Medicine and Health Sciences Commons^™

Investigating The Relationship Between Drug Overdose Deaths, Excessive Alcohol Drinking, And Adult Smoking In Urban And Rural Ohio Counties In 2025, Sumin Byoun, Anne Griffin

Scholarship in Medicine - All Papers

Deaths from drug overdoses have been increasing each year. Ohio ranks among states with the highest number of drug overdose deaths per year. There is a gap in the literature regarding discussions of how excessive alcohol drinking and cigarette smoking rates may predict drug overdose death rates in a community. First, this study investigates differences in excessive drinking, adult smoking, and drug overdose deaths between urban and rural counties in Ohio. Second, this study explores whether excessive drinking and smoking behaviors can predict drug overdose death rates in urban and rural Ohio counties. Data exclusive to Ohio counties was obtained …

Understanding The Impacts Of Food Insecurity On Education Outcomes In Ohio, Maria El Biri, Sreya Tummalapalli

Scholarship in Medicine - All Papers

Background: Food insecurity has been a growing concern in the United States, and prior research has shown how food insecurity in youth can correspond to negative psychosocial outcomes. Additionally, there are known disparities with access to food based on living in rural or urban counties. Objective: The goal of this study was to determine how differences in food security can impact youth educational outcomes in Ohio. Methods: Data from County Health Rankings & Roadmaps were obtained on variables such as access to healthy foods, food insecurity, high school graduation rates, average grade performance, and percentage of the population living in …

Infant Mortality In Ohio, Isabella Bacon, Alexis Jackson

Scholarship in Medicine - All Papers

Introduction: Infant mortality continues to occur at alarming rates that differ among various groups and states. Despite this, there has been a lack of intersectional examination of risk- and protective-factors. Methods: We examine how smoking status, education level, primary care to population ratio, teen birth rates, and urban vs rural status impact infant mortality rates in Ohio, Kentucky, Michigan, and Indiana using County Health Rankings data. Results: Ohio was shown to have no significant difference between urban and rural infant mortality rates; however,  risk-and-protective factors did differ. In urban counties, high school completion, teen birth rates, and primary care ratios …

Voice Your Choice, Sarah Olson, Mercy Bustamante-Vizarretea, Hannah Bauman, Sally Hall

SPARK Symposium Presentations

Our proposal seeks to develop and implement a standardized Charge Nurse Interest Survey which will create a structured process for identifying those most interested and best suited for the position of charge for all registered nurses on a local med-surg unit. Nurses on this unit are appointed and eligible to serve in the charge nurse role after six months of experience on the unit. Research shows that charge nurses who demonstrate emotional stability, composure under pressure, strong organizational skills, and proactive planning contribute to improved team functioning and decreased workplace strain (Gottlieb & Gøtzsche-Astrup, 2018).

To clarify the charge nurse …

Accuracy Of The Nestlé Mini Nutritional Assessment® (Mna®) Screen In Identifying Prealbumin–Defined Malnutrition Amongst Spine Surgery Patients, Stylianos Mysirlidis, Luke Fischbach, Matthew Giammanco, Alex Zhang, Phillip Alexeev, Ryan Snowden

SPARK Symposium Presentations

Abstract:

Background:

Malnutrition is a significant risk factor for patients undergoing surgery, including those receiving spine surgery. These patients are at greater risk of adverse postoperative outcomes, impaired wound healing, and spinal fusion failure. Therefore, it is essential to identify at-risk, malnourished patients prior to intervention to mitigate any complications such as surgical site infections, unplanned readmissions, and reoperations. The primary focus of this study was to assess the accuracy of the Nestlé Mini Nutritional Assessment® (MNA®) on identifying true malnutrition amongst those patients undergoing spine surgery.

