Medicine and Health Sciences Commons^™

Investigations Into Dna Vaccination Against Channel Catfish Virus, Heather C. Harbottle

LSU Doctoral Dissertations

The leading viral killer of commercially produced channel catfish is Channel Catfish Virus (CCV). Studies conducted to evaluate DNA vaccination against CCV compared encoded gene, dose, multiple DNA vaccines, and immune response to vaccination. Genes were selected (ORFs 1 and 3 [immediate early genes], ORFs 6, 19, and 46 [membrane genes], and ORF59 [putative major envelope glycoprotein gene], cloned into a plasmid, and expressed in mammalian and fish cell culture to detect predicted molecular weight proteins. Plasmid vaccines were injected into fish muscle in doses of 50 μg, 25 μg, 5 μg, or 1 μg and efficacy was evaluated upon …

The Effectiveness Of Language-Literacy Training For Child Care Workers, Katelyn Beth Venturella

LSU Master's Theses

The purpose of the current study was to examine the effectiveness of group-based language-literacy training for child care workers. The first phase of the study followed a pre-post single group comparison design and involved 23 child care providers. The independent variable was the teacher training and the dependant variable was scores from a questionnaire. The second phase of the study involved a sub-group of four child care workers who received one-on-one follow up training after the group sessions. The questionnaire was administered a third time to the follow-up group. An analysis of the questionnaire items at pretest indicated that the …

Developing Embryo Technologies For The Eland Antelope (Taurotragus Oryx), Gemechu G. Wirtu

LSU Doctoral Dissertations

Assisted reproductive technologies developed in domestic cattle serve as a starting point in similar studies on nondomestic bovids. The common eland is a useful model species for studies on rare tragelaphine antelopes. In Chapter 3 of the present study, effects of components/attributes of protein-free embryo culture media on the in vitro development of in vitro-derived bovine embryos were evaluated. A 2 x 2 factorial study comparing effects of groups of amino acids (20aa or 11aa) in two base media (modified KSOM or BM-3) demonstrated that amino acids and base medium affected embryonic development. A subsequent 7 x 2 factorial experiment …

Louisiana State University Nasalance Protocol Standardization, Kathryn Ruth Kendrick

LSU Master's Theses

It was the purpose of this study to obtain nasalance values using the Nasometer and a resonance evaluation created at the Louisiana State University (LSU) Speech and Hearing Clinic. The Nasometer was used to measure the amount of nasal acoustic energy in the speech of 40 normal young adults during sustained vowel production, consonant vowel reduplications, and connected speech using the Rainbow Passage. Means and standard deviations are presented for the individual speech tasks and according to gender. Nasalance values for the sustained vowels were significantly higher for the high front vowel /i/ than any other vowel, and the lowest …

Methods To Induce Earlier Onset Of Cyclicity In Transitional Mares, Abdulhakeem Hashim Aljarrah

LSU Master's Theses

The purpose of this study was to investigate methods to induce earlier onset of cyclicity in transitional mares. Two experiments were conducted evaluating the effect of follicular aspiration to advance the onset of cyclicity, more succinctly define criteria for selection of mares for follicular aspiration and to compare aspiration to deslorelin treatment for initiating cyclicity in transitional mares. In Experiment 1, anestrous mares were assigned to control (n=6) or follicular aspiration (n=11). The control mares were monitored twice weekly, until ovulation was detected. The aspiration mares were similarly monitored until a follicle >35 mm was identified, then transvaginal ultrasound guided …

In Vitro Evaluation Of The Securos Cranial Cruciate Ligament Repair System And Fluorocarbon Leader Line For Use As Lateral Fabella-Tibial Sutures, Max Nielsen Banwell

LSU Master's Theses

Cranial cruciate ligament (CCL) rupture is a common injury in the dog and major cause of degenerative joint disease. The pathophysiology of CCL rupture in the dog is well described. Osteoarthritis secondary to CCL rupture causes severe pain and lameness. There are many surgical techniques accepted for dogs with CCL rupture. A commonly performed technique is an extracapsular repair with a lateral fabella-tibial suture (LFS) using large diameter nylon leader line (NLL). Mechanical demands placed upon the LFS are high requiring the material used be able to withstand a high amount of force, undergo minimal elongation, and have a high …

