Medicine and Health Sciences Commons^™

Adult- And Peer-Created Motivational Climates In Sport And Injury Rehabilitation, Rachel Majewski

Dissertations and Theses @ UNI

The motivational climate is the environment, within an achievement setting, created by influential individuals (e.g., coach, athletic trainer, peers) through situational cues, expectations, feedback, and rewards. The way individuals within the setting interpret the motivational climate influences emotions, values, and behaviors which then directly encourages a specific state of participation. Coaches, athletic trainers, and peers need to be aware of the motivational climate they generate and the potentially constructive and detrimental effects on athletes in sport and injury rehabilitation.

The purpose of this study was to examine the relationships between the motivational climate in sport, sport commitment, and injury occurrence. …

The Public's Perceptions Of A Cafe Within The Social And Physical Context Of A Residential Aged Care Facility, Alexa M. Andrew

Internet Journal of Allied Health Sciences and Practice

Background: The publics’ perceptions of aged care residential facilities (ACRF’s) are generally derogatory in nature; with terms such as the ‘end of the road’ or ‘the last resort’ being used to describe them. The institutional design and nature of the traditional ‘nursing home’ has contributed to such a perception. However, more contemporary models of residential aged care facilities are encompassing design features which aim to enhance the physical and social environment and therefore the lives of the older people residing within them.

Purpose: This research reports on the inclusion of a café in the foyer of an aged care residential …

Chapter Three - Neural Correlates Of Sensory Abnormalities Across Developmental Disabilities, Garrett Cardon

Faculty Publications

Abnormalities in sensory processing are a common feature of many developmental disabilities (DDs). Sensory dysfunction can contribute to deficits in brain maturation, as well as many vital functions. Unfortunately, while some patients with DD benefit from the currently available treatments for sensory dysfunction, many do not. Deficiencies in clinical practice surrounding sensory dysfunction may be related to lack of understanding of the neural mechanisms that underlie sensory abnormalities. Evidence of overlap in sensory symptoms between diagnoses suggests that there may be common neural mechanisms that mediate many aspects of sensory dysfunction. Thus, the current manuscript aims to review the extant …

Perceived Treatment Need And Utilization For Illicit Drug And Opioid Use Disorders In Non-Metropolitan Areas, Tyrone F. Borders, Hefei Wen

Rural & Underserved Health Research Center Publications

The policy brief provides nationally representative estimates of perceived treatment need and utilization for illicit drug and prescription pain reliever use disorders among non-metropolitan and metropolitan adults ages 18-64.

Illicit Drug And Opioid Use Disorders Among Non-Metropolitan Residents, Tyrone F. Borders, Hefei Wen

Rural & Underserved Health Research Center Publications

Illicit drug use disorder rates are similar across metropolitan and non-metropolitan areas and did not decline from 2011-2013 to 2014-2015 despite the implementation of major substance use treatment policies over this time period.

Registered Nurses' Experiences Of Passing The Nclex-Rn After More Than One Attempt, Tammy L. Kasprovich, Leona Vandevusse

College of Nursing Faculty Research and Publications

Background:

In the past decade, little research has been conducted regarding individuals' stories about not initially being successful on the National Council Licensure Examination for Registered Nurses. An unsuccessful licensure examination attempt may affect the individual personally and profoundly in ways that could influence their future success.

Method:

Individual in-depth interviews were conducted once with 15 RNs who were initially unsuccessful on the licensure examination and subsequently passed. Data analyses were conducted using both manual and electronic coding through thematic identification. Rigor was ensured by meeting quality criteria for qualitative research.