Methods:

We conducted a retrospective cohort study of 674 consecutive …

The Relationship Between Phone Usage, Activity Participation, And Hand Strength, Debra Gibbs, Will Best, Raegan Adams, Amanda Finke, Rachel Pierce, Salem Swallows, Alisha Yoo

SPARK Symposium Presentations

Smartphone use among university students in the United States is steadily increasing. Longer duration of smartphone use has been associated with increased risk of smartphone addiction, reduced musculoskeletal strength, and engagement in meaningful activities. While prior research has examined these variables separately, limited evidence exists on the associations between smartphone use, hand grip and pinch strength, and extracurricular and leisure activities among U.S. university students. To address this gap, a correlational study was conducted using the Spearman rank correlation to analyze the relationship between phone use, activity participation, and hand strength. A Qualtrics survey including demographic information, phone usage, and …

Slow Your Pace; Do I-Trace!, Meghan Delaney, Mckenna Geary, Kacie Knary, Chloe Minnich

SPARK Symposium Presentations

SPARK Final Summary

Slow your pace; do I-TRACE! The purpose of this project is the addition of the I-TRACE method to strengthen the current strategies and practices with a long-term goal of reducing central line associated bloodstream infections (CLABSI) events. CLABSI remains an ICU concern, with an estimated 15,000 cases annually in the U.S. (NHSN, 2026). In 2025, a local ICU reported seven CLABSI events, an unusually high number for one hospital (LeapFrog, 2016). To combat CLABSIs, we will implement the I-TRACE method during every hand-off. The oncoming nurse will assess all central lines and dressings, and both nurses will …

The Impact Of An Aquatic Exercise Program On Self-Reported Balance And Confidence On Perceived Fall Risk: A Pilot Study, Antoney Labuschagne, Wesley Hopper, Bailey Watson, Alexis Ignatin, Ashtyn South, Whitney Dupree, Natalie Michaels

SPARK Symposium Presentations

Background: Each year, thousands of people experience one or more episodes of falling, that lead to a lasting impact in function and participation in daily life. Education regarding fall prevention is often focused mainly on the older adult population, but falls can happen at any age. Fear of falling and pain-related fear exists among adults at any age. The focus of this research study was to determine if participation in an aquatic exercise program that focused on balance, core body strength, and cardiopulmonary endurance could be utilized to alleviate the fear of falling and improve performance. Methods: Eight participants completed …

Investigating The Role Of Humic Acid In The Adsorption Mechanics Of Acetaminophen On Potassium Persulfate-Aged Polyethylene Terephthalate (Pet), Andrew Littleton, Maria Danielle Garrett, Phd

SPARK Symposium Presentations

Pharmaceutical contaminants such as acetaminophen (APAP) are showing a rising presence in aquatic environments, where their interactions with microplastics (MPs) can potentially modulate natural degradation mechanisms. Concurrent presence of the two substances has been shown to potentiate increase their individual harmful effects. This study investigates whether oxidative aging and humic-acid surface modification of PET microplastics influence APAP adsorption.

In this study, UV-aging was reproduced using an iron (II)-activated potassium persulfate (Fe(II)-KPS) oxidation system. Aqueous dissolved organic matter (DOM) is simulated using multi-hour exposure to humic acid. The MPs are then removed from the solution to examine adsorption mechanisms. While most …

Don't Let Them Fall, Let Ai Call, Ella Mills, Sara Barker, Andreea Ifrim, Yvette Uwase

SPARK Symposium Presentations

This project proposes a nurse-led pilot of AI-supported predictive mobility monitoring on a cardiac medical-surgical unit, to improve early identification of high-risk mobility behaviors and enhance patient safety. Current fall-prevention strategies, such as bed alarms and virtual sitters, often alert staff after unsafe movement has begun, creating a reactive cycle that contributes to alarm fatigue and delayed intervention (Abbe & O’Keeffe, 2020). This initiative uses monitors with contactless infrared sensors to identify movement before patients exit the bed, an alert system that goes straight to the nurse and PCT phones, and a central console for floor management and care coordination. …

Assessment Of Doxorubicin And Etoposide Effects On Cardiotoxicity Using Daphnia Magna As A Model Organism​, Jacob P. Bealle, Andrea Florian

SPARK Symposium Presentations

Chemotherapeutic agents such as doxorubicin and etoposide are widely used in cancer treatment but are known to produce cardiotoxic side effects that can limit their clinical use. Doxorubicin has been strongly associated with dose-dependent cardiac damage, and etoposide has also been reported to produce cardiotoxic effects although the cardiotoxic effects of etoposide are not as well studied. Daphnia magna is a useful model organism for cardiotoxicity studies because its transparent body allows direct observation of heart rate and provides a living system for detecting physiological responses to exposure. The purpose of this study was to investigate the cardiotoxic effects of …

Potential Environmental Triggers Of Goodpasture's Disease And The Role Of The Sulfimine Crosslink, Colton S. Miller, Andrea Florian, Elena Pokidysheva

