Medicine and Health Sciences Commons^™

Healing Through Art: An Exploration Of Art History Influences On Contemporary Art Therapy For Practices In Oncology Care, Nicole Van

Honors Undergraduate Theses

Art therapy has emerged as a vital practice in oncology, offering patients a means of emotional expression and healing during their treatment journey. This project will explore how integrating art history into therapeutic settings, particularly through virtual classes, enhances the emotional well-being of cancer patients. By examining the impact of engaging with historical artworks, this research aims to illustrate how these artistic narratives can facilitate self-consciousness and foster flexibility in individuals facing significant health challenges. Research indicates that exposure to art can evoke emotion and promote psychological healing, serving as a therapeutic outlet for patients. This study will synthesize therapeutic …

Evaluating Coffee And Caffeine Intake In Adults With Cardiovascular Disease: A Comparative Literature Review, Adam Harrington

Honors Undergraduate Theses

Coffee is among the most commonly consumed beverages worldwide, and its bioactive components, including caffeine, affect the cardiovascular system through multiple physiological mechanisms. Patients with cardiovascular disease are typically advised to limit coffee and caffeine consumption because of potential cardiovascular harm, but emerging research challenges this recommendation. This review evaluates recent evidence regarding consumption of whole coffee, caffeine, or decaffeinated coffee in adults with established cardiovascular disease. Database searches conducted across three platforms for studies published after December 2021 yielded 360 records. Following screening against inclusion criteria, 11 studies were reviewed included in the final review. The studies showed variable …

Factors Associated With Fatalism Among Hispanic And Latina Breast Cancer Survivors, Liara Lopez Torralba

Honors Undergraduate Theses

As fatalism, a person’s attitude towards their life, increases, there is a significant level of medical mistrust and avoidance, which can delay cancer diagnoses and affect the prognosis of the disease. Literature has shown that many factors, including age, race, acculturation, locus of control, education, and fear can influence fatalism. However, little research has been conducted on whether fatalism differs independently by Hispanic origin and its associated factors among Hispanic breast cancer survivors. This study used data from the Hispanic Breast Cancer Study at the University of Central Florida. The original study recruited 408 women aged ≥ 20 years, diagnosed …

Examining The Best Dietary And Lifestyle Interventions To Prevent Hyperinsulinemia And Insulin Resistance In Women With Polycystic Ovarian Syndrome, Erica C. Morman

Honors Undergraduate Theses

Polycystic Ovarian Syndrome (PCOS) is a complex reproductive and metabolic disorder that affects up to 15% of women, contributing to insulin resistance, hyperinsulinemia, risk for developing type 2 diabetes. The interconnected hormonal and metabolic disruptions in PCOS create a feedback loop that exacerbates symptoms, making dietary and exercise interventions critical in its management. This literature review evaluates the efficacy of various dietary interventions including the ketogenic diet, high-protein diet, low-carbohydrate diet, and high-fiber diet, as well as exercise interventions such as high-intensity interval training (HIIT), resistance training, and moderate-intensity aerobic exercise. Results found that modifying carbohydrate intake, and increasing fiber …

Facilitation Of Chemotherapy Efficacy Through Targeted Drug Delivery In Lung Cancer Cells Via Ultrasound And Implications On Health Interventions, Ibrahim Nasim

Honors Undergraduate Theses

Lung Cancer (small cell and non-small cell) is the leading cause of cancer death in the US, accounting for about 20% of all cancer deaths. Paclitaxel (PTX) is a chemotherapeutic agent commonly used to treat lung cancer. It works by slowing and stopping cancer growth by stiffening microtubules within cells, promoting mitotic halt and cell death. Carboplatin (CP) is another agent given to lung cancer patients containing platinum and works via direct damage of oncolytic DNA. The exact mechanism of how PTX and CP cause cell death is still an under-studied area. This thesis aims to provide insight into how …

Investigating The Effect Of Artificial Sweeteners On Fitness And Metastasis In Drosophila Melanogaster, Om R. Patel

Honors Undergraduate Theses

Artificial sweeteners are widely used sugar substitutes, yet their potential effects on health remain poorly understood. For example, more evidence suggests that frequent consumers of sugar substitutes may also be at increased risk of excessive weight gain, metabolic syndrome, and type 2 diabetes, which contradicts the original purpose of artificial sweeteners. This thesis investigates the impact of artificial sweeteners on health using Drosophila melanogaster as a model organism, focusing on three key areas: viability, excretion, and cancer metastasis. Viability assays revealed that flies exposed to artificial sweeteners exhibited a decrease in progeny, with some concentrations increasing progeny but most decreasing …

