Public Health: Faculty Syllabi (2014-2021)

This course will be placed on the theory on survival data. Counting processes and martingale method will be introduced. Emphasis will be place on the applications of the theory on the methodologies for survival data, such as Kaplan-Meier estimate, log-rank test, Cox model, etc. The students will learn how to use R language to setup survival dataset and perform analysis.

Bios 9231: Bayesian Statistics I, Xinyan Zhang

College of Public Health: Faculty Syllabi (2014-2021)

This course provides the student with an introduction Bayesian analysis and compares Bayesian methods to that of frequentists. The course includes selection of prior distributions, computing posterior distributions, and conjugate models such as the Beta-Binomial, Normal-Normal, and Gamma-Poisson models. Bayesian inference using point and interval estimation, Bayesian hierarchical models, and exchangeability will be explored. Topics including Empirical Bayes versus a fully Bayes approach, Markov Chain Monte Carlo methods and model checking using Bayes factors and sensitivity analyses will be included. Prerequisite: A minimum grade of "B" in BIOS 9131, or permission from instructor.

Epid 7233– Public Health Surveillance Methods, Jian Zhang

College of Public Health: Faculty Syllabi (2014-2021)

This course will provide students with a strong foundation in public health surveillance of both health conditions and risk factors. The course will teach the theory and practice of surveillance supported by many examples of surveillance systems from the developed and developing world. The class will build on and reinforce basic epidemiologic concepts. Students will be given the opportunity to design and evaluate a surveillance system.

Cohe 7232 A – Health Promotion Planning, Andrew Hansen

College of Public Health: Faculty Syllabi (2014-2021)

Introduces the student to the theory and application of planning and evaluation principles. Planning and evaluation skills will be developed that can be utilized in a variety of health-related settings. Familiarizes students with theories and models from the social and behavioral sciences and health education used in behavior change interventions. Emphasizes the planning and implementing of community health interventions at multiple ecological levels.

Bios 9331—Meta Analysis, Robert Vogel

College of Public Health: Faculty Syllabi (2014-2021)

This course is designed to address research questions in biomedical and other health-related research using meta-analysis techniques. A survey of past and present challenges of such techniques will be addressed, as will a mixture of Frequentist and Bayesian approaches to meta-analysis. Typical research questions found in health-related issues such as prevention, diagnosis, treatment, and policy will be constructed, followed by the methodologies to analyze such health-related questions. The course will focus on modeling and implementation issues in meta-analysis for biostatistical applications. In particular, this course will emphasize such topics as heterogeneous study results, combining studies with different designs, advantages and …

Bios/Pubh 6541: Biostatistics Fall 2018, Xinyan Zhang

College of Public Health: Faculty Syllabi (2014-2021)

This 4 credit course examines statistics in public health and related sciences, including sampling, probability, basic discrete and continuous distributions, descriptive statistics, hypothesis testing, confidence intervals, categorical data analysis, regression, and correlation. Emphasis will be on the development of critical thinking skills and health data analysis applications with computer software.

Chbe 9235 Communication And Advocacy, Moya L. Alfonso

College of Public Health: Faculty Syllabi (2014-2021)

This course is designed to familiarize students with the history and current applications of health communication theory and strategies to public health practice and research. This course examines how to structure, develop and evaluate social marketing, media advocacy, risk communication and advocacy skills for change. In addition, systematic qualitative data collection processes such as interviewing skills, participant observation and focus groups will be developed. Emphasis is placed on critical thinking skills to help students analyze and utilize these skills in research and practice.

Chbe 9130-A: Research Methods In Community And Behavioral Health, Joseph Telfair

College of Public Health: Faculty Syllabi (2014-2021)

General Course Description: This course introduces students to research methods in health science. Development and presentation of practicum and research proposals will be the focus of the course. Additional emphasis will be placed on writing skills that will contribute to research projects and grant applications.