SPARK Symposium Presentations

Goodpasture’s syndrome (GP) is an autoimmune disorder that primarily affects kidneys and lungs. The main issue for patients with Goodpasture's syndrome is the binding of autoantibodies to the glomerular basement membrane (GBM), which hinders the filtration of blood. A key characteristic of Goodpasture's syndrome is the presence of autoantibodies that target the NC1 domain of the α345 isoform of type IV collagen, a crucial component of the GBM that provides structural support and is critical for filtration function. Sulfilimine bonds crosslink the collagen IV NC1 hexamers, contributing to the stabilization of these structures. A recent clinical case of recurring Goodpasture's …

A Review Of Replications Over 88 Years Of The American Speech-Language Hearing Association Journal Publications, Andrea L.B. Ford, Jessica S. Riccardi, Austin Thompson, Helen L. Long, James C. Borders, Scott R. Schroeder, Alisa Baron, Mariam El Amin, Danika L. Pfeiffer

Speech-Language Pathology Faculty Publications

Purpose: This review aimed to determine the prevalence of replication studies in the field of Communication Sciences and Disorders and examine longitudinal changes in this prevalence across American Speech-Language-Hearing Association (ASHA) journals from 1936 to 2024. It is a conceptual replication of Cook and colleagues' review of replications in special education journals.

Method: Our data source comprised 17,843 journal articles published in seven ASHA peer-reviewed journals between 1936 and 2024. We identified 3,903 articles, excluding duplicates, that had at least one instance of replicat*. Two research team members screened articles independently, and then one research team member coded each article, …

Understanding Autonomous Sensory Meridian Response (Asmr), Cecilia Zoutewelle

A. The Science of Sound

This 7-page report with illustrations and bullet-point summaries provides an introduction to the phenomena of Autonomous Sensory Meridian Response (ASMR). Also included is a brief discussion on the benefits of ASMR for interpersonal listening.

Fuel Your Focus: The Improtance Of Diet For Listening, Lauren Martins

A. The Science of Sound

This infographic presents an overview of the importance of diet for listening. Foods affect energy, memory, concentration, and other factors that influence listening.

Existential Intelligence: A Survey Across The Ages--As Well As My Ages, Howard Gardner

International Journal of Transpersonal Studies Advance Publication Archive

Written in response to Branton Shearer’s (2026) paper on existential intelligence and existential reasoning, this paper argues that due to the lack of evidence of neural specialization and a developmental trajectory, pondering existential questions is best understood as philosophical thinking, rather than a distinct intelligence. The paper reflects on the status of existential thinking within the author’s framework for multiple intelligences. It traces the criteria originally used to identify the author’s seven intelligences, the later admission of naturalist intelligence, and the provisional consideration of pedagogical and existential intelligences. The paper explains why the labels “spiritual” and “religious” intelligence have been …

Maslow’S Hammer: The Problem Of Scientism And The Philosophy Of Science In Maslow’S Later Work, Richard Grego

International Journal of Transpersonal Studies Advance Publication Archive

This paper examines how Abraham Maslow’s concern with the pervasive intellectual and cultural influence of scientism shaped his philosophy of science and anticipated contemporary discourse on the nature of scientism. Although he never articulated a thorough, formal, or systematic philosophy of science, Maslow’s conception of science’s nature and scope is evident through the course of his work, and it was shaped by his concern with the emerging influence of scientism. The prominent intellectual status science has enjoyed since the Enlightenment has made scientism a powerful influence on postmodern intellectual and popular culture that is currently the subject of a wide …

Revisiting The Life Cycle Of Margalefidinium Polykrikoides Group Iii, Eduardo Pérez-Vega, Kenneth N. Mertens, Pjotr Meyvisch, Margaret R. Mulholland

OES Faculty Publications

Dinoflagellates produce cysts as a strategy to withstand environmental stressors, with nutrient depletion generally considered a key trigger for cyst production. Resting cysts are thick-walled, typically composed of one to several layers, and characterized by a prolonged dormancy period. In contrast, pellicle cysts possess a thin, single wall and exhibit no dormancy or a markedly shorter dormancy than resting cysts of the same species. Margalefidinium polykrikoides produces pellicle and resting cysts, whereas its congener, M. fulvescens, has been shown to produce pumpkin-like structures. Using phase-contrast microscopy, time-lapse microscopy, FlowCam, and attenuated total reflection Fourier transform infrared microspectroscopy (ATR μ-FTIR), …