Family Perceptions Of End-Of-Life Care For Terminally Ill Individuals In The Intensive Care Unit, Yunju Kim

Honors Undergraduate Theses

The Intensive Care Unit (ICU) provides specialized care for critically ill individuals, but despite aggressive treatments, the risk of mortality remains high. Transitioning from life-saving interventions to end-of-life care (EoLC) can be emotionally challenging for families and the healthcare team. Fear of EoLC can lead to a continuation of futile treatments, leading to ethical conflicts, emotional distress, and unnecessary suffering. The primary purpose of this literature review is to explore incongruencies in family expectations for EoLC in terminally ill individuals in the ICU in the transition of care from life-saving measures to EoLC. The secondary purpose of this literature review …

The Effects Of Nurse-Led Physical Activity On The Aging Population, Kaitlyn P. Carruba

Honors Undergraduate Theses

The aging population in the United States is increasing in proportion, yet older adults' physical activity levels have not increased much. The lack of physical activity leads to numerous health complications, such as an increased risk for cardiovascular disease, increased risk for falls and fractures, as well as lead to obesity and diabetes. Unfortunately, few healthcare facilities monitor or audit physical activity. Older adults are frequently placed on fall risk precautions, which heavily encourages a sedentary hospital stay. This commonly leads to older adults with declining abilities to accomplish their activities of daily living (ADLs) after hospitalization. Nurses, spending the …

From Tricare To Medicaid: Dental Insurance Disparities Among U.S. Veterans And Active Duty Service Members, Madeline K. Mcnutt Ms

Honors Undergraduate Theses

Oral health plays a critical role in systemic well-being, yet dental care access in the United States remains deeply unequal, particularly among low-income and historically marginalized populations. Among those significantly affected are military veterans, who frequently experience barriers to oral healthcare due to eligibility restrictions within the Department of Veterans Affairs (VA) system. This study offers a comparative analysis of dental insurance satisfaction between recipients of Medicaid and the TRICARE Active Duty Dental Program (ADDP), two federally funded programs that reflect the divide between civilian and military healthcare access. While TRICARE ADDP provides comprehensive and uniform coverage for Active Duty …

The Effectiveness Of Trauma-Informed Care Education On The Self-Efficacy Of Pediatric Nurses: An Integrative Literature Review, Mackenzi N. King

Honors Undergraduate Theses

Pediatric nurses often care for patients who have experienced various forms of trauma, including medical traumatic stress, abusive head trauma, child maltreatment, and sex trafficking. Trauma-informed care (TIC) is a clinical approach that acknowledges the psychological and physical effects of trauma, supports the identification of trauma survivors, and seeks to prevent re-traumatization during healthcare encounters. Research has highlighted the need to improve nurses' self-efficacy in delivering TIC effectively. This integrative literature review explores the impact of TIC training on pediatric nurses’ knowledge, confidence, and competence in providing TIC. A comprehensive literature search was conducted using CINAHL Ultimate, APA PsychInfo, and …

A Systematic Review Of Dietary Trends, Influencing Factors, And Their Impacts On Cardiovascular Health In Turkish Populations, Pelin L. Özoğlu

Honors Undergraduate Theses

Cardiovascular disease (CVD) is the leading cause of death globally, including in Türkiye. One key factor influencing CVD prevention is dietary patterns, which directly impacts cardiovascular health. Türkiye traditionally follows the Mediterranean diet (MedDiet), which is acclaimed for its cardiovascular benefits. Despite this, Türkiye continues to experience high rates of CVD, with projections indicating that CVD mortality will double for both men and women by 2030. It is crucial to address diet-related factors, including potential nutritional deficiencies, to reduce cardiovascular health risks.

