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2018

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Full-Text Articles in Medicine and Health Sciences

Comparing Interprofessional Socialization In Mixed Discipline And Nursing Student Only Cohorts, Kara Groom Oct 2018

Comparing Interprofessional Socialization In Mixed Discipline And Nursing Student Only Cohorts, Kara Groom

Dissertations (1934 -)

A main cause of patient safety incidents are avoidable failures in communication between health professionals. In response, healthcare has entered an era of interprofessionalism in education and patient care. A challenge to substantiating the value of interprofessional education (IPE) has been a limited number of studies that assess the effectiveness of IPE interventions compared to education interventions in which professions were learning separately from one another. This research project helps fill this gap and measures the differences in student interprofessional socialization (IS) between an IPE cohort and a usual care group of one-discipline learners. The purpose was to compare IS …


Nur 3110 The Nurse Leader Within, Syllabus, Linda Ann Paradiso Oct 2018

Nur 3110 The Nurse Leader Within, Syllabus, Linda Ann Paradiso

Open Educational Resources

Syllabus for NUR 3110 The Nurse Leader Within - a 15 week semester course for pre-licensure nursing students or nurses earning their baccalaureate degree. Every nurse is a leader, regardless of title or position within an organization. In this course you will learn to develop your voice and skills in order to lead teams of people who care for persons in need of any type of medical care.


Jefferson Digital Commons Quarterly Report: July-September 2018, Kelsey Duinkerken, Msi, James Copeland, Libt Oct 2018

Jefferson Digital Commons Quarterly Report: July-September 2018, Kelsey Duinkerken, Msi, James Copeland, Libt

Jefferson Digital Commons Reports

This quarterly report includes:

  • New Collection Alert
  • Articles
  • Code Red: Battling the Plague of Gun Violence
  • Dissertations
  • From the Archives
  • Grand Rounds and Lectures
  • House Staff Quality Improvement and Patient Safety Posters
  • Journals and Newsletters
  • Nexus Maximus
  • Posters
  • Third Annual Sepsis Symposium
  • What People are Saying



Using Concept Mapping To Develop A Human Rights Based Indicator Framework To Assess Country Efforts To Strengthen Rehabilitation Provision And Policy: The Rehabilitation System Diagnosis And Dialogue Framework (Resyst), Dimitrios Skempes, John L. Melvin, Per Von Groote, Gerold Stucki, Jerome Bickenbach Oct 2018

Using Concept Mapping To Develop A Human Rights Based Indicator Framework To Assess Country Efforts To Strengthen Rehabilitation Provision And Policy: The Rehabilitation System Diagnosis And Dialogue Framework (Resyst), Dimitrios Skempes, John L. Melvin, Per Von Groote, Gerold Stucki, Jerome Bickenbach

Department of Rehabilitation Medicine Faculty Papers

Background: Rehabilitation is crucial for the realization of the right to health and a proper concern of global health. Yet, reliable information to guide rehabilitation service planning is unavailable in many countries in part due to the lack of appropriate indicators. To ensure universal health coverage and meet the central imperative of "leaving no one behind" countries must be able to assess key aspects of rehabilitation policy and provision and monitor how they have discharged their human rights responsibilities towards those most disadvantaged, including people with disability. This article describes the process of developing an expert guided indicator framework to …


Integration Of Therapies In Autistic Children; A Survey Based In Karachi, Pakistan, Masnoon Akhter, Mussarat Ashraf, Adnan Ali, Irum Rizwan, Rehana Rehman Oct 2018

Integration Of Therapies In Autistic Children; A Survey Based In Karachi, Pakistan, Masnoon Akhter, Mussarat Ashraf, Adnan Ali, Irum Rizwan, Rehana Rehman

Department of Biological & Biomedical Sciences

A cross-sectional study was conducted from January to June 2016 on autistic children at the Autism Unit of Dow University of Health Sciences to compare speech therapy, occupational therapy and combination of both for rehabilitation of autistic children in the selected population. A total of 55 children with autism age range from 1-12 years of both gender and all ethnic groups were recruited. All data was analysed in IBM-SPSS version 23.0. Pearson chi-square test was used to determine association of type of therapy with the diagnosed age of child, gender, mode of delivery, history of vaccination and parent's education. Educated …


