Medicine and Health Sciences Commons^™

Bisphenol A Exposure And Cardiac Electrical Conduction In Excised Rat Hearts, Nikki G. Posnack, Rafael Jaimes Iii, Huda Asfour, Luther Swift, Anastasia M. Wengrowski, Narine Sarvazyan, Matthew Kay

Pharmacology and Physiology Faculty Publications

BACKGROUND:

Bisphenol A (BPA) is used to produce polycarbonate plastics and epoxy resins that are widely used in everyday products, such as food and beverage containers, toys and medical devices. Human biomonitoring studies have suggested that a large proportion of the population may be exposed to BPA. Recent epidemiological studies have reported correlations between increased BPA urinary concentrations and cardiovascular disease; yet the direct effects of BPA on the heart are unknown.

OBJECTIVES:

The goal of our studies was to measure BPA's effect (0.1-100 μM) on cardiac impulse propagation ex vivo, using excised whole hearts from adult rats.

METHODS: …

The Edward Bliss Emerson Journal Project: Qualitative Research By A Non-Hierarchical Team, José G. Rigau-Pérez, Silvia E. Rabionet, Annette B. Ramírez De Arellano, Wilfredo A. Géigel, Alma Simounet, Raúl Mayo-Santana

The Qualitative Report Books

Edward Bliss Emerson (1805-1834), a younger brother of the renowned essayist and poet Ralph Waldo Emerson, lived in the Caribbean for the final three years of his life. His journal and letters are a rich manuscript source for the history of the Danish Virgin Islands (1831-1832) and Puerto Rico (1831-1834). The texts also reflect the contemporary political and cultural situation in the United States, and Edward's search for health, economic independence, intellectual stimulation and metaphysical fulfillment.

These writings ignited an intellectual passion in José G. Rigau-Pérez, a physician, medical epidemiologist, and historian in Puerto Rico. Furthering access to these unique …

Marshall University Joan C. Edwards School Of Medicine, Professional Enhancement Newsletter, Spring 2014, Darshana Shah Ph.D

Professional Enhancement News (PEN)

Spring 2014, Volume 6, Number 1

Implementation Of A Mhealth Program Within A Homeless Population Of Young Mothers, Maureen Byrnes

Seton Hall University DNP Final Projects

Purpose: Despite major medical advancements and education, more than 500,000 babies are born prematurely and an estimated 28,000 infants die before their first birthday annually (www.marchofdimes.com/peristats). New Jersey’s infant mortality rate appears exemplary when compared to the United States overall infant mortality rate. Yet, New Jersey’s infant mortality rate, preterm birth rate and low birth rate by mother’s race reveal a far greater risk for infants born to a mother who is African American (www.nj.gov/health/epht/outcome.shtml). The need for innovative approaches to improving New Jersey’s maternal-infant health is paramount. Mobile phones may provide an appropriate means of …

Characterization Of A Far-Red Analog Of Ghrelin For Imaging Ghs-R In P19-Derived Cardiomyocytes., Gregory A F Douglas, Rebecca Mcgirr, Carlie L Charlton, Dov B Kagan, Lisa M Hoffman, Leonard G Luyt, Savita Dhanvantari

Medical Biophysics Publications

Ghrelin and its receptor, the growth hormone secretagogue receptor (GHS-R), are expressed in the heart, and may function to promote cardiomyocyte survival, differentiation and contractility. Previously, we had generated a truncated analog of ghrelin conjugated to fluorescein isothiocyanate for the purposes of determining GHS-R expression in situ. We now report the generation and characterization of a far-red ghrelin analog, [Dpr(3)(octanoyl), Lys(19)(Cy5)]ghrelin (1-19), and show that it can be used to image changes in GHS-R in developing cardiomyocytes. We also generated the des-acyl analog, des-acyl [Lys(19)(Cy5)]ghrelin (1-19) and characterized its binding to mouse heart sections. Receptor binding affinity of Cy5-ghrelin as …

Avoid, Accommodate, Confront Or Collaborate: Using Simulation To Teach Conflict Resolution Skills, E. Adel Herge, Otd, Otr/L, Deborah A. Hopkins, Ms, Otr/L

Department of Occupational Therapy Posters and Presentations

Objective:

• Interprofessional education competencies include understanding roles & responsibilities of team members, and demonstrating effective communication and team building skills (Pardue, 2013).
• Team conflict impacts patient safety and outcomes (Knickle & McNaughton, 2009; Wagner, Liston & Miller, 2011) so effective team communication and conflict resolution in an important skill for students to develop (Greer et al., 2012; Levi, 2014).
• Simulation is effective in teaching interprofessional communication skills to health profession students (Velde, 2009).