This research aims to analyze the Turkish community's adherence to the Mediterranean diet to understand why CVD prevalence …

Improving Safe And Effective Management Of Pain At Home, Alayna V. Olivarez

Honors Undergraduate Theses

Pain is the most common clinical symptom in individuals with a cancer diagnosis. Additionally, home is the preferred place for cancer care which introduces numerous challenges for cancer pain management. The primary purpose of this literature review is to identify support interventions to enhance pain control, prevent exacerbations in pain, and optimize quality of life in individuals with cancer transitioning from the acute care setting to home. The secondary purpose of this review is to analyze patient-specific barriers influencing self-efficacy of pain management and overall health outcomes in the target population. A systematic literature search was conducted using CINAHL, EBSCOhost, …

The Effects Of School-Based Menstruation Education Programs On Anxiety And Self-Efficacy In Adolescent Girls: A Systematic Review, Hannah C. Hart

Honors Undergraduate Theses

A significant global knowledge gap exists for adolescent girls regarding what constitutes a healthy menstrual cycle, proper menstrual hygiene practices, and the implications of reproductive maturity that is ushered in by menarche. This limited understanding can lead to poor health outcomes and the development of negative sentiments and beliefs surrounding the normal experience of menstruation.

This systematic review aims to comprehensively investigate the current state of research regarding the effects of school-based, formal menstruation education programs on adolescent girls, particularly the effects on anxiety and self-efficacy related to the management of menstruation. Furthermore, this work aims to take a stance …

Cultural Competence In Pre-Medical Education: Examining Preparedness For Cross-Cultural Care, Fiza N. Khan

Honors Undergraduate Theses

As the U.S. population continues to grow more diverse, there is an urgent need for future healthcare providers to develop strong cultural competence. This study investigates undergraduate pre-medical students’ knowledge, attitudes, and comfort levels toward caring for diverse patient populations, including immigrants, refugees, and individuals from varied cultural backgrounds. The goal was to assess how well students are prepared to provide culturally responsive care before entering medical school. Recognizing that the foundation for medical training begins at the undergraduate level, this study aims to identify specific gaps in readiness that may hinder equitable patient care in the future.

A modified …

Meta-Analysis Of The Effect Of Vagus Nerve Stimulation On Functional Heart Failure Outcomes, Ariana B. Labrada

Honors Undergraduate Theses

Globally, Heart Failure (HF) is a significant cause for concern. Vagus Nerve Stimulation (VNS) is an emerging therapy for patients with HF. It involves the activation of efferent vagal signals, which result in the release of acetylcholine (ACh). In practice, VNS has obtained relatively mixed results in clinical trials so far. In order to ascertain the extent of the effects VNS has on functional clinical outcomes, this meta-analysis consolidates studies that involve patients with Heart Failure with reduced Ejection Fraction (HFrEF) and Heart Failure with preserved Ejection Fraction (HFpEF). Outcomes were measured through the change in mean heart rate (HR) …

Genomic Epidemiology Of Staphylococcus Aureus Sequence-Type 72, Sachitaa Senthilkumar

Honors Undergraduate Theses

Staphylococcus aureus (S. aureus, SA) is a gram-positive bacterial colonizer and pathogen commonly carried on the skin and in the anterior nares of humans. SA colonization may lead to a variety of non-invasive (e.g., skin and soft tissue infections, SSTIs) and invasive (e.g., bacteremia and osteomyelitis) infections. The SA population is comprised of multiple lineages that can be delineated through multi-locus sequence typing (MLST), which compares nucleotide sequences within seven housekeeping genes. Strains belonging to an MLST share a common evolutionary history and phenotypic characteristics like antibiotic resistance or virulence. As a result, the epidemiology of lineages can be …

High-Throughput Drug Screening For Disease-Modifying Arthritis Therapy, Janapriya Vijayakumar

Honors Undergraduate Theses

Current therapy for arthritis predominantly focuses on the symptoms rather than the underlying causes of disease progression. Thus, it is necessary to identify novel drugs which target the underlying molecular basis of such diseases. Using high-throughput cell-based drug screening, we screened 458 different compounds, narrowed down from 811 starting compounds from the NIH Mechanistic Set. We selected drugs from the Mechanistic Set following Lipinski's Rule of 5 to ensure optimal pharmacokinetic properties. The study used modified primary human chondrocytes (IIAM-PRG4Luc), which secrete a lubricin promoter-driven luciferase reporter. We use this luciferase expression as a proxy to measure lubricin, a compound …

Investigation Of Lubricin-Stimulating Fda-Approved Compounds For A Disease-Modifying Osteoarthritic Drug, Swathi S. Menon