Results:

Four themes were identified: (a) Pressures all Around, …

Electrode And Headgear Design For Accurate Tdcs, Henry Bernstein

Dissertations and Theses

Stimulating the brain with a low current that is focused on specific regions of the brain has been shown to modify brain function and treat various neurological diseases. Transcranial direct current stimulation (TDCS) has been an effective and life changing alternative treatment for a vast range of neurological conditions including depression, epilepsy, stroke rehabilitation, addiction and chronic pain but only if it is administered correctly. During TDCS, a weak constant current is applied to precise locations on the scalp to modulate brain activity. Those locations can be determined by the cumbersome 10-20 EEG measurement system, transcranial magnetic stimulation or neuronavigation. …

Wnt Secretion Proteins Modulate Rankl-Induced Expression Of Aire In Thymic Epithelial Cells, Daniel Pollack

Dissertations and Theses

Thymic epithelial cells (TEC) are essential for a proper adaptive immune response by regulating thymocyte development and establishing central tolerance. In the thymus, TECs differentially express Wnt proteins, which activate canonical and non-canonical Wnt signaling pathways. Wnt signaling is thought to regulate cell survival, proliferation, and development although the direct molecular mechanisms in TECs have yet to be elucidated. The inducible inhibition of canonical Wnt signaling with Dkk1 leads to a rapid loss of TEC progenitors as well as a decline in mature Aire-expressing mTECs. Therefore, we explore the role of Wnt ligands potentially responsible for stimulating and/or regulating Wnt …

Visits For Depression To Physician Assistants And Nurse Practitioners In The Us, Abiola O. Keller, Roderick S. Hooker, Elizabeth R. Jacobs

College of Nursing Faculty Research and Publications

No abstract provided.

Recertification And Reentry To Practice For Nurse Anesthetists: Determining Core Competencies And Evaluating Performance Via High-Fidelity Simulation Technology, Matthew E. Heyes, Lauren Schnitzen, Deana G. Starr, Charles Vecchiano, Virginia C. Muckler, Lisa Thiemann, J. Frank Titch

College of Nursing Faculty Research and Publications

Introduction

The National Board of Certification and Recertification for Nurse Anesthetistsaddressed a barrier to return to practice of uncertified practitioners by replacing required direct patient care experiences with high-fidelity simulation.

Objectives

The aims of this study were to: (a) validate a set of clinical activities for their relevance to reentry and determine if they could be replicated using simulation, (b) evaluate the content validity of an existing simulation scenario containing the proposed clinical activities and determine its substitutability for a clinical practicum, and (c) evaluate the validity of two methods to assess simulation performance.

Methods

A modified Delphi method …

Health-Related Quality Of Life Of Older Adults In Costa Rica As Measured By The Short-Form-36 Health Survey, Esmeralda Valdivieso-Mora, Mirjana Ivanisevic, Leslie A. Shaw, Mauricio Garnier-Villarreal, Zachary D. Green, Monica Salazar-Villanea, Jose Moncada-Jimenez, David K. Johnson

College of Nursing Faculty Research and Publications

Objective: To test the validity of a common measure of health-related quality of life (Short-Form-36 [SF-36]) in cognitively healthy older adults living in rural and urban Costa Rica. Method: Confirmatory factor analysis was applied to SF-36 data collected in 250 older adults from San Jose and Guanacaste, Costa Rica. Results: The best fitting model for the SF-36 was an eight first-order factor structure. A high correlation between the Mental Component Summary and Physical Component Summary scores was found. Region differences indicated that rural dwellers perceive a poorer health-related quality of life compared with the urban group. Discussion: Costa Rican older …

Factor Structure And Psychometric Properties Of Cognitive-Behavioral Scales In Caregivers Of Persons With Dementia, Abir K. Bekhet, Mauricio Garnier-Villarreal

College of Nursing Faculty Research and Publications

Background/Purpose

Caregiving can be costly to dementia caregivers' well-being. Assessing the factor structure and psychometric properties of Cognitive-Behavioral Scales in dementia caregivers is an essential step in addressing the gap in the current state of research. Specifically, it is essential to determine first whether the factorial structure of the three measures used in this study namely, the Positive Thinking Skills Scale, the Revised Memory and Behavior Problems Checklist, and the Zarit Burden Interview are good representation of the data by studying the good model fit. Next, evaluating the reliability of each factor of the three measures used are essential to …

Teaching Students To Teach Patients: A Theory-Guided Approach, Lori Candela, Linda B. Piacentine, Kathleen L. Bobay, Marianne E. Weiss