Education Through Recreation, Vivian Mcalister

Data and Test Instruments

The concept of education through recreation was first applied in the 19th century to childhood develop ment. George H. Read, the Chicago sociologist who identified the developmental role of play in childhood, divided human activity into 3 general types: work, art and play. The principle was broadened to include young adults, but the emphasis was restricted to phys - ical activities. It was the basis for the rise of organized sports and initiatives such as the Olympic Games. Another Chicago sociologist, Nels Anderson, who spent a considerable part of his career at the University of New Brunswick, developed the concept …

L’Éducation Par Les Loisirs, Vivian Mcalister

Data and Test Instruments

Le concept de l’éducation par les loisirs a été appliqué pour la première au 19e siècle au développement de l’en fant 2 . George H. Read, sociologue de Chicago qui a identi fié le rôle du jeu dans le développement de l’enfant, avait divisé l’activité humaine en 3 grandes catégories : travail, art et jeu 2 . Le principe a été élargi pour inclure les jeunes adultes, mais l’accent était limité aux activités physiques 3 . Cette façon de penser a été à la base de la croissance des sports organisés et des initiatives telles que les Jeux olympiques. Un …

Do Body Image Investment And Evaluation Relate To Bulimic Symptoms In U.S. Collegiate Men And Women In The Same Way?, Mary E. Pritchard

Psychological Sciences Faculty Publications and Presentations

Although research suggests that body image investment (i.e., drive for muscularity, orientation toward appearance, preoccupation with weight or weight gain) and body image evaluation factors (e.g., negative evaluations of appearance, overestimation of current weight) correlate with bulimic symptoms, the magnitude of these relationships may differ between men and women. The relationship between bulimic symptoms and the drive for muscularity, one form of body image investment theorized to be particularly relevant to men, is understudied in college students. This study examined bulimic symptoms, body image investment, and body image evaluation in American undergraduate students (84 men, 198 women). Bulimic symptoms were …

Alumni Journal - Volume 85, Number 1, Loma Linda University School Of Medicine

Alumni Journal, School of Medicine

Features
8 | Those Who Came Before Us: Celebrating the 100th Anniversary of the First Six Graduates
12 | APC 2014
22 | Portraits of Rural Medicine: Past to Present
30 | Cambodia: Teaching Grounds

News
4 | School of Medicine News
32 | Alumni in the News
33 | In Memoriam

Editorial
2 | Bridging the Divide

From the Dean
6 | Remembering our Roots

Interview
18 | The Anatomy of a Disaster: An Interview with Dr. Tamara L. Thomas '87

Historial Snapshot
40 | The Physician's Desk

What's Up Doc?
41 | Dr. Kaarsten Lang '87

Implementation Of A Four Year Rehabilitation Curriculum For Medical Students, Nethra S. Ankam, Md

Department of Rehabilitation Medicine Faculty Papers

In 2009 the Vice-Dean of Undergraduate Medical Education modified the 4th year curriculum by eliminating the required clerkship in Rehabilitation Medicine, and the Department was tasked with the creation of a four year curricular thread. While disappointing, this was a blessing in disguise. For years, we attempted to fit a great deal of content into an ever decreasing timespan, to increasingly disinterested students. Our teachers were also burned out with the sheer volume of students.

Through collaboration with other course directors, we inserted content where it fit the developmental needs of the students. We were also able to introduce students …

Who Are You Going To Call? Primary Care Patients’ Disclosure Decisions Regarding Direct–To–Consumer Genetic Testing, Katherine Wasson, Sara Cherny, Tonya Nashay Sanders, Nancy S. Hogan, Kathy J. Helzlsouer

