Medicine and Health Sciences Commons^™

Ua61/1 Wku Nursing Class 1992, Wku Nursing

WKU Administration Documents

Members of the 1992 nursing class: Mary Anderson, Diane Atwood, Rachelle Basham, Machell Borden, William Bouland, Nancy Bratcher, Tony Burba, Mary Christison, Debra Coffman, Winnie Evans, Rose Garrett, Tina Gawarecki, Darla Harwood, Denise Horn, Rebecca Hunt, Linda Kessinger, Betsy Kitchens, Tina Lashbrook, Marilyn Lindsey, Angela Lucas, Donna Marsh, Ilene Marshall, Arline Mutter, Cindy O'Malley, Michelle Parr, Carolyn Parrigan, Melody Prunty, Tammy Ragle, Beth Richardson, Rebecca Rose, William Russell, April Smith, David Tanaro, Dennis Tarter, Lynn Taylor, Jane Thomas, Katherine Tucker, Annette West, Helois West, C.J. Wheeler, Donna Whistle, Billy Whitaker, Lorie Whitaker, Beth Williams, Gwenetta Wilson and Annett Woodcock.

Ua12/12 Your Healthstyle, Wku Wellness Center

WKU Administration Documents

Newsletter created by the Wellness Center regarding services, health and fitness.

Ua12/4 Commuter Link, Vol. 1, No. 1, Wku Health Services

WKU Administration Documents

Newsletter created for non-traditional students returning to WKU.

How To Make A Blastocyst., A J Watson, G M Kidder, G A Schultz

Obstetrics & Gynaecology Publications

Several of the new reproductive technologies have been cultivated from our current understanding of the genetic programming and cellular processes that are involved in the major morphogenetic events of mammalian preimplantation development. Research directed at characterizing the patterns of gene expression during early development has shown that the embryo is initially under maternal control and later superseded by new transcriptional activity provided by the activation of the embryonic genome. Several embryonic transcripts encoding: (i) growth factors, (ii) cell junctions, (iii) plasma membrane ion transporters, and (iv) cell adhesion molecules have been identified as contributing directly to the progression of the …

Ua66/4/2 Allied Health Department Newsletter Issue No. 3, Wku Allied Health

WKU Administration Documents

Newsletter created by and about WKU Allied Health.

The Calendar - October 1992, Nova University

The Calendar

No abstract provided.

Modulation Of Cisplatin Sensitivity And Growth Rate Of An Ovarian Carcinoma Cell Line By Bombesin And Tumor Necrosis Factor-Alpha., Seiji Isonishi, Antti P. Jekunen, Doreen K. Hom, Alan Eastman, Peter S. Edelstein, Franz B. Thiebaut, Randolph D. Christen, Stephen B. Howell

Dartmouth Scholarship

A twofold change in the cisplatin (DDP) sensitivity of 2008 human ovarian carcinoma cells is sufficient to reduce tumor response in vivo. The DDP sensitivity of these cells can be enhanced by activation of the epidermal growth factor and protein kinase C signal transduction pathways. We report here that two endogenous growth factors, bombesin and tumor necrosis factor alpha (TNF alpha), enhanced DDP sensitivity by factors of 1.7 +/- 0.1 (SD)-fold and 1.8 +/- 0.1 (SD)-fold, respectively. Both agents also produced sensitization in an 11-fold DDP-resistant 2008 subline. Neither bombesin nor TNF alpha changed the accumulation of DDP, glutathione content, …

