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2014

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Articles 1621 - 1650 of 9579

Full-Text Articles in Medicine and Health Sciences

Allied Health Student Clinical Placements In Residential Aged Care Facilities: Staff Opinions, Attitudes, And Support Needs, Catherine Johnston, Clint Newstead, Sarah Walmsley, Lesley Macdonald Oct 2014

Allied Health Student Clinical Placements In Residential Aged Care Facilities: Staff Opinions, Attitudes, And Support Needs, Catherine Johnston, Clint Newstead, Sarah Walmsley, Lesley Macdonald

Internet Journal of Allied Health Sciences and Practice

Purpose: As the population ages, the incidence and prevalence of chronic health issues requiring allied health management is increasing. Currently, there is an undersupply of appropriately skilled allied health professionals working in aged care. This has also been identified as a setting in which many beginning health practitioners are reluctant to seek employment. In order to address this workforce shortage, it is imperative that students are prepared for a possible future career within aged care facilities. Early clinical experience within this setting may increase student confidence, raise awareness of the need for services, and encourage students to consider working in …


Hiv Infection And Cardiovascular Disease In Women, Julie A. Womack, Chung-Chou H. Chang, Kaku A. So-Armah, Charles Alcorn, Jason V. Baker, Cynthia L. Gibert, +17 Additional Authors Oct 2014

Hiv Infection And Cardiovascular Disease In Women, Julie A. Womack, Chung-Chou H. Chang, Kaku A. So-Armah, Charles Alcorn, Jason V. Baker, Cynthia L. Gibert, +17 Additional Authors

Medicine Faculty Publications

Background HIV infection is associated with increased risk of cardiovascular disease (CVD) in men. Whether HIV is an independent risk factor for CVD in women has not yet been established.

Methods and Results We analyzed data from the Veterans Aging Cohort Study on 2187 women (32% HIV infected [HIV+]) who were free of CVD at baseline. Participants were followed from their first clinical encounter on or after April 01, 2003 until a CVD event, death, or the last follow‐up date (December 31, 2009). The primary outcome was CVD (acute myocardial infarction [AMI], unstable angina, ischemic stroke, and heart …


Risk Assessment For Healthcare Workers After A Sentinel Case Of Rabies And Review Of The Literature, Virginia L. Kan, Patrick Joyce, Debra A. Benator, Kathleen Agnes, Janet Gill, Monica Irmler, Arlene Clark, George Giannakos, Audrey Gabourel, Fred M. Gordin Oct 2014

Risk Assessment For Healthcare Workers After A Sentinel Case Of Rabies And Review Of The Literature, Virginia L. Kan, Patrick Joyce, Debra A. Benator, Kathleen Agnes, Janet Gill, Monica Irmler, Arlene Clark, George Giannakos, Audrey Gabourel, Fred M. Gordin

Medicine Faculty Publications

Background. After a case of rabies, healthcare workers (HCWs) had fear of contagion from the infected patient. Although transmission of rabies to HCWs has never been documented, high-risk exposures theoretically include direct contact of broken skin and/or mucosa with saliva, tears, oropharyngeal secretions, cerebrospinal fluid, and neural tissue. Urine/kidney exposure posed a concern, as our patient's renal transplant was identified as the infection source.

Methods. Our risk assessment included (1) identification of exposed HCWs; (2) notification of HCWs; (3) risk assessment using a tool from the local health department; (4) supplemental screening for urine/kidney exposure; and (5) postexposure prophylaxis (PEP) …


Medicine + Health, Fall 2014, George Washington University, School Of Medicine And Health Sciences, Office Of Communications And Marketing Oct 2014

Medicine + Health, Fall 2014, George Washington University, School Of Medicine And Health Sciences, Office Of Communications And Marketing

Medicine + Health Magazine

No abstract provided.