Envh 8335 A – Global Water And Sanitation Spring, Asli Aslan

College of Public Health: Faculty Syllabi (2014-2021)

The global water crisis is the most serious threat to human health. Poor water quality, lack of sanitation and inadequate access to clean water resources are one of the major causes of global health disparities. Current issues such as changing climate, decaying infrastructure and reemerging waterborne diseases are also contributors for disease transmission within vulnerable populations. This course analyzes the key drivers that affect global water quality and human health. Real world case scenarios will be examined to develop sustainable and appropriate solutions that consider environmental, individual, cultural, and economic factors.

Envh 7234 – Environmental Toxicology, Evans Afriyie-Gyawu

College of Public Health: Faculty Syllabi (2014-2021)

This course introduces students to concepts associated with the lethal and sub-lethal effects of environmental and occupational stressors on humans and other living organisms.

Cohe 7234 – Community Health Analysis And Assessment, Moya L. Alfonso

College of Public Health: Faculty Syllabi (2014-2021)

This course familiarizes students with concepts and approaches for community health assessment and analysis. This includes discussion of social action, organizational development, policy advocacy, capacity building, community diagnosis (needs assessment), social networking and coalition formation to bring about health and quality of life improvement. Special focus will be placed on the application of qualitative, quantitative, and mixed methods and CBPR approaches for assessment.

Epid 7134 – Research Methods Ii, Logan Cowan

College of Public Health: Faculty Syllabi (2014-2021)

This course provides instruction and hands-on experience in the analysis and interpretation of data from epidemiologic studies. Topics to be covered include epidemiology research questions that can be addressed by cross-sectional, case-control and cohort studies; the rationale underlying the major techniques used to analyze data from these studies; the conditions under which these methods are appropriate and their relative advantages and disadvantages. Attention will be given to how interactions, confounders and nonlinear relationships among variables can be addressed along with interpretation of statistical software output from epidemiologic studies employing these designs and analytical methods.

Hspm 7232: Public Health Finance, Charles Owens

College of Public Health: Faculty Syllabi (2014-2021)

This course examines the structure and functioning of the finance components of the public health system. Public health organizations will be discussed within the context of the financial environment that includes financial management, managerial accounting, revenue cycle management, and funding and financial management of grants/contracts. The course also examines key financial tools and analyses for financially related decision making within the principles of strategic management applied to public health organizations amid a dynamic changing environment.

Hspm 7133 Section A: Public Health Policy & Ethics, Bill Mase

College of Public Health: Faculty Syllabi (2014-2021)

The course prepares learners to understand complex health and human service-related systems in order to inform effective practice-based ethical decision-making. The primary focus of the course relates to public health policy and practice. Major content areas include health policy institutions, the health policy process, ethical political considerations, social determinants of health, workforce, health care financing, medical technology, health care organizations, the public health system, primary care systems, and other health-related issues impacting the health of the public. Strategies of implementing change through policy making and the legislative process are covered.

Hspm 7335: Healthcare Operations Management, Linda Kimsey

College of Public Health: Faculty Syllabi (2014-2021)

This course examines operational issues in health care management. Topics include systems analysis, continuous quality improvement and re-engineering, demand forecasting, facility location and design models, decision analysis techniques, linear programming, queuing and waiting models, inventory control models, and statistical quality control. The goal is to instill an understanding of the language, applications, and limitations of quantitative models with regard to decision-making and problem solving in health care organizations.

Hspm 7336: Supply Chain Management, Linda Kimsey

College of Public Health: Faculty Syllabi (2014-2021)

The healthcare supply chain is a vital core business component of the health organization with the mission of delivering the technological elements of the patient care process to the providers of care. From strategic sourcing and purchasing, acquisition, logistics, inventory management, to point of use applications, this course provides understanding, knowledge and evaluation models to operate and manage an organization’s enterprise resource planning and management system, specifically with regard to the supply chain system and the management of that system as evaluated from a strategic, operations management and financial perspective.

Phld 9130 – Public Health Research Methods, Yelena N. Tarasenko

College of Public Health: Faculty Syllabi (2014-2021)

The course focuses on the concepts and methods of health services and public health research. It is structured around the primary stages of research proposal development. It is designed for DrPH students in the College of Public Health and other graduate or professional students who have successfully completed the appropriate prerequisites. By the completion of this course, Students will acquire the necessary knowledge and skills to write a research proposal, plan for the dissertation, and develop and carry-out research projects.