Evaluation Of Rough Brucella Strains As Vaccines For Brucellosis And Pseudorabies In Swine, Lorraine Harrow Molin

LSU Master's Theses

Brucellosis and pseudorabies lead to abortion in pregnant sows and are perpetuated by feral swine reservoirs. A multivalent oral vaccine for these diseases would improve vaccination and eradication programs worldwide. Previous studies have shown that the rough attenuated Brucella strains RB51 and VTRS1, when administered subcutaneously to swine, stimulate host immune responses, transiently colonize tissues, and provide partial protection against virulent B. suis infection in pregnant sows. A plasmid encoding for the pseudorabies virus glycoprotein D (PRV gD) has also been added to these strains as part of this project. This study evaluates the use of these strains as oral …

A Lived Experience Of Being A Mother Of A Child With Depression: A Hermeneutic Phenomenological Inquiry, Maralou R. Brose

Theses and Graduate Projects

There have been few studies that have attempted to understand the world of parents raising a child with depression. This study introduces the magnitude of the problem of childhood depression and explores what it means to be the mother of an adolescent with depression. For this study, three mothers of adolescents wit.h depression were questioned interviews were in unstructured interviews. The taped transcribed, and the resulting texts were Four core themes were analyzed using a six-stage process. extracted-maternal role, support, and grief-and reveal_ed what it was family disequilibrium, like for mothers raising a child with depression. Hermeneutic phenomenology provided the …

The Role Of Erp57 In Hras Intracellular Trafficking And Function., Jaime Lyn Parman

Electronic Theses and Dissertations

Ras is a central player in signal transduction that mediates cellular proliferation and differentiation. Recent evidence has shown that lipid and non-lipid modified domains participate in Ras traffic and that plasma membrane association is mediated by vectorial vesicular transport from the endomembrane system. ERp57, an ER chaperone, has been shown to specifically bind farnesylated Hras but not non-farnesylated Hras. The objective of this study was to determine if ERp57 participates in Ras trafficking and function. First, the effect of ERp57 knock down by siRNA technology on Hras function was studied; there was a reduction in ERp57 cellular levels that led …

Flavone: The Molecular And Mechanistic Study Of How A Simple Flavonoid Protects Dna From Oxidative Damage., Jennifer Dawn Dean

Electronic Theses and Dissertations

Dietary flavonoids are ubiquitous and are marketed as supplements. Characterized as antioxidants, they offer protection against a number of degenerative diseases. Flavonoid mechanics involve free radical scavenging, metal chelation, and substrate association. The skeletal structure of flavonoids is a fused ring system modified by hydroxyl, sugar, and carbohydrate additions. Flavone is a structurally simple flavonoid. Quercetin and its glycosidic analog rutin are complex structures. Using a DNA oxidation/cleavage assay, flavone reduces DNA nicking by 91%. Depending on the solvent system used, quercetin can either increase or decrease DNA oxidation. Rutin exhibits neither pro- nor antioxidant activity. The molecular interactions responsible …

Barriers To Domestic Violence Screening In The Emergency Department, Lisa Yonaka

Master's Projects

Are you in a relationship in which you're being abused? That is not an easy question to answer or ask. Identification of those who are victims of domestic violence is important to prevent further abuse and injury. The purpose of this non-experimental study was to determine barriers of Emergency Department Registered Nurses screening patients for domestic violence. 33 ED RNs completed a short anonymous questionnaire that was developed by Dr. Mary Lou Moore, Wake Forrest University, Winston-Salem, North Carolina. The most significant barriers to screening identified, were the lack of education on how to ask questions about abuse, language barriers, …

The Relationship Of Health Beliefs And Health Value In Cardiovascular Outcomes, Kimberley Schaub

All-Inclusive List of Electronic Theses and Dissertations

Despite extensive theoretical information regarding Schwarzer's Health Action Process Approach the utility of the model pas yet to be explored within a chronic illness population. Using Schwarzer's Health Action Process Approach (Schwarzer, 1992), the purpose of this study was to investigate cardiovascular outcomes based on health beliefs and health value. Participants were eighty-one adults ages 42-87 with cardiovascular disease recruited from a cardiac rehabilitation program in Central Indiana. Participants completed instruments that assessed (a) health beliefs, (b) health value and, (c), quality of life. Measurements of physiological outcome (resting heart rate, distance walked, and metabolic equivalent) were also obtained. A …