Designing A Wrist-Worn Sensor To Improve Medication Adherence: Accommodating Diverse User Behaviors And Technology Preferences., Jenna L Marquard, Barry Saver, Swaminathan Kandaswamy, Vanessa I Martinez, Jane M Simoni, Joanne D Stekler, Deepak Ganesan, James Scanlan Oct 2018

Designing A Wrist-Worn Sensor To Improve Medication Adherence: Accommodating Diverse User Behaviors And Technology Preferences., Jenna L Marquard, Barry Saver, Swaminathan Kandaswamy, Vanessa I Martinez, Jane M Simoni, Joanne D Stekler, Deepak Ganesan, James Scanlan

Articles, Abstracts, and Reports

Objectives: High medication adherence is important for HIV suppression (antiretroviral therapy) and pre-exposure prophylaxis efficacy. We are developing sensor-based technologies to detect pill-taking gestures, trigger reminders, and generate adherence reports.

Materials and Methods: We collected interview, observation, and questionnaire data from individuals with and at-risk for HIV (

Results: While participants displayed diverse medication taking practices and physical actions, most (67%) wanted to use the system to receive real-time and summative feedback, and most (69%) wanted to share data with their physicians. Participants preferred reminders via the wrist-worn device or mobile app, and summative feedback via mobile app or email. …


The Bulletin: Sidney Kimmel Medical College At Thomas Jefferson University, Volume 67, Issue 3, Fall 2018 Oct 2018

The Bulletin: Sidney Kimmel Medical College At Thomas Jefferson University, Volume 67, Issue 3, Fall 2018

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

This issue includes:

  • Explaining Uncertainty
  • A Series of Fortunate Events
  • 2018 Alumni Weekend
  • The Dean's Column
  • Findings
  • The Jefferson Legacy
  • Time Capsule
  • On Campus
  • Jefferson Researcher Explores Cell Death Controls and Effects
  • New Alumni Association President
  • Class Notes
  • In Memoriam
  • By the Numbers


Microbiological Testing Of Adults Hospitalised With Community-Acquired Pneumonia: An International Study, Manuela Carugati, Stefano Aliberti, Luis Felipe Reyes, Ricardo Franco Sadud, Muhammad Irfan Oct 2018

Microbiological Testing Of Adults Hospitalised With Community-Acquired Pneumonia: An International Study, Manuela Carugati, Stefano Aliberti, Luis Felipe Reyes, Ricardo Franco Sadud, Muhammad Irfan

Section of Pulmonary & Critical Care

This study aimed to describe real-life microbiological testing of adults hospitalised with community-acquired pneumonia (CAP) and to assess concordance with the 2007 Infectious Diseases Society of America (IDSA)/American Thoracic Society (ATS) and 2011 European Respiratory Society (ERS) CAP guidelines.

This was a cohort study based on the Global Initiative for Methicillin-resistant Staphylococcus aureusPneumonia (GLIMP) database, which contains point-prevalence data on adults hospitalised with CAP across 54 countries during 2015.

In total, 3702 patients were included. Testing was performed in 3217 patients, and included blood culture (71.1%), sputum culture (61.8%), Legionella urinary antigen test (30.1%), pneumococcal urinary antigen test (30.0%), …


Further Evaluation Of The Pls Program: Reduced Consultant Involvement, Kelly Ann Pelletier Psyd Oct 2018

Further Evaluation Of The Pls Program: Reduced Consultant Involvement, Kelly Ann Pelletier Psyd

All Student Scholarship

This study evaluated the effects of the preschool life skills program (PLS; Hanley, Heal, Tiger, & Ingvarsson, 2007) on the acquisition of pro-social skills and reduction of interfering classroom behavior in a public special education pre-school in the Pacific Northwest. The rationale for the current study is based on the reality that consultants and trained assistants may not be a common element available to the average preschool setting. The objective of this investigation was to determine whether gains in pro-social skills and reductions in challenging behavior would occur under conditions of reduced consultant or supervisor involvement in this setting. In …