Normative Scores For The Nih Toolbox Dynamic Visual Acuity Test From 3 To 85 Years, Carol Li, Jennifer L. Beaumont, Rose Marie Rine, Jerry Slotkin, Michael C. Schubert Oct 2014

Normative Scores For The Nih Toolbox Dynamic Visual Acuity Test From 3 To 85 Years, Carol Li, Jennifer L. Beaumont, Rose Marie Rine, Jerry Slotkin, Michael C. Schubert

Physical Therapy Faculty Research

As part of the National Institutes of HealthToolbox initiative, a computerized test of dynamic visual acuity (cDVA) was developed and validated as an easy-to-administer, cost- and timeefficient test of vestibular and visual function. To establish normative reference values, 3,992 individuals, aged 3–85 years, without vestibular pathology underwent cDVA testing at multiple clinical research testing facilities across the United States. Test scores were stratified by sociodemographic characteristics. cDVA was worse in males (p <0.001) and those subjects 50 years or older, while there was no difference in dynamic visual acuity across age groups binned from 3 to 49 years. Furthermore, we used these normative cDVA data as a criterion reference to compare both the long (validated) and short versions of the test. Both versions can distinguish between those with and without vestibular pathology (p D0.0002 long; p D0.0025 short). The intraclass correlation coefficient between longand short-cDVA tests was 0.86.


Raising Awareness For Interventions To Reduce Acute Care Transfers (Interact): Implementation Of “Stop And Watch” Tool, Gladys E. Sone-Ebeloue Oct 2014

Raising Awareness For Interventions To Reduce Acute Care Transfers (Interact): Implementation Of “Stop And Watch” Tool, Gladys E. Sone-Ebeloue

Doctor of Nursing Practice (DNP) Translational and Clinical Research Projects

Challenges in meeting the healthcare needs of the aging population have led to an increased rate of preventable hospitalizations, which are reported to be costly and detrimental to the health of the elderly, especially for those in Skilled Nursing Facilities (SNFs). Quality improvement initiatives have been proposed as an intervention to improve quality of care of individuals and populations. The purpose of this project was to raise awareness and set the foundation for staff engagement and empowerment in the use of INTERACT (Interventions to Reduce Acute Care Transfers) tools in a SNF. INTERACT is designed to improve quality of care …


Comparing The Effectiveness Of Small-Particle Versus Large-Particle Inhaled Corticosteroid In Copd, Dirkje S. Postma, Nicolas Roche, Gene L. Colice, Elliot Israel, Richard J. Martin, Willem Van Aalderen, Jonathan Grigg, Anne Burden, Elizabeth V. Hillyer, Julie Von Ziegenweidt, Gokul Gopalan, David Price Oct 2014

Comparing The Effectiveness Of Small-Particle Versus Large-Particle Inhaled Corticosteroid In Copd, Dirkje S. Postma, Nicolas Roche, Gene L. Colice, Elliot Israel, Richard J. Martin, Willem Van Aalderen, Jonathan Grigg, Anne Burden, Elizabeth V. Hillyer, Julie Von Ziegenweidt, Gokul Gopalan, David Price

Medicine Faculty Publications

Purpose: Small airway changes and dysfunction contribute importantly to airway obstruction in chronic obstructive pulmonary disease (COPD), which is currently treated with inhaled corticosteroids (ICS) and long-acting bronchodilators at Global initiative for Obstructive Lung Disease (GOLD) grades 2–4. This retrospective matched cohort analysis compared effectiveness of a representative small-particle ICS (extrafine beclomethasone) and larger-particle ICS (fluticasone) in primary care patients with COPD.