Nursing: School of Nursing Faculty Publications and Other Works

Background: Direct–to–consumer genetic testing (DTCGT) offers risk estimates for a variety of complex diseases and conditions, yet little is known about its impact on actual users, including their decisions about sharing the information gleaned from testing. Ethical considerations include the impact of unsolicited genetic information with variable validity and clinical utility on relatives, and the possible burden to the health care system if revealed to physicians. Aims: The qualitative study explored primary care patients’ views, attitudes, and decision making considerations regarding DTCGT. This article focuses on the disclosure decisions participants made regarding participation, testing, and results of DTCGT, a topic …

The Fda Funding Crisis, Judith Alphonse, Sireesha Bellam, Marlene Fernandez, Anishka Gilbert, Lauren Roper, Antonia Zapantis, Robert C. Speth

HPD Articles

The role of the Food and Drug Administration (FDA) is to ensure the safety of prescription and nonprescription drugs, dietary supplements, and the food supply, representing more than 20% of US consumer spending. The increased need to monitor imported drugs, drug products and foods, drug shortages, and compounding pharmacies bring the adequacy of FDA funding into question. Performing even at status quo cannot be accomplished if responsibilities increase without equitable funding increases: both from the federal government and fees imposed on FDA-regulated industries. Additionally, scientific advancement, new legislation, and new industries are continually increasing the FDA workload, necessitating commensurate budget …

Summary Of Pediatric Quality Measures For Children Enrolled In Mainecare Ffy 2009-Ffy 2013, Mary Lindsey Smith Phd, Msw

Population Health & Health Policy

In Maine, a key objective of the IHOC CHIPRA demonstration grant is to collect and report on the Initial Core Set of Children’s Health Care Quality Measures (referred to as the “CHIPRA Core Measures”), a set of 24 standardized, evidence-based measures identified by CMS for use by State Medicaid and CHIP programs. This report presents the results of the 18 CHIPRA Core Measures that were collected using MaineCare claims, Vital Statistics or survey data and reported to the Centers for Medicare and Medicaid Services (CMS) for FFY 2013. Also included in this report are an additional three measures from the …

The Impact Of Salsalate Treatment On Serum Levels Of Advanced Glycation End Products In Type 2 Diabetes., Joshua I Barzilay, Kathleen A. Jablonski, Vivian Fonseca, Steven E Shoelson, Allison B Goldfine, Christopher Strauch, Vincent M Monnier, Tinsal-T2d Research Consortium.

GW Biostatistics Center

OBJECTIVE Salsalate is a nonacetylated salicylate that lowers glucose levels in people with type 2 diabetes (T2D). Here we examined whether salsalate also lowered serum-protein-bound levels of early and advanced glycation end products (AGEs) that have been implicated in diabetic vascular complications. RESEARCH DESIGN AND METHODS Participants were from the Targeting Inflammation Using Salsalate for Type 2 Diabetes (TINSAL-T2D) study, which examined the impact of salsalate treatment on hemoglobin A1c (HbA1c) and a wide variety of other parameters. One hundred eighteen participants received salsalate, 3.5 g/day for 48 weeks, and 109 received placebo. Early glycation product levels (HbA1c and fructoselysine …

Genetic Risk Of Progression To Type 2 Diabetes And Response To Intensive Lifestyle Or Metformin In Prediabetic Women With And Without A History Of Gestational Diabetes Mellitus., Shannon D Sullivan, Kathleen A. Jablonski, Jose C Florez, Dana Dabelea, Paul W Franks, Sam Dagogo-Jack, Catherine Kim, William C Knowler, Costas A Christophi, Robert Ratner, Diabetes Prevention Program Research Group.

GW Biostatistics Center

OBJECTIVE The Diabetes Prevention Program (DPP) trial investigated rates of progression to diabetes among adults with prediabetes randomized to treatment with placebo, metformin, or intensive lifestyle intervention. Among women in the DPP, diabetes risk reduction with metformin was greater in women with prior gestational diabetes mellitus (GDM) compared with women without GDM but with one or more previous live births.

RESEARCH DESIGN AND METHODS We asked if genetic variability could account for these differences by comparing β-cell function and genetic risk scores (GRS), calculated from 34 diabetes-associated loci, between women with and without histories of GDM.