Sensory Evaluation Of Gluten-Free Brownies Prepared Using Green Banana Flour, Banana-Potato Blend And Rice-Potato-Tapioca Blend, Sonia F. Murgueytio

All-Inclusive List of Electronic Theses and Dissertations

Increasing numbers of people worldwide are being diagnosed with Celiac Disease, an intestinal disorder caused by ingestion of foods containing gluten. Traditional baked goods are prepared using wheat flour that contains gluten. Literature suggests that the absorptive surface of the small intestine is damaged in people susceptible to gluten. Alternative gluten-free products are needed to improve the health of people with this disease. The purpose of this study was to assess the overall acceptability and palatability of chocolate brownies made with 100% banana flour or a blend of banana flour and potato starch. Appearance, color, texture, flavor and overall acceptability …

Occupational Therapy Job Satisfaction In The Geriatric Setting, Dawn Doctor

Masters Theses

This study examined the level of job satisfaction among occupational therapists working in the geriatric setting in the state of Michigan. The purpose of this study was to determine if burnout exists among occupational therapists working in a geriatric setting. Questionnaires from 29 therapists who work in a·geriatric setting were analyzed. The majority of the respondents reveled they are not burned out, but do report at least one sign of stress within their job. The most common forms of stress were treating difficult diagnoses, excessive paperwork, excessive caseload, increased productivity expectations, the lack of respect for occupational therapy, and the …

The Relationship Between Childbirth Experience And Psychological Functioning In The Postpartum Period, Dena Dian Daniel

Graduate Theses

The purpose of this research is to examine the relationships between the mother's perception of the birth experience, symptoms of the post-traumatic stress, and symptoms of postpartum depression. Sixty-seven participants ranging from 17 to 40 years of age completed a self-report questionnaire containing items from three instruments including the Perception of Birth Scale, the Edinburgh Postnatal Depression Scale, and the Davidson Trauma Scale. The findings reveal a more negative perception of the birth experience is significantly related to a greater frequency and/or. severity of. post- traumatic stress and postpartum depression symptoms following childbirth., These findings support the conclusion that an …

Does Exercise And Placement Technique Affect Triceps Surae Thermocouple Position As Measured By Magnetic Resonance Imaging?, Breanne A. Piatt

All-Inclusive List of Electronic Theses and Dissertations

Context: Intramuscular temperatures are commonly recorded with the use of implantable thermocouples. Currently, there are 2 techniques of inserting intramuscular thermocouples, a traditional technique, which inserts the thermocouple with a sterile hypodermic needle, then retracts the needle, and a catheter-assisted technique, which uses a spring-loaded catheter to insert the catheter then a thermocouple is fed through the catheter to target position. Objective: The purpose of this study was first to investigate whether or not target position is obtained with either insertion method. A second purpose of this study was to quantify the amount of movement that occurs after exercise. Lastly, …

Clinical Effectiveness Of A Subperiosteal Anchorage Device, Monica Anne Witte

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this pilot study was to evaluate the clinical efficacy of a subperiosteal anchorage device, the palatal OnPlant™, during orthodontic retraction of protruding anterior teeth in cases requiring maxillary premolar extraction. Seven subjects (5 female, 2 male), ages 13 to 55, were selected for the study. The OnPlant was surgically placed in the mid-palatal region through a well-defined subperiosteal tunnel. Following the manufacturer recommended osseointegration period of four months, the OnPlant was uncovered and attached to the first molars by means of a transpalatal bar. Standard orthodontic treatment then commenced to retract the anterior teeth after the first …

Measured Effects Of Rapid Palatal Expansion On Nasal Cavity Volume Utilizing Cbct, Jon Neal Robinson

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was to evaluate and predict the expected changes that occur in the nasal cavity volume following rapid palatal expansion. Eighteen subjects (11 female, 7 male), ages 9 to 18, requiring rapid palatal expansion in conjunction with comprehensive orthodontic treatment, were selected for the study. Rapid palatal expansion was accomplished using the standard, banded hyrax appliance. Three-dimensional cone beam computed tomograms using the NewTom 9000™ were acquired before and after expansion. Serial coronal slices of the nasal cavity were made using the QV9000™ software program. The resultant serial images were imported into 3-D Doctor™ for analysis …