Jefferson Alumni Bulletin – Volume Xlii, Number 1, Fall 1992

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLII, Number 1, Fall 1992

New challenges are met successfully, page 2

The longitudinal study, page 4

Changes strengthen curriculum, page 6

Applications reach all-time high, page 7

The critical link between clinical practice and basic science, page 8

Drive to raise $200 million is in high gear, page 12

Hamilton professors are named, page 13

New Rorer professor, page 14

Endocrinology director appointed, page 14

Bequest from dubbs, ’31 establishes fellowships, page 15

New associate Dean, page 15

$5 million grant made to Jefferson cancer institute, page 16

President Brucker is welcomed in Washington, …

A Decade Of Aids Literature, Gregory F. Pratt

Library Staff Publications

From 1983 through mid-1991, more than 200,000 MEDLINE entries were AIDS-related. Close to 60% of the journals indexed in MEDLINE published at least one article on AIDS during the past ten years. As reflected by a subset of 29,077 MEDLINE records, the literature of AIDS has grown to encompass 29 languages and 65 countries. A bibliometric study of the medical literature helps to demonstrate the progression of AIDS as a world health problem and the concomitant expansion of the research effort underway to control it.

A Phorbol Ester Response Element Within The Human T-Cell Receptor Beta-Chain Enhancer., Haydn M. Prosser, David Wotton, Anne Gegonne, Jacques Ghysdael, Shuwen Wang, Nancy A. Speck, Michael J. Owen

Dartmouth Scholarship

The activity of the T-cell receptor beta-chain gene enhancer is increased by activators of the protein kinase C pathway during T-cell activation. Analysis of mutant enhancer constructs identified two elements, beta E2 and beta E3, conferring phorbol ester inducibility. Multimerized beta E2 acted in isolation as a phorbol ester-responsive element. Both beta E2 and beta E3, which contain a consensus Ets-binding site, were shown to bind directly to the product of the c-ets-1 protooncogene. Both regions also bound a second factor, core-binding factor. Mutation of the beta E2 Ets site abolished the inducibility of the beta E2 multimer. beta E2 …

Localization Of Cis-Acting Sequences In The Latency-Related Promoter Of Bovine Herpesvirus 1 Which Are Regulated By Neuronal Cell Type Factors And Immediate Early Genes, A. C. Bratanich, Clinton J. Jones

School of Veterinary and Biomedical Sciences: Faculty Publications

Bovine herpesvirus 1 (BHV-1) establishes a latent infection in sensory ganglionic neurons of cattle. During a latent infection, a single latency-related (LR) transcript is expressed. This observation suggested that DNA sequences in the LR promoter are positively regulated by neural cell type factors. The regulation of the LR gene was examined in neural cells as well as nonneural cells in transient assays. A 258-bp XbaI-SphI fragment from the LR promoter cis activated the herpes simplex virus type 1 thymidine kinase promoter in rat pheochromocytoma (PC-12) cells and differentiated human (HCNIA) neurons. In contrast, cis activation was not …

Evaluation Of The Ihs Urban Health Business Office Concept, American Indian Health Care Association, M.A. Foster

Native Health Database Full Text

Purpose The "Evaluation of the IHS Urban Health Business Office Concept," commonly called the Supplementary Security Income (SSI) Project, was a ten month grant demonstration project that was contracted to the American Indian Health Care Association (AIHCA) by the Indian Health Service (IHS) with cooperation of the Social Security Administration (SSA). The SSA was mandated to increase minority and target population enrollment for SSA benefits. The SSA provided funding to the IHS to oversee a project designed to locate and assist urban American Indians and Alaska Natives (AI/ANs) in applying for SSI.

Sex Selection: Regulating Technology Enabling The Predetermination Of A Child's Gender, Owen D. Jones

Vanderbilt Law School Faculty Publications

The debate over the prohibition of sex (or gender) selection (also known as "preselection" or "predetermination"), has focused almost exclusively on the context of aborting a "wrong-sex" fetus after a fetal gender-identification procedure. Despite the fact that sex selection abortions represent only a small subset of sex selection procedures, attitudes toward the former are driving general policy approaches to the latter. However, the issues are analytically distinct, and only during the former infancy of the pre-conceptive (and non-abortive post-conceptive) technology for sex selection were members on both sides of the debate afforded the economy of using one logic to support …

Labor Earnings, Discrimination, And The Racial Composition Of Jobs, Barry T. Hirsch, Edward J. Schumacher