From Reactionary To Anticipatory Integrated Action: Novel Environmental Health Surveillance For Mass Gatherings, Benjamin J. Ryan, Michael Donahoo, Danielle Esler, Paul Barach, Benjamin Coghlan, Shelby Garner, Laura M. Langan, John Piispanen, Bryan W. Brooks

College of Population Health Faculty Papers

Advances in AI-driven analytics, human-in-the loop techniques, and wastewater monitoring provide the foundation needed to shift from reactive to anticipatory actions for mass gatherings. Traditional surveillance systems focus on clinical and laboratory-based notification pathways, which often result in tardy actions being implemented. Thus, traditional surveillance is becoming outdated. Mass gatherings pose heightened public health risks and hazards, including trauma; injury and substance misuse; deliberate poisoning; and infectious diseases such as food and waterborne illnesses, sexually transmitted infections, and respiratory diseases. There is also a heightened concern due to reduced vaccination coverage. As a result, future international events such as the …

Conventional Versus Advanced Imaging Selection For Endovascular Treatment Of Basilar Artery Occlusion Strokes., Huanwen Chen, Marco Colasurdo, Hidetoshi Matsukawa, Conor Cunningham, Ilko Maier, Sami Al Kasab, Pascal Jabbour, Joon-Tae Kim, Stacey Quintero Wolfe, Ansaar Rai, Robert M. Starke, Marios-Nikos Psychogios, Edgar A. Samaniego, Nitin Goyal, Shinichi Yoshimura, Hugo Cuellar, Jonathan A. Grossberg, Ali Alawieh, Ali Alaraj, Mohamad Ezzeldin, Daniele G. Romano, Omar Tanweer, Justin Mascitelli, Isabel Fragata, Adam Polifka, Fazeel Siddiqui, Joshua Osbun, Roberto Crosa, Charles Matouk, Min S. Park, Michael R. Levitt, Waleed Brinjikji, Mark Moss, Travis Dumont, Ergun Daglioglu, Richard Williamson, Pedro Navia, Reade De Leacy, Shakeel Chowdhry, David J. Altschul, Alejandro M. Spiotta, Peter Kan

Department of Medicine Faculty Papers

INTRODUCTION: Endovascular thrombectomy (EVT) is an effective treatment for basilar artery occlusion (BAO) stroke in select patients. While there is a growing body of literature suggesting that advanced imaging modalities such as computed tomography perfusion (CTP) and magnetic resonance (MR) may not be necessary for selecting anterior circulation large vessel occlusion stroke patients for EVT, whether advanced imaging may be superior to conventional imaging (non-contrast CT and CT angiography) in identifying good treatment candidates among BAO patients is less clear.

PATIENTS AND METHODS: This was a multicenter retrospective cohort study of BAO EVT patients treated from 2013 to 2022 in …

Digital Cognitive Behavioral Therapy Versus Education For Chronic Pain In Adults With Sickle Cell Disease: 12-Month Randomized Trial Results, Olubusola B. Oluwole, Yi-Fan Yi-Fan Chen, Christina M. Lalama, Julia A. O’Brien, Laura M. De Castro, Charles Patrick Carroll, Darla Liles, Nirmish Shah, Santosh L. Saraf, Victor R. Gordeuk, Leshana Saint Jean, Michael Debaun, Robert M. Cronin, Tonya M. Palermo, Sherif M. Badawy, Megan E. Hamm, Jennifer N. Stinson, Chitra Lalloo, Sophie Lanzkron, Cassandra Trimnell, Lakiea Bailey, Raymona H. Lawrence, Kaleab Z. Abebe, Charles R. Jonassaint

Department of Medicine Faculty Papers

Background: Chronic pain affects up to 40% of adults with sickle cell disease (SCD), yet treatment options remain limited. While cognitive behavioral therapy (CBT) is effective in other chronic pain conditions, it is underutilized for SCD pain, and its effectiveness remains unclear. Purpose: The Cognitive Behavioral Therapy and Real-time Pain Management Intervention for Sickle Cell via Mobile Applications (CaRISMA) compared digital CBT to Education for chronic SCD pain in adults. At 6 months, the primary outcome (pain interference) showed no between-group difference but both groups improved (CBT: −2.13; Education: −2.66). This report presents 12-month outcomes. Methods: A total of 359 …