Comparison Of Bracket Bond Strength By Total, Self-Etch And Laser Treatment, Kyo Sung Shawn Kim

Loma Linda University Electronic Theses, Dissertations & Projects

Laser etching of enamel surfaces alters the physical and chemical characteristics of the enamel. These changes in characteristics enhance the bonding to enamel. The purpose of this study was to compare the shear and tensile bond strength of Er,Cr:YSGG hydrokinetic laser system (Biolase) with 37% phosphoric acid and self etching primer 30 minutes and 72 hours after bonding. Four different laser power output setting was observed: 1.5W, 2.0W, 2.5W, and 3.0W. Two hundred forty bovine teeth free of defect, caries, and dentin exposure were mounted in acrylic resin and divided into 24 groups of 10 teeth. Sixteen groups of 10 …

A Bond Strength Comparison Of Led And Halogen Light Curing Units, John Richard Kavanagh

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this research was to compare the tensile bond strength of orthodontic flat based buttons bonded to bovine teeth with four commercial light-emitting diode (LED) curing lights and one conventional quartz tungsten halogen (QTH) curing light.

The dental market has recently been introduced to a number of commercially available light-emitting diode (LED) curing lights. Tensile bond strength was evaluated for LED curing lights (Rembrandt® Allegro^TM, Den-Mat Corp, Santa Maria, CA), (LEDemetron, Kerr/Demetron Corp, Danbury, Conn), (Ortholux LED, 3M^TMESPE^TM, St. Paul, MN),and (FLASH-lite 1001, Discus Dental, Culver City, CA) are compared with one …

The Histological Effects Of Mandibular Distraction Osteogenesis On Rabbit Condyles, Eunice Jungmin Hong

Loma Linda University Electronic Theses, Dissertations & Projects

The present study is a histological evaluation of condyles taken from rabbits that underwent either a midline or paramedian distraction osteogenesis procedure on the mandibles. Fifteen rabbits were originally operated on and eight of these fifteen successfully made it through both the distraction osteogenesis procedure and the 1 month holding period that followed. There was one control animal.

In the present study, the condyles from these nine rabbits (1 control, 2 midline distraction osteogenesis, 6 paramedian distraction osteogenesis) were prepared for histological evaluation (18 total). Step serial sections were cut along the coronal plane and the sections from the anterior …

Healing Following Placement Of A Subperiosteal Orthodontic Anchoring Device, Oliver Hoffmann

Loma Linda University Electronic Theses, Dissertations & Projects

Background: A method to accomplish orthodontic anchorage using a hydroxyapatite-coated disk that is placed below the periosteum in the mid-palatal area has been developed (OnPlant, Nobel Biocare, Yorba Linda, CA, USA). This report describes the early to 8-month healing events of the first 8 consecutive cases of placement of the OnPlant device at the Advanced Periodontics Clinic at Loma Linda University School of Dentistry. In addition, it presents the results of a questionnaire on how the patients experienced the various procedures. A radiographic analysis of the side of placement of the device was performed.

Methods: At 2 weeks and at …

Effect Of Background Synaptic Activity On Excitatory-Postsynaptic Potential-Spike Coupling, Veronika Zsiros

Theses and Dissertations (ETD)

Neurons receive large amount of synaptic inputs in vivo, which may impact the coupling between EPSPs and spikes. We mimicked the in vivo synaptic activity of the cell with the dynamic clamp system. We recorded from pyramidal cells in neocortical slices in vitro to investigate how timing and probability of spike generation in response to an EPSP is affected by background synaptic conductance under these conditions. We found that near threshold, background synaptic conductance improved the precision of spike timing by reducing the depolarization-related prolongation of the EPSP. In cells with ongoing spike activity and background synaptic conductances, an …

Healthcare Strategic Management: The Impact Of State And Federal Funding Levels On The Implementation Of Strategic Plans At Tennessee Hospitals., Randy Lee Byington

Electronic Theses and Dissertations

The purpose of this study was to determine hospital executive management’s perceptions of how turbulence in the politico-legal sector of the macroenvironment impacted the strategic management systems of Tennessee hospitals. In particular, how did Federal and State funding restrictions (Medicare and TennCare) impact the strategic planning and implementation process of their hospitals? The study was also designed to gain insight regarding specific changes to strategic management systems that may have resulted from these funding restrictions.