Patients and methods: Smokers and ex-smokers with COPD ≥40 years old initiating or stepping-up their dose of extrafine beclomethasone or fluticasone were matched 1:1 for demographic characteristics, index prescription year, concomitant therapies, and disease severity during 1 baseline …


Neonatal Nmda Receptor Blockade Disrupts Spike Timing And Glutamatergic Synapses In Fast Spiking Interneurons In A Nmda Receptor Hypofunction Model Of Schizophrenia, Kevin S. Jones, Joshua G. Corbin, Molly M. Huntsman Oct 2014

Neonatal Nmda Receptor Blockade Disrupts Spike Timing And Glutamatergic Synapses In Fast Spiking Interneurons In A Nmda Receptor Hypofunction Model Of Schizophrenia, Kevin S. Jones, Joshua G. Corbin, Molly M. Huntsman

Pediatrics Faculty Publications

The dysfunction of parvalbumin-positive, fast-spiking interneurons (FSI) is considered a primary contributor to the pathophysiology of schizophrenia (SZ), but deficits in FSI physiology have not been explicitly characterized. We show for the first time, that a widely-employed model of schizophrenia minimizes first spike latency and increases GluN2B-mediated current in neocortical FSIs. The reduction in FSI first-spike latency coincides with reduced expression of the Kv1.1 potassium channel subunit which provides a biophysical explanation for the abnormal spiking behavior. Similarly, the increase in NMDA current coincides with enhanced expression of the GluN2B NMDA receptor subunit, specifically in FSIs. In this study mice …


Preventing Slips And Falls Through Leisure-Time Physical Activity: Findings From A Study Of Limited-Service Restaurants, Alberto J. Caban-Martinez, Theodore K. Courtney, Wen-Ruey Chang, David A. Lombardi, Yueng-Hsiang Huang, Melanie J. Brennan, Melissa J. Perry, Jeffrey N. Katz, Santosh K. Verma Oct 2014

Preventing Slips And Falls Through Leisure-Time Physical Activity: Findings From A Study Of Limited-Service Restaurants, Alberto J. Caban-Martinez, Theodore K. Courtney, Wen-Ruey Chang, David A. Lombardi, Yueng-Hsiang Huang, Melanie J. Brennan, Melissa J. Perry, Jeffrey N. Katz, Santosh K. Verma

Environmental and Occupational Health Faculty Publications

Background/Objective

Physical activity has been shown to be beneficial at improving health in some medical conditions and in preventing injury. Epidemiologic studies suggest that physical activity is one factor associated with a decreased risk for slips and falls in the older (≥65 years) adult population. While the risk of slips and falls is generally lower in younger than in older adults; little is known of the relative contribution of physical activity in preventing slips and falls in younger adults. We examined whether engagement in leisure-time physical activity (LTPA) was protective of slips and falls among a younger/middle-aged (≤50 years old) …


Access To Comprehensive Perinatal Services Among Pregnant Women Enrolled In Both Medi-Cal And Covered California: Aligning And Integrating Care, Sara J. Rosenbaum, Carla Hurt, Mark Dorley, Sara Rothenberg, Nancy Lopez Oct 2014

Access To Comprehensive Perinatal Services Among Pregnant Women Enrolled In Both Medi-Cal And Covered California: Aligning And Integrating Care, Sara J. Rosenbaum, Carla Hurt, Mark Dorley, Sara Rothenberg, Nancy Lopez

Health Policy and Management Faculty Publications

Medi-Cal-enrolled women who are pregnant are entitled to coverage for enriched pregnancy-related care under Medi-Cal’s Comprehensive Perinatal Services Program (CPSP), a national landmark in the care and management of pregnant women with elevated health risks due to their low economic status. This entitlement applies to all pregnant women enrolled in Medi-Cal, including women who also are enrolled in subsidized health plans purchased through Covered California. The task that jointly faces Medi-Cal and Covered California is how best to align these two sources of pregnancy care financing in order to achieve a central goal of SB 857 – ensuring that dually …


Risk Attitudes And Characteristics Of Student Pharmacists Across Cohorts, Kristin Rose Villa Oct 2014

Risk Attitudes And Characteristics Of Student Pharmacists Across Cohorts, Kristin Rose Villa

Open Access Theses

In unstable environments, adaptation is a prerequisite for survival of organizations or groups. The Affordable Care Act has created a changing environment for health care providers. Unfortunately for Pharmacy, innovation within our profession has languished, leaving pharmacists in a precarious position. Many have noted the stagnation of the profession; in fact it has been a recurring theme in the commentary over the last five decades. The dialogue has focused on the externalities that represent barriers to the profession's evolution, including the direction change should take and the legal or organizational issues that inhibit change and innovation. Little attention has been …


