Medicine and Health Sciences Commons^™

Draft Genome Sequence Of Acetobacter Aceti Strain 1023, A Vinegar Factory Isolate, John Hung, Christopher Mill, Sandra Clifton, Vincent Magrini, Ketaki Bhide, Julie Francois, Aaron Ransome, Lucinda Fulton, Jyothi Thimmapuram, Richard Wilson, T. Joseph Kappock

Cyber Center Publications

The genome sequence of Acetobacter aceti 1023, an acetic acid bacterium adapted to traditional vinegar fermentation, comprises 3.0 Mb (chromosome plus plasmids). A. aceti 1023 is closely related to the cocoa fermenter Acetobacter pasteurianus 386B but possesses many additional insertion sequence elements.

Refugee Health In Montgomery County: A Retrospective Descriptive Study Of Refugee Health Screening Results From April 2007 - April 2008, Marjan Lyons

Master of Public Health Program Student Publications

Introduction: The top refugee health concerns characteristically are associated with parasitic infections, infectious diseases such as malaria, tuberculosis, and parasites, as well as nutritional deficiencies such as anemia, and malnourishment. Understanding the specific health needs of the refugee population will not only improve the transition of the refugees within the United States healthcare systems, but also improve public health within the community.

Methods: Health records from Public Health - Dayton & Montgomery Country were used to obtain the prevalence of both acute and chronic health conditions within the newly resettled refugee population. There were a total of 193 refugees included …

Characterization Of Methylene Diphenyl Diisocyanate Protein Conjugates, Morgen Mhike

Dissertations and Theses

Diisocyanates (dNCO) such as methylene diphenyl diisocyanate (MDI) are used primarily as cross-linking agents in the production of polyurethane products such as paints, elastomers, coatings and adhesives, and are the most frequently reported cause of chemically induced immunologic sensitization and occupational asthma (OA). Immune mediated hypersensitivity reactions to dNCOs include allergic rhinitis, asthma, hypersensitivity pneumonitis and allergic contact dermatitis.

There is currently no simple diagnosis for the identification of dNCO asthma due to the variability of symptoms and uncertainty regarding the underlying mechanisms. Immunological sensitization due to dNCO exposure is traditionally thought to require initial conjugation of the dNCO to …

Participation, Information, Values, And Community Interests Within Health Impact Assessments, Nicole Iroz-Elardo

Dissertations and Theses

Health impact assessment (HIA) has emerged in the U.S. as one promising process to increase social and environmental justice through addressing health equity issues within planning. HIA practice is guided by values such as democracy and equity and grounded in broad social determinants of health. The most readily applied definition of democracy is problematic because it implies an element of direct, participatory engagement with the public. This is at odds with HIA practice that largely relies on stakeholder engagement strategies.

This dissertation critically examines the engagement strategies of three transportation planning HIA cases to more fully understand how the HIA …

Acute Sterol O-Acyltransferase 2 (Soat2) Knockdown Rapidly Mobilizes Hepatic Cholesterol For Fecal Excretion, Stephanie M. Marshall, Anthony D Gromovsky, Kathryn L. Kelley, Matthew A. Davis, Martha D. Wilson, Richard G. Lee, Rosanne M. Crooke, Mark J. Graham, Lawrence L. Rudel, J. Mark Brown, Ryan E. Temel

Saha Cardiovascular Research Center Faculty Publications

The primary risk factor for atherosclerotic cardiovascular disease is LDL cholesterol, which can be reduced by increasing cholesterol excretion from the body. Fecal cholesterol excretion can be driven by a hepatobiliary as well as a non-biliary pathway known as transintestinal cholesterol efflux (TICE). We previously showed that chronic knockdown of the hepatic cholesterol esterifying enzyme sterol O-acyltransferase 2 (SOAT2) increased fecal cholesterol loss via TICE. To elucidate the initial events that stimulate TICE, C57Bl/6 mice were fed a high cholesterol diet to induce hepatic cholesterol accumulation and were then treated for 1 or 2 weeks with an antisense oligonucleotide targeting …

Advances In Neurovascular Treatments., Robert M Starke, Stephen J Monteith, Nohra Chalouhi, Dale Ding, Ricky Medel, David Hasan, Aaron S Dumont

Department of Neurosurgery Faculty Papers

No abstract provided.

Bedside Neurological Exams, Patrick Keane Bsn, Rn, Hannah Layfield Bsn, Rn

Patient Care Services / Nursing

No abstract provided.

Early Progressive Mobility- Letting Go Of Bedrest, Jacqueline Clapp Bsn, Rn, Holly Leighton Bsn, Rn, Kimberly Mclaughlin Bsn, Rn, Bridget Toy Bsn, Rn

Patient Care Services / Nursing

No abstract provided.

Pediatric Early Warning Score (Pews), Emily Keim Bsn, Rn, Jennifer Senske Bsn, Rn

Patient Care Services / Nursing

No abstract provided.