The research was conducted during April and May of 2003. Data were gathered by surveying the Chief Executive Officers (CEOs) of acute care hospitals in …

Understanding Occupational Therapy: Medical Doctors And Doctors Of Osteopath’S Knowledge About Occupational Therapy In An Acute Care Hospital, Shereen A. Metwalli

Masters Theses

The purpose of this study was to discover whether medical doctors (MD) and doctors of osteopath (DO) at two large hospitals in the Midwest have adequate knowledge about the roles and functions of occupational therapy, its services and benefits to patients and its implications on interdisciplinary team success. Increasing the knowledge in these three areas could influence occupational therapy referral rates and, as a result, impact the quality of patient care. This study used a descriptive survey to collect data from 55 physicians. Respondents acquired their knowledge of occupational therapy through secondary sources within informal sources of information. A statistically …

Dental Treatment Options For Snoring - A Pilot Study, Kainaz Khushrooh Byramjee

Loma Linda University Electronic Theses, Dissertations & Projects

This study compared the effectiveness of an anterior repositioning device, the Silent Nite®, to two new treatments in their ability to stop/reduce snoring. Comfort and side effects of each treatment were also evaluated.

Twenty-three subjects, in good medical condition along with their spouse/partner participated in the five-week study. A disposable sleep apnea screener, SleepStrip,™ was used to select only non-sleep apnea patients. The treatments tested were: (1) Silent Nite® (control - Treatment A), (2) Loma Linda Appliance (Treatment B), and (3) Snore Tape (Treatment C). Each participant received all three treatments separated by a one week "wash-out" period of no …

Data Analysis In The Antes System, Yavuz Tor

Theses and Dissertations - UTB/UTPA

Acanthosis nigricans is a skin condition that can be used as an indicator for the risk of developing type 2 diabetes in the future. Border Health Office, in University of Texas - Pan American, organizes screenings in schools for acanthosis nigricans. Screening results are, then, collected and evaluated in the Border Health Office. The ANTES System is a computer system that stores and manages the data collected in those screenings.

This study is on the analysis of those collected data to track the progress of data entry, to evaluate the progress on obesity and related problems, and to discover the …

Antes: A Web-Based Acanthosis Nigricans And Other Obesity Related Information System, Chunyue Wang

Theses and Dissertations - UTB/UTPA

Acanthosis nigricans is a cutaneous marker associated with systemic disorders and may serve as an indicator for risk of Type 2 diabetes. Acanthosis nigricans screening can help identify children who have high insulin levels and who may be at-risk for developing Type 2 diabetes. The ANTES system is a computerization attempt for acanthosis nigricans control of the student population from elementary schools and secondary schools in Texas. A general description of the system and the medical and history background of the ANTES program is given. The technology applied to the system is demonstrated. An overview of the system operation status …

The Effects Of Hypnosis And Guided Imagery On The Performance Of Track Athletes, Johnathan C. Mossey

All-Inclusive List of Electronic Theses and Dissertations

Although sport psychologists may utilize numerous hypnotic interventions and techniques intended to enhance the performance of athletes, many of these interventions have not been examined by systematic research. This exploratory study examined the effects of interventions using imagery and imagery plus hypnosis on the performance of track athletes. Twenty-nine students from a Midwestern high school track team were randomly assigned to one of two intervention groups: a) imagery and hypnosis or b) an imagery only group. Track team members at another high school served as the control group. The athletes in each group had their performance examined at track meets …

Determination Of The Optimal Form Of A Dna Vaccine To Induce An Effective Immune Response Against A Murine B-Cell Lymphoma, Deepti Aurora

All-Inclusive List of Electronic Theses and Dissertations

Tumor vaccines are a promising alternative to chemotherapy for the treatment of cancer. To be effective and safe, a cancer vaccine should specifically target antigens expressed only on tumor cells. The B-cell tumor-derived Ig receptor may be considered a model tumor antigen for cancer vaccine development. Specifically the immunoglobulin idiotype (ld) encoded by the variable region genes (VH and VL) provides a target antigen. Promising results have been obtained in clinical studies of ld vaccination using ld proteins. However, ld protein is laborious and time-consuming to produce. Gene-based vaccines, on the other hand, are inexpensive and offer ease of manipulation …