Medicine and Health Sciences Commons^™

Combining An Autologous Peripheral Nervous System “Bridge” And Matrix Modification By Chondroitinase Allows Robust, Functional Regeneration Beyond A Hemisection Lesion Of The Adult Rat Spinal Cord, John D. Houle, Veronica J. Tom, Debra A. Mayes, Gail Wagoner, Napoleon Phillips, Jerry Silver

Neuroscience, Cell Biology & Physiology Faculty Publications

Chondroitinase-ABC (ChABC) was applied to a cervical level 5 (C5) dorsal quadrant aspiration cavity of the adult rat spinal cord to degrade the local accumulation of inhibitory chondroitin sulfate proteoglycans. The intent was to enhance the extension of regenerated axons from the distal end of a peripheral nerve (PN) graft back into the C5 spinal cord, having bypassed a hemisection lesion at C3. ChABC-treated rats showed (1) gradual improvement in the range of forelimb swing during locomotion, with some animals progressing to the point of raising their forelimb above the nose, (2) an enhanced ability to use the forelimb in …

Psychometrically Equivalent Bisyllabic Words For Speech Reception Threshold Testing In Arabic, Elisha Rose Ratcliff

Theses and Dissertations

The use of speech audiometry is essential in audiological testing. One of the most important elements of speech audiometry is speech reception threshold. To provide services for the growing population of non-English speaking people, audiologists need speech audiometry materials in a variety of languages. The purpose of this study was to develop, digitally record, evaluate, and equate Arabic bisyllabic words for use in testing speech reception threshold. Ninety frequently used bisyllabic words were digitally recorded by a male talker of standard Arabic. These words were presented to 20 normally hearing subjects in 2 dB increments at intensity levels ranging from …

Long Acting, Reversible Veterinary Sedative And Analgesic And Method Of Use, Thomas Tobin

Veterinary Science Faculty Patents

A veterinary composition comprising a guanidine derivative, e.g., guanabenz or guanabenz acetate is provided which produces a rapid acting and long lasting sedative and analgesic effect in a subject animal that is selectively reversible. The use of guanabenz in the horse provides for a safe, effective, long lasting and rapidly reversible sedative and analgesic which can be used on the standing animal. Methods of use of the compositions of the invention are also provided.

Disease Risks Associated With Increasing Feral Swine Numbers And Distribution In The United States, Thomas Hutton, Thomas J. Deliberto, Sheldon Owen, Bruce Morrison

Michigan Bovine Tuberculosis Bibliography and Database

Feral hogs or “wild boars” come from several sources and include released or escaped domestic swine and the truly wild European boar. When free-roaming in North America, all are included in the term “feral swine,” as are hybrids of the two types. Although morphologically distinct, both the feral swine and European wild swine are recognized as Sus scrofa. The physical damage caused by feral swine has been well documented and includes damage to vehicles, vineyards, tree plantings, archaeological sites, agricultural crops, turf, soils, rare plant communities, and wildlife habitat (Seward et al. 2004). In addition they compete with livestock …

Ada News - 07/10/2006, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Psychometrically Equivalent Bisyllabic Word Lists For Word Recognition Testing In Taiwan Mandarin, Alycia Jane Dukes

Theses and Dissertations

The aim of this study was to develop, digitally record, evaluate, and psychometrically equate a set of Taiwan Mandarin bisyllabic word lists to be used for word recognition testing. Frequently used bisyllabic words were selected and digitally recorded by male and female talkers of Taiwan Mandarin. Twenty normally hearing subjects were presented each word to find the percentage of words which they could correctly recognize. Each word was measured at 10 intensity levels (-5 to 40 dB HL) in increments of 5 dB. Logistic regression was used to include 200 words with the steepest logistic regression slopes in four psychometrically …

Current Concepts In The Diagnosis And Treatment Of Typhoid Fever, Zulfiqar A. Bhutta

Department of Paediatrics and Child Health

No abstract provided.

Don't Bring Me Your Tired, Your Poor: The Crowded State Of America's Emergency Departments, Jessamyn Taylor

National Health Policy Forum

If the time comes, people expect that the emergency department (ED) will have the resources necessary to treat them in a timely, high-quality manner. Increasingly, however, EDs may not be able to meet that expectation. Hospitals in urban areas with large populations, high population growth, and higher-than-average numbers of uninsured are particularly crowded: ambulances are often diverted to other hospitals and patients are frequently forced to “board” in the hallways (while they wait to be transferred to another facility or part of the hospital). This issue brief places EDs in the context of the U.S. health care system and its …