RESULTS β-Cell function was …

Metabolic Syndrome Components And Their Response To Lifestyle And Metformin Interventions Are Associated With Differences In Diabetes Risk In Persons With Impaired Glucose Tolerance, H. Florez, M. Temprosa, Trevor J. Orchard, Kieren J. Mather, Santica M. Marcovina, Elizabeth Barrett-Connor, Edward Horton, C. D. Saudek, F. X. Pi-Sunyer, R. E. Ratner, R. B. Goldberg

GW Biostatistics Center

Aims

To determine the association of metabolic syndrome (MetS) and its components with diabetes risk in participants with impaired glucose tolerance (IGT), and whether intervention-related changes in MetS lead to differences in diabetes incidence.

Methods

We used the National Cholesterol Education Program/Adult Treatment Panel III (NCEP/ATP III) revised MetS definition at baseline and intervention-related changes of its components to predict incident diabetes using Cox models in 3234 Diabetes Prevention Program (DPP) participants with IGT over an average follow-up of 3.2 years.

Results

In an intention-to-treat analysis, the demographic-adjusted hazard ratios (95% confidence interval) for diabetes in those with MetS (vs. …

Contact Point, Arthur A. Dugoni School Of Dentistry

Contact Point

No abstract provided.

Medicine + Health, Spring 2014, George Washington University, School Of Medicine And Health Sciences, Office Of Communications And Marketing

Medicine + Health Magazine

No abstract provided.

Annual Report 2013, Forum Staff

National Health Policy Forum

This annual report describes the activities of the Forum during the 2013 calendar year, and provides a snapshot of our participants and resources.

Effect Of Noise On Transient-Evoked Otoacoustic Emissions And Pure-Tone Screening Audiometry, Laura Annette Wade

Doctoral Dissertations

Currently, the American Speech-Language Hearing Association (ASHA) recommends pure-tone audiometry as the preferred audiometric screening method of school-aged children; however, background noise is often present and can result in high referral rate. The current study's goal was to examine the effect of noise on the pass rate on transient-evoked otoacoustic emissions (TEOAEs) and pure-tone audiometric screening measures. Twenty normal hearing adults (M = 22.85), eighteen females and two males, were screened with TEOAEs and pure-tone audiometry in quiet and in different levels of noise (i.e., 40 dB SPL, 50 dB SPL, 60 dB SPL) in a sound-treated booth.

Pure-tone audiometry …

Septic Arthritis Of The Shoulder In A Dental Patient - A Case Report And Review, Elana Dolin Dmd, Leigh D. Perlmutter Dmd, Stuart L. Segelnick Dds, Mea A. Weinberg Dmd, Robert Schoor Dds

Individual Scholarship

Septic arthritis of the glenohumoral joint is rare following dental procedures, comprising approximately 3% of all joint infections. Septic arthritis following bacteremia from dental procedures is uncommon and generally occurs in prosthetic joints. Predisposing causes may include immunocompromising diseases such as diabetes, HIV infection, renal failure and intravenous drug abuse. We report a rare case of unilateral glenohumoral joint septic arthritis in a 60-year-old male patient (without a prosthetic joint) secondary to a dental procedure. The insidious nature of the presentation is highlighted. Septic arthritis infections, though rare, require a high level of clinical suspicion. Vague symptoms of shoulder pain …

A Rare Case Of Myasthenia Gravis With Coexisting Muscular Dystrophy, Sommayya Aftab, M Haroon Hamid, Tipu Sultan

Pakistan Journal of Neurological Sciences (PJNS)

Myasthenia gravis (MG) is an autoimmune disease in which antibodies are directed against postsynaptic membrane of neuromuscular junction, resulting in muscle weakness and fatigability. We report a rare case of an 11 years old boy who was a known case of myasthenia gravis presented with progressive weakness and wasting of facial and limb musculature and was found to have coexisting muscular dystrophy most like facioscapulohumeral muscular dystrophy (FSHD).

Estimating Child Sleep From Parent Report Of Time In Bed: Development And Evaluation Of Adjustment Approaches, Timothy D. Nelson, Alyssa Lundahl, Dennis L. Molfese, Rachel N. Waford, Adrienne Roman, David Gozal, Victoria J. Molfese, Melissa C. Ferguson

Department of Psychology: Faculty Publications

Objective To develop and evaluate adjustment factors to convert parent-reported time in bed to an estimate of child sleep time consistent with objective measurement. Methods A community sample of 217 children aged 4–9 years (mean age = 6.6 years) wore actigraph wristwatches to objectively measure sleep for 7 days while parents completed reports of child sleep each night. After examining the moderators of the discrepancy between parent reports and actigraphy, 3 adjustment factors were evaluated. Results Parent report of child sleep overestimated nightly sleep duration by ~24 min per night relative to actigraphy. Child age, gender, and sleep quality all …