College of Nursing Faculty Research and Publications

Nurses in every setting provide patient teaching on a routine basis, often several times a day. Patient teaching skills are essential competencies to be developed during pre-licensure nursing education. While students learn what to teach for specific conditions, they often lack competence in how to teach in ways that individualize and optimize patient learning. The ultimate goal of patient teaching is to arm patients with the knowledge and skills, and the desire and confidence in their ability to reach their targeted health outcomes. We describe the creation of a theoretical framework to guide development of patient teaching skills. The framework, …

Sexual Risk Behaviors Of African American Adolescent Females: The Role Of Cognitive And Religious Factors, Safiya George Dalmida, Natasha Aduloju-Ajijola, Dora L. Clayton-Jones, Tami Thomas, Ricardo J. Erazo Toscano, Rashunda Lewis, Terri Fleming, Shirley Taylor, Macie Lunyong

College of Nursing Faculty Research and Publications

Introduction: African American (AA) high school-age girls are more likely to have had sex before age 13 years and have higher rates of all sexually transmitted infections. Cognition and religion/spirituality are associated with adolescent sexuality, therefore, the purpose of this study was to identify cognitive and religious substrates of AA girls’ risky sexual behaviors. Method: A descriptive study was conducted with 65 AA girls aged 15 to 20 years using computerized questionnaires and cognitive function tasks. Results: Average age was 17.8 ± 1.9 years and average sexual initiation age was 15.5 ± 2.6 years. Overall, 57.6% reported a history of …

Synthesis Of 1,4-Triazolyl Combretacoumarins As Potential Anticancer Agents, Tashrique A. Khandaker

Dissertations and Theses

Coumarins are natural compounds that have various physiological and therapeutic properties, making them pharmacologically important. Combretastatin A-4 (CA-4) is a microtubule-binding agent that has potent cytotoxic effects against human cell lines. In CA-4 the trimethoxyarene moiety plays a crucial role in its carcinopreventive effect. Thus, we decided to synthesize novel, potential anti-cancer agents called 1,4-triazolyl combretacoumarins, by coupling different coumarins and the functionally relevant group of CA-4 i.e, the trimethoxyarene moiety, via a 1,2,3-triazolyl ring using a copper-catalyzed [3 + 2] azide-alkyne cycloaddition (CuAAC) reaction, which is a very atom-economical reaction. The coupling partners, 4-azidocoumarins, required for making these …

Knockdown Of Heparan Sulfate Via Ndst1 Knockout Does Not Inhibit Mouse Aortic Endothelial Cell Alignment In-Vivo, John Diaz De Leon Iii

Dissertations and Theses

Atherosclerotic plaque localizes in predictable areas such as arches and bifurcations which are characterized by disturbed flow patterns and the resulting damage and dysfunction to the endothelium. Endothelial cells (ECs) under sustained laminar flow align in the direction of flow; however, under disturbed flow conditions, ECs sustain damage to their glycocalyx (GCX) which results in unaligned and rounder cells. An investigation into the role of NDST1 sulfation of heparan sulfate (HS), a key component of many proteoglycans which make up the GCX, was conducted. The descending aortas (DAs) of transgenic mice with conditional knockouts (KOs) of NDST1 in vascular ECs …

Proactive Social Validation Of Methods And Procedures Used For Training Speech Production In Aphasia, Tyson G. Harmon, Lucy Hardy, Katarina L. Haley

Faculty Publications

Background: Social validation evaluates the importance and acceptability of treatment goals, procedures, and outcomes. Previous studies for treatments that train speech production in aphasia have applied social validation during the post-treatment period or to treatment protocols that are already fully developed.

Aims: The purposes of this study were to (1) examine the social validity of goals and procedures experienced in speech production treatment for people with aphasia and (2) evaluate the feasibility of procedural choice-making during such tasks.