Speech Reception Threshold Materials For Taiwan Mandarin, Katie Bedke Slade

Theses and Dissertations

Speech reception threshold (SRT) tools have been developed to assist in the evaluation of hearing. This study was performed to develop, digitally record, evaluate, and equate Taiwan Mandarin trisyllabic words which can be used to measure the SRT. Eighty-nine commonly used trisyllabic words were chosen and digitally recorded by native male and female speakers. The words were then presented to 20 normally hearing subjects at 14 intensity levels (-10 to 16 dB HL) with 2 dB increments. Psychometric function slopes were calculated using logistic regression. Twenty-eight words with steep psychometric function were selected and digitally adjusted to match the mean …

Aboriginal Health Workers And Diabetes Care In Remote Community Health Centres: A Mixed Method Analysis, Damin Si, Ross S. Bailie, Samantha J. Togni, Peter H N D'Abbs, Gary W. Robinson

Aboriginal Policy Research Consortium International (APRCi)

Objective: To assess the effect of employing Aboriginal health workers (AHWs) on delivery of diabetes care in remote community health centres, and to identify barriers related to AHWs’ involvement in diabetes and other chronic illness care.

Design, setting and participants: Three-year follow-up study of 137 Aboriginal people with type 2 diabetes in seven remote community health centres in the Northern Territory.

Main outcome measures: Delivery of guideline-scheduled diabetes services; intermediate outcomes (glycated haemoglobin [HbA1c] and blood pressure levels); number and sex of AHWs at health centres over time; barriers to AHWs’ involvement in chronic illness care.

Results: There was a …

Causal Comparisons In Randomized Trials Of Two Active Treatments: The Effect Of Supervised Exercise To Promote Smoking Cessation, Jason Roy, Joseph W. Hogan

COBRA Preprint Series

In behavioral medicine trials, such as smoking cessation trials, two or more active treatments are often compared. Noncompliance by some subjects with their assigned treatment poses a challenge to the data analyst. Causal parameters of interest might include those defined by subpopulations based on their potential compliance status under each assignment, using the principal stratification framework (e.g., causal effect of new therapy compared to standard therapy among subjects that would comply with either intervention). Even if subjects in one arm do not have access to the other treatment(s), the causal effect of each treatment typically can only be identified from …

The Effect Of Hus1 On Ionizing Radiation Sensitivity Is Associated With Homologous Recombination Repair But Is Independent Of Non-Homologous End-Joining, Robert S. Weiss, Xiang Wang, Baocheng Hu, Ya Wang

Department of Radiation Oncology Faculty Papers

Mammalian Hus1 plays an important role in maintaining genomic integrity. Cells lacking mouse Hus1 are hypersensitive to DNA damage inducers including UV and camptothecin (CPT). By using clonogenic assay, we show here that Hus1 deficient mouse cells are hypersensitive to ionizing radiation (IR) compared with their Hus1-positive counterparts. However, these cells show similar induction levels and similar rejoining rates of DNA double strand breaks (DSBs) following IR, indicating that the effect of Hus1 on cell radiosensitivity is independent of non-homologous end-joining (NHEJ). By combining an I-SceI-induced-DNA DSBs system and a siRNA approach, we also show that knocking down Hus1 decreases …

Healthnet News V.21:No.2 Summer 2006, Judith S. Kronick, Alberta Richetelle

Articles - Patient Care

A newsletter for public librarians and others interested in consumer health information services.

Epigenetic Alterations In Rassf1a In Human Aberrant Crypt Foci, Emily J. Greenspan, Melissa A. Jablonski, Thiruchandurai V. Rajan, Joel Levine, Glenn S. Belinsky, Daniel W. Rosenberg

UCHC Articles - Research

CpG island methylation (CIM) is an epigenetic mechanism for transcriptional silencing that occurs at various stages of colon tumorigenesis. CIM has been found in serrated adenomas and hyperplastic polyps. There is also evidence for hypermethylation in aberrant crypt foci (ACF) that are found in resected colons from cancer patients. Our study addresses promoter methylation of a tumor suppressor gene, RASSF1A, within the colonic epithelium of subjects undergoing screening colonoscopies in the absence of synchronous tumors. Patients included in this study were at elevated risk for colorectal cancer (CRC) based on family history, but without a previously occurring or synchronous …

Mid-Atlantic Ethics Committee Newsletter, Summer 2006

Mid-Atlantic Ethics Committee Newsletter

No abstract provided.

Santa Clara Magazine Volume 48 Number 1, Summer 2006, Santa Clara University

Santa Clara Magazine

8 - THE MAN BEHIND THE SOUND by Karen Crocker Snell. As a young music-loving soldier in the final days of World War II, John T. "Jack" Mullin '36 went to investigate a German recording device called a magnetophon. His resulting work in sound profoundly affected the field of recorded audio.