Pelaksanaan Program Children Educational Support Dalam Mengurangi Prevalensi Anak Jalanan Oleh Yayasan Indonesian Street Children Organisation (Isco) : Studi Deskriptif Di Sanggar (Isco) Kelurahan Kebun Melati, Tanah Abang, Wirda Amalia, Dwi Amalia Chandra Sekar

Jurnal Ilmu Kesejahteraan Sosial

This article discusses about the implementation of children educational support in reducing prevelance of street children by ISCO Foundation. Motivated by many poor children vulnerable to be street cause the difficulty of access to educational services. This research used a qualitative approach. Collecting data using observation and interview with 9 informant. The study results show that implementation of program has already ran fairly well characterized by reduced child beneficieris who took the streets due to provision of assistance in formal and non-formal education. This made the fulfillment of poor children needs to get an education from early age so the …

Let's Talk Speech! Volume 7 Issue 1, Barbara T. Schmidt Ph.D.

Communication Sciences and Disorders Newsletter

The 2013-2014 academic year has been filled with memorable events. As you read, I think you will get a sense of how our department has grown and how many things we are grateful for. First, this academic year brought us 20 new graduate students to add to the 19 we already had. Students coming from approximately 16 different undergraduate programs have filled the halls with activity. The clinical educators, faculty and staff welcomed all of them and have enjoyed working with them. We will be reluctant to see our 2 nd year students leave us in May, but we look …

J Am Coll Dent 2014 81 2

Journal of the American College of Dentists

The Journal of the American College of Dentists (JACD) publishes scholarly articles, editorials, essays, and reflections addressing the ethical, professional, and social dimensions of dentistry. The Journal serves as a forum for advancing ethics, professionalism, leadership, and excellence within the dental community. By fostering dialogue across disciplines and perspectives, JACD provides readers with insights that encourage ethical, professional practice, lifelong learning, and service to the public, reinforcing dentistry’s commitment to advancing oral healthcare and the common good.

Translational Nutrition: A Review Of The Application Of Nutrition Science, Regulation, And Outreach Case Study: Farm Fresh Rhode Island, Eliza Zalis

Public & Community Service Studies Student Scholarship

This project examines the avenues by which nutrition science impacts individuals in society. It examines the factors that influence consumer behavior and food choice and the importance of health literacy in guiding nutrition and health. It elucidates the role of the Food and Drug Administration (FDA) in regulating food labeling and the implications that such regulation has on consumer perception and possible health outcomes. Further, this project outlines recently proposed changes to the “Nutrition Facts” panel. In investigating nutrition education and outreach programs, this project includes a case study of Farm Fresh Rhode Island and the organization’s nutrition initiatives.

Program And Proceedings: Nebraska Academy Of Sciences 1880–2014, 134th Anniversary Year, One Hundred-Twenty-Fourth Annual Meeting, April 11, 2014

Nebraska Academy of Sciences: Programs and Proceedings

Program

Aeronautics and Space Science

Collegiate Academy: Biology

Chemistry and Physics

Collegiate Academy: Chemistry and Physics

Applied Science and Technology

Biological and Medical Sciences

Aeronautics and Space Science, Poster Session

Anthropology

Maiben Memorial Lecture: "Education, Careers and Opportunities in Engineering and Metallurgy in Nebraska," Terry Rasmussen, Nucor Steel, Norfolk, Nebraska

Teaching of Science and Mathematics

Anthropology

Earth Science

Bridging The Evidence Gap: The Role Of Fieldwork Students, Tracey Vause-Earland, Ms, Otr/L, E. Adel Herge, Otd, Otr/L, Faota

Department of Occupational Therapy Posters and Presentations

Introduction

Understanding and using evidence in practice improves health care delivery (Lugtenberg, Burgers, & Westert, 2009), reduces errors, and increases professional identity. Despite the call for increased use of evidence in occupational therapy decision making and positive attitudes of therapists toward use of evidence in practice), evidence based practice (EBP) is perceived by clinicians as time consuming and difficult due to lack of knowledge and/or resources (Humphries, et al, 2000; Bennett et al, 2003).