Method: Seven people with aphasia and eight speech-language pathologists were interviewed about previous treatment that targeted speech production. Participants were also observed …

A Bronchiolitis Study: The Overuse Of Bronchiolitis Therapies In Children Admitted Into The Hospital, Jocelyn S. Canedo

Theses and Dissertations

Bronchiolitis is prevalent among infants of 0 to 12 months, and usually caused by a variation of viruses. Signs and symptoms consist of coughing, rapid breathing, and an occasional fever in some infants. Bronchiolitis is not treated with antibiotics, but rather with proper medical examination and other procedures. Chest radiographs, steroids, and certain bronchodilators are considered ineffective treatments. This study identified the amount of ineffective procedures being used in infants admitted into the pediatric emergency room, and the effect it had on the patient’s average hospital stay. Past medical records were used in this clinical study. Statistical analyses and graphs …

Measuring Leak Rates From Abandoned Natural Gas Wells In Western Pennsylvania, John Bradshaw, Jeremy M. Slagley, Nicole Iannacchione, Matthew Lees

Faculty Publications

The proliferation of unconventional natural gas drilling has brought considerable recent attention to the possible impacts that this new technology may have on greenhouse gas emissions. In Pennsylvania, estimates of these possible impacts are very difficult to accurately assess in large part due to the highly uncertain contribution from legacy abandoned and orphaned gas (AOG) wells. This paper outlines our work in establishing a methodology for measuring the methane leak rate from AOG wells in Western Pennsylvania. The theory and methodology of an enclosure method for measuring the methane mass leak rate from one AOG natural gas well is described. …

The Effect Of Fast Food Restaurants On Type 2 Diabetes Rates, Grace Bailey

CMC Senior Theses

This paper conducts an analysis of county level data to determine the effect of fast food restaurants on type 2 diabetes rates. Due to endogeneity concerns with respect to the location of fast food restaurants, this paper follows the work of Dunn (2010) and uses the number of interstate exits in a given county to serve as an instrument for fast food restaurants. The strength of the instrument, which is theoretically and empirically tested in this paper, imposes some restraints on the interpretation of the findings. Using the Two-Stage Least Squares estimation method, I find that the presence of fast …

Ccl11 As A Biomarker For The In Vivo Diagnosis Of Chronic Traumatic Encephalopathy, Robert Weissenfels

CMC Senior Theses

Chronic traumatic encephalopathy is the neurodegenerative disease that is ascribed to the long term development of cognitive, behavioral, emotional, and motor deficits as a result of the exposure to high amounts of sub concussive traumatic brain injuries. The disease has gained recent popularity in the media for its prevalence in American football as a response to recent research that has suggested the prominence of the disease in nearly every NFL player that is examined post mortem. This has produced a growing concern for the consequences of head impact and participation in contact sports. Despite media attention, little is currently known …

Hyperthermia As A Cancer Treatment- From Theory To Practice, Graham Fullerton

CMC Senior Theses

Using iron super-paramagnetic and ferromagnetic nanoparticles composed of Fe₃O₄ molecules, scientists analyze the effectiveness and practicality of this new treatment theory, hyperthermia. The problems of magnetic particle density, isothermal barriers/cellular cooling thresholds, and nanoparticle specific targeting are addressed in this review.

Iron magnetic nanoparticles were chosen due to their relatively low biological reactivates and lack of subsequent cellular toxicity. However, there are significant heating problems associated with these magnetic nanoparticles due to their relative size and short thermal time constants or thermal half-lives. Effectively, these aforementioned issues create a phenomenon where cancerous cells, surrounded by unheated healthy …

Crispr-Cas9 Mediated Hmgcl Ko In 3xtg Ad Mice Reduces The Cognitive Deficit Improvement Seen In An Intermittent Metabolic Switching Regimen, Eric Joon Bum Kil

CMC Senior Theses

Individuals in modern Western societies are experiencing increasing sedentary lifestyles, overindulgence of high fat, high-sugar diets, and extremely sterilized conditions, putting immense pressure on researchers and clinicians alike to come up with viable treatments for conditions implicated with an aging society. Emerging research have published the benefits of IMS and metabolic switching in a variety of neuroprotective, cellular stress resistance, and neuroplasticity pathways in animal models and clinical results from randomized trials of IMS regimens with susceptible human populations are soon to be published. The application of genome editing and next-generation sequencing (NGS) strategies to clinical and neurodegenerative research continues …

The Balance Between Financial And Quality Performance In For-Profit Hospitals Versus Non-Profit Hospitals, Blake Seidner