Honors Undergraduate Theses

Osteoarthritis (OA) is a degenerative disease that affects many people worldwide. Current methods of treatment are palliative, and no treatment exists to fully reverse or cure OA once it begins to progress. The discovery of a disease-modifying osteoarthritic drug (DMOAD) would increase the quality of life for millions and reduce the need for invasive procedures. Screening FDA-approved drugs ensures more promise due to their known safety profile and potential for faster translation to the clinic. The goal of this project was to conduct dose-response assays with FDA-approved drugs that have been shown to stimulate lubricin production in cells that mimic …

Development Of A Proposed Selective Medium For The Isolation And Differentiation Of P. Sordellii, Dimyana Bottros

Honors Undergraduate Theses

Clostridium, a genus of anaerobic, spore-forming bacteria, includes clinically and ecologically significant species like Clostridium difficile and Paeniclostridium sordellii. C. difficile causes antibiotic-associated colitis, while P. sordellii is linked to fatal infections and spontaneous abortions. Recent studies found both species in marine sediments, suggesting their role in environmental and wildlife health disturbances, including the 2013 mass mortality of over 300 manatees in the Indian River Lagoon. However, isolating and differentiating P. sordellii is challenging due to the lack of selective media optimized for its growth. This thesis proposes a novel selective medium tailored to P. sordellii’s physiological …

“Regression To The Mean”: The Confluence Of Eugenics And Statistics In The 19th And 20th Centuries, Emrys G. King

Pomona Senior Theses

The work of this thesis is twofold — first, qualitatively characterizing the confluence between the British eugenics and statistics movements in the late 19th and early 20th centuries, and second, quantitatively analyzing the effect of this foundation on pedagogical materials in the growing field of statistics between 1880 and 1970. Towards the first goal, the history of the method of least squares, state statistics, and positive and negative eugenics are outlined, followed by a close reading of the foundational texts authored by Francis Galton and Karl Pearson that introduced linear regression. Towards the latter goal, English-language statistics textbooks published between …

Biomechanics Of The Atherosclerotic Lipidome: (Un)Expected Statin Interactions And Membrane Remodelling, Ethan M. Fong

Pomona Senior Theses

Statins interact with lipid membranes in ways that shape their pharmacokinetics, off-target effects, and pleiotropic actions, yet these interactions' mechanical and biophysical consequences remain poorly understood. This thesis employs a combination of surface plasmon resonance (SPR), quartz crystal microbalance with dissipation monitoring (QCM-D), and rheological modelling to characterize how representative statins intercalate within biomimetic supported lipid bilayers (SLBs) of healthy and diseased composition. SPR reveals that lipophilic statins exhibit higher apparent affinities and slower dissociation kinetics, especially in cholesterol- and anionic lipid-rich membranes. QCM-D analyses demonstrate that statins alter membrane mass, dissipation, and interfacial stiffness in a statin- and membrane-dependent …

One Man Show/ Who Am I, Devin Baker

Dance (MFA) Theses

Historically, stereotypes of ideal masculine physiques and attributed qualities have led to discriminatory and exclusionary practices that adversely affect black queer men and how they show up in various performance and social spaces. As a result, black male bodies in these spaces have employed the alter ego as a tool to imagine themselves inside/outside these constructed masculinities. How can the alter ego aid in transcending dated notions of race and gender, beholden to black male bodies within concert dance? Through the intertwining of personal narrative and research rooted in psychology and gender studies, this work examines the alter ego as …

The Implementation Of The Queensland Health Smoking Cessation Clinical Pathway In A Western Australian Private Hospital Setting: A Feasibility, Leah Jane Epton

Theses

As smoking is prohibited on most hospital grounds, hospitalisation presents a valuable opportunity for healthcare professionals to identify smokers, administer smoking cessation treatments, and ensure appropriate inpatient support, as well as continued follow-up on discharge. It has been reported both anecdotally and in published research that encouragement from a health professional is a significant external prompt for a smoker to attempt quitting. It has also been noted in the inpatient setting, one in every 33 conversations will lead to the successful cessation of smoking.