A Real-World Comparison Of Relapse Rates, Healthcare Costs And Resource Use Among Patients With Multiple Sclerosis Newly Initiating Subcutaneous Interferon Beta-1a Versus Oral Disease-Modifying Drugs., James D Bowen, Chris M Kozma, Megan M Grosso, Amy L Phillips Oct 2018

A Real-World Comparison Of Relapse Rates, Healthcare Costs And Resource Use Among Patients With Multiple Sclerosis Newly Initiating Subcutaneous Interferon Beta-1a Versus Oral Disease-Modifying Drugs., James D Bowen, Chris M Kozma, Megan M Grosso, Amy L Phillips

Articles, Abstracts, and Reports

Background: Administrative-claims data enable comparative effectiveness assessment using large numbers of patients treated in real-world settings.

Objective: To evaluate real-world relapses, healthcare costs and resource use in patients with MS newly initiating subcutaneous interferon beta-1a (sc IFNβ-1a) v. oral disease-modifying drugs (DMDs: dimethyl fumarate, fingolimod, teriflunomide).

Methods: Patients from an administrative claims database (1 Jan 2012-31 Dec 2015) were selected if they: were 18-63 years old; had an MS diagnosis; had newly initiated sc IFNβ-1a, dimethyl fumarate, fingolimod, or teriflunomide (first claim = index); had no evidence of DMD 12-months pre-index; and had 12-month eligibility pre- and post-index. Relapse was …


Aligning Systems Science And Community-Based Participatory Research: A Case Example Of The Community Health Advocacy And Research Alliance (Chara)., Melinda M Davis, Paul Lindberg, Suzanne Cross, Susan Lowe, Rose Gunn, Kristen Dillon Oct 2018

Aligning Systems Science And Community-Based Participatory Research: A Case Example Of The Community Health Advocacy And Research Alliance (Chara)., Melinda M Davis, Paul Lindberg, Suzanne Cross, Susan Lowe, Rose Gunn, Kristen Dillon

Articles, Abstracts, and Reports

Partnered research may help bridge the gap between research and practice. Community-based participatory research (CBPR) supports collaboration between scientific researchers and community members that is designed to improve capacity, enhance trust, and address health disparities. Systems science aims to understand the complex ways human-ecological coupled systems interact and apply knowledge to management practices. Although CBPR and systems science display complementary principles, only a few articles describe synergies between these 2 approaches. In this article, we explore opportunities to utilize concepts from systems science to understand the development, evolution, and sustainability of 1 CBPR partnership: The Community Health Advocacy and Research …


Evaluating The Potential Benefit Of Reduced Planning Target Volume Margins For Low And Intermediate Risk Patients With Prostate Cancer Using Real-Time Electromagnetic Tracking., Avinash R Chaurasia, Kelly J Sun, Christopher Premo, Timothy Brand, Brent Tinnel, Stacie Barczak, John Halligan, Michael Brown, Dusten Macdonald Oct 2018

Evaluating The Potential Benefit Of Reduced Planning Target Volume Margins For Low And Intermediate Risk Patients With Prostate Cancer Using Real-Time Electromagnetic Tracking., Avinash R Chaurasia, Kelly J Sun, Christopher Premo, Timothy Brand, Brent Tinnel, Stacie Barczak, John Halligan, Michael Brown, Dusten Macdonald

Articles, Abstracts, and Reports

Purpose: The aim of this study is to quantify and describe the feasibility, clinical outcomes, and patient-reported outcomes of reduced planning target volume (PTV) margins for prostate cancer treatment using real-time, continuous, intrafraction monitoring with implanted radiation frequency transponder beacons.

Methods and materials: For this prospective, nonrandomized trial, the Calypso localization system was used for intrafraction target localization in 31 patients with a PTV margin reduced to 2 mm in all directions. A total of 1333 fractions were analyzed with respect to movement of the prostate, pauses and interruptions, and dosimetric data. Pre- and posttreatment quality-of-life scores were tracked at …


Manifestations Of Hypomelanosis Of Ito, Ana C. Albuja, Arpan Shrivastava, Gulam Q. Khan Oct 2018

Manifestations Of Hypomelanosis Of Ito, Ana C. Albuja, Arpan Shrivastava, Gulam Q. Khan

Neurology Faculty Publications

No abstract provided.