CMC Senior Theses

Recent trends of financial distress for non-profit hospitals and the uptick in acquisition of these hospitals by for-profit entities indicate different focuses from the management of each type of hospital. Using data on hospital quality and basic financial measures, this study examines shift in the balance of financial and quality performance. The dataset focuses on private non-profit and for-profit hospitals with low bed counts, ranging from 50-200 total beds. Results indicate a positive relationship between for-profit status and basic financial performance measures, such as profitability, and a negative relationship with patient experience, cost reduction for the patient, and overall quality. …

Cultural Adaptation To Suicide Prevention Interventions On College Campuses, Leisha Marie Chiles

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

Suicide is the second leading cause of death for adolescents and young adults ages 15 to 34. Given that college students are within that age range, it is believed they are at a similar risk. As college campuses try to address the suicide risk among their diverse student body, many have developed a public health approach, including the use of gatekeeper trainings. Many of these population-based interventions take a one-size fits all approach to suicide prevention, but with an increasingly diverse student population represented on college campuses this type of approach may fall short and fail to meet the cultural …

Six-Month Post-Release Outcomes For Inmates With Traumatic Brain Injury In Supported Community Programming, Elizabeth O. Ahlers

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

Traumatic brain injury (TBI) is a serious public health issue. The incidence of TBI is much higher in the incarcerated population than in the general population, making this a uniquely vulnerable population. Methods: This study looks at data from the Jail Based Behavioral Health Services (JBBS) to examine recidivism rates among inmates participating in supportive programming. It also uses data from a state brain injury program to examine the impact of case management on community engagement in the justice-involved population with a history of brain injury. Results: Statewide data for a population of inmates who elect to participate …

The Effects Of Recreational Marijuana Legislation On The Opioid Epidemic In Washington State, Steven Dickerson

CMC Senior Theses

This paper analyzes the impact of the 2012 legalization of recreational marijuana in Washington State on opioid abuse. Using synthetic control methodology, this paper finds that the legislation prevented 638 overdose deaths and lead to over 3,600 individuals seeking treatment for opioid abuse disorders. Due to the large health, social, and economic impacts of the opioid epidemic, further research should be conducted into ways to reduce the number of opioid prescriptions, the number of opioid overdoses, and opioid abuse generally.

Mental Health In U.S. Prisons: How Our System Is Set Up For Failure, Katherine Daifotis

CMC Senior Theses

During the past 60 years, United States prisons have become one of the primary institutions caring for mentally ill individuals. Factors such as privatization of mental health care with a focus on profit-maximization, ineffective jail diversion programs, and unsuccessful mental health courts have contributed to prisons having an increased population of mentally ill inmates. In fact, about 20% of people who are currently incarcerated suffer from a major mental illness (Mason, 2007). Other elements outside of the justice system such as a lack of mental health awareness and a lack of resources have led to damaging interactions between the mentally …

A Link Between Gut Microbes & Depression: Microbial Activation Of The Human Kynurenine Pathway, Christina Cobb

CMC Senior Theses

Our gut microbiota is involved in human development, nutrition, and the pathogenesis of gut disorders, but has more recently been implicated as a possible mechanism in the pathophysiology of several brain disorders, including disorders of mood and affect, such as depression. Researchers have referred to this dynamic, bidirectional signaling pathway between the gut and the brain as the “gut-brain axis.” However, most research on this axis has been limited to rodent studies, and there has been little insight into the mechanism behind it. I propose that the kynurenine pathway, where tryptophan is converted to kynurenine, is a compelling mechanism mediating …

Speech Adaptation To Kinematic Recording Sensors: Perceptual And Acoustic Findings, Christopher Dromey, Elise Hunter, Shawn L. Nissen

Faculty Publications

Purpose

This study used perceptual and acoustic measures to examine the time course of speech adaptation after the attachment of electromagnetic sensor coils to the tongue, lips, and jaw.

Method

Twenty native English speakers read aloud stimulus sentences before the attachment of the sensors, immediately after attachment, and again 5, 10, 15, and 20 min later. They read aloud continuously between recordings to encourage adaptation. Sentence recordings were perceptually evaluated by 20 native English listeners, who rated 150 stimuli (which included 31 samples that were repeated to assess rater reliability) using a visual analog scale with the end points labeled …