Managing Complexity: Manager-Stakeholder Communication, Relational Dynamics, And The Dual Nature Of Rtw Communication, H. Bertolini, Marc Corbière, Alessia Negrini, Nadine Larivière, Patrizia Villotti, Dominic Prévost, Meryl Caiada, Jason Amorim, Fergal O'Hagan

Études primaires

Purpose

The return to work (RTW) process of worker absent due to common mental disorders (CMD) or musculoskeletal disorders (MSD) represents a complex challenge that involves multiple stakeholders. The aim of this study was to examine how managers perceive the factors that facilitate or hinder communication with other stakeholders during the RTW process.

This qualitative study was based on four focus groups conducted in Canada (Quebec and Ontario) with 18 managers.

Thematic analysis identified five themes related to facilitators and seven themes related to communication obstacles. Among the main facilitators, trust, clarity, and collaboration emerged as key elements …

If Only Pickups And Vans Could Fly: Vehicle Maintenance And The Challenge Of Safely Lifting Large Vehicles On A Two-Post Lift, Damien Burlet-Vienney, Sylvie Beaugrand, Maud Gonella, Bertrand Galy, Élise Ledoux

Études primaires

The use of automotive lifts requires mechanics to work under or near a multi-ton load. Based on consultation with stakeholders, pickups and vans appear to pose problems when raised using two-post above-ground lifts (2PAG lifts), the most common type of automotive lift in garages. The aim of this study is therefore to highlight the work activity performed by mechanics when raising pickups and vans on 2PAG lifts and to describe the factors they take into account to ensure vehicle stability. Data collection took place under actual conditions in five garages. A total of 108 lifting situations were filmed and analyzed, …

Le Parcours Des Travailleurs Immigrants Blessés Et Son Incidence Sur L’Alliance Thérapeutique : Une Étude De Cas Longitudinale En Contexte De Réadaptation Au Travail Au Québec, Maude Arsenault, Jessica Dubé, Daniel Côté

Études primaires

Cette étude explore l’incidence du parcours prélésionnel des travailleuses et travailleurs immigrants (TI) blessés sur l’alliance thérapeutique (AT) en réadaptation au travail. À partir d’une ethnographie longitudinale menée dans une clinique québécoise, sept trajectoires ont été analysées selon leurs dimensions migratoires, socioprofessionnelles et linguistiques. Les résultats montrent que le déclassement professionnel, la précarité de l’emploi, les barrières linguistiques et les expériences de racisme fragilisent la construction du lien de confiance et la définition partagée des objectifs de retour au travail. Lorsque l’emploi prélésionnel est perçu comme transitoire ou inadéquat, l’obligation institutionnelle d’y retourner crée une rupture symbolique qui entre en …

Tracking Vigilance While Driving: Pilot Study Of Heart Rate Variability Classification Under A Controlled Sleep-Deprivation Protocol, James Elber Duverger, Eli Moser, Philippe Boudreau, Marie Claude Ouimet, Diane B. Boivin, Alireza Saidi

Études primaires

Decreased vigilance associated with drowsiness is a major cause of motor vehicle crashes, but its physiological characterization and detection remain difficult due to behavioral and environmental confounding factors. This study presents an original experimental framework combining a highly controlled sleep-deprivation protocol, repeated driving simulations, and a machine-learning-based heart rate variability (HRV) analysis to study the physiological and behavioral changes in vigilance during a prolonged period of wakefulness while driving. Twelve healthy young adults participated in a 30-h sleep-deprivation constant routine protocol that included driving simulations every two hours, with data collection: electrocardiography (ECG), subjective ratings of drowsiness, psychomotor vigilance test, …

Prognostic Factors For Patients Under 45 Undergoing Surgery For Colorectal Liver Metastases: A Seer Population-Based Study, Gabrielle Grob, Fang Fang, Matvey Karpov, Eric Feliberti, Marybeth Hughes, Rachel Burke, Winifred Lo

Department Surgery Faculty Publications

Background and Objectives: Colorectal cancer (CRC) has been on the rise in adults younger than 50. Surgical resection is a potentially curative treatment option for patients with colorectal liver metastases (CRLM). The aim of this study was to describe patient and tumor characteristics associated with disease-specific survival in young patients (<  45 years) versus older patients (≥ 45 years) with isolated CRLM.