Champion Teams As A Mechanism For Developing Team Care Capacity, Robert M. Tolliver, Gayatri Jaishankar, Jodi Polaha Oct 2018

Champion Teams As A Mechanism For Developing Team Care Capacity, Robert M. Tolliver, Gayatri Jaishankar, Jodi Polaha

ETSU Faculty Works

"Practice transformation" toward team care as a singular undertaking can be daunting. In this presentation, we describe the development of a mechanism for small, iterative and sustainable practice changes toward team care known as "Champion Teams." Champion Teams are based on the Institute of Medicine's "learning health care system" approach in which practitioners develop an internal mechanism for and culture around digesting and implementing new evidence based practices on an ongoing basis. In addition to presenting the Champion Team concept as a strategy for implementing new team care initiatives, interprofessional providers will present two case examples from each adult and …


Las Perspectivas De Los Trabajadores Sobre La Accesibilidad A Los Recursos Públicos Para El Tratamiento De Depresión Y Ansiedad En La Actualidad En El Área Metropolitana De Buenos Aires: Estudio Cualitativo De Tipo Exploratorio-Descriptivo. / Perspectives Of Workers On The Accessibility Of Public Resources For The Treatment Of Depression And Anxiety In The Metropolitan Area Of Buenos Aires: Qualitative Exploratory-Descriptive Study., Ellen Broaddus Oct 2018

Las Perspectivas De Los Trabajadores Sobre La Accesibilidad A Los Recursos Públicos Para El Tratamiento De Depresión Y Ansiedad En La Actualidad En El Área Metropolitana De Buenos Aires: Estudio Cualitativo De Tipo Exploratorio-Descriptivo. / Perspectives Of Workers On The Accessibility Of Public Resources For The Treatment Of Depression And Anxiety In The Metropolitan Area Of Buenos Aires: Qualitative Exploratory-Descriptive Study., Ellen Broaddus

Independent Study Project (ISP) Collection

En los últimos años, el tema de la salud mental se ha convertido en un elemento fundamental para la salud y el bienestar. Con la ley nacional 26.657 de 2010, Argentina declaró que todos tendrían servicios de salud mental gratuitos y accesibles y que no serían discriminados por sus trastornos. Sin embargo, los trastornos mentales, especialmente la depresión y la ansiedad, siguen siendo muy frecuentes, y en realidad muchos de los recursos públicos prometidos no son en realidad accesibles. Para investigar el estado actual de la salud mental pública, esta investigación buscó en los profesionales del campo para explorar sus …


An Exploratory Study On Mental Illness Perspectives In Hanoi, Margaret Cox Oct 2018

An Exploratory Study On Mental Illness Perspectives In Hanoi, Margaret Cox

Independent Study Project (ISP) Collection

Almost 12 million people in Vietnam have been diagnosed with a mental illness; the prevalence of mental illness within the population means that understanding how people perceive it. Previous research has demonstrated the negative impacts that stigma and negative perceptions of mental illness have and how they can inhibit individuals from seeking treatment for a mental illness. The aim of this exploratory study was to answer the question: How do Vietnamese university students and mental health professionals living in Hanoi perceive mental illness? Fifteen university students and five mental health professionals were interviewed in a series of semi-structured interviews. A …


The Challenges Of India’S Rising Breast Cancer Epidemic, Brigette Stickney Oct 2018

The Challenges Of India’S Rising Breast Cancer Epidemic, Brigette Stickney

Independent Study Project (ISP) Collection

India is currently undergoing rapid urbanization, which is greatly impacting Indian citizens’ health. One of the rising concerns due to the drastic lifestyle and environmental changes that are results of urbanization is the issue of breast cancer. Breast cancer diagnosis rates are rising exponentially, and breast cancer has moved its way up to be the most common cancer in India. Breast cancer mortality rates in India are also some of the worst in the world. This paper analyses the social, mental, economic, geographic, and physical challenges that are present for women diagnosed with cancer in India. It assesses how they …