Teaching Patient To "Scip"---Skin Care Intervention Program, Kaitlyn Hoch Bsn, Rn, Kelsey Miller Bsn, Rn, Mary O'Connor Bsn, Rn, Nadiya Tverdun Bsn, Rn

Patient Care Services / Nursing

No abstract provided.

Falls In The Emergency Department (Adult), Katherine Andia Bsn, Rn, Emily Joyce

Patient Care Services / Nursing

No abstract provided.

Bedside Shift Handoff, Amelia Bard Bsn, Rn, Tyler Mclean Bsn, Rn, Mollie Rohrbach Bsn, Rn

Patient Care Services / Nursing

No abstract provided.

Point Of Care Testing On Adult Patients With Insulin And Vasopressor, Rachel Marouchoc Bsn, Rn, Rhyan Rupp Bsn, Rn

Patient Care Services / Nursing

No abstract provided.

Benefits Of Skin - To- Skin During Transition To Extrauterine Life, Michelle Martin Bsn, Rn, Corrine Rikli Bsn, Rn, Heather Witmer Bsn, Rn

Patient Care Services / Nursing

No abstract provided.

Newborn Cord Care Is Clean Cord Care As Effective As Antiseptic Agents In Preventing Infection And Decreasing Cord Separation Time?, Jaclynn Carl Bsn, Rn, Amy Hess Bsn, Rn, Felicia Mazzoni Bsn, Rn

Patient Care Services / Nursing

No abstract provided.

To Filter Or Not To Filter? (Poster), Julia Becker Bsn, Rn, Rachel Moser Bsn, Rn

Patient Care Services / Nursing

No abstract provided.

Reducing Wasted Supplies, Valerie Nederostek Bsn, Rn

Patient Care Services / Nursing

No abstract provided.

Pediatric Falls In The Outpatient Setting, Nicole Pasquarello Bsn, Rn

Patient Care Services / Nursing

No abstract provided.

Implementing A Nurse Shadowing Program For Medical Residents, Maria Fiore Bsn,Rn, Tara Getz Bsn, Rn, Melissa Lunney Bsn, Rn, Audrey Machose Bsn, Rn, Nina Patel Bsn, Rn

Patient Care Services / Nursing

No abstract provided.

Timing Of Insulin Administration, Zeena Bacchus Bsn, Rn

Patient Care Services / Nursing

No abstract provided.

Libraries Respond To Mobile Ubiquity: Research And Assessment Of Mobile Device Usage Trends For Academic And Medical Libraries, Megan M. Hurst, Eleanor I. Cook, J. Michael Lindsay, Martha F. Earl

Charleston Library Conference

The authors consider trends in mobile device usage for the Internet as a whole, for EBSCO Discovery Service across all client libraries, and at two specific libraries: Preston Medical Library, serving the University of Tennessee (UT) Graduate School of Medicine and UT Medical Center, and the Joyner Library at East Carolina University, serving students and faculty on the main campus. Librarians at Preston Medical Library conducted a survey to determine which mobile devices, platforms, and apps were used by their patrons in 2012. East Carolina University piloted an iPad and e-reader lending program in 2010–2011. The results of each are …

Bladder Cancer Versus Hemorrhagic Cystitis: A Case Of Mistaken Identity In A 34-Year-Old Male Undergoing Therapy For Granulomatosis With Polyangiitis, Jonathan Amatruda, Kevin D. Dieckhaus, Poornima Hegde, John A. Taylor Iii

Articles - Patient Care

A 34-year-old male was referred for management of bladder cancer noted on workup for gross hematuria and new-onset irritative voiding symptoms. The patient's history was significant for recently diagnosed granulomatosis with polyangiitis for which he was undergoing treatment with oral cyclophosphamide and corticosteroids. Cystoscopy revealed lesions suspicious for malignancy, but the patient was diagnosed with hemorrhagic cystitis secondary to BK virus infection upon cytology review, and immunostaining confirmed a polyomavirus infection of the urothelium. The patient's symptoms resolved after a modification of his immunosuppressive regimen, and antiviral therapy was ultimately unnecessary. Though symptomatic BK virus infection of the genitourinary tract …

Genome-Wide Analysis Of Regulatory Proteases Sequences Identified Through Bioinformatics Data Mining In Taenia Solium, Hong-Bin Yan, Zhong-Zi Lou, Li Li, Paul J. Brindley, Yadong Zheng, Xuenong Luo, Junling Hou, Aijiang Guo, Wan-Zhong Jia, Xuepeng Cai

Microbiology, Immunology, and Tropical Medicine Faculty Publications

Background

Cysticercosis remains a major neglected tropical disease of humanity in many regions, especially in sub-Saharan Africa, Central America and elsewhere. Owing to the emerging drug resistance and the inability of current drugs to prevent re-infection, identification of novel vaccines and chemotherapeutic agents against Taenia solium and related helminth pathogens is a public health priority. The T. solium genome and the predicted proteome were reported recently, providing a wealth of information from which new interventional targets might be identified. In order to characterize and classify the entire repertoire of protease-encoding genes of T. solium, which act fundamental biological roles in …