Health Care Administration Faculty Research

This paper examines the effect of the racial composition of labor markets on wage rates and the racial wage gap. The wage rates of white as well as black workers are significantly lower in industry- occupation-regional groups with high densities of black workers, while the racial wage gap does not vary systematically with respect to racial density. Interpretation of racial gap estimates can be sensitive to inclusion of a racial density variable, particularly in sparse specifications. An explanation for the wagedensity relationship cannot be established, but results are most consistent with a quality sorting explanation and, to a lesser extent, …

Childhood Typhoid Fever Diagnosed In An Urban U.S. Setting., Surinder K. Sodhi, Stephen C. Eppes, Joel D. Klein

Department of Pediatrics Faculty Papers

The majority of cases of childhood typhoid fever diagnosed in the United States occur in persons recently returned from travel abroad. We report two childhood cases of typhoid fever acquired in Mexico and India and diagnosed in an urban United States setting. This report describes these cases and provides insights into the pitfalls in recognizing this condition in a nonendemic setting as well as information concerning differential diagnosis and treatment.

One-Trial Backward Excitatory Fear Conditioning Transfers Across Contexts, Rick A. Bevins, John J. B. Ayres

Department of Psychology: Faculty Publications

One path to human phobia may be one-trial backward fear conditioning. Human phobias transfer readily across contexts. However, animal studies of one-trial backward fear conditioning have yet to demonstrate such transfer. The present study sought to do so. It used a lick-suppression procedure with 84 naive male albino rats. Two conditioning contexts, designated O and V, were crossed factorially with two test contexts, O and V. Within each cell of the factorial design, rats received in the conditioning context either a single 12 sec tone backward paired with a single 4 sec 1 mA shock or the same tone explicitly …

Interactive And Higher-Order Effects Of Social Influences On Drug Use, Alan W. Stacy, Michael D. Newcomb, Peter M. Bentler

CGU Faculty Publications and Research

The study of moderators and higher-order effects of social influences on drug use has many implications for theories of health behavior. In the present study, we investigated the longitudinal predictive effects of some of the prominent moderator variables that represent forms of susceptibility toward social influence in teenage drug use. We also studied the possibility that social influence may predict drug use in nonlinear (quadratic) forms, consistent with theories proposing that threshold or decelerating effects may occur in social influences on normatively sanctioned behaviors. Results showed that several of the interactive and quadratic predictive effects were significant. The findings supported …

The Calendar - September 1992, Nova University

The Calendar

No abstract provided.

Gelatinase Activity In The Mouse Uterus During Early Pregnancy, Carol A. Brenner, Richard R. Adler, Gary L. Nieder

Neuroscience, Cell Biology & Physiology Faculty Publications

No abstract provided.

Yoghurt (Dahi): A Probiotic And Therapeutic View, Z Abbas, W Jafri

Section of Gastroenterology

No abstract provided.

Critical Thinking And Client Centered Nursing Care, Bernadette Q. Lavoie

Critical and Creative Thinking Capstones Collection

Critical and creative thinking skills are necessary for the new graduate and experienced nurses alike, if they are to respond to the rapidly changing health care system and deliver professional nursing care. Knowledge, generally speaking, is a resource not a constraint, but it becomes a constraint if it is not in the acceptable form. Consequently, knowledge alone is insufficient if the nurse clinician is unable to select the relevant information and defend its integration into client care. Skillful and perceptive nursing practice includes the ability to set and revise priorities for client care, manage actual and potential risks to individuals, …

On The Mechanism Of Parathyroid Hormone Stimulation Of Calcium Uptake By Mouse Distal Convoluted Tubule Cells, F A. Gesek, A. Friedman