The Learning Loss Effect In Genetics: What Ideas Do Students Retain Or Lose After Instruction?, Amber Todd, William L. Romine Oct 2018

The Learning Loss Effect In Genetics: What Ideas Do Students Retain Or Lose After Instruction?, Amber Todd, William L. Romine

Biological Sciences Faculty Publications

Modern genetics is a relatively new domain, but it is increasingly important for students to have a firm grasp on the content, because genetic technologies are becoming more commonplace. In a previous study, we used the Learning Progression-based Assessment of Modern Genetics to assess high school students’ knowledge of genetics concepts after an intensive inquiry-based genetics instructional period. Given that this type of intensive inquiry-based instruction is unique, we are now investigating how students’ knowledge of genetics changes after instruction (i.e., learning loss effect). Using a six-measure longitudinal design, we found that students retained significant gains in five of the …


The Lli Chronicle Volume 9 Issue 3, Nova Southeastern University Oct 2018

The Lli Chronicle Volume 9 Issue 3, Nova Southeastern University

Lifelong Learning Institute Newsletters

No abstract provided.


Hss Advocate Departmental Fall 2018, Department Of Health And Sport Sciences Oct 2018

Hss Advocate Departmental Fall 2018, Department Of Health And Sport Sciences

Health and Sport Sciences Newsletter

  • Stand Campaign Results
  • Interested in Study Abroad by Meggin Kelley
  • Fair Play


Hss Advocate Alumni News Fall 2018, Department Of Health And Sport Sciences Oct 2018

Hss Advocate Alumni News Fall 2018, Department Of Health And Sport Sciences

Health and Sport Sciences Newsletter

  • Remembering Our Fallen Officers
  • A Message from the Chair by Dr. Joan Rocks
  • 2018 Bread & Roses Award-Dr. Joan Rocks
  • Dr. Kristy McCray -SARNO Community Partner of the Year for sexual violence prevention work.


Use Of Quantitative Molecular Diagnostic Methods To Investigate The Effect Of Enteropathogen Infections On Linear Growth In Children In Low-Resource Settings: Longitudinal Analysis Of Results From The Mal-Ed Cohort Study, Elizabeth T. Rogawsk, Jie Liu, James A. Platts-Mill, Furqan Kabir, Paphavee Lertsethtakarn, Adil Kalam, Fatima Aziz, Shahida Qureshi, Najeeha Talat Iqbal, Zulfiqar Ahmed Bhutta Oct 2018

Use Of Quantitative Molecular Diagnostic Methods To Investigate The Effect Of Enteropathogen Infections On Linear Growth In Children In Low-Resource Settings: Longitudinal Analysis Of Results From The Mal-Ed Cohort Study, Elizabeth T. Rogawsk, Jie Liu, James A. Platts-Mill, Furqan Kabir, Paphavee Lertsethtakarn, Adil Kalam, Fatima Aziz, Shahida Qureshi, Najeeha Talat Iqbal, Zulfiqar Ahmed Bhutta

Department of Paediatrics and Child Health

Background: Enteropathogen infections in early childhood not only cause diarrhoea but contribute to poor growth. We used molecular diagnostics to assess whether particular enteropathogens were associated with linear growth across seven low-resource settings.
Methods: We used quantitative PCR to detect 29 enteropathogens in diarrhoeal and non-diarrhoeal stools collected from children in the first 2 years of life obtained during the Etiology, Risk Factors, and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) multisite cohort study. Length was measured monthly. We estimated associations between aetiology-specific diarrhoea and subclinical enteropathogen infection and quantity and attained …


Reducing Micronutrient Deficiencies In Pakistani Children: Are Subsidies On Fortified Complementary Foods Cost-Effective?, Simon Wieser, Beatrice Brunner, Christina Tzogiou, Rafael Plessow, Michael B. Zimmermann, Jessica Farebrother, Sajid Bashir Soofi, Zaid Ahmad Bhatti, Imran Ahmed, Zulfiqar Ahmed Bhutta Oct 2018