Effects Of 5-Aza-2' Deoxycitidine And Sulforaphane On Major Histocompatibility Complex (Mhc) Classes I And Ii Surface Expression In Human Acute T-Cell Leukemia Cell Jurkat, Ali Salam Abdullah Ms Oct 2014

Effects Of 5-Aza-2' Deoxycitidine And Sulforaphane On Major Histocompatibility Complex (Mhc) Classes I And Ii Surface Expression In Human Acute T-Cell Leukemia Cell Jurkat, Ali Salam Abdullah Ms

All Student Scholarship

The immune system cells recognize and kill cancer cells by engaging the tumor antigens on the surfaces of cancer cells presented by the Major Histocompatibility Complex (MHC). Cancer cells can escape from immune system cells recognition and/or killing by down-regulating the MHC expression through genetic or epigenetic mechanisms.


Consumer-Oriented Drug Information Service Needs Assessment, Timothy K. Cheum, Kejal V. Patle, Rodney Richmond Oct 2014

Consumer-Oriented Drug Information Service Needs Assessment, Timothy K. Cheum, Kejal V. Patle, Rodney Richmond

Faculty Research ​and Publications

Federal legislation that has been introduced to amend the Social Security Act in order to provide for coverage of cognitive pharmacist services under the Medicare program in medically underserved communities. In the rural state of Arkansas this legislation would be well-received because a large portion of the state meets the criteria of a health professional shortage area. Considering the growing interest of using telecommunications as an alternative means of delivering healthcare services to medically underserved rural areas, a pharmacist-staffed consumer-oriented drug information service was explored. Over a 5-day period, 473 face-to-face consumer surveys were conducted in pharmacy and non-pharmacy settings …


Jefferson Digital Commons Quarterly Report: July-September 2014, Daniel G. Kipnis, Msi, Kelsey Duinkerken, Msi Oct 2014

Jefferson Digital Commons Quarterly Report: July-September 2014, Daniel G. Kipnis, Msi, Kelsey Duinkerken, Msi

Jefferson Digital Commons Reports

This Jefferson Digital Commons quarterly report will cover the following:

  • Milestone: 2 million downloads for the Jefferson Digital Commons
  • Some statistics
  • New assets added to the JDC
  • Historical Materials
  • What people are saying about the JDC


A Review Related To Midwifery Led Model Of Care, Shahnaz Shahid, Rafat Jan, Rahat Najam Qureshi, Salma Rattani Oct 2014

A Review Related To Midwifery Led Model Of Care, Shahnaz Shahid, Rafat Jan, Rahat Najam Qureshi, Salma Rattani

School of Nursing & Midwifery

Background: Midwifery led care (MLC) is a model of care in which perinatal care is provided to women throughout different phases of childbirth by a midwife.
Objective: This paper aims to provide a literature review on MLC.
Methods: A variety of databases and reports were considered to do the literature review on MLC. The search was limited from 1991 to 2011 by using keywords. A total of 50 articles were critically appraised for this review.
Findings: The main theme that emerged was women ’s satisfaction with MLC. Satisfaction was integrated with midwife ’s presence throughout childbirth, experience to …


Effect Of Age On Uterine And Ovarian Morphology With Polycystic Ovaries, Ambreen Usmani, Rehana Rehman, Aisha Qamar Oct 2014

Effect Of Age On Uterine And Ovarian Morphology With Polycystic Ovaries, Ambreen Usmani, Rehana Rehman, Aisha Qamar

Department of Biological & Biomedical Sciences

Abstract

Objective: To measure the outcome of age on ovarian and uterine morphology in primary infertile women with

polycystic ovaries.