More broadly, a 2012 Cochrane review on smoking cessation interventions for inpatients identified that they are …

Defining Barriers In Pulmonary Hypertension: Pulmonary Hypertension In Remote And Rural Settings In Australia: An Epidemiologic Study Aided By Echocardiography, Pyi Naing

Theses

Pulmonary hypertension (PH) is a common, complex, and potentially lethal haemodynamic condition with many underlying aetiologies. It is poorly understood, and diagnosis is usually made late in the disease process resulting in poor outcomes even in the developed world. An innovative universal framework is required to achieve early and accurate diagnosis for improved outcomes, especially in remote and rural areas. The thesis documents my substantial body of work that unlocks a collective framework to assist patients with PH, particularly in areas not classically serviced by tertiary level PH care.

The first chapter of my thesis outlines the history, important milestones …

The Effect Of Woc Nurse Rounding On At-Risk Patients In The Icu In Reducing Hapis: An Integrative Review, Sydney Conrad, Ayoka Allen, Abby Fitzpatrick, Raquel Luague, Emily Lindall

Master's Projects

Hospital-acquired pressure Injuries (HAPIs) are a “never event” and a nursing quality indicator closely monitored by hospitals. Pressure injury prevention strategies have been widely researched and used to reduce HAPI rates; however, despite this research, HAPI rates, especially in the intensive care unit (ICU), remain high. Prevention is a complex, individualized process that requires nursing understanding and application. Wound, Ostomy, and Continence nurses (WOC nurses) are specially trained and certified in wound management and can provide tremendous clinical insight into risk and prevention factors. This integrative review examines whether WOC nurse rounding in the ICU reduces HAPI rates.

Neighbourhood Resilience Planning With Renters In Hamilton, Ontario, Canada, Anna Do

Theses and Dissertations (Comprehensive)

This sequential mixed-methods study demonstrates the co-production of knowledge between academic researchers and local communities. Guided by the resilience planning framework, the study engaged 48 renters from the Beasley neighbourhood of Hamilton, Ontario, Canada in identifying stressful and supportive locations using a participatory mapping tool called the “Place Report.” A total of 74 Place Reports were submitted, with most reporting supportive places in or near Beasley. Thematic analysis revealed three overarching domains, and 13 themes related to the use and function of these locations. Places pertaining to food, housing, and physical activity emerged as the most frequently discussed topics. The …

Exploring Laurier Health Sciences Students’ Knowledge Of Lgbtq+ Health, Grace Emma Henry, Todd Coleman

Theses and Dissertations (Comprehensive)

In all health-related fields, the need for well-informed, holistic healthcare providers is paramount. For the heathcare field to be impactful in positive ways, providers should emerge from multifaceted academic backgrounds, equipped with an array of knowledge and skills to address the complex needs of different patients. Central to this is the idea that all aspects of an individual's identity and the intersectionality of these identities should be considered when providing care. Intersectionality recognizes that various social and personal identities, such as race, gender, sexuality, and socioeconomic status, intersect to shape individual experiences and health outcomes (Kelly et al., 2022).

Lesbian, …

Immune Pathway Modulation In Melanoma Using Chitosan Nanoparticle-Mediated Dsrna Delivery, Bethel C. Iwuji

Theses and Dissertations (Comprehensive)

Cancer is a group of diseases characterized by abnormal and uncontrolled cell division, which typically results in the formation of tumours. Even with advances in treatments, cancer remains one of the leading causes of death globally. Melanoma is an aggressive form of skin cancer which is highly malignant, develops in the pigment-producing cells of the skin, melanocytes, and in the late stages of the disease poses a significant challenge for therapeutic intervention due to its multidrug resistance. The innate immune system is the first line of defence against invading pathogens, including viruses, bacteria, and fungi, and can recognize and destroy …

London's Murderous Mothers: How Charitable And Medical Advancement Influenced Infanticide Indictments During The Long 18th Century, Brandon Gamman

EWU Masters Thesis Collection

No abstract provided.

Health Center Patient Satisfaction: Pre, During, And Post Covid-19, Patricia A. Stroup, Patricia Stroup

West Chester University Graduate Theses, Dissertations, and Final Projects

This study aims to evaluate patients' attitudes toward healthcare services in a predominantly Hispanic population at an urban health center serving a significantly disadvantaged population.  This center is in one of the poorest areas of the city and has one of the highest diabetes rates in the nation. For over 50 years, Federal health centers have provided care to inner-city, rural, homeless and public housing residents. They provide care to vulnerable populations that would not otherwise be available in medically underserved communities. Central to overcoming disparities is assuring patient satisfaction with their healthcare. This study evaluates patients' satisfaction with the …