Reducing Micronutrient Deficiencies In Pakistani Children: Are Subsidies On Fortified Complementary Foods Cost-Effective?, Simon Wieser, Beatrice Brunner, Christina Tzogiou, Rafael Plessow, Michael B. Zimmermann, Jessica Farebrother, Sajid Bashir Soofi, Zaid Ahmad Bhatti, Imran Ahmed, Zulfiqar Ahmed Bhutta

Department of Paediatrics and Child Health

Objective: To estimate the cost-effectiveness of price subsidies on fortified packaged complementary foods (FPCF) in reducing iodine deficiency, iron-deficiency anaemia and vitamin A deficiency in Pakistani children.
Design: The study proceeded in three steps: (i) we determined the current lifetime costs of the three micronutrient deficiencies with a health economic model; (ii) we assessed the price sensitivity of demand for FPCF with a market survey in two Pakistani districts; (iii) we combined the findings of the first two steps with the results of a systematic review on the effectiveness of FPCF in reducing micronutrient deficiencies. The cost-effectiveness was estimated by …


Sex Specific Outcomes In A Substance Use Intervention Program, Alexandra M. Amaducci Do, Ryan A. Anderson Do, Aaron S. Frey Do, Andrew W. Sheen Do, Manuel F. Colón Bs, Paige Roth Msw, Lsw, Crs, Jennifer Stephens Do, Facp, Kevin R. Weaver D.O.,Facoep, David B. Burmeister Do, Mba, Cpe, Facep, Marna R. Greenberg Do, Mph, Facep, Robert D. Cannon Do Oct 2018

Sex Specific Outcomes In A Substance Use Intervention Program, Alexandra M. Amaducci Do, Ryan A. Anderson Do, Aaron S. Frey Do, Andrew W. Sheen Do, Manuel F. Colón Bs, Paige Roth Msw, Lsw, Crs, Jennifer Stephens Do, Facp, Kevin R. Weaver D.O.,Facoep, David B. Burmeister Do, Mba, Cpe, Facep, Marna R. Greenberg Do, Mph, Facep, Robert D. Cannon Do

Department of Emergency Medicine

No abstract provided.


Medical Student Brief Motivational Interviewing For Substance Use In The Emergency Department, Alanna M. Balbi Bs, Anthony E. Gak Ms, Esther S. Kim Ba, Tennessee D. Park Ba, Joann F. Quinn Phd, Mba, Manuel F. Colón Bs, Paige Roth Msw, Lsw, Crs, Kevin R. Weaver Do,Facoep, David M. Richardson Md, Robert D. Cannon Do, Marna R. Greenberg Do, Mph, Facep Oct 2018

Medical Student Brief Motivational Interviewing For Substance Use In The Emergency Department, Alanna M. Balbi Bs, Anthony E. Gak Ms, Esther S. Kim Ba, Tennessee D. Park Ba, Joann F. Quinn Phd, Mba, Manuel F. Colón Bs, Paige Roth Msw, Lsw, Crs, Kevin R. Weaver Do,Facoep, David M. Richardson Md, Robert D. Cannon Do, Marna R. Greenberg Do, Mph, Facep

Department of Emergency Medicine

No abstract provided.


Comparative Success Of A Substance Use Intervention Between Providers, Pratik M. Parikh Do, Erica K. Mason Do, Hillary H. Ward Do, Hanna R. Warren Do, Paige Roth Msw, Lsw, Crs, Manuel F. Colón Bs, David B. Burmeister Do, Mba, Cpe, Facep, Jennifer Stephens Do, Facp, David M. Richardson Md, Marna R. Greenberg Do, Mph, Facep, Robert D. Cannon Do Oct 2018

Comparative Success Of A Substance Use Intervention Between Providers, Pratik M. Parikh Do, Erica K. Mason Do, Hillary H. Ward Do, Hanna R. Warren Do, Paige Roth Msw, Lsw, Crs, Manuel F. Colón Bs, David B. Burmeister Do, Mba, Cpe, Facep, Jennifer Stephens Do, Facp, David M. Richardson Md, Marna R. Greenberg Do, Mph, Facep, Robert D. Cannon Do

Department of Emergency Medicine

No abstract provided.