Methods: The SEER database was queried for patients with CRLM who underwent colon and liver resection from 2010 to 2021. Patients under age 20, with metastases beyond the liver, or who had not had surgery for liver metastases were excluded. Cox regression was used to analyze demographic factors, tumor …

The Performance Of Machine Learning Algorithms In Predicting Under-Five Anaemia In Tanzania, Henry Ofori Duah, Derrick Nyantakyi Owusu, Godwin G. Duah, Paul Shidende

College of Nursing Faculty Research and Publications

Aim

Anaemia in children under five remains a major public health concern, contributing significantly to global child morbidity and mortality. With the rise of machine learning (ML), novel opportunities exist to model and predict anaemia more effectively. This study aimed to evaluate and compare the performance of five ML algorithms in predicting anaemia among under-five children in Tanzania.

Methods

We conducted a secondary data analysis using the 2017 Tanzania Malaria Indicator Survey (TMICS). The dataset (n = 5906) was randomly split into training (70%) and test (30%) sets. Five ML algorithms, Linear Discriminant Analysis (LDA), Logistic Regression, Random Forest (RF), …

Facilitators And Barriers To Teach And Assess Clinical Judgment In The Context Of Ngn And Interpreted Through The Nln Framework, Patricia L. Pence, Seon Yoon Chung, Lisa D. Broderson, Vicki Moran, Myoungjin Kim

Faculty Publications - Mennonite College of Nursing

Background

The shift to Next Generation NCLEX (NGN) requires that nurse educators (NEs) align strategies to teach and assess clinical judgment (CJ). However, gaps remain in NEs' formal preparation to effectively teach and assess CJ as they prepare graduates for success on the evolving licensure examination.

Purpose

This study identified facilitators and barriers to teaching and assessing CJ within the context of NGN.

Method

A descriptive cross-sectional survey was conducted with 143 NEs across the United States (September 2022–April 2023). Findings were interpreted through the National League for Nursing (NLN) Core Competencies and Scope of Practice framework rather than reported …

Bridging The Knowledge-Practice Gap In Breast Cancer Awareness: A Nationwide Online Cross-Sectional Kap Study Among Adult Females In Nigeria, Madinat Hassan, Taofeek Tope Adegboyega, Bilkisu Usman Farouk, Sunday Zeal Bala, Rachael Olufunmilayo Oduyemi, Kazeem Owolabi, Munir Sani, Miracle Uwa Livinus, Hannatu Usman Ayuba, Sadiq Hassan, Ifeyinwa Maureen Okeke, Abednego Shekari, Murtala Jibril

Chemistry & Biochemistry Faculty Publications

Background and Aims

Breast cancer (BCa) is a major cause of cancer morbidity and mortality among women in Nigeria, with late presentation contributing to poor outcomes. This study assessed knowledge, attitudes, and willingness to perform breast self-examination (BSE) among adult females in Nigeria and examined associated factors.

Methods

We conducted a descriptive cross-sectional online survey between February 16 and April 30, 2024. A structured, pretested questionnaire was disseminated through digital platforms, yielding 711 consenting adult female respondents from all six geopolitical zones. Knowledge, attitude, and willingness-to-perform-BSE measures were analyzed using descriptive statistics, linear regression, and binary logistic regression. Associations were …

Interpretable Multimodal Zero Shot Ecg Diagnosis Via Structured Clinical Knowledge Alignment, Jialu Tang, Hung Manh Pham, Ignace De Lathauwer, Henk S. Schipper, Yuan Lu, Dong Ma, Aaqib Saeed

Research Collection School Of Computing and Information Systems

Electrocardiogram (ECG) interpretation is essential for cardiovascular disease diagnosis, but current automated systems often struggle with transparency and generalization to unseen conditions. To address this, we introduce ZETA, a zero-shot multimodal framework designed for interpretable ECG diagnosis aligned with clinical workflows. ZETA uniquely compares ECG signals against structured positive and negative clinical observations, which are curated through an LLM-assisted, expertvalidated process, thereby mimicking differential diagnosis. Our approach leverages a pre-trained multimodal model to align ECG and text embeddings without disease-specific fine-tuning. Empirical evaluations demonstrate ZETA’s competitive zero-shot classification performance and, importantly, provide qualitative and quantitative evidence of enhanced interpretability, grounding …