14 - THREE ROOMMATES IN PARIS By John Patrick Donnelly, S.J. It has been 500 years since Francisco Xavier and Pierre Favre were born, and 450 years since the death of Ignatius of Loyola. Quite a lot has happened since 1529 at the University of Paris, when the three …

Posttraumatic Stress Disorder And Civil War Reenactors, Kimberlee Bruce

Graduate Research Projects

The purpose of this phenomenological study was to explore the meaning of Civil War reenactments in military men with symptoms of posttraumatic stress disorder (PTSD). Six Caucasian males who have PTSD symptoms were interviewed in depth by responding to two questions. I. Why do you reenact? And 2. What sticks out in your mind about Civil War reenacting after having served in the military? Five themes emerged; escaping reality, structure and discipline, honor and duty, friendship and companionship, and love of history. The findings of this study will add to the body of nursing knowledge about PTSD by exploring a …

Correlation Between Impairment And Motor Performance During Reaching Tasks In Subjects With Spastic Hemiparesis, Charles Leonard, Kelsey A. Gardipee, Jennifer R. Koontz, John-Henry Anderson, Scott A. Wilkins

Physical Therapy and Rehabilitation Science Faculty Publications

Objective: The main purposes of this study were to examine, in subjects with chronic hemiparesis following a stroke: (i) the correlations between tests of muscle tone, stiffness, spasticity, paresis and co-contraction, and (ii) the correlations of these tests and measurements of impairment to upper extremity motor performance.

Design: Prospective, cross-sectional, correlation matrix using sample of convenience.

Subjects: Thirteen subjects with chronic hemiparesis secondary to a cerebrovascular accident (stroke) were tested.

Methods: Subjects were assessed using the Fugl-Meyer Upper Extremity Motor Assessment, modified Ashworth scale, deep tendon reflexes, and muscle characteristics that included quantification of muscle stiffness, paresis and co-contraction during …

Dentalgram - Vol. 20, No. 07, Loma Linda University School Of Dentistry

Dentalgram

In this issue:

• Dental anesthesiology to become independent surgery center
• Dental hygiene table clinic takes top prize
• News from computer services department
• Keeping Connected - 'Pets are people too'
• Class of 2008 - advanced education program in orthodontics and dentofacial orthopedics
• Blackboard tip for July
• Grantsmanship Training Program held June 12-16

Functional Family Therapy: An Interview With Dr. James Alexander, Dr. Jill D. Duba

Counseling & Student Affairs Faculty Publications

This article presents the functional family therapy of James Alexander, focusing on his work with high risk youth who are high risk, delinquent, and who abuse substances. The interview addresses evidence-based interventions, indivudalizing treatment, and prevention of violence. Training efforts and recent developments in functional family therapy are discussed.

Measuring The Influence Of Built Neighborhood Environments On Walking In Older Adults, Yvonne L. Michael, Tracey Beard, Dongseok Choi, Stephanie Farquhar, Nichole Carlson

Community Health Faculty Publications and Presentations

Examined the degree of association between perceived and objective characteristics of the neighborhood environment and the relation of each type of measurement to neighborhood walking in older adults. Participants included 105 adults aged 65-92 (mean age 75.1) from 10 neighborhoods in Portland, Oregon, participating in Senior Health and Physical Exercise (SHAPE), a randomized walking intervention. Neighborhoods were stratified by a "walking friendliness" ranking variable. This variable was derived for each neighborhood based on available social and environmental data that were hypothesized to correlate with walking and physical activity: high income, high older adult population density, high proportion of white residents, …

Altered Gene Expression Induced By Ionizing Radiation And Glycolytic Inhibitor 2-Deoxy-Glucose In A Human Glioma Cell Line: Implications For Radio Sensitization, Katherine Heminger, Viney Jain, Madhavi Kadakia, B. Dwarakanath, Steven J. Berberich

Educator Preparation & Leadership Faculty Works

The glycolytic inhibitor 2-deoxy-D-glucose (2DG) has been shown to enhance the cell death induced by radiation and other DNA damaging agents selectively in cells with high rates of glycolysis, like cancer cells. While energy linked modification of DNA and cellular repair processes have been suggested as possible mechanisms of sensitization, other effects such as global stress response cannot be excluded. In this pilot study, we have investigated the effect of 2-DG and radiation on the transcriptome in an attempt to elucidate how 2-DG impacts gene expression in undamaged verses irradiation (IR) damaged cells using a human malignant glioma cell line, …

The Current Level Of Nursing Knowledge Regarding The Management Of Cardiovascular Disease In Postmenopausal Women, Lynda Smith Hardin