Methods: The observational cross-sectional study was conducted from January 2009 to March 2010, and the

subjects were recruited from Ziauddin Hospital, Nazimabad, Karachi. The primary infertile subjects with polycystic

ovaries were subdivided into two age groups:20-30 years (group I), and 31-40 years (group II). Both groups had equal

number of subjects. The ovarian volume, follicles count and size, uterine area and endometrial thickness were

determined by transabdominal and transvaginal scans. Shapiro-Wilk's test and Mann-Whitney test were applied,

with p<0.05 being significant.

Results: …


Gsbs News, Fall 2014, Graduate School Of Biomedical Sciences, University Of Texas Health Science Center At Houston/M.D. Anderson Cancer Center Oct 2014

Gsbs News, Fall 2014, Graduate School Of Biomedical Sciences, University Of Texas Health Science Center At Houston/M.D. Anderson Cancer Center

GSBS News

No abstract provided.


Chess Improves Cancer Caregivers' Burden And Mood: Results Of An Ehealth Rct, Lori L. Dubenske, David H. Gustafson, Kang Namkoong, Robert P. Hawkins, Amy K. Atwood, Roger L. Brown, Ming-Yuan Chih, Fiona Mctavish, Cindy L. Carmack, Mary K. Buss, Ramaswamy Govindan, James F. Cleary Oct 2014

Chess Improves Cancer Caregivers' Burden And Mood: Results Of An Ehealth Rct, Lori L. Dubenske, David H. Gustafson, Kang Namkoong, Robert P. Hawkins, Amy K. Atwood, Roger L. Brown, Ming-Yuan Chih, Fiona Mctavish, Cindy L. Carmack, Mary K. Buss, Ramaswamy Govindan, James F. Cleary

Community & Leadership Development Faculty Publications

OBJECTIVE: Informal caregivers (family and friends) of people with cancer are often unprepared for their caregiving role, leading to increased burden or distress. Comprehensive Health Enhancement Support System (CHESS) is a Web-based lung cancer information, communication, and coaching system for caregivers. This randomized trial reports the impact on caregiver burden, disruptiveness, and mood of providing caregivers access to CHESS versus the Internet with a list of recommended lung cancer websites.

METHODS: A total of 285 informal caregivers of patients with advanced nonsmall cell lung cancer were randomly assigned to a comparison group that received Internet or a treatment group that …


Nanotechnology And Additive Manufacturing Platforms For Clinical Medicine: An Investigation Of 3d Printing Bioactive Constructs And Halloysite Nanotubes For Drug Delivery And Biomaterials, Jeffery A. Weisman Oct 2014

Nanotechnology And Additive Manufacturing Platforms For Clinical Medicine: An Investigation Of 3d Printing Bioactive Constructs And Halloysite Nanotubes For Drug Delivery And Biomaterials, Jeffery A. Weisman

Doctoral Dissertations

Personalized medicine requires the development of new technologies for controlled or targeted drug delivery. Three-dimensional (3D) printing and additive manufacturing techniques can be used to generate customized constructs for bioactive compound delivery. Nanotechnology in the form of nanoparticles, used as a stand-alone construct or for material enhancements, can significantly improve established biomaterials such as PMMA based bone cements or enable new technology to have enhanced capabilities. Combinations of the technologies can be used in such applications as infectious disease treatments, chemotherapeutic targeted drug delivery or targeted delivery of nearly any bioactive compound.

Chemotherapeutic or antibiotic enhanced 3D printing filaments were …


The Role Of Melanocortin 1 Receptor In Cutaneous Malignant Melanoma, Mary B. Steck Oct 2014

The Role Of Melanocortin 1 Receptor In Cutaneous Malignant Melanoma, Mary B. Steck

Publications

Cutaneous malignant melanoma (CMM) is an epidemic cancer in the United States. Survival rates for invasive CMM have not increased in past decades despite numerous clinical trials and the effective use of various combinations of chemotherapy agents to treat other cancers. Recent research has investigated the role of melanocortin 1 receptor (MC1R), a gene associated with red-hair phenotype in White individuals and with increased risk for developing CMM, in the mitogen-activated protein kinase (MAPK) pathway. This limited narrative review discusses the incidence, history, and risk factors for CMM. It explores familial CMM and provides a brief review of melanocyte development …