Dartmouth Scholarship

PTH stimulates transcellular Ca2+ absorption in renal distal convoluted tubules. The effect of PTH on membrane voltage, the ionic basis of the change in voltage, and the relations between voltage and calcium entry were determined on immortalized mouse distal convoluted tubule cells. PTH (10(-8) M) significantly increased 45Ca2+ uptake from basal levels of 2.81 +/- 0.16 to 3.88 +/- 0.19 nmol min-1 mg protein-1. PTH-induced 45Ca2+ uptake was abolished by the dihydropyridine antagonist, nifedipine (10(-5) M). PTH did not affect 22Na+ uptake. Intracellular calcium activity ([Ca2+]i) was measured in cells loaded with fura-2. Control [Ca2+]i averaged 112 +/- 21 nM. …

Dementia Management: An Occupational Therapy Home-Based Intervention For Caregivers., Mary A. Corcoran, Laura N. Gitlin

Department of Occupational Therapy Faculty Papers

This paper describes an occupational therapy intervention designed for family caregivers of persons with dementia. The intervention, based on the framework of a competence-environmental press model and the principle of collaboration, was implemented during 5 home visits. Each visit was designed to build caregiving skills through collaboration in identifying problem areas, developing and implementing environmental strategies, and modifying management approaches. A case vignette illustrates the therapeutic process and outcomes. The theoretical rationale and structure of the intervention and innovative documentation for evaluation of the theoretic process are also presented.

Antibodies Against Epstein-Barr Nuclear Antigen (Ebna) In Multiple Sclerosis Csf, And Two Pentapeptide Sequence Identities Between Ebna And Myelin Basic Protein., Patrick F. Bray, J Luka, Paul F. Bray, K W. Culp, J P. Schlight

Cardeza Foundation for Hematologic Research

The Epstein-Barr virus (EBV) causes infectious mononucleosis and is linked to several disparate malignancies. Prior studies on patients with multiple sclerosis (MS) showed that 100% are EBV-seropositive and that their blood contains higher antibody titers than those of controls to both transformation and lytic cycle antigens. We performed three different assays for antibodies in CSF to three major EBV antigens from patients with MS and controls. Among 93 patients with MS, 79 (85%) had CSF that reacted with a 70 kD protein, shown to be the nuclear antigen, EBNA-1, whereas only 11 (13%) of 81 EBV-seropositive controls reacted, p less …

Sibling Confl Ict In Early Adolescence, Marcela Raffaelli

Department of Psychology: Faculty Publications

This study examined sibling conflict and relationship qualities in early adolescence. One hundred four 10- to 15-year-olds (mean age 11.7 years) completed questionnaires assessing the quality of their relationship with their closest sibling, and were interviewed about a recent, specific conflict with that sibling. Analysis suggests that sibling conflict fulfills several functions in early adolescence, including reinforcing family and relationship rules and delineating interpersonal boundaries. Few differences attributable to age or gender constellation of the sibling dyad emerged, and rivalry did not appear to be a primary impetus to conflict during this age period. Instead, sibling conflict appears to create …

Ua3/8 Raymond Preston Health & Activities Center Dedication, Wku President's Office

WKU Administration Documents

Dedication program for the Raymond Preston Health & Activities Center.

Ua3/8 Sneaker Preview, Wku President's Office

WKU Administration Documents

Program for the Raymond Preston Health & Activities Center sneak preview event.

Culturally Competent Occupational Therapy In A Diversely Populated Mental Health Setting, Maria Dillard, Lynne Andonian, Olivia Flores, Lisa Anne Lai, Anne Macrae, Muhjah Shakir

Faculty Publications

Cultural sensitivity is a crucial component of health care provision, particularly in psychiatric settings. As society becomes more multicultural, it is essential for occupational therapists to continue to develop cultural competence, which is defined in this paper as an awareness of, sensitivity to, and knowledge of the meaning of culture. At San Francisco General Hospital, an innovative multicultural model consisting of special focus programs is used. The key to the success of such programs is a culturally competent professional staff.

Ua3/8 Sneaker Preview Invitation, Wku President's Office

WKU Administration Documents

Invitation to Raymond Preston Health & Activities Center sneak preview event.

Re: Recertification., Geoffrey G. Hallock Md

Department of Surgery

No abstract provided.