MSN Research Projects

Cardiovascular disease (CYD) is the single leading cause o f death and a significant cause o f morbidity o f American women. Despite years of research and compelling data indicating that CYD is largely preventable, alarming trends in the prevalence and management o f risk factors in women continue to occur. In 2005, the estimated direct and indirect cost o f CYD was $393.5 billion (American Heart Association [AHA], 2005). Despite the fact that CYD kills more women per year than the next six causes of death combined; only 13% o f women consider CYD to be their greatest health …

The Relationship Between The Health Behaviors Of Female University Freshmen And Their Academic Success, Courtney Taylor

MSN Research Projects

The purpose o f this study was to characterize the relationship between the health behaviors and academic achievement o f university women. To this end, female freshmen at Mississippi University for Women were given questionnaires measuring their healthrelated lifestyle habits that were then correlated with the students’ grade point averages. Lifestyle habits were assessed via the Wellness Worksheet questionnaire (WW), and academic success, first semester grade point averages (GPA). The analysis revealed a moderately weak and positive relationship between healthier lifestyle choices and first semester GPA, r = .34. Among the behaviors addressed by the WW, alcohol and other drug …

Role Of The Nurse Practitioner: Health Promotion And Education In Teenage Pregnancy Prevention, Alissa Anne Hood

MSN Research Projects

According to Martin, Kochanek, Strobino, Guyer, & MacDorman (2005), the lowest reported rate in the past six decades for teenage pregnancy in the United States occurred in the year 2003. Although this was found significant, the United States still holds the highest rate of teenage pregnancy in the industrialized world. It has been estimated that by the year 2010 there will be a 10% increase in the number of teenage girls between the ages of 15-19(Coren, 2005). Therefore, it was found imperative to increase the awareness and promotion of healthy sexual behaviors to reduce further teenage pregnancy. The purpose of …

Patient Satisfaction With Nurse Practitioner Care In Telemergency, Melissa Henry King

MSN Research Projects

Recent studies suggest that patient satisfaction has a direct correlation to patient outcome. In today’s healthcare system, satisfaction is the ultimate measure of services rendered from a provider to a consumer. From retail sales to the delivery of healthcare services, satisfaction surveys are highly regarded by the provider of services as a means to correct and improve products or services. A patient who is not satisfied with provided services will seek out providers with whom they gain the greatest amount of satisfaction. Telemergency is a fairly new concept that is growing rapidly in popularity with both hospital administrations and providers. …

The Ethics Of Referral, Bernard Rollin

Professional Veterinary Ethics Collection

The rapid growth of veterinary specialty practices has created a number of vexatious ethical issues relevant to veterinary medicine. The preeminent question pertains to “the duty to refer.” Do primary care practitioners have such a moral duty? If so, when does this duty arise? Does it pertain in all cases where specialized knowledge is relevant to a disease?

This raises the fundamental question of “Veterinary Ethics” — namely, does the veterinarian ideally have primary obligation to the client/owner or the animal? (1) There are 2 possible ideal types that a veterinarian can aim for — the Garage Mechanic Model or …

Time Course Of Substance P Expression In Dorsal Root Ganglia Following Complete Spinal Nerve Transection, Wendy Weissner, Barbara J. Winterson, Alan Stuart-Tilley, Marshall Devor, Geoffrey M. Bove

Biomedical Sciences Faculty Publications

Recent evidence suggests that substance P (SP) is upregulated in primary sensory neurons following axotomy, and that this change occurs in larger neurons that do not usually produce SP. If so, this upregulation may allow normally neighboring, uninjured, and non-nociceptive dorsal root ganglion (DRG) neurons to become effective in activating pain pathways. Using immunohistochemistry, we performed a unilateral L5 spinal nerve transection upon male Wistar rats, and measured SP expression in ipsilateral L4 and L5 DRGs and contralateral L5 DRGs, at 1 to 14 days postoperatively (dpo), and in control and sham operated rats. In normal and sham operated DRGs, …

What's Happening: July, 2006, Maine Medical Center

What's Happening

No abstract provided.

Predictors Of Influenza Immunization Among Home Care Clients In Ontario, John P. Hirdes, Dawn M. Dalby, R. Knight Steel, G. Iain Carpenter, Roberto Bernabei, John N. Morris, Brant E. Fries

Kinesiology and Physical Education Faculty Publications

Background: This study examined factors associated with the receipt of influenza vaccination among Ontario home care clients.

Methods: Home care clients were assessed, as part of a routine home visit, during a pilot study of the Resident Assessment Instrument – Home Care (RAI-HC) in 12 Ontario Community Care Access Centres (CCACs). The RAI-HC is a multidimensional assessment that identifies clients’ needs and level of functional ability. Multiple logistic regression was used to identify factors associated with influenza immunization in the two years prior to assessment.

Results: The overall rate of immunization reached about 80% by 2002. Factors …