Medical Education Practice-Based Research Networks: Facilitating Collaborative Research, Alan Schwartz, Robin Young, Patricia J. Hicks, Ann Burke, Hilary M. Haftel, R. Mcgregor, L. Degnon, Carol Carraccio Oct 2014

Medical Education Practice-Based Research Networks: Facilitating Collaborative Research, Alan Schwartz, Robin Young, Patricia J. Hicks, Ann Burke, Hilary M. Haftel, R. Mcgregor, L. Degnon, Carol Carraccio

Pediatrics Faculty Publications

Background: Research networks formalize and institutionalize multi-site collaborations by establishing an infrastructure that enables network members to participate in research, propose new studies, and exploit study data to move the field forward. Although practice-based clinical research networks are now widespread, medical education research networks are rapidly emerging.Aims: In this article, we offer a definition of the medical education practice-based research network, a brief description of networks in existence in July 2014 and their features, and a more detailed case study of the emergence and early growth of one such network, the Association of Pediatric Program Directors Longitudinal Educational Assessment Research …


Antecedents Of Regular Exercise Among Women Who Do And Do Not Achieve Weight Loss Over Six Months, Heather Vartanian Oct 2014

Antecedents Of Regular Exercise Among Women Who Do And Do Not Achieve Weight Loss Over Six Months, Heather Vartanian

Dissertations (1934 -)

In the United States, 35.5% of adult women are classified as obese, defined as a body mass index (BMI) of > 30 kg/m2. The health risks associated with obesity can be mitigated through losing even 5-10% of initial body weight. Evidence shows that reductions in caloric intake alone without increases in caloric expenditure leads to a decline in resting metabolic rate, thereby impeding attainment or maintenance of weight loss. The purpose of this cross-sectional, mixed-methods study was to explore the antecedents of regular exercise among women with obesity who did and did not achieve weight loss over six months. The antecedents …


Hss Alumni News Fall 2014, Department Of Health And Sport Sciences Oct 2014

Hss Alumni News Fall 2014, Department Of Health And Sport Sciences

Health and Sport Sciences Newsletter

  • Becoming A Leader by Rachel Puthoff
  • Rike Dance/Fitness Room Remodel
  • Updates from the Majors
  • A Message from the Chair by Dr. Joan Rocks


Hss Departmental Developments Fall 2014, Department Of Health And Sport Sciences Oct 2014

Hss Departmental Developments Fall 2014, Department Of Health And Sport Sciences

Health and Sport Sciences Newsletter

  • Health Professions Club by Kailee Cialella
  • Rike 40th Anniversary Celebration
  • HSS Comprehensive Campaign Challenge
  • Updates from the Majors
  • The Strengths Perspective by Patti Wilson, MC
  • New Turf & Track
  • A Message from the Chair by Dr. Joan Rocks


Lymphedema: Pathophysiology, Diagnosis & Management, Bernadine Cruz Oct 2014

Lymphedema: Pathophysiology, Diagnosis & Management, Bernadine Cruz

Nursing Student Class Projects (Formerly MSN)

Lymphedema is a disfiguring condition whose hallmark is progressive, increasing swelling which occurs as a result of the accumulation of protein rich fluid in interstitial spaces. Those individuals who are affected suffer from either primary lymphedema or secondary lymphedema; the pathophysiology of both conditions is similar. Lymphedema can be a chronic, acute, or transient alteration, which can eventually lead to keratinization of the skin. An increase in the incidence of lymphedema has also been observed with increase in levels of obesity.