Phonemic Restoration In Developmental Dyslexia, Stephanie N. Del Tufo, Emily B. Myers

Open Access Author Fund Awardees' Articles

The comprehension of fluent speech in one's native language requires that listeners integrate the detailed acoustic-phonetic information available in the sound signal with linguistic knowledge. This interplay is especially apparent in the phoneme restoration effect, a phenomenon in which a missing phoneme is “restored” via the influence of top-down information from the lexicon and through bottom-up acoustic processing. Developmental dyslexia is a disorder characterized by an inability to read at the level of one's peers without any clear failure due to environmental influences. In the current study we utilized the phonemic restoration illusion paradigm to examine individual differences in phonemic …

Toward A Biocommunicable Cartography Of Health Decision-Making In The Amazon Basin Of Ecuador, James Cartwright

Lawrence University Honors Projects

This paper comprises a critical, ethnographic study of health communication in a rural community of Amazonian Ecuador. By synthesizing approaches from anthropology, discourse studies, and public health, the study explores how conversations influence health decisions, how communities understand health systems, and how macrostructural discourse changes the political economy of healthcare in Ecuador. My work draws on the recent theoretical development of ‘biocommunicability’ in anthropology as well as earlier sociological research on knowledge construction. Most importantly, this paper offers a critique of current interventions by NGOs in the region.

Micrornas: The Short Link Between Cancer And Rt-Induced Dna Damage Response., Christopher M Wright, Tu Dan, Adam Dicker Md, Phd, Nicole L Simone

Department of Radiation Oncology Faculty Papers

No abstract provided.

Host Species Restriction Of Middle East Respiratory Syndrome Coronavirus Through Its Receptor, Dipeptidyl Peptidase 4, Neeltje Van Doremalen, Kerri L. Miazgowicz, Shauna Milne-Price, Trenton Bushmaker, Shelly Robertson, Dana Scott, Joerg Kinne, Jason S. Mclellan

Dartmouth Scholarship

Middle East respiratory syndrome coronavirus (MERS-CoV) emerged in 2012. Recently, the MERS-CoV receptor dipeptidyl peptidase 4 (DPP4) was identified and the specific interaction of the receptor-binding domain (RBD) of MERS-CoV spike protein and DPP4 was determined by crystallography. Animal studies identified rhesus macaques but not hamsters, ferrets, or mice to be susceptible for MERS-CoV. Here, we investigated the role of DPP4 in this observed species tropism. Cell lines of human and nonhuman primate origin were permissive of MERS-CoV, whereas hamster, ferret, or mouse cell lines were not, despite the presence of DPP4. Expression of human DPP4 in nonsusceptible BHK and …

Sphingosine-1-Phosphate Promotes The Differentiation Of Adipose-Derived Stem Cells Into Endothelial Nitric Oxide Synthase (Enos) Expressing Endothelial-Like Cells., Divya Arya, Shaohua Chang, Paul J Dimuzio, Jeffrey Carpenter, Thomas N Tulenko

Department of Surgery Faculty Papers

BACKGROUND: Adipose tissue provides a readily available source of autologous stem cells. Adipose-derived stem cells (ASCs) have been proposed as a source for endothelial cell substitutes for lining the luminal surface of tissue engineered bypass grafts. Endothelial nitric oxide synthase (eNOS) is a key protein in endothelial cell function. Currently, endothelial differentiation from ASCs is limited by poor eNOS expression. The goal of this study was to investigate the role of three molecules, sphingosine-1-phosphate (S1P), bradykinin, and prostaglandin-E1 (PGE1) in ASC endothelial differentiation. Endothelial differentiation markers (CD31, vWF and eNOS) were used to evaluate the level of ASCs differentiation capability. …

Trend Analysis And Modeling Of Health And Environmental Data: Joinpoint And Functional Approach, Ram C. Kafle

USF Tampa Graduate Theses and Dissertations

The present study is divided into two parts: the first is on developing the statistical analysis and modeling of mortality (or incidence) trends using Bayesian joinpoint regression and the second is on fitting differential equations from time series data to derive the rate of change of carbon dioxide in the atmosphere.

Joinpoint regression model identifies significant changes in the trends of the incidence, mortality, and survival of a specific disease in a given population. Bayesian approach of joinpoint regression is widely used in modeling statistical data to identify the points in the trend where the significant changes occur. The purpose …

The Reproductive Lives Of Chuukese Women: Transnationalism In Guam And Chuuk, Sarah Ann Smith

USF Tampa Graduate Theses and Dissertations

Chuuk, one state of the Federated States of Micronesia (FSM), experiences significant transnational migration to the United States (U.S.), particularly to the Territory of Guam. This migration is facilitated by the Compact of Free Association (COFA), an agreement with several Micronesian countries previously under U.S. administration that allows for free movement of their citizens into the U.S. Although part of Micronesia, Guam's colonized residents resist an identity connected to rest of Micronesia. With very poor health outcomes, the Chuukese represent a political and social body of bodies that bring sickness, babies and increased costs to the Guam government without adequate …