Reducing Substance Use By An Emergency Department Intervention, Matthew D. Marschall Do, Smeet Bhimani Do, Rachel Fieman Md, Derek J. Fikse Do, Paige Roth Lsw, Jennifer Stephens Do, Manuel F. Colón Bs, Kevin Weaver D.O.,Facoep, David M. Richardson Md, Marna R. Greenberg Do, Mph, Facep, Robert D. Cannon Do Oct 2018

Reducing Substance Use By An Emergency Department Intervention, Matthew D. Marschall Do, Smeet Bhimani Do, Rachel Fieman Md, Derek J. Fikse Do, Paige Roth Lsw, Jennifer Stephens Do, Manuel F. Colón Bs, Kevin Weaver D.O.,Facoep, David M. Richardson Md, Marna R. Greenberg Do, Mph, Facep, Robert D. Cannon Do

Department of Emergency Medicine

No abstract provided.


Oxcarbazepine Overdose In A Polysubstance Related Suicide, Melissa Beals, Robert J. Krumsick, C. Clinton Frazee Iii, Lindsey J. Haldiman, Uttam Garg Oct 2018

Oxcarbazepine Overdose In A Polysubstance Related Suicide, Melissa Beals, Robert J. Krumsick, C. Clinton Frazee Iii, Lindsey J. Haldiman, Uttam Garg

Posters

Introduction
Oxcarbazepine is a derivative of carbamazepine that is used primarily in the treatment of epilepsy, and experimentally as a mood-stabilizer in adjunctive therapy for the treatment of bipolar disorder. Oxcarbazepine is converted through oxidation to its pharmacologically active metabolite 10-OH-Carbazepine, which is thought to be responsible for most of the anticonvulsant action of the drug. Adverse effects of oxcarbazepine are generally dose-dependent and may include fatigue, somnolence, dizziness, diplopia, nystagmus, and ataxia. Additive sedative effects have been noted when oxcarbazepine is used in combination with other CNS depressionproducing medications. Furthermore, oxcarbazepine and 10-OH-Carbazepine are powerful CYP2C19 inhibitors, potentially increasing …


A Curious Case Of Intermittent Left Bundle Branch Block Associated With Cough, Hunaina Shahab, Osman Faheem, Kumail Khandwala, Aamir Hameed Oct 2018

A Curious Case Of Intermittent Left Bundle Branch Block Associated With Cough, Hunaina Shahab, Osman Faheem, Kumail Khandwala, Aamir Hameed

Section of Cardiology

A handful of cases of voluntary control of left bundle branch block (LBBB) have been described in the literature. We report the case of a middle-aged man who was found to have LBBB on baseline electrocardiogram (ECG) which disappeared on coughing and then reappeared with the same maneuver. Subsequent myocardial perfusion scan showed reduced count in the anteroseptal region likely attributed to LBBB. It is possible that the intermittent conduction changes may be due to the alteration in the vagal tone associated with cough as reflected in the change in the PR interval on the ECG.


Outcome Of Radioactive Iodine Therapy In Toxic Nodular Goiter In Pakistan, Tauseef Ahmad, Adeel Khoja, Naveed Rashid, Muhammad Areeb Ashfaq Oct 2018

Outcome Of Radioactive Iodine Therapy In Toxic Nodular Goiter In Pakistan, Tauseef Ahmad, Adeel Khoja, Naveed Rashid, Muhammad Areeb Ashfaq

Section of Cardiology

Objective: To determine the outcome of patients receiving radioactive iodine therapy for toxic nodular goiter coming to Aga Khan University Hospital Karachi.

Methods: A total of 89 patients who visited the outpatient department of Aga Khan University Hospital from January 2010 to August 2017 were recruited for the study. Toxic nodular goiter was diagnosed on the basis of having hot nodule on thyroid scan with low TSH and high FT4/T4. Other demographic and laboratory data were also recorded.

Results: Eighty nine patients with toxic nodular goiter received a dose range from 10 to 30mCi RAI. Six months after RAI, 36.2% …