Atrial Fibrillation Post-Lung Lobectomy, Laura Adorni Oct 2014

Atrial Fibrillation Post-Lung Lobectomy, Laura Adorni

Nursing Student Class Projects (Formerly MSN)

According to the American Heart Association, atrial fibrillation affected 2.66 million individuals in the United States in 2010 and is expected to double by year 2050 (Sanoski, 2010, p. S11). Post-operative atrial fibrillation (POAF), a classification of atrial fibrillation (AF), can occur after thoracic surgery and is an ongoing source of morbidity and mortality (Imperatori et al., 2012). There is a 10-20% occurrence rate of POAF after non-cardiac surgery, such as a lung lobectomy, and a 40% incidence rate after a pneumonectomy (Omae & Kanmura, 2012, p. 429). Cardiovascular events such as heart failure, cerebral infarction, renal failure, and infection …


Myocardial Infarction (Mi) In Women, Samuel Agyenim Boateng Oct 2014

Myocardial Infarction (Mi) In Women, Samuel Agyenim Boateng

Nursing Student Class Projects (Formerly MSN)

Cardiovascular disease (CAD) is the most common cause of death for men and women in the US. The disease has been extensively studied in males (Gulati & Bairey Merz, 2012, p. 141). CVD poses an obvious challenge to the health of women. Coronary heart disease (CHD) is described as a "modern epidemic" (Banner, 2010, p. 3123). Although, the prevalence of CVD has prompted many studies for prevention and treatment, little is known about CVD in women. It Is now known that the mortality rates In women have surpassed that of men. Recent reports Indicate that CVD killed more women in …


Early Onset Alzheimer’S Disease In Individuals With Down Syndrome: Explored Theories Of Pathophysiology, Amanda Pack Oct 2014

Early Onset Alzheimer’S Disease In Individuals With Down Syndrome: Explored Theories Of Pathophysiology, Amanda Pack

Nursing Student Class Projects (Formerly MSN)

This presentation is a focus on some of the theories of the pathophysiology of early-onset Alzheimer’s Disease (AD) in individuals with Down Syndrome (DS). Down Syndrome, a genetic condition where an individual has a partial or full extra chromosome 21, is the most common chromosomal condition in the United States (National Down Syndrome Society (NDSS), 2012). Average life expectancy for individuals with DS has vastly increased in the last thirty years from age 25 to age 60 (NDSS, 2012). The extra chromosome genetically makes individuals with DS predisposed to certain conditions, including early onset dementia and AD, therefore as their …


Literary Research On Alport Syndrome, Shailendra Jain Oct 2014

Literary Research On Alport Syndrome, Shailendra Jain

Nursing Student Class Projects (Formerly MSN)

Alport syndrome is rare genetic disorder of the glomerulus in the kidneys that can be X-linked, Autosomal recessive, or Autosomal dominant in nature. Clinical manifestation includes hearing loss, hematuria, proteinuria, and hypertension (Cheungpasitporn, Kaewpoowat, Suksaranjit, Kittanamongkolchai, Srivali, Ungprasert, & Rangan, 2012). It is most common disease in males. A 24-hour urine specimen is usually obtained to check for proteinuria and elevated creatinine, which indicate acute renal failure (Cosgrove, 2012). A renal biopsy and ultrasounds is used to confirm the diagnosis of Alport Syndrome. Patients that are diagnosed with such disease require dialysis and referral to an ophthalmology and audiology. The …


Enterovirus D68, Kimberly Meyers Oct 2014

Enterovirus D68, Kimberly Meyers

Nursing Student Class Projects (Formerly MSN)

Enterovirus D68 (EVD68) “belongs to the family Picornaviridae, genus Enterovirus, and species Human enterovirus D: (Kaida et al.,2011, para.2). It is a small nonenveloped RNA virus (Xiang et al., 2012). EVD68 “shares characteristics with rhinoviruses, such as infection of the respiratory tract and acid lability” (Lauinger et al., 2012). There is no specific treatment for EVD68. Since the infection is caused by a virus, antibiotics would be ineffective. There are no antiviral medications currently available to treat EVD68 (Herold, 2014). Treatment may include antipyretics, cough medicines, bronchodilators, oxygen, and mechanical ventilation if required.